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  1. Traditional Korean Medicine (TKM) is highly integrated with the modern health care system of South Korea and is actively used in the public health field. Since 2014, the Ministry of Health and Welfare of South...

    Authors: Eunhye Hyun, Jiseon Ryu, Kibong Kim, Sangjae Lee, Seungtae Kim and Byungmook Lim
    Citation: BMC Complementary Medicine and Therapies 2022 22:175
  2. Polysaccharides from wampee have been reported to process various biological activities, while the relationship between structure and bioactivities has been barely addressed. Pectin, an abundant water-soluble ...

    Authors: Weiyu Fu, Xuehua Liao, Qian Zhang, Yuzhen Zhu, Si Mei, Qian Li, Xin Zhou, Xiaojun Li, Hui Luo, Hua Ye and Kefeng Wu
    Citation: BMC Complementary Medicine and Therapies 2022 22:174
  3. Conventional cancer treatments, such as chemotherapy, radiation therapy, and surgery, often affect the patients’ quality of life due to their serious side effects, indicating the urgent need to develop less to...

    Authors: Mahla Amirzadeh, Sara Soltanian and Neda Mohamadi
    Citation: BMC Complementary Medicine and Therapies 2022 22:173
  4. Globally, ischemic stroke is a major health threat to humans that causes lifelong disability and death. Mentha arvensis (MA) has been used in traditional medicine to alleviate oxidative stress and inflammation-re...

    Authors: Md Sadikul Islam, Ha-Young Shin, Yeo-Jin Yoo, Eui-Yong Lee, Ryunhee Kim, Young-Jin Jang, Md Rashedunnabi Akanda, Hyun-Jin Tae, In-Shik Kim, Dongchoon Ahn and Byung-Yong Park
    Citation: BMC Complementary Medicine and Therapies 2022 22:172
  5. Psychologists, and their clients, are engaging with complementary medicine (CM). Increasing evidence for CM approaches, such as improved nutrition and St John’s wort, has led to their inclusion in the Royal Au...

    Authors: Carrie Thomson-Casey, Jon Adams and Erica McIntyre
    Citation: BMC Complementary Medicine and Therapies 2022 22:171
  6. Busulfan is an antineoplastic medication that is broadly utilized for cancer treatment. It affects the testicular function and leads to sterility. The present study aimed to evaluate the effects of ellagic aci...

    Authors: Amirabbas Rostami, Sina Vakili, Farhad Koohpeyma, Bahia Namavar Jahromi, Ziba Afshari Aghajari, Fatemeh Mahmoudikohani, Forough Saki, Marzieh Mahmoodi, Khojaste Rahimi Jaberi, Ahmad Movahedpour, Majid Jafari Khorchani and Saam Noroozi
    Citation: BMC Complementary Medicine and Therapies 2022 22:170
  7. Pithecellobium dulce (Roxb.), an evergreen medium-sized, spiny tree which have vast nutritional values and widely used in ayurvedic medicines and home remedies. The plant has also been a rich source of biological...

    Authors: Masuma Akter, Mst. Shahnaj Parvin, Md. Mahadi Hasan, Md. Aziz Abdur Rahman and Md. Ekramul Islam
    Citation: BMC Complementary Medicine and Therapies 2022 22:169
  8. Current therapies for alcohol-induced liver injury are of limited efficacy and associated with significant side effects. With the proposed pathophysiology of alcohol-induced liver injury to be related to deran...

    Authors: Maneerat Chayanupatkul, Kanjana Somanawat, Natthaya Chuaypen, Naruemon Klaikeaw, Natcha Wanpiyarat, Prasong Siriviriyakul, Somying Tumwasorn and Duangporn Werawatganon
    Citation: BMC Complementary Medicine and Therapies 2022 22:168
  9. Vascular damage, autoimmune abnormalities, and fibrosis are the three pathological features of systemic sclerosis (SSc).However, pulmonary vascular damage is the main factor affecting the progression and progn...

    Authors: Kai Li, Qian Wang, Qin Lv, Kelei Guo, Li Han, Peipei Duan, Yongzheng Deng and Hua Bian
    Citation: BMC Complementary Medicine and Therapies 2022 22:167
  10. Ginsenoside Rg-1 (Rg-1), a triterpenoid saponin abundantly present in Panax ginseng, is a type of naturally occurring steroid with known anti-diabetic and anti-inflammatory effects. In this study, we sought to co...

    Authors: A Young Han, Su Min Ha, You Kyoung Shin and Geun Hee Seol
    Citation: BMC Complementary Medicine and Therapies 2022 22:166
  11. Vitamin D (Vit D) supplementation and Aerobic Training (AT) exert several beneficial effects such as antioxidant and anti-inflammatory actions. The literature on the effects of AT and Vit D supplementation on ...

    Authors: Rastegar Hoseini, Hiwa Ahmed Rahim and Jalal Khdhr Ahmed
    Citation: BMC Complementary Medicine and Therapies 2022 22:165
  12. Influenza A virus infection due to drug resistance and side effects of the conventional antiviral drugs yet remains a serious public health threat for humans and animals. Forsythiaside A is an effective ingred...

    Authors: Xiao Zheng, Ziqi Chen, Shanshan Shi, Huijun Yan, Junmei Zhou, Lifang Jiang, Hongli Wang, Guanghui Hou and Zhenyou Jiang
    Citation: BMC Complementary Medicine and Therapies 2022 22:164
  13. Previous studies in our laboratory in ex vivo assays have demonstrated H. hemerocallidea extract as potential antidiabetic agent through increased insulin release from pancreatic beta cells. Thus, for this study ...

    Authors: N. M. Mkolo, O. O. Olaokun, P. H. King, I. Janse van Rensburg, J. N. Eloff and V. Naidoo
    Citation: BMC Complementary Medicine and Therapies 2022 22:163
  14. In Korea, conventional medicine (CM) and traditional Korean medicine (KM) are run as a dual healthcare system; however, the backgrounds and characteristics of the users of both medical services have not yet be...

    Authors: Yui Sasaki, Jeong-Su Park, Sunju Park, Chunhoo Cheon, Yong-Cheol Shin, Seong-Gyu Ko and Bo-Hyoung Jang
    Citation: BMC Complementary Medicine and Therapies 2022 22:162
  15. In 2019, investigators from China, South Korea and the United States of America initiated a coordinated multinational trial. The trial included three parallel randomized studies with a planned pooled analysis ...

    Authors: Sylvia Baedorf Kassis, Weidong Lu, Sarah A. White, Im Hee Shin, Sung Hwan Park, Young Ju Jeong, Chang Yao, Jennifer Ligibel and Barbara E. Bierer
    Citation: BMC Complementary Medicine and Therapies 2022 22:161
  16. The present study aimed to determine the protective effects of hypaconitine (HA) and glycyrrhetinic acid (GA) against chronic heart failure (CHF) in the rats and to explore the underlying molecular mechanisms.

    Authors: Liqin Wang, Haiming Deng, Tengyu Wang, Yun Qiao, Jianbing Zhu and Mingfeng Xiong
    Citation: BMC Complementary Medicine and Therapies 2022 22:160
  17. Croton macrostachyus is an important plant in traditional African medicine, widely utilized to treat a variety of diseases. In Kenya, HIV-infected patients use leaf and root decoctions of the plant as a cure for...

    Authors: Ermias Mergia Terefe, Faith A. Okalebo, Solomon Derese, Moses K. Langat, Eduard Mas-Claret, Nada H. Aljarba, Saad Alkahtani, Gaber El-Saber Batiha, Arabinda Ghosh, Eman A. El-Masry and Joseph Muriuki
    Citation: BMC Complementary Medicine and Therapies 2022 22:159
  18. The 7β-(3-ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN), a sesquiterpenoid isolated from the Tussilago farfara Linneaus (Asteraceae), was evaluated against acute Carrageenan...

    Authors: Amna Khan, Li Zhang, Chang Hu Li, Ashraf Ullah Khan, Bushra Shal, Adnan Khan, Sajjad Ahmad, Fakhar ud Din, Zia ur rehman, Feng Wang and Salman Khan
    Citation: BMC Complementary Medicine and Therapies 2022 22:158
  19. Hypertension and its associated dysfunction of the blood-brain barrier (BBB) are considered to contribute to cerebral small vessel disease (cSVD). Angiotensin II (Ang II), as an important vasoactive peptide of...

    Authors: Yu Yan Xie, Yun Wei Lu and Gu Ran Yu
    Citation: BMC Complementary Medicine and Therapies 2022 22:157
  20. Despite the number of deaths and the significant economic and social costs associated with Chagas, Leishmaniasis and Malaria diseases worldwide, available drugs are limited and have serious side effects and hi...

    Authors: Camila M. Clemente, Sara M. Robledo and Soledad Ravetti
    Citation: BMC Complementary Medicine and Therapies 2022 22:156
  21. Individual acupuncture (AP) is a safe and effective treatment for cancer-related pain and other symptoms in cancer survivors. However, access to individual AP is limited, and costs can be prohibitive. Group AP...

    Authors: Devesh Oberoi, Erica N. Reed, Katherine-Ann Piedalue, Jessa Landmann and Linda E. Carlson
    Citation: BMC Complementary Medicine and Therapies 2022 22:155
  22. The study was planned to investigate the phytochemicals, antidiabetic and antioxidant studies of A. consanguineum.

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Ali O. Alqarni, Bandar A. Alyami, Omaish S. Alqahtani, Muhammad Saeed Jan, Fida Hussain, Zia Ul Islam, Farhat Ullah, Muhammad Ayaz, Muhammad Abbas, Umer Rashid and Abdul Sadiq
    Citation: BMC Complementary Medicine and Therapies 2022 22:154
  23. Gout is a common disease with high incidence due to unhealthy diet and living habits. Simiao Powder, as a classic formula consisted of four common herbs, has been widely used in clinical practice since ancient...

    Authors: Huachong Xu, Jialin Wu, Shiqi Wang, Lu Xu, Pei Liu, Yucong Shi, Sizhi Wu, Li Deng and Xiaoyin Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:152
  24. Asthma and idiopathic pulmonary fibrosis (IPF) are common chronic diseases of the respiratory system in clinical practice. However, the relationship and molecular links remain unclear, and the current treatmen...

    Authors: Yuanyuan Zhong, Lingli Hu, Wenjing Chen, Bin Wang, Jing Sun and Jingcheng Dong
    Citation: BMC Complementary Medicine and Therapies 2022 22:151
  25. Endometrial carcinoma is one of the two cancers with rising mortality and morbidity in recent years. In the light of many controversies about its treatment, it is urgent to construct a new prognostic model and...

    Authors: Zhiheng Lin, Xiaohui Sui, Wenjian Jiao, Ying Wang and Junde Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:150
  26. Antimicrobial peptides (AMPs) are important effectors of the innate defense system. Cathelicidins, (CRAMP in mouse/rat, LL-37 in human) is one of the two major classes of AMPs in humans. The upregulation of LL...

    Authors: Nagat Siednamohammeddeen, Rehab Badi, Tahane Mohammeddeen, Khalid Enan and AmalSaeed
    Citation: BMC Complementary Medicine and Therapies 2022 22:149
  27. Massage is a widely acceptable and popular form of complementary medicine (CM) among Australian women. While there is some research that reports on massage use in younger women, there is minimal research explo...

    Authors: Suzy Ladanyi, Jon Adams and David Sibbritt
    Citation: BMC Complementary Medicine and Therapies 2022 22:148
  28. Gao-Zi-Yao has long been a unique way for treating various diseases. The present study is to explore the effect of Gao-Zi-Yao on learning and memory function in old spontaneous hypertensive rats (SHR) and its ...

    Authors: Meng-Xiao Han, Wen-Yi Jiang, Yan Jiang, Lin-Hui Wang, Rong Xue, Guo-Xing Zhang and Jing-Wei Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:147
  29. Herbal medicines are widely used in the world especially in developing countries. Pregnant women use herbal products to treat pregnancy related illnesses due to prior experience of herbal medicine use and easy...

    Authors: Yaschilal Muche Belayneh, Tewodros Yoseph and Solomon Ahmed
    Citation: BMC Complementary Medicine and Therapies 2022 22:146
  30. Use of natural products has been proposed as an efficient method in modulation of immune system and treatment of cancers. The aim of this study was to investigate the potential of cryptotanshinone (CPT), narin...

    Authors: Shokoofe Noori, Mitra Nourbakhsh, Hossein Imani, Niloofar Deravi, Niloufar Salehi and Zohreh Abdolvahabi
    Citation: BMC Complementary Medicine and Therapies 2022 22:145
  31. Chronic exposure to ultraviolet B (UVB) causes a series of adverse skin reactions, such as erythema, sunburn, photoaging, and cancer, by altering signaling pathways related to inflammation, oxidative stress, a...

    Authors: Bei Chen, Honghong Chen, Haidong Qu, Kun Qiao, Min Xu, Jingna Wu, Yongchang Su, Yan Shi, Zhiyu Liu and Qin Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:144
  32. Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum) essential oils are two medicinally important plant-derived substances with a wide range of biological properties. Besides, nanoemulsion-based gels ...

    Authors: Fariba Esmaeili, Masoumeh Zahmatkeshan, Yaser Yousefpoor, Hiva Alipanah, Ehsan Safari and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:143
  33. The potential of essential oils (EOs) and of their principal constituents for eradication of biofilm and at the same time the research of new potential acetylcholinesterase inhibitors is gaining increasing int...

    Authors: Lucia Caputo, Francesca Capozzolo, Giuseppe Amato, Vincenzo De Feo, Florinda Fratianni, Giovanni Vivenzio and Filomena Nazzaro
    Citation: BMC Complementary Medicine and Therapies 2022 22:142
  34. Diabetic retinopathy (DR), one of the most common and severe microvascular complication of diabetes mellitus (DM), is mainly caused by diabetic metabolic disorder. So far, there is no effective treatment for D...

    Authors: Yao Chen, Jiaojiao Sun, Zhiyun Zhang, Xiaotong Liu, Qiaozhi Wang and Yang Yu
    Citation: BMC Complementary Medicine and Therapies 2022 22:141

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:153

  35. Mosquito-borne diseases such as malaria and encephalitis are still the cause of several hundred thousand deaths annually. The excessive use of chemical insecticides for transmission control has led to environm...

    Authors: Alireza Sanei-Dehkordi, Mohammad Djaefar Moemenbellah-Fard, Mostafa Saffari, Elham Zarenezhad and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:140
  36. Crinum latifolium L. (Amaryllidaceae) has been used in Southeast Asian traditional medicine to alleviate the symptoms of benign prostatic hyperplasia (BPH). The pathological mechanism of BPH is associated with th...

    Authors: Wisuwat Thongphichai, Tamonwan Uttarawichien, Pithi Chanvorachote, Supaporn Pitiporn, Todsaphol Charoen-ame, Pakakrong Kwankhao, Pasarapa Towiwat and Suchada Sukrong
    Citation: BMC Complementary Medicine and Therapies 2022 22:139
  37. Alleviating suffering and improving quality of life are universally shared goals. In this context, we implemented a pilot study to assess the feasibility and acceptability of a mindfulness intervention in the ...

    Authors: Virginie Prevost, Sophie Lefevre-Arbogast, Alexandra Leconte, Claire Delorme, Sandrine Benoit, Titi Tran and Bénédicte Clarisse
    Citation: BMC Complementary Medicine and Therapies 2022 22:138
  38. Cancer-related incidence and mortality rates are rapidly increasing worldwide. However, no studies have examined the effect of cancer as a single factor on the use of traditional, complementary, and alternativ...

    Authors: Dongsu Kim, Soo-Hyun Sung, Seungwon Shin and Minjung Park
    Citation: BMC Complementary Medicine and Therapies 2022 22:137
  39. Authors: Hei-Jen Huang, Jie-Ling Chen, Jian-Fu Liao, Yu-Hsin Chen, Min-Wei Chieu, Ya-Yun Ke, Chih-Chieh Hsu, Ying-Chieh Tsai and Hsiu Mei Hsieh-Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:136

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:259

  40. Trachyspermum ammi, commonly known as Ajwain, is a member of the Apiaceae family. It is a therapeutic herbal spice with diverse pharmacological properties, used in traditional medicine for various ailments. Howev...

    Authors: Saud O. Alshammari, Taibah Aldakhil, Qamar A. Alshammari, David Salehi and Aftab Ahmed
    Citation: BMC Complementary Medicine and Therapies 2022 22:135
  41. The genus Eryngium is a member of the Apiaceae family that has shown different pharmacological effects mainly including anti-inflammatory, analgesic, anti-cancer, hepatoprotective, and anti-oxidant. Previous r...

    Authors: Haleh Forouhandeh, Zahra Rezaei Param, Ommoleila Molavi, Parina Asgharian and Vahideh Tarhriz
    Citation: BMC Complementary Medicine and Therapies 2022 22:134
  42. The blood-testis barrier (BTB) is a physical barrier of the testis to prevent various exogenous substrates from entering apical compartments and provides immune privilege for spermatogenesis, which is essentia...

    Authors: Junjun Li, Yaodong You, Peihai Zhang, Xiaopeng Huang, Liang Dong, Fang Yang, Xujun Yu and Degui Chang
    Citation: BMC Complementary Medicine and Therapies 2022 22:133
  43. Cordyceps species have been used as tonics to enhance energy, stamina, and libido in traditional Asian medicine for more than 1600 years, indicating their potential for improving reproductive hormone disorders an...

    Authors: Dongyeop Jang, Eunjoo Lee, Sullim Lee, Yongsam Kwon, Ki Sung Kang, Chang-Eop Kim and Daeyoung Kim
    Citation: BMC Complementary Medicine and Therapies 2022 22:132
  44. Cognitive health is of great interest to society, with neuroinflammation and systemic inflammation age-related risk factors that are linked to declines in cognitive performance. Several botanical ingredients h...

    Authors: Gemma Margetts, Sotirios Kleidonas, Nawel S. Zaibi, Mohamed S. Zaibi and Kieron D. Edwards
    Citation: BMC Complementary Medicine and Therapies 2022 22:131
  45. Medicinal plants have been successfully used as an alternative source of drugs for the treatment of microbial diseases. Finding a novel treatment for malaria is still challenging, and various extracts from dif...

    Authors: Ahmed M. Abdou, Abdel-latif S. Seddek, Noha Abdelmageed, Mohamed O. Badry and Yoshifumi Nishikawa
    Citation: BMC Complementary Medicine and Therapies 2022 22:130
  46. Jianpi Qinghua Fomula (JPQHF), a clinically proven prescription,has been applied to cure insulin resistance(IR) and type 2 diabetes (T2DM) for more than 20 years. Here, we will unravel the underlying molecular...

    Authors: Yahua Liu, Xu Han, Mengjie Cai, Shenyi Jin, Zihui Yan, Hao Lu and Qingguang Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:129
  47. Complementary and alternative medicine (CAM) is defined as a group of diverse medical and healthcare practices outside of conventional medicine modalities. The use of CAM is steadily increasing despite gaps in...

    Authors: Brittany R. Odegard, Mollie R. Ferguson, Farah Naja, Jennifer Ayoub and Jinan Banna
    Citation: BMC Complementary Medicine and Therapies 2022 22:128
  48. Home remedies are anchored in patients’ everyday life, but their use in Western cultures remains scarcely explored. Our objectives were to investigate primary care patients’ perspectives and use of non-pharmac...

    Authors: Neria E. Winkler, Paul Sebo, Dagmar M. Haller and Hubert Maisonneuve
    Citation: BMC Complementary Medicine and Therapies 2022 22:126
  49. The current drug treatments for benign prostatic hyperplasia (BPH) have negative side effects. Therefore, it is important to find effective alternative therapies with significantly fewer side effects. Our prev...

    Authors: Guifang Huang, Xiao He, Zesheng Xue, Yiming Long, Jiakuan Liu, Jinming Cai, Pengfei Tang, Bangmin Han, Bing Shen, Ruimin Huang and Jun Yan
    Citation: BMC Complementary Medicine and Therapies 2022 22:125