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  1. Natural products constitute a promising class of therapeutics for the treatment of gingivitis and periodontitis as well as the maintenance of oral health. However, the limited understanding behind their potent...

    Authors: Ana M. Chang, Shatha Bamashmous, Richard P. Darveau and Sunethra Rajapakse

    Citation: BMC Complementary Medicine and Therapies 2020 20:62

    Content type: Research article

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  2. Pharmacokinetic interaction is one of the most important indices for the evaluation of the compatibility of herbal medicines. Both Gancao (Glycyrrhizae Radix et Rhizoma) and Huanglian (Coptidis Rhizoma) are commo...

    Authors: Ji-Quan Zhang, Rui Wang, Ting Zhou, Qing Zhao, Chun-Cao Zhao and Bing-Liang Ma

    Citation: BMC Complementary Medicine and Therapies 2020 20:61

    Content type: Research article

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  3. Traditional medicine serves as a form of primary health care for more than 80% of African populations. Currently, there is no research documenting if and how African migrant communities engage with their tradi...

    Authors: Zewdneh Shewamene, Tinashe Dune and Caroline A. Smith

    Citation: BMC Complementary Medicine and Therapies 2020 20:60

    Content type: Research article

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  4. Naturopathy is a distinct system of traditional and complementary medicine recognized by the World Health Organization and defined by its philosophic approach to patient care, rather than the treatments used b...

    Authors: Amie Steel, Hope Foley, Ryan Bradley, Claudine Van De Venter, Iva Lloyd, Janet Schloss, Jon Wardle and Rebecca Reid

    Citation: BMC Complementary Medicine and Therapies 2020 20:59

    Content type: Research article

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  5. In response to high demand and the growing body of evidence for traditional and complementary therapies, the practice of integrative medicine and integrative healthcare has emerged where these therapies are bl...

    Authors: Carolyn Ee, Kate Templeman, Suzanne Grant, Nicole Avard, Michael de Manincor and Jennifer Hunter

    Citation: BMC Complementary Medicine and Therapies 2020 20:58

    Content type: Research article

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  6. The well-known traditional Chinese herbal formula Guizhi Fuling Wan (GFW) was recently reported to improve the curative effects of chemotherapy for ovarian cancer with few clinical side effects. The present st...

    Authors: Li Han, Xueyun Cao, Zhong Chen, Xiaojuan Guo, Lei Yang, Yubing Zhou and Hua Bian

    Citation: BMC Complementary Medicine and Therapies 2020 20:57

    Content type: Research article

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  7. Ficus deltoidea (FD) has been shown to have antidiabetic, anti-inflammatory, antinociceptive and antioxidant properties. However, its effects on key events in the pathogenesis of atherosclerosis are unknown.

    Authors: Amirah Mohd Ariff, Nurul Ain Abu Bakar, Suhaila Abd. Muid, Effat Omar, Nor Hadiani Ismail, Abdul Manaf Ali, Noor Alicezah Mohd Kasim and Hapizah Mohd Nawawi

    Citation: BMC Complementary Medicine and Therapies 2020 20:56

    Content type: Research article

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  8. Canarium patentinervium leaves are used by the local indigenous people of Malaysia for wound healing. The current study is undertaken to screen the comprehensive antibacterial activity of the leaves and barks ext...

    Authors: R. Mogana, A. Adhikari, M. N. Tzar, R. Ramliza and C. Wiart

    Citation: BMC Complementary Medicine and Therapies 2020 20:55

    Content type: Research article

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  9. Oxidative stress mediates the nerve injury during the pathogenesis of Alzheimer’s disease (AD). Protecting against oxidative stress damage is an important strategy to prevent and treat AD. Di-Huang-Yi-Zhi (DHY...

    Authors: Li-Min Zhang, Rong-Rong Zhen, Chao Gu, Tian-Li Zhang, Yue Li, Miao Jin, Bing Hu and Hong-Mei An

    Citation: BMC Complementary Medicine and Therapies 2020 20:54

    Content type: Research article

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  10. The aim of the randomized double-blinded clinical trial was to evaluate the effect of tooth brushing with Salvadora persica (miswak) sticks on Streptococcus mutans count and the mean plaque score relative to brus...

    Authors: Heba J. Sabbagh, Khalil S. AlGhamdi, Hattan T. Mujalled and Sara M. Bagher

    Citation: BMC Complementary Medicine and Therapies 2020 20:53

    Content type: Research article

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  11. This study seeks to investigate factors associated with using complementary and alternative medicine (CAM) for a mental illness among the three major ethnic groups (Chinese, Indians and Malays) in the general ...

    Authors: Vanessa Seet, Edimansyah Abdin, Janhavi A. Vaingankar, Shazana Shahwan, Sherilyn Chang, Bernard Lee, Siow Ann Chong and Mythily Subramaniam

    Citation: BMC Complementary Medicine and Therapies 2020 20:52

    Content type: Research article

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  12. The use of medicinal plants or other alternative practices can be the only therapeutic resources for many communities and ethnic groups, especially in developing countries. In Brazil, the Ministry of Health in...

    Authors: Patricia de Moraes Mello Boccolini and Cristiano Siqueira Boccolini

    Citation: BMC Complementary Medicine and Therapies 2020 20:51

    Content type: Research article

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  13. Globally, more than 170 million people are infected with hepatitis C virus, a major cause of cirrhosis and hepatocellular carcinoma. The Yinchenhao Decoction (YCHD) is a classic formula comprising three herbal...

    Authors: Jingyuan Zhang, Xinkui Liu, Jiarui Wu, Wei Zhou, Jinhui Tian, Siyu Guo, Shan Shan Jia, Ziqi Meng and Mengwei Ni

    Citation: BMC Complementary Medicine and Therapies 2020 20:50

    Content type: Research article

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  14. Inflammation is one of the key components in the initiation and progression of hepatic diseases. If not treated, inflammation may cause cell dysplasia, and ultimately cancer. In the current study, we investiga...

    Authors: Adeeb Shehzad, Shagufta Rehmat, Salman Ul-Islam, Rizwan Ahmad, Meneerah Aljafary, Noor A. Alrushaid and Ebtesam A. Al-Suhaimi

    Citation: BMC Complementary Medicine and Therapies 2020 20:49

    Content type: Research article

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  15. Radix isatidis has been used in China and other Asian countries for its antiviral and anti-inflammatory effects for thousands of years. However, the antiviral effect of Radix isatidis polysaccharide against pseud...

    Authors: Chao Tong, Zewen Chen, Fang Liu, Yanyan Qiao, Tong Chen and Xuebing Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:48

    Content type: Research article

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  16. The aim of this study was to investigate the effect of tannase-converted green tea extract with a high (−)-epicatechin (EC), (−)-epigallocatechin (EGC), and gallic acid (GA) content on myotube density and fusi...

    Authors: Ki-Bae Hong, Hee-Seok Lee, Jeong Sup Hong, Dong Hyeon Kim, Joo Myung Moon and Yooheon Park

    Citation: BMC Complementary Medicine and Therapies 2020 20:47

    Content type: Research article

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  17. Cyanidin-3-glucoside (C3G), a major anthocyanin present in berries, exhibits a strong antioxidant and has been shown to possess a neuroprotection. Prolonged exposure to glutamate will lead to oxidative damage ...

    Authors: Monruedee Sukprasansap, Pithi Chanvorachote and Tewin Tencomnao

    Citation: BMC Complementary Medicine and Therapies 2020 20:46

    Content type: Research article

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  18. Dental caries is one of the most prevalent chronic oral diseases worldwide. Dental caries is mainly associated with Streptococcus mutans and the Lactobacillus species. A specific relationship was found between ni...

    Authors: Abdulaziz M. Alshahrani and Richard L. Gregory

    Citation: BMC Complementary Medicine and Therapies 2020 20:45

    Content type: Research article

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  19. The effect of ginsenosides on the growth and apoptosis of human lens epithelial (HLE) B3 cells exposed to H2O2 was investigated. In addition, the effect of ginsenosides on gene expression in HLE-B3 cells was anal...

    Authors: Zhewen Wang, Shiping Zhou, Xiaoqing Hu and Jiannan Chai

    Citation: BMC Complementary Medicine and Therapies 2020 20:44

    Content type: Research article

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  20. Despite the large number of trials conducted using herbal oral care products for the reduction of dental plaque or gingivitis, results are conflicting and inconclusive.

    Authors: Chandrashekar Janakiram, Ramanarayanan Venkitachalam, Paul Fontelo, Timothy J. Iafolla and Bruce A. Dye

    Citation: BMC Complementary Medicine and Therapies 2020 20:43

    Content type: Research article

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  21. Qilin pills (QLPs), a classic Traditional Chinese Medicine (TCM) formula for treating male infertility, effectively improve semen quality in clinical trials. This study was designed to evaluate the effects of ...

    Authors: Kaishu Zhang, Longlong Fu, Qi An, Weihong Hu, Jianxin Liu, Xiuming Tang, Yu Ding, Wenhong Lu, Xiaowei Liang, Xuejun Shang and Yiqun Gu

    Citation: BMC Complementary Medicine and Therapies 2020 20:42

    Content type: Research article

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  22. Most randomized controlled trials (RCTs) of traditional medicine (such as traditional Chinese medicine (TCM), psychotherapy or behavioral therapy, and dietary interventions, etc.) have reported that they could...

    Authors: Qiliang Chen, Qiong Wang, Shanshan Ding, Shunan Li, Yuanyuan Zhang, Shujiao Chen, Xuejuan Lin, Candong Li and Tetsuya Asakawa

    Citation: BMC Complementary Medicine and Therapies 2020 20:41

    Content type: Research article

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  23. Guettarda speciosa is mainly found in tropical areas in Asia. Although G. speciosa is traditionally used to treat some of the inflammatory disorders, the experimental evidence supporting the anti-inflammatory eff...

    Authors: Kyun Ha Kim, Ji Yeon Lee, Seonju Ahn, Ran Won, Sang-Jun Kim, Seung-Il Jeong, Jung Ju Lee, Jong-In Kim, Jun-Yong Choi and Myungsoo Joo

    Citation: BMC Complementary Medicine and Therapies 2020 20:40

    Content type: Research article

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  24. Stroke is a major cause of death and disability worldwide. Over the years, traditional medicines for stroke treatment have undergone tremendous progress, but few bibliometric studies have been performed. This ...

    Authors: Lieyu Huang, Xuefeng Shi, Nan Zhang, Ya Gao, Qian Bai, Liming Liu, Ling Zuo and Baolin Hong

    Citation: BMC Complementary Medicine and Therapies 2020 20:39

    Content type: Research article

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  25. Qiliqiangxin (QLQX) capsule is a Traditional Chinese Medicine (TCM) that has been approved in China for the treatment of chronic heart failure (CHF). Our previous study showed with a background of standard HF ...

    Authors: Wenming Yao, Iokfai Cheang, Shengen Liao, Yanli Zhou, Fang Zhou, Dongjie Xu, Zhenhua Jia, Liping Chang, Haifeng Zhang and Xinli Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:38

    Content type: Study protocol

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  26. Yiganling (YGL) capsule is a traditional Chinese medicine preparation consisting of eight herbs that has been clinically proven to have a favorable treatment effect on Hepatitis B (HB). However, due to its mul...

    Authors: Chao Lu, Wanjin Fu, Renpeng Zhou and Wei Hu

    Citation: BMC Complementary Medicine and Therapies 2020 20:37

    Content type: Research article

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  27. Embryo implantation is essential for a successful pregnancy, and an elaborate synchronization between the receptive endometrium and trophoblast is required to achieve this implantation. To increase ‘endometria...

    Authors: Seong-Eun Kim, Joo Eun Lee, Young-Hyun Han, Se-In Lee, Do Kyung Kim, Seok-Rae Park, Seong-Lan Yu and Jaeku Kang

    Citation: BMC Complementary Medicine and Therapies 2020 20:36

    Content type: Research article

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  28. Osteoporosis is related to the number and activity of osteoclasts. The goal of the present study was to demonstrate the effect of Chaenomelis Fructus (CF) on osteoclastogenesis and its mechanism of bone loss p...

    Authors: Minsun Kim, Ho-Seok Kim, Jae-Hyun Kim, Eun-Young Kim, Bina Lee, Sung Yub Lee, Jae-Yun Jun, Min Beom Kim, Youngjoo Sohn and Hyuk-Sang Jung

    Citation: BMC Complementary Medicine and Therapies 2020 20:35

    Content type: Research article

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  29. The current work aimed to assess whether Gynostemma pentaphyllum (GP), a Chinese herbal medicine, structurally modifies the gut microbiota in rats during non-alcoholic fatty liver disease (NAFLD) treatment.

    Authors: Shu-Hua Shen, Ting-Yan Zhong, Cui Peng, Jie Fang and Bin Lv

    Citation: BMC Complementary Medicine and Therapies 2020 20:34

    Content type: Research article

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  30. Obesity is a major public health concern worldwide. A sedentary life and a nutritional transition to processed foods and high-calorie diets are contributing factors to obesity. The demand for nutraceutical foo...

    Authors: Cécile Héliès-Toussaint, Edwin Fouché, Nathalie Naud, Florence Blas-Y-Estrada, Maria del Socorro Santos-Diaz, Anne Nègre-Salvayre, Ana Paulina Barba de la Rosa and Françoise Guéraud

    Citation: BMC Complementary Medicine and Therapies 2020 20:33

    Content type: Research article

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  31. Yigan mingmu oral liquid (YGMM) is a herbal medicine based on a famous Chinese herbal formula that has been used for sore eyes for more than 400 years. Eye health is closely associated with the liver based on ...

    Authors: Qigui Mo, Gao Zhou, Baibo Xie, Bingxin Ma, Xinyu Zang, Yuxin Chen, Linyou Cheng, James Hua Zhou and Youwei Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:32

    Content type: Research article

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  32. Each year 1.5 million women experience menopause when menstrual cycles cease resulting from the loss of ovarian function and oestrogen deprivation, a hormone that helps prevent bone loss. This study investigat...

    Authors: Sasikala M. Chinnappan, Annie George, Godavarthi Ashok and Yogendra Kumar Choudhary

    Citation: BMC Complementary Medicine and Therapies 2020 20:31

    Content type: Research article

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  33. Several Host defence peptides (HDPs) are low molecular weight (< 50 amino acids residues) peptides detected in several ethnomedicinal plants and have particularly gained research interest in recent times. Due ...

    Authors: Omonike O. Ogbole, Nkiruka C. Ndabai, Toluwanimi E. Akinleye and Alfred F. Attah

    Citation: BMC Complementary Medicine and Therapies 2020 20:30

    Content type: Research article

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  34. Crocetin is a major active component of saffron, which has a wide range of pharmacological effects. However, due to its low solubility, the pharmacological effects of crocetin cannot be better utilized.

    Authors: Mao-Ze Wang, Jin Gao, Yang Chu, Jie Niu, Ming Chen, Qiang Shang, Li-Hua Peng and Zhi-Hong Jiang

    Citation: BMC Complementary Medicine and Therapies 2020 20:29

    Content type: Research article

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  35. The tanshinones and phenolic acids in Salvia miltiorrhiza (also named Danshen) have been confirmed for the treatment of coronary heart disease (CHD), but the action mechanisms remain elusive.

    Authors: Dongxue Wu, Mengqi Huo, Xi Chen, Yanling Zhang and Yanjiang Qiao

    Citation: BMC Complementary Medicine and Therapies 2020 20:28

    Content type: Research article

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  36. As a compound Chinese medicine, Zhenqing Recipe (ZQR) has been shown to ameliorate hyperglycemia, hyperlipidemia, fatty liver and insulin resistance in patients with diabetes and diabetic rats. In this paper, ...

    Authors: Daofei Song, Lei Yin, Chang Wang and Xiuying Wen

    Citation: BMC Complementary Medicine and Therapies 2020 20:27

    Content type: Research article

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  37. Ceramides play a fundamental role in maintaining the skin health as a function of improved barrier permeability. Reduced ceramide content results in skin dryness and wrinkledness. Intake of dietary ceramides p...

    Authors: Sudeep Heggar Venkataramana, Naveen Puttaswamy and Shyamprasad Kodimule

    Citation: BMC Complementary Medicine and Therapies 2020 20:26

    Content type: Research article

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  38. Candida vaginitis is a global health hazard that increases morbidity among women of childbearing age. Recent studies have revealed a high incidence of drug-resistant Candida strains. Additionally, treating Candid...

    Authors: Mohamed Taha Yassin, Ashraf Abdel-Fattah Mostafa and Abdulaziz Abdulrahman Al-Askar

    Citation: BMC Complementary Medicine and Therapies 2020 20:25

    Content type: Research article

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  39. Citrus plants particularly lemon (Citrus limon L.) concoctions are ethno-medically used for treatment of infectious diseases including malaria. Therefore, we set an experiment to investigate the effects of lemon ...

    Authors: Kelvin M. Shija, Ramadhani S. O. Nondo, Doreen Mloka, Raphael Z. Sangeda and George M. Bwire

    Citation: BMC Complementary Medicine and Therapies 2020 20:24

    Content type: Research article

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  40. Chondrocyte apoptosis activated by the mitochondrial dependent pathway serves a crucial role in cartilage degeneration of osteoarthritis (OA). In the present study, the protective effects of CMCS against sodiu...

    Authors: Bin He, Fei Wu, Xiaohai Li, Yang Liu, Li Fan and Haohuan Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:23

    Content type: Research article

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  41. Alisol A-24-acetate (AA-24-a) is one of the main active triterpenes isolated from the well-known medicinal plant Alisma orientale (Sam.) Juz., which possesses multiple biological activities, including a hypoglyce...

    Authors: Jia-xiang Chen, Hai-yan Li, Tian-tian Li, Wen-cheng Fu, Xin Du, Chun-hui Liu and Wen Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:22

    Content type: Research article

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  42. Germacrone is one of the natural bioactive compounds found in Rhizoma curcuma essential oils. In this study, the potential anti-cancer effect of germacrone in gastric cancer cell line BGC823 was investigated.

    Authors: Lei Wu, Lifen Wang, Xiangguo Tian, Junyong Zhang and Hua Feng

    Citation: BMC Complementary Medicine and Therapies 2020 20:21

    Content type: Research article

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  43. Danshensu is an active constituent in the extracts of Danshen which is a traditional Chinese medical herb. Rotenone inhibits complex I of the mitochondrial electron transport chain in dopaminergic neurons lead...

    Authors: Tian Wang, Cuiting Li, Bing Han, Zhenhua Wang, Xiaoyu Meng, Leiming Zhang, Jie He and Fenghua Fu

    Citation: BMC Complementary Medicine and Therapies 2020 20:20

    Content type: Research article

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  44. In Mozambique, bacterial and parasitic diseases contribute to a high burden of mortality and morbidity. These infectious diseases are treated with antibiotics, antihelmintic or antiparasitic drugs. However, mi...

    Authors: Filomena Barbosa, Delfina Hlashwayo, Victor Sevastyanov, Valeriano Chichava, Adilência Mataveia, Ernesto Boane and Aida Cala

    Citation: BMC Complementary Medicine and Therapies 2020 20:19

    Content type: Research article

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  45. Among women suffering from urinary incontinence (UI), about one-third are diagnosed with mixed urinary incontinence (MUI), among which urgency-predominant MUI causes more shame and inconvenience to patients. T...

    Authors: Yuanjie Sun, Yan Liu, Tongsheng Su, Jianhua Sun, Ying Wu and Zhishun Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:18

    Content type: Study protocol

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  46. The use of herbal medicine is on the rise worldwide, and safety issues associated with herbal medicines may have an exacerbated impact in elderly because this population has an increased susceptibility and sen...

    Authors: Carolina Miranda de Sousa Lima, Mayara Amoras Teles Fujishima, Bruno de Paula Lima, Patrícia Carvalho Mastroianni, Francisco Fábio Oliveira de Sousa and Jocivânia Oliveira da Silva

    Citation: BMC Complementary Medicine and Therapies 2020 20:17

    Content type: Research article

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  47. Quantitation analysis and chromatographic fingerprint of multi-components are frequently used to evaluate quality of herbal medicines but fail to reveal activity of the components. It is necessary to develop a...

    Authors: Hong-Ying Li, Jiang-Ji Fang, Hua-Dan Shen, Xue-Qiong Zhang, Xiao-Ping Ding and Jun-Feng Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:16

    Content type: Research article

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  48. Gastrointestinal cancer is one of the most common malignancies and imposes heavy burdens on both individual health and social economy. We sought to survey the effect of a self-care education program on quality...

    Authors: Jun Xie, Tingli Zhu, Qun Lu, Xiaomin Xu, Yinghua Cai and Zhenghong Xu

    Citation: BMC Complementary Medicine and Therapies 2020 20:15

    Content type: Research article

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  49. Euphorbia hirta (Linn) family Euphorbiaceae has been used in indigenous system of medicine for the treatment of gastrointestinal disorders. This study was designed to determine the pharmacological basis for the m...

    Authors: Muhammad Zeeshan Ali, Malik Hassan Mehmood, Muhammad Saleem and Anwarul-Hassan Gilani

    Citation: BMC Complementary Medicine and Therapies 2020 20:14

    Content type: Research article

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  50. The proliferation and resistance of microorganisms area serious threat against humankind and the search for new therapeutics is needed. The present report describes the antiplasmodial and anticancer activities...

    Authors: Romeol Romain Koagne, Frederick Annang, Bastien Cautain, Jesús Martín, Guiomar Pérez-Moreno, Gabin Thierry M. Bitchagno, Dolores González-Pacanowska, Francisca Vicente, Ingrid Konga Simo, Fernando Reyes and Pierre Tane

    Citation: BMC Complementary Medicine and Therapies 2020 20:8

    Content type: Research article

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