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  1. The rhizome of Curcuma aeruginosa Roxb (Zingiberaceae) has been used as a traditional folk medicine for the treatment of rheumatic disorders in Bangladesh. The aim of the current study was the bioassay-guided iso...

    Authors: Chowdhury Faiz Hossain, Mohammad Al-Amin, Abu Sadat Md. Sayem, Ismail Hossain Siragee, Asif Mahmud Tunan, Fahima Hassan, Md. Mohiuddin Kabir and Gazi Nurun Nahar Sultana
    Citation: BMC Complementary and Alternative Medicine 2015 15:191
  2. In order to facilitate the completeness and transparency of reporting on randomized controlled trials undertaken using acupuncture interventions, a consensus group of international experts developed the Standards...

    Authors: Lizhou Liu, Margot Skinner, Suzanne M McDonough, Priya Kannan and George David Baxter
    Citation: BMC Complementary and Alternative Medicine 2015 15:190
  3. Considering that adjuvant arthritis is an experimental model of arthritis widely used for preclinical testing of numerous anti-arthritic agents, which were taken by a large number of patients worldwide, it is ...

    Authors: Lívia G. Castilhos, João F. P. Rezer, Jader B. Ruchel, Maria Luiza Thorstenberg, Jeandre A. dos S. Jaques, Josiane B. Schlemmer, Pedro H. Doleski, Mateus F. Rossato, Mariane A. da Silva, Emerson André Casalli, Ritiel Corrêa da Cruz, Juliano Ferreira, Margareth L. Athayde, Jamile F. Gonçalves and Daniela B. R. Leal
    Citation: BMC Complementary and Alternative Medicine 2015 15:189
  4. Insulin resistance is characterized by deficient responses to insulin in its target tissues. In the present study, we examined the effects of L-Citrulline (L-Cit) on insulin sensitivity and signaling cascades ...

    Authors: Hisae Yoshitomi, Maki Momoo, Xiao Ma, Yewei Huang, Shiori Suguro, Yoshie Yamagishi and Ming Gao
    Citation: BMC Complementary and Alternative Medicine 2015 15:188
  5. Embelia schimperi has been used for the treatment of intestinal parasites especially tapeworm infestations for centuries in Ethiopia. However, there is lack of scientific based evidences regarding the efficacy, s...

    Authors: Yared Debebe, Mesfin Tefera, Walelign Mekonnen, Dawit Abebe, Samuel Woldekidan, Abiy Abebe, Yehualashet Belete, Temesgen Menberu, Bethelhem Belayneh, Berhanu Tesfaye, Ibrahim Nasir, Kidist Yirsaw, Hirut Basha, Asrat Dawit and Asfaw Debella
    Citation: BMC Complementary and Alternative Medicine 2015 15:187
  6. Baeckea frutescens is a natural remedy recorded to be used in curing various health conditions. In Peninsular Malaysia, B. frutescens is found on the mountain tops, quartz ridge and sandy coasts. To our knowledge...

    Authors: Suerialoasan Navanesan, Norhanom Abdul Wahab, Sugumaran Manickam and Kae Shin Sim
    Citation: BMC Complementary and Alternative Medicine 2015 15:186
  7. Oligonol is a low molecular weight form of polyphenol polymers derived from lychee fruits. Several studies suggest that Oligonol has an anti-obesity effect. Since obesity is tightly associated with insulin res...

    Authors: Jae-Yeo Park, Younghwa Kim, Jee Ae Im and Hyangkyu Lee
    Citation: BMC Complementary and Alternative Medicine 2015 15:185
  8. Continuous emergence of multi-drug-resistant malaria parasites and their rapid spread across the globe warrant urgent search for new anti-malarial chemotherapeutics. Traditional medicinal plants have been the ...

    Authors: Senait Girma, Mirutse Giday, Berhanu Erko and Hassen Mamo
    Citation: BMC Complementary and Alternative Medicine 2015 15:184
  9. Vaginal epithelial cells (VECs) produce antimicrobial peptides including human β-defensin 2 (hBD2) and secretory leukocyte protease inhibitor (SLPI), as well as cytokines and chemokines that play vital roles i...

    Authors: Surada Satthakarn, Florian Hladik, Aornrutai Promsong and Wipawee Nittayananta
    Citation: BMC Complementary and Alternative Medicine 2015 15:183
  10. In Traditional Tibetan medicine, Yukyung Karne has been used for the treatment of ovarian cancer. Though Yukyung Karne has been reported to be clinically effective, the molecular mechanism of its anti-metstatic a...

    Authors: Tenzin Choedon, Ganeshan Mathan and Vijay Kumar
    Citation: BMC Complementary Medicine and Therapies 2015 15:182
  11. Breast cancer remains a major health problem worldwide, and is becoming increasingly resistant to traditional drug treatments. For instance, Adriamycin (ADR) is beneficial for the treatment of breast cancer. H...

    Authors: Ye He, Jie Ding, Yan Lin, Juan Li, Yongguo Shi, Juan Wang, Ya Zhu, Keming Wang and Xuezhen Hu
    Citation: BMC Complementary and Alternative Medicine 2015 15:181
  12. In a previous randomised controlled trial we showed that acupuncture with a combination of manual- and electrical stimulation (EA) did not affect the level of pain, as compared with acupuncture with manual sti...

    Authors: Linda Vixner, Lena B. Mårtensson and Erica Schytt
    Citation: BMC Complementary and Alternative Medicine 2015 15:180
  13. New sources for discovering novel antiviral agents are desperately needed. The current antiviral products are both expensive and not very effective.

    Authors: Rand R Hafidh, Ahmed S Abdulamir, Fatimah Abu Bakar, Zamberi Sekawi, Fatemeh Jahansheri and Farid Azizi Jalilian
    Citation: BMC Complementary and Alternative Medicine 2015 15:179
  14. The inhibition of penicillin-binding protein 2a (PBP2a) is a promising solution in overcoming resistance of methicillin resistance Staphylococcus aureus (MRSA). A potential approach in achieving this is by combin...

    Authors: Carolina Santiago, Ee Leen Pang, Kuan-Hon Lim, Hwei-San Loh and Kang Nee Ting
    Citation: BMC Complementary and Alternative Medicine 2015 15:178
  15. Phellodendron amurense, exhibits antifungal activity mainly by bioactive components including berberine hydrochloride and palmatine hydrochloride. This study was conducted to evaluate the antifungal effects of be...

    Authors: Chen-Wen Xiao, Quan-An Ji, Qiang Wei, Yan Liu and Guo-Lian Bao
    Citation: BMC Complementary and Alternative Medicine 2015 15:177
  16. Laughter Yoga consists of physical exercise, relaxation techniques and simulated vigorous laughter. It has been associated with physical and psychological benefits for people in diverse clinical and non-clinic...

    Authors: Paul N Bennett, Trisha Parsons, Ros Ben-Moshe, Merv Neal, Melissa K Weinberg, Karen Gilbert, Cherene Ockerby, Helen Rawson, Corinne Herbu and Alison M Hutchinson
    Citation: BMC Complementary and Alternative Medicine 2015 15:176
  17. Protein cross-linking which occurs towards the latter part of protein glycation is implicated in the development of chronic diabetic complications. Glycation induced protein cross-linking inhibitory effects of...

    Authors: Handunge Kumudu Irani Perera and Charith Sandaruwan Handuwalage
    Citation: BMC Complementary and Alternative Medicine 2015 15:175
  18. Nefang is a polyherbal anti-malarial composed of Mangifera indica (MiB and MiL; bark and leaf), Psidium guajava (Pg), Carica papaya (Cp), Cymbopogon citratus (Cc), Citrus sinensis (Cs) and Ocimum gratissimum (Og)

    Authors: Protus Arrey Tarkang, Faith A. Okalebo, Juma D. Siminyu, William N. Ngugi, Amos M. Mwaura, Jackson Mugweru, Gabriel A. Agbor and Anastasia N. Guantai
    Citation: BMC Complementary and Alternative Medicine 2015 15:174
  19. Dizziness and vertigo account for roughly 4% of chief symptoms in the emergency department (ED). Pharmacological therapy is often applied for these symptoms, such as vestibular suppressants, anti-emetics and b...

    Authors: Chih-Wen Chiu, Tsung-Chieh Lee, Po-Chi Hsu, Chia-Yun Chen, Shun-Chang Chang, John. Y. Chiang and Lun-Chien Lo
    Citation: BMC Complementary and Alternative Medicine 2015 15:173
  20. Today, the increasing demand for complementary medicine encourages health care providers to adapt and create integrative medicine departments or services within clinics. However, because of their differing phi...

    Authors: Marion Pérard, Nadine Mittring, David Schweiger, Christopher Kummer and Claudia M. Witt
    Citation: BMC Complementary and Alternative Medicine 2015 15:172
  21. Oxidative stress is involved in neuronal cell death and mitochondrial dysfunction in neurodegenerative diseases. Liriope platyphylla (LP) has been suggested to have anti-inflammation, anti-bacterial, and anti-can...

    Authors: Hee Ra Park, Heeeun Lee, Hwayong Park, Jong Wook Jeon, Won-Kyung Cho and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2015 15:171
  22. Many patients with human immunodeficiency virus infection use traditional, complementary, and alternative medicines and other practices to combat the disease, with some also using prescribed antiretroviral the...

    Authors: Manimbulu Nlooto
    Citation: BMC Complementary and Alternative Medicine 2015 15:170
  23. Heliotropium strigosum is used in traditional medicine to manage gastrointestinal pain, respiratory distress and vascular disorders. The present study was undertaken to provide scientific evidences for these folk...

    Authors: Khalid H. Janbaz, Sana Javed, Fatima Saqib, Imran Imran, Muhammad Zia-Ul-Haq and Vincenzo De Feo
    Citation: BMC Complementary and Alternative Medicine 2015 15:169
  24. The prevalence of allergic diseases such as asthma has significantly increased worldwide, making it a public health concern. There is an urgent need for new anti-inflammatory agents with selective pharmacology...

    Authors: Marta Santos Serafim Machado, Hugo Bernardino Ferreira Silva, Raimon Rios, Anaque Pires de Oliveira, Noma Vilany Queiroz Carneiro, Ryan Santos Costa, William Santos Alves, Fabio-Luis Meneses Souza, Eudes da Silva Velozo, Silvana Alves de Souza, Tania Maria Sarmento Silva, Maria Lenise Silva, Lain Carlos Pontes-de-Carvalho, Neuza Maria Alcântara-Neves and Camila Alexandrina Figueiredo
    Citation: BMC Complementary and Alternative Medicine 2015 15:168
  25. Mind-body therapies are beneficial for several diseases (e.g. chronic pain, arterial hypertension, mood disorders). Eurythmy therapy (EYT) is a mind-body therapy from Anthroposophic Medicine. In each EYT exercise...

    Authors: Friedrich Edelhäuser, Antje Minnerop, Barbara Trapp, Arndt Büssing and Dirk Cysarz
    Citation: BMC Complementary and Alternative Medicine 2015 15:167
  26. Excessive production of inflammatory mediators such as nitric oxide (NO) and proinflammatory cytokines like tumour necrosis factor-alpha (TNF-α) from activated microglia contributes to uncontrolled inflammatio...

    Authors: Azzeme Harun, Sharmili Vidyadaran, Siong Meng Lim, Anthony L J Cole and Kalavathy Ramasamy
    Citation: BMC Complementary and Alternative Medicine 2015 15:166
  27. 3beta,6beta,16beta-trihydroxylup-20(29)-ene is a lupane triterpene isolated from Combretum leprosum fruit. The lupane group has been extensively used in studies on anticancer effects; however, its possible activi...

    Authors: Carolina Bioni Garcia Teles, Leandro Soares Moreira-Dill, Alexandre de Almeida Silva, Valdir Alves Facundo, Walter F. de Azevedo Jr, Luiz Hildebrando Pereira da Silva, Maria Cristina M. Motta, Rodrigo Guerino Stábeli and Izaltina Silva-Jardim
    Citation: BMC Complementary and Alternative Medicine 2015 15:165
  28. Anecdotally, use of Complementary and Alternative Medicine (CAM) for Musculoskeletal Pain (MSP) is common in Nigeria; however, there seems to be a dearth of empirical data on its prevalence and mode of use. Th...

    Authors: Chidozie Emmanuel Mbada, Tijani Lukman Adeyemi, Rufus Adesoji Adedoyin, Hakeem David Badmus, Taofeek Oluwole Awotidebe, Olujide Olusesan Arije and Olorunfemi Sunday Omotosho
    Citation: BMC Complementary and Alternative Medicine 2015 15:164
  29. Chinese herbal products (CHPs) have been frequently used among patients with chronic diseases including hypertension; however, the co-prescription pattern of herbal formulae and single herbs remain uncharacter...

    Authors: Pei-Rung Yang, Wei-Tai Shih, Yen-Hua Chu, Pau-Chung Chen and Ching-Yuan Wu
    Citation: BMC Complementary and Alternative Medicine 2015 15:163
  30. Nowadays, medicinal plants are used as a popular alternative to synthetic drugs. Many medicinal plant products have now been commercialized throughout various markets. These products are commonly sold in proce...

    Authors: Sahachat Singtonat and Maslin Osathanunkul
    Citation: BMC Complementary and Alternative Medicine 2015 15:162
  31. The dried roots of Scutellaria baicalensis Georgi, is known in traditional Chinese medicine as Huang Qin (H. qin), and it has been officially and traditionally used in treatment of various diseases such as hep...

    Authors: Yi Liu, Feng Ye, Wen-jing Zou, Ye Sun, Rui Wang, Ping-ping Han, Zhe Zhang, Xue-liang Yang and Xiaojin Liu
    Citation: BMC Complementary and Alternative Medicine 2015 15:161
  32. Nanotechnology has potential future for enhancing therapeutic efficacy and reducing the unwanted effects of herbal drugs. The biological research on Euphorbia species has been supported by the use of some plants ...

    Authors: Nazar Ul Islam, Ibrahim Khan, Abdur Rauf, Naveed Muhammad, Muhammad Shahid and Mohammad Raza Shah
    Citation: BMC Complementary and Alternative Medicine 2015 15:160
  33. Inflammation is a common risk factor in the pathogenesis of conditions such as infections, arthritis, type 2 diabetes mellitus, obesity and cancer. An ethnobotanical survey of medicinal plants used traditional...

    Authors: Salmon A. Adebayo, Jean P. Dzoyem, Leshweni J. Shai and Jacobus N. Eloff
    Citation: BMC Complementary and Alternative Medicine 2015 15:159
  34. Kaempferia galanga is an important medicinal plant and has been traditionally used to help restlessness, stress, anxiety, depression etc. in tropics and subtropics of Asia including Bangladesh, India, China, Japa...

    Authors: Mohammad Shawkat Ali, Pritesh Ranjan Dash and Mahmuda Nasrin
    Citation: BMC Complementary and Alternative Medicine 2015 15:158
  35. Uncaria sinensis (US) has long been used in traditional Korean medicine to relieve various nervous-related symptoms and cardiovascular disease. We recently showed the neuroprotective and cerebrovascular protectiv...

    Authors: Hyung Bum Seo, Bo Kyung Kang, Ji Hyun Kim, Young Whan Choi, Jin Woo Hong, Byung Tae Choi and Hwa Kyoung Shin
    Citation: BMC Complementary and Alternative Medicine 2015 15:157
  36. Propolis is the bee product noted for multiple biological effects, and therefore it is widely used for the prevention and treatment of a variety of diseases. The active substances of propolis are easily solubl...

    Authors: Loreta Kubiliene, Virginija Laugaliene, Alvydas Pavilonis, Audrius Maruska, Daiva Majiene, Karolina Barcauskaite, Raimondas Kubilius, Giedre Kasparaviciene and Arunas Savickas
    Citation: BMC Complementary and Alternative Medicine 2015 15:156
  37. Yi Qi Qing Re Gao (YQQRG) formula is a traditional Chinese herbal medicine used to treat chronic nephritis. This study was designed to evaluate the underlying mechanism in the use of YQQRG formula to treat nep...

    Authors: Yumin Wen, Yongli Zhan, Huijie Liu, Tingting Zhao, Liping Yang, Haojun Zhang, Xi Dong and Ping Li
    Citation: BMC Complementary and Alternative Medicine 2015 15:155
  38. As an important traditional Tibetan (veterinary) medicine, the flowers of Meconopsis punicea (family Papaveraceae) have been used to treat pain, fever, cough, inflammation, liver heat and lung heat of humans and ...

    Authors: Xiaofei Shang, Dongsheng Wang, Xiaolou Miao, Yu Wang, Jiyu Zhang, Xuezhi Wang, Yu Zhang and Hu Pan
    Citation: BMC Complementary and Alternative Medicine 2015 15:154
  39. The aim of this study was to investigate the mechanisms underlying the therapeutic effect of Uygur medicine KJA on UC in a rat model.

    Authors: Kurexi Yunusi, Jingping Zhang, Li Zhong, Gulinisha Mosha, Ajiguli Nuermaimaiti, Mairipaiti Abudula and Halmurat Upur
    Citation: BMC Complementary and Alternative Medicine 2015 15:152
  40. Parkinson’s disease (PD) is a chronic neurodegenerative disorder characterized by a loss of dopaminergic neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal motor...

    Authors: Hong Guo, Fang Shi, Meijiao Li, Qingqing Liu, Bin Yu and Limin Hu
    Citation: BMC Complementary and Alternative Medicine 2015 15:151
  41. Functional dyspepsia (FD), which is a very common disorder worldwide, is known to be caused by multiple factors including environmental and genetic factors. Sasang constitutional medicine (SCM) is a component ...

    Authors: Yoon Jeong Kim, Yo Chan Ahn and Chang Gue Son
    Citation: BMC Complementary and Alternative Medicine 2015 15:150
  42. Accumulating evidence has shown that chronic cerebral ischemia (CCI) is one of the major causes of vascular dementia (VD) characterized by dysregulated cholesterol homeostasis and lipoprotein disturbances. Pos...

    Authors: Xiaodan Song, Wenliang Zhu, Ran An, Yamei Li and Zhimin Du
    Citation: BMC Complementary and Alternative Medicine 2015 15:149
  43. Cystic fibrosis (CF) leads to advanced lung disease despite aggressive care. Persistent inflammation and oxidative stress contribute to exacerbations and disease progression. Flaxseed (FS), a dietary botanical...

    Authors: Jason B Turowski, Ralph A Pietrofesa, John A Lawson, Melpo Christofidou-Solomidou and Denis Hadjiliadis
    Citation: BMC Complementary and Alternative Medicine 2015 15:148
  44. Electroacupuncture (EA) is reported to be an effective treatment for obesity, but its mechanism is unclear. This study aimed to investigate the relationship between hypothalamic LKB1-AMPK-ACC signaling and EA.

    Authors: Jing Xu, Liang Chen, Lewei Tang, Le Chang, Si Liu, Jinfeng Tan, Yinglong Chen, Yulan Ren, Fanrong Liang and Jin Cui
    Citation: BMC Complementary and Alternative Medicine 2015 15:147
  45. Geranium wilfordii is one of the major species used as Herba Geranii (lao-guan-cao) in China, it is commonly used solely or in polyherbal formulations for treatment of joint pain resulted from rheumatoid arthriti...

    Authors: Min Huang, Pei-Wun Yao, Margaret Dah-Tysr Chang, Sim-Kun Ng, Chien-Hui Yu, Yun-feng Zhang, Meng-Liang Wen, Xiao-yuan Yang and Yiu-Kay Lai
    Citation: BMC Complementary and Alternative Medicine 2015 15:146
  46. Dementia is a prevalent neurodegenerative disorder affecting an estimated 24.3 million people across the globe. The burden on those caring for people with dementia is substantial, with widespread implications ...

    Authors: Matthew J. Leach, Andrew Francis and Tahereh Ziaian
    Citation: BMC Complementary and Alternative Medicine 2015 15:145
  47. Chronic tension-type headache (CTTH) is characterized by almost daily headaches and central sensitization, for which electroacupuncture (EA) might be effective. The central nervous system (CNS) plasticity can ...

    Authors: Mônica Chassot, Jairo Alberto Dussan-Sarria, Francislea Cristina Sehn, Alícia Deitos, Andressa de Souza, Rafael Vercelino, Iraci LS Torres, Felipe Fregni and Wolnei Caumo
    Citation: BMC Complementary and Alternative Medicine 2015 15:144
  48. Decision-making during pregnancy regarding different options of care can be difficult, particularly when risks of intervention versus no intervention for mother and baby are unclear. Unbiased information and s...

    Authors: Bettina Berger, Christiane Schwarz and Peter Heusser
    Citation: BMC Complementary and Alternative Medicine 2015 15:143
  49. Though traditional Korean medicine plays an important role in the Korean parallel health care system, there is limited information about the preference and usage of traditional Korean medicine compared to West...

    Authors: In-Hwan Oh, Seok-Jun Yoon, Minjung Park and SoHee An
    Citation: BMC Complementary and Alternative Medicine 2015 15:141