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  1. Natural products display numerous therapeutic properties (e.g., antibacterial activity), providing the population with countless benefits. Therefore, the search for novel biologically active, naturally occurri...

    Authors: Fariza Abrão, Luciana Delfino de Araújo Costa, Jacqueline Morais Alves, Juliana Marques Senedese, Pâmela Tinti de Castro, Sérgio Ricardo Ambrósio, Rodrigo Cássio Sola Veneziani, Jairo Kenupp Bastos, Denise Crispim Tavares and Carlos Henrique G. Martins
    Citation: BMC Complementary and Alternative Medicine 2015 15:443
  2. Herbal supplements are widely used in the treatment of various liver disases, but some of them may also induce liver injuries. Regarding the infuence of thyme and its constituents on the liver, conflicting res...

    Authors: Aleksandar Rašković, Nebojša Pavlović, Maja Kvrgić, Jan Sudji, Gorana Mitić, Ivan Čapo and Momir Mikov
    Citation: BMC Complementary and Alternative Medicine 2015 15:442
  3. Descurainia sophia seeds have a variety of pharmacological functions and been widely used in traditional folk medicine. However, their effects on human drug metabolizing enzyme (DME) a...

    Authors: Jin-Mu Yi, Young Ah Kim, You Jin Lee, Ok-Sun Bang and No Soo Kim
    Citation: BMC Complementary and Alternative Medicine 2015 15:441
  4. Edible mushrooms, especially the genus of Pleurotus, have been well studied for their nutrition as well as non-toxic medicinal properties. Recently, much attention has been paid to the therapeutic values of mushr...

    Authors: Jianjun Zhang, Guangyuan Meng, Chen Zhang, Lin Lin, Nuo Xu, Min Liu, Fangyuan Cui and Le Jia
    Citation: BMC Complementary and Alternative Medicine 2015 15:440
  5. Tetracarpidium conophorum (Mull. Arg.) Hutch. & Dalz is one of the many medicinal plants used for ages in folklore as male fertility enhancers. The current study evaluates the effect o...

    Authors: S. F. Akomolafe, G. Oboh, A. A. Akindahunsi and A. J. Afolayan
    Citation: BMC Complementary and Alternative Medicine 2015 15:439
  6. Tamarindus indica L. (T. indica) or locally known as “asam jawa” belongs to the family Leguminosae. T. indica seeds as by-products from the fruits were previously reported to contain h...

    Authors: Nurhanani Razali, Sarni Mat Junit, Azhar Ariffin, Nur Siti Fatimah Ramli and Azlina Abdul Aziz
    Citation: BMC Complementary and Alternative Medicine 2015 15:438
  7. Bidens bipinnata are widely distributed in China, which have been widely used as a traditional Chinese medicine. The aim of this study was to examine the effect of total avonoids of Bidens pilosa L. (TFB) on a...

    Authors: Ai-Zong Shen, Xia Li, Wei Hu and Fei-Hu Chen
    Citation: BMC Complementary and Alternative Medicine 2015 15:437
  8. The present study aimed at examining whether methodological strategies from a previously implemented study design could be transferred to the evaluation of the psychological and physiological effects of a musi...

    Authors: Marco Warth, Jens Kessler, Svenja Kotz, Thomas K. Hillecke and Hubert J. Bardenheuer
    Citation: BMC Complementary and Alternative Medicine 2015 15:436
  9. Obesity is a worldwide public health issue, reaching epidemic condition in developing countries associated to chronic diseases. Oxidative damage is another side effect of obesity. Antioxidant activity from pla...

    Authors: Claudia Delgadillo Puga, Mario Cuchillo Hilario, José Guillermo Espinosa Mendoza, Omar Medina Campos, Eduardo Molina Jijón, Margarita Díaz Martínez, Marsela Alejandra Álvarez Izazaga, José Ángel Ledesma Solano and José Pedraza Chaverri
    Citation: BMC Complementary and Alternative Medicine 2015 15:435
  10. The aging kidney is marked by a chronic inflammation, which may exacerbate the progression of renal dysfunction, as well as increase the susceptibility to acute injury. The identification of strategies to alle...

    Authors: Elizabeth Grunz-Borgmann, Valeri Mossine, Kevin Fritsche and Alan R. Parrish
    Citation: BMC Complementary and Alternative Medicine 2015 15:434
  11. The beneficial effect of probiotics on renal profile and liver function has been reported among patients with chronic kidney disease and fatty liver respectively. However, its effect on renal profile and liver...

    Authors: Somayyeh Firouzi, Barakatun-Nisak Mohd-Yusof, Hazreen-Abd Majid, Amin Ismail and Nor-Azmi Kamaruddin
    Citation: BMC Complementary and Alternative Medicine 2015 15:433
  12. Patients seek Korean Medicine (KM) treatment for a broad range of complaints in Korea, but predominantly for musculoskeletal disorders. We investigated lumbar Intervertebral Disc Displacement (IDD) practice pa...

    Authors: Ye-sle Shin, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-riong Kim, Yong-jun Ahn, Ki Byung Park, Byung-Cheul Shin, Myeong Soo Lee, Joo-Hee Kim, Jae-Heung Cho and In-Hyuk Ha
    Citation: BMC Complementary and Alternative Medicine 2015 15:432
  13. Drastic increment of skin cancer incidence has driven natural product-based chemoprevention as a promising approach in anticancer drug development. Apart from its traditional usages against various ailments, Ardi...

    Authors: Looi Ting Yeong, Roslida Abdul Hamid, Latifah Saiful Yazan, Huzwah Khaza’ai and Norhafizah Mohtarrudin
    Citation: BMC Complementary and Alternative Medicine 2015 15:431
  14. Weight-loss medicines, including crude drugs and herbal supplements disguised as diet-aid products, are readily obtainable and distributed widely, especially in Southeast Asia. Even if such products are unappr...

    Authors: Naoko Yoshida, Midori Numano, Yoko Nagasaka, Kaori Ueda, Hirohito Tsuboi, Tsuyoshi Tanimoto and Kazuko Kimura
    Citation: BMC Complementary and Alternative Medicine 2015 15:430
  15. Achyrocline bogotensis has been traditionally used to treat infections of skin, respiratory, tract urinary and other infections, but not to treat viral gastrointestinal disease. In thi...

    Authors: M. A. Téllez, A. N. Téllez, F. Vélez and J. C. Ulloa
    Citation: BMC Complementary and Alternative Medicine 2015 15:428
  16. The larvae of Musca domestica (Diptera: Muscidae) have been used traditionally for malnutritional stagnation, decubital necrosis, osteomyelitis, ecthyma and lip scald and also to treat coma and gastric cancer in ...

    Authors: Liqing Chen, Juan Zhang and Hongxiang Sun
    Citation: BMC Complementary and Alternative Medicine 2015 15:427
  17. Pearl millet (PM), i.e., Pennisetum glaucum, is widely grown in Africa and known for its anti-oxidant and anti-hyperlipidemic properties.

    Authors: Abdelhafid Nani, Meriem Belarbi, Wided Ksouri-Megdiche, Souleymane Abdoul-Azize, Chahid Benammar, François Ghiringhelli, Aziz Hichami and Naim Akhtar Khan
    Citation: BMC Complementary and Alternative Medicine 2015 15:426
  18. Methicillin-resistant Staphylococcus aureus (MRSA) is a problematic pathogen posing a serious therapeutic challenge in the clinic. It is often multidrug-resistant (MDR) to conventional classes of antibacterial ag...

    Authors: Guo-Ying Zuo, Xin-Juan Zhang, Jun Han, Yu-Qing Li and Gen-Chun Wang
    Citation: BMC Complementary and Alternative Medicine 2015 15:425
  19. Suo Quan Wan (SQW) is a Chinese traditional prescription that has been used in clinical treatment of lower urinary tract symptoms for centuries. However, scientific basis of SQW efficacy and mechanism is still...

    Authors: Huanling Lai, Bo Tan, Zhijian Liang, Qitao Yan, Qingwang Lian, Qinghe Wu, Ping Huang and Hongying Cao
    Citation: BMC Complementary and Alternative Medicine 2015 15:424
  20. Some of the genus Rhododendron was used in traditional medicine for arthritis, acute and chronic bronchitis, asthma, pain, inflammation, rheumatism, hypertension and metabolic diseases and many species of the gen...

    Authors: Yu-Tang Tung, Lei-Chen Lin, Ya-Ling Liu, Shang-Tse Ho, Chi-Yang Lin, Hsiao-Li Chuang, Chien-Chao Chiu, Chi-Chang Huang and Jyh-Horng Wu
    Citation: BMC Complementary and Alternative Medicine 2015 15:423
  21. Strobilanthes crispus is a well-known herb in Malaysia with various pharmaceutical properties. S. crispus is known to contain several biologically active chemical constituents which are responsible for its pharma...

    Authors: Ali Ghasemzadeh, Hawa ZE Jaafar and Asmah Rahmat
    Citation: BMC Complementary and Alternative Medicine 2015 15:422
  22. Exposure to ultraviolet A (UVA) irradiation is the major cause of human skin aging. Suppression of UVA irradiation-induced skin fibroblast cell damage protects the skin against aging. An oxidative stress respo...

    Authors: Yuichi Saito, Kazuhiro Tsuruma, Kenji Ichihara, Masamitsu Shimazawa and Hideaki Hara
    Citation: BMC Complementary and Alternative Medicine 2015 15:421
  23. The Combretum leprosum Mart. plant, popularly known as mofumbo, is used in folk medicine for inflammation, pain and treatment of wounds. From this species, it is possible to isolate three triterpenes: (3β, 6β, 16

    Authors: Fabianne Lacouth-Silva, Caroline V. Xavier, Sulamita da S. Setúbal, Adriana S. Pontes, Neriane M. Nery, Onassis Boeri de Castro, Carla F. C. Fernandes, Eduardo R. Honda, Fernando B. Zanchi, Leonardo A. Calderon, Rodrigo G. Stábeli, Andreimar M. Soares, Izaltina Silva-Jardim, Valdir A. Facundo and Juliana P. Zuliani
    Citation: BMC Complementary and Alternative Medicine 2015 15:420
  24. With cancer being one of the major causes of death around the world, studies are ongoing to find new chemotherapeutic leads. There are common mechanisms for colorectal cancer (CRC) formation. Several are conne...

    Authors: Nawal Al-Henhena, Shaden A. M. Khalifa, Rozaida Poh Yuen Ying, Salmah Ismail, Riad Hamadi, Abdrabu N. Shawter, Azila Mohd Idris, Ainnul Azizan, Nahla Saeed Al-Wajeeh, Mahmood Ameen Abdulla and Hesham R. El-Seedi
    Citation: BMC Complementary and Alternative Medicine 2015 15:419
  25. Shenmai injection (SM), as a traditional Chinese medicine injection, is widely used for chronic cor pulmonale heart failure in mainland China. It is essential to systematically assess the efficacy and safety o...

    Authors: Liwei Shi, Yanming Xie, Xing Liao, Yan Chai and Yanhua Luo
    Citation: BMC Complementary and Alternative Medicine 2015 15:418

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2015 15:429

  26. Limitations of antifungal agents used in the treatment of oral candidiasis, as the development of resistant strains, are known by the scientific community. In this context, the aim of this study was to evaluat...

    Authors: Ricardo Dias de Castro, Trícia Murielly Pereira Andrade de Souza, Louise Morais Dornelas Bezerra, Gabriela Lacet Silva Ferreira, Edja Maria Melo de Brito Costa and Alessandro Leite Cavalcanti
    Citation: BMC Complementary and Alternative Medicine 2015 15:417
  27. The root bark of Zizyphus nummularia (Rhamnaceae) is traditionally used as an anti-inflammatory agent. The current study aimed to explore the anti-inflammatory activity (in vivo) of a crude ethanolic extract (EE)...

    Authors: Sarbani Dey Ray, Supratim Ray, Muhammad Zia-Ul-Haq, Vincenzo De Feo and Saikat Dewanjee
    Citation: BMC Complementary and Alternative Medicine 2015 15:416
  28. Salvia miltiorrhiza (SM), an herbal plant, is traditionally used in the treatment of cardiovascular and cerebrovascular diseases in Asian countries. SM has multiple biological effects including anti-inflammatory ...

    Authors: Min-Soo Kim, Ji Hye Bang, Jun Lee, Hyeon Woo Kim, Sang Hyun Sung, Jung-Soo Han and Won Kyung Jeon
    Citation: BMC Complementary and Alternative Medicine 2015 15:415
  29. Scoparia dulcis Linn (Scrophulariaceae) together with other medicinal plants serve as antisickling remedies in Africa. This study was aimed at investigating the antisickling activity of the leaves of the plant as...

    Authors: Tavs A. Abere, Chiagozie J. Okoye, Freddy O. Agoreyo, Gerald I. Eze, Rose I. Jesuorobo, Clement O. Egharevba and Pauline O. Aimator
    Citation: BMC Complementary and Alternative Medicine 2015 15:414
  30. Walnut is unique because they have a perfect balance of n-6 and n-3 polyunsaturated fatty acids. The increasing market demand of walnut lipids results in the large amount of the oil extraction residue. The wal...

    Authors: Sihui Ma, Di Huang, Mengxin Zhai, Lubing Yang, Sen Peng, Changxu Chen, Xiaoru Feng, Qiang Weng, Bolin Zhang and Meiyu Xu
    Citation: BMC Complementary and Alternative Medicine 2015 15:413
  31. The present study was designed to investigate the antibacterial activities of the methanol extracts from different parts of Beilschmedia acuta Kosterm (Lauraceae), Clausena anisata (Willd) Hook (Rutaceae), Newbou...

    Authors: Simplice B. Tankeo, Pierre Tane and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2015 15:412
  32. Breast cancer patients commonly report using >1 form of complementary and alternative medicine (CAM). However, few studies have attempted to analyze predictors and outcomes of multiple CAM modalities. We sough...

    Authors: Garrett Strizich, Marilie D. Gammon, Judith S. Jacobson, Melanie Wall, Page Abrahamson, Patrick T. Bradshaw, Mary Beth Terry, Susan Teitelbaum, Alfred I. Neugut and Heather Greenlee
    Citation: BMC Complementary and Alternative Medicine 2015 15:411
  33. Leaf extracts of Scoparia dulcis, is used as a herbal remedy by diabetics worldwide. Fresh Scoparia dulcis porridge elicited a low glycaemic index (GI) and anti-hyperglycaemic effects when fed to diabetic Wistar ...

    Authors: Senadheera Pathirannehelage Anuruddhika Subhashinie Senadheera, Sagarika Ekanayake and Chandanie Wanigatunge
    Citation: BMC Complementary and Alternative Medicine 2015 15:410
  34. Olea africana leaves are used by Bapedi people to treat different ailments. The use of these leaves is not validated, therefore the aim of this study is to validate antimicrobial properties of this plant.

    Authors: Peter Masoko and David M. Makgapeetja
    Citation: BMC Complementary and Alternative Medicine 2015 15:409
  35. The prevalence of diabetes mellitus (DM) continues to rise alarmingly despite years of intensive research. The need to explore alternative remedies such as traditional phytotherapy has therefore become increas...

    Authors: Kogi Moodley, Kimane Joseph, Yougasphree Naidoo, Shahidul Islam and Irene Mackraj
    Citation: BMC Complementary and Alternative Medicine 2015 15:408
  36. Ischemic stroke (IS) is a common disease, often resulting in death or disability. Previous studies on prognosis of stroke mainly focused on the baseline condition or modern expensive tests. However, the change...

    Authors: Ke-Gang Cao, Cai-Hong Fu, Huan-Qin Li, Xi-Yan Xin and Ying Gao
    Citation: BMC Complementary and Alternative Medicine 2015 15:407
  37. The number of colonoscopies tremendously increased in recent years and will further rise in the near future. Because of patients’ growing expectation on comfort during medical procedures, it is not surprising ...

    Authors: Susanne Eberl, Nelson Monteiro de Olivera, Benedikt Preckel, Konrad Streitberger, Paul Fockens and Markus W. Hollmann
    Citation: BMC Complementary and Alternative Medicine 2015 15:406
  38. Combretum zeyheri, belongs to the family Combretaceae and is one of the most popular herbal plants in tropical and subtropical countries. The leaves of Combretum zeyheri have been used as herbal medicine and have...

    Authors: Rumbidzai Mangoyi, Jacob Midiwo and Stanley Mukanganyama
    Citation: BMC Complementary and Alternative Medicine 2015 15:405
  39. During the past few years, there has been an increasing interest among the Traditional and Folk medical practitioners of Sri Lanka in the use of a decoction prepared from Flueggea leucopyrus (Willd.) for treating...

    Authors: Anuka S. Mendis, Ira Thabrew, Sameera R. Samarakoon and Kamani H. Tennekoon
    Citation: BMC Complementary and Alternative Medicine 2015 15:404
  40. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder clinically characterized by loss of memory and cognition. Cholinergic deficit and oxidative stress have been implicated in the pathogenesis ...

    Authors: Md. Moniruzzaman, Md. Asaduzzaman, Md. Sarwar Hossain, Jyotirmoy Sarker, S. M. Abdur Rahman, Mamunur Rashid and Md. Mosiqur Rahman
    Citation: BMC Complementary and Alternative Medicine 2015 15:403
  41. Increasing studies have shown that dyslipidemia and inflammatory responses play important roles in the progression of microvascular diabetic complications. Esculin (ES), a coumarin derivative, was extracted from

    Authors: Yue-Hua Wang, Yan-Hong Liu, Guo-Rong He, Yang Lv and Guan-Hua Du
    Citation: BMC Complementary and Alternative Medicine 2015 15:402
  42. Hydnora abyssinica (HA) A. Braun is an endemic Sudanese medicinal plant traditionally used as anti-inflammatory and against many infectious diseases. However, it proved to be very rich in phenols and tannins, so ...

    Authors: Waleed S. Koko, Mohamed A. Mesaik, Rosa Ranjitt, Mohamed Galal and Muhammad I. Choudhary
    Citation: BMC Complementary and Alternative Medicine 2015 15:400
  43. Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and is highly prevalent in populations with metabolic conditions such as obesity and type II diabetes. Specific types...

    Authors: Seung Ku Lee, Dae Wui Yoon, Si Woo Lee, Jong Yeol Kim, Jin Kwan Kim and Chol Shin
    Citation: BMC Complementary and Alternative Medicine 2015 15:399
  44. Macrofungi have an established history of use in traditional oriental medicine. Anthracophyllum lateritium is a terrestrial macrofungus found in the dry zone forest reserves in Sri Lanka. Yet there are no scienti...

    Authors: Dilusha M Fernando, Ravi LC Wijesundera, Preethi Soysa, Dilip de Silva and Chandrika M Nanayakkara
    Citation: BMC Complementary and Alternative Medicine 2015 15:398
  45. Cerebral ischemia and reperfusion (CIR) is a pathological condition characterized by a first blood supply restriction to brain followed by the consequent restoration of blood flow and simultaneous reoxygenation.

    Authors: Sabrina Giacoppo, Maria Galuppo, Gina Rosalinda De Nicola, Renato Iori, Placido Bramanti and Emanuela Mazzon
    Citation: BMC Complementary and Alternative Medicine 2015 15:397
  46. Juglans regia has been found to exhibit significant anticancer activity against various human cancer cell lines. This study was undertaken to isolate the active chemical constituent (Juglone) and to investigate i...

    Authors: Xue-Bang Zhang, Chang-Lin Zou, Yu-Xia Duan, Fang Wu and Gang Li
    Citation: BMC Complementary and Alternative Medicine 2015 15:396
  47. The root of Angelica dahurica Bentham et Hooker (Umbelliferae) has been used as a traditional medicine for colds, headache, dizziness, toothache, supraorbital pain, nasal congestion, acne, ulcer, carbuncle, and r...

    Authors: Kyungjin Lee, Min Sik Shin, Inhye Ham and Ho-Young Choi
    Citation: BMC Complementary and Alternative Medicine 2015 15:395
  48. Methylglyoxal (MG) is one of the most reactive glycating agents, which result the formation of advanced glycation end-products (AGEs) that have been implicated in the progression of age-related diseases. Inhib...

    Authors: Weerachat Sompong and Sirichai Adisakwattana
    Citation: BMC Complementary and Alternative Medicine 2015 15:394