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  1. Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder diagnosed during adolescence and adulthood. Assessment of the long-term risks of the current drugs for ADHD treatment has been i...

    Authors: Kairui Tang, Wenzhi Hao, Xiaowei Mo, Yueyue Chen, Xiaofang Guo, Liangliang He, Binghua Wang, Juxian Wang, Qingyu Ma, Lijuan Deng and Jiaxu Chen

    Citation: BMC Complementary Medicine and Therapies 2022 22:24

    Content type: Research

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  2. Traditional plant-based remedies prescribed to treat diabetes have shown promise in research-based setting. Current research was conducted to examine the antidiabetic and antioxidant effects of methanolic extr...

    Authors: Imtiaz Mustafa, Haseeb Anwar, Shahzad Irfan, Humaira Muzaffar and Muhammad Umar Ijaz

    Citation: BMC Complementary Medicine and Therapies 2022 22:23

    Content type: Research

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  3. To evaluate veteran patient and provider perceptions and preferences on complementary and integrative medicine (CIM) for headache management.

    Authors: Deena E. Kuruvilla, Hayley Lindsey, Amy S. Grinberg, Roberta E. Goldman, Samantha Riley, Sean Baird, Brenda T. Fenton, Jason J. Sico and Teresa M. Damush

    Citation: BMC Complementary Medicine and Therapies 2022 22:22

    Content type: Research

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  4. Osbeckia octandra is a plant endemic to Sri Lanka and is used in ethnomedicine for treating various diseases. However, the anti-cancer properties of O. octandra are yet to be fully investigated. In the present s...

    Authors: Jue Young Kim, Jin Kim, B. M. Ratnayake Bandara, Wanninayake M. Tilakaratne and Dokyeong Kim

    Citation: BMC Complementary Medicine and Therapies 2022 22:20

    Content type: Research

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  5. Vitamin D has an established role in female reproduction. There is also evidence for an association between vitamin D levels and menstrual problems such as premenstrual syndrome (PMS) and dysmenorrhea. Curcumi...

    Authors: Leyla Arabnezhad, Mahtab Mohammadifard, Ladan Rahmani, Zahra Majidi, Gordon A. Ferns and Afsane Bahrami

    Citation: BMC Complementary Medicine and Therapies 2022 22:19

    Content type: Research

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  6. Breast Cancer (BC) is the most common cancer in women worldwide and, although 70% of patients are responsive to selective Estrogen Receptor (ER) modulators such as Tamoxifen (Tam), patients’ survival is compri...

    Authors: Douglas C. Brandão, Paula M. A. P. Lima, Isabella C. Martins, Carina S. Cordeiro, Antonielle O. Cordeiro, Lara Vecchi, Joyce F. C. Guerra, Priscila C. Orsolin, Matheus C. Gazolla, Danilo S. Costa, Ademar A. da Silva Filho and Thaise G. Araújo

    Citation: BMC Complementary Medicine and Therapies 2022 22:18

    Content type: Research

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  7. Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease with scantly effective treatment. Numerous evidences indicated that macrophages play an important role in the occurrence and patho...

    Authors: Xiao Lin, Xiao-qin Lei, Jie-ke Yang, Jian Jia, Xia Zhong, Rui-zhi Tan and Li Wang

    Citation: BMC Complementary Medicine and Therapies 2022 22:17

    Content type: Research

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  8. Several local communities in Central, Western, Eastern, and Northern regions of Uganda have been using the whole leaf extracts of Aloe vera (L.) Burm. f. (Asphodelaceae) in the treatment of various ailments. Also...

    Authors: Florence Nalimu, Joseph Oloro, Emanuel L. Peter and Patrick Engeu Ogwang

    Citation: BMC Complementary Medicine and Therapies 2022 22:16

    Content type: Research

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  9. High glucose concentration increases the glycation process which leads to oxidative stress and inflammation, that can cause complications in diabetes. Several medicinal plants have been used in the treatment o...

    Authors: Evy Yulianti, Sunarti and Mae Sri Hartati Wahyuningsih

    Citation: BMC Complementary Medicine and Therapies 2022 22:15

    Content type: Research article

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  10. Traditional and Complementary Medicine (TCM) is widely used particularly among patients with chronic diseases in primary care. However, evidence is lacking regarding TCM use among patients with Metabolic Syndr...

    Authors: Nor Farha Basri, Anis Safura Ramli, Mariam Mohamad and Khairatul Nainey Kamaruddin

    Citation: BMC Complementary Medicine and Therapies 2022 22:14

    Content type: Research

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  11. P-glycoprotein (P-gp)-mediated steroid resistance (SR) has been suggested to play a significant role in lupus nephritis (LN) treatment failure. Panax notoginseng saponins (PNS), the main effective components o...

    Authors: Feng Pan, Yue-jin Li and Ying Lu

    Citation: BMC Complementary Medicine and Therapies 2022 22:13

    Content type: Research article

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  12. Rubus occidentalis, also known as black raspberry, contains several bioactive components that vary depending on the maturity of the fruit. The goal of this study was to evaluate the efficacy of immature Rubus oc...

    Authors: Geun Joo Choi, Hyun Kang, Oh Haeng Lee, Eun Jin Ahn, Fletcher A. White, Ye Jin Cho, Chong Wha Baek, Yong Hun Jung and Ji Wung Kwon

    Citation: BMC Complementary Medicine and Therapies 2022 22:12

    Content type: Research article

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  13. Cerebral malaria is one of the most severe complications attributed to protozoal infection by Plasmodium falciparum, gaining prominence in children mortality rates in endemic areas. This condition has a complex p...

    Authors: Karen Renata Herculano Matos Oliveira, Marjorie Lujan Marques Torres, Nayara Kauffmann, Brenda Jaqueline de Azevedo Ataíde, Nívia de Souza Franco Mendes, Larissa Medeiros dos Anjos, Rosivaldo dos Santos Borges, Carlomagno Pacheco Bahia, Luana Ketlen Reis Leão, Adelaide da Conceição Fonseca Passos, Anderson Manoel Herculano and Evander de Jesus Oliveira Batista

    Citation: BMC Complementary Medicine and Therapies 2022 22:11

    Content type: Research

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  14. Epithelial-to-mesenchymal transition (EMT) is a pivotal cellular phenomenon involved in tumour metastasis and progression. In gastric cancer (GC), EMT is the main reason for recurrence and metastasis in postop...

    Authors: Guangtao Zhang, Zhaoyan Li, Jiahuan Dong, Weili Zhou, Zhanxia Zhang, Zujun Que, Xiaohong Zhu, Yan Xu, Nida Cao and Aiguang Zhao

    Citation: BMC Complementary Medicine and Therapies 2022 22:10

    Content type: Research

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  15. Bletilla striata is the main medicine of many skin whitening classic formulas in traditional Chinese medicine (TCM) and is widely used in cosmetic industry recently. However, its active ingredients are still uncl...

    Authors: Yiyuan Luo, Juan Wang, Shuo Li, Yue Wu, Zhirui Wang, Shaojun Chen and Hongjiang Chen

    Citation: BMC Complementary Medicine and Therapies 2022 22:9

    Content type: Research

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  16. The use of traditional medicinal plants in the management of diarrhea has long been practiced in Ethiopia. B. abyssinica fresen is one of the plants traditionally used to treat diarrhea whereas an in vivo study h...

    Authors: Mihret Ayalew, Azmeraw Bekele, Mestayet Geta Mengistie and Seyfe Asrade Atnafie

    Citation: BMC Complementary Medicine and Therapies 2022 22:8

    Content type: Research

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  17. Patrinia scabra Bunge is a well-known herbal medicine for its favorable treatment on inflammatory diseases owing to its effective ingredients, in which iridoid glycoside plays an extremely significant role. This ...

    Authors: Quhuan Ma, Yanmei Lu, Yi Deng, Xiaodong Hu, Wanyu Li, Hongzhen Jia, Yuer Guo and Xiaofeng Shi

    Citation: BMC Complementary Medicine and Therapies 2022 22:7

    Content type: Research

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  18. Quercus acuta Thunb. (Fagaceae) or Japanese evergreen oak is cultivated as an ornamental plant in South Korea, China, Japan, and Taiwan and used in traditional medicine. The acorn or fruit of Quercus acuta Thunb....

    Authors: Ji-Ae Hong, Donghyuk Bae, Kyo-Nyeo Oh, Dool-Ri Oh, Yujin Kim, Yonguk Kim, So Jeong Im, Eun-jin Choi, Seul-gi Lee, Moonjong Kim, Changsik Jeong and Chul Yung Choi

    Citation: BMC Complementary Medicine and Therapies 2022 22:6

    Content type: Research

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  19. Trifolium pratense (red clover) ethanolic extract (TPEE) has been used as a popular over-the-counter remedy for the management of menopausal symptoms. Prolonged consumption of herbal extract has been shown to reg...

    Authors: Yixian Quah, Na-Hye Park, Eon-Bee Lee, Ki-Ja Lee, Jireh Chan Yi-Le, Md. Sekendar Ali, Seung-Hee Jang, Min-Jeong Kim, Seung-Jin Lee and Seung-Chun Park

    Citation: BMC Complementary Medicine and Therapies 2022 22:5

    Content type: Research

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  20. Though Lippia javanica (Burm.f.) Spreng antioxidant activity has been demonstrated, its effect in protecting the brain from lead (Pb)-induced oxidative damage is unknown. This study investigated the effect of L. ...

    Authors: Zubair Suleman, Godwill A. Engwa, Mathulo Shauli, Hannibal T. Musarurwa, Ndinashe A. Katuruza and Constance R. Sewani-Rusike

    Citation: BMC Complementary Medicine and Therapies 2022 22:4

    Content type: Research

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  21. Psychological risk factors have been recognised as potential, modifiable risk factors in the development and progression of cardiovascular disease (CVD). Tai Chi, a mind-body exercise, has the potential to imp...

    Authors: Guoyan Yang, Wenyuan Li, Nerida Klupp, Huijuan Cao, Jianping Liu, Alan Bensoussan, Hosen Kiat, Diana Karamacoska and Dennis Chang

    Citation: BMC Complementary Medicine and Therapies 2022 22:3

    Content type: Research article

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  22. Whole-body vibration (WBV) training can provoke reactive muscle response and thus exert beneficial effects in various neurological patients. This study aimed to investigate the muscles activation and accelerat...

    Authors: Chia-Ming Chang, Chon-Haw Tsai, Ming-Kuei Lu, Hsin-Chun Tseng, Grace Lu, Bey-Ling Liu and Hsiu-Chen Lin

    Citation: BMC Complementary Medicine and Therapies 2022 22:2

    Content type: Research

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  23. This study aimed to evaluate the cost-effectiveness of vitamin D supplementation in preventing type 2 diabetes mellitus (T2DM) among Iranian adolescents.

    Authors: Narges Zandieh, Mohsen Rezaei Hemami, Ali Darvishi, Seyed Mohammad Hasheminejad, Zahra Abdollahi, Maryam Zarei and Ramin Heshmat

    Citation: BMC Complementary Medicine and Therapies 2022 22:1

    Content type: Research

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  24. In recent years, 1, 2, 4-triazole and its derivatives have been reported to be pharmacologically significant scaffolds. They possess analgesic, anti-tubercular, anti-inflammatory, anti-convulsant, anti-oxidant...

    Authors: Tabinda Azim, Muhammad Wasim, Muhammad Shoaib Akhtar and Irfan Akram

    Citation: BMC Complementary Medicine and Therapies 2021 21:304

    Content type: Research

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  25. Despite the considerable advances made in the treatment of cancer, it remains a global threat. Tartrazine (E102) is a synthetic dye widely used in food industries; it has recently been shown to induce oxidativ...

    Authors: Stéphane Zingue, Elisabeth Louise Ndjengue Mindang, Florence Charline Awounfack, Abel Yanfou Kalgonbe, Moustapha Mohamet Kada, Dieudonné Njamen and Derek Tantoh Ndinteh

    Citation: BMC Complementary Medicine and Therapies 2021 21:303

    Content type: Research

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  26. Oxidative stress (OS) and inflammation are the central pathogenic events in liver diseases. In this study, the protective and therapeutic role of Carica Papaya Linn. seeds extract (SE) was evaluated against the h...

    Authors: Nadia Z. Shaban, Sarah M. El-Kot, Olfat M. Awad, Afaf M. Hafez and Ghada M. Fouad

    Citation: BMC Complementary Medicine and Therapies 2021 21:302

    Content type: Research

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  27. Benign prostatic hyperplasia (BPH) is a major urologic problem that mostly develops in older males. Oxidative stress and inflammation influence the occurrence of BPH. Berberine (BBR) is a natural ingredient th...

    Authors: Ehsan Shabani, Heibatullah Kalantari, Mojtaba Kalantar, Mehdi Goudarzi, Esrafil Mansouri and Hadi Kalantar

    Citation: BMC Complementary Medicine and Therapies 2021 21:301

    Content type: Research

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  28. Antimicrobial drug resistance is a major public health threat that can render infections including wound and skin infections untreatable. The discovery of new antimicrobials is critical. Approaches to discover...

    Authors: Pauline McLoone, Aizhan Zhumbayeva, Sofiya Yunussova, Yerkhat Kaliyev, Ludmila Yevstafeva, Susan Verrall, Julie Sungurtas, Ceri Austin, J. Will Allwood and Gordon J. McDougall

    Citation: BMC Complementary Medicine and Therapies 2021 21:300

    Content type: Research article

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  29. Recently, extracellular vesicles have come to the fore following their emerging role in cell communication, thanks to their ability to reach cells into the human body without dissipating their cargo, transferr...

    Authors: Riccardo Tassinari, Claudia Cavallini, Elena Olivi, Valentina Taglioli, Chiara Zannini, Orlando Ferroni and Carlo Ventura

    Citation: BMC Complementary Medicine and Therapies 2021 21:299

    Content type: Research

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  30. The transition from student to practitioner can be challenging, resulting in stress, burnout and attrition. While there has been ample research examining graduate medical and allied health practitioner experie...

    Authors: Matthew J. Leach, Larisa A. J. Barnes, Andy McLintock, Helene M. Diezel, Kimberley Ryan and Amie E. Steel

    Citation: BMC Complementary Medicine and Therapies 2021 21:298

    Content type: Research

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  31. Osteoarthritis (OA) of the knee is one of the most common chronic degenerative joint diseases, and a multi-disciplinary approach to educating patients with OA knee are effective in symptoms management. Tai Chi...

    Authors: Kevin Ki-Wai Ho, Gerald Pong, Queena Wai-Chin Poon, Jojo Yan-Yan Kwok, Wai-Wang Chau and Michael Tim-Yun Ong

    Citation: BMC Complementary Medicine and Therapies 2021 21:297

    Content type: Research

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  32. Podocytes have become a crucial target for interventions in proteinuric kidney diseases. Many studies have reported that overexpression of transient receptor potential cation channel protein 6 (TRPC6) in podoc...

    Authors: Yin Ding, Xuanli Tang, Yuhui Wang, Dongrong Yu, Caifeng Zhu and Jin Yu

    Citation: BMC Complementary Medicine and Therapies 2021 21:296

    Content type: Research

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  33. Sleep disruption is a major public health issue and may increase the risk of mortality by ten-folds if an individual is sleeping less than 6 h per night. Sleep has changed dramatically during to the COVID-19 p...

    Authors: Tsung-Ju Li, Tung-Yen Lee, Yun Lo, Li-Ya Lee, I-Chen Li, Chin-Chu Chen and Fang-Chia Chang

    Citation: BMC Complementary Medicine and Therapies 2021 21:295

    Content type: Research

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  34. Falcaria vulgaris Bernh among the most important member of Apiaceae family has been used for medical investigation in Iran and some regions in the world. This plant possesses a range of coumarin and flavonoids c...

    Authors: Kamran Hosseini, Sanaz Jasori, Abbas Delazar, Parina Asgharian and Vahideh Tarhriz

    Citation: BMC Complementary Medicine and Therapies 2021 21:294

    Content type: Research

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  35. Health promotion and patient education are crucial to improved population health and are also among the core principles that define naturopathy. Yet, the activities of naturopathic practitioners (NPs) with reg...

    Authors: Amie Steel and Iva Lloyd

    Citation: BMC Complementary Medicine and Therapies 2021 21:293

    Content type: Research article

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  36. Central obesity and insulin resistance are associated with metabolic syndrome (MetS) which is aggravated by diet and sedentary lifestyle. Athrixia phylicoides (AP) is reported by rural communities to have medicin...

    Authors: Madigoahle A. M. Mokwena, Godwill Azeh Engwa, Benedicta N. Nkeh-Chungag and Constance R. Sewani-Rusike

    Citation: BMC Complementary Medicine and Therapies 2021 21:292

    Content type: Research

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  37. Insulin resistance and hormonal imbalances are key features in the pathophysiology of polycystic ovarian syndrome (PCOS). We have previously shown that Ficus deltoidea var. deltoidea Jack (Moraceae) can improve i...

    Authors: Muhammad Aliff Haslan, Nurdiana Samsulrizal, Nooraain Hashim, Noor Syaffinaz Noor Mohamad Zin, Farshad H. Shirazi and Yong Meng Goh

    Citation: BMC Complementary Medicine and Therapies 2021 21:291

    Content type: Research

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  38. Trypanosomiasis is one of the neglected tropical diseases of both humans and animals which decreases their productivity and causes death in the worst scenario. Unavailability of vaccines, the low therapeutic i...

    Authors: Ayechew Yetayeh Emiru, Eyasu Makonnen, Fikru Regassa, Fekadu Regassa and Takele Beyene Tufa

    Citation: BMC Complementary Medicine and Therapies 2021 21:290

    Content type: Research

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  39. H9N2 avian influenza viruses (AIVs) infect avian and mammalian hosts and provide internal genes for new emerging highly pathogenic avian viruses that cause severe pneumonia with high mortality, for which few m...

    Authors: Beixian Zhou, Linxin Wang, Yueyun Liang, Jing Li and Xiping Pan

    Citation: BMC Complementary Medicine and Therapies 2021 21:289

    Content type: Research

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  40. Our previous study indicated that Potentilla reptans root has a preconditioning effect by its antioxidant and anti-apoptotic effects in an isolated rat heart ischemia/reperfusion (IR) model. In the present study,...

    Authors: Ayesheh Enayati, Aref Salehi, Mostafa Alilou, Hermann Stuppner, Mirali Polshekan, Maryam Rajaei, Mona Pourabouk, Ali Jabbari, Zohreh Mazaheri, Narguess Yassa, Hamid Reza Moheimani and Vahid Khori

    Citation: BMC Complementary Medicine and Therapies 2021 21:288

    Content type: Research

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  41. Pseudomonas aeruginosa is the most common Gram-negative bacterium associated with nosocomial respiratory infections. Lavender essential oil is mainly used in aromatherapy, but it has several pharmacological and ...

    Authors: Edina Pandur, Alex Balatinácz, Giuseppe Micalizzi, Luigi Mondello, Adrienn Horváth, Katalin Sipos and Györgyi Horváth

    Citation: BMC Complementary Medicine and Therapies 2021 21:287

    Content type: Research

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  42. Oral candidiasis is an opportunistic disease caused by fungi of the Candida genus. The occurrence of Candida spp. resistance to the commercial antifungal drugs points to the search for alternative treatments. Pro...

    Authors: Ana Rita Sokolonski, Maísa Santos Fonseca, Bruna Aparecida Souza Machado, Kathleen Ramos Deegan, Roberto Paulo Correia Araújo, Marcelo Andrés Umsza-Guez, Roberto Meyer and Ricardo W. Portela

    Citation: BMC Complementary Medicine and Therapies 2021 21:286

    Content type: Research article

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  43. The results of recent surveys indicate that more than 50% of the German population has experience with complementary and alternative medicine (CAM) or uses CAM regularly. This study investigated the CAM usage ...

    Authors: Ann-Kathrin Lederer, Alexandra Baginski, Lena Raab, Stefanie Joos, Jan Valentini, Carina Klocke, Yvonne Samstag, Katrin Hübner, Ivana Andreeva, Thomas Simmet, Tatiana Syrovets, Susanne Hafner, Anna Freisinger, Maximilian Andreas Storz and Roman Huber

    Citation: BMC Complementary Medicine and Therapies 2021 21:285

    Content type: Research

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  44. Stephania yunnanensis H. S. Lo is widely used as an antipyretic, analgesic and anti-inflammatory herbal medicine in SouthWest China. In this study, we investigated the anti-inflammatory activity and mechanism of...

    Authors: Yuancui Zhao, Lili Cui, Xing Xin Yang, Xingqian Sun, Yunkuan Liu, Zixian Yang, Liyuan Zhu, Chaorui Peng, Danye Li, Junfei Cai and Yunshu Ma

    Citation: BMC Complementary Medicine and Therapies 2021 21:284

    Content type: Research

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  45. We aimed to evaluate the effect of cranberry supplementation on serum liver enzymes, hepatic steatosis, and cardiometabolic risk factors in patients with non-alcoholic fatty liver (NAFLD).

    Authors: Kourosh Masnadi Shirazi, Elham Shirinpour, Arman Masnadi Shirazi and Zeinab Nikniaz

    Citation: BMC Complementary Medicine and Therapies 2021 21:283

    Content type: Research

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  46. Mucuna pruriens (L.) has been used for the treatment of several ailments in folkloric medicine. The present study therefore investigates the hepatoprotective and nephroprotective potentials of its leaves extract...

    Authors: Temidayo Ogunmoyole, Ayomide Micheal Ola-Awe and Omotola Grace Fatile

    Citation: BMC Complementary Medicine and Therapies 2021 21:282

    Content type: Research

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  47. Palmijihwanghwan (PJH) is a traditional medicine and eight constituents derived from PJH possess anti-inflammatory activities. However, the scientific evidence for its potential as a therapeutic agent for inflam...

    Authors: Eun Bok Baek, Jin-hyung Rho, Eunhye Jung, Chang-Seob Seo, Jin-Hee Kim and Hyo-Jung Kwun

    Citation: BMC Complementary Medicine and Therapies 2021 21:281

    Content type: Research

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  48. Garcinia subelliptica Merr. is a multipurpose coastal tree, the potential medicinal effects of which have been studied, including cancer suppression. Here, we present evidence that the ethanol extract of G. subel...

    Authors: Kyun Ha Kim, Ji Yeon Lee, Wan Yi Li, Sangwoo Lee, Han-Sol Jeong, Jun-Yong Choi and Myungsoo Joo

    Citation: BMC Complementary Medicine and Therapies 2021 21:280

    Content type: Research

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  49. Obesity prevalence has increased during the past few decades, causing a pandemic with an influx in other co-morbidities. Many factors influence weight gain in an obesogenic environment therefore strategies for...

    Authors: Ranil Jayawardena, Tormalli V. Francis, Sachith Abhayaratna and Priyanga Ranasinghe

    Citation: BMC Complementary Medicine and Therapies 2021 21:279

    Content type: Research article

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