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  1. About 70% of Ghanaians depend on traditional, complementary and integrative medicine (TCIM) practices for primary healthcare needs. It was therefore integrated into mainstream healthcare delivery system by the...

    Authors: Angela Kenu, Ernest Kenu, Delia Akosua Bandoh and Moses Aikins
    Citation: BMC Complementary Medicine and Therapies 2021 21:14
    Content type: Research article Published on:

  2. Activation of renal fibroblasts is a critical mechanism in the process of renal fibrosis. As a commonly used herbal formula, Shenkang (SK) has been found to attenuate renal fibrosis and renal parenchyma destru...

    Authors: Tianyu Qin, You Wu, Tonghua Liu and Lili Wu
    Citation: BMC Complementary Medicine and Therapies 2021 21:12
    Content type: Research article Published on:

  3. Stroke causes lasting brain damage that has numerous impacts on the survivor’s physical, psychosocial, and spiritual well-being. Young survivors (< 65 years old) tend to suffer more because of their longer ove...

    Authors: Caitlin Kar Pui Chan, Temmy Lee Ting Lo, Adrian Ho Yin Wan, Pamela Pui Yu Leung, Marco Yiu Chung Pang and Rainbow Tin Hung Ho
    Citation: BMC Complementary Medicine and Therapies 2021 21:7
    Content type: Study protocol Published on:

  4. Germacrone (GM) is a terpenoid compound which is reported to have anti-inflammatory and anti-oxidative effects. However, its role in treating traumatic brain injury (TBI) remains largely unknown.

    Authors: Sujing Zhuang, Baogui Liu, Shifeng Guo, Yanzhong Xue, Lin Wu, Shiqi Liu, Chunling Zhang and Xiuyan Ni
    Citation: BMC Complementary Medicine and Therapies 2021 21:6
    Content type: Research article Published on:

  5. Correspondence from Yu et al. identify methodological issues with the systematic review of manual therapy for pediatric manuscript. Like any research study, limitations are important for readers to keep in con...

    Authors: Katherine A. Pohlman, Kristian Anderson, Beth Carleo and Brian Gleberzon
    Citation: BMC Complementary Medicine and Therapies 2021 21:5
    Content type: Correspondence Published on:

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:4

  6. Prevost et al. published a systematic review evaluating the use of manual therapy for clinical conditions in the pediatric population in 2019. However, several methodological flaws in the conduct of the review...

    Authors: Hainan Yu, Heather Shearer, Anne Taylor-Vaisey, Silvano Mior, Leslie Verville, Gaelan Connell and Pierre Côté
    Citation: BMC Complementary Medicine and Therapies 2021 21:4
    Content type: Correspondence Published on:

    The Correspondence to this article has been published in BMC Complementary Medicine and Therapies 2021 21:5

  7. Generally, complementary and alternative therapies (CAT) are accepted methods of treatment by patients with various types of conditions. Their use is becoming especially prevalent among patients with eye probl...

    Authors: Dania Jaber, Rafat Abu Ghannam, Waleed Rashed, Mohammad Shehadeh and Sa’ed H. Zyoud
    Citation: BMC Complementary Medicine and Therapies 2021 21:3
    Content type: Research article Published on:

  8. Patients with lymphoedema are at high risk of getting bacterial and fungal wound infections leading to acute inflammatory episodes associated with cellulitis and erysipelas. In Ethiopia, wound infections are t...

    Authors: Dereje Nigussie, Gail Davey, Belete Adefris Legesse, Abebaw Fekadu and Eyasu Makonnen
    Citation: BMC Complementary Medicine and Therapies 2021 21:2
    Content type: Research article Published on:

  9. Hypercholesterolemia has posed a serious threat of heart diseases and stroke worldwide. Xanthine oxidase (XO), the rate-limiting enzyme in uric acid biosynthesis, is regarded as the root of reactive oxygen spe...

    Authors: Rishab Marahatha, Saroj Basnet, Bibek Raj Bhattarai, Prakriti Budhathoki, Babita Aryal, Bikash Adhikari, Ganesh Lamichhane, Darbin Kumar Poudel and Niranjan Parajuli
    Citation: BMC Complementary Medicine and Therapies 2021 21:1
    Content type: Research article Published on:

  10. Rhinoviruses and influenza viruses cause millions of acute respiratory infections annually. Symptoms of mild acute respiratory infections are commonly treated with over-the-counter products like ambroxol, brom...

    Authors: Christin Walther, Kristin Döring and Michaela Schmidtke
    Citation: BMC Complementary Medicine and Therapies 2020 20:380
    Content type: Research article Published on:

  11. Aloe’s reported bioactivities (anticancer, anti-inflammatory and wound healing) suggest they might inhibit a subgroup of matrix metalloproteinases (MMPs) called gelatinases (MMP-2 and MMP-9). The goal of the pres...

    Authors: Ana Lima, Paula Batista-Santos, Eduarda Veríssimo, Patrícia Rebelo and Ricardo Boavida Ferreira
    Citation: BMC Complementary Medicine and Therapies 2020 20:379
    Content type: Research article Published on:

  12. Diabetic cardiomyopathy is a main cause of the increased morbidity in diabetic patients, no effective treatment is available so far. Polydatin, a resveratrol glucoside isolated from the Polygonum cuspidatum, was ...

    Authors: Ying-Ying Tan, Lei-Xin Chen, Ling Fang and Qi Zhang
    Citation: BMC Complementary Medicine and Therapies 2020 20:378
    Content type: Research article Published on:

  13. Previous studies have found that Hugan Qingzhi tablet (HQT) has significant lipid-lowering and antioxidant effects on non-alcoholic fatty liver disease (NAFLD). Moreover, the results of proteomic analysis conf...

    Authors: Miaoting Yang, Zhijuan Chen, Shijian Xiang, Fan Xia, Waijiao Tang, Xiaorui Yao and Benjie Zhou
    Citation: BMC Complementary Medicine and Therapies 2020 20:377
    Content type: Research article Published on:

  14. Obesity and its associated diseases have become a major world-wide health problem. Purple-leaf Tea (Camellia sinensis L.) (PLT), that is rich of anthocyanins, has been shown to have preventive effects on obesity ...

    Authors: Yu-Chun Lin, Hsu-Feng Lu, Jui-Chieh Chen, Hsiu-Chen Huang, Yu-Hsin Chen, Yen-Shuo Su, Chien-Yi Tung and Cheng Huang
    Citation: BMC Complementary Medicine and Therapies 2020 20:376
    Content type: Research article Published on:

  15. Annona muricata L. was identified as a popular medicinal plant in treatment regimens among cancer patients in Jamaica by a previously conducted structured questionnaire. Ethnomedically used plant parts, were exam...

    Authors: Kimberley Foster, Omolola Oyenihi, Sunelle Rademan, Joseph Erhabor, Motlalepula Matsabisa, James Barker, Moses K. Langat, Amy Kendal-Smith, Helen Asemota and Rupika Delgoda
    Citation: BMC Complementary Medicine and Therapies 2020 20:375
    Content type: Research article Published on:

  16. This study aimed to evaluate the effects of the Acorus tatarinowii Schott [Shi Chang Pu (SCP)] extract administered at the start of 2 h of middle cerebral artery occlusion (MCAo), followed by 3 d of reperfusion, ...

    Authors: Yu-Chen Lee, Shung-Te Kao and Chin-Yi Cheng
    Citation: BMC Complementary Medicine and Therapies 2020 20:374
    Content type: Research article Published on:

  17. 4-Hydroxyisoleucine (4-HIL) is an active ingredient extracted from Trigonella foenum-graecum L., a Chinese traditional herbal medicine, which exerts the efficacy of anti-obesity and anti-diabetes. We previously r...

    Authors: Cong Zhou, Rui Chen, Feng Gao, Jiaoyue Zhang and Furong Lu
    Citation: BMC Complementary Medicine and Therapies 2020 20:373
    Content type: Research article Published on:

  18. The currently available treatments for colorectal cancer (CRC) are often associated with serious side-effects. Therefore, the development of a novel nutraceutical agent may provide an alternative complementary...

    Authors: Abilasha G. Jayathilake, Margaret F. Veale, Rodney Brain Luwor, Kulmira Nurgali and Xiao Q. Su
    Citation: BMC Complementary Medicine and Therapies 2020 20:372
    Content type: Research article Published on:

  19. The water extract of Quercuse infectoria galls (QIG) is the active ingredient of Uyghur medicine Xipayi Kui Jie’an (KJA) which has promising therapeutic effects on Ulcerative Colitis (UC) as an alternative med...

    Authors: Hui Zhang, Yongbing Wang, Jiayang Liu, Kudelaidi Kuerban, Jian Li, Mubarak Iminjan and Li Ye
    Citation: BMC Complementary Medicine and Therapies 2020 20:371
    Content type: Research article Published on:

  20. Insulin resistance could be associated with the development of Alzheimer disease (AD). The neuropathological hallmarks of AD are beta amyloid (Aβ) produced from sequential cleavage initiated by β-secretase and...

    Authors: Chien-Ning Huang, Chau-Jong Wang, Chih-Li Lin, Hsin-Hua Li, An-Ting Yen and Chiung-Huei Peng
    Citation: BMC Complementary Medicine and Therapies 2020 20:370
    Content type: Research article Published on:

  21. Liquidambaris Fructus is the infructescences of Liquidambar formosana Hance and it has been used to treat some breast disease in Traditional Chinese Medicine. In the previous study we found the anti-breast cancer...

    Authors: Ping Qian, Xiao-Ting Mu, Bing Su, Lu Gao and Dong-Fang Zhang
    Citation: BMC Complementary Medicine and Therapies 2020 20:369
    Content type: Research article Published on:

  22. Polyherbal formula (PHF) contains extract of Sauropus androgynous (L.) Merr., Trigonella foenum-graceum L., and Moringa oleifera Lam. considered to induce galactagogue activity. This research aimed to evaluate th...

    Authors: Mustofa, Fara Silvia Yuliani, Setyo Purwono, Ahmad Hamim Sadewa, Ema Damayanti and Didik Setyo Heriyanto
    Citation: BMC Complementary Medicine and Therapies 2020 20:368
    Content type: Research article Published on:

  23. This study aimed to investigate the mechanism of action of Panax notoginoside (PNS) against lung cancer and inhibition of lung cancer cell proliferation by the drug at different concentrations in a mouse model, c...

    Authors: Jizhou Zhang, Bin Zhou, Song Jin, Zhiyou Huang, Bidong Ma, Qiqi Shao and Wenzong Zhu
    Citation: BMC Complementary Medicine and Therapies 2020 20:367
    Content type: Research article Published on:

  24. The incidence and mortality of breast cancer in women is increasing worldwide. Breast cancer contains a subpopulation of cells known as cancer stem cells (CSCs). The CSCs are believed to be responsible for che...

    Authors: Nigatu Tuasha, Daniel Seifu, Endalamaw Gadisa, Beyene Petros and Stina Oredsson
    Citation: BMC Complementary Medicine and Therapies 2020 20:366
    Content type: Research article Published on:

  25. Momordica cochinchinensis (Cucurbitaceae) is a nutritionally and medicinally important fruit restricted to South East Asia with diverse morphological and genetic variations but there is limited information on its...

    Authors: Dilani Wimalasiri, Chaitali Dekiwadia, Siat Yee Fong, Terrence J. Piva and Tien Huynh
    Citation: BMC Complementary Medicine and Therapies 2020 20:365
    Content type: Research article Published on:

  26. Arctium lappa L. root (burdock root) has long been recommended for the treatment of different diseases in traditional Chinese medicine. Burdock root possesses anti-oxidative, anti-inflammatory, anti-cancer, and a...

    Authors: King-Chuen Wu, Hung-Kai Weng, Yun-Shang Hsu, Pin-Jia Huang and Yang-Kao Wang
    Citation: BMC Complementary Medicine and Therapies 2020 20:364
    Content type: Research article Published on:

  27. To determine similarities and differences in the reasons for using or not using complementary and alternative medicine (CAM) amongst general and condition-specific populations, and amongst populations in each ...

    Authors: Mayuree Tangkiatkumjai, Helen Boardman and Dawn-Marie Walker
    Citation: BMC Complementary Medicine and Therapies 2020 20:363
    Content type: Research article Published on:

  28. Gandi capsule is a traditional Chinese herbal formula used to promote blood circulation and removing blood stasis in clinical. Our previous study has shown that it reduces proteinuria with routine treatment in...

    Authors: Qiqiang Zhang, Qing Ye, Xiaohui Huang, Ajing Xu, Yan Liu, Jia Qi, Hai Zhang and Jian Zhang
    Citation: BMC Complementary Medicine and Therapies 2020 20:362
    Content type: Research article Published on:

  29. Identifying topics and assessing the reporting quality of Traditional Chinese Medicine (TCM) cohort studies.

    Authors: Yuting Duan, Zhirui Xu, Jingjing Deng, Yanjia Lin, Yan Zheng, Juexuan Chen, Xiaoyu Tang, Xuan Zhang, Chunzhi Tang, Jiangxia Miao and Zhaoxiang Bian
    Citation: BMC Complementary Medicine and Therapies 2020 20:361
    Content type: Research article Published on:

  30. Dental caries and periodontal disease are the most common chronic infectious oral diseases in the world. Acacia nilotica was commonly known in Sudan as Garad or Sunt has a wide range of medicinal uses. In the pre...

    Authors: Ali Mahmoud Muddathir, Ebtihal Abdalla M. Mohieldin and Tohru Mitsunaga
    Citation: BMC Complementary Medicine and Therapies 2020 20:360
    Content type: Research article Published on:

  31. Mangosteen, Garciniam angostana L., is a juicy fruit commonly found in Thailand. The rinds of Garciniam angostana L.have been used as a traditional medicine for the treatment of trauma, diarrhea and skin infec...

    Authors: P. Rukthong, N. Sereesongsang, T. Kulsirirat, N. Boonnak and K. Sathirakul
    Citation: BMC Complementary Medicine and Therapies 2020 20:359
    Content type: Research article Published on:

  32. Diarrhoea is a major health issue in both humans and animals and may be caused by bacterial, viral and fungal infections. Previous studies highlighted excellent activity of Newtonia buchananii and N. hildebrandti...

    Authors: Katlego E. Motlhatlego, Muna Ali Abdalla, Carmen M. Leonard, Jacobus N. Eloff and Lyndy J. McGaw
    Citation: BMC Complementary Medicine and Therapies 2020 20:358
    Content type: Research article Published on:

  33. Non-healing wounds have been a severe issue in the global healthcare system. Regrettably, royal jelly, a traditional remedy for various skin injuries, has not been widely applied in cutaneous wounds in clinica...

    Authors: Yan Lin, Meng Zhang, Luying Wang, Tianxing Lin, Guanggao Wang, Jianhua Peng and Songkun Su
    Citation: BMC Complementary Medicine and Therapies 2020 20:357
    Content type: Research article Published on:

  34. The present study establishes the cardioprotective role of Thraatchathi Chooranam (TC), a polyherbal traditional Siddha medicine, in terms of membrane stabilizing and antioxidant properties in isoproterenol (I...

    Authors: Ramakrishnan Ganapathy, Anita Ramachandran, Sushmitha Basavapattana Shivalingaiah, Muhammed Bishir, Saravanan Bhojaraj, Shivashree Sridhar, Surapaneni Krishna Mohan, Vishnu Priya Veeraraghavan, Saravana Babu Chidambaram, Musthafa Mohamed Essa and M. Walid Qoronfleh
    Citation: BMC Complementary Medicine and Therapies 2020 20:356
    Content type: Research article Published on:

  35. Colon cancer is the third most deadly and one of the most diagnosed diseases in the world. Although routine screening and early detection during last decades has improved the survival, colon cancer still claim...

    Authors: Vinod kumar Nelson, Nalini Kanta Sahoo, Madhusmita Sahu, Hari hara Sudhan, Chitikela P. Pullaiah and Kanuri Sai Muralikrishna
    Citation: BMC Complementary Medicine and Therapies 2020 20:355
    Content type: Research article Published on:

  36. An external herbal dispensary (EHD) is a type of pharmacy that provides various types of personalized herbal medicines (PHMs) to other traditional Korean medicine (TKM) institutions. Such dispensaries were leg...

    Authors: Soo-Hyun Sung, Ji-Eun Han, Ji-Yeon Ryu, Angela Dong-Min Sung, Jung-Youn Park, In-Hyuk Ha, Kyeong Han Kim, Jang-Kyung Park and Byung-Cheul Shin
    Citation: BMC Complementary Medicine and Therapies 2020 20:354
    Content type: Research article Published on:

  37. Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by severe acute respiratory syndrome coronavirus 2, and responsible for a global pandemic. Despite there being no known vaccines or medi...

    Authors: Jeremy Y. Ng
    Citation: BMC Complementary Medicine and Therapies 2020 20:353
    Content type: Research article Published on:

  38. Boswellia sacra resin has been commonly used as analgesic, antimicrobial, and anti-inflammatory properties, which reflect its immunomodulatory activity. Dendritic cells (DCs) are specialized antigen-presenting ce...

    Authors: Alia M. Aldahlawi, Amani T. Alzahrani and Mohamed F. Elshal
    Citation: BMC Complementary Medicine and Therapies 2020 20:352
    Content type: Research article Published on:

  39. This study aimed to identify the key genes and KEGG pathways in Carthamus tinctorius L. (Safflower) and Salvia miltiorrhiza Burge. (Salvia) for the treatment of cardio-cerebrovascular disease, and to explore thei...

    Authors: Yu Wang, Yajun Shi, Junbo Zou, Xiaofei Zhang, Yulin Liang, Jia Tai, Chunli Cui, Mei Wang and Dongyan Guo
    Citation: BMC Complementary Medicine and Therapies 2020 20:351
    Content type: Research article Published on:

  40. Tangzhiqing (TZQ), as a potential α-glycosidase inhibitor, possesses postprandial hypoglycaemic effects on maltose in humans. The aim of this study was to investigate the mechanisms by which TZQ attenuates pos...

    Authors: Yanfen Li, Xiaomao Zhang, Ruihua Wang, Lu Han, Wei Huang, Hong Shi, Baohe Wang, Ziqiang Li and Shaolan Zou
    Citation: BMC Complementary Medicine and Therapies 2020 20:350
    Content type: Research article Published on:

  41. Australians report consulting with a naturopaths or herbalists to improve their wellbeing, yet little is known about the associations between these consultations and the patients’ health behaviours. This cross...

    Authors: Amie Steel, Stefania Tiveron, Rebecca Reid, Jon Wardle, Holger Cramer, Jon Adams, David Sibbritt and Romy Lauche
    Citation: BMC Complementary Medicine and Therapies 2020 20:349
    Content type: Research article Published on:

  42. Integrating complementary medicine into medical care promotes patient-oriented care. A well-informed and collaborative professional healthcare team is essential for effective and patient-safe implementation of...

    Authors: Angelika Homberg, Nadja Klafke, Svetla Loukanova and Katharina Glassen
    Citation: BMC Complementary Medicine and Therapies 2020 20:348
    Content type: Research article Published on:

  43. The aerial parts of Salvia miltiorrhiza, which was considered to be the waste part and discarded during the root harvest, is rich in protocatechuic aldehyde (PAI). This study investigated the health-promoting eff...

    Authors: Shuang Wu, Qingyu Wang, Jinquan Wang, Baoyu Duan, Qihe Tang, Zhuojian Sun, Jinlong Han, Chenggang Shan, Zhifen Wang and Zhihui Hao
    Citation: BMC Complementary Medicine and Therapies 2020 20:347
    Content type: Research article Published on:

  44. To understand the characteristics of prescriptions and costs in pediatric patients with acute upper respiratory infections (AURI) is important for the regulation of outpatient care and reimbursement policy. Th...

    Authors: Shan Wang, Lihua Liu, Jianchao Liu, Likun Miao, Qian Zhuang, Ning Guo, Jing Zhao, Quanzheng Li and Guoquan Ren
    Citation: BMC Complementary Medicine and Therapies 2020 20:346
    Content type: Research article Published on:

  45. Guanxin V (GXV), a traditional Chinese medicine (TCM), has been widely used to treat coronary artery disease (CAD) in clinical practice in China. However, research on the active components and underlying mecha...

    Authors: Bo Liang, Xiao-Xiao Zhang and Ning Gu
    Citation: BMC Complementary Medicine and Therapies 2020 20:345
    Content type: Research article Published on:

  46. The aim of the trial was to investigate the effect of a hypnotherapeutic group program in healthy persons with increased levels of perceived stress.

    Authors: Silvia Fisch, Suzana Trivaković-Thiel, Stephanie Roll, Theresa Keller, Sylvia Binting, Margit Cree, Benno Brinkhaus and Michael Teut
    Citation: BMC Complementary Medicine and Therapies 2020 20:344
    Content type: Research article Published on:

  47. Herbal medicines have been a major target for numerous studies through the past years as an alternative treatment for cancer, mainly due to their minimal effects on normal healthy cells. Annona cherimola, popular...

    Authors: Maria Younes, Carl Ammoury, Tony Haykal, Leah Nasr, Rita Sarkis and Sandra Rizk
    Citation: BMC Complementary Medicine and Therapies 2020 20:343
    Content type: Research article Published on:

  48. Multidrug-resistant (MDR) bacteria remain a major cause of morbidity and mortality globally. The present study was designed to investigate the in vitro antibacterial activities of crude methanol extract and co...

    Authors: Marilene M. M. Ambadiang, Brice C. K. Atontsa, Simplice B. Tankeo, Paul Nayim, Brice E. N. Wamba, Gabin T. M. Bitchagno, James D. S. Mpetga, Veronique B. Penlap and Victor Kuete
    Citation: BMC Complementary Medicine and Therapies 2020 20:342
    Content type: Research article Published on:

  49. Herba Siegesbeckiae (HS), the dried aerial parts of Siegesbeckia orientalis L., S. pubescens Makino, or S. glabrescens Makino, is traditionally used for treating chronic diseases in China. However, there is no in...

    Authors: Jia-Ying Wu, Yuen-Cheung Chan, Hui Guo, Ying-Jie Chen, Yu-Xi Liu, Hua Yi and Zhi-Ling Yu
    Citation: BMC Complementary Medicine and Therapies 2020 20:341
    Content type: Research article Published on:

  50. Hericium erinaceus is a culinary and medicinal mushroom in Traditional Chinese Medicines. It has numerous pharmacological effects including immunomodulatory, anti-tumour, anti-microbial, anti-aging and stimulatio...

    Authors: Sze Yuen Lew, Siew Huah Lim, Lee Wei Lim and Kah Hui Wong
    Citation: BMC Complementary Medicine and Therapies 2020 20:340
    Content type: Research article Published on:
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ISSN: 2662-7671

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