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  1. A Saururus chinensis Baill (SC) has been used by Native Americans, early colonists and practitioners of Korean traditional medicine for treating several diseases including cancer, rheumatoid arthritis and edema. ...

    Authors: Byung-Wook Kim, Sushruta Koppula, Shin-Young Park, Jin-Woo Hwang, Pyo-Jam Park, Ji-Hong Lim and Dong-Kug Choi
    Citation: BMC Complementary and Alternative Medicine 2014 14:502
    Content type: Research article Published on:

  2. Moxibustion is one of the most commonly used therapies in acupuncture practice, and is demonstrated to be beneficial for patients with diarrhea from irritable bowel syndrome (D-IBS). But its mechanism remains ...

    Authors: Yi Zhu, Zhiyuan Wu, Xiaopeng Ma, Huirong Liu, Chunhui Bao, Ling Yang, Yunhua Cui, Cili Zhou, Xiaomei Wang, Yuemin Wang, Zhongwei Zhang, Huan Zhang, Haipeng Jia and Huangan Wu
    Citation: BMC Complementary and Alternative Medicine 2014 14:500
    Content type: Research article Published on:

  3. Bacteria within a biofilm are phenotypically more resistant to antibiotics, desiccation, and the host immune system, making it an important virulence factor for many microbes. Cranberry juice has long been use...

    Authors: Robert K Ulrey, Stephanie M Barksdale, Weidong Zhou and Monique L van Hoek
    Citation: BMC Complementary and Alternative Medicine 2014 14:499
    Content type: Research article Published on:

  4. Paclitaxel induced fatigue still remains underrecognized and undertreated, partly because of limited understanding of its pathophysiology and lack of effective treatments. This study is aim to evaluate the ant...

    Authors: Mingzi Ouyang, Yanyan Liu, Wei Tan, Ya Xiao, Keqiang Yu, Xiaomin Sun, Ying Huang, JingRu Cheng, Ren Luo and Xiaoshan Zhao
    Citation: BMC Complementary and Alternative Medicine 2014 14:497
    Content type: Research article Published on:

  5. Many studies show an effectiveness of hypnotic analgesia. It has been discussed whether the analgesic effect is mainly caused by the relaxation that is concomitant to hypnosis. This study was designed to evalu...

    Authors: Sybille Kramer, Rolf Zims, Michael Simang, Linda Rüger and Dominik Irnich
    Citation: BMC Complementary and Alternative Medicine 2014 14:496
    Content type: Research article Published on:

  6. The foraging choices of honey bees are influenced by many factors, such as floral aroma. The composition of volatile compounds influences the bioactivity of the aromatic plants and honey produced from them. In...

    Authors: Hanaa Yamani, Nitin Mantri, Paul D Morrison and Edwin Pang
    Citation: BMC Complementary and Alternative Medicine 2014 14:495
    Content type: Research article Published on:

  7. Acetaminophen (APAP)-induced toxicity is a predominant cause of acute hepatic and renal failure. In both humans and rodents toxicity begins with a reactive metabolite that binds to proteins. This leads to mito...

    Authors: Yahya M Naguib, Rania M Azmy, Rehab M Samaka and Mohamed F Salem
    Citation: BMC Complementary and Alternative Medicine 2014 14:494
    Content type: Research article Published on:

  8. Radix Salviae miltiorrhizae is a herb frequently used within traditional Chinese medicine for the treatment of cardiovascular- and trauma-related diseases. Danshen is the dried root of Salviae miltiorrhizae, fro...

    Authors: Xufeng He and Qiang Shen
    Citation: BMC Complementary and Alternative Medicine 2014 14:493
    Content type: Research article Published on:

  9. The development of resistant to current antimalarial drugs is a major challenge in achieving malaria elimination status in many countries. Therefore there is a need for new antimalarial drugs. Medicinal plants...

    Authors: Mohd Ridzuan Mohd Abd Razak, Adlin Afzan, Rosnani Ali, Nur Fasihah Amir Jalaluddin, Mohd Isa Wasiman, Siti Habsah Shiekh Zahari, Noor Rain Abdullah and Zakiah Ismail
    Citation: BMC Complementary and Alternative Medicine 2014 14:492
    Content type: Research article Published on:

  10. Wedelia chinensis is traditionally used as a hepatoprotective herb in Taiwan. The aim of this study was to evaluate the neuroprotective potential of W. chinensis.

    Authors: Wea-Lung Lin, Shao-Ming Wang, Ying-Jui Ho, Hsing-Chun Kuo, Yean-Jang Lee and Tsui-Hwa Tseng
    Citation: BMC Complementary and Alternative Medicine 2014 14:491
    Content type: Research article Published on:

  11. The four-herb Chinese medicine PHY906(KD018) has been shown to both enhance the in vivo antitumor activity of irinotecan (CPT-11) against colon cancer tumor allografts and alleviate intestinal toxicity caused by ...

    Authors: Wing Lam, Zaoli Jiang, Fulan Guan, Rong Hu, Shwu-Huey Liu, Edward Chu and Yung-Chi Cheng
    Citation: BMC Complementary and Alternative Medicine 2014 14:490
    Content type: Research article Published on:

  12. The search for alternative therapies for oral candidiasis is a necessity and the use of medicinal plants seems to be one of the promising solutions. The objective of this study was to evaluate the in vitro and in...

    Authors: Vanessa Maria de Campos Rasteiro, Anna Carolina Borges Pereira da Costa, Cássia Fernandes Araújo, Patrícia Pimentel de Barros, Rodnei Dennis Rossoni, Ana Lia Anbinder, Antonio Olavo Cardoso Jorge and Juliana Campos Junqueira
    Citation: BMC Complementary and Alternative Medicine 2014 14:489
    Content type: Research article Published on:

  13. Complementary therapies are widely used among cancer patients. Kuan-Sin-Yin (KSY) decoction, a popular qi-promoting herbal medicine, was constituted with several herbs known to exhibit immunomodulating or anti...

    Authors: Tsai-Feng Li, Ching-Cheng Lin, Hui-ping Tsai, Chung-Hua Hsu and Shu-Ling Fu
    Citation: BMC Complementary and Alternative Medicine 2014 14:488
    Content type: Research article Published on:

  14. Recently, Abeliophyllum distichum Nakai (A. distichum) has been reported to exert the inhibitory effect on angiotensin converting enzyme. However, no specific pharmacological effects from A. distichum have been d...

    Authors: Gwang Hun Park, Jae Ho Park, Hyun Ji Eo, Hun Min Song, So Hee Woo, Mi Kyoung Kim, Jin Wook Lee, Man Hyo Lee, Jeong Rak Lee, Jin Suk Koo and Jin Boo Jeong
    Citation: BMC Complementary and Alternative Medicine 2014 14:487
    Content type: Research article Published on:

  15. Pain and anxiety occurring from cardiovascular disease are associated with long-term health risks. Integrative medicine (IM) therapies reduce pain and anxiety in small samples of hospitalized cardiovascular pa...

    Authors: Jill R Johnson, Daniel J Crespin, Kristen H Griffin, Michael D Finch, Rachael L Rivard, Courtney J Baechler and Jeffery A Dusek
    Citation: BMC Complementary and Alternative Medicine 2014 14:486
    Content type: Research article Published on:

  16. The fruit of Rosa moschata has traditionally been used for the treatment of abdominal spasm and diarrhoea. Therefore, the aim of this study was to investigate mechanism(s) responsible for its medicinal use in gut...

    Authors: Niaz Ali, Hina Alam, Aslam Khan, Ghayour Ahmed, Wadood Ali Shah, Muhammad Nabi and Muhammad Junaid
    Citation: BMC Complementary and Alternative Medicine 2014 14:485
    Content type: Research article Published on:

  17. Isoflavones are naturally occurring plant chemicals belonging to the “phytoestrogen” class. The aim of the present study was to examine the effects of isoflavones obtained from Cordyceps sinensis (CSIF) on develo...

    Authors: Da-wei Zhang, Zhen-lin Wang, Wei Qi and Guang-yue Zhao
    Citation: BMC Complementary and Alternative Medicine 2014 14:484
    Content type: Research article Published on:

  18. Huachansu injection (HCS) is a water-soluble preparation made from Bufo gargarizans’s skin, which has been widely used in clinics for tumor therapy in China. Though the anti-cancer activity of HCS has been ver...

    Authors: Jian-Hua Yin, Xiao-Yan Zhu, Wei-Dong Shi and Lu-Ming Liu
    Citation: BMC Complementary and Alternative Medicine 2014 14:483
    Content type: Research article Published on:

  19. The physiological effects of the non-anthocyanin fraction (NAF) in a black soybean seed coat extract on Aβ-induced oxidative stress were investigated to confirm neuroprotection. In addition, we examined the pr...

    Authors: Ji Hee Jeong, Hyeon Ju Kim, Seon Kyeong Park, Dong Eun Jin, O-Jun Kwon, Hyun-Jin Kim and Ho Jin Heo
    Citation: BMC Complementary and Alternative Medicine 2014 14:482
    Content type: Research article Published on:

  20. Destructive erosion of bone or osteolysis is a major complication of inflammatory conditions such as rheumatoid arthritis (RA), periodontal disease, and periprosthetic osteolysis. Natural plant-derived product...

    Authors: Lingbo Kong, Qinpeng Zhao, Xiaodong Wang, Jinyu Zhu, Dingjun Hao and Chongfei Yang
    Citation: BMC Complementary and Alternative Medicine 2014 14:481
    Content type: Research article Published on:

  21. The young shoots of Rubus idaeus are traditionally used as a herbal remedy in common cold, fever and flu-like infections yet there is no research concerning this plant material. The aim of the study was to evalua...

    Authors: Mirosława Krauze-Baranowska, Daniel Głód, Marta Kula, Magdalena Majdan, Rafał Hałasa, Adam Matkowski, Weronika Kozłowska and Anna Kawiak
    Citation: BMC Complementary and Alternative Medicine 2014 14:480
    Content type: Research article Published on:

  22. Traditionally, Operculina turpethum has been used in a wide range of ailments such as, gastrointestinal disturbances and asthma. It is found in China, South Asia, Pacific Islands, and Australia. This study was ai...

    Authors: Huma Shareef, Ghazala H Rizwani, Safur R Mandukhail, Naoharu Watanabe and Anwar H Gilani
    Citation: BMC Complementary and Alternative Medicine 2014 14:479
    Content type: Research article Published on:

  23. Dental caries is the most prevalent oral disease in several Asian and Latin American countries. It is an infectious disease and different types of bacteria are involved in the process. Synthetic antimicrobials...

    Authors: Juçara R Franca, Mariana P De Luca, Tatiana G Ribeiro, Rachel O Castilho, Allyson N Moreira, Vagner R Santos and André AG Faraco
    Citation: BMC Complementary and Alternative Medicine 2014 14:478
    Content type: Research article Published on:

  24. Platelet-derived growth factor–BB (PDGF-BB) is highly expressed in the renal tissues of patients with diabetic nephropathy, and it plays an important role in the initiation and progression of diabetic nephropa...

    Authors: Eunjin Sohn, Junghyun Kim, Chan-Sik Kim, Kyuhyung Jo, Yun Mi Lee and Jin Sook Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:477
    Content type: Research article Published on:

  25. In this study, we investigate the effects of valerian root extracts (VE) on physical and psychological stress responses by utilizing a communication box.

    Authors: Hyo Young Jung, Dae Young Yoo, Woosuk Kim, Sung Min Nam, Jong Whi Kim, Jung Hoon Choi, Youn-Gil Kwak, Yeo Sung Yoon and In Koo Hwang
    Citation: BMC Complementary and Alternative Medicine 2014 14:476
    Content type: Research article Published on:

  26. Humans are exposed to toxins which accumulate in the body, and are detoxified primarily in the liver. Studies have shown that cruciferous vegetables (such as radishes) may be beneficial to health by aiding det...

    Authors: Malkanthi Evans, Elaine Paterson and David M Barnes
    Citation: BMC Complementary and Alternative Medicine 2014 14:475
    Content type: Research article Published on:

  27. Leonurus heterophyllus sweet has been suggested to have cardioprotective effects against heart diseases, including ischemic diseases and ventricular remodeling. However, the active ingredients of the herb and th...

    Authors: Chen Zhang, Xiao-Li Shan, Yue-Ling Liao, Pei Zhao, Wei Guo, Hong-Chang Wei and Rong Lu
    Citation: BMC Complementary and Alternative Medicine 2014 14:474
    Content type: Research article Published on:

  28. Despite a high prevalence of herbal and dietary supplement use (HDS) in pre-dialysis patients, the reasons are unknown as to why they decide to use HDS. Objectives of the cross-sectional and qualitative studie...

    Authors: Mayuree Tangkiatkumjai, Helen Boardman, Kearkiat Praditpornsilpa and Dawn-Marie Walker
    Citation: BMC Complementary and Alternative Medicine 2014 14:473
    Content type: Research article Published on:

  29. Polycystic ovary syndrome (PCOS) is a complex reproductive endocrinopathy affecting up to 20% of reproductive aged women. Whilst there are effective pharmaceutical treatment options, women with PCOS have expre...

    Authors: Susan Arentz, Caroline Anne Smith, Jason Anthony Abbott and Alan Bensoussan
    Citation: BMC Complementary and Alternative Medicine 2014 14:472
    Content type: Research article Published on:

  30. Oxaliplatin, an important chemotherapy drug for advanced colorectal cancer, often induces peripheral neuropathy, especially cold allodynia. Our previous study showed that bee venom acupuncture (BVA), which has...

    Authors: Ji-Hye Lee, Dong Xing Li, Heera Yoon, Donghyun Go, Fu Shi Quan, Byung-Il Min and Sun Kwang Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:471
    Content type: Research article Published on:

  31. Altered plasma lipids, oxidative stress, and inflammation have been involved in the pathogenesis of cardiovascular disease. Fish oil has shown inconclusive effects on plasma lipids and oxidative stress. Spirul...

    Authors: Miriam Adoyo Muga and Jane C-J Chao
    Citation: BMC Complementary and Alternative Medicine 2014 14:470
    Content type: Research article Published on:

  32. Tocotrienols, especially the gamma isomer was discovered to possess cytotoxic effects associated with the induction of apoptosis in numerous cancers. Individual tocotrienol isomers are believed to induce dissi...

    Authors: Su-Wen Lim, Hwei-San Loh, Kang-Nee Ting, Tracey D Bradshaw and Nazariah A Zeenathul
    Citation: BMC Complementary and Alternative Medicine 2014 14:469
    Content type: Research article Published on:

  33. Edible birds’ nest (EBN) is reported to be antioxidant-rich. However, the fate of its antioxidants after oral consumption is not yet reported. To explore this, we hypothesized that EBN antioxidants are release...

    Authors: Zhang Yida, Mustapha Umar Imam and Maznah Ismail
    Citation: BMC Complementary and Alternative Medicine 2014 14:468
    Content type: Research article Published on:

  34. Apoptosis is often the end result of oxidative damage to neurons. Due to shared pathways between oxidative stress, apoptosis and antioxidant defence systems, an oxidative insult could end up causing cellular a...

    Authors: Norsharina Ismail, Maznah Ismail, Mustapha Umar Imam, Nur Hanisah Azmi, Siti Farhana Fathy, Jhi Biau Foo and Muhammad Firdaus Abu Bakar
    Citation: BMC Complementary and Alternative Medicine 2014 14:467
    Content type: Research article Published on:

  35. Studies suggest an important role of autophagy as a target for cancer therapy. We constructed a "disease-gene-drug" network using the modular approach of bioinformatics and screened herbal monomers demonstrati...

    Authors: Chenjun Hao, Zhengpeng Yang, Bo Gao, Ming Lu, Xianzhi Meng, Xin Qiao, Dongbo Xue and Weihui Zhang
    Citation: BMC Complementary and Alternative Medicine 2014 14:466
    Content type: Research article Published on:

  36. Polygonum hydropiper L decoctions are traditionally used in the treatment of various ailments including inflammation, dyspepsia, diarrhea, menorrhagia, hemorrhoids, helminthiasis and CNS disorders. Present study...

    Authors: Muhammad Ayaz, Muhammad Junaid, Fazal Subhan, Farhat Ullah, Abdul Sadiq, Sajjad Ahmad, Muhammad Imran, Zul Kamal, Sajid Hussain and Syed Majid Shah
    Citation: BMC Complementary and Alternative Medicine 2014 14:465
    Content type: Research article Published on:

  37. Vanda tessellata (Orchidaceae) has been used in different sorts of ailments such as inflammations, rheumatism, dysentery, bronchitis, dyspepsia and fever in folk medicine. In this study we evaluated the antinoci...

    Authors: M Anisuzzaman Chowdhury, M Masudur Rahman, Mohammed Riaz Hasan Chowdhury, M Josim Uddin, Mohammed Abu Sayeed and M Aslam Hossain
    Citation: BMC Complementary and Alternative Medicine 2014 14:464
    Content type: Research article Published on:

  38. Self-reported use of Complementary and Alternative Medicine (CAM) varies widely from 10% to 75% in the general populations worldwide. When limited to use of a CAM provider 2% to 49% reported use is found. CAM ...

    Authors: Agnete E Kristoffersen, Trine Stub, Anita Salamonsen, Frauke Musial and Katarina Hamberg
    Citation: BMC Complementary and Alternative Medicine 2014 14:463
    Content type: Research article Published on:

  39. Malaria is one of the most important infectious diseases in the World. The choice for the treatment is highly limited, and several of these may eventually be lost or compromised due to drug resistance. The use...

    Authors: Wote Amelo, Pushpa Nagpal and Eyassu Makonnen
    Citation: BMC Complementary and Alternative Medicine 2014 14:462
    Content type: Research article Published on:

  41. The leaf of Zehneria scabra is traditionally used for the management of diarrhea in Ethiopia. Its use, however, has not been scientifically validated for safety and efficacy. The aim of this study was to investig...

    Authors: Wondmagegn Tamiru Tadesse, Abebe Ejigu Hailu, Abyot Endale Gurmu and Abraham Fikru Mechesso
    Citation: BMC Complementary and Alternative Medicine 2014 14:460
    Content type: Research article Published on:

  42. Necroptosis is an important mode of cell death, which is due to oxidant stress accumulation. Our previous study indicated that oxidant stresses could be reduced by Timosaponin B-II (TBII), a kind of Chinese herb

    Authors: San-Hong Jiang, Lei Shang, Li-Xiang Xue, Wei Ding, Shuang Chen, Ruo-Fei Ma, Ju-Fang Huang and Kun Xiong
    Citation: BMC Complementary and Alternative Medicine 2014 14:459
    Content type: Research article Published on:

  43. The safety of Deltamethrin (DM) has been raised as a point of concern. The current investigation was envisaged to explore the responsiveness of oxidative stress parameters, DNA fragmentation and expression lev...

    Authors: Mona K Galal, Abdel Azim A Khalaf, Hanan A Ogaly and Marwa A Ibrahim
    Citation: BMC Complementary and Alternative Medicine 2014 14:458
    Content type: Research article Published on:

  44. An overdose of paracetamol is a frequent reason for liver and renal toxicity and possible death and curcumin has hepatoprotective properties against liver damage. The exact mechanism of such protection is not ...

    Authors: Mohamed Mohamed Soliman, Mohamed Abdo Nassan and Tamer Ahmed Ismail
    Citation: BMC Complementary and Alternative Medicine 2014 14:457
    Content type: Research article Published on:

  45. Strychnos spinosa Lam. is a deciduous tree used in traditional medicine to treat infectious diseases. This study is designed to determine the antimicrobial, antioxidant and cytotoxic activities of extracts and f...

    Authors: Adamu Imam Isa, Maurice Ducret Awouafack, Jean Paul Dzoyem, Mohammed Aliyu, Rabiu AbduSsalam Magaji, Joseph Olusegun Ayo and Jacobus Nicolaas Eloff
    Citation: BMC Complementary and Alternative Medicine 2014 14:456
    Content type: Research article Published on:

  46. Panax ginseng is a famous traditional medicine in Korea for its beneficial effect on obesity, cardiac and liver associated diseases. The aim of this study was to investigate the metabolite in Panax ginseng (P....

    Authors: Seung Ok Yang, Hae Ran Park, Eun Suk Sohn, Sang Won Lee, Hyung Don Kim, Young Chang Kim, Kee Hong Kim, Sae Won Na, Hyung-Kyoon Choi, Mariadhas Valan Arasu and Young Ock Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:455
    Content type: Research article Published on:

  47. Agaricus brasiliensis (A. brasiliensis) is a medicinal mushroom that exerts various pharmacological actions. We previously demonstrated that different cultivation conditions altered the activity of the polypheno...

    Authors: Daisuke Yamanaka, Masuro Motoi, Akitomo Motoi and Naohito Ohno
    Citation: BMC Complementary and Alternative Medicine 2014 14:454
    Content type: Research article Published on:

  48. Gal-geun-dang-gwi-tang (GGDGT), an herbal medicine, is used to treat hypertension, stroke, and other inflammatory disorders in the clinical setting. Recently, GGDGT was recognized by the Korea Institute of Ori...

    Authors: So Min Lee, Yun Jung Lee, Jung Hoon Choi, Min Chul Kho, Jung Joo Yoon, Sun Ho Shin, Dae Gill Kang and Ho Sub Lee
    Citation: BMC Complementary and Alternative Medicine 2014 14:453
    Content type: Research article Published on:

  49. Sonchus arvesis is traditionally reported in various human ailments including hepatotoxicity in Pakistan. Presently we designed to assess the protective effects of methanolic extract of Sonchus arvesis against c...

    Authors: Huda Mohammad Alkreathy, Rahmat Ali Khan, Muhammad Rashid Khan and Sumaira Sahreen
    Citation: BMC Complementary and Alternative Medicine 2014 14:452
    Content type: Research article Published on:

  50. Spinal cord injury (SCI)-induced secondary oxidative stress associates with a clinical complication and high mortality. Treatments to improve the neurological outcome of secondary injury are considered as impo...

    Authors: Chi-Long Juang, Fei Shish Yang, Ming Shuang Hsieh, Hu-Yi Tseng, Su-Chiu Chen and Hsiao-Chuan Wen
    Citation: BMC Complementary and Alternative Medicine 2014 14:447
    Content type: Research article Published on:
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