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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats

Fig. 5

Histopathological illustrations of liver and kidney sections stained in Hematoxylin &Eosin (100x). a, e Photomicrograph of the control group (group1) intact liver and kidney structures respectively. b, f  Photomicrograph of Dic exposed liver and kidney damages respectively (group2) indicating constricted portal area with proliferated bile duct (arrow), periportal inflammation (IF) and proliferated van Kupfer cells along with showing glomerular tuft (GT) with dilated congested blood capillaries, and dilated bowman’s space (Arrow). c, g Photomicrograph of Caf exposed liver and kidney tissues respectively (group3) showing normal intact liver and kidney structure when compared with the control group (group1). d, h photomicrograph of Dic (10 mg/kg, i.p) + Caf (15 mg/kg, orally) exposed liver and kidney sections respectively (group4) showing constricted portal area (arrow) with very mild vacuolated hepatocytes (head of arrow) and slight aggregation of inflammatory cells in lobulated glomerular tuft (GT) and convoluted tubules in addition to slight cytoplasmic atrophy (Arrow)

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