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  1. Guettarda speciosa is mainly found in tropical areas in Asia. Although G. speciosa is traditionally used to treat some of the inflammatory disorders, the experimental evidence supporting the anti-inflammatory eff...

    Authors: Kyun Ha Kim, Ji Yeon Lee, Seonju Ahn, Ran Won, Sang-Jun Kim, Seung-Il Jeong, Jung Ju Lee, Jong-In Kim, Jun-Yong Choi and Myungsoo Joo
    Citation: BMC Complementary Medicine and Therapies 2020 20:40
  2. Stroke is a major cause of death and disability worldwide. Over the years, traditional medicines for stroke treatment have undergone tremendous progress, but few bibliometric studies have been performed. This ...

    Authors: Lieyu Huang, Xuefeng Shi, Nan Zhang, Ya Gao, Qian Bai, Liming Liu, Ling Zuo and Baolin Hong
    Citation: BMC Complementary Medicine and Therapies 2020 20:39
  3. Qiliqiangxin (QLQX) capsule is a Traditional Chinese Medicine (TCM) that has been approved in China for the treatment of chronic heart failure (CHF). Our previous study showed with a background of standard HF ...

    Authors: Wenming Yao, Iokfai Cheang, Shengen Liao, Yanli Zhou, Fang Zhou, Dongjie Xu, Zhenhua Jia, Liping Chang, Haifeng Zhang and Xinli Li
    Citation: BMC Complementary Medicine and Therapies 2020 20:38
  4. Yiganling (YGL) capsule is a traditional Chinese medicine preparation consisting of eight herbs that has been clinically proven to have a favorable treatment effect on Hepatitis B (HB). However, due to its mul...

    Authors: Chao Lu, Wanjin Fu, Renpeng Zhou and Wei Hu
    Citation: BMC Complementary Medicine and Therapies 2020 20:37
  5. Embryo implantation is essential for a successful pregnancy, and an elaborate synchronization between the receptive endometrium and trophoblast is required to achieve this implantation. To increase ‘endometria...

    Authors: Seong-Eun Kim, Joo Eun Lee, Young-Hyun Han, Se-In Lee, Do Kyung Kim, Seok-Rae Park, Seong-Lan Yu and Jaeku Kang
    Citation: BMC Complementary Medicine and Therapies 2020 20:36
  6. Osteoporosis is related to the number and activity of osteoclasts. The goal of the present study was to demonstrate the effect of Chaenomelis Fructus (CF) on osteoclastogenesis and its mechanism of bone loss p...

    Authors: Minsun Kim, Ho-Seok Kim, Jae-Hyun Kim, Eun-Young Kim, Bina Lee, Sung Yub Lee, Jae-Yun Jun, Min Beom Kim, Youngjoo Sohn and Hyuk-Sang Jung
    Citation: BMC Complementary Medicine and Therapies 2020 20:35
  7. The current work aimed to assess whether Gynostemma pentaphyllum (GP), a Chinese herbal medicine, structurally modifies the gut microbiota in rats during non-alcoholic fatty liver disease (NAFLD) treatment.

    Authors: Shu-Hua Shen, Ting-Yan Zhong, Cui Peng, Jie Fang and Bin Lv
    Citation: BMC Complementary Medicine and Therapies 2020 20:34
  8. Obesity is a major public health concern worldwide. A sedentary life and a nutritional transition to processed foods and high-calorie diets are contributing factors to obesity. The demand for nutraceutical foo...

    Authors: Cécile Héliès-Toussaint, Edwin Fouché, Nathalie Naud, Florence Blas-Y-Estrada, Maria del Socorro Santos-Diaz, Anne Nègre-Salvayre, Ana Paulina Barba de la Rosa and Françoise Guéraud
    Citation: BMC Complementary Medicine and Therapies 2020 20:33
  9. Yigan mingmu oral liquid (YGMM) is a herbal medicine based on a famous Chinese herbal formula that has been used for sore eyes for more than 400 years. Eye health is closely associated with the liver based on ...

    Authors: Qigui Mo, Gao Zhou, Baibo Xie, Bingxin Ma, Xinyu Zang, Yuxin Chen, Linyou Cheng, James Hua Zhou and Youwei Wang
    Citation: BMC Complementary Medicine and Therapies 2020 20:32
  10. Each year 1.5 million women experience menopause when menstrual cycles cease resulting from the loss of ovarian function and oestrogen deprivation, a hormone that helps prevent bone loss. This study investigat...

    Authors: Sasikala M. Chinnappan, Annie George, Godavarthi Ashok and Yogendra Kumar Choudhary
    Citation: BMC Complementary Medicine and Therapies 2020 20:31
  11. Several Host defence peptides (HDPs) are low molecular weight (< 50 amino acids residues) peptides detected in several ethnomedicinal plants and have particularly gained research interest in recent times. Due ...

    Authors: Omonike O. Ogbole, Nkiruka C. Ndabai, Toluwanimi E. Akinleye and Alfred F. Attah
    Citation: BMC Complementary Medicine and Therapies 2020 20:30
  12. Crocetin is a major active component of saffron, which has a wide range of pharmacological effects. However, due to its low solubility, the pharmacological effects of crocetin cannot be better utilized.

    Authors: Mao-Ze Wang, Jin Gao, Yang Chu, Jie Niu, Ming Chen, Qiang Shang, Li-Hua Peng and Zhi-Hong Jiang
    Citation: BMC Complementary Medicine and Therapies 2020 20:29
  13. The tanshinones and phenolic acids in Salvia miltiorrhiza (also named Danshen) have been confirmed for the treatment of coronary heart disease (CHD), but the action mechanisms remain elusive.

    Authors: Dongxue Wu, Mengqi Huo, Xi Chen, Yanling Zhang and Yanjiang Qiao
    Citation: BMC Complementary Medicine and Therapies 2020 20:28
  14. As a compound Chinese medicine, Zhenqing Recipe (ZQR) has been shown to ameliorate hyperglycemia, hyperlipidemia, fatty liver and insulin resistance in patients with diabetes and diabetic rats. In this paper, ...

    Authors: Daofei Song, Lei Yin, Chang Wang and Xiuying Wen
    Citation: BMC Complementary Medicine and Therapies 2020 20:27
  15. Ceramides play a fundamental role in maintaining the skin health as a function of improved barrier permeability. Reduced ceramide content results in skin dryness and wrinkledness. Intake of dietary ceramides p...

    Authors: Sudeep Heggar Venkataramana, Naveen Puttaswamy and Shyamprasad Kodimule
    Citation: BMC Complementary Medicine and Therapies 2020 20:26
  16. Candida vaginitis is a global health hazard that increases morbidity among women of childbearing age. Recent studies have revealed a high incidence of drug-resistant Candida strains. Additionally, treating Candid...

    Authors: Mohamed Taha Yassin, Ashraf Abdel-Fattah Mostafa and Abdulaziz Abdulrahman Al-Askar
    Citation: BMC Complementary Medicine and Therapies 2020 20:25
  17. Citrus plants particularly lemon (Citrus limon L.) concoctions are ethno-medically used for treatment of infectious diseases including malaria. Therefore, we set an experiment to investigate the effects of lemon ...

    Authors: Kelvin M. Shija, Ramadhani S. O. Nondo, Doreen Mloka, Raphael Z. Sangeda and George M. Bwire
    Citation: BMC Complementary Medicine and Therapies 2020 20:24
  18. Chondrocyte apoptosis activated by the mitochondrial dependent pathway serves a crucial role in cartilage degeneration of osteoarthritis (OA). In the present study, the protective effects of CMCS against sodiu...

    Authors: Bin He, Fei Wu, Xiaohai Li, Yang Liu, Li Fan and Haohuan Li
    Citation: BMC Complementary Medicine and Therapies 2020 20:23
  19. Alisol A-24-acetate (AA-24-a) is one of the main active triterpenes isolated from the well-known medicinal plant Alisma orientale (Sam.) Juz., which possesses multiple biological activities, including a hypoglyce...

    Authors: Jia-xiang Chen, Hai-yan Li, Tian-tian Li, Wen-cheng Fu, Xin Du, Chun-hui Liu and Wen Zhang
    Citation: BMC Complementary Medicine and Therapies 2020 20:22
  20. Germacrone is one of the natural bioactive compounds found in Rhizoma curcuma essential oils. In this study, the potential anti-cancer effect of germacrone in gastric cancer cell line BGC823 was investigated.

    Authors: Lei Wu, Lifen Wang, Xiangguo Tian, Junyong Zhang and Hua Feng
    Citation: BMC Complementary Medicine and Therapies 2020 20:21
  21. Danshensu is an active constituent in the extracts of Danshen which is a traditional Chinese medical herb. Rotenone inhibits complex I of the mitochondrial electron transport chain in dopaminergic neurons lead...

    Authors: Tian Wang, Cuiting Li, Bing Han, Zhenhua Wang, Xiaoyu Meng, Leiming Zhang, Jie He and Fenghua Fu
    Citation: BMC Complementary Medicine and Therapies 2020 20:20
  22. In Mozambique, bacterial and parasitic diseases contribute to a high burden of mortality and morbidity. These infectious diseases are treated with antibiotics, antihelmintic or antiparasitic drugs. However, mi...

    Authors: Filomena Barbosa, Delfina Hlashwayo, Victor Sevastyanov, Valeriano Chichava, Adilência Mataveia, Ernesto Boane and Aida Cala
    Citation: BMC Complementary Medicine and Therapies 2020 20:19
  23. Among women suffering from urinary incontinence (UI), about one-third are diagnosed with mixed urinary incontinence (MUI), among which urgency-predominant MUI causes more shame and inconvenience to patients. T...

    Authors: Yuanjie Sun, Yan Liu, Tongsheng Su, Jianhua Sun, Ying Wu and Zhishun Liu
    Citation: BMC Complementary Medicine and Therapies 2020 20:18
  24. The use of herbal medicine is on the rise worldwide, and safety issues associated with herbal medicines may have an exacerbated impact in elderly because this population has an increased susceptibility and sen...

    Authors: Carolina Miranda de Sousa Lima, Mayara Amoras Teles Fujishima, Bruno de Paula Lima, Patrícia Carvalho Mastroianni, Francisco Fábio Oliveira de Sousa and Jocivânia Oliveira da Silva
    Citation: BMC Complementary Medicine and Therapies 2020 20:17
  25. Quantitation analysis and chromatographic fingerprint of multi-components are frequently used to evaluate quality of herbal medicines but fail to reveal activity of the components. It is necessary to develop a...

    Authors: Hong-Ying Li, Jiang-Ji Fang, Hua-Dan Shen, Xue-Qiong Zhang, Xiao-Ping Ding and Jun-Feng Liu
    Citation: BMC Complementary Medicine and Therapies 2020 20:16
  26. Gastrointestinal cancer is one of the most common malignancies and imposes heavy burdens on both individual health and social economy. We sought to survey the effect of a self-care education program on quality...

    Authors: Jun Xie, Tingli Zhu, Qun Lu, Xiaomin Xu, Yinghua Cai and Zhenghong Xu
    Citation: BMC Complementary Medicine and Therapies 2020 20:15
  27. Euphorbia hirta (Linn) family Euphorbiaceae has been used in indigenous system of medicine for the treatment of gastrointestinal disorders. This study was designed to determine the pharmacological basis for the m...

    Authors: Muhammad Zeeshan Ali, Malik Hassan Mehmood, Muhammad Saleem and Anwarul-Hassan Gilani
    Citation: BMC Complementary Medicine and Therapies 2020 20:14
  28. Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease. Buyang Huanwu Tang (BYHWT), a classical traditional Chinese medicine formula, has been widely utilized for the treatment of PF in...

    Authors: Zi-fei Yin, Yang-lin Wei, Xuan Wang, Li-na Wang and Xia Li
    Citation: BMC Complementary Medicine and Therapies 2020 20:13
  29. Although cannabis and cannabinoids are widely used with therapeutic purposes, their claimed efficacy is highly controversial. For this reason, medical cannabis use is a broad field of research that is rapidly ...

    Authors: Nadia Montero-Oleas, Ingrid Arevalo-Rodriguez, Solange Nuñez-González, Andrés Viteri-García and Daniel Simancas-Racines
    Citation: BMC Complementary Medicine and Therapies 2020 20:12
  30. Cancer cachexia is a severe condition that leads to the death of advanced cancer patients, and approximately 50~80% of cancer patients have cancer cachexia. Ginseng extract has been reported to have substantia...

    Authors: Shuai Lu, Yubo Zhang, Huajun Li, Jing Zhang, Yingqian Ci and Mei Han
    Citation: BMC Complementary Medicine and Therapies 2020 20:11
  31. Although a variety of patient-reported outcome measures (PROMs) for children have been developed, there is no pediatric PROM specific to Korean medicine (KM) that is validated by experts in the field. The aim ...

    Authors: Jihong Lee, Sun Haeng Lee and Gyu Tae Chang
    Citation: BMC Complementary Medicine and Therapies 2020 20:10
  32. A variety of medicinal products prepared from secondary tubers of Harpagophytum procumbens subsp. procumbens (Burch.) DC.ex Meisn. (Devil’s Claw) and H. zeyheri are marketed in Africa, Europe, the United States, ...

    Authors: Kirtan Joshi, Alan Parrish, Elizabeth A. Grunz-Borgmann, Mary Gerkovich and William R. Folk
    Citation: BMC Complementary Medicine and Therapies 2020 20:9
  33. The proliferation and resistance of microorganisms area serious threat against humankind and the search for new therapeutics is needed. The present report describes the antiplasmodial and anticancer activities...

    Authors: Romeol Romain Koagne, Frederick Annang, Bastien Cautain, Jesús Martín, Guiomar Pérez-Moreno, Gabin Thierry M. Bitchagno, Dolores González-Pacanowska, Francisca Vicente, Ingrid Konga Simo, Fernando Reyes and Pierre Tane
    Citation: BMC Complementary Medicine and Therapies 2020 20:8
  34. As the dry rhizome of Anemone raddeana Regel, Rhizoma Anemones Raddeanae (RAR), which belongs to Ranunculaceae, is usually used to treat wind and cold symptoms, hand-foot disease and spasms, joint pain and ulcer ...

    Authors: Sha-Sha Wang, Shao-Yan Zhou, Xiao-Yan Xie, Ling Zhao, Yao Fu, Guang-Zhi Cai and Ji-Yu Gong
    Citation: BMC Complementary Medicine and Therapies 2020 20:7

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2020 20:310

  35. As an effective prescription for gastric cancer (GC), Compound Kushen Injection (CKI) has been widely used even though few molecular mechanism analyses have been carried out.

    Authors: Wei Zhou, Jiarui Wu, Yingli Zhu, Ziqi Meng, Xinkui Liu, Shuyu Liu, Mengwei Ni, Shanshan Jia, Jingyuan Zhang and Siyu Guo
    Citation: BMC Complementary Medicine and Therapies 2020 20:6
  36. Nigella sativa (NS), a member of family Ranunculaceae is commonly known as black seed or kalonji. It has been well studied for its therapeutic role in various diseases, particularly cancer. Literature is full of ...

    Authors: Yamna Khurshid, Basir Syed, Shabana U. Simjee, Obaid Beg and Aftab Ahmed
    Citation: BMC Complementary Medicine and Therapies 2020 20:5
  37. Complementary and alternative medicine and therapies (CAM) are widely used by parents of children with autism spectrum disorder (ASD). However, there is a gap in our understanding of how and why parents of chi...

    Authors: Caroline A. Smith, Chloe Parton, Marlee King and Gisselle Gallego
    Citation: BMC Complementary Medicine and Therapies 2020 20:4
  38. Xiao-ai-ping injection (XAPI), as patented Chinese medicine, has shown promising outcomes in non-small-cell lung cancer (NSCLC) patients. This meta-analysis investigated the efficacy and safety of XAPI in comb...

    Authors: Fanchao Feng, Jingyi Huang, Zhichao Wang, Jiarui Zhang, Di Han, Qi Wu, Hailang He and Xianmei Zhou
    Citation: BMC Complementary Medicine and Therapies 2020 20:3
  39. Echinops kebericho is widely used for treatment of a variety of diseases including infectious, non-infectious disease and fumigation during child birth. Antibacterial, antimalarial, anti-leshimania, anti-diarrhea...

    Authors: Serawit Deyno, Abiy Abebe, Mesfin Asefa Tola, Ariya Hymete, Joel Bazira, Eyasu Makonnen and Paul E. Alele
    Citation: BMC Complementary Medicine and Therapies 2020 20:2
  40. Cordyceps militaris (L.) Fr. (C. militaris) exhibits pharmacological activities, including antitumor properties, through the regulation of the nuclear factor kappa B (NF-κB) signaling. Tumor Necrosis Factor (TNF)...

    Authors: Eunbi Jo, Hyun-Jin Jang, Kyeong Eun Yang, Min Su Jang, Yang Hoon Huh, Hwa-Seung Yoo, Jun Soo Park, Ik-Soon Jang and Soo Jung Park
    Citation: BMC Complementary Medicine and Therapies 2020 20:1
  41. The use of Complementary Medicines (CMs) has significantly increased in Australia over the last decade. This study attempts to determine the extent to which complementary and alternative medicines are recorded...

    Authors: Freya Waddington, Jenny Lee, Mark Naunton, Greg Kyle, Jackson Thomas and Gabrielle O’Kane
    Citation: BMC Complementary and Alternative Medicine 2019 19:374
  42. Tempeh is a widely known fermented soybean that contains elevated level of bioactive contents. Our previous study has shown that anaerobic fermented Nutrient Enriched Soybean Tempeh (NESTE) with increase amino...

    Authors: Hamidah Mohd Yusof, Norlaily Mohd Ali, Swee Keong Yeap, Wan Yong Ho, Boon Kee Beh, Soo Peng Koh, Kamariah Long and Noorjahan Banu Alitheen
    Citation: BMC Complementary and Alternative Medicine 2019 19:373
  43. Vernonia anthelmintica (L.) willd is a traditional urgur herb in China for a long history. Its alcohol extract (AVE) has been proved to promote hair follicle growth in C57BL/6 mice. We conducted this study to inv...

    Authors: Qian Wang, Yongxin Wang, Silin Pang, Jia Zhou, Jie Cai and Jing Shang
    Citation: BMC Complementary and Alternative Medicine 2019 19:372
  44. Canscora lucidissima (Levl. & Vaniot) Hand.-Mazz. (C. lucidissima), mainly distributed in southern China, has been shown to be effective in the treatment of inflammatory diseases. However, the underlying mechanis...

    Authors: Qiao-ling Fei, Xiao-yu Zhang, Rui-juan Qi, Yun-feng Huang, Yi-xin Han, Xi-meng Li, Run-lan Cai, Yuan Gao and Yun Qi
    Citation: BMC Complementary and Alternative Medicine 2019 19:371
  45. Tianshu capsule (TSC), a formula of traditional Chinese medicine, has been widely used in clinical practice for prophylactic treatment of headaches in China. However, former clinical trials of TSC were small, ...

    Authors: Shengyuan Yu, Ye Ran, Wei Xiao, Wenjing Tang, Jianjun Zhao, Wei Chen, Huikui Zhuang, Cun Ouyang, Hai Lin, Dequan Liu, Tongjun Chen, Hui Huang, Baoshen Wang, Yanlei Hao, Zhongrui Yan, Shike Zhao…
    Citation: BMC Complementary and Alternative Medicine 2019 19:370
  46. Bletilla striata is a traditional Chinese medicine used to treat hemorrhage, scald, gastric ulcer, pulmonary diseases and inflammations. In this study, we investigated bioactivity of the effective fraction of B. ...

    Authors: Yu-Yao Zu, Quan-Fang Liu, Shu-Xin Tian, Li-Xia Jin, Fu-Sheng Jiang, Mei-Ya Li, Bing-Qi Zhu and Zhi-Shan Ding
    Citation: BMC Complementary and Alternative Medicine 2019 19:369
  47. Obesity and its associated health conditions, type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD), are worldwide health problems. It has been shown that insulin resistance is associate...

    Authors: Ting-Chen Chang, Hao Chiang, Yu-Heng Lai, Yu-Ling Huang, Hsiu-Chen Huang, Yu-Chih Liang, Hui-Kang Liu and Cheng Huang
    Citation: BMC Complementary and Alternative Medicine 2019 19:368
  48. ChondroT, a new herbal medication, consists of Angelica grosseserrata Maxim., Lonicera japonica Thunb., Angelica gigas Nakai, Clematis terniflora var. manshurica (Rupr.) Ohwi, and Phellodendron amurense Rupr. (6:...

    Authors: Jiwon Jeong, Kiljoon Bae, Jihoon Kim, Chanhun Choi, Changsu Na, Myeongkyu Park, Youngran Kim, Chang-Seob Seo and Seon-Jong Kim
    Citation: BMC Complementary and Alternative Medicine 2019 19:367
  49. Marsdenia tenacissima extract (MTE) is a phytochemical widely used as complementary therapy in cancer care. This systematic review was conducted to investigate the anticancer and detoxification effects of MTE, as...

    Authors: Xu Zhou, Meilu Liu, Qing Ren, Weifeng Zhu, Yang Wang, Haochen Chen and Jianrong Chen
    Citation: BMC Complementary and Alternative Medicine 2019 19:366
  50. The edible fruit Annona cherimola has previously shown many nutritional and medicinal properties. The current study evaluates the anti-cancer and anti-proliferative properties of Annona cherimola ethanolic leaf e...

    Authors: Carl Ammoury, Maria Younes, Marianne El Khoury, Mohammad H. Hodroj, Tony Haykal, Peter Nasr, Marilyne Sily, Robin I. Taleb, Rita Sarkis, Rana Khalife and Sandra Rizk
    Citation: BMC Complementary and Alternative Medicine 2019 19:365