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Retraction Note: Herbal formula GAPT prevents beta amyloid deposition induced Ca2+/Calmodulin-dependent protein kinase II and Ca2+/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice

The Original Article was published on 01 June 2016

Retraction Note: BMC Complement Altern Med 16, 159 (2016)

https://doi.org/10.1186/s12906-016-1144-7

The Editor has retracted this article [1]. Concerns were raised with a number of figures, specifically:

  • Figure 1: the panels for Control, APP+D, APP+Gl and APP+Gh appear to be identical to the panels for Control, APP+D, APP+Gl and APP of Fig. 1 [2].

  • Figure 2: the bottom right panel appears to be identical with the upper left panel in Fig. 5.

  • Figure 4: the upper middle panel appears to be identical with the bottom middle panel of Fig. 5

  • Figure 4: the bottom left panel appears to be identical with the bottom left panel of Fig. 5.

The Editor has therefore concluded that the data reported in this article are unreliable.

Jing Shi, Xuekai Zhang, Mingqing Wei, Jingnian Ni, Ting Li, Pengwen Wang and Jinzhou Tian do not agree to this retraction. Long Yin has not responded to any correspondence from the Editor about this retraction. The Editor was not able to obtain a current email address for Yongwan Wang.

References

  1. Shi, J., Zhang, X., Yin, L. et al. Herbal formula GAPT prevents beta amyloid deposition induced Ca2+/Calmodulin-dependent protein kinase II and Ca2+/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice. BMC Complement Altern Med. 2016;16:159. https://doi.org/10.1186/s12906-016-1144-7.

  2. Shi, J., Tian, J., Zhang, X. et al. A combination extract of ginseng, epimedium, polygala, and tuber curcumae increases synaptophysin expression in APPV717I transgenic mice. Chin Med. 2012;7:13. https://doi.org/10.1186/1749-8546-7-13.

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Correspondence to Jinzhou Tian.

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Shi, J., Zhang, X., Yin, L. et al. Retraction Note: Herbal formula GAPT prevents beta amyloid deposition induced Ca2+/Calmodulin-dependent protein kinase II and Ca2+/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice. BMC Complement Med Ther 21, 157 (2021). https://doi.org/10.1186/s12906-021-03331-0

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  • DOI: https://doi.org/10.1186/s12906-021-03331-0