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  1. The purple pitcher plant, Sarracenia purpurea L., is a widely distributed species in North America with a history of use as both a marketed pain therapy and a traditional medicine in many aboriginal communities. ...

    Authors: Cory S Harris, Muhammad Asim, Ammar Saleem, Pierre S Haddad, John T Arnason and Steffany AL Bennett
    Citation: BMC Complementary and Alternative Medicine 2012 12:245
  2. Gleditsia sinensis thorns have been widely used in traditional Korean medicine for the treatment of several diseases, including obesity, thrombosis, and tumor-related diseases. The aim of the study is to determi...

    Authors: Jin-Mu Yi, Jong-Shik Park, Se-Mi Oh, Jun Lee, Jinhee Kim, Dal-Seok Oh, Ok-Sun Bang and No Soo Kim
    Citation: BMC Complementary and Alternative Medicine 2012 12:243
  3. Couroupita guianensis Aubl. (Lecythidaceae) is commonly called Ayahuma and the Cannonball tree. It is distributed in the tropical regions of northern South America and Southern Caribbean. It has several medicina...

    Authors: Naif Abdullah Al-Dhabi, Chandrasekar Balachandran, Michael Karunai Raj, Veeramuthu Duraipandiyan, Chinnasamy Muthukumar, Savarimuthu Ignacimuthu, Inshad Ali Khan and Vikrant Singh Rajput
    Citation: BMC Complementary and Alternative Medicine 2012 12:242
  4. Evidence is building steadily on the effectiveness of acupuncture therapy in pain relief and repeated acupuncture-induced pain relief is accompanied by improvement of hippocampal neural synaptic plasticity. To...

    Authors: Yong-Hui Gao, Shu-Ping Chen, Jun-Ying Wang, Li-Na Qiao, Fan-Ying Meng, Qiu-Ling Xu and Jun-Ling Liu
    Citation: BMC Complementary and Alternative Medicine 2012 12:241
  5. Although many researchers agree that applying conventional drug-trial quality criteria to CAM studies lacks plausibility, few take on the burden of devising alternative criteria in a specific area of CAM. This...

    Authors: Mikel Aickin
    Citation: BMC Complementary and Alternative Medicine 2012 12:240
  6. Bear bile and Coptidis Rhizoma have been used in Chinese medicine with a long tradition in treating heat-diseases. Both bear bile and Coptidis Rhizoma are used to treat liver diseases in clinical practice of C...

    Authors: Ning Wang, Yibin Feng, Fan Cheung, Oi-Yee Chow, Xuanbin Wang, Weiwei Su and Yao Tong
    Citation: BMC Complementary and Alternative Medicine 2012 12:239
  7. Drug resistance in bacteria has become a global concern and the search for new antibacterial agents is urgent and ongoing. Endophytes provide an abundant reservoir of bioactive metabolites for medicinal exploi...

    Authors: Hanqiao Liang, Yongmei Xing, Juan Chen, Dawei Zhang, Shunxing Guo and Chunlan Wang
    Citation: BMC Complementary and Alternative Medicine 2012 12:238
  8. Cinnamon bark is one of the most popular herbal ingredients in traditional oriental medicine and possesses diverse pharmacological activities including anti-bacterial, anti-viral, and anti-cancer properties. T...

    Authors: Joung-Woo Hong, Ga-Eun Yang, Yoon Bum Kim, Seok Hyun Eom, Jae-Hwan Lew and Hee Kang
    Citation: BMC Complementary and Alternative Medicine 2012 12:237
  9. Traditional plant treatment for diabetes has shown a surging interest in the last few decades. Therefore, the purpose of this study was to assess the hypoglycemic effect of the aqueous extract of C. papaya leaves...

    Authors: Isela Esther Juárez-Rojop, Juan C Díaz-Zagoya, Jorge L Ble-Castillo, Pedro H Miranda-Osorio, Andrés E Castell-Rodríguez, Carlos A Tovilla-Zárate, Arturo Rodríguez-Hernández, Hidemi Aguilar-Mariscal, Teresa Ramón-Frías and Deysi Y Bermúdez-Ocaña
    Citation: BMC Complementary and Alternative Medicine 2012 12:236
  10. Tinnitus, the perception of sound in absence of an external acoustic source, impairs the quality of life in 2% of the population. Since in most cases causal treatment is not possible, the majority of therapeut...

    Authors: Peter M Kreuzer, Monika Goetz, Maria Holl, Martin Schecklmann, Michael Landgrebe, Susanne Staudinger and Berthold Langguth
    Citation: BMC Complementary and Alternative Medicine 2012 12:235
  11. Some researchers think that patients with higher expectations for CAM therapies experience better outcomes and that enthusiastic providers can enhance treatment outcomes. This is in contrast to evidence sugges...

    Authors: Lisa M Schafer, Clarissa Hsu, Emery Rose Eaves, Cheryl Ritenbaugh, Judith Turner, Daniel C Cherkin, Colette Sims and Karen J Sherman
    Citation: BMC Complementary and Alternative Medicine 2012 12:234
  12. Shivering during regional anesthesia is a common complication and is related to a decrease in the patient’s core body temperature. Previous studies have shown that acupuncture on specific acupoints can preserv...

    Authors: Bo-Yan Yeh, Yi-Chun Hsu, Jyun-Yan Huang, I-Ting Shih, Wei-Jia Zhuo, Yung-Fong Tsai, Chee-Jen Chang and Huang-Ping Yu
    Citation: BMC Complementary and Alternative Medicine 2012 12:233
  13. There is wide spread interest in drugs derived from plants as green medicine is believed to be safe and dependable, compared with costly synthetic drugs that have adverse effects.

    Authors: Md Fakruddin, Khanjada Shahnewaj Bin Mannan, Reaz Mohammad Mazumdar and Hafsa Afroz
    Citation: BMC Complementary and Alternative Medicine 2012 12:232
  14. Plant derived compounds have been shown to be important sources of several anti-cancer agents. As cell cycle deregulation and tumor growth are intimately linked, the discovery of new substances targeting event...

    Authors: Monica Farah Pereira, Thiago Martino, Sergio Ranto Dalmau, Márcia Cristina Paes, Christina Barja-Fidalgo, Rodolpho Mattos Albano, Marsen Garcia Pinto Coelho and Kátia Costa de Carvalho Sabino
    Citation: BMC Complementary and Alternative Medicine 2012 12:231
  15. Centipede grass (CG) originates from China and South America and is reported to contain several C-glycosyl flavones and phenolic constituents, including maysin and luteolin derivatives. This study aimed to inv...

    Authors: Hyoung Joon Park, Byung Yeoup Chung, Min-Kwon Lee, Yuno Song, Seung Sik Lee, Gyo Moon Chu, Suk-Nam Kang, Young Min Song, Gon-Sup Kim and Jae-Hyeon Cho
    Citation: BMC Complementary and Alternative Medicine 2012 12:230
  16. The increase in atmospheric CO2 concentration caused by climate change and agricultural practices is likely to affect biota by producing changes in plant growth, allocation and chemical composition. This study wa...

    Authors: Ali Ghasemzadeh, Hawa ZE Jaafar, Ehsan Karimi and Mohd Hafiz Ibrahim
    Citation: BMC Complementary and Alternative Medicine 2012 12:229
  17. Dioscorea bulbifera is an African medicinal plant used to treat microbial infections. In the present study, the methanol extract, fractions (DBB1 and DBB2) and six compounds isolated from the bulbils of D. bulbi...

    Authors: Victor Kuete, Rémy BetrandTeponno, Armelle Tsafack Mbaveng, Léon Azefack Tapondjou, Jacobus J Marion Meyer, Luciano Barboni and Namrita Lall
    Citation: BMC Complementary and Alternative Medicine 2012 12:228
  18. This study was undertaken to evaluate the beneficial effects of a modified prescription of Sutaehwan named Sutaehwan-Gami (SG), created by adding Rhizoma dioscoreae and Carthami semen to Sutaehwan, on menopausal ...

    Authors: Dong-Il Kim, Min Sun Choi, Sok Cheon Pak, Seung-bok Lee and Songhee Jeon
    Citation: BMC Complementary and Alternative Medicine 2012 12:227
  19. Lonicera japonica Thunb. (Caprifoliaceae), a widely used traditional Chinese medicinal plant, is used to treat some infectious diseases and it may have uses as a healthy food and applications in cosmetics and as...

    Authors: Wei-Cheng Chen, Shorong-Shii Liou, Thing-Fong Tzeng, Shiow-Ling Lee and I-Min Liu
    Citation: BMC Complementary and Alternative Medicine 2012 12:226
  20. Orexin A (OXA, hypocretin/hcrt 1) is a newly discovered potential analgesic substance. However, whether OXA is involved in acupuncture analgesia remains unknown. The present study was designed to investigate t...

    Authors: Xiao-Ming Feng, Wen-Li Mi, Fang Xia, Qi-Liang Mao-Ying, Jian-Wei Jiang, Sheng Xiao, Zhi-Fu Wang, Yan-Qing Wang and Gen-Cheng Wu
    Citation: BMC Complementary and Alternative Medicine 2012 12:225
  21. This study evaluated the effects of C. verbenacea essential oil topically administered in a rat periodontitis model.

    Authors: Suzana Peres Pimentel, Guilherme Emerson Barrella, Renato Corrêa Viana Casarin, Fabiano Ribeiro Cirano, Márcio Zaffalon Casati, Mary Ann Foglio, Glyn Mara Figueira and Fernanda Vieira Ribeiro
    Citation: BMC Complementary and Alternative Medicine 2012 12:224
  22. Compound Valeriana jatamansi Jones is a formula for treating anxiety-related diseases in the clinic, which is composed of Valeriana jatamansi Rhizoma et Radix, Ziziphi Spinosae Semen, Albiziae Cortex and Junci Me...

    Authors: Jie-Shu You, Min Peng, Jin-Li Shi, Hu-Zhan Zheng, Yong Liu, Bao-Sheng Zhao and Jian-You Guo
    Citation: BMC Complementary and Alternative Medicine 2012 12:223
  23. Kampo medicines are traditional Japanese medicines produced from medicinal plants and herbs. Even though the efficacy of Kampo medicines for controlling cancer-related symptoms is being reported, their actual ...

    Authors: Satoru Iwase, Takuhiro Yamaguchi, Tempei Miyaji, Kiyoshi Terawaki, Akio Inui and Yasuhito Uezono
    Citation: BMC Complementary and Alternative Medicine 2012 12:222
  24. The aim of this study was to screen various solvent extracts of whole plant of Torilis leptophylla to display potent antioxidant activity in vitro and in vivo, total phenolic and flavonoid contents in order to fi...

    Authors: Naima Saeed, Muhammad R Khan and Maria Shabbir
    Citation: BMC Complementary and Alternative Medicine 2012 12:221
  25. Breast cancer is the most common form of cancer and the focus on finding chemotherapeutic agents have recently shifted to natural products. Piper betle is a medicinal plant with various biological activities. How...

    Authors: Noor Nazirahanie Abrahim, M S Kanthimathi and Azlina Abdul-Aziz
    Citation: BMC Complementary and Alternative Medicine 2012 12:220
  26. Integrative medicine (IM) is currently the most commonly used term to describe the integration of complementary and alternative medicine (CAM) into conventional medicine. In the definitions of IM the most impo...

    Authors: Christine Holmberg, Benno Brinkhaus and Claudia Witt
    Citation: BMC Complementary and Alternative Medicine 2012 12:218
  27. Traditional folk medicinal plants have recently become popular and are widely used for primary health care. Since Thailand has a great diversity of indigenous (medicinal) plant species, this research investiga...

    Authors: Chutima Kaewpiboon, Kriengsak Lirdprapamongkol, Chantragan Srisomsap, Pakorn Winayanuwattikun, Tikamporn Yongvanich, Preecha Puwaprisirisan, Jisnuson Svasti and Wanchai Assavalapsakul
    Citation: BMC Complementary and Alternative Medicine 2012 12:217
  28. Stroke is one of the leading causes of death and disability in China. Current treatments for stroke are limited and achieve no optimal effect. Acupuncture is widely used in the treatment of stroke and in impro...

    Authors: Huilin Liu, Dangsheng Zhang, Xiuge Tan, Daqing Yang, Guiling Wang, Yin Zhao, Yali Wen, Guangxia Shi and Linpeng Wang
    Citation: BMC Complementary and Alternative Medicine 2012 12:216
  29. Carpobrotus edulis (Mesembryanthemaceae), also known as igcukuma in Xhosa language is a medicinal plant used by the traditional healers to treat common infections in HIV/AIDS patients. Based on this information,...

    Authors: Beauty E Omoruyi, Graeme Bradley and Anthony J Afolayan
    Citation: BMC Complementary and Alternative Medicine 2012 12:215
  30. Dengue is a serious arboviral disease currently with no effective antiviral therapy or approved vaccine available. Therefore, finding the effective compound against dengue virus (DENV) replication is very impo...

    Authors: Keivan Zandi, Boon-Teong Teoh, Sing-Sin Sam, Pooi-Fong Wong, Mohd Rais Mustafa and Sazaly AbuBakar
    Citation: BMC Complementary and Alternative Medicine 2012 12:214
  31. Diseases caused by microorganisms and parasites remain a major challenge globally and particularly in sub-Saharan Africa to man and livestock. Resistance to available antimicrobials and the high cost or unavai...

    Authors: Mathew Adamu, Vinasan Naidoo and Jacobus N Eloff
    Citation: BMC Complementary and Alternative Medicine 2012 12:213
  32. Irritable bowel syndrome is a chronic condition with no known cure. Many sufferers seek complementary and alternative medicine including homeopathic treatment. However there is much controversy as to the effec...

    Authors: Emily J Peckham, Clare Relton, Jackie Raw, Clare Walters, Kate Thomas and Christine Smith
    Citation: BMC Complementary and Alternative Medicine 2012 12:212
  33. The use of complementary and alternative medicine (CAM) continues to increase in Taiwan. This study examined the use of CAM and beliefs about CAM as expressed by patients with traumatic brain injury (TBI) in T...

    Authors: Bih-Shya Gau, Hsiao-Ling Yang, Sheng-Jean Huang and Meei-Fang Lou
    Citation: BMC Complementary and Alternative Medicine 2012 12:211
  34. Angiogenesis plays a critical role in embryonic development and various physiological processes. However, excessive angiogenesis is associated with several pathological conditions including cancer. Pithecellobium...

    Authors: Nahdzatul Syima Muslim, Zeyad D Nassar, Abdalrahim FA Aisha, Armaghan Shafaei, Norshirin Idris, AminMalikShahAbdul Majid and Zhari Ismail
    Citation: BMC Complementary and Alternative Medicine 2012 12:210
  35. Multiple sclerosis (MS) is a complex autoimmune disease mediated by an immune response to central nervous system antigens. Modern immunomodulatory therapies, however, do not ameliorate many of the symptoms, su...

    Authors: Juan G Quispe-Cabanillas, Alfredo Damasceno, Felipe von Glehn, Carlos O Brandão, Benito P Damasceno, Wanderley D Silveira and Leonilda MB Santos
    Citation: BMC Complementary and Alternative Medicine 2012 12:209
  36. The anticancer and immunomodulatory activity of mung bean sprouts (MBS) and the underlying mechanisms against human cervical and hepatocarcinoma cancer cells were explored.

    Authors: Rand R Hafidh, Ahmed S Abdulamir, Fatimah Abu Bakar, Farid Azizi Jalilian, Faridah Abas and Zamberi Sekawi
    Citation: BMC Complementary and Alternative Medicine 2012 12:208
  37. There have been a few but not precise surveys of the current status of traditional Japanese Kampo education at medical schools in Japan. Our aim was to identify problems and suggest solutions for a standardize...

    Authors: Makoto Arai, Shuichi Katai, Shin-ichi Muramatsu, Takao Namiki, Toshihiko Hanawa and Shun-ichiro Izumi
    Citation: BMC Complementary and Alternative Medicine 2012 12:207
  38. The dibenzylbutyrolactone lignan (−)-hinokinin (HK) was derived by partial synthesis from (−)-cubebin, isolated from the dry seeds of the pepper, Piper cubeba. Considering the good trypanosomicidal activity of HK...

    Authors: Flávia Aparecida Resende, Lilian Cristina Barbosa, Denise Crispim Tavares, Mariana Santoro de Camargo, Karen Cristina de Souza Rezende, Márcio Luis de Andrade e Silva and Eliana Aparecida Varanda
    Citation: BMC Complementary and Alternative Medicine 2012 12:203
  39. Drugs used both in classical chemotherapy and the more recent targeted therapy do not have cancer cell specificity and, hence, cause severe systemic side effects. Tumors also develop resistance to such drugs d...

    Authors: Nasser M Al-Daghri, Majed S Alokail, Khalid M Alkharfy, Abdul Khader Mohammed, Sherif H Abd-Alrahman, Sobhy M Yakout, Osama E Amer and Soundararajan Krishnaswamy
    Citation: BMC Complementary and Alternative Medicine 2012 12:202
  40. Previous studies have demonstrated that the consumption of green tea inhibits the growth of various cancers. Most cancers are believed to be initiated from and maintained by a small population of cancer stem-l...

    Authors: Chien-Hung Lin, Yao-An Shen, Peir-Haur Hung, Yuan-Bin Yu and Yann-Jang Chen
    Citation: BMC Complementary and Alternative Medicine 2012 12:201
  41. This study evaluated, using in vitro assays, the antibacterial, antioxidant, and tyrosinase-inhibition activities of methanolic extracts from peels of seven commercially grown pomegranate cultivars.

    Authors: Olaniyi A Fawole, Nokwanda P Makunga and Umezuruike Linus Opara
    Citation: BMC Complementary and Alternative Medicine 2012 12:200
  42. In folk medicine, the aerial part of Crytotaenia japonica Hassk. (CJ), is applied for treatment of the common cold, cough, urinary problems, pneumonia, and skin rashes. In this paper, the in vitro and in vivo ant...

    Authors: Hee Kang, Tae-Sun Bang, Ji-Won Lee, Jae-Hwan Lew, Seok Hyun Eom, Kyungjin Lee and Ho-Young Choi
    Citation: BMC Complementary and Alternative Medicine 2012 12:199
  43. Over 30% of individuals use natural health products (NHPs) for osteoarthritis-related pain. The Deficit Model for the Public Understanding of Science suggests that if individuals are given more information (es...

    Authors: Teresa Tsui, Heather Boon, Andreas Boecker, Natasha Kachan and Murray Krahn
    Citation: BMC Complementary and Alternative Medicine 2012 12:198
  44. Traditional Chinese medicine (TCM) has been used to treat chronic obstructive pulmonary disease (COPD) for many years. This study aimed to evaluate the efficacy and safety of the comprehensive therapy based on...

    Authors: Su-yun Li, Jian-sheng Li, Ming-hang Wang, Yang Xie, Xue-qing Yu, Zi-kai Sun, Li-jun Ma, Wei Zhang, Hai-long Zhang, Fan Cao and Ying-chao Pan
    Citation: BMC Complementary and Alternative Medicine 2012 12:197
  45. Microglial activation plays an important role in neurodegenerative diseases by producing several pro-inflammatory enzymes and pro-inflammatory cytokines. Lipopolysaccharide (LPS)-induced inflammation leads to ...

    Authors: Kang-Woo Lee, So Young Jung, Sun-Mi Choi and Eun Jin Yang
    Citation: BMC Complementary and Alternative Medicine 2012 12:196
  46. Many cancers contain cell subpopulations that display characteristics of stem cells. Because these cancer stem cells (CSCs) appear to provide resistance to chemo-radiation therapy, development of therapeutic a...

    Authors: Taghreed N Almanaa, Michael E Geusz and Roudabeh J Jamasbi
    Citation: BMC Complementary and Alternative Medicine 2012 12:195