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  1. High-cholesterol diet (HCD) increases the oxidative stress in different tissues leading to many diseases. Rutin (RT) is a natural flavonoid (vitamin p), which possesses an antioxidant activity with protective ...

    Authors: Salem S Al-Rejaie, Abdulaziz M Aleisa, Mohamed M Sayed-Ahmed, Othman A AL-Shabanah, Hatem M Abuohashish, Mohammed M Ahmed, Khaled A Al-Hosaini and Mohamed M Hafez
    Citation: BMC Complementary and Alternative Medicine 2013 13:136
  2. We have previously reported that aerial parts of Tylophora hirsuta have antispasmodic profile. The current work is an attempt for isolation of pharmacologically active compound(s) that contribute for its antispas...

    Authors: Niaz Ali
    Citation: BMC Complementary and Alternative Medicine 2013 13:135
  3. Transcutaneous electrical nerve stimulation (TENS) is a non-pharmacologic treatment for pain relief. In previous animal studies, TENS effectively alleviated Complete Freund’s Adjuvant (CFA)- or carrageenan-ind...

    Authors: Jun-Fan Fang, Yi Liang, Jun-Ying Du and Jian-Qiao Fang
    Citation: BMC Complementary and Alternative Medicine 2013 13:134
  4. The plant genus Fallopia is well-known in Chinese traditional medicine and includes many species that contain bioactive compounds, namely phytoestrogens. Consumption of phytoestrogens may be linked to decreased i...

    Authors: Jennifer C Brennan, Michael S Denison, Dirk M Holstege, Prokopios Magiatis, Jerry L Dallas, Elisa G Gutierrez, Anatoly A Soshilov and James R Millam
    Citation: BMC Complementary and Alternative Medicine 2013 13:133
  5. Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China. Due to its worldwide use, potential impact on healthcare and opportunities for new drug development, TCM is also of great...

    Authors: Qihe Xu, Rudolf Bauer, Bruce M Hendry, Tai-Ping Fan, Zhongzhen Zhao, Pierre Duez, Monique SJ Simmonds, Claudia M Witt, Aiping Lu, Nicola Robinson, De-an Guo and Peter J Hylands
    Citation: BMC Complementary and Alternative Medicine 2013 13:132
  6. Women with polycystic ovary syndrome (PCOS) have symptoms of depression and anxiety and impaired health related quality of life (HRQoL). Here we test the post-hoc hypothesis that acupuncture and exercise impro...

    Authors: Elisabet Stener-Victorin, Göran Holm, Per Olof Janson, Deborah Gustafson and Margda Waern
    Citation: BMC Complementary and Alternative Medicine 2013 13:131
  7. Antibacterial activity of honey is mainly dependent on a combination of its peroxide activity and non-peroxide components. This study aims to investigate antibacterial activity of five varieties of Malaysian h...

    Authors: Mohd Izwan Zainol, Kamaruddin Mohd Yusoff and Mohd Yasim Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2013 13:129
  8. Colorectal cancer remains one of the leading causes of cancer death worldwide. Traditional Chinese Medicine (TCM) has played a positive role in colorectal cancer treatment. There is a great need to establish e...

    Authors: Shan Deng, Bing Hu, Hong-Mei An, Qin Du, Ling Xu, Ke-Ping Shen, Xiu-Feng Shi, Meng-Meng Wei and Yang Wu
    Citation: BMC Complementary and Alternative Medicine 2013 13:128
  9. Based on the reported antioxidant and anti-inflammatory potential of Terminalia paniculata, the bark aqueous extract (TPW) was investigated against liver damage.

    Authors: Sahil Talwar, Hitesh V Jagani, Pawan G Nayak, Nitesh Kumar, Anoop Kishore, Punit Bansal, Rekha R Shenoy and Krishnadas Nandakumar
    Citation: BMC Complementary and Alternative Medicine 2013 13:127
  10. The TRAMIL program aims to understand, validate and expand health practices based on the use of medicinal plants in the Caribbean, which is a “biodiversity hotspot” due to high species endemism, intense develo...

    Authors: Claribel Luciano-Montalvo, Isabelle Boulogne and Jannette Gavillán-Suárez
    Citation: BMC Complementary and Alternative Medicine 2013 13:126
  11. The aim of this publication is to present a case study of how to locate and appraise qualitative studies for the conduct of a meta-ethnography in the field of complementary and alternative medicine (CAM). CAM ...

    Authors: Brigitte Franzel, Martina Schwiegershausen, Peter Heusser and Bettina Berger
    Citation: BMC Complementary and Alternative Medicine 2013 13:125
  12. Personalised (or individualised) medicine in the days of genetic researchrefers to molecular biologic specifications in individuals and not to aresponse to individual patient needs in the sense of person-centr...

    Authors: Brigitte Franzel, Martina Schwiegershausen, Peter Heusser and Bettina Berger
    Citation: BMC Complementary and Alternative Medicine 2013 13:124
  13. Yi Guan Jian Decoction (YGJD), a famous Chinese prescription, has long been employed clinically to treat liver fibrosis. However, as of date, there is no report on the effects of YGJD from a metabonomic approa...

    Authors: Xiaojun Gou, Qing Tao, Qin Feng, Jinghua Peng, Yu Zhao, Jianye Dai, Wenyu Wang, Yongyu Zhang, Yiyang Hu and Ping Liu
    Citation: BMC Complementary and Alternative Medicine 2013 13:123
  14. Patients’ expectations of osteopathic care have been little researched. The aim of this study was to quantify the most important expectations of patients in private UK osteopathic practices, and the extent to ...

    Authors: CM Janine Leach, Anne Mandy, Matthew Hankins, Laura M Bottomley, Vinette Cross, Carol A Fawkes, Adam Fiske and Ann P Moore
    Citation: BMC Complementary and Alternative Medicine 2013 13:122
  15. Egyptians recognized the healing power of herbs and used them in their medicinal formulations. Nowadays, “Attarin” drug shops and the public use mainly the Unani medicinal system for treatment of their health ...

    Authors: Shereen K Ali, Ahmed R Hamed, Maha M Soltan, Usama M Hegazy, Esameldin E Elgorashi, Ibrahim A El-Garf and Ahmed A Hussein
    Citation: BMC Complementary and Alternative Medicine 2013 13:121
  16. Parthenium hysterophorus L. (Asteraceae) is a common weed occurring throughout the globe. In traditional medicine its decoction has been used for treatment of many infectious and degenerative diseases. This work...

    Authors: Shashank Kumar, Amita Mishra and Abhay K Pandey
    Citation: BMC Complementary and Alternative Medicine 2013 13:120
  17. A traditional Chinese Medicine (TCM) formula, HZJW, has been applied in clinics in China for gastrointestinal disorders. However, the therapeutic mechanism underlying its efficacy and safety remained to be def...

    Authors: Jian-Hui Xie, Yun-Long Chen, Qing-He Wu, Jun Wu, Ji-Yan Su, Hong-Yin Cao, Yu-Cui Li, Yi-Sheng Li, Jin-Bin Liao, Xiao-Ping Lai, Ping Huang and Zi-Ren Su
    Citation: BMC Complementary and Alternative Medicine 2013 13:119
  18. Diabetes is a serious metabolic disorder affecting the metabolism of carbohydrate, protein and fat. A number of studies have shown that diabetes mellitus is associated with oxidative stress, leading to an incr...

    Authors: Hasni Misbah, Azlina Abdul Aziz and Norhaniza Aminudin
    Citation: BMC Complementary and Alternative Medicine 2013 13:118
  19. Dental caries is an infectious disease which results from the acidic demineralisation of the tooth enamel and dentine as a consequence of the dental plaque (a microbial biofilm) accumulation. Research showed t...

    Authors: Caterina Signoretto, Anna Marchi, Anna Bertoncelli, Gloria Burlacchini, Alberto Milli, Francesco Tessarolo, Iole Caola, Adele Papetti, Carla Pruzzo, Egija Zaura, Peter Lingström, Itzhak Ofek, David A Spratt, Jonathan Pratten, Michael Wilson and Pietro Canepari
    Citation: BMC Complementary and Alternative Medicine 2013 13:117
  20. Oxidative stress has been implicated in the progression of various diseases, which may result in the depletion of endogenous antioxidants. Exogenous supplementation with antioxidants could result in increased ...

    Authors: Werner Cordier, Mary Gulumian, Allan Duncan Cromarty and Vanessa Steenkamp
    Citation: BMC Complementary and Alternative Medicine 2013 13:116
  21. Chromatin, residing in the nuclei of eukaryotic cells, comprises DNA and histones to make up chromosomes. Chromatin condenses to compact the chromosomes and loosens to facilitate gene transcription and DNA rep...

    Authors: Hsin-Ying Hsieh, Pei-Hsun Chiu and Sun-Chong Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:115
  22. Reflexology is an alternative medical practice that produces beneficial effects by applying pressure to specific reflex areas. Our previous study suggested that reflexological stimulation induced cortical acti...

    Authors: Naoki Miura, Yuko Akitsuki, Atsushi Sekiguchi and Ryuta Kawashima
    Citation: BMC Complementary and Alternative Medicine 2013 13:114
  23. Distressed individuals in Korea may benefit from the practice of mind–body exercises such as Qigong. However, the effectiveness of such techniques needs to be investigated.

    Authors: Eun-Young Hwang, Sun-Yong Chung, Jae-Heung Cho, Mi-Yeon Song, Sehyun Kim and Jong-Woo Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:113
  24. Osteoclasts are primarily responsible for bone resorption. In many pathological bone diseases including osteoporosis and rheumatoid arthritis, osteoclasts are excessively activated. Thus, controlling of osteoc...

    Authors: Hyunil Ha, Ki-Shuk Shim, Hyosun An, Taesoo Kim and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:112
  25. Plants of the genus Maytenus belong to the family Celastraceae and are widely used in folk medicine as anti-tumour, anti-asthmatic, analgesic, anti-inflammatory, antimicrobial and anti-ulcer agents, and as a trea...

    Authors: Tsholofelo Abednego Mokoka, Lyndy Joy McGaw, Ladislaus Kakore Mdee, Victor Patrick Bagla, Ezekiel Olugbenga Iwalewa and Jacobus Nicolaas Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:111
  26. Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.

    Authors: Adelina Jiménez-Arellanes, Julieta Luna-Herrera, Ricardo Ruiz-Nicolás, Jorge Cornejo-Garrido, Amparo Tapia and Lilián Yépez-Mulia
    Citation: BMC Complementary and Alternative Medicine 2013 13:109
  27. Traditional Japanese Medicine (Kampo) is often used in Japan, but very little data on its users are available. We investigated who uses Kampo, the reasons and opinions for its use.

    Authors: Lydia Hottenbacher, Thorolf ER Weißhuhn, Kenji Watanabe, Takashi Seki, Julia Ostermann and Claudia M Witt
    Citation: BMC Complementary and Alternative Medicine 2013 13:108
  28. Teas from the husk fiber of Cocos nucifera are used in the folk medicine to treat arthritis and other inflammatory processes. Some works show that some varieties have biological activities. However, one of the ma...

    Authors: Rafaela Ribeiro Silva, Davi Oliveira e Silva, Humberto Rollemberg Fontes, Celuta Sales Alviano, Patricia Dias Fernandes and Daniela Sales Alviano
    Citation: BMC Complementary and Alternative Medicine 2013 13:107
  29. Hwangryun-haedok-tang (HRT) is traditional herbal medicine used to treat inflammatory-related diseases in Asia. However, its effect on osteoclastogenesis and bone loss is still unknown. In this study, we evalu...

    Authors: Ki-Shuk Shim, Taesoo Kim, Hyunil Ha, Kwang Jin Lee, Chang-Won Cho, Han Sung Kim, Dong-Hyun Seo and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:106
  30. Radiation-induced skin injury is a common complication of radiotherapy. The RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract (RCE) can ameliorate radiation-induced skin injury in our clinical observation. Bu...

    Authors: Xi-Jing Wang, Shuai Lin, Hua-Feng Kang, Zhi-Jun Dai, Ming-Hua Bai, Xiu-Long Ma, Xiao-Bin Ma, Meng-jie Liu, Xiao-Xu Liu and Bao-Feng Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:105
  31. Diabetes remains a major health problem worldwide. Low-risk low-cost alternatives to pharmaceutical interventions are needed where lifestyle modifications have failed. We conducted a double-blind randomised pl...

    Authors: Suzanne J Grant, Dennis Hsu-Tung Chang, Jianxun Liu, Vincent Wong, Hosen Kiat and Alan Bensoussan
    Citation: BMC Complementary and Alternative Medicine 2013 13:104
  32. Radiation therapy is the most widely used treatment for cancer, but it causes the side effect of mucositis due to intestinal damage. We examined the protective effect of genistein in tumor-bearing mice after a...

    Authors: Tae Gen Son, Eun Ji Gong, Min Ji Bae, Sung Dae Kim, Kyu Heo, Changjong Moon, Kwangmo Yang and Joong Sun Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:103
  33. Like any other form of healthcare, acupuncture takes place in a particular context which can enhance or diminish treatment outcomes (i.e. can produce contextual effects). Patients’ expectations of acupuncture ...

    Authors: Felicity L Bishop and George T Lewith
    Citation: BMC Complementary and Alternative Medicine 2013 13:102
  34. Caesalpinia bonducella is an important medicinal plant for its traditional uses against different types of diseases. Therefore, the present study investigated the antimicrobial, antidiarrhoeal, and cytotoxic act...

    Authors: Muhammad Mutassim Billah, Rafikul Islam, Hajera Khatun, Shahnaj Parvin, Ekramul Islam, SM Anisul Islam and Akbar Ali Mia
    Citation: BMC Complementary and Alternative Medicine 2013 13:101
  35. Microbial infections and resulting inflammation and oxidative stress are common pathogenesis of gastrointestinal tract (GIT) disorders. In South Africa, several species of the genus Maytenus are used in tradition...

    Authors: Aroke Shahid Ahmed, Lyndy J McGaw and Jacobus N Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:100
  36. The aims of this study were to evaluate the antioxidant activity and to identify the antioxidant components of a traditional Chinese medicine formula consisting of a combination of Shanzha (the fruit of Crataegus...

    Authors: Cheng-Yu Chen, Hua Li, Ya-Nan Yuan, Hui-Qing Dai and Bin Yang
    Citation: BMC Complementary and Alternative Medicine 2013 13:99
  37. Anemia is a condition that has multiple origins. One such origin is the destruction of red blood cells’ (RBCs) membrane induced by free radicals. Treatment of anemia could therefore be enhanced by the use of f...

    Authors: Prosper Cabral Nya Biapa, Horea Matei, Ştefana Bâlici, Julius Eyong Oben and Jeanne Yonkeu Ngogang
    Citation: BMC Complementary and Alternative Medicine 2013 13:98
  38. St. John’s wort (Hypericum perforatum L.) is an herbaceous plant that is native to Europe, West Asia and North Africa and that is recognized and used worldwide for the treatment of mild and moderate depression. I...

    Authors: Ana Paula Peron, Rosinete Gonçalves Mariucci, Igor Vivian de Almeida, Elisângela Düsman, Mário Sérgio Mantovani and Veronica Elisa Pimenta Vicentini
    Citation: BMC Complementary and Alternative Medicine 2013 13:97
  39. The current work is an attempt to know about additional chemical profile of Artemisia macrocephala. Antioxidant activity is performed as the plant is reported to contain flavonoids, which have antioxidant activit...

    Authors: Niaz Ali, Ismail Shah, Syed Wadood Ali Shah, Ghayour Ahmed, Mohammad Shoaib, Muhammad Junaid, Waqar Ali and Zahoor Ahmed
    Citation: BMC Complementary and Alternative Medicine 2013 13:96
  40. During the last decades, the number of people suffering from dermatophytoses has seriously increased, mainly due to the development of resistant strains of microorganisms to a range of formally efficient antib...

    Authors: Guy Sedar Singor Njateng, Donatien Gatsing, Raymond Simplice Mouokeu, Paul Keilah Lunga and Jules-Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2013 13:95
  41. Some Ficus species have been used in traditional African medicine in the treatment of diabetes. The antidiabetic potential of certain species has been confirmed in vivo but the mechanism of activity remains uncer...

    Authors: Oyinlola O Olaokun, Lyndy J McGaw, Jacobus N Eloff and Vinny Naidoo
    Citation: BMC Complementary and Alternative Medicine 2013 13:94
  42. Ginkgo biloba extract (GbE) is used extensively by breast cancer patients undergoing treatment with Tamoxifen (TAM). Thus, the present study investigated the effects of GbE in female Sprague–Dawley (SD) rats bea...

    Authors: Marcos Correa Dias, Kelly Silva Furtado, Maria Aparecida Marchesan Rodrigues and Luís Fernando Barbisan
    Citation: BMC Complementary and Alternative Medicine 2013 13:93
  43. Prunus yedoensis (PY) is a traditional anti-allergy and anti-inflammatory herb medicine used in South Korea. However, until date, little is known regarding its mechanism of action.

    Authors: Juyeong Lee, Gabsik Yang, Kyungjin Lee, Mi-Hwa Lee, Ji-Whan Eom, Inhye Ham and Ho-Young Choi
    Citation: BMC Complementary and Alternative Medicine 2013 13:92
  44. Scutellaria baicalensis (S. baicalensis) is one of the traditional Chinese medicinal herbs that have been shown to possess many health benefits. In the present study, we evaluated the in vitro antiviral activity...

    Authors: Keivan Zandi, Tong-Hye Lim, Nor-Aziyah Rahim, Meng-Hooi Shu, Boon-Teong Teoh, Sing-Sin Sam, Mohammed-Bashar Danlami, Kim-Kee Tan and Sazaly Abubakar
    Citation: BMC Complementary and Alternative Medicine 2013 13:91
  45. Cranberry fruits possess many biological activities partly due to their various phenolic compounds; however the underlying modes of action are poorly understood. We studied the effect of cranberry fruit extrac...

    Authors: Moussa S Diarra, Glenn Block, Heidi Rempel, B Dave Oomah, Judy Harrison, Jason McCallum, Simon Boulanger, Éric Brouillette, Mariza Gattuso and François Malouin
    Citation: BMC Complementary and Alternative Medicine 2013 13:90
  46. Activated hepatic stellate cells (aHSCs) play an important role in the progression of hepatocellular carcinoma (HCC). Here, we determined if cytokines secreted in response to the herbal compound “Songyou Yin” ...

    Authors: Qing-An Jia, Zhi-Ming Wang, Zheng-Gang Ren, Yang Bu, Xiao-Ying Xie, Yan-Hong Wang, Lan Zhang, Qiang-Bo Zhang, Tong-Chun Xue, Li-Fen Deng and Zhao-You Tang
    Citation: BMC Complementary and Alternative Medicine 2013 13:89
  47. Computer-aided drug design (CADD) often involves virtual screening (VS) of large compound datasets and the availability of such is vital for drug discovery protocols. We present CamMedNP - a new database begin...

    Authors: Fidele Ntie-Kang, James A Mbah, Luc Meva’a Mbaze, Lydia L Lifongo, Michael Scharfe, Joelle Ngo Hanna, Fidelis Cho-Ngwa, Pascal Amoa Onguéné, Luc C Owono Owono, Eugene Megnassan, Wolfgang Sippl and Simon MN Efange
    Citation: BMC Complementary and Alternative Medicine 2013 13:88
  48. Tai Chi training enhances physical function and may reduce falls in older adults with and without balance disorders, yet its effect on postural control as quantified by the magnitude or speed of center-of-pres...

    Authors: Brad Manor, Lewis A Lipsitz, Peter M Wayne, C-K Peng and Li Li
    Citation: BMC Complementary and Alternative Medicine 2013 13:87