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  1. Scientists and medical professionals are actively striving to improve the efficacy of treatment methods for oral squamous cell carcinoma (OSCC), the most frequently occurring cancer within the oral cavity, by ...

    Authors: Maryam Koopaie, Hanieh Karimi, Mohammad Sohrabi and Hooman Norouzi
    Citation: BMC Complementary Medicine and Therapies 2023 23:296
    Content type: Research Published on:

  2. Saikosaponin A (SSA) shows a series of pharmacological activities, such as anti-inflammatory, antioxidant and antitumor. However, there is a lack of comprehensive research or sufficient evidence regarding the ...

    Authors: Chao Wang, Ruijuan Zhang, Xu Chen, Mengyun Yuan, Jian Wu, Qingmin Sun, Chunrun Miao and Yali Jing
    Citation: BMC Complementary Medicine and Therapies 2023 23:295
    Content type: Research Published on:

  3. Amyloid-β1-42 (Aβ1-42) plays an essential role in the development of the early stage of Alzheimer’s disease (AD). Asiatic acid (AA), an active compound in Centella asiatica L, exhibit neuroprotective properties i...

    Authors: Ridho Islamie, Su Lwin Lwin Myint, Tissana Rojanaratha, Garnpimol Ritthidej, Oraphan Wanakhachornkrai, Onsurang Wattanathamsan and Ratchanee Rodsiri
    Citation: BMC Complementary Medicine and Therapies 2023 23:294
    Content type: Research Published on:

  4. Breast cancer is a prevalent malignant tumor that affects women worldwide. The primary challenge in treating breast cancer is combating drug resistance, which contributes to relapse and metastasis. Jatrophone ...

    Authors: Khawlah Shari, Rania A. El Gedaily, Rasha M. Allam, Khaled M. Meselhy, Amal E. Khaleel and Essam Abdel-Sattar
    Citation: BMC Complementary Medicine and Therapies 2023 23:293
    Content type: Research Published on:

  5. Adherence to healthy lifestyle recommendations has positive effects on cancer outcomes yet adherence is low among cancer survivors. Differences in adherence between women and men, phase of survivorship, and ot...

    Authors: Kiwumulo Nakandi, Faith O. Benebo, Laila A. Hopstock, Trine Stub and Agnete E. Kristoffersen
    Citation: BMC Complementary Medicine and Therapies 2023 23:292
    Content type: Research Published on:

  6. “Rhubarb-Peach Kernel” herb pair (RP) one of the most frequently used drug pairs, has been used in traditional medicine in China to treat inflammation and diseases associated with pain. Although it is widely u...

    Authors: Zi Liao, Ya Lei, Li Peng, Xianyun Fu, Wei Wang and Dan Yang
    Citation: BMC Complementary Medicine and Therapies 2023 23:291
    Content type: Research Published on:

  7. Cervical cancer remains a significant global health issue, highlighting the need for effective therapeutic strategies. Given that Sphaerocoryne affinis (SA) has shown potential anti-cancer activity in several can...

    Authors: Nghia Le-Trung, Tue Minh Duong, Thao Thi Phuong Dang and Kaeko Kamei
    Citation: BMC Complementary Medicine and Therapies 2023 23:290
    Content type: Research Published on:

  8. Panax quinquefolius saponin (PQS) was shown beneficial against platelet adhesion and for gastroprotection. This study aimed to investigate the integrated efficacy of PQS with dual antiplatelet therapy (DAPT) on p...

    Authors: Wenting Wang, Lei Song, Lin Yang, Changkun Li, Yan Ma, Mei Xue and Dazhuo Shi
    Citation: BMC Complementary Medicine and Therapies 2023 23:289
    Content type: Research Published on:

  9. Non-alcoholic fatty liver disease (NAFLD) has been well defined as a common chronic liver metabolism disorder. Statins as a first-line therapeutic treatment had some side effects. Here, we found that Fumigacla...

    Authors: Wanguo Yu, Yaxin Gao, Zaoya Zhao, Xiufeng Long, Yi Yi and Shuo Ai
    Citation: BMC Complementary Medicine and Therapies 2023 23:288
    Content type: Research Published on:

  10. Diabetic Nephropathy (DN) is a serious complication of diabetes, the diagnosis and treatment of DN is still limited. Sinomenine (SIN) is an active extract of herbal medicine and has been applied into the thera...

    Authors: Yan Li, Lei Wang, Jimin Zhang, Bojun Xu and Huakui Zhan
    Citation: BMC Complementary Medicine and Therapies 2023 23:287
    Content type: Research Published on:

  11. Tea (Camellia sinensis L.) flowers will compete with tea leaves in nutrition and are abandoned as an undesirable by-product. In this study, the biological efficacy of tea flowers was investigated. Further explora...

    Authors: Fangfang Chen, Yu-Pei Chen, Hongtan Wu, Ya Li, Shudi Zhang, Jincheng Ke and Jeng-Yuan Yao
    Citation: BMC Complementary Medicine and Therapies 2023 23:286
    Content type: Research Published on:

  12. In respect of the WHO’s commendation to incorporate traditional medicine (TM) in health care, the Cameroon government wants to promote the use of the traditional medicine and is resolute on encouraging the tre...

    Authors: Abenwie Suh Nchang, Sylvia Njong, Sandra Fankem Noukimi, Lahngong Methodius Shinyuy, Sylvie Bambara, Edgar M. Kalimba, Joseph Kamga, Jacob Souopgui, Stephen Mbigha Ghogomu, Michel Frederich, Jean Lesort Louck Talom and Annie Robert
    Citation: BMC Complementary Medicine and Therapies 2023 23:285
    Content type: Research Published on:

  13. The energy metabolism of drug-resistant tumor cells can provide a survival advantage during therapy, and treatment itself may influence metabolic reprogramming. Petiveria alliacea (Traditional name: Anamu) could ...

    Authors: Ricardo Ballesteros-Ramírez, Paola Pinilla, Jesús Sanchéz, Mónica Arévalo, Elio Sanchez, Pablo Aschner, Claudia Urueña and Susana Fiorentino
    Citation: BMC Complementary Medicine and Therapies 2023 23:284
    Content type: Study Protocol Published on:

  14. The Biarum species (Kardeh) has been consumed as a traditional functional food and medicine for decades. The current study investigates the phytochemistry, in-vitro and in-vivo bioactivities of methanol extracts ...

    Authors: Bassam Ali Abed Wahab, Zaenah Zuhair Alamri, Ahmed A.j. Jabbar, Ibrahim Abdel Aziz Ibrahim, Riyad A. Almaimani, Hussain A. Almasmoum, Mazen M. Ghaith, Wesam F. Farrash, Yahya A. Almutawif, Khalid Aidarous Ageeli, Soliman Mohammed Alfaifi and Rahaf Frehan Alharthi
    Citation: BMC Complementary Medicine and Therapies 2023 23:283
    Content type: Research article Published on:

  15. Hypertension is among the risk factors of death globally. Novel antihypertensive peptides are alternative choices of antihypertensive assistance. This study aimed to discover novel antihypertensive peptides fr...

    Authors: Pattaneeya Prangthip, Watanalai Panbangred and Onrapak Reamtong
    Citation: BMC Complementary Medicine and Therapies 2023 23:282
    Content type: Research Published on:

  16. Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously rep...

    Authors: Shota Kajiyama, Takahiro Nagatake, Satoru Ishikawa, Koji Hosomi, Yuki Shimada, Yasunori Matsui and Jun Kunisawa
    Citation: BMC Complementary Medicine and Therapies 2023 23:281
    Content type: Research Published on:

  17. About 20–40% of people with Heart failure (HF) suffer from some depression, which is 4–5% greater than the overall population. This depression can lead to undesirable outcomes, including elevated mortality rat...

    Authors: Mahmoud Balata, Mohamed Ibrahim Gbreel, Asmaa Ahmed Elrashedy, Ralf Westenfeld, Roman Pfister, Sebastian Zimmer, Georg Nickenig, Marc Ulrich Becher and Atsushi Sugiura
    Citation: BMC Complementary Medicine and Therapies 2023 23:280
    Content type: Research Published on:

  18. Population based studies have shown large differences in the estimated prevalence of complementary and integrative health (CIH) usage between studies. This is in part due to there being no golden standard defi...

    Authors: Maija Pyykkönen, Pauliina Aarva, Salla Ahola, Matti Pasanen and Kaija Helin
    Citation: BMC Complementary Medicine and Therapies 2023 23:279
    Content type: Research Published on:

  19. Migraine is a neurological disease characterized by moderate to severe headache and various neurological symptoms. It is often cause mood and anxiety disorders that can seriously affect quality of life. Acupun...

    Authors: Zhao Li, Jie Feng, Shao Yin, Xin Chen, Qicheng Yang, Xu Gao, Deya Che, Li Zhou, Hui Yan, Yue Zhong and Fengya Zhu
    Citation: BMC Complementary Medicine and Therapies 2023 23:278
    Content type: Research Published on:

  20. The scientific community is concerned about cardiovascular disease mortality and morbidity, especially myocardial infarction (MI). Schisantherin A (SCA), a dibenzocyclooctadiene lignan monomer found in S. chinens...

    Authors: Xiaolong Mi, Zhijun Zhang, Jinfang Cheng, Zheng Xu, Kaiyi Zhu and Yunxia Ren
    Citation: BMC Complementary Medicine and Therapies 2023 23:277
    Content type: Research Published on:

  22. Telemedicine includes the delivery of health-care services and sharing of health information across distances. Past research has found that telemedicine can play a role in enhancing complementary, alternative,...

    Authors: Aimun Qadeer Shah, Noella Noronha, Robert Chin-See, Christina Hanna, Zeest Kadri, Amn Marwaha, Neetu Rambharack and Jeremy Y. Ng
    Citation: BMC Complementary Medicine and Therapies 2023 23:275
    Content type: Research Published on:

  23. Fascial Therapy is an ancient and widespread practice throughout the world. These approaches are very common in osteopathic practice and taught in workshops for professionals from different areas of health car...

    Authors: Fabiana C. da Silva, Leonardo S. Vieira, Lucas V. Santos, Nathaly Gaudreault, Ronaldo H. Cruvinel-Júnior and Gilmar M. Santos
    Citation: BMC Complementary Medicine and Therapies 2023 23:274
    Content type: Research Published on:

  24. Xanthii Fructus was used in the treatment of rhinitis and related nasal disease. It is the most commonly used chemically active component in compounds formulated for the treatment of rhinitis. However, poisoni...

    Authors: Yaqian Li, Guangcai Yu, Longke Shi, Liwen Zhao, Zixin Wen, Baotian Kan and Xiangdong Jian
    Citation: BMC Complementary Medicine and Therapies 2023 23:273
    Content type: Case report Published on:

  25. The present study aimed to evaluate the effect of the ethyl acetate fraction of P. reptans root (PEF) preconditioning on expressions of lncRNAs H19 and MIAT in H9C2 myoblasts I/R injury.

    Authors: Hassan Mirzaei, Aref Salehi, Bita Javan, Ayesheh Enayati, Morteza Olad nabi, Mehdi Zahedi and Gokhan Zengin
    Citation: BMC Complementary Medicine and Therapies 2023 23:272
    Content type: Research Published on:

  26. Since cancer is one of the most prevalent diseases in the world, further studies are needed to identify the effective therapeutic modalities. The second deadliest and third most common cancer is colorectal can...

    Authors: Nadia S. Mahrous and Enas A. Noseer
    Citation: BMC Complementary Medicine and Therapies 2023 23:271
    Content type: Research Published on:

  27. liver cancer is one of the most common cancers in the world. So far, there is no gold standard treatment for hepatocellular carcinoma. We conducted this in vitro study to assess the effect of three natural pro...

    Authors: Sally Elnawasany, Yusuf A. Haggag, Shahinaz M. Shalaby, Nema A. Soliman, Amira A. EL Saadany, Marwa A. A. Ibrahim and Farid Badria
    Citation: BMC Complementary Medicine and Therapies 2023 23:270
    Content type: Research Published on:

  28. An increasing number of studies have documented the effectiveness on various types of face-to-face and online mindfulness-based interventions (MBIs) in reducing anxiety among general population, but there is a...

    Authors: Chuntana Reangsing, Pimkanabhon Trakooltorwong, Kunnara Maneekunwong, Jintana Thepsaw and Sarah Oerther
    Citation: BMC Complementary Medicine and Therapies 2023 23:269
    Content type: Research Published on:

  29. Amnesic mild cognitive impairment (aMCI) is the main subtype of mild cognitive impairment (MCI) and has the highest risk of conversion to Alzheimer’s disease (AD) among all MCI subtypes. Episodic memory impair...

    Authors: Yalan Dai, Rui Xia, Dan Wang, Shuqian Li, Xu Yuan, Xingjie Li, Jun Liu, Mengyang Wang, Yuxing Kuang and Shangjie Chen
    Citation: BMC Complementary Medicine and Therapies 2023 23:268
    Content type: Study protocol Published on:

  30. Mentha arvensis has been utilized in diverse traditional medicines as an antidiabetic, anticarcinogenic, antiallergic, antifungal, and antibacterial agent. In this work, we have explored the phytochemical analyse...

    Authors: Shah Faisal, Muhammad Hamza Tariq, Riaz Ullah, Sania Zafar, Muhammad Rizwan, Nadia bibi, Aishma Khattak, Noora Amir and Abdullah
    Citation: BMC Complementary Medicine and Therapies 2023 23:267
    Content type: Research Published on:

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2024 24:98

  31. Massage is widely used in exercise-induced skeletal muscle damage (EIMD). It has been proven that massage can improve the morphology and function of damaged skeletal muscle in multiple ways. However, whether m...

    Authors: Qingsong Liu, Songlin Jin, Lunyu Li, Liubu Ayi and Haili Ding
    Citation: BMC Complementary Medicine and Therapies 2023 23:266
    Content type: Research Published on:

  32. Hepatic encephalopathy (HE) is a consequence of chronic or acute liver diseases. This study evaluates the combined effect of gallic acid (GA), and metformin (Met) on the liver and brain damage associated with HE.

    Authors: Ehsan Khedre Mohamed and Dawlat Mohamed Hafez
    Citation: BMC Complementary Medicine and Therapies 2023 23:265
    Content type: Research Published on:

  33. Type 2 diabetes mellitus (T2DM), a growing health problem worldwide, is a metabolic disorder characterized by hyperglycemia due to insulin resistance and defective insulin secretion by pancreatic β-cells. The ...

    Authors: Jin-Young Han, Miey Park and Hae-Jeung Lee
    Citation: BMC Complementary Medicine and Therapies 2023 23:264
    Content type: Research Published on:

  34. The purpose of this study was to demonstrate the in vitro anti-nephritis activity of Rostellularia procumbens (L.) Nees (R. procumbens) extract and to make a preliminary investigation of its anti-nephritis mechan...

    Authors: Mengfan Wang, Yi Zhou, Qiuyuan Jian, Zhongzhu Ai and Shanshan Zhou
    Citation: BMC Complementary Medicine and Therapies 2023 23:263
    Content type: Research article Published on:

  35. Metabolic syndrome (MetS) is a serious concern among postmenopausal women which predisposes them to cardiovascular and cognitive disorders. Healthful diet and exercise training have been essential strategies t...

    Authors: Zeinab Bayat, Arsalan Damirchi, Meysam Hasannejad-Bibalan and Parvin Babaei
    Citation: BMC Complementary Medicine and Therapies 2023 23:262
    Content type: Research Published on:

  36. The overuse of antibiotics leads to the emergence of antibiotic-resistant microbes which causes high mortality worldwide. Therefore, the synthesis of new active compounds has multifunctional activities are the...

    Authors: Abdel-Rahman A. Nassar, Hossam M. Atta, Mohamed Ali Abdel-Rahman, Wageih S. El Naghy and Amr Fouda
    Citation: BMC Complementary Medicine and Therapies 2023 23:261
    Content type: Research Published on:

  37. Garlic (Allium sativum), the underground bulb of the Allium genus, has been consumed on Earth for thousands of years. Many clinical trials of garlic supplementation on components of metabolic syndrome (MetS) have...

    Authors: Zhenyue Fu, Jiayu Lv, Xiya Gao, Haoran Zheng, Shuqing Shi, Xia Xu, Bingxuan Zhang, Huaqin Wu and Qingqiao Song
    Citation: BMC Complementary Medicine and Therapies 2023 23:260
    Content type: Research Published on:

  38. Human adenovirus type-7 (HAdV-7) is a common pathogen that may cause significant morbidity as well as severe complications. Currently, there is no approved drug for the treatment of HAdV-7 infections and the c...

    Authors: Rahma SR. Mahrous, Hoda Fathy and Reham S. Ibrahim
    Citation: BMC Complementary Medicine and Therapies 2023 23:259
    Content type: Research Published on:

  39. Posttraumatic stress disorder (PTSD) can occur after trauma. While PTSD management strategies include first-line pharmacotherapy and psychotherapy, mind–body therapies, such as yoga, are applied in the PTSD po...

    Authors: Nina Laplaud, Anaïck Perrochon, Matthieu Gallou-Guyot, Maarten Moens, Lisa Goudman, Romain David, Philippe Rigoard and Maxime Billot
    Citation: BMC Complementary Medicine and Therapies 2023 23:258
    Content type: Research Published on:

  40. Milk thistle is one of the most popular hepatoprotectants, and is often sold in combination with other ingredients. Botanical supplements are known to be vulnerable to contamination and adulteration, and emerg...

    Authors: Ancuța Cristina Raclariu-Manolică, Quentin Mauvisseau, Renato Paranaiba, Hugo J. De Boer and Carmen Socaciu
    Citation: BMC Complementary Medicine and Therapies 2023 23:257
    Content type: Research Published on:

  41. Knee osteoarthritis (KOA) is a common public health problem and a leading cause of long-term pain, decreased muscle strength, and even disability. Tai Chi has been proved effective and highly recommended for K...

    Authors: Hongyu Yue, Yang Li, Jianwen Ma, Chaoqun Xie, Fangfang Xie, Junhao Cai, Min Fang and Fei Yao
    Citation: BMC Complementary Medicine and Therapies 2023 23:256
    Content type: Study Protocol Published on:

  42. The morbidity of influenza in children increased rapidly in decade. Reduning injection (RDN), a small but fine Chinese herbal formula, has antipyretic, antiviral, anti-inflammatory effects. We intend to evalua...

    Authors: Shuo Yang, Yan-ming Xie and Lian-xin Wang
    Citation: BMC Complementary Medicine and Therapies 2023 23:255
    Content type: Study Protocol Published on:

  43. Carum carvi (caraway) of the Apiaceae family has been used in many cultures as a cooking spice and part of the folk medicine. Previous reports primarily focus on the medicinal properties of caraway seed essential...

    Authors: Taibah Aldakhil, Saud O. Alshammari, Bushra Siraj, Bishoy El-Aarag, Shamshad Zarina, David Salehi and Aftab Ahmed
    Citation: BMC Complementary Medicine and Therapies 2023 23:254
    Content type: Research Published on:

  44. Post-operative pain of endoscopic submucosal dissection (ESD) is always be overlooked and undertreated by endoscopists. However, the incidence of moderate to severe pain after ESD is as high as 44.9% to 62.8%,...

    Authors: Xin-Lu Chang, Xu-Ming Liu, Li-Xin An, Jian-Yong Zheng and Ke Zhang
    Citation: BMC Complementary Medicine and Therapies 2023 23:253
    Content type: Study Protocol Published on:

  45. Although coronavirus disease 2019 (COVID-19) pandemic is still rage worldwide, there are still very limited treatments for human coronaviruses (HCoVs) infections. Xiaochahu decoction (XCHD), which is one of th...

    Authors: Lvjie Xu, Chuipu Cai, Jiansong Fang, Qihui Wu, Jun Zhao, Zhe Wang, Pengfei Guo, Lishu Zheng and Ailin Liu
    Citation: BMC Complementary Medicine and Therapies 2023 23:252
    Content type: Research Published on:

  47. Authors: Seyede Pegah Hamidi, Omid Koohi-Hosseinabadi, Sepideh Khaksar, Ali Ghanbariasad, Amir Reza Dehghanian, Azizallah Dehghan, Zahra Haddadi, Roxana Gorgin, Mojtaba Farjam and Hiva Alipanah
    Citation: BMC Complementary Medicine and Therapies 2023 23:250
    Content type: Correction Published on:

    The original article was published in BMC Complementary Medicine and Therapies 2023 23:225

  48. Ibuprofen is a member of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAIDs) with anti-inflammatory, analgesic, and antipyretic activities used to relieve a variety of pains. The objectiv...

    Authors: Thaddeus H. Gugu, Geraldine C. Agu, Emmanuel M. Uronnachi and Salome A. Chime
    Citation: BMC Complementary Medicine and Therapies 2023 23:249
    Content type: Research Published on:

  49. Misoprostol is the choice drug for inducing an abortion with intrauterine fetal death, but it has several side effects that increase with accumulating the dose received. Induction abortion with cheap and non-i...

    Authors: Hadis Hashemi, Seyedeh Batool Hasanpoor-Azghady, Masoumeh Farahani and Leila Amiri-Farahani
    Citation: BMC Complementary Medicine and Therapies 2023 23:248
    Content type: Research Published on:

  50. Colorectal cancer (CRC) is the third most common type of cancer worldwide. Red beetroot (Beta vulgaris) contains Betanin as its major betacyanin, possessing wide proapoptotic effects. This study aimed to investig...

    Authors: Amir Saber, Nasim Abedimanesh, Mohammad-Hossein Somi, Ahmad Yari Khosroushahi and Shima Moradi
    Citation: BMC Complementary Medicine and Therapies 2023 23:246
    Content type: Research Published on:
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