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  1. Infectious diseases due to multidrug-resistant bacteria are one of the causes of treatment failures contributing to an increase in mortality and/or morbidity. In this study, we evaluated the antibacterial pote...

    Authors: Igor K. Voukeng, Veronique P. Beng and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2016 16:388
  2. Gliomas are highly aggressive tumors of the nervous system, and current treatments fail to improve patient survival. To identify substances that can be used as treatments for gliomas, we examined the effect of Ce...

    Authors: Hao Gu, Jun Feng, Haibo Wang, Yayun Qian, Lin Yang, Jue Chen, Feng Jin, Youyang Shi, Songhua Lu and Yangqing Liu
    Citation: BMC Complementary and Alternative Medicine 2016 16:387
  3. Wound healing is often impaired in diabetic animals and humans. Matrix metalloproteases act as pro-inflammatory agents in physiological wound healing pathways by stimulating cytokines including the interleukin...

    Authors: Hamid Galehdari, Samira Negahdari, Mahnaz Kesmati, Anahita Rezaie and Gholamreza Shariati
    Citation: BMC Complementary and Alternative Medicine 2016 16:386
  4. The Rubiaceae family has played a significant role in drug discovery by providing molecules with potential use as templates for the development of therapeutic drugs. This study was designed to study the in vit...

    Authors: Abimbola O. Aro, Jean P. Dzoyem, Jacobus N. Eloff and Lyndy J. McGaw
    Citation: BMC Complementary and Alternative Medicine 2016 16:385
  5. Natural products are valuable sources for anticancer agents. In the present study, methylferulate (MF) was identified for the first time from Tamarix aucheriana. Spectral data were used for identification of MF. ...

    Authors: Mohamed Salah I. Abaza, Mohammad Afzal, Raja’a J. Al-Attiyah and Radhika Guleri
    Citation: BMC Complementary and Alternative Medicine 2016 16:384
  6. As a member of non-coding RNAs family, long non-coding RNAs’ functions in cancer needs to be further investigated. It has been indicated that the functions of Hox transcript antisense intergenic RNA (lncRNA: H...

    Authors: Ting Ma, Rui-ping Wang and Xi Zou
    Citation: BMC Complementary and Alternative Medicine 2016 16:383
  7. Herbal materials should be stored at optimal conditions in order to retain their nutritional quality. Proper storage has a significant impact on the quality of the herbs and spices.

    Authors: Ali Ghasemzadeh, Hawa Z. E. Jaafar and Asmah Rahmat
    Citation: BMC Complementary and Alternative Medicine 2016 16:382
  8. Advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) arise as a result of excessive glycation and oxidation processes of proteins in hyperglycemia and oxidative stress conditions...

    Authors: Ewa Grzebyk and Agnieszka Piwowar
    Citation: BMC Complementary and Alternative Medicine 2016 16:381
  9. The extracellular signal-regulated kinase (ERK) signaling pathway is considered to be associated with the pathogenesis and treatment of depression. Acupuncture has been demonstrated to ameliorate depression-re...

    Authors: Xuhui Zhang, Yingzhou Song, Tuya Bao, Miao Yu, Mingmin Xu, Yu Guo, Yu Wang, Chuntao Zhang and Bingcong Zhao
    Citation: BMC Complementary and Alternative Medicine 2016 16:380
  10. Traditional healers in Ethiopia use a wide range of medicinal plants with antidiarrheal properties. Among these, Croton macrostachyus is one such plant claimed to have an antidiarrheal activity in Ethiopian folkl...

    Authors: Amsalu Degu, Ephrem Engidawork and Workineh Shibeshi
    Citation: BMC Complementary and Alternative Medicine 2016 16:379
  11. Natural products have being used as potential inhibitors against carbohydrate-hydrolyzing enzymes to treat diabetes mellitus. Chinese dark tea has various interesting bioactivities. In this study, the active c...

    Authors: Shuyuan Liu, Zhi Yu, Hongkai Zhu, Wei Zhang and Yuqiong Chen
    Citation: BMC Complementary and Alternative Medicine 2016 16:378
  12. Allium sativum L. (A.S.) “garlic”, one of the most interesting medicinal plants, has been suggested to contain compounds that could be beneficial in numerous pathological situations including cancer. In this work...

    Authors: Mouna Moutia, Fouad Seghrouchni, Omar Abouelazz, Anass Elouaddari, Abdellah Al Jahid, Abdelhalim Elhou, Sellama Nadifi, Jamal Jamal Eddine, Norddine Habti and Abdallah Badou
    Citation: BMC Complementary and Alternative Medicine 2016 16:377
  13. Hydrogen peroxide is continuously generated in living cells through metabolic pathways and serves as a source of reactive oxygen species. Beyond the threshold level, it damages cells and causes several human d...

    Authors: A. D. Naveen Kumar, Ganesh Babu Bevara, Laxmi Koteswaramma Kaja, Anil Kumar Badana and Rama Rao Malla
    Citation: BMC Complementary and Alternative Medicine 2016 16:376
  14. Ajuga bracteosa has been extensively used traditionally for the treatment of a variety of diseases. The aim of the study was to scientifically validate the wide-scale exploitation of A. bracteosa in folk medicine...

    Authors: Waqas Khan Kayani, Erum Dilshad, Tanveer Ahmed, Hammad Ismail and Bushra Mirza
    Citation: BMC Complementary and Alternative Medicine 2016 16:375
  15. Indonesian mistletoe grows on various trees. Mango Mistletoes (Dendrophthoe pentandra) is one type of mistletoe that grown on mango tree (.benalu mangga in bahasa Indonesia). Our study used mistletoe as a parasit...

    Authors: Agustina Tri Endharti, Adisti Wulandari, Anik Listyana, Eviana Norahmawati and Sofy Permana
    Citation: BMC Complementary and Alternative Medicine 2016 16:374
  16. Psoralea Fructus (PF), the dried and ripe fruit of Psoralea corylifolia exhibits an anti-cancer activity. However, the molecular mechanisms by which PF inhibits the proliferation of cancer cells have not been elu...

    Authors: Gwang Hun Park, Ji Ho Sung, Hun Min Song and Jin Boo Jeong
    Citation: BMC Complementary and Alternative Medicine 2016 16:373
  17. Medications from Anthroposophical Medicine (AM) are clinically used for the treatment of infections within a whole medical system but have not yet been evaluated regarding antibacterial effects. The aims of th...

    Authors: Eva Roser, Carsten Gründemann, Inge Engels and Roman Huber
    Citation: BMC Complementary and Alternative Medicine 2016 16:372
  18. Blood-stasis syndrome (BSS) is one of the Traditional Chinese medicine (TCM) syndrome differentiations that are commonly seen in stroke and ischemic heart diseases; however, the BSS differentiation criterion i...

    Authors: Jiangquan Liao, Yongmei Liu and Jie Wang
    Citation: BMC Complementary and Alternative Medicine 2016 16:371

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2016 16:458

  19. Melandrii Herba, a medicinal plant, has been used in Korea for treatment of bacterial and fungal infection. However, the safety and toxicity of Melandrii Herba have not yet been established. Therefore, we inve...

    Authors: Eunsook Park, Mee-Young Lee, Chang-Seob Seo, Sae-Rom Yoo, Woo-Young Jeon and Hyeun-Kyoo Shin
    Citation: BMC Complementary and Alternative Medicine 2016 16:370
  20. Shenghui soup is a traditional Chinese herbal medicine used in clinic for the treatment of forgetfulness. In order to understanding the prescription principle, the effects of “tonifying qi and strengthening splee...

    Authors: Qi Zhang, Zi-Jian Zhang, Xing-Hua Wang, Jie Ma, Yue-Han Song, Mi Liang, Sen-Xiang Lin, Jie Zhao, Ao-Zhe Zhang, Feng Li and Qian Hua
    Citation: BMC Complementary and Alternative Medicine 2016 16:369
  21. Clinacanthus nutans (Burm. f.) Lindau leaves are widely used by cancer patients and the leaf extracts possess cytotoxic and antiproliferative effects on several human cancer cell lines. However, the effect of C. ...

    Authors: Siat Yee Fong, Terrence Piva, Chaitali Dekiwadia, Sylvia Urban and Tien Huynh
    Citation: BMC Complementary and Alternative Medicine 2016 16:368
  22. Propolis and Hypericum perforatum L. are natural products which contain many active compounds and have numerous beneficial effects, including an antitumor effect. Gliobmastoma multiforme (GBM) is a common primary...

    Authors: Maria H. Borawska, Sylwia K. Naliwajko, Justyna Moskwa, Renata Markiewicz-Żukowska, Anna Puścion-Jakubik and Jolanta Soroczyńska
    Citation: BMC Complementary and Alternative Medicine 2016 16:367
  23. Sutherlandia frutescens (L) R.Br. is one of traditional herbal medicines that formed the basis of primary health care systems since the earliest days and is still widely used. Sutherla...

    Authors: Peter Masoko, Itumeleng H. Mabusa and Rachmond L. Howard
    Citation: BMC Complementary and Alternative Medicine 2016 16:366
  24. Mineral based preparations are widely used for centuries as antimicrobial agents. However, the efficacy and the mode of action of mineral based preparations are uncertain due to the insufficient antimicrobial ...

    Authors: A. U. Wijenayake, C. L. Abayasekara, H. M. T. G. A. Pitawala and B. M. R. Bandara
    Citation: BMC Complementary and Alternative Medicine 2016 16:365
  25. Cancer stem cells (CSCs) are considered as the origin of tumor relapse. Here, we investigated the effects of Fructus Viticis total flavonoids (FVTF) on the characteristics of lung cancer stem-like cells (LCSLC...

    Authors: Xiaocheng Cao, Hui Zou, Jianguo Cao, Yinghong Cui, Shuwen Sun, Kaiqun Ren, Zhenwei Song, Duo Li and Meifang Quan
    Citation: BMC Complementary Medicine and Therapies 2016 16:364
  26. Court-type Thai traditional massage (CTTM) has specific major signal points (MaSP) for treating musculoskeletal conditions. The objectives of this study are to investigate the anatomical surfaces and structure...

    Authors: Vasana Plakornkul, Manmas Vannabhum, Yadaridee Viravud, Jantima Roongruangchai, Pramook Mutirangura, Pravit Akarasereenont and Tawee Laohapand
    Citation: BMC Complementary and Alternative Medicine 2016 16:363
  27. African Trypanosomiasis is a neglected tropical disease with a large impact on the livelihood of the rural poor in Sub-Saharan Africa. The available drugs for managing this disease are old, expensive and are f...

    Authors: Ermias Mergia, Workineh Shibeshi, Getachew Terefe and Tilahun Teklehaymanot
    Citation: BMC Complementary and Alternative Medicine 2016 16:362
  28. Cerebral infarction frequently leads to mild cognitive impairment (MCI). Prompt management of MCI can prevent vascular dementia and improve patient outcome. This single center randomized controlled trial aims ...

    Authors: Shuhua Wang, Hongling Yang, Jie Zhang, Bin Zhang, Tao Liu, Lu Gan and Jiangang Zheng
    Citation: BMC Complementary and Alternative Medicine 2016 16:361
  29. Chronic obstructive pulmonary disease (COPD) is a major public health problem and gives arise to severe chronic morbidity and mortality in the world. Inflammatory response and oxidative stress play dominant ro...

    Authors: Ming-Xing Zhou, Xuan Wei, Ai-Ling Li, Ai-Min Wang, Ling-Zi Lu, Yue Yang, Dong-Mei Ren, Xiao-Ning Wang, Xue-Sen Wen, Hong-Xiang Lou and Tao Shen
    Citation: BMC Complementary and Alternative Medicine 2016 16:360
  30. Exaggerated vasoconstriction plays a very important role in the hypertension, a major component of metabolic syndrome (MetS). In the current work, the potential protective effect of methanol extract of fruit h...

    Authors: Hossam M. Abdallah, Hany M. El-Bassossy, Gamal A. Mohamed, Ali M. El-halawany, Khalid Z. Alshali and Zainy M. Banjar
    Citation: BMC Complementary and Alternative Medicine 2016 16:359
  31. Co-products obtained from pomegranate juice processing contain high levels of polyphenols with potential high added values. From value-addition viewpoint, the aim of this study was to evaluate the stability of...

    Authors: Olaniyi Amos Fawole and Umezuruike Linus Opara
    Citation: BMC Complementary and Alternative Medicine 2016 16:358
  32. Current malaria treatment is either “anti-parasitic”, “anti-infectivity” or both without addressing the pathophysiological derangement (anti-disease aspect) associated with the disease. Asiatic acid is a natur...

    Authors: G. A. Mavondo, B. N. Mkhwananzi, M. V. Mabandla and C. T. Musabayane
    Citation: BMC Complementary and Alternative Medicine 2016 16:357
  33. The primary objective of this study was to assess whether Zhengtian Capsule was non-inferior to flunarizine in efficacy and safety profile for prevention of migraine in adults.

    Authors: Kegang Cao, Fang Han, Anji Lin, Wenming Yang, Jianjun Zhao, Hui Zhang, Yanbing Ding, Wei Xie, Yinping Xu, Tingmin Yu, Xinzhi Wang, Xiaosu Yang, Jiying Zhou, Qun Hou, Lihua Yu and Ying Gao
    Citation: BMC Complementary and Alternative Medicine 2016 16:356
  34. KBH-1 is an herbal mixture of Saururus chinensis, Curcuma longa and Polygala tenuifolia. Each herb has been reported to have various pharmaceutical activities; however, the synergistic effect of this herbal compo...

    Authors: Ji-Hye Lee, Jung-Jin Lee, Won-Kyung Cho, Nam-Hui Yim, Hyun-Kyu Kim, Bora Yun and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2016 16:355
  35. Several compounds isolated from Dryobalanops have been reported to exhibit cytotoxic effects to several cancer cell lines. This study investigated the cytotoxic effects, cell cycle arrest and mode of cell death i...

    Authors: Napsiah Abd Rahman, Latifah Saiful Yazan, Agustono Wibowo, Norizan Ahmat, Jhi Biau Foo, Yin Sim Tor, Swee Kong Yeap, Zainal Abidin Razali, Yong Sze Ong and Sharida Fakurazi
    Citation: BMC Complementary and Alternative Medicine 2016 16:354
  36. Communication between different health care providers (conventional and complementary) and cancer patients about their use of complementary therapies affects the health and safety of the patients. The aim of t...

    Authors: Trine Stub, Sara A. Quandt, Thomas A. Arcury, Joanne C. Sandberg, Agnete E. Kristoffersen, Frauke Musial and Anita Salamonsen
    Citation: BMC Complementary and Alternative Medicine 2016 16:353
  37. Do In Seung Gi-Tang (DISGT) is an herbal mixture of traditional Korean medicine that is composed of Rheum undulatum Linne, Prunus Persica (L.) Batsch, Conyza canadensis L., Cinnamomum Cassia Presl, and Glycytthiz...

    Authors: Sun Haeng Park, Yoon-Young Sung, Seol Jang, Kyoung Jin Nho, Go Ya Choi and Ho Kyoung Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:352
  38. Consumption of plant-derived nutraceuticals and crude drugs in traditional medicine is widely believed to confer beneficial effects in thwarting the progression of cardiovascular diseases. Rhus tripartita (family...

    Authors: Abdelaaty A. Shahat, Mansour S. Alsaid, Syed Rafatullah, Mohammed O. Al-Sohaibani, Mohammad K. Parvez, Mohammed S. Al-Dosari, Vassiliki Exarchou and Luc Pieters
    Citation: BMC Complementary and Alternative Medicine 2016 16:351
  39. Consumption of virgin olive oil (VOO) has been associated with a low breast cancer incidence. Pinoresinol is a phytoestrogen that is typically found in VOO. Considering the role of oestrogen in breast cancer d...

    Authors: Alicia López-Biedma, Cristina Sánchez-Quesada, Gabriel Beltrán, Miguel Delgado-Rodríguez and José J. Gaforio
    Citation: BMC Complementary and Alternative Medicine 2016 16:350
  40. Chinese traditional “eye exercises of acupoints” have been advocated as a compulsory measure to reduce visual symptoms, as well as to retard the development of refractive error, among Chinese students for deca...

    Authors: Zhong Lin, Balamurali Vasudevan, Su Jie Fang, Vishal Jhanji, Guang Yun Mao, Wei Han, Tie Ying Gao, Kenneth J. Ciuffreda and Yuan Bo Liang
    Citation: BMC Complementary and Alternative Medicine 2016 16:349
  41. Unsweetened natural cocoa has antimalarial properties. Unsweetened natural cocoa powder (UNCP), obtained as a result of the removal of cocoa butter from a cocoa bean protects against malaria episodes. Cocoa po...

    Authors: Isaac Julius Asiedu-Gyekye, Mahmood Abdulai Seidu, Banga Benoit N’guessan, Samuel Frimpong–Manso, Joseph Edusei Sarkodie, Samuel Adjei, Schevadnazy Kutu, Joseph Osei-Little, Alexander Kwadwo Nyarko and Philip Debrah
    Citation: BMC Complementary and Alternative Medicine 2016 16:348
  42. Sanguisorbae Radix (SR) is a well-known herbal medicine used to treat inflammatory disease and skin burns in Asia. In addition, it is used to treat many types of allergic skin diseases, including urticaria, ec...

    Authors: Ju-Hye Yang, Jae-Myung Yoo, Won-Kyung Cho and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2016 16:347
  43. Bupleuri Radix (in Chinese Chaihu), the dried roots of Bupleurum Chinense DC, is a traditional Chinese medicine widely used to treat fever, hepatitis, jaundice, nephritis, dizziness. When baked with vinegar, its ...

    Authors: Ya Zhao, Yin-Jie Wang, Rui-Zhi Zhao and Fei-Jun Xiang
    Citation: BMC Complementary and Alternative Medicine 2016 16:346
  44. Proanthocyanidins belong to a class of polyphenolic compounds called flavonoids and have been reported to exhibit important biological activities. The immature inflorescence of Cocos nucifera L. is used by Ayurve...

    Authors: Chayanika Padumadasa, Durga Dharmadana, Ajit Abeysekera and Mayuri Thammitiyagodage
    Citation: BMC Complementary and Alternative Medicine 2016 16:345
  45. Incarvillea compacta Maxim. has been used to treat stomach disease in Tibet for many years. The objectives of this study were to explore the anti-cancer ability of trichloromethane fraction of I. compacta Maxim. ...

    Authors: Lijing Zhang, Haifeng Wu, Guibo Sun, Xudong Xu, Xiaobo Sun and Li Cao
    Citation: BMC Complementary and Alternative Medicine 2016 16:344
  46. We aimed to evaluate the effect of an 8-week yoga intervention on the shoulder and spinal actions of women with breast cancer-related arm lymphoedema.

    Authors: Annette Loudon, Tony Barnett, Neil Piller, Maarten A. Immink, Denis Visentin and Andrew D. Williams
    Citation: BMC Complementary and Alternative Medicine 2016 16:343
  47. Current clinical practices used to functionally classify heart failure (HF) are time-consuming, expensive, or require complex calculations. This study aimed to design an inquiry list from the perspective of tr...

    Authors: Tieh-Cheng Fu, Yi-Chung Lin, Ching-Mao Chang, Wei-Ling Chou, Pei-Hsun Yuan, Min-Hui Liu, Chao-Hung Wang, Juei-Chao Chen, Hen-Hong Chang and Tai-Long Pan
    Citation: BMC Complementary and Alternative Medicine 2016 16:342
  48. Calibrachoa x hybrida (Solanaceae) cultivars are widely used in North and South America as ornamental plants. Their potential as a source of antimicrobial compounds might be enhanced by seaweed extract (SWE) appl...

    Authors: Hosam O. Elansary, Jeff Norrie, Hayssam M. Ali, Mohamed Z. M. Salem, Eman A. Mahmoud and Kowiyou Yessoufou
    Citation: BMC Complementary and Alternative Medicine 2016 16:341
  49. We developed and disseminated an educational DVD to introduce U.S. Veterans to independently-practiced complementary and alternative medicine (CAM) techniques and encourage CAM experimentation. The project’s g...

    Authors: Rachel Forster Held, Susan Santos, Michelle Marki and Drew Helmer
    Citation: BMC Complementary and Alternative Medicine 2016 16:340
  50. Chronic hyperglycemia enhances the formation of advanced glycation endproducts (AGEs) and reactive oxygen species (ROS), contributing to diabetic complications. Thus, controlling blood glucose levels, inhibiti...

    Authors: Emily R. Koch and Permal Deo
    Citation: BMC Complementary and Alternative Medicine 2016 16:338