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  1. According to recent evidence, psychobiotics exert beneficial effects on central nervous system-related diseases, such as mental disorders. Lactobacillus plantarum PS128 (PS128), a novel psychobiotic strain, impro...

    Authors: Hei-Jen Huang, Jie-Ling Chen, Jian-Fu Liao, Yu-Hsin Chen, Min-Wei Chieu, Ya-Yun Ke, Chih-Chieh Hsu, Ying-Chieh Tsai and Hsiu Mei Hsieh-Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:259
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:136

  2. Buchholzia coriacea Engl. is popularly called wonderful cola due to its wide ethnomedicinal use for the treatment of various ailments. We investigated the possible cytotoxic effect of its various fractions on hu...

    Authors: Hope Onohuean, Rahmat Adetutu Adisa and Abdullateef Isiaka Alagbonsi
    Citation: BMC Complementary Medicine and Therapies 2021 21:258
    Content type: Research Published on:

  3. Oxidative stress-induced injury during hypothermic preservation is a universal problem that delays graft function and decrease the success of organ transplantation. Tanshinone IIA (Tan IIA) was reported to exh...

    Authors: Linhao Xu, Yizhou Xu, Zhoujing Zhu, Huiquan Gu, Chaofeng Chen and Jian Chen
    Citation: BMC Complementary Medicine and Therapies 2021 21:257
    Content type: Research Published on:

  4. Microbial resistance, diabetes mellitus, and obesity are global health care problems that have posed a serious threat to both human and environmental ecosystems. The goals of the present investigations are to ...

    Authors: Nidal Jaradat, Mohammad Qadi, Iyad Ali, Fatima Hussein, Linda Issa, Doaa Rashdan, Manal Jamoos, Re’as Najem, Abdulraziq Zarour and Mohammad Arar
    Citation: BMC Complementary Medicine and Therapies 2021 21:256
    Content type: Research Published on:

  5. Adipose tissue is a critical regulator of lipid storage and endocrine function. Impairment of the recruitment of new adipocytes in the adipose tissue is associated with ectopic fat accumulation, diabetes and i...

    Authors: Eunbi Koh, Boram Kim and Kyungoh Choi
    Citation: BMC Complementary Medicine and Therapies 2021 21:255
    Content type: Research article Published on:

  6. Eucalyptol is an active compound of eucalyptus essential oil and was reported to have many medical attributes including cytotoxic effect on breast cancer cells. However, it has low solubility in aqueous soluti...

    Authors: Mira Nadiah Mohd Izham, Yazmin Hussin, Nurul Fattin Che Rahim, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah and Noorjahan Banu Alitheen
    Citation: BMC Complementary Medicine and Therapies 2021 21:254
    Content type: Research article Published on:

  7. Episiotomy is the most commonn surgical procedure in midwifery which as any other wounds can cause infection or delay in healing.

    Authors: Elmira Toomari, Sepideh Hajian, Faraz Mojab, Tayebe Omidkhah and Malihe Nasiri
    Citation: BMC Complementary Medicine and Therapies 2021 21:253
    Content type: Research article Published on:

  8. While evidence-based practice (EBP) is widely accepted across healthcare professions, research investigating its implementation in manual therapy professions such as osteopathy is limited. The primary aim of t...

    Authors: Francesco Cerritelli, Alessio Iacopini, Matteo Galli, Oliver P. Thomson, Tobias Sundberg, Matthew J. Leach and Jon Adams
    Citation: BMC Complementary Medicine and Therapies 2021 21:252
    Content type: Research Published on:

  9. Mild cognitive impairment (MCI) is considered an intermediate phase between normal aging and dementia. As the majority of cases of amnestic MCI (aMCI) progress to Alzheimer’s disease (AD), it is considered the...

    Authors: Hee-Yeon Shin, Ha-Ri Kim, Geon-Ho Jahng, Chul Jin, Seungwon Kwon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Chang-Nam Ko and Jung-Mi Park
    Citation: BMC Complementary Medicine and Therapies 2021 21:251
    Content type: Research article Published on:

  10. Complementary and integrative medical procedures (CIM) play an important role in general practice (GP). Consequently, in some countries (e.g. USA, Australia) specific curricula for the integration of CIM compe...

    Authors: Jan Valentini, Carina Klocke, Corina Güthlin and Stefanie Joos
    Citation: BMC Complementary Medicine and Therapies 2021 21:250
    Content type: Research Published on:

  11. More than 80% of the African population depend on traditional medicine as a primary healthcare. Although the African migrant community is increasing in Australia, there is no research documenting if and how Af...

    Authors: Zewdneh Shewamene, Tinashe Dune and Caroline A. Smith
    Citation: BMC Complementary Medicine and Therapies 2021 21:249
    Content type: Research Published on:

  12. Edible oils have proven health benefits in the prevention and treatment of various disorders since the establishment of human era. This study was aimed to appraise neuropharmacological studies on the commonly ...

    Authors: Mater H. Mahnashi, Bandar A. Alyami, Yahya S. Alqahtani, Ali O. Alqarni, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Muhammad Shahid, Umer Rashid and Abdul Sadiq
    Citation: BMC Complementary Medicine and Therapies 2021 21:248
    Content type: Research article Published on:

  13. This study aimed to investigate the prevalence of and the factors associated with the regular use of complementary therapies for Taiwanese patients with systemic lupus erythematosus (SLE).

    Authors: Ming-Chi Lu, Hui-Chin Lo, Hsiu-Hua Chang, Chia-Wen Hsu and Malcolm Koo
    Citation: BMC Complementary Medicine and Therapies 2021 21:247
    Content type: Research article Published on:

  14. Influenza A virus (IAV) infection is a continual threat to the health of animals and humans globally. Consumption of the conventional drugs has shown several side effects and drug resistance. This study was ai...

    Authors: Parvaneh Mehrbod, Hanieh Safari, Zeinab Mollai, Fatemeh Fotouhi, Yasaman Mirfakhraei, Hanieh Entezari, Saied Goodarzi and Zahra Tofighi
    Citation: BMC Complementary Medicine and Therapies 2021 21:246
    Content type: Research article Published on:

  15. Adaptive metabolic response towards a low oxygen environment is essential to maintain rapid tumour proliferation and progression. The vascular network that surrounds the tumour develops an intermittent hypoxic...

    Authors: S. H. Shahruzaman, F. Z. Yusof, S. Maniam, S. Fakurazi and S. Maniam
    Citation: BMC Complementary Medicine and Therapies 2021 21:245
    Content type: Research Published on:

  16. The present study aims to investigate the knowledge, attitude, and performance of Iranian Healthcare Professionals (HP) about Complementary and Alternative Medicine (CAM) modalities.

    Authors: Alireza Jafari, Mohaddeseh Zanganeh, Zahra Kazemi, Elaheh Lael-Monfared and Hadi Tehrani
    Citation: BMC Complementary Medicine and Therapies 2021 21:244
    Content type: Research article Published on:

  17. Quercetin and H19 can promote osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). However, whether quercetin regulates H19 expression to promote osteogenic differentiation of BMSCs is unc...

    Authors: Wei Bian, Shunqiang Xiao, Lei Yang, Jun Chen and Shifang Deng
    Citation: BMC Complementary Medicine and Therapies 2021 21:243
    Content type: Research Published on:

  18. Liquidambaris Fructus (LF) is the infructescence of Liquidambar formosana. In Traditional Chinese Medicine, LF has been used to treat joint pain, a common symptom of arthritis and rheumatism; however, a lack of p...

    Authors: Wen-xuan Li, Ping Qian, Yi-tong Guo, Li Gu, Jessore Jurat, Yang Bai and Dong-fang Zhang
    Citation: BMC Complementary Medicine and Therapies 2021 21:242
    Content type: Research Published on:

  19. Authors: Elaissi Ameur, Moumni Sarra, Derbali Yosra, Khouja Mariem, Abid Nabil, Frederic Lynen and Khouja Mohamed Larbi
    Citation: BMC Complementary Medicine and Therapies 2021 21:241
    Content type: Correction Published on:

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:209

  20. As a prevalent type of cryptogenic fibrotic disease with high mortality, idiopathic pulmonary fibrosis (IPF) still lacks effective therapeutic drugs. The compounds extracted from buds and flowers of Chrysanthemum...

    Authors: Juan Nie, Yanlu Liu, Chaoyue Sun, Jingna Zheng, Baoyi Chen, Jianyi Zhuo, Ziren Su, Xiaoping Lai, Jiannan Chen, Jibiao Zheng and Yucui Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:240
    Content type: Research article Published on:

  21. According to the recent global cancer statistics, breast cancer is the leading cause of deaths among women with 2.3 million new cases globally. Likewise, cervical cancer is also among the leading causes of mor...

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Bandar A. Alyami, Ali O. Alqarni, Farhat Ullah, Abdul Wadood, Abdul Sadiq, Azam Shareef and Muhammad Ayaz
    Citation: BMC Complementary Medicine and Therapies 2021 21:239
    Content type: Research Published on:

  22. This study evaluated the in vitro antioxidant activity and comparison of anti-inflammatory and cytotoxic activity of Harpagopytum zeyheri with diclofenac.

    Authors: Sibonokuhle F. Ncube, Lyndy J. McGaw, Emmanuel Mfotie Njoya, Hilton G. T. Ndagurwa, Peter J. Mundy and Samson Sibanda
    Citation: BMC Complementary Medicine and Therapies 2021 21:238
    Content type: Research Published on:

  23. Vulvovaginal candidiasis (VVC), the second leading cause of genital infection in women of reproductive age, is caused by yeasts of the genus Candida. Treatment is usually empirical and performed with azoles, whic...

    Authors: Aline Lorenzoni Paniágua, Amabel Fernandes Correia, Lívia Custódio Pereira, Bruna Maciel de Alencar, Fabiana Brandão Alves Silva, Rosane Mansan Almeida and Yanna Karla de Medeiros Nóbrega
    Citation: BMC Complementary Medicine and Therapies 2021 21:237
    Content type: Research article Published on:

  24. Globally, 3 billion people suffer from either migraine or tension-type headache disorder over their lifetime. Approximately 50% of American adults suffering from headache or migraine have used complementary an...

    Authors: Jeremy Y. Ng and Christina Hanna
    Citation: BMC Complementary Medicine and Therapies 2021 21:236
    Content type: Research article Published on:

  25. Siraitia grosvenorii (binomial name Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang), also called Arhat Fruit or Monk’s Fruit, is a dried ripe fruit belonging to the Cucurbitaceae Family. S. grosve...

    Authors: Wei Dong, Jia Zeng, Qin Wang, Xin Jiang and Ting Huang
    Citation: BMC Complementary Medicine and Therapies 2021 21:235
    Content type: Research article Published on:

  26. Uvaria chamae (UC) and Olax subscorpioidea (OS) roots are included in traditional anti-cancer remedies and some studies have identified their chemopreventive/chemotherapeutic potential. This study aimed to identi...

    Authors: Temidayo D. Popoola, Stephanie T. Guetchueng, Kenneth J. Ritchie, Olufunsho Awodele, Nicola M. Dempster, Oluyemi Akinloye, Satyajit D. Sarker and Amos A. Fatokun
    Citation: BMC Complementary Medicine and Therapies 2021 21:234
    Content type: Research article Published on:

  27. The global prevalence of diabetes mellitus is projected to reach approximately 700 million by the year 2045, with roughly 90–95% of all diabetes cases being type 2 in nature. Patients with type 2 diabetes mell...

    Authors: Jeremy Y. Ng, Manav Nayeni and Kevin Gilotra
    Citation: BMC Complementary Medicine and Therapies 2021 21:233
    Content type: Research article Published on:

  28. One of the most prevalent complications of chemotherapy and radiotherapy is oral mucositis (OM) and manifests as erythema and ulceration. Curcumin is one of the components of turmeric and possesses anti-inflam...

    Authors: Seyed Javad Kia, Maryam Basirat, Hamid Saeidi Saedi and Seyed Ali Arab
    Citation: BMC Complementary Medicine and Therapies 2021 21:232
    Content type: Research Published on:

  29. Neorautanenia mitis, Hydnora abyssinica, and Senna surattensis are medicinal plants with a variety of traditional uses. In this study, we sought to isolate the bioactive compounds responsible for some of these ac...

    Authors: Christiana J. Dawurung, Minh T. H. Nguyen, Jutharat Pengon, Kanchana Dokladda, Ratchanu Bunyong, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Phuong T. M. Nguyen and Stephen G. Pyne
    Citation: BMC Complementary Medicine and Therapies 2021 21:231
    Content type: Research article Published on:

  30. Little is known about the medical material and practices of tribes in the western border areas of Pakistan. The local population has inhabited this remote and isolated area for centuries, and gained medicinal ...

    Authors: Khalid Ahmad, Mushtaq Ahmad, Franz K. Huber and Caroline S. Weckerle
    Citation: BMC Complementary Medicine and Therapies 2021 21:230
    Content type: Research article Published on:

  31. We previously reported that the tomato glycoalkaloid tomatine inhibited the growth of Trichomonas vaginalis strain G3, Tritrichomonas foetus strain D1, and Tritrichomonas foetus-like strain C1 that cause disease ...

    Authors: Christina C. Tam, Kevin Nguyen, Daniel Nguyen, Sabrina Hamada, Okhun Kwon, Irene Kuang, Steven Gong, Sydney Escobar, Max Liu, Jihwan Kim, Tiffany Hou, Justin Tam, Luisa W. Cheng, Jong H. Kim, Kirkwood M. Land and Mendel Friedman
    Citation: BMC Complementary Medicine and Therapies 2021 21:229
    Content type: Research article Published on:

  32. Traditional Chinese Medicine (TCM) has been a proposed treatment option for ulcerative colitis (UC), however it has been difficult to understand the breadth and depth of evidence as various Chinese medicine th...

    Authors: Yu-Xin Sun, Xiao Wang, Xing Liao, Jing Guo, Wen-Bin Hou, Xin Wang, Jian-Ping Liu and Zhao-Lan Liu
    Citation: BMC Complementary Medicine and Therapies 2021 21:228
    Content type: Research article Published on:

  33. Leucas cephalotes is a common ethnomedicinal plant widely used by traditional healers for the treatment of Malaria and other types of fever. Oleanolic acid and its derivatives have been reported for various types...

    Authors: Sulochana Kaushik, Lalit Dar, Samander Kaushik and Jaya Parkash Yadav
    Citation: BMC Complementary Medicine and Therapies 2021 21:227
    Content type: Research article Published on:

  34. Atopic dermatitis (AD) is a chronic inflammatory skin disease mainly caused by immune stimuli. The current study was conducted to investigate the effects of ROCEN and to compare it with betamethasone (Beta) on...

    Authors: Ramin Goudarzi, Maryam Eskandarynasab, Ahad Muhammadnejad, Ahmad Reza Dehpour and Alireza Partoazar
    Citation: BMC Complementary Medicine and Therapies 2021 21:226
    Content type: Research Published on:

  35. Cisplatin is an outstanding anticancer drug, but its use has been decreased remarkably due to sever nephrotoxicity. R. vesicarius L. is a leafy vegetable that is evident with anti-angeogenic, anti-inflammatory, a...

    Authors: Md. Mahmudul Hasan, Most. Sayla Tasmin, Ahmed M. El-Shehawi, Mona M. Elseehy, Md. Abu Reza and Ariful Haque
    Citation: BMC Complementary Medicine and Therapies 2021 21:225
    Content type: Research Published on:

  36. Oleanolic acid (OA) has multiple pharmaceutical applications including anti-inflammatory activity, but low permeability of the molecule limits its widespread use.

    Authors: Zhiqi Shi, Shugang Pan, Luolin Wang and Sha Li
    Citation: BMC Complementary Medicine and Therapies 2021 21:224
    Content type: Research Published on:

  37. The majority of global population suffer from various functional gastrointestinal disorders. Pugionium cornutum (L.) Gaertn. (PCG) is used to relieve indigestive symptoms in traditional Chinese medicine. However,...

    Authors: Chencan Su, Haoyu Li, Bang Chen, Cong Li, Chunxiao Zhang, Long Xu, Mei Lan and Yehua Shen
    Citation: BMC Complementary Medicine and Therapies 2021 21:223
    Content type: Research Published on:

  38. Increasing attention has been paid to the effect of Epimedium on the nervous system, particularly anti-depression function. In the present study, we applied network pharmacology to introduce a testable hypothesis...

    Authors: Yankai Dong, Bo Tao, Xing Xue, Caixia Feng, Yating Ren, Hengyu Ma, Junli Zhang, Yufang Si, Sisi Zhang, Si Liu, Hui Li, Jiahao Zhou, Ge Li, Zhifei Wang, Juanping Xie and Zhongliang Zhu
    Citation: BMC Complementary Medicine and Therapies 2021 21:222
    Content type: Research article Published on:

  39. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. The aim of this study was to evaluate the effects of hydro-alcoholic extract of spinach (HES) on hepatic and serum measureme...

    Authors: Ali Amirinejad, Ali Saneei Totmaj, Farzaneh Mardali, Azita Hekmatdoost, Hadi Emamat, Majid Safa and Farzad Shidfar
    Citation: BMC Complementary Medicine and Therapies 2021 21:221
    Content type: Research Published on:

  40. ECa 233 is a standardized extract of C. asiatica containing the triterpenoid glycosides, madecassoside to asiaticoside in the ratio of (1.5 ± 0.5):1. Anti-inflammatory activities of ECa 233 have been reported; ho...

    Authors: Supannikar Tawinwung, Dhirarin Junsaeng, Supanut Utthiya and Phisit Khemawoot
    Citation: BMC Complementary Medicine and Therapies 2021 21:220
    Content type: Research Published on:

  42. Obtusofolin is the major active ingredient of Catsia tora L., which possesses the activity of improving eyesight and protecting the optic nerve. Investigation on the interaction of obtusofolin with cytochrome ...

    Authors: Na Liu, Ping Chen, Xiaojun Du, Junxia Sun and Shasha Han
    Citation: BMC Complementary Medicine and Therapies 2021 21:218
    Content type: Research Published on:

  43. Traditional Chinese medicine (TCM) has gained widespread application in treating chronic heart failure (CHF) secondary to coronary heart disease (CHD). However, the sound clinical evidence is still lacking. Co...

    Authors: Jiayuan Hu, Ruijin Qiu, Chengyu Li, Min Li, Qianqian Dai, Shiqi Chen, Chen Zhao and Hongcai Shang
    Citation: BMC Complementary Medicine and Therapies 2021 21:217
    Content type: Research article Published on:

  44. In recent years, an increase in the occurrence of illnesses caused by two clinically- important arboviruses has been reported: Zika virus (ZIKV) and Chikungunya virus (CHIKV). There is no licensed antiviral tr...

    Authors: Laura Milena Monsalve-Escudero, Vanessa Loaiza-Cano, Yina Pájaro-González, Andrés Felipe Oliveros-Díaz, Fredyc Diaz-Castillo, Wiston Quiñones, Sara Robledo and Marlen Martinez-Gutierrez
    Citation: BMC Complementary Medicine and Therapies 2021 21:216
    Content type: Research Published on:

  45. The current study was aimed to investigate the anti-allergic activities of the Umbelliferone (UMB) against the acute Histamine and chronic Picryl chloride (PiCl)-induced allergy in mice. UMB is a coumarin deri...

    Authors: Younas, Ashrafullah Khan, Omer Shehzad, Eun Kyoung Seo, Alev Onder and Salman Khan
    Citation: BMC Complementary Medicine and Therapies 2021 21:215
    Content type: Research article Published on:

  46. The results from clinical trials have revealed that the effects of resveratrol supplementation on bone mineral density (BMD) and bone biomarkers are inconsistent. Our objective was to determine the effects of ...

    Authors: Qiangqiang Li, Guangpu Yang, Hongtao Xu, Shaowen Tang and Wayne Yuk-wai Lee
    Citation: BMC Complementary Medicine and Therapies 2021 21:214
    Content type: Research article Published on:

  47. The use of dietary and herbal supplements (DIHES) is widespread among people with multiple sclerosis (PwMS). PwMS are a highly informed patient group, and they use several types of sources to seek information ...

    Authors: Sofie Bergien, Clara M. Petersen, Marie Lynning, Maria Kristiansen and Lasse Skovgaard
    Citation: BMC Complementary Medicine and Therapies 2021 21:213
    Content type: Research article Published on:

  48. Lycium barbarum polysaccharide (LBP), the most abundant functional component of wolfberry, is considered a potent antioxidant and an anti-ageing substance. This review aims to outline the hallmarks of ageing in t...

    Authors: Junguo Ni, Manting Au, Hangkin Kong, Xinluan Wang and Chunyi Wen
    Citation: BMC Complementary Medicine and Therapies 2021 21:212
    Content type: Research article Published on:

  49. The incidence of application of medicinal herbs during pregnancy has increased significantly among women over the past years; however, the safety and efficacy of medicinal herbs during pregnancy are still unclear...

    Authors: Zahra Karimian, Zohreh Sadat, Bahareh Afshar, Maryam Hasani, Marzieh Araban and Mahbubeh Kafaei-Atrian
    Citation: BMC Complementary Medicine and Therapies 2021 21:211
    Content type: Research Published on:

  50. The popular use of traditional medicine in low-income settings has previously been attributed to poverty, lack of education, and insufficient accessibility to conventional health service. However, in many coun...

    Authors: Mengxin Tan, Yuko Otake, Teisi Tamming, Valerie Akuredusenge, Beatha Uwinama and Fabien Hagenimana
    Citation: BMC Complementary Medicine and Therapies 2021 21:210
    Content type: Research article Published on:
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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