Blanca-Lopez N, Canto MG, Blanca M. Chapter 18 - other NSAIDs reactions. In: Khan DA, Banerji A, editors. Drug Allergy Testing: Elsevier; 2018. pp. 177–96.
Google Scholar
Bevaart L, Vervoordeldonk MJ, Tak PP. Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis? Arthr Rhuem. 2010;62(8):2192–205.
Article
CAS
Google Scholar
Gan TJ. Diclofenac: an update on its mechanism of action and safety profile. Curr Med Res Opin. 2010;26(7):1715–31.
Article
CAS
Google Scholar
Bindu S, Mazumder S, Dey S, Pal C, Goyal M, Alam A, et al. Nonsteroidal anti-inflammatory drug induces proinflammatory damage in gastric mucosa through NF-κB activation and neutrophil infiltration: anti-inflammatory role of heme oxygenase-1 against nonsteroidal anti-inflammatory drug. Free Radic Biol Med. 2013;65:456–67.
Article
CAS
Google Scholar
Olayaki LA, Adeyemi WJ, Yinusa JS, Adedayo GA. Omega-3 fatty acids moderate oxidative and proinflammatory events in experimental hepatotoxicity in Wistar rats: comparison with livolin. Synergy. 2018;7:17–24.
Article
Google Scholar
Ahmed AY, Gad AM, El-Raouf OMA. Curcumin ameliorates diclofenac sodium-induced nephrotoxicity in male albino rats. J Biochem Mol Toxicol. 2017;31(10):e21951.
Article
Google Scholar
Altman R, Bosch B, Brune K, Patrignani P, Young C. Advances in NSAID development: evolution of diclofenac products using pharmaceutical technology. Drugs. 2015;75(8):859–77.
Article
CAS
Google Scholar
Aycan İ, Elpek Ö, Akkaya B, Kıraç E, Tuzcu H, Kaya S, et al. Diclofenac induced gastrointestinal and renal toxicity is alleviated by thymoquinone treatment. Food Chem Toxicol. 2018;118:795–804.
Article
CAS
Google Scholar
Näslund J, Fick J, Asker N, Ekman E, Larsson DGJ, Norrgren L. Diclofenac affects kidney histology in the three-spined stickleback (Gasterosteus aculeatus) at low µg/L concentrations. Aquat Toxicol. 2017;189:87–96.
Article
Google Scholar
Kh Z, El-Ashmawy IM, Arabia S, editors. Hepato-Renal and Hematological Effects of Diclofenac Sodium in Rats 2013.
Baravalia Y, Vaghasiya Y, Chanda S. Hepatoprotective effect of Woodfordia fruticosa Kurz flowers on diclofenac sodium induced liver toxicity in rats. Asian Pac J Trop Med. 2011;4(5):342–6.
Article
Google Scholar
Francois H, Facemire C, Kumar A, Audoly L, Koller B, Coffman T. Role of microsomal prostaglandin E synthase 1 in the kidney. J Am Soc Nephrol. 2007;18(5):1466–75.
Article
CAS
Google Scholar
Breyer MD, Hao C, Qi Z. Cyclooxygenase-2 selective inhibitors and the kidney. Curr Opin Crit Care. 2001;7(6):393–400.
Article
CAS
Google Scholar
Ungprasert P, Cheungpasitporn W, Crowson CS, Matteson EL. Individual non-steroidal anti-inflammatory drugs and risk of acute kidney injury: a systematic review and meta-analysis of observational studies. Eur J Intern Med. 2015;26(4):285–91.
Article
CAS
Google Scholar
Ng LE, Vincent AS, Halliwell B, Wong KP. Action of diclofenac on kidney mitochondria and cells. Biochem Biophys Res Commun. 2006;348(2):494–500.
Article
CAS
Google Scholar
Huang T, Zhang G, Chong S, Liu Y, Zhang N, Fang S, et al. Effects and mechanism of diclofenac degradation in aqueous solution by US/Zn0. Ultrason Sonochem. 2017;37:676–85.
Article
CAS
Google Scholar
Jena NR. DNA damage by reactive species: mechanisms, mutation and repair. J Biosci. 2012;37(3):503–17.
Article
CAS
Google Scholar
Lu YC, Yeh WC, Ohashi PS. LPS/TLR4 signal transduction pathway. Cytokine. 2008;42(2):145–51.
Article
CAS
Google Scholar
Anwar MM, Laila IMI. Protective and restorative potency of diosmin natural flavonoid compound against tramadol-induced testicular damage and infertility in male rats. Nat Prod Res. 2022:1–5. https://doi.org/10.1080/14786419.2022.2090937.
Olcina GJ, Muñoz D, Timón R, Caballero MJ, Maynar JI, Córdova A, et al. Effect of caffeine on oxidative stress during maximum incremental exercise. J sports Sci Med. 2006;5(4):621–8.
Google Scholar
Lv X, Chen Z, Li J, Zhang L, Liu H, Huang C, et al. Caffeine protects against alcoholic liver injury by attenuating inflammatory response and oxidative stress. Inflamm Res. 2010;59(8):635–45.
Article
CAS
Google Scholar
Tommerdahl KL, Hu EA, Selvin E, Steffen LM, Coresh J, Grams ME, et al. Coffee Consumption May mitigate the risk for acute kidney Injury: results from the atherosclerosis risk in Communities Study. Kidney Int Rep. 2022;7(7):1665–72.
Article
Google Scholar
Rezaie A, Pashmforosh M, Haghi M, Fazlara A, Haghighat N, Shahriari A. Hepatoprotective effect of caffeine on diethylnitrosamine-induced liver injury in rats. Bulgarian J Veterinary Med. 2014;17:183-–90.
Google Scholar
Ruhl CE, Everhart JE. Coffee and tea consumption are associated with a lower incidence of chronic liver disease in the United States. Gastroenterology. 2005;129(6):1928–36.
Article
Google Scholar
Kennedy OJ, Pirastu N, Poole R, Fallowfield JA, Hayes PC, Grzeszkowiak EJ, et al. Coffee consumption and kidney function: a mendelian randomization study. Am J Kidney Dis. 2020;75(5):753–61.
Article
CAS
Google Scholar
Ruhl CE, Everhart JE. Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States. Gastroenterology. 2005;128(1):24–32.
Article
CAS
Google Scholar
Srithongkul T, Ungprasert P. Coffee Consumption is Associated with a decreased risk of incident chronic kidney disease: a systematic review and Meta-analysis of Cohort Studies. Eur J Intern Med. 2020;77:111–6.
Article
Google Scholar
Owumi SE, Dim UJ. Biochemical alterations in diclofenac-treated rats: Effect of selenium on oxidative stress, inflammation, and hematological changes. Toxicol Res Application. 2019;3:2397847319874359.
CAS
Google Scholar
Sheth S, Sheehan K, Dhukhwa A, Al Aameri RFH, Mamillapalli C, Mukherjea D, et al. Oral administration of Caffeine exacerbates Cisplatin-Induced hearing loss. Sci Rep. 2019;9(1):9571.
Article
Google Scholar
Tice RR, Hayashi M, MacGregor JT, Anderson D, Blakey DH, Holden HE, et al. Report from the working group on the in vivo mammalian bone marrow chromosomal aberration test. Mutat Res. 1994;312(3):305–12.
Article
CAS
Google Scholar
Moore FR, Urda GA, Krishna G, Theiss JC. An in vivo/in vitro method for assessing micronucleus and chromosome aberration induction in rat bone marrow and spleen 1. Studies with cyclophosphamide. Mutat Res/Environ Mutagen Relat Subj. 1995;335(2):191–9.
CAS
Google Scholar
Drabkin DL, Austin JH. Spectrophotometric studies: I. Spectrophotometric constants for common hemoglobin. Derivatives in human, dog, and rabbit blood. J Biol Chem. 1932;98(2):719–33.
Article
CAS
Google Scholar
Onyinyechukwu AA. Haematology and Clinical Biochemistry Findings Associated with equine Diseases - a review. Notulae Scientia Biologicae. 2017;9(1):1–21. https://doi.org/10.15835/nsb919939.
Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem. 1978;86(1):271–8.
Article
CAS
Google Scholar
Moreno I, Pichardo S, Jos A, Gómez-Amores L, Mate A, Vazquez CM, et al. Antioxidant enzyme activity and lipid peroxidation in liver and kidney of rats exposed to microcystin-LR administered intraperitoneally. Toxicon. 2005;45(4):395–402.
Article
CAS
Google Scholar
Brigelius-Flohé R. Tissue-specific functions of individual glutathione peroxidases. Free Radic Biol Med. 1999;27(9–10):951–65.
Article
Google Scholar
Chiu DTY, Stults FH, Tappel AL. Purification and properties of rat lung soluble glutathione peroxidase. Biochim et Biophys Acta (BBA) - Enzymol. 1976;445(3):558–66.
Article
CAS
Google Scholar
Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite, and [15 N]nitrate in biological fluids. Anal Biochem. 1982;126(1):131–8.
Article
CAS
Google Scholar
Bancroft JD, Gamble M, Jones ML, Totty BA. Theory and practice of histological techniques. Connective tissues and stains, 15thedn Churchill Livingstone Publications. 2004:139–200.
Galati G, Tafazoli S, Sabzevari O, Chan TS, O’Brien PJ. Idiosyncratic NSAID drug induced oxidative stress. Chemico-Biol Interact. 2002;142(1–2):25–41.
Article
CAS
Google Scholar
Alabi QK, Akomolafe RO, Olukiran OS, Adeyemi WJ, Nafiu AO, Adefisayo MA, et al. The Garcinia kola biflavonoid kolaviron attenuates experimental hepatotoxicity induced by diclofenac. Pathophysiol. 2017;24(4):281–90.
Article
CAS
Google Scholar
Lazarska KE, Dekker SJ, Vermeulen NPE, Commandeur JNM. Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism. Toxicol Lett. 2018;284:70–8.
Article
CAS
Google Scholar
Dragovic S, Boerma JS, Vermeulen NP, Commandeur JN. Effect of human glutathione S-transferases on glutathione-dependent inactivation of cytochrome P450-dependent reactive intermediates of diclofenac. Chem Res Toxicol. 2013;26(11):1632–41.
Article
CAS
Google Scholar
Masubuchi Y, Nakayama S, Horie T. Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats. Hepatology (Baltimore MD). 2002;35(3):544–51.
Article
CAS
Google Scholar
Elshopakey GE, Elazab ST. Cinnamon aqueous extract attenuates diclofenac sodium and oxytetracycline mediated hepato-renal toxicity and modulates oxidative stress, cell apoptosis, and inflammation in male albino rats. Vet Sci. 2021;8(1). https://doi.org/10.3390/vetsci8010009.
Sahu N, Mishra G, Chandra HK, Nirala SK, Bhadauria M. Naringenin mitigates antituberculosis drugs induced hepatic and renal injury in rats. J Traditional Complement Med. 2020;10(1):26–35.
Article
Google Scholar
Peter SJ, Basha SK, Giridharan R, Lavinya BU, Sabina EP. Suppressive effect of Spirulina fusiformis on diclofenac-induced hepato-renal injury and gastrointestinal ulcer in Wistar albino rats: A biochemical and histological approach. Biomed Pharmacother. 2017;88:11 – 8.
Anderson AH, Yang W, Hsu CY, Joffe MM, Leonard MB, Xie D, et al. Estimating GFR among participants in the chronic renal insufficiency cohort (CRIC) study. Am J Kidney Dis. 2012;60(2):250–61.
Article
Google Scholar
Motawi TK, Ahmed SA, El-Boghdady NA, Metwally NS, Nasr NN. Impact of betanin against paracetamol and diclofenac induced hepato-renal damage in rats. Biomarkers. 2020;25(1):86–93.
Jabir NR, Islam MT, Tabrez S, Shakil S, Zaidi SK, Khan FR, et al. An insight towards anticancer potential of major coffee constituents. BioFactors. 2018;44(4):315–26.
Article
CAS
Google Scholar
Lee KJ, Choi JH, Jeong HG. Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice. Food Chem Toxicol. 2007;45(11):2118–25.
Article
CAS
Google Scholar
Guth I, Matos-Pardal CF, Ferreira-Lima R, Loureiro-Rebouças R, Sobral AC, Moraes-Marques CA, et al. Caffeine attenuates liver damage and improves neurologic signs in a rat model of hepatic encephalopathy. Revista de Gastroenterologia de Mexico. 2022;87(2):159–69.
Article
CAS
Google Scholar
Devasagayam TP, Kamat JP, Mohan H, Kesavan PC. Caffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species. Biochim Biophys Acta. 1996;1282(1):63–70.
Article
Google Scholar
Choi S, Jung S, Ko KS. Effects of Coffee extracts with different roasting degrees on antioxidant and anti-inflammatory Systems in mice. Nutrients. 2018;10(3):363.
Article
Google Scholar
Volz N, Boettler U, Winkler S, Teller N, Schwarz C, Bakuradze T, et al. Effect of Coffee Combining Green Coffee Bean constituents with typical Roasting Products on the Nrf2/ARE pathway in Vitro and in vivo. J Agric Food Chem. 2012;60:9631–41.
Article
CAS
Google Scholar
Khazaei M, Bayat PD, Ghanbari A, Khazaei S, Feizian M, Khodaei A, et al. Protective effects of subchronic caffeine administration on cisplatin induced urogenital toxicity in male mice. Indian J Exp Biol. 2012;50(9):638–44.
CAS
Google Scholar
Salomone F, Galvano F, Li Volti G. Molecular bases underlying the hepatoprotective effects of coffee. Nutrients. 2017;9(1). https://doi.org/10.3390/nu9010085.
Pashmforoosh M, Rezaie A, Haghi-Karamallah M, Fazlara A, Shahriari A, Najafzadeh H. Effects of Caffeine on Renal Toxicity. Induc Diethylnitrosamine. 2015;17(1):e1917.
Google Scholar
Temple JL, Ziegler AM. Gender differences in subjective and physiological responses to Caffeine and the role of Steroid Hormones. J Caffeine Res. 2011;1(1):41–8.
Article
CAS
Google Scholar