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  1. There is a long history of traditional/complementary medicine (T/CM) use by women during lactation. While it is important to evaluate such use within a scientific paradigm to ensure efficacy and safety, knowle...

    Authors: Tingyun Zheng, Weijie Chen, Hao Hu, Yitao Wang, Joanna E. Harnett and Carolina Oi Lam Ung

    Citation: BMC Complementary Medicine and Therapies 2020 20:122

    Content type: Research article

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  2. This study used a network pharmacology approach to elucidate the molecular mechanism governing the effect of Radix Achyranthis Bidentatae (RAB) on osteoarthritis (OA).

    Authors: Laigen Zhang, Xiaoqing Shi, Zhengquan Huang, Jun Mao, Wei Mei, Liang Ding, Li Zhang, Runlin Xing and Peimin Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:121

    Content type: Research article

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  3. Allergic rhinitis (AR) is a non-infectious immune disease and incidents of the disease has continuously increased in Thailand. Ginger, a Thai herb, is used in food and Thai traditional medicine. This study was...

    Authors: Rodsarin Yamprasert, Waipoj Chanvimalueng, Nichamon Mukkasombut and Arunporn Itharat

    Citation: BMC Complementary Medicine and Therapies 2020 20:119

    Content type: Research article

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  4. Lubiprostone (LBP) is a novel chloride channel opener that has been reported to activate chloride channel protein 2 (ClC-2) and cystic fibrosis transmembrane conductance regulator (CFTR). LBP facilitates fluid...

    Authors: Hiraku Akita, Susumu Yoshie, Takafumi Ishida, Yasuchika Takeishi and Akihiro Hazama

    Citation: BMC Complementary Medicine and Therapies 2020 20:118

    Content type: Research article

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  5. Our previous in vitro study reported that the ethyl acetate fraction (EAF) of Semen sojae germinatum (SSG), the processed sprout of Chinese black soybean, possessed the potent anti-inflammatory and chondroprotect...

    Authors: Jun Wang, Jie Guo, Shulan Li, Mengya Zhang and Bingshu He

    Citation: BMC Complementary Medicine and Therapies 2020 20:117

    Content type: Research article

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  6. Gestational diabetes mellitus (GDM) is one the most common complications of pregnancy. The present work aimed at investigating the effect of ginger on the blood glucose level of GDM women with impaired glucose...

    Authors: Fariba Hajimoosayi, Shahideh Jahanian Sadatmahalleh, Anoshirvan Kazemnejad and Reihane Pirjani

    Citation: BMC Complementary Medicine and Therapies 2020 20:116

    Content type: Research article

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  7. In the present study, the poncirin which is flavonoid-7-o-glycosides (isolated from the Poncirus trifoliata) in nature was evaluated against the Carbon tetra chloride (CCL4)-induced liver injury. The poncirin hav...

    Authors: Hadayat Ullah, Ashrafullah Khan, Muhammad Waleed Baig, Naseem Ullah, Naveed Ahmed, Muhammad Khalid Tipu, Hussain Ali and Salman Khan

    Citation: BMC Complementary Medicine and Therapies 2020 20:115

    Content type: Research article

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  8. Hancornia speciosa is usually used in Brazilian folk medicine to treat diabetes. The hypothesis of the present study is that this medicinal plant exerts beneficial effects on hyperglycemia, preventing diabetic co...

    Authors: Leila S. Neto, Rafaianne Q. Moraes-Souza, Thaigra S. Soares, Marcelo S. Pinheiro, Thaís Leal-Silva, Juliana C. Hoffmann, Madileine F. Américo, Kleber E. Campos, Débora C. Damasceno and Gustavo T. Volpato

    Citation: BMC Complementary Medicine and Therapies 2020 20:114

    Content type: Research article

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  9. Shenmai injection (SMI) has been used in the treatment of cardiovascular disease (CVD), such as heart failure, myocardial ischemia and coronary heart disease. It has been found to have efficacy on doxorubicin ...

    Authors: Lin Li, Dongli Yang, Jinghao Li, Lu Niu, Ye Chen, Xin Zhao, Patrick Kwabena Oduro, Chun Wei, Zongpei Xu, Qilong Wang and Yuhong Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:112

    Content type: Research article

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  10. Many German general practitioners (GPs) use complementary and alternative medicine (CAM) in their daily work although most CAM procedures are controversial from an academic point of view.

    Authors: Agnes Ostermaier, Niklas Barth and Klaus Linde

    Citation: BMC Complementary Medicine and Therapies 2020 20:111

    Content type: Research article

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  11. Ovarian cancer is the leading cause of mortality among malignant gynecological tumors. Surgical resection and chemotherapy with intravenous platinum/taxanes drugs are the treatments of choice, with little effe...

    Authors: Luis Varela-Rodríguez, Blanca Sánchez-Ramírez, Verónica Ivonne Hernández-Ramírez, Hugo Varela-Rodríguez, Rodrigo Daniel Castellanos-Mijangos, Carmen González-Horta, Bibiana Chávez-Munguía and Patricia Talamás-Rohana

    Citation: BMC Complementary Medicine and Therapies 2020 20:110

    Content type: Research article

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  12. Ligularia fischeri (Ledeb) Turcz (LFT) is a well-known expectorant and active anti-inflammatory agent in Chinese traditional medicine. LFT’s expectorant effect is closely related to its anti-inflammatory effects....

    Authors: Xulong Huang, Yuan Gao, Feng Xu, Dongsheng Fan, Yuqing Liang, Xiangpei Wang and Hongmei Wu

    Citation: BMC Complementary Medicine and Therapies 2020 20:109

    Content type: Research article

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  13. While the use of complementary and alternative medicine (CAM) has become increasingly popular in western societies, we do not understand why CAM use is more frequent in some countries than in others. The aim o...

    Authors: Erlend L. Fjær, Erling R. Landet, Courtney L. McNamara and Terje A. Eikemo

    Citation: BMC Complementary Medicine and Therapies 2020 20:108

    Content type: Research article

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  14. The incidence of insulin resistance (IR) has rapidly increased worldwide over the last 20 years, no perfect solution has yet been identified. Finding new therapeutic drugs will help improve this situation. As ...

    Authors: Wen Gu, Min Yang, Qian Bi, Lin-Xi Zeng, Xi Wang, Jin-Cai Dong, Feng-Jiao Li, Xing-Xin Yang, Jing-Ping Li and Jie Yu

    Citation: BMC Complementary Medicine and Therapies 2020 20:107

    Content type: Research article

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  15. Combretum molle R.B/G. Don (Combretaceae) is a graceful deciduous shrub, distributed especially in tropical Africa and used in traditional medicine in the treatment of malaria, diabetes, and bacterial, liver and ...

    Authors: David Miaffo, Sylvie Léa Wansi, Fidèle Ntchapda and Albert Kamanyi

    Citation: BMC Complementary Medicine and Therapies 2020 20:106

    Content type: Research article

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  16. Cissus quadrangularis Linn. (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients in CQ. It is still unclear which compounds are the active i...

    Authors: Jetsada Ruangsuriya, Suporn Charumanee, Supat Jiranusornkul, Panee Sirisa-ard, Busaban Sirithunyalug, Jakkapan Sirithunyalug, Thanawat Pattananandecha and Chalermpong Saenjum

    Citation: BMC Complementary Medicine and Therapies 2020 20:105

    Content type: Research article

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  17. Peri-implant inflammation resulting from the presence of Candida biofilms may compromise the longevity of implant-supported dentures. This study evaluated the inhibitory effect of Brazilian red propolis on mono-s...

    Authors: Loyse Martorano-Fernandes, Yuri Wanderley Cavalcanti and Leopoldina de Fátima Dantas de Almeida

    Citation: BMC Complementary Medicine and Therapies 2020 20:104

    Content type: Research article

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  18. Lamiaceae family is one of the most diverse and common plant families in terms of ethnomedicine due to their potential therapeutic effects. The aim of this study is to investigate the correlation between the c...

    Authors: Sarra Moumni, Ameur Elaissi, Amine Trabelsi, Abderrahmen Merghni, Imed Chraief, Brahim Jelassi, Rachid Chemli and Salima Ferchichi

    Citation: BMC Complementary Medicine and Therapies 2020 20:103

    Content type: Research article

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  19. Panch phoron is a mixture of five spices containing an equal proportion of Foeniculum vulgare (fennel), Trigonella foenum-graecum Linn (fenugreek), Nigella sativa (black cumin), Cuminum cyminum (cumin) and Brassi...

    Authors: Zarin Tasnim Gias, Fatima Afsana, Polak Debnath, M. Shadidul Alam, Tania Naz Ena, Md Hemayet Hossain, Preeti Jain and Hasan Mahmud Reza

    Citation: BMC Complementary Medicine and Therapies 2020 20:102

    Content type: Research article

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  20. Particulate matter (PM) can cause various negative acute and chronic diseases of the respiratory system, including the upper airways. Curcumin has been reported to have anti-inflammatory and anti-oxidative eff...

    Authors: Ji-Sun Kim, Jeong-Min Oh, Hyunsu Choi, Sung Won Kim, Soo Whan Kim, Byung Guk Kim, Jin Hee Cho, Joohyung Lee and Dong Chang Lee

    Citation: BMC Complementary Medicine and Therapies 2020 20:101

    Content type: Research article

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  21. Few studies have evaluated the association between the risk of coronary artery disease (CAD) and the use of Chinese herbal products (CHP) in patients with rheumatoid arthritis (RA). This study investigated the...

    Authors: Han-Hua Yu, Nai-Huan Hsiung, Jen-Huai Chiang and Hsuan-Shu Shen

    Citation: BMC Complementary Medicine and Therapies 2020 20:100

    Content type: Research article

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  22. Staphylococcus aureus is the most dominant human pathogen, responsible for a variety of chronic and severe infections. There is mounting evidence that persisters are associated with treatment failure and relapse ...

    Authors: Shuzhen Xiao, Peng Cui, Wanliang Shi and Ying Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:99

    Content type: Research article

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  23. The Rumex acetosa has been used in medicinal treatment, food technology and phytotherapeutics in Eastern Asia and many other countries. However, its effect on cardiovascular system and antiplatelet activity remai...

    Authors: Dahye Jeong, Muhammad Irfan, Dong-Ha Lee, Seung-Bok Hong, Jae-Wook Oh and Man Hee Rhee

    Citation: BMC Complementary Medicine and Therapies 2020 20:98

    Content type: Research article

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  24. Frankincense and myrrh are used as traditional anti-inflammatory and analgesic medicines in China. It has been reported that frankincense and myrrh have significant anti-tumor activities. The present study was...

    Authors: Rumeng Gao, Xiaodong Miao, Chengjing Sun, Shulan Su, Yue Zhu, Dawei Qian, Zhen Ouyang and Jinao Duan

    Citation: BMC Complementary Medicine and Therapies 2020 20:96

    Content type: Research article

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  25. Ovarian cancer therapy generally involves systemic chemotherapy with anticancer drugs; however, chemotherapy with a platinum-based drug has often been shown to cause adverse reactions and drug resistance in ov...

    Authors: Jae Ryul Bae, Wook Ha Park, Dong Hoon Suh, Jae Hong No, Yong Beom Kim and Kidong Kim

    Citation: BMC Complementary Medicine and Therapies 2020 20:94

    Content type: Research article

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  26. Previous research has revealed high rates of traditional medicine usage in Nigeria. Reports of widespread contamination of herbal medicine products and higher rates of noncompliance with Western medications am...

    Authors: Suellen Li, Stella Odedina, Imaria Agwai, Oladosu Ojengbede, Dezheng Huo and Olufunmilayo I. Olopade

    Citation: BMC Complementary Medicine and Therapies 2020 20:93

    Content type: Research article

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  27. Acinetobacter baumannii is an opportunistic pathogen that causes nosocomial infections especially in patients in intensive care units (ICUs). Accordingly, the aim of our study was to detection of adeABC efllux pu...

    Authors: Hassan Mahmoudi, Leili Shokoohizadeh, Nayreh Zare Fahim, Ali Mohamadi Bardebari, Shirin Moradkhani and Mohammad Yousef Alikhani

    Citation: BMC Complementary Medicine and Therapies 2020 20:92

    Content type: Research article

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  28. Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growi...

    Authors: Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew, Zhi-Yu Qiu, Xin-Rong Cheryl Tsai, Sin-Yi How, Keng-Yan Caleb Yip, Chay-Hoon Tan and Hwee-Ling Koh

    Citation: BMC Complementary Medicine and Therapies 2020 20:91

    Content type: Research article

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  29. Parents often choose Complementary and Alternative Medicine (CAM) as a supportive agent with the aim to reduce cancer treatment-related symptoms in their children. Therefore, it is necessary to understand pare...

    Authors: Trine Stub, Agnete E. Kristoffersen, Grete Overvåg and Miek C. Jong

    Citation: BMC Complementary Medicine and Therapies 2020 20:90

    Content type: Research article

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  30. Hydrolates, complex mixtures containing traces of essential oils (EOs), are inexpensive, easy to make and less toxic than their corresponding EOs. The antibacterial and antifungal activity of the hydrolate of Cor...

    Authors: Andreana Marino, Antonia Nostro, Narcisa Mandras, Janira Roana, Giovanna Ginestra, Natalizia Miceli, Maria Fernanda Taviano, Fabrizio Gelmini, Giangiacomo Beretta and Vivian Tullio

    Citation: BMC Complementary Medicine and Therapies 2020 20:89

    Content type: Research article

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  31. Sedum sarmentosum is traditionally used to treat various inflammatory diseases in China. It has protective effects against acute liver injury, but the exact mechanism of such effects remains unclear. This study i...

    Authors: Li Hao, Ming-wei Liu, Song-tao Gu, Xue Huang, Hong Deng and Xu Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:88

    Content type: Research article

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  32. The antiprotozoal and antioxidant activities of Viola tricolor and Laurus nobilis have been reported recently. Thus, the existing study pursued to assess the growth inhibition effect of methanolic extract of V. t...

    Authors: Gaber El-Saber Batiha, Amany Magdy Beshbishy, Luay Alkazmi, Oluyomi Stephen Adeyemi, Eman Nadwa, Eman Rashwan, Amany El-Mleeh and Ikuo Igarashi

    Citation: BMC Complementary Medicine and Therapies 2020 20:87

    Content type: Research article

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  33. Myrtus communis is a typical plant of Mediterranean area. The different parts of this plant such as berries, branches, and leaves have been used worldwide as a traditional/folk medicine for the treatment of vario...

    Authors: Mushtaq A. Mir, Nasreena Bashir, Abdulkhaleg Alfaify and Mohammed D. Y. Oteef

    Citation: BMC Complementary Medicine and Therapies 2020 20:86

    Content type: Research article

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  34. Honey is a versatile and complex substance consisting of bioactive chemicals which vary according to many bee and environmental factors. The aim of this study was to assess the physical and antimicrobial prope...

    Authors: Elijah Brown, Michel O’Brien, Karla Georges and Sharianne Suepaul

    Citation: BMC Complementary Medicine and Therapies 2020 20:85

    Content type: Research article

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  35. Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are u...

    Authors: Mitsuki Tabata, Masanobu Tsubaki, Tomoya Takeda, Keisuke Tateishi, Katsumasa Tsurushima, Motohiro Imano, Takao Satou, Toshihiko Ishizaka and Shozo Nishida

    Citation: BMC Complementary Medicine and Therapies 2020 20:84

    Content type: Research article

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  36. Recent studies pointed up that curcumin produces an anti-nociceptive effect in inflammatory and neuropathic pain. However, the possible mechanisms of action that underline the anti-allodynic effect induced by ...

    Authors: Tracy Pastrana-Quintos, Giovanna Salgado-Moreno, Julia Pérez-Ramos, Arrigo Coen and Beatriz Godínez-Chaparro

    Citation: BMC Complementary Medicine and Therapies 2020 20:83

    Content type: Research article

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  37. Daily “eye exercises,” massaging of periocular acupuncture pressure points, have been part of China’s national vision care policy in schools for some 50 years. However, the effect of eye exercises on myopia pr...

    Authors: Huan Wang, Yiwei Qian, Nathan Congdon, Matthew Boswell, Scott Rozelle and Xiaochen Ma

    Citation: BMC Complementary Medicine and Therapies 2020 20:82

    Content type: Research article

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  38. Skin-related diseases affect every individual irrespective of age, gender or social status. Since time immemorial, humans have explored natural resources from their environment for the maintenance of the skin....

    Authors: Mamokete Venolia Setshego, Adeyemi Oladapo Aremu, Obakeng Mooki and Wilfred Otang-Mbeng

    Citation: BMC Complementary Medicine and Therapies 2020 20:81

    Content type: Research article

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  39. The health benefits of botanicals is linked to their phytochemicals that often exert pleiotropic effects via targeting multiple molecular signaling pathways such as the peroxisome proliferator-activated recept...

    Authors: Mebrahtom Gebrelibanos Hiben, Laura de Haan, Bert Spenkelink, Sebastiaan Wesseling, Jacques Vervoort and Ivonne M. C. M. Rietjens

    Citation: BMC Complementary Medicine and Therapies 2020 20:80

    Content type: Research article

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  40. In the context of searching for potent, safe, natural antimicrobial agents to combate the global antimicrobial resistance (AMR) phenomenon, the current study evaluates for the first time ever, the broad-spectr...

    Authors: Huda Naeim, Amr El-Hawiet, Raoufa A. Abdel Rahman, Ahmed Hussein, Maha A. El Demellawy and Amira M. Embaby

    Citation: BMC Complementary Medicine and Therapies 2020 20:79

    Content type: Research article

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  41. The active components of Dracocephalum moldavica L. (TFDM) can inhibit myocardial ischemia by inhibiting oxidative stress. However, the effects of TFDM on astrocytes have not been investigated in vitro. The curre...

    Authors: Rui-Fang Zheng, Yan-Wen Du, Cheng Zeng, Hui-Fang Wang, Jian-Guo Xing and Ming Xu

    Citation: BMC Complementary Medicine and Therapies 2020 20:78

    Content type: Research article

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  42. Germacrone is an anti-inflammatory ingredient in the Chinese medicine zedoary turmeric. The purpose of this study was to explore the protective mechanism of germacrone against PC12 cells injury caused by oxyge...

    Authors: Jianxing Zhang, Li Yuan, Sujie Wang, Jiang Liu, Huiqin Bi, Guojuan Chen, Jingjing Li and Lili Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:77

    Content type: Research article

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  43. The embryos of Nelumbo nucifera Gaertn seeds, lianzixin, are used in China as food and traditional herbal medicine. Principal therapeutic indications are insomnia, anxiety and pyrexia. Caffeine is a psychostimula...

    Authors: Jingjing Chen, Mimi Tang, Manhua Liu, Yueping Jiang, Bin Liu and Shao Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:76

    Content type: Research article

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  44. Various extracts of Hovenia dulcis have been commonly used in Asia for cases of alcohol-related disorders. Fermentation is reported to enhance the level and biological activities of various bio-constituents of pl...

    Authors: Na-Hye Park, Seung-Jin Lee, Abraham Fikru Mechesso, Naila Boby, Quah Yixian, Woong-Kyu Yoon, Sam-Pin Lee, Jong-Suk Lee and Seung-Chun Park

    Citation: BMC Complementary Medicine and Therapies 2020 20:75

    Content type: Research article

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  45. Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, a...

    Authors: Mustafa T. Ardah, Simona S. Ghanem, Sara A. Abdulla, Guohua Lv, Mohamed M. Emara, Katerina E. Paleologou, Nishant N. Vaikath, Jia-Hong Lu, Min Li, Konstantinos Vekrellis, David Eliezer and Omar M. A. El-Agnaf

    Citation: BMC Complementary Medicine and Therapies 2020 20:73

    Content type: Research article

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  46. Cranberry has been studied as a potential anticancer agent as it is capable of inducing apoptosis within cancer cells. The aim of this study was to better define the mechanism by which cranberry triggers apopt...

    Authors: Rasha A. Mansouri and Susan S. Percival

    Citation: BMC Complementary Medicine and Therapies 2020 20:71

    Content type: Research article

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  47. Post-traumatic stress disorder (PTSD) is an extreme mood disorder that occurs after experiencing extreme stress, and patients with this disorder are known to accompany with symptoms of depression, anxiety, and...

    Authors: Bombi Lee, Gwang Muk Choi and Bongjun Sur

    Citation: BMC Complementary Medicine and Therapies 2020 20:70

    Content type: Research article

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