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  1. Inflammatory bowel disease (IBD) is a severe digestive system condition, characterized by chronic and relapsing inflammation of the gastrointestinal tract. Scutellaria baicalensis Georgi (Huangqin, HQ) and Paeoni...

    Authors: Xiaoqi Huang, Zhiwei Chen, Minyao Li, Yaomin Zhang, Shijie Xu, Haiyang Huang, Xiaoli Wu and Xuebao Zheng

    Citation: BMC Complementary Medicine and Therapies 2020 20:292

    Content type: Research article

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  2. The balance between T helper 17 (Th17) cells and regulatory T cells (Tregs) is involved in immunological tolerance. Destruction of immunological tolerance by dendritic cell (DC)-mediated T cells is involved in...

    Authors: Jia Jia, Kai Zheng, Hong Shen, Jiangyi Yu, Ping Zhu, Shihai Yan, Yi Xu, Lei Zhu, Yuelin Lu, Peiqing Gu and Wan Feng

    Citation: BMC Complementary Medicine and Therapies 2020 20:291

    Content type: Research article

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  3. Diabetes and its related complications remain to be a major clinical problem. We aim to investigate the antidiabetic mechanistic actions of Plicosepalus Acaciae (PA) flowers in streptozotocin (STZ)-induced diabet...

    Authors: Mohamed-I Kotb El-Sayed, Shaza Al-Massarani, Ali El Gamal, Amina El-Shaibany and Hassan M Al-Mahbashi

    Citation: BMC Complementary Medicine and Therapies 2020 20:290

    Content type: Research article

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  4. In recent years, it has been reported that Qinbai Qingfei Concentrated Pellet (QQCP) has the effect of relieving cough and reducing sputum. However, the therapeutic potentials of QQCP on post-infectious cough ...

    Authors: Weigang Jia, Wei Wang, Rui Li, Quanyu Zhou, Ying Qu, Yumei Jia, Zhiheng Zhang, Chengwei Wan and Wanwan Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:289

    Content type: Research article

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  5. Candidiasis, an opportunistic cosmopolitan disease is nowadays like bacterial infections which is a real public health problem. In view of the emergence of Candida strains resistant to existing antifungal agen...

    Authors: Brice Armand Fanou, Jean Robert Klotoe, Lauris Fah, Victorien Dougnon, Charles Hornel Koudokpon, Ghislaine Toko and Frédéric Loko

    Citation: BMC Complementary Medicine and Therapies 2020 20:288

    Content type: Research article

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  6. The leaf of Anacardium occidentale L. has been a component of many herbal recipes in South-Western Nigeria. The work reported herein, therefore, explored the phytochemical composition of this plant and the potent...

    Authors: Bamigboye J. Taiwo, Temidayo D. Popoola, Fanie R. van Heerden and Amos A. Fatokun

    Citation: BMC Complementary Medicine and Therapies 2020 20:287

    Content type: Research article

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  7. MicroRNAs (miRNAs) play vital roles in acute inflammatory and antiviral responses during influenza A virus (IAV) infection. The Xijiao Dihuang decoction combined with Yinqiao powder (XDY) is applied to remedy ...

    Authors: Ke Li, Xiaoming Chen, Jing Zhong, Hehe Ye, Shujing Zhang, Dongyu Ge, Xudan Wang and Ying Wu

    Citation: BMC Complementary Medicine and Therapies 2020 20:286

    Content type: Research article

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  8. Dysmenorrhea is a common problem that affects female students’ quality of life and academic activities. Complementary and alternative therapies (CATs) are used for the treatment of dysmenorrhea. This study inv...

    Authors: Usman Abubakar, Amni Izzati Zulkarnain, Fatihah Samri, Sabrina Ros Hisham, Anis Alias, Muhammad Ishak, Hajarah Sugiman and Taufik Ghozali

    Citation: BMC Complementary Medicine and Therapies 2020 20:285

    Content type: Research article

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  9. Millions of people are suffering from chronic pain conditions, such as headache, arthritis, cancer. Apart from western medicines, traditional Chinese medicines are also well accepted for pain management, espec...

    Authors: Bobin Mi, Qiushi Li, Tong Li, Jessica Marshall and Jiayang Sai

    Citation: BMC Complementary Medicine and Therapies 2020 20:284

    Content type: Research article

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  10. A novel extract of mulberry leaves fermented with Cordyceps militaris (EMfC) is reported to exert anti-obesity activity, although their molecular mechanism during hepatic steatosis has not verified.

    Authors: Mi Rim Lee, Ji Eun Kim, Ji Won Park, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Young Whan Choi, Kyung Mi Kim, Jin Tae Hong and Dae Youn Hwang

    Citation: BMC Complementary Medicine and Therapies 2020 20:283

    Content type: Research article

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  11. Alzheimer’s disease (AD) is the most common cause of dementia in the elderly, characterized by a progressive and irreversible loss of memory and cognitive abilities. Currently, the prevention and treatment of ...

    Authors: Qihui Wu, Yunbo Chen, Yong Gu, Shuhuan Fang, Weirong Li, Qi Wang, Jiansong Fang and Chuipu Cai

    Citation: BMC Complementary Medicine and Therapies 2020 20:282

    Content type: Research article

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  12. Hyperuricemia is an independent risk factor in chronic kidney disease (CKD). Allopurinol and febuxostat are prescription medicines used to treat hyperuricemia but suffer side-effects. Earlier clinical study ha...

    Authors: Usharani Pingali, Chandrasekhar Nutalapati, Niranjan Koilagundla and Gangadhar Taduri

    Citation: BMC Complementary Medicine and Therapies 2020 20:281

    Content type: Research article

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  13. Yan Hou Qing (YHQ) is a Chinese medicinal formula designed to alleviate sore throat symptoms, but underlying mechanism of YHQ treatment for pharyngitis is poorly defined up to now.

    Authors: Min Xu, Tian-Yong Hu, Dong-Cai Li, Li Ma, Hua Zhang, Jun-Ting Fan, Xiao-Mei Fan, Xian-Hai Zeng, Shu-Qi Qiu, Zhi-Qiang Liu and Bao-Hui Cheng

    Citation: BMC Complementary Medicine and Therapies 2020 20:280

    Content type: Research article

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  14. Ginger or ginger extracts have been used in traditional medicine relieve pain caused by diarrhea predominant irritable bowel syndrome (IBS-D), but few data exists about its effectiveness. This present study wa...

    Authors: Changrong Zhang, Yongquan Huang, Peiwu Li, Xinlin Chen, Fengbin Liu and Qiuke Hou

    Citation: BMC Complementary Medicine and Therapies 2020 20:279

    Content type: Research article

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  15. Traditional medicine plays an important role in health care provision in the developing world. A number of cancer patients have been found to be using traditional medicine as primary therapy and/or as compleme...

    Authors: Patrick Rutendo Matowa, Mazuru Gundidza, Lovemore Gwanzura and Charles F. B. Nhachi

    Citation: BMC Complementary Medicine and Therapies 2020 20:278

    Content type: Research article

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  16. The present study was designed to examine the role of isoflavone genistein (GS) on bone formation, regulating oxidative stress and cell cycle in primary osteoblasts, as well as attenuation of osteoclast format...

    Authors: Sahabjada Siddiqui, Abbas Ali Mahdi and Md Arshad

    Citation: BMC Complementary Medicine and Therapies 2020 20:277

    Content type: Research article

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  17. In this study, Malus doumeri leaf flavonoids (MDLF) were used as the research object to observe their in vitro antioxidant stress ability. Hydrogen peroxide (H2O2) was used to induce oxidative stress in 293 T cel...

    Authors: Yanyan Li, Yunyi Li, Zhie Fang, Dan Huang, Yalin Yang, Dijia Zhao, Mingchun Hang and Junda Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:276

    Content type: Research article

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  18. Myrianthus arboreus P. Beauv. (Cecropiaceae) is a medicinal plant used to treat female infertility. The aqueous extract of M. arboreus leaves was found to improve the fertility of healthy female Wistar rats. In t...

    Authors: Marie Alfrede Mvondo, Flavie Ingrid Mzemdem Tsoplfack, Charline Florence Awounfack and Dieudonné Njamen

    Citation: BMC Complementary Medicine and Therapies 2020 20:275

    Content type: Research article

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  19. Schisandra chinensis (Turcz.) Baill bee pollen extract (SCBPE) is often used as a functional food in China due to its good antioxidant property. However, its chemical compositions and effects on H9c2 cardiomyocyt...

    Authors: Peiying Shi, Qianqian Geng, Lifu Chen, Tianyu Du, Yan Lin, Rongcai Lai, Fei Meng, Zhenhong Wu, Xiaoqing Miao and Hong Yao

    Citation: BMC Complementary Medicine and Therapies 2020 20:274

    Content type: Research article

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  20. The cytotoxicity of the root’s methanol extract of Imperata cylindrica (ICR). was previously reported in a panel of human cancer cell lines, including multi-drug resistant phenotypes. The aim of this study was to...

    Authors: Paul Nayim, Armelle T. Mbaveng, Arsene M. Ntyam and Victor Kuete

    Citation: BMC Complementary Medicine and Therapies 2020 20:273

    Content type: Research article

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  21. Medicinal plants have been used in the treatment of various ailments in most developing countries. Oral infections are the most prevalent diseases in man. The Rhus family has been found to have antimicrobial, ...

    Authors: Angela Mutuku, Lizzy Mwamburi, Lucia Keter, Joyce Ondicho, Richard Korir, James Kuria, Timothy Chemweno and Peter Mwitari

    Citation: BMC Complementary Medicine and Therapies 2020 20:272

    Content type: Research article

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  22. Human trichomoniasis, caused by the pathogenic parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually transmitted disease that contributes to reproductive morbidity in affected women and...

    Authors: Mendel Friedman, Christina C. Tam, Luisa W. Cheng and Kirkwood M. Land

    Citation: BMC Complementary Medicine and Therapies 2020 20:271

    Content type: Review

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  23. Fine dust penetrates deep into the human alveoli, and the fine dust accumulated in the bronchus and lungs can directly trigger various respiratory diseases. PM014 (HL301) is the herbal extract derived from the...

    Authors: Ye-Seul Lee, Daeun Min, Seon-Young Park, Junyoung Lee and Hyunsu Bae

    Citation: BMC Complementary Medicine and Therapies 2020 20:270

    Content type: Research article

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  24. This study aimed to explore the growth inhibitory effect of myricanol 5-fluorobenzyloxy ether (5FEM) and its underlying mechanisms in human lung adenocarcinoma A549 cells in vitro.

    Authors: Guan-hai Dai, Xuan Chen, Ze-ming Ren, Chen-jie Dai, Ye-ling Tong and Ke-qun Chai

    Citation: BMC Complementary Medicine and Therapies 2020 20:269

    Content type: Research article

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  25. Lead (Pb) is observed in all areas of the environment, mainly derived from human operations such as mining, processing, and burning fossil fuels. Pb toxicity is one of the most prevalent causes of human hepato...

    Authors: Nadia Z. Shaban, Samah A. Abdelrahman, Mohamed A. L. El-Kersh, Fayed A. K. Mogahed, Iman M. Talaat and Noha H. Habashy

    Citation: BMC Complementary Medicine and Therapies 2020 20:268

    Content type: Research article

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  26. Mutations in the human Ubiquilin 2 gene are associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) with or without frontotemporal dementia (FTD), the fatal neurodegenerative diseas...

    Authors: Patcharin Phokasem, Salinee Jantrapirom, Jirarat Karinchai, Hideki Yoshida, Masamitsu Yamaguchi and Panuwan Chantawannakul

    Citation: BMC Complementary Medicine and Therapies 2020 20:267

    Content type: Research article

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  27. Microbial infections are one of the major causes of death globally. This is attributed to the rising costs of primary healthcare and its inaccessibility especially in developing countries. Moreover, there has ...

    Authors: B. Ngobeni, S. S. Mashele, N. J. Malebo, E. van der Watt and I. T. Manduna

    Citation: BMC Complementary Medicine and Therapies 2020 20:266

    Content type: Research article

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  28. Ganluyin (GLY) is a famous classical prescription with a long history of use as a treatment for inflammatory conditions such as chronic pharyngitis (CP) in many parts of China. However, it has not been develop...

    Authors: Ye-Hui Chen, Rong Luo, Shan-Shan Lei, Bing Li, Fu-Chen Zhou, Hui-Ying Wang, Xue Chen, Xinglishang He, Yu-Zhi Wang, Liang-Hui Zhan, Ting-Ting Lu, Jie Su, Qiao-Xian Yu, Bo Li, Gui-Yuan Lv and Su-Hong Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:265

    Content type: Research article

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  29. The purpose of this study was to assess the antioxidative activity of selenium-enriched Chrysomyia Megacephala (Fabricius) (C. megacephala) larvae powder (SCML) and its impact on the diversity and structure of in...

    Authors: Dandan Xie, Liqin Jiang, Yao Lin and Zhenwei Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:264

    Content type: Research article

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  30. Atopic dermatitis (AD) is a worldwide chronic skin disease which burden public health. Sea buckthorn (SBT) (Hippophae rhamnoides L., Elaeagnaceae) oil, as a traditional herbal medicine, has been used for disease ...

    Authors: Xinxin Wang, Sijia Li, Jiping Liu, Dongning Kong, Xiaowei Han, Ping Lei, Ming Xu, Hongquan Guan and Diandong Hou

    Citation: BMC Complementary Medicine and Therapies 2020 20:263

    Content type: Research article

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  31. Triple-negative breast cancer (TNBC) is a kind of malignant tumor with higher recurrence and metastasis rate. According to historical records, the dry rhizomes Cyperus rotundus L. could be ground into powder and ...

    Authors: Shuangshuang Ma, Fukai Wang, Caijuan Zhang, Xinzhao Wang, Xueyong Wang and Zhiyong Yu

    Citation: BMC Complementary Medicine and Therapies 2020 20:262

    Content type: Research article

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  32. Dioscorea nipponica Makino is widely used in traditional Chinese medicine to treat gouty arthritis.

    Authors: Qi Zhou, Hui Juan Sun, Shu Min Liu, Xi Hong Jiang, Qiu Yue Wang, Shuang Zhang and Dong Hua Yu

    Citation: BMC Complementary Medicine and Therapies 2020 20:261

    Content type: Research article

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  33. African star apple (Chrysophyllum albidum) is a traditonal fruit, which is predominant in tropical regions with the fruit parts consumed by the populace and used in folklore to manage diabetes. However, the likel...

    Authors: Olubunmi B. Ajayi, Folake L. Oyetayo and Seun F. Akomolafe

    Citation: BMC Complementary Medicine and Therapies 2020 20:260

    Content type: Research article

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  34. The Sri Lankan traditional betel quid (TBQ) which had been extensively used in the country before its colonization is claimed to have antiperiodontopathic effects in the Sri Lankan folklore. However, there is ...

    Authors: Madhavi Priyanka Paranagama, Nadisha Sewwandi Piyarathne, Tharanga Lakmali Nandasena, Sumedha Jayatilake, Ayanthi Navaratne, Bandula Prasanna Galhena, Senani Williams, Jayantha Rajapakse and Kiyoshi Kita

    Citation: BMC Complementary Medicine and Therapies 2020 20:259

    Content type: Research article

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  35. Oral ulcer diseases are complex inflammatory diseases caused by multi-factors, which severely impact patient quality of life. Kouyanqing Granule (KYQG) has been used to treat inflammatory diseases of the mouth...

    Authors: Pan Chen, Hongliang Yao, Qing Yuan, Panlin Li, Xinning Wang, Weiwei Su, Yonggang Wang and Peibo Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:258

    Content type: Research article

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  36. Mulberry leaves are the dried leaves of Morus alba L., flavonoids from mulberry leaves (MLF) has showed regulatory effect on abnormal lipid metabolism, but the regulatory mechanism of MLF on cholesterol metabolis...

    Authors: Yucheng Hu, Jingqi Xu, Qian Chen, Mengyang Liu, Sijian Wang, Haiyang Yu, Yi Zhang and Tao Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:257

    Content type: Research article

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  37. Peganum harmala L. is a medicinal herb extensively used in traditional Chinese medicine (TCM). So far, relevant reports on the toxicity of Peganum harmala L. seeds (PHS) are hardly available. Especially, we still...

    Authors: Xiangzhen Miao, Xiao Zhang, Yanyan Yuan, Yali Zhang, Jian Gao, Nianxin Kang, Xinkui Liu, Jiarui Wu, Yonggang Liu and Peng Tan

    Citation: BMC Complementary Medicine and Therapies 2020 20:256

    Content type: Research article

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  38. Acori Tatarinowii Rhizome (ATR) is a well-recognized Chinese herbal medicine prescribed to treat neurological disorders. The essential oil (ATEO) is considered as the active fraction of ATR and the content of ...

    Authors: Lu Yan, Zhanzhan Liu, Li Xu, Yiyun Qian, Pingping Song and Min Wei

    Citation: BMC Complementary Medicine and Therapies 2020 20:255

    Content type: Research article

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  39. Primary insomnia (PI) is characterized by difficulties in initiating sleep or maintaining sleep, which lead to many serious diseases. Acupuncture for PI has drawn attention with its effectiveness and safety. H...

    Authors: Yu-Kai Wang, Tie Li, Li-Juan Ha, Zhong-Wen Lv, Fu-Chun Wang, Zhi-Hong Wang, Jing Mang and Zhong-Xin Xu

    Citation: BMC Complementary Medicine and Therapies 2020 20:254

    Content type: Research article

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  40. The prevalence and therapeutic effects of the use of herbal remedies for chronic liver diseases make the combined administration of herbal products with conventional treatment unable to be ignored. This study ...

    Authors: Tun-Pin Hsueh and Tung-Hu Tsai

    Citation: BMC Complementary Medicine and Therapies 2020 20:253

    Content type: Research article

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  41. Monoamine oxidase (MAO) A catalyzes oxidative deamination of monoamine neurotransmitters and dietary amines and regulates brain development and functions. Recently, we showed that MAO A mediates the progressio...

    Authors: Pei-Chuan Li, Shih-Yi Chen, Danzhou Xiangfei, Canquan Mao, Chieh-His Wu and Jean Chen Shih

    Citation: BMC Complementary Medicine and Therapies 2020 20:252

    Content type: Research article

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  42. Sulfated polysaccharides from marine algae are known to possess antioxidative activities, however, their therapeutic role in metal-induced neurodegeneration has not been explored. In this study, the neuroprote...

    Authors: Tosin A. Olasehinde, Ademola O. Olaniran and Anthony I. Okoh

    Citation: BMC Complementary Medicine and Therapies 2020 20:251

    Content type: Research article

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  43. Psoriasis is a common inflammatory skin disease. Abnormal proliferation of keratinocytes is one of the psoriatic histopathological features. Indirubin has an essential effect on the proliferation and activatio...

    Authors: Shou Gang Liu, Guang Pu Luo, Yong Bin Qu and Yong Feng Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:250

    Content type: Research article

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  44. Polycystic ovary syndrome (PCOS) is a common endocrine disorder. The aim of the present study was to evaluate the effects of the oral administration of thylakoid-rich spinach extract and the caraway aqueous ex...

    Authors: Saeed Sherafatmanesh, Maryam Ekramzadeh, Nader Tanideh, Mohammad-Taghi Golmakani and Farhad Koohpeyma

    Citation: BMC Complementary Medicine and Therapies 2020 20:249

    Content type: Research article

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  45. Chinese Medicine education is part of professional medical training in Hong Kong. An important element of this is herbal medicine, which requires both theoretical and practical knowledge. A field trip programm...

    Authors: Lei Li, Chi Wing Tam, Ning Wang, Fan Cheung, Qing Zhou, Cheng Zhang, Chien-shan Cheng, Lei Xiong and Yibin Feng

    Citation: BMC Complementary Medicine and Therapies 2020 20:248

    Content type: Research article

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  46. Self-care refers to a range of activities and approaches undertaken by an individual to maintain health and manage ill-health which may include various complementary or alternative approaches. The purpose of t...

    Authors: Karen Pilkington and Lisa Susan Wieland

    Citation: BMC Complementary Medicine and Therapies 2020 20:247

    Content type: Research article

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  47. Plant species from the genus Tecoma are found in tropical and subtropical regions around the world. Some of them are grown as ornamental plants and others can be used as medicinal plants. In the present study, et...

    Authors: Adriana Cotta Cardoso Reis, Breno Mello Silva, Hélia Maria Marques de Moura, Guilherme Rocha Pereira and Geraldo Célio Brandão

    Citation: BMC Complementary Medicine and Therapies 2020 20:246

    Content type: Research article

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  48. At present, ursodeoxycholic acid (UDCA) is internationally recognized as a therapeutic drug in clinic. However, about 40% Primary Biliary Cholangitis (PBC) patients are poor responders to UDCA. It has been dem...

    Authors: Hui Yang, Hang Yang, Lixia Wang, Honggang Shi, Bojia Liu, Xue Lin, Qingyong Chang, Jiande D. Z. Chen and Zhijun Duan

    Citation: BMC Complementary Medicine and Therapies 2020 20:242

    Content type: Research article

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  49. The use of Chinese herbal medicine (CHM) has been widely promoted as a natural and safe way to treat illness during pregnancy. However, prescription patterns and factors influencing its use are largely unknown...

    Authors: Shu-Hui Wen, Wei-Chuan Chang, Hsuan-Shu Shen and Hsien-Chang Wu

    Citation: BMC Complementary Medicine and Therapies 2020 20:240

    Content type: Research article

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  50. Stroke is one of the major causes of death and disability. The treatments that are provided to patients during hospitalization after an acute stroke are very important in stabilizing their medical condition an...

    Authors: Wei-Sen Chen, Hung-Chih Hsu, Yi-Wen Chuang, Meng Lee, Kuan-Yu Lu, Yi-Fei Chen and Chien-Min Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:244

    Content type: Research article

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