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  1. Bersama abyssinica is a common herb in Africa, with diverse medical uses in different areas. The plant is well-known in Tanzania for treating respiratory disorders such as TB, tonsillitis, bronchitis, and asthma,...

    Authors: Never Zekeya, Bertha Mamiro, Humphrey Ndossi, Rehema Chande Mallya, Mhuji Kilonzo, Alex Kisingo, Mkumbukwa Mtambo, Jafari Kideghesho and Jaffu Chilongola
    Citation: BMC Complementary Medicine and Therapies 2022 22:280
  2. Quercetin is an organic flavonoid present in several fruits and vegetables. The anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and neuroprotective properties demonstrated by th...

    Authors: Patrice Cunningham, Emma Patton, Brandon N. VanderVeen, Christian Unger, Ahmed Aladhami, Reilly T. Enos, Sarah Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy and Kandy T. Velázquez
    Citation: BMC Complementary Medicine and Therapies 2022 22:279
  3. Simiao pill module (SMM), a traditional Chinese medicine formula, has been widely used to treat gout and gouty arthritis. The goal of this study was to investigate the effects of SMM on epithelial-mesenchymal ...

    Authors: Guangxing Shui, Zheyi Cai, Feng Wang, Ting Chen, Xueyuan Huang, Yun Cai and Xiuhua Mi
    Citation: BMC Complementary Medicine and Therapies 2022 22:278
  4. Curcuminoids (CURs) are the principal ingredients of Curcuma longa L. [Zingiberaceae] (CL)—an herbal plant used in east Asia to alleviate pain and inflammation. Thus far, the therapeutic effects of CURs for knee ...

    Authors: Jie Feng, Zhao Li, Linling Tian, Panyun Mu, Yimei Hu, Feng Xiong and Xu Ma
    Citation: BMC Complementary Medicine and Therapies 2022 22:276
  5. Atopic dermatitis (AD) is a common inflammatory skin disease that compromises the skin's barrier function and capacity to retain moisture. Cnidii Fructus (CF), the dried fruits of Cnidium monnieri, has long been ...

    Authors: Shakeel Ahmad Khan, Ying Wu, Amy Sze-Man Li, Xiu-Qiong Fu and Zhi-Ling Yu
    Citation: BMC Complementary Medicine and Therapies 2022 22:275
  6. Prediabetes is a hypermetabolic syndrome with blood sugar levels falling between the normal and diabetes. People with prediabetes have a significantly increased chances of developing diabetes, cardiovascular a...

    Authors: Peng-Xiang Zhang, Lin Zeng, Lu Meng, Hui-Lin Li, Heng-Xia Zhao and De-Liang Liu
    Citation: BMC Complementary Medicine and Therapies 2022 22:274
  7. Improper use of strychnine can cause death. The aim of this study was to identify and evaluate toxic mechanisms of action associated with active compounds in strychnine using a network toxicology approach, and...

    Authors: Jialin Dai, Jiangjin Liu, Maoxin Zhang, Yanni Yu and Jie Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:273
  8. Rosa rugosa cv. Plena, a cultivar of Rosa rugosa, has a history of more than 1300 years of application in both medicine and food in China. The essential oil of Rosa rugosa cv. Plena (PREO) is one of the most freq...

    Authors: Rifat Nowshin Raka, Ding Zhiqian, Yuan Yue, Qiao Luchang, Park Suyeon, Xiao Junsong and Wu Hua
    Citation: BMC Complementary Medicine and Therapies 2022 22:272
  9. The increased global incidence of myopia requires the establishment of therapeutic approaches. This study aimed to investigate the effect of Fallopia Japonica (FJ) and Prunella vulgaris (PV) extract on myopia cau...

    Authors: Chih-Sheng Chen, Yu-An Hsu, Chia-Hung Lin, Yao-Chien Wang, En-Shyh Lin, Ching-Yao Chang, Jamie Jiin-Yi Chen, Ming-Yen Wu, Hui-Ju Lin and Lei Wan
    Citation: BMC Complementary Medicine and Therapies 2022 22:271
  10. Cistanche tubulosa is an editable and medicinal traditional Chinese herb and phenylethanoid glycosides are its major components, which have shown various beneficial effects such as anti-tumor, anti-oxidant and ne...

    Authors: Dilinazi Abudujilile, Weilan Wang, Alimu Aimaier, Lili Chang, Yuliang Dong, Yiye Wang, Xu Fan, Yu Ma, Yongli Wang, Dilinigeer Ziyayiding, Yuan Ma, Jie Lv and Jinyao Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:270
  11. Monosodium glutamate (MSG) is a food ingredient that is increasingly used commercially. MSG leads to oxidative stress, consequently suppressing steroid hormone production that causes defects in male reproducti...

    Authors: Farhad Koohpeyma, Fatemeh Gholizadeh, Hannaneh Hafezi, Mehri Hajiaghayi, Morvarid Siri, Shaghayegh Allahyari, Mohammad Hasan Maleki, Naeimehossadat Asmarian, Elahe Bayat and Sanaz Dastghaib
    Citation: BMC Complementary Medicine and Therapies 2022 22:269
  12. The WHO recommends artemisinin-based combination regimens for uncomplicated Plasmodium falciparum malaria. One such combination is artemisinin-piperaquine tablets (ATQ). ATQ has outstanding advantages in anti-mal...

    Authors: Xiaobo Li, Yueming Yuan, Yingyi Chen, Li Ru, Zheng Yuan, Zhiyong Xu, Qin Xu, Jianping Song, Guoming Li and Changsheng Deng
    Citation: BMC Complementary Medicine and Therapies 2022 22:268
  13. The emergence of antimalarial drug resistance encourages the search for new antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a medicinal plant that is used in traditional Thai ...

    Authors: Prapaporn Chaniad, Arnon Chukaew, Apirak Payaka, Arisara Phuwajaroanpong, Tachpon Techarang, Walaiporn Plirat and Chuchard Punsawad
    Citation: BMC Complementary Medicine and Therapies 2022 22:266
  14. Huntington’s disease manifests due to abnormal CAG trinucleotide expansion, in the first exon of the Huntingtin gene and disease progression involves genetic, immune, and environmental components. The pathogenesi...

    Authors: Surabhi Singh and Madhu G. Tapadia
    Citation: BMC Complementary Medicine and Therapies 2022 22:265
  15. The development of multidrug resistance (MDR) associated with the overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes antifungal therapies. The urgent need for novel agents able to ...

    Authors: Florimar Gil, Jerónimo Laiolo, Brayan Bayona-Pacheco, Richard D. Cannon, Antonio Ferreira-Pereira and María Cecilia Carpinella
    Citation: BMC Complementary Medicine and Therapies 2022 22:264
  16. Complementary medicine (CM) is frequently used by patients, but little is known about the usage of CM in surgical patients. The study aimed to elucidate the relevance of CM in surgery.

    Authors: Ann-Kathrin Lederer, Yvonne Samstag, Thomas Simmet, Tatiana Syrovets and Roman Huber
    Citation: BMC Complementary Medicine and Therapies 2022 22:263

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:304

  17. Diabetic nephropathy (DN) is one of the most important complications of type 2 diabetes (T2DM). Oxidative stress and inflammatory cytokines play an essential role in the development and progression of DN. Desp...

    Authors: Asma Jaafarinia, Behzad Kafami, Adeleh Sahebnasagh and Fatemeh Saghafi
    Citation: BMC Complementary Medicine and Therapies 2022 22:262
  18. As the largest organ, the skin has been frequently affected by trauma, chemical materials, toxins, bacterial pathogens, and free radicals. Recently, many attempts have been made to develop natural nanogels tha...

    Authors: Fatemeh Rasti, Yaser Yousefpoor, Abbas Abdollahi, Mojdeh Safari, Ghazaal Roozitalab and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:261
  19. Authors: Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa‑Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani and Gaber El‑Saber Batiha
    Citation: BMC Complementary Medicine and Therapies 2022 22:260

    The original article was published in BMC Complementary Medicine and Therapies 2022 22:227

  20. The leaf of Ceylon cinnamon (true cinnamon) is traditionally claimed for a variety of health benefits. However, reported scientific information is scanty and needs urgent attention for value addition.

    Authors: Walimuni Prabhashini Kaushalya Mendis Abeysekera, Galbada Arachchige Sirimal Premakumara, Wanigasekera Daya Ratnasooriya and Walimuni Kanchana Subhashini Mendis Abeysekera
    Citation: BMC Complementary Medicine and Therapies 2022 22:259
  21. The emergence of drug resistance among pathogens has resulted in renewed interest in bioprospecting for natural microbial products.

    Authors: Tsolanku Sidney Maliehe, Melusi Mbambo, Londeka Sibusisiwe Ngidi, Jabulani Siyabonga Emmanuel Shandu, Ofentse Jacob Pooe, Peter Masoko and Tlou Nelson Selepe
    Citation: BMC Complementary Medicine and Therapies 2022 22:258
  22. Baicalin is a generally available flavonoid with potent biological activity. The present study aimed to assess the underlying mechanism of baicalin in treatment of atherosclerosis (AS) with the help of network...

    Authors: Mingshuang Li and Conglin Ren
    Citation: BMC Complementary Medicine and Therapies 2022 22:257
  23. Propolis extracted from beehives has been conferred with natural antimicrobial and antioxidant properties. Hence, it has been recommended as a wound healing therapy. This study investigated the additive value ...

    Authors: Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar and Hoda A. Elkhenany
    Citation: BMC Complementary Medicine and Therapies 2022 22:256
  24. Diabetic wounds are one of the most important issues in diabetic patients. It seems that Juglans regia L. leaf with antioxidant and anti-inflammatory potentials can be profitable for healing of diabetic wounds. T...

    Authors: Davood Nasiry, Ali Reza Khalatbary, Alireza Ghaemi, Mohammad Ali Ebrahimzadeh and Mohammad Hossein Hosseinzadeh
    Citation: BMC Complementary Medicine and Therapies 2022 22:255
  25. Endometriosis is a common gynecological disease, and its underlying mechanisms remain elusive. Patients are at a higher risk of recurrence after surgery or drug withdrawal. In this study, to identify a potenti...

    Authors: Junde Zhao, Juntao Wang, Jinxing Liu, Shuling Li, Pengfei Liu and Xiaodan Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:254
  26. Epimedii has long been used as a traditional medicine in Asia for the treatment of various common diseases, including Alzheimer's disease, cancer, erectile dysfunction, and stroke. Studies have reported the am...

    Authors: Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li and De-xi Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:253
  27. Traditional, complementary and alternative medicine (TCAM) is used to treat a broad range of conditions. In low- and middle-income countries (LMICs), TCAM use is particularly common among those with low socio-...

    Authors: Lia M. Palileo-Villanueva, Benjamin Palafox, Arianna Maever L. Amit, Veincent Christian F. Pepito, Fadhlina Ab-Majid, Farnaza Ariffin, Dina Balabanova, Mohamad-Rodi Isa, Nafiza Mat-Nasir, Mazapuspavina My, Alicia Renedo, Maureen L. Seguin, Khalid Yusoff, Antonio L. Dans and Martin Mckee
    Citation: BMC Complementary Medicine and Therapies 2022 22:252
  28. Complementary and Integrative Medicine (CIM) is often taken up by individuals seeking relief from different diseases. This study investigates the prevalence and associated factors of CIM use in patients with C...

    Authors: Mohammad Mahdi Parvizi, Sedigheh Forouhari, Reza Shahriarirad, Sepehr Shahriarirad, Ryan D Bradley and Leila Roosta
    Citation: BMC Complementary Medicine and Therapies 2022 22:251
  29. Akt and mTOR are aberrantly activated in cancers and targeting these proteins are interesting for cancer drug discovery. Napabucasin (NB), a phytochemical compound, has been reported as potential anti-cancer a...

    Authors: Korrakod Petsri, Sunisa Thongsom, Satapat Racha, Supakarn Chamni, Saresa Jindapol, Nantawat Kaekratoke, Hongbin Zou and Pithi Chanvorachote
    Citation: BMC Complementary Medicine and Therapies 2022 22:250
  30. One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes, α-amylase, and α-glucosidases, in the diges...

    Authors: Haimanot Mitiku, Tae Yang Kim, Hanna Kang, Emmanouil Apostolidis, Jung-Yun Lee and Young-In Kwon
    Citation: BMC Complementary Medicine and Therapies 2022 22:249
  31. Complementary medicine therapists such as traditional acupuncturists are a large resource for supporting public health targets to improve health behaviours. Our objectives were to determine the prevalence and ...

    Authors: J. Pinto, K. Bradbury, D. Newell and F. L. Bishop
    Citation: BMC Complementary Medicine and Therapies 2022 22:248
  32. Black salve is a controversial complementary and alternative medicine (CAM) associated with skin toxicity and skin cancer treatment failures. Black salve formulations vary between manufacturers and contain a n...

    Authors: Andrew Croaker, Arie Davis, Anthony Carroll, Lei Liu and Stephen P. Myers
    Citation: BMC Complementary Medicine and Therapies 2022 22:247
  33. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12906-016-1470-9.

    Authors: Vikas Kumar, Prakash Chandra Bhatt, Kalicharan Sharma, Mahfoozur Rahman, Dinesh Kumar Patel, Nikunj Sethi, Atul Kumar, Nikhil Kumar Sachan, Gaurav Kaithwas, F. A. Al-abbasi, Firoz Anwar and Amita Verma
    Citation: BMC Complementary Medicine and Therapies 2022 22:246
  34. Disseminated intravascular coagulation (DIC) is a syndrome characterized by coagulopathy, microthrombus, and multiple organ failure. The complement system in DIC is overactivated, and the functions of compleme...

    Authors: Qi-Yun Zhang, Jing Guo, Lin Xu, Ying Wei, Shu-Ting Zhou, Qing-Yu Lu, Li Guo and Qian-Yun Sun
    Citation: BMC Complementary Medicine and Therapies 2022 22:245
  35. Traditional herbs played a crucial role in the health care of the Hakka people. However, studies to identify these traditional herbs are few. Here we document and assess the potential of these plants for treat...

    Authors: Haibo Hu, Yanfang Yang, Abdallah Aissa, Volkan Tekin, Jialin Li, Sujogya Kumar Panda, Hao Huang and Walter Luyten
    Citation: BMC Complementary Medicine and Therapies 2022 22:244
  36. Cardiovascular diseases cause the death of 17.5 million people every year. Cardiac catheterization is an invasive diagnostic exam that allows treatment followed by the examination and can cause some complicati...

    Authors: Kauanny Vitoria Gurgel dos Santos, Karena Cristina da Silva Leal, Louise Constancia de Melo Alves Silva, Kleyton Santos de Medeiros, Alexsandra Rodrigues Feijão, Maria do Carmo de Oliveira, Daniele Vieira Dantas and Rodrigo Assis Neves Dantas
    Citation: BMC Complementary Medicine and Therapies 2022 22:243
  37. Ecklonia cava is an edible marine brown alga harvested from the ocean that is widely consumed in Asian countries as a health-promoting medicinal food The objective of the present study is to evaluate the anti-as...

    Authors: Kyung Hee Lee, Yeo Jin Jang, Woon Sang Hwang, Ki Sun Kwon, Wha Young Lee, Jeanman Kim, Sung Phil Kim and Mendel Friedman
    Citation: BMC Complementary Medicine and Therapies 2022 22:242
  38. Osteoporosis, a skeletal disease described by impaired bone strength, cause an increased risk of fractures. We aimed in this study to clarify which particular wise combination of probiotics has the most benefi...

    Authors: Ahmad Gholami, Mohammad Hossein Dabbaghmanesh, Younes Ghasemi, Farhad Koohpeyma, Pedram Talezadeh and Nima Montazeri-Najafabady
    Citation: BMC Complementary Medicine and Therapies 2022 22:241
  39. To curb the spread of the first wave of the COVID-19 pandemic, the Swiss government declared a state of health emergency and ordered a legal restriction concerning the opening of healthcare institutions. In th...

    Authors: Angélique Bourqui, Pierre-Yves Rodondi, Emna El May and Julie Dubois
    Citation: BMC Complementary Medicine and Therapies 2022 22:240
  40. Cervical cancer remains one of the significant causes of mortality in women due to the limitations of current treatment strategies and their associated side effects. Investigation of alternative medicine, incl...

    Authors: Saurav Kumar, Vaishali Mulchandani and Jayasri Das Sarma
    Citation: BMC Complementary Medicine and Therapies 2022 22:239
  41. There is paucity of data regarding effects of guided meditation (Yoganidra) on quality of life among patients of chronic kidney disease on maintenance hemodialysis. Our objective was to study effects of guided...

    Authors: Bhalendu S. Vaishnav, Jekishan Jayeshbhai Hirapara and Maulin K. Shah
    Citation: BMC Complementary Medicine and Therapies 2022 22:238
  42. Canadians seeking medical cannabis (MC) may encounter difficulties in finding a healthcare provider (HCP) who authorizes their access to it. Barriers that HCPs face in authorizing MC are unclear. The objective...

    Authors: Yasmina Hachem, Sara J. Abdallah, Sergio Rueda, Jessica L. Wiese, Kamna Mehra, Jennifer Rup, Juthaporn Cowan, Antonio Vigano and Cecilia T. Costiniuk
    Citation: BMC Complementary Medicine and Therapies 2022 22:237
  43. This article has been retracted. Please see the Retraction Notice for more detail: 10.1186/s12906-015-0733-1

    Authors: Cheng Liu, Xia Yuan, Le Tao, Zhuoan Cheng, Xiuqin Dai, Xia Sheng and Dongying Xue
    Citation: BMC Complementary Medicine and Therapies 2022 22:236
  44. Lysiphyllum strychnifolium (Craib) A. Schmitz, a traditional Thai medicinal plant, is mainly composed of polyphenols and flavonoids and exhibits several pharmacological activities, including antioxidant, anticanc...

    Authors: Kunwadee Noonong, Kanta Pranweerapaiboon, Kulathida Chaithirayanon, Kantamat Surayarn, Phicharinee Ditracha, Narin Changklungmoa, Pornanan Kueakhai, Poonsit Hiransai and Kingkan Bunluepuech
    Citation: BMC Complementary Medicine and Therapies 2022 22:235
  45. The COVID-19 pandemic lockdown has had a profound impact on physical and mental well-being throughout the world. Previous studies have revealed that complementary and alternative medicine (CAM) is frequently u...

    Authors: Agnete Egilsdatter Kristoffersen, Miek C. Jong, Johanna Hök Nordberg, Esther T. van der Werf and Trine Stub
    Citation: BMC Complementary Medicine and Therapies 2022 22:234
  46. The plant-based medicinal food (PBMF) is a functional compound extracted from 6 medicinal and edible plants: Coix seed, L. edodes, A. officinalis L., H. cordata, Dandelion, and G. frondosa. Our previous studies h...

    Authors: Lin Tian, Xuxi Chen, Li Cao, Lishi Zhang and Jinyao Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:233
  47. Chronic ultraviolet (UV) exposure is one of the major external factors in skin aging, and repetitive UVB exposure induces extracellular matrix (ECM) damage as well as metabolic disease. Alpinia officinarum Rhizom...

    Authors: Jong Min Jung, Oh Yun Kwon, Jong Kyu Choi and Seung Ho Lee
    Citation: BMC Complementary Medicine and Therapies 2022 22:232
  48. Epilepsy induces behavioral effects and histological changes in the hippocampus. Eugenol, the main component of clove essential oil, has modulatory effects on seizure. We aimed to investigate the effect of int...

    Authors: Fatemeh Parvizi, Soraya Mehrabi, Ayeh Naghizadeh, Mohammad Kamalinejad‬, Sepide Goudarzi and ‬‬‬‬‬‬‬‬‬‬ Maryam Farahmandfar
    Citation: BMC Complementary Medicine and Therapies 2022 22:231