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  1. There is growing interest in the use of complementary and alternative medicine (CAM) throughout the world, however previous research done in Japan has focused primarily on CAM use in major cities. The purpose ...

    Authors: Gregory Shumer, Sara Warber, Satoko Motohara, Ayaka Yajima, Melissa Plegue, Matthew Bialko, Tomoko Iida, Kiyoshi Sano, Masaki Amenomori, Tsukasa Tsuda and Michael D Fetters
    Citation: BMC Complementary and Alternative Medicine 2014 14:360
    Content type: Research article Published on:

  2. Danggui (Radix Angelicae Sinensis) is an herb often used in Traditional Chinese medicine. It is used to promote blood flow and has been used in the treatment of myocardial ischemia-reperfusion injury in animal m...

    Authors: Chih-Yang Huang, Wei-Wen Kuo, Chia-Hua Kuo, Fuu-Jen Tsai, Peng-Yu Liu and Dennis Jine-Yuan Hsieh
    Citation: BMC Complementary and Alternative Medicine 2014 14:358
    Content type: Research article Published on:

  3. Crataeva nurvala Buch.-Ham. (Family: Capparidaceae) is widely used as anti-inflammatory, contraceptive, laxative, lithotropic, febrifuge and as tonic in traditional medicine. This study evaluated the antinocicep...

    Authors: Md Moniruzzaman and Mohammad Zafar Imam
    Citation: BMC Complementary and Alternative Medicine 2014 14:354
    Content type: Research article Published on:

  4. Angiogenesis, which is initiated by certain tumor micro-environmental conditions and diverse protein factors, plays a pivotal role during tumor development and metastasis. Therefore, many efforts have been mad...

    Authors: Jin-Mu Yi, Jong-Shik Park, Jun Lee, Jin Tae Hong, Ok-Sun Bang and No Soo Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:353
    Content type: Research article Published on:

  5. Excessive bone resorption by osteoclasts causes pathological bone destruction, seen in various bone diseases. There is accumulating evidence that certain herbal extracts have beneficial effects on bone metabol...

    Authors: Hyunil Ha, Ki-Shuk Shim, Taesoo Kim, Chung-Jo Lee, Ji Hyung Park, Han Sung Kim and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2014 14:352
    Content type: Research article Published on:

  6. Postprandial hyperglycemia is a known risk factor for the development of several health disorders including type 2 diabetes, obesity, oxidative stress, and cardiovascular diseases. One encouraging approach for...

    Authors: Vickram Beejmohun, Marie Peytavy-Izard, Cyril Mignon, Delphine Muscente-Paque, Xavier Deplanque, Christophe Ripoll and Nicolas Chapal
    Citation: BMC Complementary and Alternative Medicine 2014 14:351
    Content type: Research article Published on:

  7. Metabonomics is a useful tool for studying mechanisms of drug treatment using systematic metabolite profiles. Ginsenosides Rg1 and Rb1, ophiopogonin D, and schizandrin are the main bioactive components of a tr...

    Authors: Miaomiao Jiang, Liyuan Kang, Yi Wang, Xiaoping Zhao, Xuan Liu, Lei Xu and Zheng Li
    Citation: BMC Complementary and Alternative Medicine 2014 14:350
    Content type: Research article Published on:

  8. Among underserved, largely minority women who were breast cancer survivors, this pilot project was designed to evaluate the quality of life outcomes of a 20 week Contemplative Self-Healing Program.

    Authors: Mary E Charlson, Joseph Loizzo, Alyson Moadel, Miles Neale, Chayim Newman, Erin Olivo, Emily Wolf and Janey C Peterson
    Citation: BMC Complementary and Alternative Medicine 2014 14:349
    Content type: Research article Published on:

  10. Asparagus gracilis subspecie of Asparagus capitatus Baker, is described as food and medicine for various ailments. In this study we investigated, its phenolic constituents, in vitro antioxidant potential against...

    Authors: Naseer Ali Shah, Muhammad Rashid Khan, Saadia Sattar, Bushra Ahmad and Bushra Mirza
    Citation: BMC Complementary and Alternative Medicine 2014 14:347
    Content type: Research article Published on:

  11. The present study was aimed to investigate the antinociceptive and anti-inflammatory activity of the Curcuma zedoaria (family Zingiberaceae) ethanolic rhizome extract in laboratory using both in vitro and in vivo

    Authors: H M Arif Ullah, Sayera Zaman, Fatematuj Juhara, Lucky Akter, Syed Mohammed Tareq, Emranul Haque Masum and Rajib Bhattacharjee
    Citation: BMC Complementary and Alternative Medicine 2014 14:346
    Content type: Research article Published on:

  12. Acupuncture is an effective complement to pharmacological therapy in the alleviation of chronic pelvic inflammatory disease (PID). It has mild or no side effects; however, a minimum of 3 months of therapy is r...

    Authors: Yudan Liang and Dongfang Gong
    Citation: BMC Complementary and Alternative Medicine 2014 14:345
    Content type: Research article Published on:

  13. Guibi-tang (GBT), a traditional herbal formula, mainly has been shown to possess immune regulation, antioxidant and protective effect of the gastric mucosa. Constituent herbs of GBT are frequently used to trea...

    Authors: Nam-Hui Yim, Aeyung Kim, Chun Liang, Won-Kyung Cho and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2014 14:344
    Content type: Research article Published on:

  14. The oral cavity is the store house of different species of microorganisms that are continuously engaged in causing diseases in the mouth. The present study was conducted to evaluate the antibacterial potential...

    Authors: Jayanta Kumar Patra, Eun Sil Kim, Kyounghee Oh, Hyeon-Jeong Kim, Yangseon Kim and Kwang-Hyun Baek
    Citation: BMC Complementary and Alternative Medicine 2014 14:343
    Content type: Research article Published on:

  15. The Cheilanthes albomarginata Clarke (CA), a fern belonging to Pteridaceae family, is found mainly in India, Nepal, Pakistan and Bhutan at an altitude of 1300–2700 m. It grows mostly in the rock crevices on slope...

    Authors: Ramakanta Lamichhane, Se-Gun Kim, Amrit Poudel, Dipak Sharma, Kyung-Hee Lee and Hyun-Ju Jung
    Citation: BMC Complementary and Alternative Medicine 2014 14:342
    Content type: Research article Published on:

  16. Acupuncture and moxibustion are used to treat pruritus and atopic dermatitis. However, whether cold stimulation (defined as that the temperature conducted under skin temperature) of acupoints affects itching i...

    Authors: Kao-Sung Tsai, Yung-Hsiang Chen, Huey-Yi Chen, Ein-Yiao Shen, Yu-Chen Lee, Jui-Lung Shen, San-Yuan Wu, Jaung-Geng Lin, Yi-Hung Chen and Wen-Chi Chen
    Citation: BMC Complementary and Alternative Medicine 2014 14:341
    Content type: Research article Published on:

  17. The search for natural products as potential cytotoxic agents has yielded promising candidates. However multidrug resistance (MDR) is still a major hurdle for patients receiving chemotherapy. In the present st...

    Authors: Victor Kuete, Patrick Y Ango, Samuel O Yeboah, Armelle T Mbaveng, Renameditswe Mapitse, Gilbert DWF Kapche, Bonaventure T Ngadjui and Thomas Efferth
    Citation: BMC Complementary and Alternative Medicine 2014 14:340
    Content type: Research article Published on:

  18. This study aims to investigate the anti-inflammatory effect of biologically active phospholipids (BAP) used in preparations for clinical practice in humans. Until date, except anti-neoplastic ability, little i...

    Authors: Monika Vicenova, Katerina Nechvatalova, Katarina Chlebova, Zdenka Kucerova, Lenka Leva, Hana Stepanova and Martin Faldyna
    Citation: BMC Complementary and Alternative Medicine 2014 14:339
    Content type: Research article Published on:

  19. Acupuncture is an alternative therapy that is widely used to treat various neurodegenerative diseases and effectively improve cognitive and memory impairment. The aim of this study was to examine whether acupu...

    Authors: Bombi Lee, Bongjun Sur, Jaegul Shim, Dae-Hyun Hahm and Hyejung Lee
    Citation: BMC Complementary and Alternative Medicine 2014 14:338
    Content type: Research article Published on:

  20. Emergence of drug-resistant strains of Candida and inefficiency of conventional antifungal therapy has necessitated the search for alternative and new antifungal agents. Inhibition of virulence and biofilm are th...

    Authors: Mohd SA Khan, Iqbal Ahmad, Swaranjit S Cameotra and Francien Botha
    Citation: BMC Complementary and Alternative Medicine 2014 14:337
    Content type: Research article Published on:

  22. Xanthosoma violaceum is commonly observed in fallow areas of Bangladesh but almost no scientific studies exist on this plant. Rural people consume the plant on a frequent basis. The objective of this study was t...

    Authors: Mohammad Faisal, Ahamed Ismail Hossain, Shahnaz Rahman, Rownak Jahan and Mohammed Rahmatullah
    Citation: BMC Complementary and Alternative Medicine 2014 14:335
    Content type: Research article Published on:

  23. Jatropha curcas (JCP1), Pyrenacantha staudtii (PS), Picralima nitida (ZI) and Jatropha gossypifolia (JCP2) are plants used in the African folklore for the treatment of various cancers.

    Authors: Nadja Engel, Abiodun Falodun, Juliane Kühn, Udo Kragl, Peter Langer and Barbara Nebe
    Citation: BMC Complementary and Alternative Medicine 2014 14:334
    Content type: Research article Published on:

  24. Knee osteoarthritis (OA) causes pain and long-term disability with annual healthcare costs exceeding $185 billion in the United States. Few medical remedies effectively influence the course of the disease. Fin...

    Authors: Chenchen Wang, Maura D Iversen, Timothy McAlindon, William F Harvey, John B Wong, Roger A Fielding, Jeffrey B Driban, Lori Lyn Price, Ramel Rones, Tressa Gamache and Christopher H Schmid
    Citation: BMC Complementary and Alternative Medicine 2014 14:333
    Content type: Study protocol Published on:

  25. Authors: John E Lewis, Angelica B Melillo, Eduard Tiozzo, Lawrence Chen, Susanna Leonard, Mark Howell, Janelle Diaz, Kathy Gonzalez, Judi M Woolger, Janet Konefal, Elaine Paterson and David Barnes
    Citation: BMC Complementary and Alternative Medicine 2014 14:332
    Content type: Erratum Published on:

    The original article was published in BMC Complementary and Alternative Medicine 2014 14:43

  26. Partial or total flap necrosis after flap transplantation is sometimes encountered in reconstructive surgery, often as a result of a period of hypoxia that exceeds the tolerance of the flap tissue. The purpose...

    Authors: Zihan Xu, Lijun Wu, Yaowen Sun, Yadong Guo, Gaoping Qin, Shengzhi Mu, Ronghui Fan, Benfeng Wang, Wenjie Gao and Zhenxin Zhang
    Citation: BMC Complementary and Alternative Medicine 2014 14:331
    Content type: Research article Published on:

  27. Dictamnus dasycarpus is widely used as a traditional remedy for the treatment of eczema, rheumatism, and other inflammatory diseases in Asia. The current study investigates the molecular mechanism of anti-inflam...

    Authors: Chiranjit Ghosh, Bora Hong, Subhasis Batabyal, Tae-Il Jeon, Seung-Hak Yang and Seong Gu Hwang
    Citation: BMC Complementary and Alternative Medicine 2014 14:330
    Content type: Research article Published on:

  28. Biofilm bacteria are relatively more resistant to antibiotics. The escalating trend of antibiotic resistance higlights the need for evaluating alternative potential therapeutic agents with antibacterial proper...

    Authors: Eric N Hammond, Eric S Donkor and Charles A Brown
    Citation: BMC Complementary and Alternative Medicine 2014 14:329
    Content type: Research article Published on:

  30. Darjeeling tea, a most popular variety of black tea, though consumed by the people in different parts of world but its beneficial health effects have not been investigated in details. In this study, the antimu...

    Authors: Udayan Bhattacharya, Shanta Adak, Niladri Shekhar Majumder, Biswajit Bera and Ashok K Giri
    Citation: BMC Complementary and Alternative Medicine 2014 14:327
    Content type: Research article Published on:

  31. Herbal therapies are potential alternatives and adjuncts for depression treatment. The present study aims to investigate the antidepressant-like effects of hydroalcoholic Hemerocallis citrina extracts and its pot...

    Authors: Bingjian Du, Xiaoshuang Tang, Fei Liu, Chunyue Zhang, Guanghua Zhao, Fazheng Ren and Xiaojing Leng
    Citation: BMC Complementary and Alternative Medicine 2014 14:326
    Content type: Research article Published on:

  32. Onchocerciasis caused by Onchocerca volvulus is the world’s second leading infectious cause of blindness. There is currently no cure for the disease. Ivermectin, the current drug of choice is only microfilaricida...

    Authors: Moses Samje, Jonathan Metuge, James Mbah, Brice Nguesson and Fidelis Cho-Ngwa
    Citation: BMC Complementary and Alternative Medicine 2014 14:325
    Content type: Research article Published on:

  33. Acupuncture has been shown to reduce pain, and acupuncture-induced sensation may be important for this analgesia. In addition, cognitive coping strategies can influence sensory perception. However, the role of...

    Authors: Jeungchan Lee, Vitaly Napadow and Kyungmo Park
    Citation: BMC Complementary and Alternative Medicine 2014 14:324
    Content type: Research article Published on:

  34. Electroacupuncture (EA) is a traditional Chinese medicine treatment guided by meridian theory. As it gradually gains more worldwide acceptance, a clarification of its mechanisms is extremely urgent. We observe...

    Authors: Shu-Xia Zheng, Xiao-Hua Pan, Jin-Sen Xu, Chun-Ying Xiu, Ya-Qin Dong and Xiaoxiang Zhu
    Citation: BMC Complementary and Alternative Medicine 2014 14:323
    Content type: Research article Published on:

  35. Cancer immunotherapy requires proper manipulation of the immune system, lymphocytes in particular, in order to identify and destroy the cancer cells as non-self. In this study we investigated the effect of the...

    Authors: Farid Saleh, Raj Raghupathy, Sami Asfar, Medhat Oteifa and Noha Al-Saleh
    Citation: BMC Complementary and Alternative Medicine 2014 14:322
    Content type: Research article Published on:

  37. Complementary and alternative medicine (CAM) is widely used in Germany, with some treatments eligible for health insurance reimbursements. CAM encourages patients to play an active role in their healing proces...

    Authors: Lena Schützler and Claudia M Witt
    Citation: BMC Complementary and Alternative Medicine 2014 14:320
    Content type: Research article Published on:

  38. Plants are the valuable source of natural products with important medicinal properties. Most of the approved anti cancer drugs have a natural product origin or are natural products. Retinoblastoma is the most ...

    Authors: Naresh Kumar, Gangappa D, Geetika Gupta and Roy Karnati
    Citation: BMC Complementary and Alternative Medicine 2014 14:319
    Content type: Research article Published on:

  39. Extraction prior to component analysis is the primary step in the recovery and isolation of bioactive phytochemicals from plant materials.

    Authors: Ali Ghasemzadeh, Hawa ZE Jaafar, Ehsan Karimi and Asmah Rahmat
    Citation: BMC Complementary and Alternative Medicine 2014 14:318
    Content type: Research article Published on:

  40. The study randomly screened leaf extracts of several hundred southern African tree species against important microbial pathogens to determine which taxa have the highest activity and may yield useful products ...

    Authors: Elisabeth Pauw and Jacobus Nicolaas Eloff
    Citation: BMC Complementary and Alternative Medicine 2014 14:317
    Content type: Research article Published on:

  41. Cumulating evidence has revealed the effectiveness of acupuncture therapy in relieving pain via immunoregulation. However, its underlying mechanism remains unknown. The present study was designed to determine ...

    Authors: Yong-Hui Gao, Jun-Ying Wang, Li-Na Qiao, Shu-Ping Chen, Lian-Hong Tan, Qiu-Ling Xu and Jun-Ling Liu
    Citation: BMC Complementary and Alternative Medicine 2014 14:316
    Content type: Research article Published on:

  42. The purpose of present study was to examine biological and psychological characteristics of people according to the Sasang typology, which is popular in Korea. We evaluated the Sasang Personality Questionnaire...

    Authors: Soo Jin Lee, Soo Hyun Park, C Robert Cloninger, Yun Hee Kim, Minwoo Hwang and Han Chae
    Citation: BMC Complementary and Alternative Medicine 2014 14:315
    Content type: Research article Published on:

  43. Malaria is one of the most important tropical diseases and the greatest cause of hospitalization and death. Recurring problems of drug resistance are reinforcing the need for finding new antimalarial drugs. In...

    Authors: Tigist Mohammed, Berhanu Erko and Mirutse Giday
    Citation: BMC Complementary and Alternative Medicine 2014 14:314
    Content type: Research article Published on:

  44. Radix Astragali is famous for its beneficial effect on inflammation associated diseases. This study was to assess the efficacy of astragalosides (AST) extracted from Radix Astragali, on the progression of expe...

    Authors: Yi-Xin He, Min Du, Hai-Lian Shi, Fei Huang, Hong-Shuai Liu, Hui Wu, Bei-Bei Zhang, Wei Dou, Xiao-Jun Wu and Zheng-Tao Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:313
    Content type: Research article Published on:

  45. The utility of acupuncture in managing osteoarthritis symptoms is uncertain. Trial results are conflicting and previous systematic reviews may have overestimated the benefits of acupuncture.

    Authors: Taru Manyanga, Maria Froese, Ryan Zarychanski, Ahmed Abou-Setta, Carol Friesen, Michael Tennenhouse and Barbara L Shay
    Citation: BMC Complementary and Alternative Medicine 2014 14:312
    Content type: Research article Published on:

  46. The aging process involves a decline in immune functioning that renders elderly people more vulnerable to disease. In residential programs for the aged, it is vital to diminish their risk of disease, promote t...

    Authors: Abilio Reig-Ferrer, Rosario Ferrer-Cascales, Ana Santos-Ruiz, Adolfo Campos-Ferrer, Alvaro Prieto-Seva, Irene Velasco-Ruiz, Maria Dolores Fernandez-Pascual and Natalia Albaladejo-Blazquez
    Citation: BMC Complementary and Alternative Medicine 2014 14:311
    Content type: Research article Published on:

  47. Foeniculum vulgare locally known as ensilal, is an aromatic plant widely cultivated in temperate and tropical regions. The anti-anxiety activity of the crude extract of F. vulgare has been reported. However, the...

    Authors: Miraf Mesfin, Kaleab Asres and Workineh Shibeshi
    Citation: BMC Complementary and Alternative Medicine 2014 14:310
    Content type: Research article Published on:

  48. Essential oils (EOs) are complex mixtures of secondary metabolites from various plants. It has been shown that several EOs, or their constituents, have inhibitory activity against trypanosomatid protozoa. Thus...

    Authors: Camila Maria O Azeredo, Thalita Gilda Santos, Beatriz Helena Lameiro de Noronha Sales Maia and Maurilio José Soares
    Citation: BMC Complementary and Alternative Medicine 2014 14:309
    Content type: Research article Published on:

  49. The dopamine system, which is involved in drug dependence, can be damaged by opioid abuse. However, current clinical medicines cannot reverse these damages in the brain, which are believed to be a key reason f...

    Authors: Jin-Long Gao, Shao-Ang Tu, Jia Liu, Jin-Ming Zhang, Yiyun Huang, Mei Han and Jian-Hui Liang
    Citation: BMC Complementary and Alternative Medicine 2014 14:308
    Content type: Research article Published on:

  50. The prevalence and socioeconomic cost of late life depression (LLD) is on the rise, while the response rate to antidepressant trials remains poor. Various mind-body therapies are being embraced by patients as ...

    Authors: Zareen Amtul, Amanda Arena, Hussein Hirjee, Zaineb U Khan, Pramudith M Maldeniya, Ronnie I Newman, Amer M Burhan, Stephen Wetmore and Akshya Vasudev
    Citation: BMC Complementary and Alternative Medicine 2014 14:307
    Content type: Study protocol Published on:
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