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  1. Multi-drug resistance of Gram-negative bacteria constitutes a major obstacle in the antibacterial fight worldwide. The discovery of new and effective antimicrobials and/or resistance modulators is necessary to...

    Authors: Jackson A. Seukep, Louis P. Sandjo, Bonaventure T. Ngadjui and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2016 16:193
    Content type: Research article Published on:

  2. The use of Complementary and Alternative Medicine (CAM) has been increasing over the years. A recent review of adverse event reports (AERs) associated with CAM in Singapore found a notable number of AERs submi...

    Authors: Desmond Chun Hwee Teo, Patricia Suet Leng Ng, Siew Har Tan, Adena Theen Lim, Dorothy Su Lin Toh, Sui Yung Chan and Han Hui Cheong
    Citation: BMC Complementary and Alternative Medicine 2016 16:192
    Content type: Research article Published on:

  3. Khaya grandifoliola (Meliaceae) and Entada africana (Fabaceae) are traditionally used in Bamun (a western tribe of Cameroon) traditional medicine for the treatment of liver related dis...

    Authors: Frédéric Nico Njayou, Arnaud Fondjo Kouam, Brice Fredy Nemg Simo, Angèle Nkouatchoua Tchana and Paul Fewou Moundipa
    Citation: BMC Complementary and Alternative Medicine 2016 16:190
    Content type: Research article Published on:

  5. Drynaria quercifolia L. (Family- Polypodiaceae) is a fern grows in Bangladesh used in traditional healing by the Garo tribe of Mymensingh district. In the current study, rhizomes and f...

    Authors: Farjana Rahman Chaity, Mahbuba Khatun and Mohammad Sharifur Rahman
    Citation: BMC Complementary and Alternative Medicine 2016 16:184
    Content type: Research article Published on:

  6. To extract, purify, and identify the effective constituents of aqueous extract of Fructus Chebulae Immaturus, and analyze the bactericidal effects of total tannins.

    Authors: Kun Li, Yue Lin, Bin Li, Taowen Pan, Fei Wang, Ruqiang Yuan, Jianjun Ji, Yunpeng Diao and Shouyu Wang
    Citation: BMC Complementary and Alternative Medicine 2016 16:183
    Content type: Research article Published on:

  7. High plasma concentration of low-density lipoprotein cholesterol (LDL-c) plays a significant role in the incidence of atherosclerosis and coronary heart diseases. The aim of this study was to investigate the m...

    Authors: Nora A. Bawazeer, Hani Choudhry, Mazin A. Zamzami, Wesam H. Abdulaal, Bruce Middleton and Said S. Moselhy
    Citation: BMC Complementary and Alternative Medicine 2016 16:182
    Content type: Research article Published on:

  8. Menopause is characterized by a decrease in life quality due to the appearance of uncomfortable symptoms. Nowadays, Understanding menopause-associated pathophysiology and developing new strategies to improve t...

    Authors: Jian-mei Zhang, Jin Li, Er-wei Liu, Hong Wang, Guan-wei Fan, Yue-fei Wang, Yan Zhu, Shang-wei Ma and Xiu-mei Gao
    Citation: BMC Complementary and Alternative Medicine 2016 16:181
    Content type: Research article Published on:

  9. Viola yedoensis (VY, Violaceae) is a popular medicinal herb used in traditional eastern medicine for treating lots of diseases, including inflammation and its related symptoms. However...

    Authors: Yun Hee Jeong, You-Chang Oh, Won-Kyung Cho, Hyeji Shin, Ki Yong Lee and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2016 16:180
    Content type: Research article Published on:

  10. Gurigumu-7 is an important traditional Mongolian medicine frequently used for liver diseases. However, the pharmacological effects and the bioactive constituents are not well understood.

    Authors: Haiyan Xu, Qiong Ma, Jiannan Ma, Zhigang Wu, Yali Wang and Chaomei Ma
    Citation: BMC Complementary and Alternative Medicine 2016 16:179
    Content type: Research article Published on:

  11. Tissue damage is associated with pain, which is an alarming sign. Aspirin and morphine have been widely used in recent decades for management of pain. Medicinal herbs have been in use for treatment of differen...

    Authors: Mohammad Shoaib, Syed Wadood Ali Shah, Niaz Ali, Ismail Shah, Shafi Ullah, Mehreen Ghias, Muhammad Nawaz Tahir, Farah Gul, Sohail Akhtar, Abd Ullah, Wajid Akbar and Asad Ullah
    Citation: BMC Complementary and Alternative Medicine 2016 16:178
    Content type: Research article Published on:

  12. N-alkylamides (NAAs) are a large group of secondary metabolites occurring in more than 25 plant families which are often used in traditional medicine. A prominent active NAA is spilant...

    Authors: Lieselotte Veryser, Lien Taevernier, Tanmayee Joshi, Pratima Tatke, Evelien Wynendaele, Nathalie Bracke, Sofie Stalmans, Kathelijne Peremans, Christian Burvenich, Martijn Risseeuw and Bart De Spiegeleer
    Citation: BMC Complementary and Alternative Medicine 2016 16:177
    Content type: Research article Published on:

  13. There is increasing evidence that complementary medicine (CM) services are being used by a substantial proportion of the Australian population and this topic has attracted keen interest from primary health car...

    Authors: Rebecca Reid, Amie Steel, Jon Wardle, Andrea Trubody and Jon Adams
    Citation: BMC Complementary and Alternative Medicine 2016 16:176
    Content type: Research article Published on:

  14. Methanol extract of Bauhinia purpurea L. (family Fabaceae) (MEBP) possesses high antioxidant and anti-inflammatory activities and recently reported to exert hepatoprotection against paracetamol (PCM)-induced live...

    Authors: Zainul Amiruddin Zakaria, Farhana Yahya, Siti Syariah Mamat, Nur Diyana Mahmood, Nurhafizah Mohtarrudin, Muhammad Taher, Siti Selina Abdul Hamid, Lay Kek Teh and Mohd. Zaki Salleh
    Citation: BMC Complementary and Alternative Medicine 2016 16:175
    Content type: Research article Published on:

  15. Increased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), the main components extracted from Panax no...

    Authors: Hongyi Qi, Yongliang Huang, Yi Yang, Guojun Dou, Fang Wan, Wenwu Zhang, Huarong Yang, Li Wang, Chunjie Wu and Li Li
    Citation: BMC Complementary and Alternative Medicine 2016 16:174
    Content type: Research article Published on:

  16. Atopic dermatitis among children is an important issue due to relapses and skin manifestations. Traditional Chinese medicine (TCM) is commonly used to treat children with atopic dermatitis. The aim of this stu...

    Authors: Yu-Chun Chen, Yi-Hsuan Lin, Sindy Hu and Hsing-Yu Chen
    Citation: BMC Complementary and Alternative Medicine 2016 16:173
    Content type: Research article Published on:

  17. Cerebral palsy leads to many complications as well as delayed motor development, and early intensive rehabilitation in infancy, which is based on the theory of brain plasticity, is emphasized. In addition to c...

    Authors: Jeong-Eun Yoo, Young-Ju Yun, Yong-Beom Shin, Nam-kwen Kim, Soo-Yeon Kim, Myung-Jun Shin and Sun-ae Yu
    Citation: BMC Complementary and Alternative Medicine 2016 16:172
    Content type: Study protocol Published on:

  18. Hitherto no study has been published on the effect of the adjunctive administration of essential oils following scaling and root planing (SRP). This study describes the effect of a mouthrinse consisting of ess...

    Authors: Mohammad Fallah Azad, Andreas Schwiertz and Holger F. R. Jentsch
    Citation: BMC Complementary and Alternative Medicine 2016 16:171
    Content type: Research article Published on:

  19. Hericium erinaceus (HE) is a well-known mushroom in traditional Chinese food and medicine. HE extracts from the fruiting body and mycelia not only exhibit immunomodulatory, antimutagen...

    Authors: Jai-Hong Cheng, Chia-Ling Tsai, Yi-Yang Lien, Meng-Shiou Lee and Shyang-Chwen Sheu
    Citation: BMC Complementary and Alternative Medicine 2016 16:170
    Content type: Research article Published on:

  20. The ethanol extract of KOTMIN13, composed of Inula japonica Flowers, Trichosanthes kirilowii Semen, Peucedanum praeruptorum Radix, and Allium macrostemon Bulbs, was investigated for its anti-asthmatic and anti-al...

    Authors: Eujin Lee, Sun-Gun Kim, Na-Young Park, Hyo-Hyun Park, Kyu-Tae Jeong, Jongkeun Choi, In-Hae Lee, Hwadong Lee, Keuk-Jun Kim and Eunkyung Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:169
    Content type: Research article Published on:

  21. Muscle damage induced by unaccustomed or eccentric exercise results in delayed onset vascular stiffening. We tested the hypothesis that a 7-day supplementation of panax ginseng and salvia miltiorrhiza prior to an...

    Authors: Hsin-Fu Lin, Kang Tung, Chun-Chung Chou, Ching-Che Lin, Jaung-Geng Lin and Hirofumi Tanaka
    Citation: BMC Complementary and Alternative Medicine 2016 16:168
    Content type: Research article Published on:

  22. Lignosus rhinocerus (L. rhinocerus), which is known locally as Tiger Milk mushroom, is traditionally used in the treatment of asthma by indigenous communities in Malaysia. However, to ...

    Authors: M. Johnathan, S. H. Gan, M. F. Wan Ezumi, A. H. Faezahtul and A. A. Nurul
    Citation: BMC Complementary and Alternative Medicine 2016 16:167
    Content type: Research article Published on:

  23. Solanum surattense Burm. (Solanaceae) is traditionally used for management of various ailments. The study was conducted for provision of pharmacological justification for folkloric use...

    Authors: Muhammad Masood Ahmed, Shumaila Andleeb, Fatima Saqib, Musaddique Hussain, Most. Nurtaj Khatun, Bashir Ahmad Ch and Hafizur Rahman
    Citation: BMC Complementary and Alternative Medicine 2016 16:166
    Content type: Research article Published on:

  24. Glucocorticoid-induced osteoporosis (GIO) is one of the serious side effects which have become the most common secondary osteoporosis. The purpose of this study is to evaluate the effect of aqueous extract of ...

    Authors: Walaa G. Hozayen, Mohamed A. El-Desouky, Hanan A. Soliman, Rasha R. Ahmed and Amal K. Khaliefa
    Citation: BMC Complementary and Alternative Medicine 2016 16:165
    Content type: Research article Published on:

  26. High concentration of glucose in culture medium affects the developmental process and the quality of the pre-implantation embryo. This study examined the effects of Zuogui Wan (ZGW) supplementation on early em...

    Authors: Temaka Bai, Qianjin Feng, Shien Zhu, Xin Niu, Yingli Wang and Kaixia Xu
    Citation: BMC Complementary and Alternative Medicine 2016 16:163
    Content type: Research article Published on:

  27. Candida albicans is one of the organisms living on the human body symbiotically, but, in hosts with low immunity it becomes one of the most pathogenic fungal organisms. Combretum zeyheri has been reported to have...

    Authors: Santana Mapfunde, Simbarashe Sithole and Stanley Mukanganyama
    Citation: BMC Complementary and Alternative Medicine 2016 16:162
    Content type: Research article Published on:

  28. Neuromechanical responses to spinal manipulation therapy (SMT) have been shown to be modulated through the variation of SMT biomechanical parameters: peak force, time to peak force, and preload force. Although...

    Authors: François Nougarou, Isabelle Pagé, Michel Loranger, Claude Dugas and Martin Descarreaux
    Citation: BMC Complementary and Alternative Medicine 2016 16:161
    Content type: Research article Published on:

  29. Fermented wheat germ extract (FWGE) sold under the trade name Avemar exhibits anticancer activity in vitro and in vivo. Its mechanisms of action are divided into antiproliferative and antimetabolic effects. It...

    Authors: Christoph Otto, Theresa Hahlbrock, Kilian Eich, Ferdi Karaaslan, Constantin Jürgens, Christoph-Thomas Germer, Armin Wiegering and Ulrike Kämmerer
    Citation: BMC Complementary and Alternative Medicine 2016 16:160
    Content type: Research article Published on:

  30. Synaptic dysfunction is one of the pathological characteristics of Alzheimer's disease (AD), which is directly related to the progressive decline of cognitive function. CaMKII and CaN have been found to play i...

    Authors: Jing Shi, Xuekai Zhang, Long Yin, Mingqing Wei, Jingnian Ni, Ting Li, Pengwen Wang, Jinzhou Tian and Yongyan Wang
    Citation: BMC Complementary and Alternative Medicine 2016 16:159
    Content type: Research article Published on:

    The Retraction Note to this article has been published in BMC Complementary Medicine and Therapies 2021 21:157

  31. The emergence of drug resistant pathogens becomes a crucial problem for infectious diseases worldwide. Among these bacteria, Pseudomonas aeruginosa is one of which highly resists to many currently used drugs and ...

    Authors: Itsaraporn Utchariyakiat, Suvimol Surassmo, Montree Jaturanpinyo, Piyatip Khuntayaporn and Mullika Traidej Chomnawang
    Citation: BMC Complementary and Alternative Medicine 2016 16:158
    Content type: Research article Published on:

  32. Amaranthus (Amaranthaceae) has previously been reported to possess different bioactive phytochemicals including phenols, tannins and flavonoids. The current study was designed to evalu...

    Authors: M. Abdulla Al-Mamun, Jamiatul Husna, Masuda Khatun, Rubait Hasan, M. Kamruzzaman, K. M. F. Hoque, M. Abu Reza and Z. Ferdousi
    Citation: BMC Complementary and Alternative Medicine 2016 16:157
    Content type: Research article Published on:

  33. Excessive production of free radicals has been implicated in many diseases including cancer. They are highly reactive and bring about oxidation of biomolecules i.e., proteins, lipids and nucleic acids which ar...

    Authors: Uma Kant Sharma, Amit Kumar Sharma and Abhay K. Pandey
    Citation: BMC Complementary and Alternative Medicine 2016 16:156
    Content type: Research article Published on:

  34. Medicinal herb-derived drug development has become important in the relief of liver pathology. Amomun cardamomum is traditionally used therapeutically in Korea to treat various human ailments including dyspepsia,...

    Authors: Dong-Woo Lim, Hyuck Kim, Ju-Yeon Park, Jai-Eun Kim, Jin-Young Moon, Sun-Dong Park and Won-Hwan Park
    Citation: BMC Complementary and Alternative Medicine 2016 16:155
    Content type: Research article Published on:

  35. Apoptosis of endothelial cells caused by reactive oxygen species plays an important role in ischemia/reperfusion injury after cerebral infarction. Buyang Huanwu Decoction (BYHWD) has been used to treat stroke ...

    Authors: Jian Shen, Yu Zhu, Kaiyuan Huang, Hao Jiang, Chengzhang Shi, Xiaoxing Xiong, Renya Zhan and Jianwei Pan
    Citation: BMC Complementary and Alternative Medicine 2016 16:154
    Content type: Research article Published on:

  36. Chewing fresh leaves of the khat plant (Catha edulis forsk) is a deep rooted and widespread habit in East Africa and the Middle East. Although a body of knowledge exists about the adverse effects of khat on healt...

    Authors: Tegegne Bogale, Epherm Engidawork and Engida Yisma
    Citation: BMC Complementary and Alternative Medicine 2016 16:153
    Content type: Research article Published on:

  37. Sweet potato (Ipomoea batatas L.) is one of the most important consumed crops in many parts of the world because of its economic importance and content of health-promoting phytochemicals.

    Authors: Ali Ghasemzadeh, Daryush Talei, Hawa Z. E. Jaafar, Abdul Shukor Juraimi, Mahmud Tengku Muda Mohamed, Adam Puteh and Mohd Ridzwan A. Halim
    Citation: BMC Complementary and Alternative Medicine 2016 16:152
    Content type: Research article Published on:

  38. We previously reported the anti-estrogenic activity of the brown seaweed, Fucus vesiculosus. The present study aimed to further investigate its anti-estrogenic modes of action and to assess other potentially biol...

    Authors: Jianqing Zhang, Jacques E. Riby, Lucia Conde, William E. Grizzle, Xiangqin Cui and Christine F. Skibola
    Citation: BMC Complementary and Alternative Medicine 2016 16:151
    Content type: Research article Published on:

  39. San Huang Shel Shin Tang (SHSST) is a traditional herbal decoction used as a hepato-protective agent and is composed of Rheum officinale Baill, Scutellaria baicalnsis Geprgi and Coptis chinensis Franch (2:1:1 w/w...

    Authors: Yu-Lan Yeh, Wei-Jen Ting, Wei-Wen Kuo, Hsi-Hsien Hsu, Yueh-Min Lin, Chia-Yao Shen, Chung-Ho Chang, Viswanadha Vijaya Padma, Yuhsin Tsai and Chih-Yang Huang
    Citation: BMC Complementary and Alternative Medicine 2016 16:150
    Content type: Research article Published on:

  40. Artemisia scoparia is traditionally used in the local system of medicine in kidney disorders. This study aimed at scrutinizing the nephroprotective prospective of A. scoparia methanol ...

    Authors: Moniba Sajid, Muhammad Rashid Khan, Naseer Ali Shah, Shafi Ullah, Tahira Younis, Muhammad Majid, Bushra Ahmad and Dereje Nigussie
    Citation: BMC Complementary and Alternative Medicine 2016 16:149
    Content type: Research article Published on:

  41. Mineral Pitch (MP) is a dark brown coloured humic matter originating from high altitude rocks. It is an Ayurvedic medicinal food, commonly used by the people of the Himalayan regions of Nepal and India for var...

    Authors: Kishor Pant, Parul Gupta, Preeti Damania, Ajay K. Yadav, Aanchal Gupta, Anam Ashraf and Senthil K. Venugopal
    Citation: BMC Complementary and Alternative Medicine 2016 16:148
    Content type: Research article Published on:

  42. Plant material from different organs of Pistacia terebinthus L., (Anacardiaceae) were collected in Kosovo with aim to analyze the chemical variability of the essential oils among native populations and to test th...

    Authors: Bledar Pulaj, Behxhet Mustafa, Kate Nelson, Cassandra L. Quave and Avni Hajdari
    Citation: BMC Complementary and Alternative Medicine 2016 16:147
    Content type: Research article Published on:

  43. Autophagy can result in cellular adaptation, as well as cell survival or cell death. We investigated how ginsenoside Rg1(G-Rg1) regulates the relationship between autophagy and apoptosis induced by continuous ...

    Authors: Dan Li, Jun Wang, Jincai Hou, Jianhua Fu, Dennis Chang, Alan Bensoussan and Jianxun Liu
    Citation: BMC Complementary and Alternative Medicine 2016 16:146
    Content type: Research article Published on:

  44. Clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (ADRs) among hospitalized patients. We sought to id...

    Authors: Ronald Kiguba, Sam Ononge, Charles Karamagi and Sheila M. Bird
    Citation: BMC Complementary and Alternative Medicine 2016 16:145
    Content type: Research article Published on:

  45. Although previous studies have suggested that lavender oil promote wound healing, no study has examined the molecular mechanisms of its effect. In this study, we investigated the effect of lavender oil on vari...

    Authors: Hiroko-Miyuki Mori, Hiroshi Kawanami, Hirohisa Kawahata and Motokuni Aoki
    Citation: BMC Complementary and Alternative Medicine 2016 16:144
    Content type: Research article Published on:

  46. The use of pomegranate peel is highly associated with its rich phenolic concentration. Series of drying methods are recommended since bioactive compounds are highly sensitive to thermal degradation. The study ...

    Authors: Rebogile R. Mphahlele, Olaniyi A. Fawole, Nokwanda P. Makunga and Umezuruike L. Opara
    Citation: BMC Complementary and Alternative Medicine 2016 16:143
    Content type: Research article Published on:

  47. The use of complementary and alternative medicine including herbal medicine is increasing in many countries including Ghana. However, there is paucity of research on the perspectives of patrons of herbal medic...

    Authors: Lydia Aziato and Hannah Ohemeng Antwi
    Citation: BMC Complementary and Alternative Medicine 2016 16:142
    Content type: Research article Published on:

  49. Duabanga grandiflora or known in Malaysia as Berembang Bukit, Megawasih, or Pedada Bukit, is a native plant of the Southeast Asian countries. In this study, the anti-viral properties o...

    Authors: Farhah Zaidar Abdul Malik, Zeenathul Nazariah Allaudin, Hwei San Loh, Ting Kang Nee, Homayoun Hani and Rasedee Abdullah
    Citation: BMC Complementary and Alternative Medicine 2016 16:139
    Content type: Research article Published on:

  50. Advanced glycation end-products (AGEs) play a significant role in the development and progression of vascular complication in diabetes. Anthocyanin has been recently reported to possess antiglycating activity....

    Authors: Thavaree Thilavech, Sathaporn Ngamukote, Damien Belobrajdic, Mahinda Abeywardena and Sirichai Adisakwattana
    Citation: BMC Complementary and Alternative Medicine 2016 16:138
    Content type: Research article Published on:
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