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  1. The Prinsepia utilis Royle leaves (P. utilis) is a folk herb used for benign prostatic hyperplasia (BPH) control by ethnic minorities for centuries in China with rich in resources. Our previous studies have confi...

    Authors: Ying Peng, Chongsheng Peng, Yang Wu, Chongzhi Sun and Xiaobo Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:272
  2. We previously showed that enzymatically hydrolyzed Dendropanax morbiferus H. Lév. leaf (Hy-DP) and unripe Rubus coreanus Miq. (5-uRCK) extracts exhibit potent vasodilator effects on isolated aortic rings from rat...

    Authors: Soyi Park, Ki Hoon Lee, Hakjoon Choi, Goeun Jang, Wan Seok Kang, Eun Kim, Jin Seok Kim, Chang-su Na and Sunoh Kim
    Citation: BMC Complementary Medicine and Therapies 2021 21:271
  3. Diabetes mellitus is a common disease effecting the lifestyles of majority world population. In this research work, we have embarked the potential role of crude extracts and isolated compounds of Notholirion thom...

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Ali O. Alqarni, Bandar A. Alyami, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Umer Rashid and Abdul Sadiq
    Citation: BMC Complementary Medicine and Therapies 2021 21:270
  4. The present study extensively aimed to evaluate the underlying mechanism of the immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium (PLM).

    Authors: Mi-Rae Shin, Ji Hye Lee, Jin A Lee, Min Ju Kim, Hae-Jin Park, Byeong Wook Park, Seung Bo Seo and Seong-Soo Roh
    Citation: BMC Complementary Medicine and Therapies 2021 21:269
  5. Use of herbal medicines during pregnancy has been increase in many developing and developed countries. In spite of the studies done on herbal medicine, no study has addressed use of herbal medicine among pregn...

    Authors: Getu Tesfaw Addis, Birhanu Demeke Workneh and Mesfin Haile Kahissay
    Citation: BMC Complementary Medicine and Therapies 2021 21:268
  6. Alzheimer’s disease (AD) is the most common dementia worldwide, and there is still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese medicine with multiple neuroprotective...

    Authors: Xiao-feng Wang, Hong-he Xiao, Yu-tong Wu, Liang Kong, Ji-cong Chen, Jing-xian Yang and Xiao-le Hu
    Citation: BMC Complementary Medicine and Therapies 2021 21:267
  7. Authors: Sanya Haiaty, Mohammad-Reza Rashidi, Maryam Akbarzadeh, Ahad Bazmani, Mostafa Mostafazadeh, Saba Nikanfar, Zohre Zibaei, Reza Rahbarghazi and Mohammad Nouri
    Citation: BMC Complementary Medicine and Therapies 2021 21:266

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:83

  8. Oils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases ...

    Authors: Fatemeh Saghafi, Farzaneh Mirzaie, Elham Gorji, Razieh Nabimeybodi, Mehdi Fattahi, Hamed Mahmoodian and Rahele Zareshahi
    Citation: BMC Complementary Medicine and Therapies 2021 21:265
  9. Physiotherapists (PTs) across the globe are increasingly incorporating filiform needling techniques (e.g., acupuncture, dry needling) into their clinical toolkits; and, the evidence base for these complementar...

    Authors: Nadine Ijaz, Sandy Welsh and Heather Boon
    Citation: BMC Complementary Medicine and Therapies 2021 21:264
  10. Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death. Traditional Chinese medicine (TCM) has special advantages in relieving HCC, while Astragalus membranaceus is commonly used in TC...

    Authors: Zhili Liu, Huihan Ma and Zelin Lai
    Citation: BMC Complementary Medicine and Therapies 2021 21:263
  11. Lack of information exists about the use of traditional and complementary medicine (TCM) use among middle-aged and older adults in India, which led to studying the estimates of past-12-month Ayurveda/Yoga/Natu...

    Authors: Supa Pengpid and Karl Peltzer
    Citation: BMC Complementary Medicine and Therapies 2021 21:262
  12. Osteoarthritis (OA) is the most common form of arthritis, affecting millions of people worldwide and characterised by joint pain and inflammation. It is a complex disease involving inflammatory factors and aff...

    Authors: Sybille Brochard, Julien Pontin, Benoit Bernay, Karim Boumediene, Thierry Conrozier and Catherine Baugé
    Citation: BMC Complementary Medicine and Therapies 2021 21:261
  13. Current therapy of chronic hepatitis C virus (HCV) with direct-acting antivirals (DAAs) has dramatically improved the sustained virologic response (SVR) of affected patients; however, treatment with DAAs remai...

    Authors: Adita Ayu Permanasari, Chie Aoki-Utsubo, Tutik Sri Wahyuni, Lidya Tumewu, Myrna Adianti, Aty Widyawaruyanti, Hak Hotta and Achmad Fuad Hafid
    Citation: BMC Complementary Medicine and Therapies 2021 21:260
  14. According to recent evidence, psychobiotics exert beneficial effects on central nervous system-related diseases, such as mental disorders. Lactobacillus plantarum PS128 (PS128), a novel psychobiotic strain, impro...

    Authors: Hei-Jen Huang, Jie-Ling Chen, Jian-Fu Liao, Yu-Hsin Chen, Min-Wei Chieu, Ya-Yun Ke, Chih-Chieh Hsu, Ying-Chieh Tsai and Hsiu Mei Hsieh-Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:259

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:136

  15. Buchholzia coriacea Engl. is popularly called wonderful cola due to its wide ethnomedicinal use for the treatment of various ailments. We investigated the possible cytotoxic effect of its various fractions on hu...

    Authors: Hope Onohuean, Rahmat Adetutu Adisa and Abdullateef Isiaka Alagbonsi
    Citation: BMC Complementary Medicine and Therapies 2021 21:258
  16. Oxidative stress-induced injury during hypothermic preservation is a universal problem that delays graft function and decrease the success of organ transplantation. Tanshinone IIA (Tan IIA) was reported to exh...

    Authors: Linhao Xu, Yizhou Xu, Zhoujing Zhu, Huiquan Gu, Chaofeng Chen and Jian Chen
    Citation: BMC Complementary Medicine and Therapies 2021 21:257
  17. Microbial resistance, diabetes mellitus, and obesity are global health care problems that have posed a serious threat to both human and environmental ecosystems. The goals of the present investigations are to ...

    Authors: Nidal Jaradat, Mohammad Qadi, Iyad Ali, Fatima Hussein, Linda Issa, Doaa Rashdan, Manal Jamoos, Re’as Najem, Abdulraziq Zarour and Mohammad Arar
    Citation: BMC Complementary Medicine and Therapies 2021 21:256
  18. Adipose tissue is a critical regulator of lipid storage and endocrine function. Impairment of the recruitment of new adipocytes in the adipose tissue is associated with ectopic fat accumulation, diabetes and i...

    Authors: Eunbi Koh, Boram Kim and Kyungoh Choi
    Citation: BMC Complementary Medicine and Therapies 2021 21:255
  19. Eucalyptol is an active compound of eucalyptus essential oil and was reported to have many medical attributes including cytotoxic effect on breast cancer cells. However, it has low solubility in aqueous soluti...

    Authors: Mira Nadiah Mohd Izham, Yazmin Hussin, Nurul Fattin Che Rahim, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah and Noorjahan Banu Alitheen
    Citation: BMC Complementary Medicine and Therapies 2021 21:254
  20. Episiotomy is the most commonn surgical procedure in midwifery which as any other wounds can cause infection or delay in healing.

    Authors: Elmira Toomari, Sepideh Hajian, Faraz Mojab, Tayebe Omidkhah and Malihe Nasiri
    Citation: BMC Complementary Medicine and Therapies 2021 21:253
  21. While evidence-based practice (EBP) is widely accepted across healthcare professions, research investigating its implementation in manual therapy professions such as osteopathy is limited. The primary aim of t...

    Authors: Francesco Cerritelli, Alessio Iacopini, Matteo Galli, Oliver P. Thomson, Tobias Sundberg, Matthew J. Leach and Jon Adams
    Citation: BMC Complementary Medicine and Therapies 2021 21:252
  22. Mild cognitive impairment (MCI) is considered an intermediate phase between normal aging and dementia. As the majority of cases of amnestic MCI (aMCI) progress to Alzheimer’s disease (AD), it is considered the...

    Authors: Hee-Yeon Shin, Ha-Ri Kim, Geon-Ho Jahng, Chul Jin, Seungwon Kwon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Chang-Nam Ko and Jung-Mi Park
    Citation: BMC Complementary Medicine and Therapies 2021 21:251
  23. Complementary and integrative medical procedures (CIM) play an important role in general practice (GP). Consequently, in some countries (e.g. USA, Australia) specific curricula for the integration of CIM compe...

    Authors: Jan Valentini, Carina Klocke, Corina Güthlin and Stefanie Joos
    Citation: BMC Complementary Medicine and Therapies 2021 21:250
  24. More than 80% of the African population depend on traditional medicine as a primary healthcare. Although the African migrant community is increasing in Australia, there is no research documenting if and how Af...

    Authors: Zewdneh Shewamene, Tinashe Dune and Caroline A. Smith
    Citation: BMC Complementary Medicine and Therapies 2021 21:249
  25. Edible oils have proven health benefits in the prevention and treatment of various disorders since the establishment of human era. This study was aimed to appraise neuropharmacological studies on the commonly ...

    Authors: Mater H. Mahnashi, Bandar A. Alyami, Yahya S. Alqahtani, Ali O. Alqarni, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Muhammad Shahid, Umer Rashid and Abdul Sadiq
    Citation: BMC Complementary Medicine and Therapies 2021 21:248
  26. This study aimed to investigate the prevalence of and the factors associated with the regular use of complementary therapies for Taiwanese patients with systemic lupus erythematosus (SLE).

    Authors: Ming-Chi Lu, Hui-Chin Lo, Hsiu-Hua Chang, Chia-Wen Hsu and Malcolm Koo
    Citation: BMC Complementary Medicine and Therapies 2021 21:247
  27. Influenza A virus (IAV) infection is a continual threat to the health of animals and humans globally. Consumption of the conventional drugs has shown several side effects and drug resistance. This study was ai...

    Authors: Parvaneh Mehrbod, Hanieh Safari, Zeinab Mollai, Fatemeh Fotouhi, Yasaman Mirfakhraei, Hanieh Entezari, Saied Goodarzi and Zahra Tofighi
    Citation: BMC Complementary Medicine and Therapies 2021 21:246
  28. Adaptive metabolic response towards a low oxygen environment is essential to maintain rapid tumour proliferation and progression. The vascular network that surrounds the tumour develops an intermittent hypoxic...

    Authors: S. H. Shahruzaman, F. Z. Yusof, S. Maniam, S. Fakurazi and S. Maniam
    Citation: BMC Complementary Medicine and Therapies 2021 21:245
  29. The present study aims to investigate the knowledge, attitude, and performance of Iranian Healthcare Professionals (HP) about Complementary and Alternative Medicine (CAM) modalities.

    Authors: Alireza Jafari, Mohaddeseh Zanganeh, Zahra Kazemi, Elaheh Lael-Monfared and Hadi Tehrani
    Citation: BMC Complementary Medicine and Therapies 2021 21:244
  30. Quercetin and H19 can promote osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). However, whether quercetin regulates H19 expression to promote osteogenic differentiation of BMSCs is unc...

    Authors: Wei Bian, Shunqiang Xiao, Lei Yang, Jun Chen and Shifang Deng
    Citation: BMC Complementary Medicine and Therapies 2021 21:243
  31. Liquidambaris Fructus (LF) is the infructescence of Liquidambar formosana. In Traditional Chinese Medicine, LF has been used to treat joint pain, a common symptom of arthritis and rheumatism; however, a lack of p...

    Authors: Wen-xuan Li, Ping Qian, Yi-tong Guo, Li Gu, Jessore Jurat, Yang Bai and Dong-fang Zhang
    Citation: BMC Complementary Medicine and Therapies 2021 21:242
  32. Authors: Elaissi Ameur, Moumni Sarra, Derbali Yosra, Khouja Mariem, Abid Nabil, Frederic Lynen and Khouja Mohamed Larbi
    Citation: BMC Complementary Medicine and Therapies 2021 21:241

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:209

  33. As a prevalent type of cryptogenic fibrotic disease with high mortality, idiopathic pulmonary fibrosis (IPF) still lacks effective therapeutic drugs. The compounds extracted from buds and flowers of Chrysanthemum...

    Authors: Juan Nie, Yanlu Liu, Chaoyue Sun, Jingna Zheng, Baoyi Chen, Jianyi Zhuo, Ziren Su, Xiaoping Lai, Jiannan Chen, Jibiao Zheng and Yucui Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:240
  34. According to the recent global cancer statistics, breast cancer is the leading cause of deaths among women with 2.3 million new cases globally. Likewise, cervical cancer is also among the leading causes of mor...

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Bandar A. Alyami, Ali O. Alqarni, Farhat Ullah, Abdul Wadood, Abdul Sadiq, Azam Shareef and Muhammad Ayaz
    Citation: BMC Complementary Medicine and Therapies 2021 21:239
  35. This study evaluated the in vitro antioxidant activity and comparison of anti-inflammatory and cytotoxic activity of Harpagopytum zeyheri with diclofenac.

    Authors: Sibonokuhle F. Ncube, Lyndy J. McGaw, Emmanuel Mfotie Njoya, Hilton G. T. Ndagurwa, Peter J. Mundy and Samson Sibanda
    Citation: BMC Complementary Medicine and Therapies 2021 21:238
  36. Vulvovaginal candidiasis (VVC), the second leading cause of genital infection in women of reproductive age, is caused by yeasts of the genus Candida. Treatment is usually empirical and performed with azoles, whic...

    Authors: Aline Lorenzoni Paniágua, Amabel Fernandes Correia, Lívia Custódio Pereira, Bruna Maciel de Alencar, Fabiana Brandão Alves Silva, Rosane Mansan Almeida and Yanna Karla de Medeiros Nóbrega
    Citation: BMC Complementary Medicine and Therapies 2021 21:237
  37. Globally, 3 billion people suffer from either migraine or tension-type headache disorder over their lifetime. Approximately 50% of American adults suffering from headache or migraine have used complementary an...

    Authors: Jeremy Y. Ng and Christina Hanna
    Citation: BMC Complementary Medicine and Therapies 2021 21:236
  38. Siraitia grosvenorii (binomial name Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang), also called Arhat Fruit or Monk’s Fruit, is a dried ripe fruit belonging to the Cucurbitaceae Family. S. grosve...

    Authors: Wei Dong, Jia Zeng, Qin Wang, Xin Jiang and Ting Huang
    Citation: BMC Complementary Medicine and Therapies 2021 21:235
  39. Uvaria chamae (UC) and Olax subscorpioidea (OS) roots are included in traditional anti-cancer remedies and some studies have identified their chemopreventive/chemotherapeutic potential. This study aimed to identi...

    Authors: Temidayo D. Popoola, Stephanie T. Guetchueng, Kenneth J. Ritchie, Olufunsho Awodele, Nicola M. Dempster, Oluyemi Akinloye, Satyajit D. Sarker and Amos A. Fatokun
    Citation: BMC Complementary Medicine and Therapies 2021 21:234
  40. The global prevalence of diabetes mellitus is projected to reach approximately 700 million by the year 2045, with roughly 90–95% of all diabetes cases being type 2 in nature. Patients with type 2 diabetes mell...

    Authors: Jeremy Y. Ng, Manav Nayeni and Kevin Gilotra
    Citation: BMC Complementary Medicine and Therapies 2021 21:233
  41. One of the most prevalent complications of chemotherapy and radiotherapy is oral mucositis (OM) and manifests as erythema and ulceration. Curcumin is one of the components of turmeric and possesses anti-inflam...

    Authors: Seyed Javad Kia, Maryam Basirat, Hamid Saeidi Saedi and Seyed Ali Arab
    Citation: BMC Complementary Medicine and Therapies 2021 21:232
  42. Neorautanenia mitis, Hydnora abyssinica, and Senna surattensis are medicinal plants with a variety of traditional uses. In this study, we sought to isolate the bioactive compounds responsible for some of these ac...

    Authors: Christiana J. Dawurung, Minh T. H. Nguyen, Jutharat Pengon, Kanchana Dokladda, Ratchanu Bunyong, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Phuong T. M. Nguyen and Stephen G. Pyne
    Citation: BMC Complementary Medicine and Therapies 2021 21:231
  43. Little is known about the medical material and practices of tribes in the western border areas of Pakistan. The local population has inhabited this remote and isolated area for centuries, and gained medicinal ...

    Authors: Khalid Ahmad, Mushtaq Ahmad, Franz K. Huber and Caroline S. Weckerle
    Citation: BMC Complementary Medicine and Therapies 2021 21:230
  44. We previously reported that the tomato glycoalkaloid tomatine inhibited the growth of Trichomonas vaginalis strain G3, Tritrichomonas foetus strain D1, and Tritrichomonas foetus-like strain C1 that cause disease ...

    Authors: Christina C. Tam, Kevin Nguyen, Daniel Nguyen, Sabrina Hamada, Okhun Kwon, Irene Kuang, Steven Gong, Sydney Escobar, Max Liu, Jihwan Kim, Tiffany Hou, Justin Tam, Luisa W. Cheng, Jong H. Kim, Kirkwood M. Land and Mendel Friedman
    Citation: BMC Complementary Medicine and Therapies 2021 21:229
  45. Traditional Chinese Medicine (TCM) has been a proposed treatment option for ulcerative colitis (UC), however it has been difficult to understand the breadth and depth of evidence as various Chinese medicine th...

    Authors: Yu-Xin Sun, Xiao Wang, Xing Liao, Jing Guo, Wen-Bin Hou, Xin Wang, Jian-Ping Liu and Zhao-Lan Liu
    Citation: BMC Complementary Medicine and Therapies 2021 21:228
  46. Leucas cephalotes is a common ethnomedicinal plant widely used by traditional healers for the treatment of Malaria and other types of fever. Oleanolic acid and its derivatives have been reported for various types...

    Authors: Sulochana Kaushik, Lalit Dar, Samander Kaushik and Jaya Parkash Yadav
    Citation: BMC Complementary Medicine and Therapies 2021 21:227
  47. Atopic dermatitis (AD) is a chronic inflammatory skin disease mainly caused by immune stimuli. The current study was conducted to investigate the effects of ROCEN and to compare it with betamethasone (Beta) on...

    Authors: Ramin Goudarzi, Maryam Eskandarynasab, Ahad Muhammadnejad, Ahmad Reza Dehpour and Alireza Partoazar
    Citation: BMC Complementary Medicine and Therapies 2021 21:226
  48. Cisplatin is an outstanding anticancer drug, but its use has been decreased remarkably due to sever nephrotoxicity. R. vesicarius L. is a leafy vegetable that is evident with anti-angeogenic, anti-inflammatory, a...

    Authors: Md. Mahmudul Hasan, Most. Sayla Tasmin, Ahmed M. El-Shehawi, Mona M. Elseehy, Md. Abu Reza and Ariful Haque
    Citation: BMC Complementary Medicine and Therapies 2021 21:225
  49. Oleanolic acid (OA) has multiple pharmaceutical applications including anti-inflammatory activity, but low permeability of the molecule limits its widespread use.

    Authors: Zhiqi Shi, Shugang Pan, Luolin Wang and Sha Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:224
  50. Increasing attention has been paid to the effect of Epimedium on the nervous system, particularly anti-depression function. In the present study, we applied network pharmacology to introduce a testable hypothesis...

    Authors: Yankai Dong, Bo Tao, Xing Xue, Caixia Feng, Yating Ren, Hengyu Ma, Junli Zhang, Yufang Si, Sisi Zhang, Si Liu, Hui Li, Jiahao Zhou, Ge Li, Zhifei Wang, Juanping Xie and Zhongliang Zhu
    Citation: BMC Complementary Medicine and Therapies 2021 21:222