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  1. Recent studies report that inflammatory diseases of the large intestine are associated with colorectal cancer. Geijigajakyak Decoction (GJD) has antispasmodic and anti-inflammatory effects on the gastrointestinal...

    Authors: Soong-in Lee, Jeong A Bae, Yoo-Seung Ko, Kyoung-in Lee, Hangun Kim and Kyung Keun Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:288
  2. Medicinal plants play great roles in the treatment of various infectious diseases. Rhamnus prinoides is one of the medicinal plants used traditionally for treatment of bacterial diseases. The antibacterial activi...

    Authors: Yalew Molla, Teshome Nedi, Getachew Tadesse, Haile Alemayehu and Workineh Shibeshi
    Citation: BMC Complementary and Alternative Medicine 2016 16:287
  3. Gigantol and syringic acid (SA) have been shown to synergistically prevent formation of diabetic cataract (DC). However, the exact mechanism of this effect is unknown. Here, we investigate the effect of these ...

    Authors: Jie Wu, Xue Li, Hua Fang, Yanqun Yi, Dan Chen, Yan Long, Xinxin Gao, Xiaoyong Wei and C-Y. Oliver Chen
    Citation: BMC Complementary and Alternative Medicine 2016 16:286
  4. Despite the increasing number and variety of antiepileptic drugs, nearly 30 % of epileptic patients who receive appropriate medical attention have persisting seizures. Anticonvulsant activity has been demonstr...

    Authors: Germain Sotoing Taiwe, Bernard Dabole, Thierry Bang Tchoya, Joseph Renaud Menanga, Paul Désiré Djomeni Dzeufiet and Michel De Waard
    Citation: BMC Complementary and Alternative Medicine 2016 16:285
  5. Acacia ataxacantha is a medicinal specie used extensively in traditional medicine of Benin republic to treat infectious diseases. Our previous study showed interesting antibacterial and antifungal activities agai...

    Authors: Abdou Madjid O. Amoussa, Latifou Lagnika, Mélanie Bourjot, Cathérine Vonthron-Senecheau and Ambaliou Sanni
    Citation: BMC Complementary and Alternative Medicine 2016 16:284
  6. The Bhutanese So-wa-rig-pa medicine (BSM) was integrated with the allopathic (modern) health care system in 1967. Ever since the health care integration policy was implemented, the BSM has gone through many phase...

    Authors: Phurpa Wangchuk and ᅟ Tashi
    Citation: BMC Complementary and Alternative Medicine 2016 16:283
  7. Diabetes is a growing burden in sub-Saharan Africa where traditional medicines (TMs) remain a primary form of healthcare in many settings. In Tanzania, TMs are frequently used to treat non-communicable disease...

    Authors: Joseph Lunyera, Daphne Wang, Venance Maro, Francis Karia, David Boyd, Justin Omolo, Uptal D. Patel and John W. Stanifer
    Citation: BMC Complementary and Alternative Medicine 2016 16:282
  8. Malignant mesothelioma is a locally aggressive and highly lethal neoplasm of pleural, peritoneal and pericardial mesothelial cells without successful therapy. Previously, we reported that Quercetin in combinat...

    Authors: Asuman Demiroglu-Zergeroglu, Emel Ergene, Nurettin Ayvali, Victor Kuete and Hulya Sivas
    Citation: BMC Complementary and Alternative Medicine 2016 16:281
  9. Nerium oleander L. (syn. Nerium indicum Mill, Nerium odorum Aiton) belongs to the family Apocynaceae. It is used for its anti-inflammatory, anti-diabetic, anti-cancer and hepatoprotect...

    Authors: Priyankar Dey, Somit Dutta, Anashuya Biswas-Raha, Mousumi Poddar Sarkar and Tapas Kumar Chaudhuri
    Citation: BMC Complementary and Alternative Medicine 2016 16:280
  10. Chronic pain can alter the autonomic balance with increased sympathetic activity reflected in altered heart rate variability (HRV). It has been proposed that yoga can be useful to correct the autonomic imbalan...

    Authors: Shirley Telles, Sachin Kumar Sharma, Ram Kumar Gupta, Abhishek Kumar Bhardwaj and Acharya Balkrishna
    Citation: BMC Complementary and Alternative Medicine 2016 16:279
  11. We have previously shown that the grape bioactive compound resveratrol (RSV) potentiates grape seed extract (GSE)-induced colon cancer cell apoptosis at physiologically relevant concentrations. However, RSV-GS...

    Authors: Lavanya Reddivari, Venkata Charepalli, Sridhar Radhakrishnan, Ramakrishna Vadde, Ryan J. Elias, Joshua D. Lambert and Jairam K. P. Vanamala
    Citation: BMC Complementary and Alternative Medicine 2016 16:278
  12. To identify a novel therapeutic agent for hepatocellular carcinoma (HCC), for which no promising therapeutic agent exists, we screened a panel of plants and found that Juniperus chinensis exhibited potential anti...

    Authors: Zong-Keng Kuo, Mei-Wei Lin, I-Huang Lu, Hsin-Jan Yao, Hsin-Chieh Wu, Chun-Chung Wang, Shyh-Horng Lin, Si-Yuan Wu, Tien-Soung Tong, Yi-Cheng Cheng, Jui-Hung Yen, Ching-Huai Ko, Shu-Jiau Chiou, I-Horng Pan and Hsiang-Wen Tseng
    Citation: BMC Complementary and Alternative Medicine 2016 16:277
  13. Diabetes mellitus is a metabolic disorder of epidemic proportion, projected to become the major cause of morbidity and mortality in the world in future. Despite extensive research in understanding this disease...

    Authors: Maqsood A. Siddiqui, Saima Rasheed, Quaiser Saquib, Abdulaziz A. Al-Khedhairy, Mansour S. Al-Said, Javed Musarrat and Muhammad Iqbal Choudhary
    Citation: BMC Complementary and Alternative Medicine 2016 16:276
  14. Hancornia speciosa Gomes (Apocynaceae), popularly known as “mangabeira,” has been used in folk medicine to treat inflammatory disorders, hypertension, dermatitis, diabetes, liver diseases and gastric disorders. A...

    Authors: Manoela Torres-Rêgo, Allanny Alves Furtado, Mariana Angélica Oliveira Bitencourt, Maira Conceição Jerônimo de Souza Lima, Rafael Caetano Lisbôa Castro de Andrade, Eduardo Pereira de Azevedo, Thaciane da Cunha Soares, José Carlos Tomaz, Norberto Peporine Lopes, Arnóbio Antônio da Silva-Júnior, Silvana Maria Zucolotto and Matheus de Freitas Fernandes-Pedrosa
    Citation: BMC Complementary and Alternative Medicine 2016 16:275
  15. Plasma free fatty acids (FFA) are involved in blood lipid metabolism as well as many health complications. The present study was conducted to evaluate the potential role of chlorogenic acid complex from green ...

    Authors: Sudeep H.V., Venkatakrishna K, Dipak Patel and Shyamprasad K
    Citation: BMC Complementary and Alternative Medicine 2016 16:274
  16. Medicinal plants have proven their importance as a valuable source of molecules with therapeutic potential. Monotheca buxifolia (Falc.) A. DC. (family: Sapotaceae) is traditionally used as a hematinic, laxative, ...

    Authors: Irfan Ullah, Jamshaid Ali Khan, Muhammad Shahid, Ajmal Khan, Achyut Adhikari, Peer Abdul Hannan, Ibrahim Javed, Faisal Shakeel and Umar Farooq
    Citation: BMC Complementary and Alternative Medicine 2016 16:273
  17. Till now many of medicinal plants having claimed therapeutic value traditionally are waiting scientific verification of their efficacy and safety. Accordingly this study is conducted to evaluate the antidiarrh...

    Authors: Eshetie Melese Birru, Assefa Belay Asrie, Getnet Mequanint Adinew and Asegedech Tsegaw
    Citation: BMC Complementary and Alternative Medicine 2016 16:272
  18. Decatropis bicolor (Zucc.)Radlk is a plant that has been traditionally used for the treatment of breast cancer in some communities of Mexico. So, the aim of this study was to determine...

    Authors: C. C. Estanislao Gómez, A. Aquino Carreño, D. G. Pérez Ishiwara, E. San Martín Martínez, J. Morales López, N. Pérez Hernández and M. C. Gómez García
    Citation: BMC Complementary and Alternative Medicine 2016 16:266
  19. Besides conventional anticancer therapy many breast cancer patients use complementary and alternative medicine (CAM) like the medicinal herb mistletoe (Viscum album L.). To gain more knowledge about possible herb...

    Authors: U. Weissenstein, M. Kunz, K. Urech, U. Regueiro and S. Baumgartner
    Citation: BMC Complementary and Alternative Medicine 2016 16:271
  20. Carrageenan is a sulfated polysaccharide that exists in red seaweeds recently shown to have anticancer properties. Previous findings show various effects of carrageenan suppressing tumor cell growth. One of th...

    Authors: Eka Sunarwidhi Prasedya, Masao Miyake, Daisuke Kobayashi and Akihiro Hazama
    Citation: BMC Complementary and Alternative Medicine 2016 16:270
  21. The purpose of this study is to investigate cardiovascular benefits of juices obtained from two commonly consumed fruits in Thailand, Pachyrhizus erosus, L. (yam bean) and Psidium guajava, L. (guava), by examinin...

    Authors: Thitiporn Thaptimthong, Thitima Kasemsuk, Nathawut Sibmooh and Supeenun Unchern
    Citation: BMC Complementary and Alternative Medicine 2016 16:269
  22. Alnus nitida (Spach) Endl. is traditionally used for inflammatory disorders. Diarylheptanoids constituents having diverse therapeutically importance including hepato-protective was reported in A. nitida. The aim ...

    Authors: Moniba Sajid, Muhammad Rashid Khan, Naseer Ali Shah, Sayed Afzal Shah, Hammad Ismail, Tahira Younis and Zartash Zahra
    Citation: BMC Complementary and Alternative Medicine 2016 16:268
  23. Cancer chemotherapy is still hampered by clinical failures due to multi-drug resistance (MDR) of tumor cells. In the present study, we have investigated the cytotoxicity of 20 methanol extracts from 10 medicin...

    Authors: Victor Kuete, Cedric F. Tchinda, Flora T. Mambe, Veronique P. Beng and Thomas Efferth
    Citation: BMC Complementary and Alternative Medicine 2016 16:267
  24. Cortex Phellodendri (C. Phellodendri), the dried trunk bark of Phellodendron amurense Ruprecht, has been known as a traditional herbal medicine, showing several bioactivities. However, antiviral activity of C. Ph...

    Authors: Jae-Hoon Kim, Prasanna Weeratunga, Myun Soo Kim, Chamilani Nikapitiya, Byeong-Hoon Lee, Md Bashir Uddin, Tae-Hwan Kim, Ji-Eun Yoon, Chung Park, Jin Yeul Ma, Hongik Kim and Jong-Soo Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:265
  25. The medical application of pomegranate fruits and its peel is attracted human beings. The aim of the present study was to evaluate the in vitro α-Glucosidase inhibition, antimicrobial, antioxidant property and...

    Authors: Kaliyan Barathikannan, Babu Venkatadri, Ameer Khusro, Naif Abdullah Al-Dhabi, Paul Agastian, Mariadhas Valan Arasu, Han Sung Choi and Young Ock Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:264
  26. The liver performs diverse functions that are essential for life. In the absence of reliable liver protective drugs, a large number of natural medicinal preparations are used for the treatment of liver disease...

    Authors: Ahmed Wahid, Ashraf N. Hamed, Heba M. Eltahir and Mekky M. Abouzied
    Citation: BMC Complementary and Alternative Medicine 2016 16:263
  27. Iron in the overloaded condition in liver promotes the overproduction of free radicals that lead to oxidative stress and ultimately hepatic damage. The present study was designed to evaluate the ameliorating p...

    Authors: Dipankar Chaudhuri, Nikhil Baban Ghate, Sourav Panja, Tapasree Basu, Anil Khushalrao Shendge and Nripendranath Mandal
    Citation: BMC Complementary and Alternative Medicine 2016 16:262
  28. The fermented leaves and stems of Cyclopia intermedia are used to brew honeybush tea, a herbal tea indigenous to South Africa. The aim of this study was to evaluate the protective effect of fermented honeybush ex...

    Authors: A-Rang Im, Sung Hum Yeon, Jung Seung Lee, Key An Um, Young -Joon Ahn and Sungwook Chae
    Citation: BMC Complementary and Alternative Medicine 2016 16:261
  29. The present study was in quested to study the effects of β-sitosterol on methyl nitrosourea (MNU) induced mammary gland carcinoma in albino wistar rats.

    Authors: Chetan Manral, Subhadeep Roy, Manjari Singh, Swetlana Gautam, Rajnish K. Yadav, Jitendra K Rawat, Uma Devi, Md Nazam Ansari, Abdulaziz S. Saeedan and Gaurav Kaithwas
    Citation: BMC Complementary and Alternative Medicine 2016 16:260
  30. The study aimed to evaluate the effects of Acacia honey (AH) on the migration, differentiation and healing properties of the cultured rabbit corneal fibroblasts.

    Authors: Norzana Abd Ghafar, Choy Ker-Woon, Chua Kien Hui, Yasmin Anum Mohd Yusof and Wan Zurinah Wan Ngah
    Citation: BMC Complementary and Alternative Medicine 2016 16:259
  31. Acacia hydaspica R. Parker, family leguminosae, is a medicinally important plant. Different plant parts are used in various ailments in folk medicine. The current study aimed at invest...

    Authors: Tayyaba Afsar, Suhail Razak, Muhammad Rashid Khan, Saadia Mawash, Ali Almajwal, Maria Shabir and Ihsan Ul Haq
    Citation: BMC Complementary and Alternative Medicine 2016 16:258
  32. Osteoarthritic knee (OA knee) is a common condition in the elderly. Exploration of non-invasive complementary therapies for OA knee is warranted given the limitations of pharmacologic therapies. Auriculotherap...

    Authors: Lorna K. P. Suen, Chao Hsing Yeh and Simon K. W. Yeung
    Citation: BMC Complementary and Alternative Medicine 2016 16:257

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2016 16:391

  33. Clausena excavata Burm.f. is a shrub traditionally used to treat cancer patients in Asia. The main bioactive chemical components of the plant are alkaloids and coumarins. In this study, we isolated clausenidin fr...

    Authors: Peter M. Waziri, Rasedee Abdullah, Swee Keong Yeap, Abdul Rahman Omar, Nur Kartinee Kassim, Ibrahim Malami, Chee Wun How, Imaobong Christopher Etti and Mary Ladidi Abu
    Citation: BMC Complementary and Alternative Medicine 2016 16:256
  34. Psoriasis is a chronically recurrent inflammatory skin disease, modern medicine could achieve good therapeutic effect, but these treatments led to recurrence of the psoriasis, more severe symptoms due to damag...

    Authors: Jian-an Wei, Ling Han, Chuan-jian Lu, Rui-zhi Zhao, Jing Sun, Yue Lu and Han-jie Lin
    Citation: BMC Complementary and Alternative Medicine 2016 16:255
  35. Obesity is increasing worldwide and weight-control strategies, including the consumption of plant food supplements (PFS), are proliferating. This article identifies the herbal ingredients in PFS consumed for w...

    Authors: Alicia Garcia-Alvarez, Raimon Mila-Villarroel, Lourdes Ribas-Barba, Bernadette Egan, Mihaela Badea, Franco M. Maggi, Maija Salmenhaara, Patrizia Restani and Lluis Serra-Majem
    Citation: BMC Complementary and Alternative Medicine 2016 16:254
  36. Kiom-18 is a novel composition of Cinnamomum cassia, Pinus densiflora, Curcuma longa and Glycyrrhiza glabra. Curcuma longa and Glycyrrhiza glabra, which are traditional medicines in Asia, have been reported to de...

    Authors: Jung-Jin Lee, Ji-Hye Lee, Won-Kyung Cho, Joo-Hui Han and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2016 16:253
  37. Rice bran is bioactive-rich and has proven health benefits for humans. Moreover, its source, the brown rice has antioxidant, hypolipidemic and other functional properties that are increasingly making it a nutr...

    Authors: Wai-Teng Wong, Maznah Ismail, Mustapha Umar Imam and Yi-Da Zhang
    Citation: BMC Complementary and Alternative Medicine 2016 16:252
  38. Viscum album has shown inhibitory effect on different smooth muscles but underlying mechanisms in gut and vascular smooth muscles are not well defined. Additionally, the plant has also...

    Authors: Taous Khan, Sayyad Ali, Rahila Qayyum, Izhar Hussain, Fazli Wahid and Abdul Jabbar Shah
    Citation: BMC Complementary and Alternative Medicine 2016 16:251
  39. Cardiovascular diseases are a main cause of mortality worldwide. Spa bathing and immersion in thermoneutral water (ITW) have a long history in the treatment of cardiovascular risk factors.

    Authors: Johannes Naumann, Catharina Sadaghiani, Nina Bureau, Stefan Schmidt and Roman Huber
    Citation: BMC Complementary and Alternative Medicine 2016 16:250
  40. Bacopa monnieri is a medicinal plant which has long been used in Ayurvedic medicines to augment brain function and to improve memory. The purpose of our study was to identify and evalu...

    Authors: Seewaboon Sireeratawong, Kanjana Jaijoy, Parirat Khonsung, Nirush Lertprasertsuk and Kornkanok Ingkaninan
    Citation: BMC Complementary and Alternative Medicine 2016 16:249
  41. It is estimated that over half of the adult U.S. population currently has one or more chronic conditions, resulting in up to an estimated $1,600 in productivity loss annually for each employee with chronic dis...

    Authors: Jennifer Mongiovi, Zaixing Shi and Heather Greenlee
    Citation: BMC Complementary and Alternative Medicine 2016 16:248
  42. Callistemon citrinus (Curtis.) (Family- Myrtaceae) is a popular evergreen shrub in Bangladesh. In the present study, the leaves of this plant have been assessed comprehensively for fre...

    Authors: Farhana Ahmed and Mohammad Sharifur Rahman
    Citation: BMC Complementary and Alternative Medicine 2016 16:247
  43. Tangshen Formula (TSF) is a traditional Chinese medicine for the treatment of diabetic kidney disease (DKD). Liver-type fatty acid binding protein (L-FABP) is expressed in various tissues, including the kidney...

    Authors: Xin Yang, Bingxuan Zhang, Xiaoguang Lu, Meihua Yan, Yumin Wen, Tingting Zhao and Ping Li
    Citation: BMC Complementary and Alternative Medicine 2016 16:246
  44. Cedrus deodara is one of the traditional Chinese medicinal herbs that exhibits a line of biological activities. The current study extracted the total flavonoids from the pine needles of Cedrus deodara (TFPNCD), a...

    Authors: Xiaofeng Shi, Dongyan Liu, Junmin Zhang, Pengbin Hu, Wei Shen, Bin Fan, Quhuan Ma and Xindi Wang
    Citation: BMC Complementary and Alternative Medicine 2016 16:245
  45. The medicinal plants Vincetoxicum arnottianum (VSM), Berberis orthobotrys (BORM), Onosma hispida (OHRM and OHAM) and Caccinia macranthera (CMM) are used traditionally in Pakistan and around the world for the trea...

    Authors: Nadja Engel, Iftikhar Ali, Anna Adamus, Marcus Frank, Akber Dad, Sajjad Ali, Barbara Nebe, Muhammad Atif, Muhammad Ismail, Peter Langer and Viqar Uddin Ahmad
    Citation: BMC Complementary and Alternative Medicine 2016 16:244
  46. Red pitaya (Hylocereus polyrhizus) or known as buah naga merah in Malay belongs to the cactus family, Cactaceae. Red pitaya has been shown to give protection against liver damage and may reduce the stiffness of t...

    Authors: Nurul Shazini Ramli, Patimah Ismail and Asmah Rahmat
    Citation: BMC Complementary and Alternative Medicine 2016 16:243
  47. Present study has been conducted to know the anthelmintic activity of polyaniline coated silver nanoparticles (AgNPs) synthesized from Momordica charantia fruit extract.

    Authors: Md. Mamun Or Rashid, Jannatul Ferdous, Sujan Banik, Md. Rabiul Islam, A.H.M. Mazbah Uddin and Fataha Nur Robel
    Citation: BMC Complementary and Alternative Medicine 2016 16:242
  48. We previously demonstrated oxymatrine, an alkaloid from the Chinese medicine radix Sophorae flavescentis, ameliorates hemodynamic disturbances and cardiac fibrosis; however, the underlying mechanisms are unclear....

    Authors: Lingyun Fu, Yini Xu, Ling Tu, Haifeng Huang, Yanyan Zhang, Yan Chen, Ling Tao and Xiangchun Shen
    Citation: BMC Complementary and Alternative Medicine 2016 16:241
  49. Pain, the most common reasons for physician consultation, is a major symptom in many medical conditions that can significantly interfere with a person’s life quality and general functioning. Almost all painkil...

    Authors: Yuh-Fung Chen, Ming-Ming Lee, Hsun-Lang Fang, Jhao-Guei Yang, Yu-Chien Chen and Huei-Yann Tsai
    Citation: BMC Complementary and Alternative Medicine 2016 16:240
  50. In bone metabolism, Ca2+ disturbance and oxidative damage are the main biochemical factors related to pathology. Osteoblasts are bone-forming cells that also control bone endocrinology. Endocrine hormones and pro...

    Authors: Hwa-Young Lee, Hyung-Ryong Kim, Sun-Young Park, Han-Jung Chae and Jong-Hyun Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:237