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  1. Mutations in the human Ubiquilin 2 gene are associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) with or without frontotemporal dementia (FTD), the fatal neurodegenerative diseas...

    Authors: Patcharin Phokasem, Salinee Jantrapirom, Jirarat Karinchai, Hideki Yoshida, Masamitsu Yamaguchi and Panuwan Chantawannakul

    Citation: BMC Complementary Medicine and Therapies 2020 20:267

    Content type: Research article

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  2. Microbial infections are one of the major causes of death globally. This is attributed to the rising costs of primary healthcare and its inaccessibility especially in developing countries. Moreover, there has ...

    Authors: B. Ngobeni, S. S. Mashele, N. J. Malebo, E. van der Watt and I. T. Manduna

    Citation: BMC Complementary Medicine and Therapies 2020 20:266

    Content type: Research article

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  3. Ganluyin (GLY) is a famous classical prescription with a long history of use as a treatment for inflammatory conditions such as chronic pharyngitis (CP) in many parts of China. However, it has not been develop...

    Authors: Ye-Hui Chen, Rong Luo, Shan-Shan Lei, Bing Li, Fu-Chen Zhou, Hui-Ying Wang, Xue Chen, Xinglishang He, Yu-Zhi Wang, Liang-Hui Zhan, Ting-Ting Lu, Jie Su, Qiao-Xian Yu, Bo Li, Gui-Yuan Lv and Su-Hong Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:265

    Content type: Research article

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  4. The purpose of this study was to assess the antioxidative activity of selenium-enriched Chrysomyia Megacephala (Fabricius) (C. megacephala) larvae powder (SCML) and its impact on the diversity and structure of in...

    Authors: Dandan Xie, Liqin Jiang, Yao Lin and Zhenwei Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:264

    Content type: Research article

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  5. Atopic dermatitis (AD) is a worldwide chronic skin disease which burden public health. Sea buckthorn (SBT) (Hippophae rhamnoides L., Elaeagnaceae) oil, as a traditional herbal medicine, has been used for disease ...

    Authors: Xinxin Wang, Sijia Li, Jiping Liu, Dongning Kong, Xiaowei Han, Ping Lei, Ming Xu, Hongquan Guan and Diandong Hou

    Citation: BMC Complementary Medicine and Therapies 2020 20:263

    Content type: Research article

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  6. Triple-negative breast cancer (TNBC) is a kind of malignant tumor with higher recurrence and metastasis rate. According to historical records, the dry rhizomes Cyperus rotundus L. could be ground into powder and ...

    Authors: Shuangshuang Ma, Fukai Wang, Caijuan Zhang, Xinzhao Wang, Xueyong Wang and Zhiyong Yu

    Citation: BMC Complementary Medicine and Therapies 2020 20:262

    Content type: Research article

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  7. Dioscorea nipponica Makino is widely used in traditional Chinese medicine to treat gouty arthritis.

    Authors: Qi Zhou, Hui Juan Sun, Shu Min Liu, Xi Hong Jiang, Qiu Yue Wang, Shuang Zhang and Dong Hua Yu

    Citation: BMC Complementary Medicine and Therapies 2020 20:261

    Content type: Research article

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  8. African star apple (Chrysophyllum albidum) is a traditonal fruit, which is predominant in tropical regions with the fruit parts consumed by the populace and used in folklore to manage diabetes. However, the likel...

    Authors: Olubunmi B. Ajayi, Folake L. Oyetayo and Seun F. Akomolafe

    Citation: BMC Complementary Medicine and Therapies 2020 20:260

    Content type: Research article

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  9. The Sri Lankan traditional betel quid (TBQ) which had been extensively used in the country before its colonization is claimed to have antiperiodontopathic effects in the Sri Lankan folklore. However, there is ...

    Authors: Madhavi Priyanka Paranagama, Nadisha Sewwandi Piyarathne, Tharanga Lakmali Nandasena, Sumedha Jayatilake, Ayanthi Navaratne, Bandula Prasanna Galhena, Senani Williams, Jayantha Rajapakse and Kiyoshi Kita

    Citation: BMC Complementary Medicine and Therapies 2020 20:259

    Content type: Research article

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  10. Oral ulcer diseases are complex inflammatory diseases caused by multi-factors, which severely impact patient quality of life. Kouyanqing Granule (KYQG) has been used to treat inflammatory diseases of the mouth...

    Authors: Pan Chen, Hongliang Yao, Qing Yuan, Panlin Li, Xinning Wang, Weiwei Su, Yonggang Wang and Peibo Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:258

    Content type: Research article

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  11. Mulberry leaves are the dried leaves of Morus alba L., flavonoids from mulberry leaves (MLF) has showed regulatory effect on abnormal lipid metabolism, but the regulatory mechanism of MLF on cholesterol metabolis...

    Authors: Yucheng Hu, Jingqi Xu, Qian Chen, Mengyang Liu, Sijian Wang, Haiyang Yu, Yi Zhang and Tao Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:257

    Content type: Research article

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  12. Peganum harmala L. is a medicinal herb extensively used in traditional Chinese medicine (TCM). So far, relevant reports on the toxicity of Peganum harmala L. seeds (PHS) are hardly available. Especially, we still...

    Authors: Xiangzhen Miao, Xiao Zhang, Yanyan Yuan, Yali Zhang, Jian Gao, Nianxin Kang, Xinkui Liu, Jiarui Wu, Yonggang Liu and Peng Tan

    Citation: BMC Complementary Medicine and Therapies 2020 20:256

    Content type: Research article

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  13. Acori Tatarinowii Rhizome (ATR) is a well-recognized Chinese herbal medicine prescribed to treat neurological disorders. The essential oil (ATEO) is considered as the active fraction of ATR and the content of ...

    Authors: Lu Yan, Zhanzhan Liu, Li Xu, Yiyun Qian, Pingping Song and Min Wei

    Citation: BMC Complementary Medicine and Therapies 2020 20:255

    Content type: Research article

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  14. Primary insomnia (PI) is characterized by difficulties in initiating sleep or maintaining sleep, which lead to many serious diseases. Acupuncture for PI has drawn attention with its effectiveness and safety. H...

    Authors: Yu-Kai Wang, Tie Li, Li-Juan Ha, Zhong-Wen Lv, Fu-Chun Wang, Zhi-Hong Wang, Jing Mang and Zhong-Xin Xu

    Citation: BMC Complementary Medicine and Therapies 2020 20:254

    Content type: Research article

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  15. The prevalence and therapeutic effects of the use of herbal remedies for chronic liver diseases make the combined administration of herbal products with conventional treatment unable to be ignored. This study ...

    Authors: Tun-Pin Hsueh and Tung-Hu Tsai

    Citation: BMC Complementary Medicine and Therapies 2020 20:253

    Content type: Research article

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  16. Monoamine oxidase (MAO) A catalyzes oxidative deamination of monoamine neurotransmitters and dietary amines and regulates brain development and functions. Recently, we showed that MAO A mediates the progressio...

    Authors: Pei-Chuan Li, Shih-Yi Chen, Danzhou Xiangfei, Canquan Mao, Chieh-His Wu and Jean Chen Shih

    Citation: BMC Complementary Medicine and Therapies 2020 20:252

    Content type: Research article

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  17. Sulfated polysaccharides from marine algae are known to possess antioxidative activities, however, their therapeutic role in metal-induced neurodegeneration has not been explored. In this study, the neuroprote...

    Authors: Tosin A. Olasehinde, Ademola O. Olaniran and Anthony I. Okoh

    Citation: BMC Complementary Medicine and Therapies 2020 20:251

    Content type: Research article

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  18. Psoriasis is a common inflammatory skin disease. Abnormal proliferation of keratinocytes is one of the psoriatic histopathological features. Indirubin has an essential effect on the proliferation and activatio...

    Authors: Shou Gang Liu, Guang Pu Luo, Yong Bin Qu and Yong Feng Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:250

    Content type: Research article

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  19. Polycystic ovary syndrome (PCOS) is a common endocrine disorder. The aim of the present study was to evaluate the effects of the oral administration of thylakoid-rich spinach extract and the caraway aqueous ex...

    Authors: Saeed Sherafatmanesh, Maryam Ekramzadeh, Nader Tanideh, Mohammad-Taghi Golmakani and Farhad Koohpeyma

    Citation: BMC Complementary Medicine and Therapies 2020 20:249

    Content type: Research article

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  20. Chinese Medicine education is part of professional medical training in Hong Kong. An important element of this is herbal medicine, which requires both theoretical and practical knowledge. A field trip programm...

    Authors: Lei Li, Chi Wing Tam, Ning Wang, Fan Cheung, Qing Zhou, Cheng Zhang, Chien-shan Cheng, Lei Xiong and Yibin Feng

    Citation: BMC Complementary Medicine and Therapies 2020 20:248

    Content type: Research article

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  21. Self-care refers to a range of activities and approaches undertaken by an individual to maintain health and manage ill-health which may include various complementary or alternative approaches. The purpose of t...

    Authors: Karen Pilkington and Lisa Susan Wieland

    Citation: BMC Complementary Medicine and Therapies 2020 20:247

    Content type: Research article

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  22. Plant species from the genus Tecoma are found in tropical and subtropical regions around the world. Some of them are grown as ornamental plants and others can be used as medicinal plants. In the present study, et...

    Authors: Adriana Cotta Cardoso Reis, Breno Mello Silva, Hélia Maria Marques de Moura, Guilherme Rocha Pereira and Geraldo Célio Brandão

    Citation: BMC Complementary Medicine and Therapies 2020 20:246

    Content type: Research article

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  23. At present, ursodeoxycholic acid (UDCA) is internationally recognized as a therapeutic drug in clinic. However, about 40% Primary Biliary Cholangitis (PBC) patients are poor responders to UDCA. It has been dem...

    Authors: Hui Yang, Hang Yang, Lixia Wang, Honggang Shi, Bojia Liu, Xue Lin, Qingyong Chang, Jiande D. Z. Chen and Zhijun Duan

    Citation: BMC Complementary Medicine and Therapies 2020 20:242

    Content type: Research article

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  24. The use of Chinese herbal medicine (CHM) has been widely promoted as a natural and safe way to treat illness during pregnancy. However, prescription patterns and factors influencing its use are largely unknown...

    Authors: Shu-Hui Wen, Wei-Chuan Chang, Hsuan-Shu Shen and Hsien-Chang Wu

    Citation: BMC Complementary Medicine and Therapies 2020 20:240

    Content type: Research article

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  25. Immunomodulatory effects of Tinospora crispa have been investigated due to its traditional use to treat several inflammatory disorders associated to the immune system. The present study reports the underlying mec...

    Authors: Md. Areeful Haque, Ibrahim Jantan, Hemavathy Harikrishnan and Waqas Ahmad

    Citation: BMC Complementary Medicine and Therapies 2020 20:245

    Content type: Research article

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  26. Stroke is one of the major causes of death and disability. The treatments that are provided to patients during hospitalization after an acute stroke are very important in stabilizing their medical condition an...

    Authors: Wei-Sen Chen, Hung-Chih Hsu, Yi-Wen Chuang, Meng Lee, Kuan-Yu Lu, Yi-Fei Chen and Chien-Min Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:244

    Content type: Research article

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  27. Lung cancer has the highest morbidity and mortality in the world and novel treatment strategies are still needed. Haimufang decoction (HMF) is a patented clinical prescription of traditional Chinese medicine f...

    Authors: Wei-Ping Ma, Shu-Man Hu, Yan-Lai Xu, Hai-Hua Li, Xiao-Qing Ma, Bao-Hong Wei, Fu-Yu Li, Hua-Shi Guan, Guang-Li Yu, Ming Liu and Hong-Bing Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:243

    Content type: Research article

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  28. Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of...

    Authors: Yasaman Taheri, Hafiz Ansar Rasul Suleria, Natália Martins, Oksana Sytar, Ahmet Beyatli, Balakyz Yeskaliyeva, Gulnaz Seitimova, Bahare Salehi, Prabhakar Semwal, Sakshi Painuli, Anuj Kumar, Elena Azzini, Miquel Martorell, William N. Setzer, Alfred Maroyi and Javad Sharifi-Rad

    Citation: BMC Complementary Medicine and Therapies 2020 20:241

    Content type: Review

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  29. While there are several existing eHealth technologies for drug-drug interactions and stand-alone drug adverse effects, it appears that considerably less attention is focussed on that of complementary and alter...

    Authors: Jeremy Y. Ng, Maryam Mooghali and Vanessa Munford

    Citation: BMC Complementary Medicine and Therapies 2020 20:239

    Content type: Research article

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  30. The current antimicrobial therapy is still important for the treatment of pneumonia due to MRSA infection, but there are some limitations, including the route of administration, side effect profile, and increa...

    Authors: Ryong Kong, Young-Seob Lee, Dam-Hee Kang, Shu Wang, Qianqian Li, Dong-Yeul Kwon and Ok-Hwa Kang

    Citation: BMC Complementary Medicine and Therapies 2020 20:238

    Content type: Research article

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    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2020 20:311

  31. Analgesic, anti-inflammatory, and sedative drugs are available with potential side effects such as peptic ulcer and addiction among other things. In this regard, research is underway to find safe, effective, a...

    Authors: Abdur Rauf, Tareq Abu-Izneid, Fahad A. Alhumaydhi, Naveed Muhammad, Abdullah S. M. Aljohani, Saima Naz, Saud Bawazeer, Abdul Wadood and Mohammad S. Mubarak

    Citation: BMC Complementary Medicine and Therapies 2020 20:237

    Content type: Research article

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  32. Bee pollen (BP) has been used as a traditional medicine and food diet additive due to its nutritional and biological properties. The potential biological properties of bee pollen vary greatly with the botanica...

    Authors: Yuchi Zou, Jian Hu, Wenting Huang, Liyun Zhu, Mingjie Shao, Confidence Dordoe, Young-Joon Ahn, Dongxue Wang, Yeli Zhao, Ye Xiong and Xue Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:236

    Content type: Research article

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  33. Curcumin can inhibit the osteoclastogenesis and the migration of several cells including macrophages. Osteoclast precursors (OCPs) are known to exist as bone marrow-derived macrophages (BMMs). This study aims ...

    Authors: Zhengeng Liang, Yan Xue, Tao Wang, Qi Xie, Jiafu Lin and Yu Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:234

    Content type: Research article

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  34. Urinary tract infections (UTIs) caused by opportunistic pathogens are among the leading health challenges globally. Most available treatment options are failing as a result of antibiotic resistance and adverse...

    Authors: Aitebiremen G. Omokhua-Uyi, Muna A. Abdalla, Carmen M. Leonard, Abimbola Aro, Osariyekemwen O. Uyi, Johannes Van Staden and Lyndy J. McGaw

    Citation: BMC Complementary Medicine and Therapies 2020 20:233

    Content type: Research article

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  35. Field cricket (Gryllus bimaculatus) is newly emerged as an edible insect in several countries. Anti-inflammatory effect of glycosaminoglycan derived from this cricket on chronic disease animal model such as diabe...

    Authors: Mi Young Ahn, Ban Ji Kim, Ha Jeong Kim, Jang Mi Jin, Hyung Joo Yoon, Jae Sam Hwang and Byung Mu Lee

    Citation: BMC Complementary Medicine and Therapies 2020 20:232

    Content type: Research article

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  36. There is a lack of data on the use of complementary and alternative medicine (CAM) in patients with coronary heart disease (CHD). This study examined the use of CAM among patients with CHD, the reasons and fac...

    Authors: Abdelraouf O. Salah, Ahmad D. Salameh, Mohanad A. Bitar, Sa’ed H. Zyoud, Abdulsalam S. Alkaiyat and Samah W. Al-Jabi

    Citation: BMC Complementary Medicine and Therapies 2020 20:231

    Content type: Research article

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  37. The human placenta (HP) is a complex organ used to alleviate tiredness and promote wound healing. Previous research showed the hair growth-promoting effect of HP. However, no reports have addressed the effects...

    Authors: Mi Hye Kim, Kyuseok Kim, Haesu Lee and Woong Mo Yang

    Citation: BMC Complementary Medicine and Therapies 2020 20:230

    Content type: Research article

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  38. Thyroid-associated ophthalmopathy (TAO) is an autoimmune inflammatory disorder, which lacks effective treatment currently. Spica Prunellae (SP) is popularly used for its anti-inflammatory and immune-regulating...

    Authors: Yuhan Zhang, Xianzhi Li, Congcong Guo, Jianjun Dong and Lin Liao

    Citation: BMC Complementary Medicine and Therapies 2020 20:229

    Content type: Research article

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  39. Hyssopus cuspidatus Boriss has been used as an important ethnomedicinal plant for long to eliminate phlegm, relieve cough and as well as having antibacterial, antioxygenation, and antitumor activities. In this st...

    Authors: Lu Zhao, Zhihong Ji, Keao Li, Bo Wang, Ya Zeng and Shuge Tian

    Citation: BMC Complementary Medicine and Therapies 2020 20:228

    Content type: Research article

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  40. The roots of Pueraria lobata and Scutellaria baicalensis, herbal medicines with a long history of widespread use, have been traditionally prescribed in combination to treat stroke, diabetes, and acute infectious ...

    Authors: Jungbin Song, Young-Sik Kim, Donghun Lee and Hocheol Kim

    Citation: BMC Complementary Medicine and Therapies 2020 20:226

    Content type: Research article

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  41. Osteoarthritis (OA) is the commonest form of inflammatory joint disease. Unfortunately, to date, there is no appropriate treatment for OA. Boswellia serrata was considered as a potent anti-inflammatory, anti-arth...

    Authors: Ganpeng Yu, Wang Xiang, Tianqing Zhang, Liuting Zeng, Kailin Yang and Jun Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:225

    Content type: Research article

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  42. Overactive bladder is defined as “urgency, with or without urge incontinence, usually with frequency and nocturia”. Electroacupuncture may be a safe and an effective alternative therapy for overactive bladder,...

    Authors: Qian Wen, Ning Li, Xueling Wang, Hao Li, Fengwei Tian, Weiwei Chen, Yanyan Lu and Zhishun Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:224

    Content type: Study protocol

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  43. Integrative medicine (IM), which is the integration of complementary and alternative medicine (CAM) into conventional health services, has been applied in some nations. Despite its highly relevant holistic app...

    Authors: Andrian Liem

    Citation: BMC Complementary Medicine and Therapies 2020 20:223

    Content type: Research article

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  44. Statins are considered as standard drugs to control cholesterol levels, but their use is also associated with renal hypertrophy, hemorrhagic stroke, hepatomegaly, and myopathy. Murraya koenigii is an herb that is...

    Authors: Gul Ambreen, Afshan Siddiq, Kashif Hussain, Abdul Saboor Hussain and Zara Naz

    Citation: BMC Complementary Medicine and Therapies 2020 20:222

    Content type: Research article

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  45. Liver cirrhosis is one of the main causes of the morbidity and mortality in liver diseases. Chinese herbal medicine (CHM) has long been used for the clinical treatment of liver diseases. This study was designe...

    Authors: Fuu-Jen Tsai, Pei-Yuu Yang, Chao-Jung Chen, Ju-Pi Li, Te-Mao Li, Jian-Shiun Chiou, Chi-Fung Cheng, Po-Heng Chuang, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Bo Ban, Wen-Miin Liang and Ying-Ju Lin

    Citation: BMC Complementary Medicine and Therapies 2020 20:221

    Content type: Research article

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  46. The present study aimed to assess the perturbation in circular RNA (circRNA)/mRNA expression profiles and a circRNA-miRNA-mRNA coexpression network involved in the potential protective effect of diosgenin (DIO...

    Authors: Zhiguo Zhang, Lifeng Yue, Yuhan Wang, Yanhua Jiang, Lihua Xiang, Yin Cheng, Dahong Ju and Yanjing Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:220

    Content type: Research article

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  47. The use of complementary and alternative medicine (CAM) among type 2 diabetes mellitus (T2DM) patients is increasing worldwide. It can affect optimum glycemic management. This study was to determine the rate a...

    Authors: Md. Abdur Rafi, Dewan Tasnia Azad, Mridula Bhattacharjee, Nikita Rahman, Kazi Abdul Mubin, Md. Ajijur Rahman and Md. Golam Hossain

    Citation: BMC Complementary Medicine and Therapies 2020 20:219

    Content type: Research article

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  48. Abnormal renal metabolism is closely related to the development of chronic kidney disease. It is well known that renal inflammation plays an important role in the occurrence and development of tubulointerstiti...

    Authors: Jiao-xia Wu, An Jia, Yin-feng Tan, Han Xu, Jian-ping Tian, Yan Wang, Hai Long Li, Bing-miao Gao and Yong-hui Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:217

    Content type: Research article

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