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  1. Kaixinjieyu (KJ), derived from Kaixin and Sini powder, is an effective Chinese herbal medicine preparation used in the treatment of vascular depression (VD). We hypothesize that broad antidepressant effect of ...

    Authors: Juhua Pan, Xiaoming Lei, Jialong Wang, Shijing Huang, Yanyun Wang, Ying Zhang, Wen Chen, Duojiao Li, Jun Zheng, Hanming Cui and Qihua Liu
    Citation: BMC Complementary and Alternative Medicine 2015 15:291
  2. Postinfectious cough (PIC) is a common condition that affects millions of people worldwide every year. There is Western medicine for this condition but the treatment effect is often incomplete. Traditional Chi...

    Authors: Wei Liu, Hongli Jiang, Ruiming Zhang, Faguang Jin, Liangji Liu, Youyu Long, Liying Cui, Suyun Li, Yunqing Zhong and Bing Mao
    Citation: BMC Complementary and Alternative Medicine 2015 15:290
  3. Boiled aqueous extract of flowers (AEF) from Nyctanthes arbor-tristis L. are used in Sri Lankan traditional Ayruvedic Medicine to manage diabetes mellitus. AEF has widely been used as a folk medicine for the trea...

    Authors: Bramanage Sachini Rangika, Pavithra Dilakshini Dayananda and Dinithi Champika Peiris
    Citation: BMC Complementary and Alternative Medicine 2015 15:289
  4. Rhododendron anthopogonoides Maxim, a kind of traditional Tibetan medicine, has been used to remove body heat, body detoxification, cough, asthma, stomachic and swelling, eliminate abundant phlegm and inflammator...

    Authors: Linlin Jing, Huiping Ma, Pengcheng Fan, Rongmin Gao and Zhengping Jia
    Citation: BMC Complementary and Alternative Medicine 2015 15:287
  5. To overcome the escalating problems associated with infectious diseases and drug resistance, discovery of new antimicrobials is crucial. The present study aimed to carry out in vitro antimicrobial analysis of 15 ...

    Authors: Alemtshay Teka, Johana Rondevaldova, Zemede Asfaw, Sebsebe Demissew, Patrick Van Damme, Ladislav Kokoska and Wouter Vanhove
    Citation: BMC Complementary and Alternative Medicine 2015 15:286
  6. Aiweixin (AWX) is a traditional Uyghur medicine prescription, and has been mainly used to treat heart and brain diseases for a long time. Previous studies indicated that AWX had therapeutic effects in a rat mo...

    Authors: Binggen Zhu, Ping Yang, Nurahmat Mammat, Hui Ding, Junmin He, Yong Qian, Jian Fei and Kaiser Abdukerim
    Citation: BMC Complementary and Alternative Medicine 2015 15:285
  7. Cisplatin (CDDP) is a highly effective chemotherapeutic agent used for therapy of many tumors and has been limited by its toxicity. Zengmian Yiliu granule (ZMYL), a compound preparation of traditional Chinese ...

    Authors: Can Gong, Lin Qian, Hong Yang, Li-li Ji, Hai Wei, Wen-bin Zhou, Cong Qi and Chang-hong Wang
    Citation: BMC Complementary and Alternative Medicine 2015 15:283
  8. The traditional use of the oleo-gum-resin of Commiphora guidottii Chiov. ex. Guid., which is commonly called scented myrrh, for topical treatment of wound is well documented. The major objective of the present st...

    Authors: Michael Gebrehiwot, Kaleab Asres, Daniel Bisrat, Avijit Mazumder, Peter Lindemann and Franz Bucar
    Citation: BMC Complementary and Alternative Medicine 2015 15:282
  9. Protein kinase C regulates various cellular processes including cell proliferation, cell adhesion, apoptosis, angiogenesis, invasion, and metastasis. Activation of different PKC isozymes results in distinct ce...

    Authors: Sudha Mishra and Manjula Vinayak
    Citation: BMC Complementary and Alternative Medicine 2015 15:281
  10. Natural plants, including common vegetables and fruits, have been recognized as essential sources for drug discovery and the development of new, safe, and economical medicaments. Stauntonia hexaphylla (Lardizabal...

    Authors: Yoon-Hee Cheon, Jong Min Baek, Sun-Hyang Park, Sung-Jun Ahn, Myeung Su Lee, Jaemin Oh and Ju-Young Kim
    Citation: BMC Complementary and Alternative Medicine 2015 15:280
  11. Gastrointestinal microbial communities are diverse and are composed of both beneficial and pathogenic groups. Prebiotics, such as digestion-resistant fibers, influence the composition of gut microbiota, and ca...

    Authors: Jinghua Liu, Saveetha Kandasamy, Junzeng Zhang, Christopher W. Kirby, Tobias Karakach, Jeff Hafting, Alan T. Critchley, Franklin Evans and Balakrishnan Prithiviraj
    Citation: BMC Complementary and Alternative Medicine 2015 15:279
  12. African trypanosomiasis affects both humans and livestock in sub-Saharan countries including Ethiopia. Due to limitations to current chemotherapy, there is an urgent need for the development of new, safe, chea...

    Authors: Belay Tadesse, Getachew Terefe, Nigatu Kebede and Workineh Shibeshi
    Citation: BMC Complementary and Alternative Medicine 2015 15:278
  13. To investigate the ameliorated effects of an extract of Ginkgo biloba extract (GBE) on experimental cardiac remodeling in rats induced by acute cardiac infarction, and further explore the mechanism concentrated o...

    Authors: Wei Li, Zhenhua Luo, Xingde Liu, Lingyun Fu, Yini Xu, Lirong Wu and Xianchun Shen
    Citation: BMC Complementary and Alternative Medicine 2015 15:277
  14. Authors: Sung Min Ahn, Yu Ri Kim, Ha Neui Kim, Young Whan Choi, Jae Won Lee, Cheol Min Kim, Jin Ung Baek, Hwa Kyoung Shin and Byung Tae Choi
    Citation: BMC Complementary and Alternative Medicine 2015 15:276

    The original article was published in BMC Complementary and Alternative Medicine 2015 15:202

  15. Over the recent decades complementary and alternative medicine (CAM) use within and outside of the public health care system in Norway has increased. The aim of this study is to describe to what extent CAM is ...

    Authors: R Jacobsen, V. M. Fønnebø, N. Foss and A. E. Kristoffersen
    Citation: BMC Complementary and Alternative Medicine 2015 15:275
  16. In this study, we investigated the effects of an extract of the leaves of Porophyllum ruderale and laser irradiation on the healing of burns.

    Authors: Ana Cristina Justino Jácomo, Karina de Andrade Velozo, Raquel Gabilan Lotti, Lia Mara Grosso Neves, Fernanda Oliveira de Gaspari de Gaspi, Marcelo A. Marreto Esquisatto, Maria Esméria Corezola do Amaral, Fernanda A. Sampaio Mendonça and Gláucia Maria Tech dos Santos
    Citation: BMC Complementary and Alternative Medicine 2015 15:274
  17. Xiao-Ke-An (XKA) is a Chinese medicine widely used for treating type 2 diabetes mellitus (T2D). It is composed of eight herbal medicines traditionally used for T2D, including Rehmannia glutinosa Libosch, Anemarrh...

    Authors: Zhenzhong Yang, Linli Wang, Feng Zhang and Zheng Li
    Citation: BMC Complementary and Alternative Medicine 2015 15:272
  18. Retinal neovascularization is a common cause of vision loss in proliferative diabetic retinopathy, retinopathy of prematurity and age-related macular degeneration. Samul-tang (SMT) is a widely used traditional...

    Authors: Yun Mi Lee, Chan-Sik Kim, Kyuhyung Jo, Eun Jin Sohn, Jin Sook Kim and Junghyun Kim
    Citation: BMC Complementary and Alternative Medicine 2015 15:271
  19. The incidents of drug resistant microorganisms and the need of treatments for newly emerging pathogens are of great concern to the global community. Our ability to treat infectious diseases is dependent on the...

    Authors: Mekdes Megeressa, Daniel Bisrat, Avijit Mazumder and Kaleab Asres
    Citation: BMC Complementary and Alternative Medicine 2015 15:270
  20. Dyslipidaemia is highly associated with cardiovascular and cerebrovascular diseases, which have been ranked second and third place of leading causes of death in Taiwan. Some plant extracts have been proved eff...

    Authors: Chih-Wei Chang, Yi-Ju Hsu, Yi-Ming Chen, Wen-Ching Huang, Chi-Chang Huang and Mei-Chich Hsu
    Citation: BMC Complementary and Alternative Medicine 2015 15:269
  21. Methyl mercury (MeHg), an important environmental toxicant is implicated in neurological disorders such as Hunter-Russell syndrome and Autism. Therefore, the present work is in search of new drugs that can all...

    Authors: Dhanoop Manikoth Ayyathan, Rajasekaran Chandrasekaran and Kalaivani Thiagarajan
    Citation: BMC Complementary and Alternative Medicine 2015 15:268
  22. In Chinese medicine, dual effects on target organs are considered a primary characteristic of acupoint. Acupoints may be classified as heterotopic or homotopic in terms of spinal segmental innervation: homotop...

    Authors: Qingguang Qin, Qian Mo, Kun Liu, Xun He, Xinyan Gao and Bing Zhu
    Citation: BMC Complementary and Alternative Medicine 2015 15:267
  23. The integrated therapy of Bufei Yishen granule and acupoint sticking has been used in the treatment of stable chronic obstructive pulmonary disease (COPD) clinically, with remarkable benefits. This study was i...

    Authors: Yange Tian, Ya Li, Jiansheng Li, Yang Xie, Minghang Wang, Yuqiong Dong, Linlin Li, Jing Mao, Lili Wang and Shan Luo
    Citation: BMC Complementary and Alternative Medicine 2015 15:266
  24. Well known as teak, Tectona grandis is widely used in African folk medicine for its pharmacological relevance. In Cameroon, this species is a reputed laxative in the Northern Region while in the Western Region, i...

    Authors: Gabin Thierry M. Bitchagno, Leonard Sama Fonkeng, Théodora K. Kopa, Michel F. Tala, Hippolyte Kamdem Wabo, Christopher B. Tume, Pierre Tane and Jules-Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2015 15:265
  25. Arum palaestinum is a plant commonly found in the Middle East that is ingested as an herbal remedy to fight cancer. However, no studies have examined the direct effect of the plant/plant extract on tumor growth i...

    Authors: Caitlin Cole, Thomas Burgoyne, Annie Lee, Lisa Stehno-Bittel and Gene Zaid
    Citation: BMC Complementary and Alternative Medicine 2015 15:264

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2015 15:322

  26. Isolation of methyl gamma linolenate from Spirulina platensis using flash chromatography and its apoptosis inducing effect against human lung carcinoma A- 549 cell lines.

    Authors: Jubie S., Dhanabal S. P. and Chaitanya M. V. N. L.
    Citation: BMC Complementary and Alternative Medicine 2015 15:263
  27. Plant-derived molecules (PDMs) are known to be a rich source of diverse scaffolds that could serve as a basis for rational drug design. Structured compilation of phytochemicals from traditional medicinal plant...

    Authors: Shivalika Pathania, Sai Mukund Ramakrishnan, Vinay Randhawa and Ganesh Bagler
    Citation: BMC Complementary and Alternative Medicine 2015 15:262
  28. Astragalus membranaceus (AM) is a Chinese traditional herb which has been reported to have broad positive effects on many diseases, including hepatitis, heart disease, diabetes and skin disease. AM can promote ce...

    Authors: Xiaolong Jiang, Xia Cao, Yang Huang, Jianwei Chen, Xiaolei Yao, Miaomiao Zhao, Yan Liu, Jinzhu Meng, Pengfei Li, Zhiyan Li, Jianbo Yao, George W Smith and Lihua Lv
    Citation: BMC Complementary and Alternative Medicine 2015 15:261
  29. To evaluate the in vitro activities of Ethiopian Thymus schimperi with other three hydro distilled essential oils against Dermatophytes (Tricophyton spp. and Microsporum spp.) and other pathogenic micro organisms...

    Authors: Mohammed Nasir, Ketema Tafess and Dawit Abate
    Citation: BMC Complementary and Alternative Medicine 2015 15:260
  30. Pancreatic fibrosis is a prominent histopathological characteristic of chronic pancreatitis and plausibly a dynamic process of transition to the development of pancreatic ductal adenocarcinoma. Conversely, the...

    Authors: Zesi Lin, Lu-Cong Zheng, Hong-Jie Zhang, Siu Wai Tsang and Zhao-Xiang Bian
    Citation: BMC Complementary and Alternative Medicine 2015 15:259
  31. Analysis and extraction of plant matrices are important processes for the development, modernization, and quality control of herbal formulations. Response surface methodology is a collection of statistical and...

    Authors: Ali Ghasemzadeh, Hawa Z.E. Jaafar and Asmah Rahmat
    Citation: BMC Complementary and Alternative Medicine 2015 15:258
  32. The prevalence of Diabetes mellitus (DM) is escalating rapidly worldwide, and associated with micro- and macrovascular complications. Diabetic neuropathy (DN) is a common complication of DM, and has a few approve...

    Authors: K. Raafat and A. El-Lakany
    Citation: BMC Complementary and Alternative Medicine 2015 15:257
  33. Helicobacter pylori infection has been associated with chronic gastritis, peptic ulcer and gastric carcinoma as over half of the world's population is colonized with this gram-negative bacterium. Due to the incre...

    Authors: Angela Filocamo, Carlo Bisignano, Nadia Ferlazzo, Santa Cirmi, Giuseppina Mandalari and Michele Navarra
    Citation: BMC Complementary and Alternative Medicine 2015 15:256
  34. Long-term treatment of chronic hepatitis B (CHB) with nucleos(t)ide analogs results in the emergence of drug-resistant hepatitis B virus (HBV) harboring mutations in the polymerase (P) gene. The Phyllanthus extra...

    Authors: Jaesung Jung, Nam Keun Kim, Sun Park, Ho-Joon Shin, Seong Gyu Hwang and Kyongmin Kim
    Citation: BMC Complementary and Alternative Medicine 2015 15:255
  35. Reactive Oxygen Species (ROS) impair the physiological functions of Retinal Pigment Epithelial (RPE) cells, which are known as one major cause of age-related macular degeneration and retinopathy diseases. The ...

    Authors: Simon Bernard Iloki-Assanga, Lidianys María Lewis-Luján, Daniela Fernández-Angulo, Armida Andrea Gil-Salido, Claudia Lizeth Lara-Espinoza and José Luis Rubio-Pino
    Citation: BMC Complementary and Alternative Medicine 2015 15:254
  36. Cissampelos sympodialis (Menispermaceae), known as “Milona” has a specific verified medicinal use for the treatment of diarrhea and respiratory tract diseases. This work aims to evaluate the antimotility and anti...

    Authors: Igor Rafael Praxedes de Sales, Flavia Danniele Frota Machado, Alexsandro Fernandes Marinho, Ana Sílvia Suassuna Carneiro Lúcio, José Maria Barbosa Filho and Leônia Maria Batista
    Citation: BMC Complementary and Alternative Medicine 2015 15:253
  37. Drug-induced liver injury is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. The possible hepatoprotective effect of...

    Authors: Hend M. Tag
    Citation: BMC Complementary and Alternative Medicine 2015 15:252
  38. The liver is the most sensitive and main target organ of pesticide toxicity and damage, they play an essential role in metabolism and detoxification of pesticides. Due to these functions, hepatotoxicity contin...

    Authors: Abdel-Tawab H. Mossa, Tarek M. Heikal, Meriam Belaiba, Emmanuel Guy Raoelison, Hicham Ferhout and Jalloul Bouajila
    Citation: BMC Complementary and Alternative Medicine 2015 15:251
  39. Qing’e formula (QEF), prepared from an ancient Chinese recipe, was previously suggested to regulate bone metabolism and improve bone mineral density in patients with osteoporosis. To study the effects of medic...

    Authors: Bo Shuai, Lin Shen, Rui Zhu and Piqi Zhou
    Citation: BMC Complementary and Alternative Medicine 2015 15:250
  40. Leishmaniasis is an infectious disease caused by various species of the protozoan parasites of the Leishmania genus and transmitted by phlebotomine sandflies. The protozoa multiply in phagocytic cells, mainly mac...

    Authors: Raquel Raick P. da Silva, Bruno J. M. da Silva, Ana Paula D. Rodrigues, Luis Henrique S. Farias, Milton N. da Silva, Danila Teresa V. Alves, Gilmara N. T. Bastos, José Luiz M. do Nascimento and Edilene O. Silva
    Citation: BMC Complementary and Alternative Medicine 2015 15:249
  41. The intensive use of Praziquantel for the treatment of schistosomiasis has raised concerns about the possible emergence of drug-resistant schistosomes. As drug treatment is an important feature of schistosome ...

    Authors: Hermine Boukeng Jatsa, Christian Mérimé Kenfack, Distele Nadège Simo, Nestor Gipwe Feussom, Emilienne Tienga Nkondo, Louis-Albert Tchuem Tchuente, Christelle Dongmo Tsague, Etienne Dongo and Pierre Kamtchouing
    Citation: BMC Complementary and Alternative Medicine 2015 15:248
  42. Dendropanax morbifera Léveille has been employed for the treatment of infectious diseases using folk medicine. In this study, we evaluated the antioxidant effects of a leaf extract of Dendropanax morbifera Léveil...

    Authors: Woosuk Kim, Dae Won Kim, Dae Young Yoo, Hyo Young Jung, Jong Whi Kim, Dong-Woo Kim, Jung Hoon Choi, Seung Myung Moon, Yeo Sung Yoon and In Koo Hwang
    Citation: BMC Complementary and Alternative Medicine 2015 15:247
  43. Methotrexate (MTX) is an antimetabolite broadly used in treatment of cancer and autoimmune diseases. MTX-induced hepatotoxicity limits its application. We investigated hepatoprotective effects of turmeric in M...

    Authors: Adel Rezaei Moghadam, Soheil Tutunchi, Ali Namvaran-Abbas-Abad, Mina Yazdi, Fatemeh Bonyadi, Daryoush Mohajeri, Mohammad Mazani, Hassan Marzban, Marek J. Łos and Saeid Ghavami
    Citation: BMC Complementary and Alternative Medicine 2015 15:246
  44. Some patients receiving treatment in conventional health care systems access therapeutic yoga outside their mainstream care to improve cancer symptoms. Given the current knowledge gap around patient preference...

    Authors: Marcy McCall, Sally Thorne, Alison Ward and Carl Heneghan
    Citation: BMC Complementary and Alternative Medicine 2015 15:245
  45. The increasing numbers of people who use plant-based remedies as alternative or complementary medicine call for the validation of less known herbal formulations used to treat their ailments. Since Puerto Rico ...

    Authors: Jannette Gavillán-Suárez, Alexandra Aguilar-Perez, Natalie Rivera-Ortiz, Karla Rodríguez-Tirado, Wanda Figueroa-Cuilan, Lorelein Morales-Santiago, Gerónimo Maldonado-Martínez, Luis A. Cubano and Michelle M. Martínez-Montemayor
    Citation: BMC Complementary and Alternative Medicine 2015 15:244
  46. Traditional Chinese Medicine (TCM) has been applied in treating tuberculosis (TB) based on the TCM syndromes with the effects of inhibiting Mycobacterium, strengthening the body immune system, and reducing the...

    Authors: Ting-Ting Jiang, Chong Wang, Li-Liang Wei, Xiao-Mei Yu, Li-Ying Shi, Dan-Dan Xu, Zhong-Liang Chen, Ze-Peng Ping and Ji-Cheng Li
    Citation: BMC Complementary and Alternative Medicine 2015 15:243
  47. Moringa stenopetala has been used in traditional health systems to treat diabetes mellitus. The aim of this study was to investigate the antidiabetic activity of aqueous ethanol and n-butanol fraction of Moringa ...

    Authors: Alemayehu Toma, Eyasu Makonnen, Yelamtsehay Mekonnen, Asfaw Debella and Sirichai Adisakwattana
    Citation: BMC Complementary and Alternative Medicine 2015 15:242