Choi MS, Park JW. A study of educational need, attitude and knowledge toward menopause in middle-aged women. Korean J Women Health Nurs. 2008;14:257–69.
Article
Google Scholar
Dalal PK, Agarwal M. Postmenopausal syndrome. Indian J Psychiatry. 2015;57:222–32.
Article
Google Scholar
Nelson HD. Menopause. Lancet. 2008;371:760–70.
Article
PubMed
Google Scholar
Doyle BJ, Frasor J, Bellows LE, et al. Estrogenic effects of herbal medicines from Costa Rica used for the management of menopausal symptoms. Menopause. 2009;16(4):748–55.
Article
PubMed
PubMed Central
Google Scholar
Hibler E, Kauderer J, Greene MH, Rodriguez GC, Alberts DS. Bone loss following oophorectomy among high-risk women: an NRG oncology/gynecologic oncology group study. Menopause. 2016;23(11):1228.
Article
PubMed
PubMed Central
Google Scholar
Di Vasta AD, Feldman HA, Gallagher JS, Stokes NA, Laufer MR, Hornstein MD, Gordon CM. Hormonal add-back therapy for females treated with gonadotropin-releasing hormone agonist for endometriosis: a randomized controlled trial. Obstet Gynecol. 2015;126(3):617.
Article
CAS
Google Scholar
Golob AL, Laya MB. Osteoporosis: screening, prevention, and management. Med Clin North Am. 2015;99(3):587–606.
Article
PubMed
Google Scholar
He C, Hui R, Tezuka Y, Kadota S, Li J. Osteoprotective effect of extract from Achyranthes bidentata in ovariectomized rats. J Ethnopharmacol. 2010;127(2):229–34.
Article
PubMed
Google Scholar
Richelson LS, Wahner HW, Melton LJ, Riggs BL. Relative contributions of aging and estrogen deficiency to postmenopausal bone loss. N Engl J Med. 1984;311:1273–5.
Article
CAS
PubMed
Google Scholar
Arjmandi BH, Johnson SA, Pourafshar SH, Navaei NH, George KS, Akhavan NS. Dried Plum’s unique ability to prevent and reverse bone loss in ovarian hormone deficiency: efficacy and possible mechanisms. FASEB J. 2017;31:151–8.
Google Scholar
Bark C. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. 2008;3:S131–9.
Article
CAS
Google Scholar
Shetty S, Kapoor N, Bondu JD, Thomas N, Paul TV. Bone turnover markers: emerging tool in the management of osteoporosis. Indian J Endocr Metab. 2016;20(6):846.
Article
Google Scholar
Van Kempen TA, Milner TA, Waters EM. Accelerated ovarian failure: a novel, chemically induced animal model of menopause. Brain Res. 2011;1379:176–87.
Article
PubMed
PubMed Central
CAS
Google Scholar
Brinton RD. Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action. Ann N Y Acad Sci. 2005;1052:57–74.
Article
CAS
PubMed
Google Scholar
Brinton RD. Mini review: translational animal models of human menopause: challenges and emerging opportunities. Endocrinology. 2012;153(8):3571–8.
Article
CAS
Google Scholar
Faulds MH, Zhao C, Dahlman-Wright K, Gustafsson JÅ. The diversity of sex steroid action: regulation of metabolism by estrogen signaling. J Endocrinol. 2012;212:3–12.
Article
CAS
PubMed
Google Scholar
Lobo RA. Androgens in postmenopausal women: production, possible role, and replacement options. Obstet Gynecol Surv. 2001;56(6):361–76.
Article
CAS
PubMed
Google Scholar
Nelson HD, Haney EM, Humphrey L, Miller J, Nedrow A, Nicolaidis C, Nygren P. Management of menopause-related symptoms. Summary, evidence technology assessment no 120. (prepared by the Oregon evidence based practice center, under contract no 290–02-0024). AHRQ publication no 05-E016–1. Rockville: Agency for healthcare research and quality; 2005.
Google Scholar
Bonilla-Becerra SM, de Oliveira MG, Calmasini FB, Rojas-Moscoso JA, Zanesco A, Antunes E. Micturition dysfunction in four-month old ovariectomized rats: effects of testosterone replacement. Life Sci. 2017;179:120–9.
Article
CAS
PubMed
Google Scholar
Talbott SM, Talbott JA, George A, et al. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. J Int Soc Sports Nutr. 2013;10:28.
Article
PubMed
PubMed Central
Google Scholar
Suh KS. Discovery of novel biomarkers for the development of personalized medicine. Transl Med. 2012;S1:e1–2.
Google Scholar
Teh CH, Teoh SC, Yeap CS, Chan KL, Fun HK. 4, 5, 7, 8, 17-Pentahydroxy-14, 18-dimethyl-6-methylene-3, 10-dioxapentacyclo [9.8. 0.01, 7.04, 19.013, 18] nonadec-14-ene-9, 16-dione methanol solvate dehydrate. Acta Crystallogr Sect E: Struct Rep Online. 2009;65:898–9.
Article
CAS
Google Scholar
Shuid AN, Ping LL, Muhammad N, Mohamed N, Soelaiman IN. The effects of Labisia pumila var. alata on bone markers and bone calcium in a rat model of post-menopausal osteoporosis. J Ethnopharmacol. 2011;133(2):538–42.
Article
PubMed
Google Scholar
Rehman S, Choe K, Yoo H. Review on a traditional herbal medicine, Eurycoma longifolia Jack (Tongkat Ali): its traditional uses, chemistry, evidence-based pharmacology and toxicology. Molecules. 2016;21(3):331.
Article
PubMed
PubMed Central
CAS
Google Scholar
Tambi MI, Imran, MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat Ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia. 2010;44:1–5.
Article
PubMed
CAS
Google Scholar
Davison S, Davis SR. Hormone replacement therapy: current controversies. Clin Endocrinol. 2003;58:249–61.
Article
CAS
Google Scholar
Stevenson JC. Justification for the use of HRT in the long term prevention of osteoporosis. Maturitas. 2005;51:113–26.
Article
CAS
PubMed
Google Scholar
Lee YH, Jin B, Lee S, Oh JY, Song J, Lee D, Kim YS, Kim H. A herbal formula HT051, a combination of Pueraria lobata and Rehmannia glutinosa, prevents postmenopausal obesity in ovariectomized rats. Evid Based Complement Alternat Med. 2017.
Tanidir Y, Ercan F, Tarcan T. Exogenous testosterone and estrogen affect bladder tissue contractility and histomorphology differently in rat ovariectomy model. J Sex Med. 2011;8(6):1626–37.
Article
PubMed
Google Scholar
Choudhary YK, Bommu P, Ming YK, Zulkawi NB. Acute, sub-acute, and subchronic 90-days toxicity of Eurycoma longifolia aqueous extract (Physta) in wistar rats. Int J Pharm Pharm Sci. 2012;4(3).
Department of Standards Malaysia. Phytochemical aspect of freeze dried water extract from Tongkat Ali roots- specification. (Malaysian standard MS 2409:2011/ICS:67.040). Shah Alam: Department of Standards Malaysia, Ministry of Science, Technology and Innovation, Cyberjaya, Malaysia/ Standards & Industrial Research Institute of Malaysia (SIRM); 2011.
Google Scholar
The University of British Columbia. Rodent anaesthesia and analgesic formulary and general drug information. Canada: The University of British Columbia, Animal care committee SOP/Guidelines; 2016.
Google Scholar
Behr GA, Schnorr CE, Moreira JC. Increased blood oxidative stress in experimental menopause rat model: the effects of vitamin a low-dose supplementation upon antioxidant status in bilateral ovariectomised rats. Fundam Clin Pharmacol. 2012;26(2):235–49.
Article
CAS
PubMed
Google Scholar
Kim D, Choi MS, Pak SC, Lee SB, Jeon S. The effects of Sutaehwan-Gami on menopausal symptoms induced by ovariectomy in rats. BMC Complement Altern Med. 2012;12:227.
Article
PubMed
PubMed Central
Google Scholar
Xue L, Wang Y, Jiang Y, Han T, Nie Y, Zhao L, Qin L. Comparative effects of er-xian decoction, epimedium herbs, and icariin with estrogen on bone and reproductive tissue in ovariectomised rats. Evid Based Complement Alternat Med. 2012;2012:241416.
PubMed
PubMed Central
Google Scholar
Bongartz TA, Scholmerich J, Straub RH. In: Maricic M, Gluck OS, editors. From osteoporosis in postmenopausal women. In Bone disease in rheumatology. Arizona: Lippincott Williams and Wilkens; 2005. p. 155–6.
Google Scholar
Elkomy MM, Elsaid FG. Anti-osteoporotic effect of medical herbs and calcium supplementation on ovariectomized rats. J Basic Appl Zool. 2015;72:81–8.
Article
CAS
Google Scholar
Shiraishi A, Takeda S, Masaki T, Higuchi Y, Uchiyama Y, Kubodera N, Ogata E. Alfacalcidol inhibits bone resorption and stimulates formation in an ovariectomized rat model of osteoporosis: distinct actions from estrogen. J Bone Miner Res. 2000;15(4):770–9.
Article
CAS
PubMed
Google Scholar
Bhattarai T, Bhattacharya K, Chaudhuri P, Sengupta P. Correlation of common biochemical markers for bone turnover, serum calcium, and alkaline phosphatase in post-menopausal women. MJMS. 2014;21(1):58.
PubMed
PubMed Central
Google Scholar
Jayusman PA, Mohamed IN, Alias E, Dom SM, Shuid AN. Effects of standardized quassinoid-rich Eurycoma longifolia extract in a rat model of osteoporosis due to testosterone deficiency: A densitometric, morphometric and biomechanical study. J Xray Sci Technol. 2018; (Preprint):1–14.
Xie F, Wu CF, Lai WP, Yang XJ, Cheung PY, Yao XS, Leung PC, Wong MS. The osteoprotective effect of Herbaepimedii (HEP) extract in vivo and in vitro. Evid Based Complement Alternat Med. 2005;2:353–61.
Article
PubMed
PubMed Central
Google Scholar
Brokaw JJ, Tunnicliff G, Raess BU, Saxon DW. The teaching of complementary and alternative medicine in U.S. medical schools: a survey of course directors. Acad Med. 2002;77(9):876–81.
Article
PubMed
Google Scholar
Kargozar R, Azizi H, Salari R. A review of effective herbal medicines in controlling menopausal symptoms. Electron Physician. 2017;9(11):5826–33.
Article
PubMed
PubMed Central
Google Scholar
Low BS, Das PK, Chan KL. Standardized quassinoid-rich Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic–pituitary–gonadal axis. J Ethnopharmacol. 2013;145(3):706–14.
Article
CAS
PubMed
Google Scholar
Ali JM, Saad JM. Biochemical effect of Eurycoma longifolia jack on the sexual behavior, fertility, sex hormone, and glycolysis. Department of Biochemistry, University of Malaysia: PhD Dissertation; 1993.
Google Scholar
George A, Henkel R. Phytoandrogenic properties of Eurycoma longifolia as natural alternative to testosterone replacement therapy. Andrologia. 2014;46(7):708–21.
Article
CAS
PubMed
Google Scholar