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  1. To achieve effective antiretroviral therapy (ART) outcomes, adherence to an antiretroviral regimen and a good immunometabolic response are essential. Food insecurity can act as a real barrier to adherence to b...

    Authors: Koy Tshingani, Philippe Donnen, Henri Mukumbi, Pierre Duez and Michèle Dramaix-Wilmet
    Citation: BMC Complementary and Alternative Medicine 2017 17:420
    Content type: Research article Published on:

  2. Hepatocellular carcinoma (HCC) accounts for major cancer-related deaths despite current advanced therapies. Treatment and prognosis of HCC is better in patients with preserved liver function. Many natural prod...

    Authors: Fazal Khan, Tariq Jamal Khan, Gauthaman Kalamegam, Peter Natesan Pushparaj, Adeel Chaudhary, Adel Abuzenadah, Taha Kumosani, Elie Barbour and Mohammed Al-Qahtani
    Citation: BMC Complementary and Alternative Medicine 2017 17:418
    Content type: Research article Published on:

  3. The purpose of the present study was to examine the body composition of So-Yang type males according to Sasang constitutional medicine, which is popular in Korea. Different Sasang constitutional types are asso...

    Authors: Jiwon Yoon, Jiho Nam, Chae Hun Leem and Jong Yeol Kim
    Citation: BMC Complementary and Alternative Medicine 2017 17:417
    Content type: Research article Published on:

  4. Extracts from perna canaliculus, the Green Lipped Mussel (GLM) are widely used as a complimentary therapy by patients with osteoarthritis (OA). The current study investigated the potential of a novel GLM formulat...

    Authors: Simon Stebbings, Andrew Gray, Anthony G. Schneiders and Andrew Sansom
    Citation: BMC Complementary and Alternative Medicine 2017 17:416
    Content type: Research article Published on:

  5. Acorus gramineus has been reported to exhibit various pharmacological effects including inhibition of cholesterol synthesis, enhancement of lipid metabolism, prevention of dementia and...

    Authors: Joo-Myung Moon, Hae-Mi Sung, Hyun-Jung Jung, Jae-Won Seo and Ji-Hyang Wee
    Citation: BMC Complementary and Alternative Medicine 2017 17:414
    Content type: Research article Published on:

  6. Kangfuxin (KFX) is the ethanol extract of Periplaneta americana L, which has been widely used in the Traditional Chinese Medicine for the repair and regeneration of injured organ and tissues with long history. Th...

    Authors: Yan-Fen Huang, Long-Jian Li, Si-Qian Gao, Yang Chu, Jie Niu, Fu-Neng Geng, Yong-Mei Shen and Li-Hua Peng
    Citation: BMC Complementary and Alternative Medicine 2017 17:413
    Content type: Research article Published on:

  7. Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is widely used in Southeast Asia, China and India in food preparation and for medicinal purposes. Meanwhile, the neuroprotective ...

    Authors: Xin-Shi Wang, Zeng-Rui Zhang, Man-Man Zhang, Miao-Xuan Sun, Wen-Wen Wang and Cheng-Long Xie
    Citation: BMC Complementary and Alternative Medicine 2017 17:412
    Content type: Research article Published on:

  8. The increase in demand and consumption of single clove garlic or ‘Solo garlic’ (Allium sativum) has resulted in an increase in research on its therapeutic properties. The present study aims to evaluate the antiox...

    Authors: Khalid Mohammed Naji, Elham Shukri Al-Shaibani, Fatima A. Alhadi, Safa’a Abdulrzaq Al-Soudi and Myrene R. D’souza
    Citation: BMC Complementary and Alternative Medicine 2017 17:411
    Content type: Research article Published on:

  9. Intestinal injury is a potential cause of death after high-dose radiation exposure. The aim of the present study was to investigate the protective effects of resveratrol against radiation-induced small intesti...

    Authors: Heng Zhang, Hao Yan, Xiaoliang Zhou, Huaqing Wang, Yiling Yang, Junling Zhang and Hui Wang
    Citation: BMC Complementary and Alternative Medicine 2017 17:410
    Content type: Research article Published on:

  10. Shinrin-yoku (experiencing the forest atmosphere or forest bathing) has received increasing attention from the perspective of preventive medicine in recent years. Some studies have rep...

    Authors: Yuki Ideno, Kunihiko Hayashi, Yukina Abe, Kayo Ueda, Hiroyasu Iso, Mitsuhiko Noda, Jung-Su Lee and Shosuke Suzuki
    Citation: BMC Complementary and Alternative Medicine 2017 17:409
    Content type: Research article Published on:

  11. The public safety of α-tocopherol has been called in question by several meta-analyses which have raised concern among regulatory authorities. The objective of this study was to evaluate the Cochrane Database ...

    Authors: Christopher J. Oliver and Stephen P. Myers
    Citation: BMC Complementary and Alternative Medicine 2017 17:408
    Content type: Correspondence Published on:

  12. Trema orientalis (T. orientalis Linn) has been used in the management of malaria in the western part of Nigeria and despite its application in ethnomedicine, there is dearth of scienti...

    Authors: John Oludele Olanlokun, Oluwole Moses David and Anthony Jide Afolayan
    Citation: BMC Complementary and Alternative Medicine 2017 17:407
    Content type: Research article Published on:

  13. Electroacupuncture (EA) has been applied to treat and prevent diseases for years. However, molecular events happened in both the acupunctured site and the internal organs after EA stimulation have not been cla...

    Authors: Jing-Shan Wu, Hsin-Yi Lo, Chia-Cheng Li, Feng-Yuan Chen, Chien-Yun Hsiang and Tin-Yun Ho
    Citation: BMC Complementary and Alternative Medicine 2017 17:406
    Content type: Research article Published on:

  14. Holarrhena antidysenterica has been employed as an ethnobotanical plant for the treatment of dysentery, diarrhoea, fever, and bacterial infections. Biological activities of the princip...

    Authors: Thanyaluck Siriyong, Potjanee Srimanote, Sasitorn Chusri, Boon-ek Yingyongnarongkul, Channarong Suaisom, Varomyalin Tipmanee and Supayang Piyawan Voravuthikunchai
    Citation: BMC Complementary and Alternative Medicine 2017 17:405
    Content type: Research article Published on:

  15. Onchocerciasis is one of the tropical neglected diseases (NTDs) caused by the nematode Onchocerca volvulus. Control strategies currently in use rely on mass administration of ivermectin, which has marked activity...

    Authors: Justin Kalmobé, Dieudonné Ndjonka, Djafsia Boursou, Jacqueline Dikti Vildina and Eva Liebau
    Citation: BMC Complementary and Alternative Medicine 2017 17:404
    Content type: Research article Published on:

  16. Hyperlipidaemia is the major risk factor contributing to the development and progression of atherosclerosis, fatty liver and cerebrovascular disease. Pleurotus eryngii (P. eryngii) is rich in biologically active ...

    Authors: Chen Zhang, Juan Li, Jing Wang, Xingling Song, Jianjun Zhang, Shang Wu, Chunlong Hu, Zhiyuan Gong and Le Jia
    Citation: BMC Complementary and Alternative Medicine 2017 17:403
    Content type: Research article Published on:

  17. Studies of the effects of electromagnetic fields (EMFs) on cartilaginous cells show a broad range of outcomes. However EMFs are not yet clinically applied as standard treatment of osteoarthritis, as EMF effect...

    Authors: Julia Isabelle Redeker, Bärbel Schmitt, Nele Pascale Grigull, Christian Braun, Andreas Büttner, Volkmar Jansson and Susanne Mayer-Wagner
    Citation: BMC Complementary and Alternative Medicine 2017 17:402
    Content type: Research article Published on:

  18. Our previous study demonstrated that an up-regulation of the Brain-Derived Neurotrophic Factor (BDNF) signaling pathway is involved the mechanism causing the recurrence of triple negative breast cancer. The ai...

    Authors: Jen-Hwey Chiu, Fang-Pey Chen, Yi-Fang Tsai, Man-Ting Lin, Ling-Ming Tseng and Yi-Ming Shyr
    Citation: BMC Complementary and Alternative Medicine 2017 17:401
    Content type: Research article Published on:

  19. The resistance of some medico-veterinary parasite strains as well as the unavailability and toxicity of synthetic anthelminthics on humans, animals and the impacts of their residues in the environment have pus...

    Authors: Sergine Errole Ngouateu Teufack, Gertrude NMbogning Tayo, Marc Ngangout Alidou, Jeannette Yondo, Amely Frankline Djiomene, Josué Wabo Poné and Faùily Mpoame Mbida
    Citation: BMC Complementary and Alternative Medicine 2017 17:400
    Content type: Research article Published on:

  20. The common usage of chewing sticks prepared from Neem tree (Azadirachta indica) in India suggests its potential efficacy in periodontal diseases. The objective of this study is to explore the antibacterial effect...

    Authors: Leali Heyman, Yael Houri-Haddad, Samuel N. Heyman, Isaac Ginsburg, Yossi Gleitman and Osnat Feuerstein
    Citation: BMC Complementary and Alternative Medicine 2017 17:399
    Content type: Research article Published on:

  21. Cardiovascular disease (CVD) is the leading cause of premature death throughout the world. An estimated 17.5 million people died from CVD in 2012, representing 31% of all global deaths. Nardostachys chinensis (NC...

    Authors: Min Li, Xue Xu, Xinyu Yang, Joey S. W. Kwong and Hongcai Shang
    Citation: BMC Complementary and Alternative Medicine 2017 17:398
    Content type: Research article Published on:

  22. Chronic stress contributes to the development of brain disorders, such as neurodegenerative and psychiatric diseases. Oxidative damage is well known as a causative factor for pathogenic process in brain tissue...

    Authors: Hyun-Yong Lee, Jin-Seok Lee, Hyeong-Geug Kim, Won-Yong Kim, Seung-Bae Lee, Yung-Hyun Choi and Chang-Gue Son
    Citation: BMC Complementary and Alternative Medicine 2017 17:397
    Content type: Research article Published on:

  23. Arachidonic acid metabolism by cyclooxygenase (COX) is a major pathway for blood platelets’ activation, which is associated with pro-thrombotic platelet activity and the production of pro-inflammatory mediator...

    Authors: Michal Bijak and Joanna Saluk-Bijak
    Citation: BMC Complementary and Alternative Medicine 2017 17:396
    Content type: Research article Published on:

  24. [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is involved in insulin secretion and is perturbed in db/db ...

    Authors: Mehdi Bin Samad, Md. Nurul Absar Bin Mohsin, Bodiul Alam Razu, Mohammad Tashnim Hossain, Sinayat Mahzabeen, Naziat Unnoor, Ishrat Aklima Muna, Farjana Akhter, Ashraf Ul Kabir and J. M. A. Hannan
    Citation: BMC Complementary and Alternative Medicine 2017 17:395
    Content type: Research article Published on:

  25. Although pharmacists are entrusted to play a role in ensuring the safe and appropriate use of all medicines, in general, the inclusion of complementary medicines (CMs) into their professional practice has not ...

    Authors: Carolina Oi Lam Ung, Joanna Harnett and Hao Hu
    Citation: BMC Complementary and Alternative Medicine 2017 17:394
    Content type: Research article Published on:

  26. A variety of anticancer chemotherapeutics induce adverse side effects including myelotoxicity. Dried roots of Phragmites communis Trinius, Phragmitis rhizoma, have been clinically used in traditional folk medicin...

    Authors: Jinhee Kim, You Jin Lee, Young Ah Kim, Eun-Sang Cho, Eunna Huh, Ok-Sun Bang and No Soo Kim
    Citation: BMC Complementary and Alternative Medicine 2017 17:393
    Content type: Research article Published on:

  27. It has been reported that royal jelly would reduce melanin synthesis and inhibit the expression of melanogensis related proteins and genes. In this study, we evaluate the anti-melanogenic and depigmenting acti...

    Authors: Chi-Chung Peng, Hui-Tzu Sun, I-Ping Lin, Ping-Chung Kuo and Jen-Chieh Li
    Citation: BMC Complementary and Alternative Medicine 2017 17:392
    Content type: Research article Published on:

  28. Bruxism is a repetitive activity that causes tooth wear, audible sounds, and discomfort. Preventive measures have been studied for conditions that can exert a negative influence on physiological development in...

    Authors: Mônica da Consolação Canuto Salgueiro, Carolina Carvalho Bortoletto, Anna Carolina RattoTempestini Horliana, Ana Carolina Costa Mota, Lara Jansiski Motta, Pamella de Barros Motta, Raquel Agnelli MesquitaFerrari, Kristianne Porta Santos Fernandes and Sandra Kalil Bussadori
    Citation: BMC Complementary and Alternative Medicine 2017 17:391
    Content type: Study protocol Published on:

  29. Colorectal cancer imposes threats to patients’ well-being. Although most physical symptoms can be managed by medication, psychosocial stressors may complicate survival and hamper quality of life. Mindfulness a...

    Authors: Rainbow T. H. Ho, Adrian H. Y. Wan, Jessie S. M. Chan, S. M. Ng, K. F. Chung and Cecilia L. W. Chan
    Citation: BMC Complementary and Alternative Medicine 2017 17:390
    Content type: Study protocol Published on:

  30. The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereot...

    Authors: Patrick Amoateng, Samuel Adjei, Dorcas Osei-safo, Kennedy K. E. Kukuia, Emelia Oppong Bekoe, Thomas K. Karikari and Samuel B. Kombian
    Citation: BMC Complementary and Alternative Medicine 2017 17:389
    Content type: Research article Published on:

  31. Plants are an efficient source of natural antioxidant against free radicals causing kidney damages. Sida cordata ethyl acetate fraction has been reported for strong in vitro antioxidant potency, previously. In th...

    Authors: Naseer Ali Shah, Muhammad Rashid Khan and Dereje Nigussie
    Citation: BMC Complementary and Alternative Medicine 2017 17:388
    Content type: Research article Published on:

  32. Herbology is the prevailing system among the nationally-accepted alternative or complementary systems of medicine. The system is due to its general and patient-oriented methodology, is widely used in the gener...

    Authors: Saiqa Ishtiaq, Maida Akram, Sairah Hafeez Kamran, Uzma Hanif, Muhammad Shaharyar Khan Afridi, Sajid-ur-Rehman, Atika Afzal, Ayesha Asif, Muhammad Younus and Shehla Akbar
    Citation: BMC Complementary and Alternative Medicine 2017 17:387
    Content type: Research article Published on:

  33. Plants have served either as a natural templates for the development of new chemicals or a phytomedicine since antiquity. Therefore, the present study was aimed to appraise the polarity directed antioxidant, c...

    Authors: Madiha Ahmed, Humaira Fatima, Muhammad Qasim, Bilquees Gul and Ihsan-ul-Haq
    Citation: BMC Complementary and Alternative Medicine 2017 17:386
    Content type: Research article Published on:

  34. As per the recent statistical reports of World Health Organisation (WHO), 13% of total global population is obese. Orlistat remains to be the only drug approved for the long term treatment of obesity. Recent f...

    Authors: M. Katoch, A. Paul, G. Singh and S. N. C. Sridhar
    Citation: BMC Complementary and Alternative Medicine 2017 17:385
    Content type: Research article Published on:

  35. Benign prostatic hyperplasia (BPH) is non-cancerous condition of enlargement of the prostate, a common occurrence in older men. The immature fruits of Poncirus trifoliata (L.) Rafinesque (Rutaceae), Ponciri Fruct...

    Authors: Woo-Young Jeon, Ohn Soon Kim, Chang-Seob Seo, Seong Eun Jin, Jung-Ae Kim, Hyeun-Kyoo Shin, Yong-ung Kim and Mee-Young Lee
    Citation: BMC Complementary and Alternative Medicine 2017 17:384
    Content type: Research article Published on:

  36. Ficus umbellata is a medicinal plant previously shown to endow estrogenic properties. Its major component was isolated and characterized as 7-methoxycoumarin (MC). Noteworthy, coumarin...

    Authors: Stéphane Zingue, Thomas Michel, Chantal Beatrice Magne Nde, Amstrong Nang Njuh, Julia Cisilotto, Derek Tantoh Ndinteh, Colin Clyne, Xavier Fernandez, Tânia Beatriz Creczynski-Pasa and Dieudonné Njamen
    Citation: BMC Complementary and Alternative Medicine 2017 17:383
    Content type: Research article Published on:

  37. There is a paucity of literature describing traditional health practices and beliefs of African women. The purpose of this study was to undertake a systematic review of the use of traditional medicine (TM) to ...

    Authors: Zewdneh Shewamene, Tinashe Dune and Caroline A. Smith
    Citation: BMC Complementary and Alternative Medicine 2017 17:382
    Content type: Research article Published on:

  38. Epidemiological and experimental evidences have shown cancer as a leading cause of death worldwide. Although the folklore use of plants as a reliable source of health-restoring principles is well-documented, t...

    Authors: Jeremiah Olorunjuwon Olugbami, Robert Damoiseaux, Bryan France, Esther Modupe Onibiyo, Michael Adedapo Gbadegesin, Shivani Sharma, James Kazimierz Gimzewski and Oyeronke Adunni Odunola
    Citation: BMC Complementary and Alternative Medicine 2017 17:381
    Content type: Research article Published on:

  39. Asthma is characterized by chronic airway inflammation, leading to structura1 changes in the airway, collectively termed airway remodeling. Airway remodeling is thought to contribute to airway hyper responsive...

    Authors: Xiufeng Tang, Honglei Nian, Xiaoxi Li, Yan Yang, Xiujuan Wang, Liping Xu, Haotian Shi, Xinwei Yang and Renhui Liu
    Citation: BMC Complementary and Alternative Medicine 2017 17:380
    Content type: Research article Published on:

  40. The ethnic population of Arunachal Pradesh uses a number of orchids as such, or in decoction for various ailments. Three untapped orchids namely, Rhynchostylis retusa, Tropidia curculioides and Satyrium nepalense...

    Authors: Manisha Bhatnagar, Nandan Sarkar, Nigam Gandharv, Ona Apang, Sarman Singh and Sabari Ghosal
    Citation: BMC Complementary and Alternative Medicine 2017 17:379
    Content type: Research article Published on:

  41. Prostate cancer is the most common cancer in men in the United States. Fucoidan is a bioactive polysaccharide extracted mainly from algae. The aim of this study was to investigate anti-tumor and anti-angiogeni...

    Authors: Xin Rui, Hua-Feng Pan, Si-Liang Shao and Xiao-Ming Xu
    Citation: BMC Complementary and Alternative Medicine 2017 17:378
    Content type: Research article Published on:

  42. Cancer cachexia is associated with increased pro-inflammatory cytokine levels. Centella asiatica (C. asiatica) possesses antioxidant, anti-inflammatory and anti-tumour potential. We investigated the modulation of...

    Authors: Dhaneshree Bestinee Naidoo, Anil Amichund Chuturgoon, Alisa Phulukdaree, Kanive Parashiva Guruprasad, Kapaettu Satyamoorthy and Vikash Sewram
    Citation: BMC Complementary and Alternative Medicine 2017 17:377
    Content type: Research article Published on:

  43. In northeastern Brazil, grape pomace has become a potential alternative byproduct because of the recover phenolic compounds from the vinification process. Comparative analyses were performed between lyophilize...

    Authors: José George F. Albuquerque, Valéria L. Assis, Arthur J. P. O. Almeida, Ionaldo J. L. D. Basílio, Melissa N. Luciano, Bruno R. L. A. Meireles, Ângela M. T. M. Cordeiro, Islânia G. A. Araújo, Robson C. Veras, Thaís P. Ribeiro and Isac A. Medeiros
    Citation: BMC Complementary and Alternative Medicine 2017 17:376
    Content type: Research article Published on:

  44. YY-312 is a herbal extract powder from Imperata cylindrica Beauvois, Citrus unshiu Markovich, and Evodia officinalis Dode, which have health promoting effects, including body fat reduction. We aimed to evaluate t...

    Authors: Young-Gyu Cho, Ji-Hye Jung, Jae-Heon Kang, Jin Soo Kwon, Seung Pil Yu and Tae Gon Baik
    Citation: BMC Complementary and Alternative Medicine 2017 17:375
    Content type: Research article Published on:

  45. SC-E1 is a novel herbal formula consisting of five oriental medicinal herbs used frequently in traditional herbal medicine for the treatment of inflammatory diseases in Korea. This study examined the effects o...

    Authors: Ju-Yeon Park, Young-Won Kwon, Soo Chil Lee, Sun-Dong Park and Ju-Hee Lee
    Citation: BMC Complementary and Alternative Medicine 2017 17:374
    Content type: Research article Published on:

  46. Chebulic acid (CA) isolated from T. chebula, which has been reported for treating asthma, as a potent anti-oxidant resources. Exposure to ambient urban particulate matter (UPM) considered as a risk for cardiopulm...

    Authors: Kyung-Won Lee, Mi-Hyun Nam, Hee-Ra Lee, Chung-Oui Hong and Kwang-Won Lee
    Citation: BMC Complementary and Alternative Medicine 2017 17:373
    Content type: Research article Published on:

  47. The emergence of drug resistant malaria is threatening our ability to treat and control malaria in the Southeast Asian region. There is an urgent need to develop novel and chemically diverse antimalarial drugs...

    Authors: Muhammad Bilal Sadiq, Pattamon Tharaphan, Kesinee Chotivanich, Joel Tarning and Anil Kumar Anal
    Citation: BMC Complementary and Alternative Medicine 2017 17:372
    Content type: Research article Published on:

  48. The roots and stem bark of Berberis orthobotrys (Berberidaceae) have long been used traditionally to treat joint pain. Though, it has not been pharmacologically assessed for rheumatoid arthritis. The current stud...

    Authors: Alamgeer, Ambreen Malik Uttra and Umme Habiba Hasan
    Citation: BMC Complementary and Alternative Medicine 2017 17:371
    Content type: Research article Published on:

  49. Solanum nigrum, herbal plant that commonly grows in temperate climate zone, has been used as a traditional folk medicine whose ripen fruits were proven to exhibit anti-tumor properties...

    Authors: Sankar Jagadeeshan, Diana David, S. Jisha, S. Manjula and S. Asha Nair
    Citation: BMC Complementary and Alternative Medicine 2017 17:370
    Content type: Research article Published on:

  50. Zanthoxylum armatum DC has been an important traditional plant known for its medicinal properties. It is well known for its antimicrobial, larvicidal and cytotoxic activities.

    Authors: Fiaz Alam, Qazi Najum us Saqib and Abdul Waheed
    Citation: BMC Complementary and Alternative Medicine 2017 17:368
    Content type: Research article Published on:
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