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  1. Propolis is a natural bee product with a wide range of biological activities that are related to its chemical composition. The present study investigated the quantification of quercetin (Q) in Ardabil ethanol ...

    Authors: Fariba Asgharpour, Ali Akbar Moghadamnia, Ebrahim Zabihi, Sohrab Kazemi, Amirmorteza Ebrahimzadeh Namvar, Hemmat Gholinia, Mina Motallebnejad and Hamid Reza Nouri
    Citation: BMC Complementary and Alternative Medicine 2019 19:266
  2. Carica papaya (CP) extract is becoming popular as an unlicensed herbal remedy purported to hasten recovery in dengue infection, mostly based on observations that it may increase platelet counts. This systematic r...

    Authors: Senaka Rajapakse, Nipun Lakshitha de Silva, Praveen Weeratunga, Chaturaka Rodrigo, Chathurani Sigera and Sumadhya Deepika Fernando
    Citation: BMC Complementary and Alternative Medicine 2019 19:265
  3. Osteoarthritis (OA) is a common degenerative disease of synovial joints caused by inflammation. Acteoside (ACT), a major component and lipase inhibitor from the Chinese tea Ligustrum purpurascens kudingcha, has b...

    Authors: Zhiguang Qiao, Jiaxin Tang, Wen Wu, Jian Tang and Ming Liu
    Citation: BMC Complementary and Alternative Medicine 2019 19:264
  4. Inflammation is a symptom associated with many diseases. This symptom is treated with steroidal and non-steroidal anti-inflammatory drugs, which can cause severe side effects when used as long-term treatments....

    Authors: Axel Villagómez-Rodríguez, Julia Pérez-Ramos, Ana Laura Esquivel-Campos, Cuauhtémoc Pérez-González, Claudia Angélica Soto-Peredo and Salud Pérez-Gutiérrez
    Citation: BMC Complementary and Alternative Medicine 2019 19:263
  5. Natural products play a significant role in human health in relation to the prevention and treatment of inflammatory conditions. One of the plants with great medicinal potentials is Diospyros kaki which is mainly...

    Authors: Jieun Choi, Mi Jeong Kim, Richard Komakech, Haiyoung Jung and Youngmin Kang
    Citation: BMC Complementary and Alternative Medicine 2019 19:262
  6. Our previous study exhibited free radicals scavenging and antioxidant activities of ethanolic and aqueous extracts of Tamarindus indica L. leaves in chronic sodium fluoride poisoning in rats. Tamarindus indica L....

    Authors: Bishnu Prasad Sinha, Souvick Chatterjee, Rinku Buragohain, Indranil Samanta, Siddhartha Narayan Joardar, Prasenjit Mukherjee, Asit Kumar Maji, Partha Das, Tapan Kumar Mandal and Tapas Kumar Sar
    Citation: BMC Complementary and Alternative Medicine 2019 19:261
  7. Dengue is a mosquito-borne viral infection that has become a major public health concern worldwide. Presently, there is no specific vaccine or treatment available for dengue viral infection.

    Authors: Kavithambigai Ellan, Ravindran Thayan, Jegadeesh Raman, Kazuya I. P. J. Hidari, Norizah Ismail and Vikineswary Sabaratnam
    Citation: BMC Complementary and Alternative Medicine 2019 19:260

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2023 23:86

  8. Traditional and complementary medicines (T&CM) are any form of medicine, practice, treatment, product, technology, knowledge system or ceremony outside of conventional medical practice that aims to prevent and...

    Authors: A. Gall, K. Anderson, J. Adams, V. Matthews and G. Garvey
    Citation: BMC Complementary and Alternative Medicine 2019 19:259
  9. Herbal and traditional medicines (HTM) are widely used in Asian countries. Specific data on prevalent of HTM usage and association with chronic diseases in the Thai population is currently lacking. We examined...

    Authors: Napatt Kanjanahattakij, Pakakrong Kwankhao, Prin Vathesatogkit, Nisakron Thongmung, Yingampa Gleebbua, Piyamitr Sritara and Chagriya Kitiyakara
    Citation: BMC Complementary and Alternative Medicine 2019 19:258
  10. Clinacanthus nutans extracts have been consumed by the cancer patients with the hope that the extracts can kill cancers more effectively than conventional chemotherapies. Our previous study reported its anti-infl...

    Authors: Ling-Wei Hii, Swee-Hua Erin Lim, Chee-Onn Leong, Swee-Yee Chin, Ngai-Paing Tan, Kok-Song Lai and Chun-Wai Mai
    Citation: BMC Complementary and Alternative Medicine 2019 19:257
  11. Arisaema jacquemontii is traditionally used in treatment of different diseases. In this study, phytochemical, in vitro biological and chemo-preventive screening of A. jacquemontii was carried out to explore its p...

    Authors: Saira Tabassum, Muhammad Zia, Esperanza J. Carcahe de Blanco, Riffat Batool, Roohi Aslam, Sajid Hussain, Qamar Wali and Muhammad Mudassar Gulzar
    Citation: BMC Complementary and Alternative Medicine 2019 19:256
  12. Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initi...

    Authors: Ke Fang, Fan Wu, Guang Chen, Hui Dong, Jingbin Li, Yan Zhao, Lijun Xu, Xin Zou and Fuer Lu
    Citation: BMC Complementary and Alternative Medicine 2019 19:255
  13. Fumaria species (Fumariacea) has traditionally been used in wound healing in Iranian folk medicine. However, with the discovery of newer agents, its use has faded off into total obscurity. This study explored the...

    Authors: Fatemeh Davoodi-Roodbordeii, Minoo Afshar, Fatemeh Haji Abas Tabrizi, Samira Choopani, Giti Torkaman, Fariborz Moayer and Mona Salimi
    Citation: BMC Complementary and Alternative Medicine 2019 19:254
  14. General antiviral agents such as oseltamivir are associated with certain adverse effects and the emergence of resistance. This study investigated the phytochemical properties, antiviral activities, and safety ...

    Authors: Won-Young Bae, Hyeong-Yeop Kim, Kyoung-Sook Choi, Kyung Hoon Chang, Young-Ho Hong, Jongsu Eun, Na-Kyoung Lee and Hyun-Dong Paik
    Citation: BMC Complementary and Alternative Medicine 2019 19:253
  15. Turmeric is commonly used as a dietary treatment for inflammation, but few studies have evaluated the direct effect of turmeric on cartilage. The purpose of this study was to characterize cartilage explants’ i...

    Authors: Wendy Pearson and Laima S. Kott
    Citation: BMC Complementary and Alternative Medicine 2019 19:252
  16. While traditional, complementary and alternative medicine (TCAM) is gaining increased interest worldwide, the structural factors associated with the usage of TCAM at the social level have not been sufficiently...

    Authors: Jimpei Misawa, Rie Ichikawa, Akiko Shibuya, Yukihiro Maeda, Ichiro Arai, Teruyoshi Hishiki and Yoshiaki Kondo
    Citation: BMC Complementary and Alternative Medicine 2019 19:251
  17. Parents’ use of complementary health approaches (CHA) for children with autism spectrum disorder (ASD) are common despite the uncertain evidence of its benefit. Parents often adopt CHA due to dissatisfaction w...

    Authors: Jun Jean Ong
    Citation: BMC Complementary and Alternative Medicine 2019 19:250
  18. Bacteria have developed resistance to most of the current antibiotics. There is evidence suggesting that plant-derived compounds have a potential for interacting with biological processes. One of the plants co...

    Authors: Winnie Mozirandi, Dexter Tagwireyi and Stanley Mukanganyama
    Citation: BMC Complementary and Alternative Medicine 2019 19:249
  19. With the current concern caused by drug resistant microorganisms, alternatives to traditional antimicrobials are increasingly necessary. Historical holistic treatments involving natural approaches are now of i...

    Authors: Rhegan C. McGregor, Kory A. Parker, Jacob M. Hornby and Leigh C. Latta IV
    Citation: BMC Complementary and Alternative Medicine 2019 19:247
  20. Cosmos caudatus is an annual plant known for its medicinal value in treating several health conditions, such as high blood pressure, arthritis, and diabetes mellitus. The α-glucosidase inhibitory activity and tot...

    Authors: Wan Ahmad Wan-Nadilah, Muhammad Tayyab Akhtar, Khozirah Shaari, Alfi Khatib, Azizah Abdul Hamid and Muhajir Hamid
    Citation: BMC Complementary and Alternative Medicine 2019 19:245
  21. Catalpol, a natural iridoid glycoside in Rehmannia glutinosa, can alleviate proteinuria associated with diabetic nephropathy (DN), however, whether catalpol has a protective effect against podocyte injury in DN r...

    Authors: Yan Chen, Qingpu Liu, Zengfu Shan, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng and Weisheng Feng
    Citation: BMC Complementary and Alternative Medicine 2019 19:244
  22. Brown adipocytes are known to promote energy expenditure and limit weight gain to combat obesity. Averrhoa bilimbi, locally called belimbing buluh (DBB), is mainly used as an ethnomedicine in the treatment of met...

    Authors: Wai Kwan Lau, Nur Adelina Ahmad Noruddin, Abdul Hadi Ariffin, Muhd Zulkarnain Mahmud, Mohd Hasnan Mohd Noor, Azimah Amanah, Mohamad Faiz Hamzah and Zainuddin Zafarina
    Citation: BMC Complementary and Alternative Medicine 2019 19:243
  23. Cyanidin-3-rutinoside (C3R), a naturally occurring anthocyanin, possesses anti-oxidant, anti-hyperglycemic, anti-glycation and cardioprotective properties. However, its mechanisms responsible for anti-hyperlip...

    Authors: Thavaree Thilavech and Sirichai Adisakwattana
    Citation: BMC Complementary and Alternative Medicine 2019 19:242
  24. Mulberry silkworm larvae (Bombyx mori) are known as the oldest resource of food and traditional medicine. Although silkworm larvae have been reported to treat various chronic diseases, the effect of fermentation ...

    Authors: Hyun-Dong Cho, Hye-Ji Min, Yeong-Seon Won, Hee-Young Ahn, Young-Su Cho and Kwon-Il Seo
    Citation: BMC Complementary and Alternative Medicine 2019 19:241
  25. Major depression is an important complication in patients with breast cancer, but is an underrecognized and undertreated condition in this population. The Baihe Zhimu Tang (BZ formula) is a traditional Chinese...

    Authors: Hailong Li, Chunyu Wu, Yu Liu, Shuo Zhang and Xiufei Gao
    Citation: BMC Complementary and Alternative Medicine 2019 19:240
  26. Chronic obstructive pulmonary disease (COPD) is one global disease. Lung function gradually declines. Medication does not fully reverse the airflow limitation. Qigong’s role in COPD rehabilitation has been ass...

    Authors: Hongxuan Tong, Yihua Liu, Yutian Zhu, Boli Zhang and Jingqing Hu
    Citation: BMC Complementary and Alternative Medicine 2019 19:239
  27. Annonacin, an annonaceous acetogenin isolated from Annona muricata has been reported to be strongly cytotoxic against various cell lines, in vitro. Nevertheless, its effect against in vivo tumor promoting activit...

    Authors: Mohd Rohaizad Md Roduan, Roslida Abd Hamid and Norhafizah Mohtarrudin
    Citation: BMC Complementary and Alternative Medicine 2019 19:238
  28. Rice husk, a waste material produced during milling, contains numerous phytochemicals that may be sources of cancer chemopreventive agents. Various biological activities of white and colored rice husk have bee...

    Authors: Arpamas Chariyakornkul, Charatda Punvittayagul, Sirinya Taya and Rawiwan Wongpoomchai
    Citation: BMC Complementary and Alternative Medicine 2019 19:237
  29. Syzygium cumini (L.) Skeels. is one of the very popular traditionally used medicinal plants with numerous pharmacological activities including antioxidant, hypoglycemic and anti-inflammatory. However, actions of

    Authors: Ahad Abdul Rehman, Azra Riaz, Muhammad Arif Asghar, Muhammad Liaquat Raza, Shadab Ahmed and Kamran Khan
    Citation: BMC Complementary and Alternative Medicine 2019 19:236
  30. Oxyresveratrol is a major bioactive component derived from the heartwood of Artocarpus lacucha. This compound exerts several biological activities, including neuroprotective effects in vitro and in vivo. However,...

    Authors: Dhirarin Junsaeng, Tosapol Anukunwithaya, Phanit Songvut, Boonchoo Sritularak, Kittisak Likhitwitayawuid and Phisit Khemawoot
    Citation: BMC Complementary and Alternative Medicine 2019 19:235
  31. The neurobiology of persistent pain shares common underlying psychobiology with that of traumatic stress. Modern treatments for traumatic stress often involve bottom-up sensorimotor retraining/exposure therapi...

    Authors: Alison Flehr, Christopher Barton, Jan Coles, Stephen J. Gibson, Gavin W. Lambert, Elisabeth A. Lambert, Arup K. Dhar and John B. Dixon
    Citation: BMC Complementary and Alternative Medicine 2019 19:234
  32. Resveratrol is reported to inhibit the growth of prostate, which is characteristic of benign prostatic hyperplasia (BPH) condition. However, the mechanism remains unclear. This study aimed to identify the effe...

    Authors: Chao Li, Wan-Li Hu, Meng-Xin Lu and Guan-Fa Xiao
    Citation: BMC Complementary and Alternative Medicine 2019 19:233
  33. Metabolic syndrome is a non-communicable disease inclusive of risk factors such as central obesity, hypertension, hyperglycaemia and dyslipidaemia. In this present study, we investigated the ability of Pandanus a...

    Authors: Nur Hidayah Reshidan, Suhaila Abd Muid and Norshalizah Mamikutty
    Citation: BMC Complementary and Alternative Medicine 2019 19:232
  34. In Korea and China, asiasari radix (AR) is widely used as a traditional anti-inflammatory and analgesic agent. After its skin-regenerating and hair loss-preventing activities were identified, several types of ...

    Authors: Kwang-Ha Park, Jeong-Hae Choi, Yeon-Suk Song, Gyoo-Cheon Kim and Jin-Woo Hong
    Citation: BMC Complementary and Alternative Medicine 2019 19:231
  35. Hyperglycemia and dyslipidemia are classic features of patients with diabetes mellitus (DM). Cordyceps taii, a folk medicinal fungus native to southern China, possesses various pharmacological activities. This st...

    Authors: Ru-Ming Liu, Rong Dai, Yi Luo and Jian-Hui Xiao
    Citation: BMC Complementary and Alternative Medicine 2019 19:230
  36. Use of complementary and alternative medicine (CAM), including vitamins, minerals, herbals, and other dietary supplements, is widespread in the United States (ranging from 24% in Hispanics to 50% in American I...

    Authors: Srujitha Marupuru, David Rhys Axon and Marion K. Slack
    Citation: BMC Complementary and Alternative Medicine 2019 19:229
  37. Non-alcoholic fatty liver disease (NAFLD) may increase the sensitivity to liver injury caused by stimulants such as drugs and poisons. The traditional Chinese medicine (TCM) Jiang-Zhi Granule (JZG) has been prove...

    Authors: Lili Yang, Yan Zhou, Haiyan Song and Peiyong Zheng
    Citation: BMC Complementary and Alternative Medicine 2019 19:228
  38. Oxidative stress is an imbalance between the levels of reactive oxygen species (ROS), reactive nitrogen species (RNS) and endogenous antioxidants. The aetiology and pathogenesis of several oral diseases are at...

    Authors: Ignacio Peralta, Carla Marrassini, María Laura Barreiro Arcos, Graciela Cremaschi, María Rosario Alonso and Claudia Anesini
    Citation: BMC Complementary and Alternative Medicine 2019 19:227
  39. Six Chinese herb formulas, namely, the Weijing decoction (WJ), the Maxingshigan decoction (MXSG), the Yuebijiabanxia decoction (YBBX), the Qingqihuatan decoction (QQHT), the Dingchuan decoction (DC) and the Sa...

    Authors: Shaonan Liu, Jing Chen, Jinhong Zuo, Jiaqi Lai, Lei Wu and Xinfeng Guo
    Citation: BMC Complementary and Alternative Medicine 2019 19:226
  40. We aimed to evaluate the global scientific output of research of acupuncture on insomnia and explore the hotspots and frontiers from 1999 to 2018, by using bibliometric methods.

    Authors: Wenya Pei, Rui Peng, Yuan Gu, Xiaohong Zhou and Jingwen Ruan
    Citation: BMC Complementary and Alternative Medicine 2019 19:225
  41. Commercial herbal medicines (CHMs) marketed as immune boosters are gaining wide popularity in South Africa, in the absence of control and regulatory guidelines. These commercially packaged and labelled herbal ...

    Authors: Mmamosheledi E. Mothibe, Christina P. Kahler-Venter and Elzbieta Osuch
    Citation: BMC Complementary and Alternative Medicine 2019 19:224
  42. We aimed to compare patients’ and physicians’ safety reporting using data from large acupuncture trials (44,818 patients) and to determine associations between patient characteristics and reporting of adverse ...

    Authors: Thea Schwaneberg, Claudia M. Witt, Stephanie Roll and Daniel Pach
    Citation: BMC Complementary and Alternative Medicine 2019 19:223
  43. Chronic hepatic diseases are serious problems worldwide, which may lead to the development of fibrosis and eventually cirrhosis. Despite the significant number of people affected by hepatic fibrosis, no effect...

    Authors: Caio Mateus da Silva, Flávio Henrique Caetano, Franco Dani Campos Pereira, Maria Aparecida Marin Morales, Kumiko Koibuchi Sakane and Karen C. M. Moraes
    Citation: BMC Complementary and Alternative Medicine 2019 19:222
  44. Lichens produce a huge diversity of bioactive compounds with several biological effects. Gyrophoric acid (GA) is found in high concentrations in the common lichen Umbilicaria hirsuta, however evidence for biologi...

    Authors: Michal Goga, Martin Kello, Maria Vilkova, Klaudia Petrova, Martin Backor, Wolfram Adlassnig and Ingeborg Lang
    Citation: BMC Complementary and Alternative Medicine 2019 19:221
  45. Baeckea frutescens (B. frutescens) of the family Myrtaceae is a plant that has been used in traditional medicine. It is known to have antibacterial, antipyretic and cytoprotective properties. The objective of thi...

    Authors: S. H. Shahruzaman, M. F. Mustafa, S. Ramli, S. Maniam, S. Fakurazi and S. Maniam
    Citation: BMC Complementary and Alternative Medicine 2019 19:220
  46. Methicillin-resistant Staphylococcus aureus (MRSA) causes serious infections in hospitals. Penthorum chinense Pursh (PCP), employed by the Miao ethnic minority in China, presents antibacterial activities. In this...

    Authors: Bin Ding, Qinchao Ding, Shun Zhang, Zhuo Jin, Zhaolei Wang, Songtao Li and Xiaobing Dou
    Citation: BMC Complementary and Alternative Medicine 2019 19:219
  47. Staphylococcal aureus (S. aureus) has become the leading causative pathogen of Prosthetic Joint Infection (PJI), which is the most devastating complication after arthroplasty surgeries. Due to the biofilm formati...

    Authors: Jiaqi Tan, Jin Wang, Chuang Yang, Chongzun Zhu, Geyong Guo, Jin Tang and Hao Shen
    Citation: BMC Complementary and Alternative Medicine 2019 19:218
  48. Systemic inflammation driven neuroinflammation is an event which correlates with pathogenesis of several neurodegenerative diseases. Therefore, targeting peripheral and central inflammation simultaneously coul...

    Authors: Muskan Gupta and Gurcharan Kaur
    Citation: BMC Complementary and Alternative Medicine 2019 19:217