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  1. Plant species from the genus Tecoma are found in tropical and subtropical regions around the world. Some of them are grown as ornamental plants and others can be used as medicinal plants. In the present study, et...

    Authors: Adriana Cotta Cardoso Reis, Breno Mello Silva, Hélia Maria Marques de Moura, Guilherme Rocha Pereira and Geraldo Célio Brandão

    Citation: BMC Complementary Medicine and Therapies 2020 20:246

    Content type: Research article

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  2. At present, ursodeoxycholic acid (UDCA) is internationally recognized as a therapeutic drug in clinic. However, about 40% Primary Biliary Cholangitis (PBC) patients are poor responders to UDCA. It has been dem...

    Authors: Hui Yang, Hang Yang, Lixia Wang, Honggang Shi, Bojia Liu, Xue Lin, Qingyong Chang, Jiande D. Z. Chen and Zhijun Duan

    Citation: BMC Complementary Medicine and Therapies 2020 20:242

    Content type: Research article

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  3. The use of Chinese herbal medicine (CHM) has been widely promoted as a natural and safe way to treat illness during pregnancy. However, prescription patterns and factors influencing its use are largely unknown...

    Authors: Shu-Hui Wen, Wei-Chuan Chang, Hsuan-Shu Shen and Hsien-Chang Wu

    Citation: BMC Complementary Medicine and Therapies 2020 20:240

    Content type: Research article

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  4. Immunomodulatory effects of Tinospora crispa have been investigated due to its traditional use to treat several inflammatory disorders associated to the immune system. The present study reports the underlying mec...

    Authors: Md. Areeful Haque, Ibrahim Jantan, Hemavathy Harikrishnan and Waqas Ahmad

    Citation: BMC Complementary Medicine and Therapies 2020 20:245

    Content type: Research article

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  5. Stroke is one of the major causes of death and disability. The treatments that are provided to patients during hospitalization after an acute stroke are very important in stabilizing their medical condition an...

    Authors: Wei-Sen Chen, Hung-Chih Hsu, Yi-Wen Chuang, Meng Lee, Kuan-Yu Lu, Yi-Fei Chen and Chien-Min Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:244

    Content type: Research article

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  6. Lung cancer has the highest morbidity and mortality in the world and novel treatment strategies are still needed. Haimufang decoction (HMF) is a patented clinical prescription of traditional Chinese medicine f...

    Authors: Wei-Ping Ma, Shu-Man Hu, Yan-Lai Xu, Hai-Hua Li, Xiao-Qing Ma, Bao-Hong Wei, Fu-Yu Li, Hua-Shi Guan, Guang-Li Yu, Ming Liu and Hong-Bing Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:243

    Content type: Research article

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  7. Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of...

    Authors: Yasaman Taheri, Hafiz Ansar Rasul Suleria, Natália Martins, Oksana Sytar, Ahmet Beyatli, Balakyz Yeskaliyeva, Gulnaz Seitimova, Bahare Salehi, Prabhakar Semwal, Sakshi Painuli, Anuj Kumar, Elena Azzini, Miquel Martorell, William N. Setzer, Alfred Maroyi and Javad Sharifi-Rad

    Citation: BMC Complementary Medicine and Therapies 2020 20:241

    Content type: Review

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  8. While there are several existing eHealth technologies for drug-drug interactions and stand-alone drug adverse effects, it appears that considerably less attention is focussed on that of complementary and alter...

    Authors: Jeremy Y. Ng, Maryam Mooghali and Vanessa Munford

    Citation: BMC Complementary Medicine and Therapies 2020 20:239

    Content type: Research article

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  9. The current antimicrobial therapy is still important for the treatment of pneumonia due to MRSA infection, but there are some limitations, including the route of administration, side effect profile, and increa...

    Authors: Ryong Kong, Young-Seob Lee, Dam-Hee Kang, Shu Wang, Qianqian Li, Dong-Yeul Kwon and Ok-Hwa Kang

    Citation: BMC Complementary Medicine and Therapies 2020 20:238

    Content type: Research article

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  10. Analgesic, anti-inflammatory, and sedative drugs are available with potential side effects such as peptic ulcer and addiction among other things. In this regard, research is underway to find safe, effective, a...

    Authors: Abdur Rauf, Tareq Abu-Izneid, Fahad A. Alhumaydhi, Naveed Muhammad, Abdullah S. M. Aljohani, Saima Naz, Saud Bawazeer, Abdul Wadood and Mohammad S. Mubarak

    Citation: BMC Complementary Medicine and Therapies 2020 20:237

    Content type: Research article

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  11. Bee pollen (BP) has been used as a traditional medicine and food diet additive due to its nutritional and biological properties. The potential biological properties of bee pollen vary greatly with the botanica...

    Authors: Yuchi Zou, Jian Hu, Wenting Huang, Liyun Zhu, Mingjie Shao, Confidence Dordoe, Young-Joon Ahn, Dongxue Wang, Yeli Zhao, Ye Xiong and Xue Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:236

    Content type: Research article

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  12. Curcumin can inhibit the osteoclastogenesis and the migration of several cells including macrophages. Osteoclast precursors (OCPs) are known to exist as bone marrow-derived macrophages (BMMs). This study aims ...

    Authors: Zhengeng Liang, Yan Xue, Tao Wang, Qi Xie, Jiafu Lin and Yu Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:234

    Content type: Research article

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  13. Urinary tract infections (UTIs) caused by opportunistic pathogens are among the leading health challenges globally. Most available treatment options are failing as a result of antibiotic resistance and adverse...

    Authors: Aitebiremen G. Omokhua-Uyi, Muna A. Abdalla, Carmen M. Leonard, Abimbola Aro, Osariyekemwen O. Uyi, Johannes Van Staden and Lyndy J. McGaw

    Citation: BMC Complementary Medicine and Therapies 2020 20:233

    Content type: Research article

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  14. Field cricket (Gryllus bimaculatus) is newly emerged as an edible insect in several countries. Anti-inflammatory effect of glycosaminoglycan derived from this cricket on chronic disease animal model such as diabe...

    Authors: Mi Young Ahn, Ban Ji Kim, Ha Jeong Kim, Jang Mi Jin, Hyung Joo Yoon, Jae Sam Hwang and Byung Mu Lee

    Citation: BMC Complementary Medicine and Therapies 2020 20:232

    Content type: Research article

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  15. There is a lack of data on the use of complementary and alternative medicine (CAM) in patients with coronary heart disease (CHD). This study examined the use of CAM among patients with CHD, the reasons and fac...

    Authors: Abdelraouf O. Salah, Ahmad D. Salameh, Mohanad A. Bitar, Sa’ed H. Zyoud, Abdulsalam S. Alkaiyat and Samah W. Al-Jabi

    Citation: BMC Complementary Medicine and Therapies 2020 20:231

    Content type: Research article

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  16. The human placenta (HP) is a complex organ used to alleviate tiredness and promote wound healing. Previous research showed the hair growth-promoting effect of HP. However, no reports have addressed the effects...

    Authors: Mi Hye Kim, Kyuseok Kim, Haesu Lee and Woong Mo Yang

    Citation: BMC Complementary Medicine and Therapies 2020 20:230

    Content type: Research article

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  17. Thyroid-associated ophthalmopathy (TAO) is an autoimmune inflammatory disorder, which lacks effective treatment currently. Spica Prunellae (SP) is popularly used for its anti-inflammatory and immune-regulating...

    Authors: Yuhan Zhang, Xianzhi Li, Congcong Guo, Jianjun Dong and Lin Liao

    Citation: BMC Complementary Medicine and Therapies 2020 20:229

    Content type: Research article

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  18. Hyssopus cuspidatus Boriss has been used as an important ethnomedicinal plant for long to eliminate phlegm, relieve cough and as well as having antibacterial, antioxygenation, and antitumor activities. In this st...

    Authors: Lu Zhao, Zhihong Ji, Keao Li, Bo Wang, Ya Zeng and Shuge Tian

    Citation: BMC Complementary Medicine and Therapies 2020 20:228

    Content type: Research article

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  19. The roots of Pueraria lobata and Scutellaria baicalensis, herbal medicines with a long history of widespread use, have been traditionally prescribed in combination to treat stroke, diabetes, and acute infectious ...

    Authors: Jungbin Song, Young-Sik Kim, Donghun Lee and Hocheol Kim

    Citation: BMC Complementary Medicine and Therapies 2020 20:226

    Content type: Research article

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  20. Osteoarthritis (OA) is the commonest form of inflammatory joint disease. Unfortunately, to date, there is no appropriate treatment for OA. Boswellia serrata was considered as a potent anti-inflammatory, anti-arth...

    Authors: Ganpeng Yu, Wang Xiang, Tianqing Zhang, Liuting Zeng, Kailin Yang and Jun Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:225

    Content type: Research article

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  21. Overactive bladder is defined as “urgency, with or without urge incontinence, usually with frequency and nocturia”. Electroacupuncture may be a safe and an effective alternative therapy for overactive bladder,...

    Authors: Qian Wen, Ning Li, Xueling Wang, Hao Li, Fengwei Tian, Weiwei Chen, Yanyan Lu and Zhishun Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:224

    Content type: Study protocol

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  22. Integrative medicine (IM), which is the integration of complementary and alternative medicine (CAM) into conventional health services, has been applied in some nations. Despite its highly relevant holistic app...

    Authors: Andrian Liem

    Citation: BMC Complementary Medicine and Therapies 2020 20:223

    Content type: Research article

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  23. Statins are considered as standard drugs to control cholesterol levels, but their use is also associated with renal hypertrophy, hemorrhagic stroke, hepatomegaly, and myopathy. Murraya koenigii is an herb that is...

    Authors: Gul Ambreen, Afshan Siddiq, Kashif Hussain, Abdul Saboor Hussain and Zara Naz

    Citation: BMC Complementary Medicine and Therapies 2020 20:222

    Content type: Research article

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  24. Liver cirrhosis is one of the main causes of the morbidity and mortality in liver diseases. Chinese herbal medicine (CHM) has long been used for the clinical treatment of liver diseases. This study was designe...

    Authors: Fuu-Jen Tsai, Pei-Yuu Yang, Chao-Jung Chen, Ju-Pi Li, Te-Mao Li, Jian-Shiun Chiou, Chi-Fung Cheng, Po-Heng Chuang, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Bo Ban, Wen-Miin Liang and Ying-Ju Lin

    Citation: BMC Complementary Medicine and Therapies 2020 20:221

    Content type: Research article

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  25. The present study aimed to assess the perturbation in circular RNA (circRNA)/mRNA expression profiles and a circRNA-miRNA-mRNA coexpression network involved in the potential protective effect of diosgenin (DIO...

    Authors: Zhiguo Zhang, Lifeng Yue, Yuhan Wang, Yanhua Jiang, Lihua Xiang, Yin Cheng, Dahong Ju and Yanjing Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:220

    Content type: Research article

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  26. The use of complementary and alternative medicine (CAM) among type 2 diabetes mellitus (T2DM) patients is increasing worldwide. It can affect optimum glycemic management. This study was to determine the rate a...

    Authors: Md. Abdur Rafi, Dewan Tasnia Azad, Mridula Bhattacharjee, Nikita Rahman, Kazi Abdul Mubin, Md. Ajijur Rahman and Md. Golam Hossain

    Citation: BMC Complementary Medicine and Therapies 2020 20:219

    Content type: Research article

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  27. Pulmonary artery hypertension (PAH) is a vascular disease in the lung characterized by elevated pulmonary arterial pressure (PAP). Many miRNAs play a role in the pathophysiology of PAH. Perillyle alcohol (PA) ...

    Authors: Soodeh Rajabi, Hamid Najafipour, Saeideh Jafarinejad Farsangi, Siyavash Joukar, Ahmad Beik, Maryam Iranpour and Zeinab Kordestani

    Citation: BMC Complementary Medicine and Therapies 2020 20:218

    Content type: Research article

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  28. Abnormal renal metabolism is closely related to the development of chronic kidney disease. It is well known that renal inflammation plays an important role in the occurrence and development of tubulointerstiti...

    Authors: Jiao-xia Wu, An Jia, Yin-feng Tan, Han Xu, Jian-ping Tian, Yan Wang, Hai Long Li, Bing-miao Gao and Yong-hui Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:217

    Content type: Research article

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  29. The use of Complementary and Alternative Medicine (CAM) among Type 2 Diabetes Mellitus (T2DM) patients is increasing to manage the complexities of their condition, enhance their health, and ease complications....

    Authors: Hadia Radwan, Hayder Hasan, Rena Hamadeh, Mona Hashim, Zeenat AbdulWahid, Mahboobeh Hassanzadeh Gerashi, Marwa Al Hilali and Farah Naja

    Citation: BMC Complementary Medicine and Therapies 2020 20:216

    Content type: Research article

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  30. Viscum album L. (Santalaceae), commonly known as mistletoe, is a hemiparasitic plant traditionally used in complementary cancer treatment. Its antitumor potential is mostly attributed to the presence of aqueous s...

    Authors: Carla Holandino, Michelle Nonato de Oliveira Melo, Adriana Passos Oliveira, João Vitor da Costa Batista, Marcia Alves Marques Capella, Rafael Garrett, Mirio Grazi, Hartmut Ramm, Claudia Dalla Torre, Gerhard Schaller, Konrad Urech, Ulrike Weissenstein and Stephan Baumgartner

    Citation: BMC Complementary Medicine and Therapies 2020 20:215

    Content type: Research article

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  31. C-Myc overexpression is associated with poor prognosis and aggressive progression of natural killer/T-cell lymphoma (NKTCL). Matrine, a main alkaloid of the traditional Chinese herb Sophora flavescens Ait, has be...

    Authors: Jianyou Gu, Yu Zhang, Xiao Wang, Jingjing Xiang, Shu Deng, Dijiong Wu, Junfa Chen, Lihong Yu, Yan Zhou, Yaokun Wang and Jianping Shen

    Citation: BMC Complementary Medicine and Therapies 2020 20:214

    Content type: Research article

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  32. Attitudes and beliefs about massage therapy have been explored among health professionals and health profession students, but not for undergraduate preprofessional health sciences students.

    Authors: Niki Munk, Abby Church, Donya Nemati, Samantha Zabel and Amber R. Comer

    Citation: BMC Complementary Medicine and Therapies 2020 20:213

    Content type: Research article

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  33. Traditional medicines are the main source of treatment of helminthiasis in endemic areas of Togo. The present study aimed to investigate the plants used by Traditional healers (THs) to treat helminth infection...

    Authors: Essoham Ataba, Gnatoulma Katawa, Manuel Ritter, Adjoa Holali Ameyapoh, Kokou Anani, Oukoe M. Amessoudji, Pélagie Edlom Tchadié, Tchadjabo Tchacondo, Komlan Batawila, Yaovi Ameyapoh, Achim Hoerauf, Laura E. Layland and Simplice D. Karou

    Citation: BMC Complementary Medicine and Therapies 2020 20:212

    Content type: Research article

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  34. Allium hookeri is widely consumed as a vegetable and herbal medicine in Asia. A. hookeri has been reported anti-inflammatory, anti-obesity, osteoblastic, anti-oxidant, and anti-diabetic effects in animal studies....

    Authors: Soo-Hyun Park, Ui-Jin Bae, Eun-Kyung Choi, Su-Jin Jung, Sung-Hyen Lee, Jae-Heon Yang, You-Suk Kim, Do-Youn Jeong, Hyun-Ju Kim, Byung-Hyun Park and Soo-Wan Chae

    Citation: BMC Complementary Medicine and Therapies 2020 20:211

    Content type: Research article

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  35. Rheumatoid arthritis (RA) is a common inflammatory disease with a substantial burden for society and economic worldwide. Chinese patent medicines (CPMs) have gained attention as alternative remedies due to the...

    Authors: Dan Zhang, Jin-tao Lyu, Bing Zhang, Xiao-meng Zhang, Hao Jiang and Zhi-jian Lin

    Citation: BMC Complementary Medicine and Therapies 2020 20:210

    Content type: Research article

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  36. The compound 3,3′,4′,5,5′,7-hexahydroxyflavone (myricetin) is a natural flavonoid with antitumour activity. Most of the studies on myricetin have focused on the induction of tumour cell apoptosis, and little i...

    Authors: Ming-liang Zhu, Pei-min Zhang, Min Jiang, Shu-wen Yu and Lu Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:209

    Content type: Research article

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  37. Xianlinggubao formula (XLGB), a Chinese State Food and Drug Administration-permitted traditional Chinese herbal medicine, has been extensively used to treat osteoporosis. Although XLGB was shown to improve bon...

    Authors: Hangsheng Bao, Huizhi Guo, Zongquan Feng and Xin Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:208

    Content type: Research article

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  38. Depression has rapidly progressed worldwide, and the need for an efficient treatment with low side effect has risen. Melissa officinalis L and Lavandula angustifolia Mill have been traditionally used in Asia for ...

    Authors: Mostafa Araj-Khodaei, Ahmad Ali Noorbala, Reza Yarani, Fatemeh Emadi, Elham Emaratkar, Soghrat Faghihzadeh, Zahra Parsian, Fatemeh Alijaniha, Mohammad Kamalinejad and Mohsen Naseri

    Citation: BMC Complementary Medicine and Therapies 2020 20:207

    Content type: Research article

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  39. Semen Ziziphi spinosae and Radix Polygalae, two herbs commonly used together in Traditional Chinese Medicine for the treatment of insomnia and anxiety. The study aims to study the sedative-hypnotic effect of t...

    Authors: Hong Luo, Sheng-jie Sun, Yan Wang and Ying-li Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:206

    Content type: Research article

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  40. Difference of perspective between patients and physicians over integrative medicine (IM) research and service provision remains unclear despite significant use worldwide. We observed an exceptionally low utili...

    Authors: Kam Wa Chan, Pak Wing Lee, Crystal Pui Sha Leung, Gary Chi Wang Chan, Wai Han Yiu, Hoi Man Cheung, Bin Li, Sarah Wing Yan Lok, Hongyu Li, Rui Xue, Loretta Yuk Yee Chan, Joseph Chi Kam Leung, Tai Pong Lam, Kar Neng Lai and Sydney Chi Wai Tang

    Citation: BMC Complementary Medicine and Therapies 2020 20:205

    Content type: Research article

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  41. Omega-3 and acetylsalicylic acid (ASA) are two widely used “over-the-counter” drugs. Previous research has shown multiple electrode aggregometry (MEA) can detect ASA and varying Omega-3 platelet inhibiting eff...

    Authors: Harald Bagger, Mattias Hansson, Thomas Kander and Ulf Schött

    Citation: BMC Complementary Medicine and Therapies 2020 20:204

    Content type: Research article

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  42. Qiliqiangxin (QLQX) is a preparation refined from a traditional Chinese medicine compound. It plays an important role in protecting cardiac function after myocardial infarction (MI). However, the underline mec...

    Authors: Junyang Zhou, Zhixiao Wang, Yun He, Xinxia Luo, Wenjun Zhang, Li Yu, Xiuying Chen, Xiju He, Yahong Yuan, Xiaoli Wang, Xinrong Guo, Junming Tang, Mingan Zhu, Dongsheng Li and Yan Ding

    Citation: BMC Complementary Medicine and Therapies 2020 20:203

    Content type: Research article

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  43. Phyllanthus amarus has been shown to attenuate lipopolysaccharide (LPS)-induced peripheral inflammation but similar studies in the central nervous system are scarce. The aim of the present study was to investigat...

    Authors: Elysha Nur Ismail, Ibrahim Jantan, Sharmili Vidyadaran, Jamia Azdina Jamal and Norazrina Azmi

    Citation: BMC Complementary Medicine and Therapies 2020 20:202

    Content type: Research article

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  44. Diarrhoea has been the major cause of death especially in children of developing countries. Brucea antidysenterica is one of the several medicinal plants used traditionally for the treatment of diarrhoea in Ethio...

    Authors: Kaleab Alemayehu Zewdie, Dayananda Bhoumik, Dawit Zewdu Wondafrash and Kald Beshir Tuem

    Citation: BMC Complementary Medicine and Therapies 2020 20:201

    Content type: Research article

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  45. Eucalyptus essential oils have been used in traditional medicine for centuries. It was reported that Eucalyptus leaves possess antioxidant and antimicrobial effects. Here, we investigated the anti-inflammatory ac...

    Authors: Chen-Lung Ho, Lan-Hui Li, Yueh-Chun Weng, Kuo-Feng Hua and Tz-Chuen Ju

    Citation: BMC Complementary Medicine and Therapies 2020 20:200

    Content type: Research article

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  46. The network pharmacology method was used to predict the active components of Banxia Xiexin decoction, its targets and the key signalling pathways that are activated in the treatment of depression and ulcerativ...

    Authors: Ying Yu, Gong Zhang, Tao Han and Hailiang Huang

    Citation: BMC Complementary Medicine and Therapies 2020 20:199

    Content type: Research article

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  47. Flap Endonuclease 1(FEN1) has been considered as a new tumor marker in recent years and Jianpi Yangwei Decoction (JPYW) is a basic Traditional Chinese Medicine (TCM) for the treatment of gastric cancer. This s...

    Authors: Wenjie Huang, Huijuan Tang, Fang Wen, Xiaona Lu, Qingpei Li and Peng Shu

    Citation: BMC Complementary Medicine and Therapies 2020 20:196

    Content type: Research article

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  48. Zheng Qing Feng Tong Ning (ZQFTN) is a sinomenine (SIN) preparation that has been used in clinical practice. Our study aimed to assess the methodological and reporting quality of meta-analyses on the Chinese h...

    Authors: Mingge Liang, Lan Yan, Zhigang Mei, Yanan Luo, Xiaoqiang Hou and Zhitao Feng

    Citation: BMC Complementary Medicine and Therapies 2020 20:195

    Content type: Research article

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