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  1. Central obesity and insulin resistance are associated with metabolic syndrome (MetS) which is aggravated by diet and sedentary lifestyle. Athrixia phylicoides (AP) is reported by rural communities to have medicin...

    Authors: Madigoahle A. M. Mokwena, Godwill Azeh Engwa, Benedicta N. Nkeh-Chungag and Constance R. Sewani-Rusike

    Citation: BMC Complementary Medicine and Therapies 2021 21:292

    Content type: Research

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  2. Insulin resistance and hormonal imbalances are key features in the pathophysiology of polycystic ovarian syndrome (PCOS). We have previously shown that Ficus deltoidea var. deltoidea Jack (Moraceae) can improve i...

    Authors: Muhammad Aliff Haslan, Nurdiana Samsulrizal, Nooraain Hashim, Noor Syaffinaz Noor Mohamad Zin, Farshad H. Shirazi and Yong Meng Goh

    Citation: BMC Complementary Medicine and Therapies 2021 21:291

    Content type: Research

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  3. Trypanosomiasis is one of the neglected tropical diseases of both humans and animals which decreases their productivity and causes death in the worst scenario. Unavailability of vaccines, the low therapeutic i...

    Authors: Ayechew Yetayeh Emiru, Eyasu Makonnen, Fikru Regassa, Fekadu Regassa and Takele Beyene Tufa

    Citation: BMC Complementary Medicine and Therapies 2021 21:290

    Content type: Research

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  4. H9N2 avian influenza viruses (AIVs) infect avian and mammalian hosts and provide internal genes for new emerging highly pathogenic avian viruses that cause severe pneumonia with high mortality, for which few m...

    Authors: Beixian Zhou, Linxin Wang, Yueyun Liang, Jing Li and Xiping Pan

    Citation: BMC Complementary Medicine and Therapies 2021 21:289

    Content type: Research

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  5. Our previous study indicated that Potentilla reptans root has a preconditioning effect by its antioxidant and anti-apoptotic effects in an isolated rat heart ischemia/reperfusion (IR) model. In the present study,...

    Authors: Ayesheh Enayati, Aref Salehi, Mostafa Alilou, Hermann Stuppner, Mirali Polshekan, Maryam Rajaei, Mona Pourabouk, Ali Jabbari, Zohreh Mazaheri, Narguess Yassa, Hamid Reza Moheimani and Vahid Khori

    Citation: BMC Complementary Medicine and Therapies 2021 21:288

    Content type: Research

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  6. Pseudomonas aeruginosa is the most common Gram-negative bacterium associated with nosocomial respiratory infections. Lavender essential oil is mainly used in aromatherapy, but it has several pharmacological and ...

    Authors: Edina Pandur, Alex Balatinácz, Giuseppe Micalizzi, Luigi Mondello, Adrienn Horváth, Katalin Sipos and Györgyi Horváth

    Citation: BMC Complementary Medicine and Therapies 2021 21:287

    Content type: Research

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  7. Oral candidiasis is an opportunistic disease caused by fungi of the Candida genus. The occurrence of Candida spp. resistance to the commercial antifungal drugs points to the search for alternative treatments. Pro...

    Authors: Ana Rita Sokolonski, Maísa Santos Fonseca, Bruna Aparecida Souza Machado, Kathleen Ramos Deegan, Roberto Paulo Correia Araújo, Marcelo Andrés Umsza-Guez, Roberto Meyer and Ricardo W. Portela

    Citation: BMC Complementary Medicine and Therapies 2021 21:286

    Content type: Research article

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  8. The results of recent surveys indicate that more than 50% of the German population has experience with complementary and alternative medicine (CAM) or uses CAM regularly. This study investigated the CAM usage ...

    Authors: Ann-Kathrin Lederer, Alexandra Baginski, Lena Raab, Stefanie Joos, Jan Valentini, Carina Klocke, Yvonne Samstag, Katrin Hübner, Ivana Andreeva, Thomas Simmet, Tatiana Syrovets, Susanne Hafner, Anna Freisinger, Maximilian Andreas Storz and Roman Huber

    Citation: BMC Complementary Medicine and Therapies 2021 21:285

    Content type: Research

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  9. Stephania yunnanensis H. S. Lo is widely used as an antipyretic, analgesic and anti-inflammatory herbal medicine in SouthWest China. In this study, we investigated the anti-inflammatory activity and mechanism of...

    Authors: Yuancui Zhao, Lili Cui, Xing Xin Yang, Xingqian Sun, Yunkuan Liu, Zixian Yang, Liyuan Zhu, Chaorui Peng, Danye Li, Junfei Cai and Yunshu Ma

    Citation: BMC Complementary Medicine and Therapies 2021 21:284

    Content type: Research

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  10. We aimed to evaluate the effect of cranberry supplementation on serum liver enzymes, hepatic steatosis, and cardiometabolic risk factors in patients with non-alcoholic fatty liver (NAFLD).

    Authors: Kourosh Masnadi Shirazi, Elham Shirinpour, Arman Masnadi Shirazi and Zeinab Nikniaz

    Citation: BMC Complementary Medicine and Therapies 2021 21:283

    Content type: Research

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  11. Mucuna pruriens (L.) has been used for the treatment of several ailments in folkloric medicine. The present study therefore investigates the hepatoprotective and nephroprotective potentials of its leaves extract...

    Authors: Temidayo Ogunmoyole, Ayomide Micheal Ola-Awe and Omotola Grace Fatile

    Citation: BMC Complementary Medicine and Therapies 2021 21:282

    Content type: Research

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  12. Palmijihwanghwan (PJH) is a traditional medicine and eight constituents derived from PJH possess anti-inflammatory activities. However, the scientific evidence for its potential as a therapeutic agent for inflam...

    Authors: Eun Bok Baek, Jin-hyung Rho, Eunhye Jung, Chang-Seob Seo, Jin-Hee Kim and Hyo-Jung Kwun

    Citation: BMC Complementary Medicine and Therapies 2021 21:281

    Content type: Research

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  13. Garcinia subelliptica Merr. is a multipurpose coastal tree, the potential medicinal effects of which have been studied, including cancer suppression. Here, we present evidence that the ethanol extract of G. subel...

    Authors: Kyun Ha Kim, Ji Yeon Lee, Wan Yi Li, Sangwoo Lee, Han-Sol Jeong, Jun-Yong Choi and Myungsoo Joo

    Citation: BMC Complementary Medicine and Therapies 2021 21:280

    Content type: Research

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  14. Obesity prevalence has increased during the past few decades, causing a pandemic with an influx in other co-morbidities. Many factors influence weight gain in an obesogenic environment therefore strategies for...

    Authors: Ranil Jayawardena, Tormalli V. Francis, Sachith Abhayaratna and Priyanga Ranasinghe

    Citation: BMC Complementary Medicine and Therapies 2021 21:279

    Content type: Research article

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  15. Henoch-Schönlein purpura nephritis (HSPN) is listed as the most common secondary glomerular diseases among children. Approximately 15 to 20% of children eventually could develop into chronic renal failure. Chi...

    Authors: Xue Xue, Xue-han Liu, Chun-li Lu, Xin-yan Jin, Qiang Liu, Xiao-qin Wang and Jian-ping Liu

    Citation: BMC Complementary Medicine and Therapies 2021 21:278

    Content type: Research article

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  16. Tuberculosis (TB) is major health concern and reason of deaths from decades to current date. Even though with a lot of advancements, diagnostic techniques, and discovery of standard antibiotics TB remains cruc...

    Authors: Chang Sun, Xiaoying Zhang, Jialu Wang, Yahao Chen and Cunren Meng

    Citation: BMC Complementary Medicine and Therapies 2021 21:277

    Content type: Research

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  17. Bauhinia strychnifolia Craib is an herb in Thai traditional medicine. Its decoction is traditionally used as an anticancer, antidiarrheal, and hangover remedy for centuries. Several studies described bioactiviti...

    Authors: Suranat Phonghanpot and Faongchat Jarintanan

    Citation: BMC Complementary Medicine and Therapies 2021 21:276

    Content type: Research

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  18. Gastroesophageal reflux disease (GERD) is associated with lower esophageal sphincter (LES) incompetence. In some patients, GERD is refractory to acid reduction therapy which is the main treatment for GERD. So ...

    Authors: Shu-Leei Tey, Chi-Ying Li, Li-Wei Lin, Li-Ching Chang, Yea-Ling Chen, Fang-Rong Chang, San-Nan Yang and Ching-Chung Tsai

    Citation: BMC Complementary Medicine and Therapies 2021 21:275

    Content type: Research article

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  19. Cyclophosphamide (CP) is one of the potent and low cost chemotherapy used in clinical setting against a variety of tumors. However, its association with nephrotoxicity limits its therapeutic use. Ocimum gratissim...

    Authors: Quadri K. Alabi, Rufus O. Akomolafe, Joseph G. Omole, Ayodeji Aturamu, Mokolade S. Ige, Oyindasola O. Kayode and Deborah Kajewole-Alabi

    Citation: BMC Complementary Medicine and Therapies 2021 21:274

    Content type: Research

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  20. Gastric cancer is one of the most leading causes of cancer death worldwide. Therefore, treatment studies have been being conducted, one of which is screening of novel agents from medicinal herbs. Elephantopus mol...

    Authors: Tran Dang Thanh Tam, Truong Thi Bich Ngoc, Nguyen Thi Hoai Nga, Nguyen Thi My Trinh, Tran Linh Thuoc and Dang Thi Phuong Thao

    Citation: BMC Complementary Medicine and Therapies 2021 21:273

    Content type: Research article

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  21. The Prinsepia utilis Royle leaves (P. utilis) is a folk herb used for benign prostatic hyperplasia (BPH) control by ethnic minorities for centuries in China with rich in resources. Our previous studies have confi...

    Authors: Ying Peng, Chongsheng Peng, Yang Wu, Chongzhi Sun and Xiaobo Li

    Citation: BMC Complementary Medicine and Therapies 2021 21:272

    Content type: Research

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  22. We previously showed that enzymatically hydrolyzed Dendropanax morbiferus H. Lév. leaf (Hy-DP) and unripe Rubus coreanus Miq. (5-uRCK) extracts exhibit potent vasodilator effects on isolated aortic rings from rat...

    Authors: Soyi Park, Ki Hoon Lee, Hakjoon Choi, Goeun Jang, Wan Seok Kang, Eun Kim, Jin Seok Kim, Chang-su Na and Sunoh Kim

    Citation: BMC Complementary Medicine and Therapies 2021 21:271

    Content type: Research article

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  23. Diabetes mellitus is a common disease effecting the lifestyles of majority world population. In this research work, we have embarked the potential role of crude extracts and isolated compounds of Notholirion thom...

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Ali O. Alqarni, Bandar A. Alyami, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Umer Rashid and Abdul Sadiq

    Citation: BMC Complementary Medicine and Therapies 2021 21:270

    Content type: Research

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  24. The present study extensively aimed to evaluate the underlying mechanism of the immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium (PLM).

    Authors: Mi-Rae Shin, Ji Hye Lee, Jin A Lee, Min Ju Kim, Hae-Jin Park, Byeong Wook Park, Seung Bo Seo and Seong-Soo Roh

    Citation: BMC Complementary Medicine and Therapies 2021 21:269

    Content type: Research article

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  25. Use of herbal medicines during pregnancy has been increase in many developing and developed countries. In spite of the studies done on herbal medicine, no study has addressed use of herbal medicine among pregn...

    Authors: Getu Tesfaw Addis, Birhanu Demeke Workneh and Mesfin Haile Kahissay

    Citation: BMC Complementary Medicine and Therapies 2021 21:268

    Content type: Research article

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  26. Alzheimer’s disease (AD) is the most common dementia worldwide, and there is still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese medicine with multiple neuroprotective...

    Authors: Xiao-feng Wang, Hong-he Xiao, Yu-tong Wu, Liang Kong, Ji-cong Chen, Jing-xian Yang and Xiao-le Hu

    Citation: BMC Complementary Medicine and Therapies 2021 21:267

    Content type: Research

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  27. Authors: Sanya Haiaty, Mohammad-Reza Rashidi, Maryam Akbarzadeh, Ahad Bazmani, Mostafa Mostafazadeh, Saba Nikanfar, Zohre Zibaei, Reza Rahbarghazi and Mohammad Nouri

    Citation: BMC Complementary Medicine and Therapies 2021 21:266

    Content type: Correction

    Published on:

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:83

  28. Oils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases ...

    Authors: Fatemeh Saghafi, Farzaneh Mirzaie, Elham Gorji, Razieh Nabimeybodi, Mehdi Fattahi, Hamed Mahmoodian and Rahele Zareshahi

    Citation: BMC Complementary Medicine and Therapies 2021 21:265

    Content type: Research

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  29. Physiotherapists (PTs) across the globe are increasingly incorporating filiform needling techniques (e.g., acupuncture, dry needling) into their clinical toolkits; and, the evidence base for these complementar...

    Authors: Nadine Ijaz, Sandy Welsh and Heather Boon

    Citation: BMC Complementary Medicine and Therapies 2021 21:264

    Content type: Research article

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  30. Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death. Traditional Chinese medicine (TCM) has special advantages in relieving HCC, while Astragalus membranaceus is commonly used in TC...

    Authors: Zhili Liu, Huihan Ma and Zelin Lai

    Citation: BMC Complementary Medicine and Therapies 2021 21:263

    Content type: Research article

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  31. Lack of information exists about the use of traditional and complementary medicine (TCM) use among middle-aged and older adults in India, which led to studying the estimates of past-12-month Ayurveda/Yoga/Natu...

    Authors: Supa Pengpid and Karl Peltzer

    Citation: BMC Complementary Medicine and Therapies 2021 21:262

    Content type: Research

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  32. Osteoarthritis (OA) is the most common form of arthritis, affecting millions of people worldwide and characterised by joint pain and inflammation. It is a complex disease involving inflammatory factors and aff...

    Authors: Sybille Brochard, Julien Pontin, Benoit Bernay, Karim Boumediene, Thierry Conrozier and Catherine Baugé

    Citation: BMC Complementary Medicine and Therapies 2021 21:261

    Content type: Research

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  33. Current therapy of chronic hepatitis C virus (HCV) with direct-acting antivirals (DAAs) has dramatically improved the sustained virologic response (SVR) of affected patients; however, treatment with DAAs remai...

    Authors: Adita Ayu Permanasari, Chie Aoki-Utsubo, Tutik Sri Wahyuni, Lidya Tumewu, Myrna Adianti, Aty Widyawaruyanti, Hak Hotta and Achmad Fuad Hafid

    Citation: BMC Complementary Medicine and Therapies 2021 21:260

    Content type: Research

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  34. According to recent evidence, psychobiotics exert beneficial effects on central nervous system-related diseases, such as mental disorders. Lactobacillus plantarum PS128 (PS128), a novel psychobiotic strain, impro...

    Authors: Hei-Jen Huang, Jie-Ling Chen, Jian-Fu Liao, Yu-Hsin Chen, Min-Wei Chieu, Ya-Yun Ke, Chih-Chieh Hsu, Ying-Chieh Tsai and Hsiu Mei Hsieh-Li

    Citation: BMC Complementary Medicine and Therapies 2021 21:259

    Content type: Research article

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  35. Buchholzia coriacea Engl. is popularly called wonderful cola due to its wide ethnomedicinal use for the treatment of various ailments. We investigated the possible cytotoxic effect of its various fractions on hu...

    Authors: Hope Onohuean, Rahmat Adetutu Adisa and Abdullateef Isiaka Alagbonsi

    Citation: BMC Complementary Medicine and Therapies 2021 21:258

    Content type: Research

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  36. Oxidative stress-induced injury during hypothermic preservation is a universal problem that delays graft function and decrease the success of organ transplantation. Tanshinone IIA (Tan IIA) was reported to exh...

    Authors: Linhao Xu, Yizhou Xu, Zhoujing Zhu, Huiquan Gu, Chaofeng Chen and Jian Chen

    Citation: BMC Complementary Medicine and Therapies 2021 21:257

    Content type: Research

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  37. Microbial resistance, diabetes mellitus, and obesity are global health care problems that have posed a serious threat to both human and environmental ecosystems. The goals of the present investigations are to ...

    Authors: Nidal Jaradat, Mohammad Qadi, Iyad Ali, Fatima Hussein, Linda Issa, Doaa Rashdan, Manal Jamoos, Re’as Najem, Abdulraziq Zarour and Mohammad Arar

    Citation: BMC Complementary Medicine and Therapies 2021 21:256

    Content type: Research

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  38. Adipose tissue is a critical regulator of lipid storage and endocrine function. Impairment of the recruitment of new adipocytes in the adipose tissue is associated with ectopic fat accumulation, diabetes and i...

    Authors: Eunbi Koh, Boram Kim and Kyungoh Choi

    Citation: BMC Complementary Medicine and Therapies 2021 21:255

    Content type: Research article

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  39. Eucalyptol is an active compound of eucalyptus essential oil and was reported to have many medical attributes including cytotoxic effect on breast cancer cells. However, it has low solubility in aqueous soluti...

    Authors: Mira Nadiah Mohd Izham, Yazmin Hussin, Nurul Fattin Che Rahim, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah and Noorjahan Banu Alitheen

    Citation: BMC Complementary Medicine and Therapies 2021 21:254

    Content type: Research article

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  40. Episiotomy is the most commonn surgical procedure in midwifery which as any other wounds can cause infection or delay in healing.

    Authors: Elmira Toomari, Sepideh Hajian, Faraz Mojab, Tayebe Omidkhah and Malihe Nasiri

    Citation: BMC Complementary Medicine and Therapies 2021 21:253

    Content type: Research article

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  41. While evidence-based practice (EBP) is widely accepted across healthcare professions, research investigating its implementation in manual therapy professions such as osteopathy is limited. The primary aim of t...

    Authors: Francesco Cerritelli, Alessio Iacopini, Matteo Galli, Oliver P. Thomson, Tobias Sundberg, Matthew J. Leach and Jon Adams

    Citation: BMC Complementary Medicine and Therapies 2021 21:252

    Content type: Research

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  42. Mild cognitive impairment (MCI) is considered an intermediate phase between normal aging and dementia. As the majority of cases of amnestic MCI (aMCI) progress to Alzheimer’s disease (AD), it is considered the...

    Authors: Hee-Yeon Shin, Ha-Ri Kim, Geon-Ho Jahng, Chul Jin, Seungwon Kwon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Chang-Nam Ko and Jung-Mi Park

    Citation: BMC Complementary Medicine and Therapies 2021 21:251

    Content type: Research article

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  43. Complementary and integrative medical procedures (CIM) play an important role in general practice (GP). Consequently, in some countries (e.g. USA, Australia) specific curricula for the integration of CIM compe...

    Authors: Jan Valentini, Carina Klocke, Corina Güthlin and Stefanie Joos

    Citation: BMC Complementary Medicine and Therapies 2021 21:250

    Content type: Research

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  44. More than 80% of the African population depend on traditional medicine as a primary healthcare. Although the African migrant community is increasing in Australia, there is no research documenting if and how Af...

    Authors: Zewdneh Shewamene, Tinashe Dune and Caroline A. Smith

    Citation: BMC Complementary Medicine and Therapies 2021 21:249

    Content type: Research

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  45. Edible oils have proven health benefits in the prevention and treatment of various disorders since the establishment of human era. This study was aimed to appraise neuropharmacological studies on the commonly ...

    Authors: Mater H. Mahnashi, Bandar A. Alyami, Yahya S. Alqahtani, Ali O. Alqarni, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Muhammad Shahid, Umer Rashid and Abdul Sadiq

    Citation: BMC Complementary Medicine and Therapies 2021 21:248

    Content type: Research article

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  46. This study aimed to investigate the prevalence of and the factors associated with the regular use of complementary therapies for Taiwanese patients with systemic lupus erythematosus (SLE).

    Authors: Ming-Chi Lu, Hui-Chin Lo, Hsiu-Hua Chang, Chia-Wen Hsu and Malcolm Koo

    Citation: BMC Complementary Medicine and Therapies 2021 21:247

    Content type: Research article

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  47. Influenza A virus (IAV) infection is a continual threat to the health of animals and humans globally. Consumption of the conventional drugs has shown several side effects and drug resistance. This study was ai...

    Authors: Parvaneh Mehrbod, Hanieh Safari, Zeinab Mollai, Fatemeh Fotouhi, Yasaman Mirfakhraei, Hanieh Entezari, Saied Goodarzi and Zahra Tofighi

    Citation: BMC Complementary Medicine and Therapies 2021 21:246

    Content type: Research article

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  48. Adaptive metabolic response towards a low oxygen environment is essential to maintain rapid tumour proliferation and progression. The vascular network that surrounds the tumour develops an intermittent hypoxic...

    Authors: S. H. Shahruzaman, F. Z. Yusof, S. Maniam, S. Fakurazi and S. Maniam

    Citation: BMC Complementary Medicine and Therapies 2021 21:245

    Content type: Research

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  49. The present study aims to investigate the knowledge, attitude, and performance of Iranian Healthcare Professionals (HP) about Complementary and Alternative Medicine (CAM) modalities.

    Authors: Alireza Jafari, Mohaddeseh Zanganeh, Zahra Kazemi, Elaheh Lael-Monfared and Hadi Tehrani

    Citation: BMC Complementary Medicine and Therapies 2021 21:244

    Content type: Research article

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  50. Quercetin and H19 can promote osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). However, whether quercetin regulates H19 expression to promote osteogenic differentiation of BMSCs is unc...

    Authors: Wei Bian, Shunqiang Xiao, Lei Yang, Jun Chen and Shifang Deng

    Citation: BMC Complementary Medicine and Therapies 2021 21:243

    Content type: Research

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