Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R: Physical basis of cognitive alterations in Alzheimer’s disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol. 1991, 30 (4): 572-580. 10.1002/ana.410300410.
Article
CAS
PubMed
Google Scholar
Roberson MR, Harrell LE: Cholinergic activity and amyloid precursor protein metabolism. Brain Res Brain Res Rev. 1997, 25 (1): 50-69. 10.1016/S0165-0173(97)00016-7.
Article
CAS
PubMed
Google Scholar
Greenblatt HM, Kryger G, Lewis T, Silman I, Sussman JL: Structure of acetylcholinesterase complexed with (−)-galanthamine at 2.3 A resolution. FEBS Lett. 1999, 463 (3): 321-326. 10.1016/S0014-5793(99)01637-3.
Article
CAS
PubMed
Google Scholar
Dolmella A, Bandoli G, Nicolini M: Alzheimer’s disease: a pharmacological challenge. Adv Drug Res. 1994, 25: 203-294.
CAS
Google Scholar
Greenlee W, Clader J, Asberom T, McCombie S, Ford J, Guzik H, Kozlowski J, Li S, Liu C, Lowe D: Muscarinic agonists and antagonists in the treatment of Alzheimer’s disease. Farmaco. 2001, 56 (4): 247-250. 10.1016/S0014-827X(01)01102-8.
Article
CAS
PubMed
Google Scholar
Wesseling H, Agoston S, Van Dam GB, Pasma J, DeWit DJ, Havinga H: Effects of 4-aminopyridine in elderly patients with Alzheimer’s disease. N Engl J Med. 1984, 310 (15): 988-989.
Article
CAS
PubMed
Google Scholar
Villarroya M, Garcia AG, Marco JL: New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer’s disease. Curr Pharm Design. 2004, 10 (25): 3177-3184. 10.2174/1381612043383368.
Article
CAS
Google Scholar
Darreh-Shori T, Soininen H: Effects of cholinesterase inhibitors on the activities and protein levels of cholinesterases in the cerebrospinal fluid of patients with Alzheimer’s disease: a review of recent clinical studies. Curr Alzheimer Res. 2010, 7 (1): 67-73. 10.2174/156720510790274455.
Article
CAS
PubMed
Google Scholar
Lipsky PE: The clinical potential of cyclooxygenase-2-specific inhibitors. Am J Med. 1999, 106 (5B): 51S-57S.
Article
CAS
PubMed
Google Scholar
Mariani E, Polidori MC, Cherubini A, Mecocci P: Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B Analyt Technol Biomed Life Sci. 2005, 827 (1): 65-75. 10.1016/j.jchromb.2005.04.023.
Article
CAS
PubMed
Google Scholar
Al-Antaki D: TadhkiratUla li-'Lbabwa 'l-Jami'al-'Ujab al-'Ujab. 1935, Cairo: Bulaq
Google Scholar
Al-Turkimany JOA: AlMoi'tamad Fil a-'dweah Almofradah (The source of the single Pharmaceuticals). Revised by AlSaka M. 1993, Beirut, Lebanon: Dar AlKalam Publishing
Google Scholar
Avicenna AH: Al-Kanoon Fi Altib (The Rules of Medicine). 1993, Beirut, Lebanon: IzAldin Publications, 1037-
Google Scholar
Ibn AlBitar DAM: AlJame Li-Mofradat al Adwiyah wal Aghthiyah. The collection of Medical and Food Items. 1874, Beirut, Lebanon: Dar Sader Publishing
Google Scholar
Ellman GL, Courtney KD, Andres V, Feather-Stone RM: A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol. 1961, 7: 88-95. 10.1016/0006-2952(61)90145-9.
Article
CAS
PubMed
Google Scholar
Lee JH, Lee KT, Yang JH, Baek NI, Kim DK: Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel. Arch Pharm Res. 2004, 27 (1): 53-56. 10.1007/BF02980046.
Article
CAS
PubMed
Google Scholar
Jager AK, Hutchings A, van Staden J: Screening of Zulu medicinal plants for prostaglandin-synthesis inhibitors. J Ethnopharmacol. 1996, 52 (2): 95-100. 10.1016/0378-8741(96)01395-5.
Article
CAS
PubMed
Google Scholar
Hamed A: Investigation of multiple cytoprotective actions of some individual phytochemicals and plant extracts. 2009, United Kingdom: The University of Nottingham
Google Scholar
Nara K, Miyoshi T, Honma T, Koga H: Antioxidative activity of bound-form phenolics in potato peel. Biosci Biotech Bioch. 2006, 70 (6): 1489-1491. 10.1271/bbb.50552.
Article
CAS
Google Scholar
Bin Murad I: Research into the history of the medicine and pharmacology of the Arabs. 1991, Beirut, Lebanon: Dar AlGarb AlIslami
Google Scholar
Aboelsoud NH: Herbal medicine in ancient Egypt. J Med Plants Res. 2010, 4: 82-86.
Google Scholar
Mehta M, Adem A, Sabbagh M: New acetylcholinesterase inhibitors for Alzheimer’s disease. IJAD. 2012, 2012: 728983-
PubMed
Google Scholar
Gauthier S, Emre M, Farlow MR, Bullock R, Grossberg GT, Potkin SG: Strategies for continued successful treatment of Alzheimer’s disease: switching cholinesterase inhibitors. Curr Med Res Opin. 2003, 19 (8): 707-714. 10.1185/030079903125002450.
Article
PubMed
Google Scholar
Cao R, Peng W, Wang Z, Xu A: beta-Carboline alkaloids: biochemical and pharmacological functions. Curr Med Chem. 2007, 14 (4): 479-500. 10.2174/092986707779940998.
Article
CAS
PubMed
Google Scholar
Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H: β-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). Food Chem Toxicol. 2010, 48 (3): 839-845. 10.1016/j.fct.2009.12.019.
Article
CAS
PubMed
Google Scholar
Sobhani AM, Ebrahimi SA, Mahmoudian M: An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids. J Pharm Pharm Sci. 2002, 5 (1): 19-23.
PubMed
Google Scholar
Bailey ME: Major poisonous plant problems in cattle. Bovine Pract. 1979, 14: 169-175.
Google Scholar
Budavari S, Neil MJO: The Merck Index. 1996, New Jersey: CRC Press, 12
Google Scholar
Muller A, Antus S, Bittinger M, Kaas A, Kreher B, Neszmelyi A, Stuppner H, Wagner H: Chemistry and pharmacology of antiasthmatic Galphimia glauca, Adhatoda vasica, and Picrorhiza kurrooa. Planta Med. 1993, 59 (Suppl. A): 586-587.
Article
Google Scholar
Hoozemans JJ, O’Banion MK: The role of COX-1 and COX-2 in Alzheimer’s disease pathology and the therapeutic potentials of non-steroidal anti-inflammatory drugs. Curr Drug Targets CNS Neurol Disord. 2005, 4 (3): 307-315. 10.2174/1568007054038201.
Article
CAS
PubMed
Google Scholar
Uchida K: Japan Patent Kokai. 2006, -016362.2006
Google Scholar
Vanmierlo T, Popp J, Kölsch H, Friedrichs S, Jessen F, Stoffel-Wagner B, Bertsch T, Hartmann T, Maier W, von Bergmann K: The plant sterol brassicasterol as additional CSF biomarker in Alzheimer’s disease. Acta Psychiatr Scand. 2011, 124 (3): 184-192. 10.1111/j.1600-0447.2011.01713.x.
Article
CAS
PubMed
Google Scholar
Lee HE, Kim DH, Park SJ, Kim JM, Lee YW, Jung JM, Lee CH, Hong JG, Liu X, Cai M: Neuroprotective effect of sinapic acid in a mouse model of amyloid beta(1–42) protein-induced Alzheimer’s disease. Pharmacol Biochem Behav. 2012, 103 (2): 260-266. 10.1016/j.pbb.2012.08.015.
Article
CAS
PubMed
Google Scholar
Kim DH, Yoon BH, Kim YW, Lee S, Shin BY, Jung JW, Kim HJ, Lee YS, Choi JS, Kim SY: The seed extract of Cassia obtusifolia ameliorates learning and memory impairments induced by scopolamine or transient cerebral hypoperfusion in mice. J Pharmacol Sci. 2007, 105 (1): 82-93. 10.1254/jphs.FP0061565.
Article
CAS
PubMed
Google Scholar
He L, Li HT, Guo SW, Liu LF, Qiu JB, Li F, Cai BC: Inhibitory effects of sinapine on activity of acetylcholinesterase in cerebral homogenate and blood serum of rats. Zhongguo Zhong Yao Za Zhi. 2008, 33 (7): 813-815.
CAS
PubMed
Google Scholar
Drever BD, Anderson WG, Riedel G, Kim DH, Ryu JH, Choi DY, Platt B: The seed extract of Cassia obtusifolia offers neuroprotection to mouse hippocampal cultures. J Pharmacol Sci. 2008, 107 (4): 380-392. 10.1254/jphs.08034FP.
Article
CAS
PubMed
Google Scholar
Ryu JH, Kim DH, Kim HS, Choi JS: Republic Korean Patent Kongkae Taeho Kongbo. 2011, -039762.2011
Google Scholar
Anilakumar KR, Nagaraj NS, Santhanam K: Reduction of hexachlorocyclohexane-induced oxidative stress and cytotoxicity in rat liver by Emblica officinalis gaertn. Indian J Exp Biol. 2007, 45 (5): 450-454.
CAS
PubMed
Google Scholar
Vasudevan M, Parle M: Effect of Anwala churna (Emblica officinalis GAERTN.): an ayurvedic preparation on memory deficit rats. Yakugaku Zasshi. 2007, 127 (10): 1701-1707. 10.1248/yakushi.127.1701.
Article
CAS
PubMed
Google Scholar
Vasudevan M, Parle M: Memory enhancing activity of Anwala churna (Emblica officinalis Gaertn.): an Ayurvedic preparation. Physiol Behav. 2007, 91 (1): 46-54. 10.1016/j.physbeh.2007.01.016.
Article
CAS
PubMed
Google Scholar
Golechha M, Bhatia J, Arya DS: Studies on effects of Emblica officinalis (Amla) on oxidative stress and cholinergic function in scopolamine induced amnesia in mice. J Environ Biol. 2012, 33 (1): 95-100.
PubMed
Google Scholar
Yu MS, Wong AY, So KF, Fang JN, Yuen WH, Chang RC: New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway. Brain Res. 2007, 1153: 221-230.
Article
CAS
PubMed
Google Scholar
Yu M-S, Lai S-W, Lin K-F, Fang J-N, Yuen W-H, Chang R-C: Characterization of polysaccharides from the flowers of Nerium indicum and their neuroprotective effects. Int J Mol Med. 2004, 14 (5): 917-924.
CAS
PubMed
Google Scholar
Addington OC, Newman RA: Method of treating neurological conditions with cardiac glycosides. 2011, vol. WO 2011085307 A1 20110714: PCT Int. Appl
Google Scholar
Gholamhoseinian A, Moradi MN, Sharifi-Far F: Screening the methanol extracts of some Iranian plants for acetylcholinesterase inhibitory activity. Res Pharm Sci. 2009, 4 (2): 105-112.
CAS
PubMed
PubMed Central
Google Scholar
Azzubaidi M, Saxena A, Talib N, Ahmed Q, Dogarai B: Protective effect of treatment with black cumin oil on spatial cognitive functions of rats that suffered global cerebrovascular hypoperfusion. Acta Neurobiol Exp (Wars). 2012, 72 (2): 154-165.
Google Scholar
Parray SA, Bhat J-U, Ahmad G, Jahan N, Sofi G, IFS M:Ruta graveolens: from Traditional System of Medicine to Modern Pharmacology: an Overview.Am J Pharm Tech Res. 2012, 2 (2): 239-252.
Google Scholar
Wszelaki N, Kuciun A, Kiss AK: Screening of traditional European herbal medicines for acetylcholinesterase and butyrylcholinesterase inhibitory activity. Acta Pharm. 2010, 60 (1): 119-128.
Article
CAS
PubMed
Google Scholar
Tildesley NT, Kennedy DO, Perry EK, Ballard CG, Wesnes KA, Scholey AB: Positive modulation of mood and cognitive performance following administration of acute doses of Salvia lavandulaefolia essential oil to healthy young volunteers. Physiol Behav. 2005, 83 (5): 699-709. 10.1016/j.physbeh.2004.09.010.
Article
CAS
PubMed
Google Scholar
Proestos C, Sereli D, Komaitis M: Determination of phenolic compounds in aromatic plants by RP-HPLC and GC-MS. Food Chem. 2006, 95 (1): 44-52. 10.1016/j.foodchem.2004.12.016.
Article
CAS
Google Scholar
Quijano-Abril MA, Callejas-Posada R, Miranda-Esquivel DR: reas of endemism and distribution patterns for neotropical Piper species (Piperaceae). J Biogeog. 2006, 33: 1266-1278. 10.1111/j.1365-2699.2006.01501.x.
Article
Google Scholar
Selvendiran K, Singh JP, Krishnan KB, Sakthisekaran D: Cytoprotective effect of piperine against benzo[a]pyrene induced lung cancer with reference to lipid peroxidation and antioxidant system in Swiss albino mice. Fitoterapia. 2003, 74 (1–2): 109-115.
Article
CAS
PubMed
Google Scholar
Srinivasan K: Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Crit Rev Food Sci. 2007, 47 (8): 735-748. 10.1080/10408390601062054.
Article
CAS
Google Scholar
Mahdy K, Shaker O, Wafay H, Nassar Y, Hassan H, Hussein A: Effect of some medicinal plant extracts on the oxidative stress status in Alzheimer’s disease induced in rats. Europ Rev Med Pharmacol Sci. 2012, 16: 331-342.
Google Scholar
Sancheti S, Sancheti S, Um B-H, Seo S-Y: 1,2,3,4,6-penta-O-galloyl-β-D-glucose: a cholinesterase inhibitor from Terminalia chebula. South Afr J Bot. 2010, 76 (2): 285-288. 10.1016/j.sajb.2009.11.006.
Article
CAS
Google Scholar
Dua JS, Prasad DN, Tripathi AC, Gupta R: Role of traditional medicine in neuropsychopharmacology. Asian J Pharmaceut Clin Res. 2009, 2 (2): 72-76.
CAS
Google Scholar
Verma N, Vinayak M: Effect of Terminalia arjuna on antioxidant defense system in cancer. Mol Biol Rep. 2009, 36 (1): 159-164. 10.1007/s11033-008-9279-3.
Article
CAS
PubMed
Google Scholar