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  1. Eurycoma longifolia (EL) has been shown recently to protect against bone calcium loss in orchidectomised rats, the model for androgen-deficient osteoporosis. The mechanism behind this is unclear but it may be re...

    Authors: Ahmad Nazrun Shuid, Eman El-arabi, Nadia Mohd Effendy, Halimaton Saadiah Abdul Razak, Norliza Muhammad, Norazlina Mohamed and Ima Nirwana Soelaiman
    Citation: BMC Complementary and Alternative Medicine 2012 12:152
  2. The leaves of Caylusea abyssinica (fresen.) Fisch. & Mey. (Resedaceae), a plant widely distributed in East African countries, have been used for management of diabetes mellitus in Ethiopian folklore medicine. How...

    Authors: Wondmagegn Tamiru, Ephrem Engidawork and Kaleab Asres
    Citation: BMC Complementary and Alternative Medicine 2012 12:151
  3. Homeopathy is widely used, and many European physicians practice homeopathy in addition to conventional medicine. Adverse effects in homeopathy are not expected by homeopaths due to the negligible quantities o...

    Authors: Trine Stub, Terje Alræk and Anita Salamonsen
    Citation: BMC Complementary and Alternative Medicine 2012 12:150
  4. Kalanchoe tubiflora (KT) is a succulent plant native to Madagascar, and is commonly used as a medicinal agent in Southern Brazil. The underlying mechanisms of tumor suppression are largely unexplored.

    Authors: Yi-Jen Hsieh, Ming-Yeh Yang, Yann-Lii Leu, Chinpiao Chen, Chin-Fung Wan, Meng-Ya Chang and Chih-Jui Chang
    Citation: BMC Complementary and Alternative Medicine 2012 12:149
  5. There is a need for more Comparative Effectiveness Research (CER) to strengthen the evidence base for clinical and policy decision-making. Effectiveness Guidance Documents (EGD) are targeted to clinical resear...

    Authors: Claudia M Witt, Mikel Aickin, Trini Baca, Dan Cherkin, Mary N Haan, Richard Hammerschlag, Jason Jishun Hao, George A Kaplan, Lixing Lao, Terri McKay, Beverly Pierce, David Riley, Cheryl Ritenbaugh, Kevin Thorpe, Sean Tunis, Jed Weissberg…
    Citation: BMC Complementary and Alternative Medicine 2012 12:148
  6. Common cold is caused by a variety of respiratory viruses. The prevalence in children is high, and it potentially contributes to significant morbidity. Iota-carragenan, a polymer derived from red seaweed, has ...

    Authors: Tamas Fazekas, Philipp Eickhoff, Nathalie Pruckner, Georg Vollnhofer, Gustav Fischmeister, Christopher Diakos, Margit Rauch, Maria Verdianz, Andreas Zoubek, Helmut Gadner and Thomas Lion
    Citation: BMC Complementary and Alternative Medicine 2012 12:147
  7. Traditional Chinese Medicine (TCM) is one of the most popular complementary and alternative medicine modalities worldwide. In Chinese and East Asian societies, TCM plays an active role in the modern health car...

    Authors: Yueh-Hsiang Liao, Cheng-Chieh Lin, Tsai-Chung Li and Jaung-Geng Lin
    Citation: BMC Complementary and Alternative Medicine 2012 12:146
  8. Obesity is recognized as a social problem, associated with serious health risks and increased mortality. Numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to...

    Authors: Neerja Rani, Neeru Vasudeva and Surendra Kumar Sharma
    Citation: BMC Complementary and Alternative Medicine 2012 12:145
  9. The 70% methanol extract of Terminalia chebula Retz. fruit (TCME) was investigated for its in vitro iron chelating property and in vivo ameliorating effect on hepatic injury of iron overloaded mice.

    Authors: Rhitajit Sarkar, Bibhabasu Hazra and Nripendranath Mandal
    Citation: BMC Complementary and Alternative Medicine 2012 12:144
  10. The molecular mechanisms of dietary oils (such as fish oil) and unsaturated fatty acids, which are widely used by the public for anti-inflammation and vascular protection, have not been settled yet. In this st...

    Authors: Diana Ruan and Shui-Ping So
    Citation: BMC Complementary and Alternative Medicine 2012 12:143
  11. Methanolic extracts of Gracilaria tenuistipitata (MEGT) were obtained from the edible red algae. Previously, we found that water extract of G. tenuistipitata was able to modulate oxidative stress-induced DNA dama...

    Authors: Chi-Chen Yeh, Jing-Iong Yang, Jin-Ching Lee, Chao-Neng Tseng, Ya-Ching Chan, You-Cheng Hseu, Jen-Yang Tang, Li-Yeh Chuang, Hurng-Wern Huang, Fang-Rong Chang and Hsueh-Wei Chang
    Citation: BMC Complementary and Alternative Medicine 2012 12:142
  12. The improvement of axonal regeneration is a major objective in the treatment of peripheral nerve injuries. The aim of this study was to evaluate the effects of electro-acupuncture on the functional recovery of...

    Authors: Ngoc Son Hoang, Chamroeun Sar, Jean Valmier, Victor Sieso and Frédérique Scamps
    Citation: BMC Complementary and Alternative Medicine 2012 12:141
  13. In ancient times, plants were recognized for their medicinal properties. Later, the arrival of synthetic drugs pushed it to the backstage. However, from being merely used for food, plants are now been widely e...

    Authors: Xavier Lieben Louis, Ryan Murphy, Sijo Joseph Thandapilly, Liping Yu and Thomas Netticadan
    Citation: BMC Complementary and Alternative Medicine 2012 12:140
  14. Harpalycin 2 (HP-2) is an isoflavone isolated from the leaves of Harpalyce brasiliana Benth., a snakeroot found in northeast region of Brazil and used in folk medicine to treat snakebite. Its leaves are said to b...

    Authors: Rafael M Ximenes, Renata S Alves, Ticiana P Pereira, Renata M Araújo, Edilberto R Silveira, Marcelo M Rabello, Marcelo Z Hernandes, Veronica C G Soares, Daniel Bristot, Camila L Pires, Daniela O Toyama, Henrique H Gaeta, Helena S A Monteiro and Marcos H Toyama
    Citation: BMC Complementary and Alternative Medicine 2012 12:139
  15. Doxorubicin (DOX) is an effective antineoplastic drug; however, clinical use of DOX is limited by its dose-dependent cardiotoxicity. It is well known that reactive oxygen species (ROS) play a vital role in the...

    Authors: Wen-Ching Wang, Yih-Huei Uen, Ming-Long Chang, Khoot-Peng Cheah, Joe-Sharg Li, Wen-Yu Yu, Kock-Chee Lee, Cheuk-Sing Choy and Chien-Ming Hu
    Citation: BMC Complementary and Alternative Medicine 2012 12:138
  16. This study was to explore the effects of Gan-Lu-Yin (GLY) on the migration of vascular smooth muscle cells (VSMCs) induced by fetal bovine serum and on neointima formation in a rat model of carotid artery ball...

    Authors: Yi-Chung Chien, Ming-Jyh Sheu, Chieh-Hsi Wu, Wen-Hsin Lin, Ying-Yi Chen, Po-Liang Cheng and Hsu-Chen Cheng
    Citation: BMC Complementary and Alternative Medicine 2012 12:137
  17. Psorospermun aurantiacum and Hypericum lanceolatum are plants locally used in Cameroon and other parts of Africa for the treatment of gastrointestinal and urinary tract infections, skin infections, venereal dise...

    Authors: Patricia D Tchakam, Paul K Lunga, Théodora K Kowa, Antoine Honoré N Lonfouo, Hippolyte K Wabo, Léon A Tapondjou, Pierre Tane and Jules-Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2012 12:136
  18. In this report, the isorhamnetin 3-o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, were evaluated for their ability to induce antioxidant and antigenotoxic effect...

    Authors: Jihed Boubaker, Mohammed Ben Sghaier, Ines Skandrani, Kamel Ghedira and Leila Chekir-Ghedira
    Citation: BMC Complementary and Alternative Medicine 2012 12:135
  19. Our previous study had shown that P. amaryllifolius was able to selectively inhibit cell proliferation of hormone independent breast cancer cell line MDA-MB-231. To understand the mode of killing and mechanism of...

    Authors: Hueh Zan Chong, Swee Keong Yeap, Asmah Rahmat, Abdah Md Akim, Noorjahan Banu Alitheen, Fauziah Othman and Cheng Lian Gwendoline-Ee
    Citation: BMC Complementary and Alternative Medicine 2012 12:134
  20. Despite high levels of clinically significant persistent cancer related fatigue in breast cancer survivors few treatments are currently available and most pose a significant burden on the part of the woman. Ac...

    Authors: Suzanna Maria Zick, Gwen Karilyn Wyatt, Susan Lynn Murphy, J Todd Arnedt, Ananda Sen and Richard Edmund Harris
    Citation: BMC Complementary and Alternative Medicine 2012 12:132
  21. As complementary and alternative medicine (CAM) has developed extensively, uncertainty about the appropriateness of the terms CAM and other CAM-related terms has grown both in the research and practice communi...

    Authors: Isabelle Gaboury, Karine Toupin April and Marja Verhoef
    Citation: BMC Complementary and Alternative Medicine 2012 12:131
  22. Utilization of herbal medicines in the preoperative period by Nigerian patients booked for day case surgery has not been explored.

    Authors: Tonia C Onyeka, Humphrey A Ezike, Ogochukwu M Nwoke, Emeka A Onyia, Elias C Onuorah, Samson U Anya and Timothy E Nnacheta
    Citation: BMC Complementary and Alternative Medicine 2012 12:130
  23. Complementary and alternative medicine (CAM) is widely used for the treatment of infertility. While the Middle East and North Africa region has been shown to house one of the fastest growing markets of CAM pro...

    Authors: Ghina S Ghazeeri, Johnny T Awwad, Mohamad Alameddine, Zeina MH Younes and Farah Naja
    Citation: BMC Complementary and Alternative Medicine 2012 12:129
  24. The leaves of Leea indica (Vitaceae), commonly known as ‘Huo Tong Shu’ in Malaysia, have been traditionally used as natural remedy in folk medicine by the locals. The current study reports the outcome of antioxid...

    Authors: Nidyaletchmy Subba Reddy, Suerialoasan Navanesan, Saravana Kumar Sinniah, Norhanom Abdul Wahab and Kae Shin Sim
    Citation: BMC Complementary and Alternative Medicine 2012 12:128
  25. In Traditional Chinese Medicine (TCM), the lip diagnosis is an important diagnostic method which has a long history and is applied widely. The lip color of a person is considered as a symptom to reflect the ph...

    Authors: FuFeng Li, Changbo Zhao, Zheng Xia, Yiqin Wang, Xiaobo Zhou and Guo-Zheng Li
    Citation: BMC Complementary and Alternative Medicine 2012 12:127
  26. Various medications of natural origin have effectively treated stress-related disorders, such as sleep disturbances and agitated conditions. The efficacy of Neurexan, a multicomponent, low-dose medication, has...

    Authors: Wilfried Dimpfel, Kerstin Roeska and Bernd Seilheimer
    Citation: BMC Complementary and Alternative Medicine 2012 12:126
  27. Staphylococcus aureus is the pathogen most often and prevalently involved in skin and soft tissue infections. In recent decades outbreaks of methicillin-resistant S. aureus (MRSA) have created major problems for...

    Authors: Arunachalam Muthaiyan, Debabrata Biswas, Philip G Crandall, Brian J Wilkinson and Steven C Ricke
    Citation: BMC Complementary and Alternative Medicine 2012 12:125
  28. A common side effect of oxaliplatin is peripheral neurotoxicity. Oxidative stress to dorsal root ganglion (DRG) may be one of important pathogenic mechanisms. Green tea contains four polyphenol catechins, whic...

    Authors: Jung Soo Lee, Yoon Tae Kim, Eun Kyoung Jeon, Hye Sung Won, Young-Seok Cho and Yoon Ho Ko
    Citation: BMC Complementary and Alternative Medicine 2012 12:124
  29. In the field of acupuncture research, the topic of acupoint specificity has received increasing attention, but no unified conclusion has been reached on whether or not acupoint specificity exists. Furthermore,...

    Authors: Jie Yang, Fang Zeng, Yue Feng, Li Fang, Wei Qin, Xuguang Liu, Wenzhong Song, Hongjun Xie, Ji Chen and Fanrong Liang
    Citation: BMC Complementary and Alternative Medicine 2012 12:123
  30. Appetite is intricately connected to eating behaviors and shows a high individual variability. In an attempt to approach the problem of gut hormone profiles, appetite, and eating behaviors at the individual le...

    Authors: Junhee Lee, Jiwon Lee, Hyunshang Shin, Ki-Suk Kim, Euiju Lee, Byunghee Koh and Hyeung-Jin Jang
    Citation: BMC Complementary and Alternative Medicine 2012 12:122
  31. Sida acuta Burn f. and Sida cordifolia L. (Malvaceae) are traditionally used in Burkina Faso to treat several ailments, mainly pains, including abdominal infections and associated diseases. Despite the extensive...

    Authors: Kiessoun Konaté, Imaël Henri Nestor Bassolé, Adama Hilou, Raïssa RR Aworet-Samseny, Alain Souza, Nicolas Barro, Mamoudou H Dicko, Jacques Y Datté and Bertrand M’Batchi
    Citation: BMC Complementary and Alternative Medicine 2012 12:120
  32. The fungus of Ganoderma is a traditional medicine in Asia with a variety of pharmacological functions including anti-cancer activities. We have purified an extracellular heteropolysaccharide fraction, PS-F2, from...

    Authors: Cheng-Li Wang, Chiu-Ying Lu, Chia-Chen Pi, Yu-Jing Zhuang, Ching-Liang Chu, Wen-Hsiung Liu and Chun-Jen Chen
    Citation: BMC Complementary and Alternative Medicine 2012 12:119
  33. TS-1 is an oral anticancer drug containing a 5-fluorouracil derivative (Tegafur) that is widely used in Japan for the treatment of cancer, especially gastrointestinal tumors. Frequently, however, TS-1 therapy ...

    Authors: Kazuo Ogawa, Tatsushi Omatsu, Chinami Matsumoto, Naoko Tsuchiya, Masahiro Yamamoto, Yuji Naito and Toshikazu Yoshikawa
    Citation: BMC Complementary and Alternative Medicine 2012 12:118
  34. In the present study, we examined the antioxidant effect of water soluble derivative of propolis (WSDP) and ethanolic (EEP) extract of propolis on renal and liver function in alloxan-induced diabetic mice. In ...

    Authors: Nada Oršolić, Damir Sirovina, Marijana Zovko Končić, Gordana Lacković and Gordana Gregorović
    Citation: BMC Complementary and Alternative Medicine 2012 12:117
  35. Arctium lappa L. (Asteraceae), burdock, is a medicinal plant that is popularly used for treating hypertension, gout, hepatitis, and other inflammatory disorders. This study was performed to test the effect of et...

    Authors: Yun Jung Lee, Deok Ho Choi, Guk Hyun Cho, Jin Sook Kim, Dae Gill Kang and Ho Sub Lee
    Citation: BMC Complementary and Alternative Medicine 2012 12:116
  36. This study aims to examine knowledge and attitudes towards Complementary and Alternative Medicine among medical students in Turkey, and find out whether they want to be trained in Complementary and Alternative...

    Authors: Hulya Akan, Guldal Izbirak, Elif Çiğdem Kaspar, Çiğdem Apaydin Kaya, Serpil Aydin, Nejat Demircan, P Gamze Bucaktepe, Cahit Özer, Hüseyin A Sahin and Osman Hayran
    Citation: BMC Complementary and Alternative Medicine 2012 12:115
  37. Launaea procumbens (Asteraceae) is used as a folk medicine to treat hepatic disorders in Pakistan. The effect of a chloroform extract of Launaea procumbens (LPCE) was evaluated against carbon-tetrachloride (CCl4

    Authors: Rahmat A Khan, Muhammad R Khan, Mushtaq Ahmed, Sumaira Sahreen, Naseer A Shah, Mir Sadiq Shah, Jasia Bokhari, Umbreen Rashid, Bushra Ahmad and Shumaila Jan
    Citation: BMC Complementary and Alternative Medicine 2012 12:114
  38. Ayurveda, the traditional Indian system of medicine has given great emphasis to the promotion of health. Rasayana is one of the eight branches of Ayurveda which refers to rejuvenant therapy. It has been report...

    Authors: Kanive Parashiva Guruprasad, Advait Subramanian, Vikram Jeet Singh, Raghavendra Sudheer Kumar Sharma, Puthiya Mundyat Gopinath, Vikash Sewram, Panniyampilly Madhavankutty Varier and Kapaettu Satyamoorthy
    Citation: BMC Complementary and Alternative Medicine 2012 12:113
  39. Traditional Chinese medicine (TCM) is a widely applied complementary therapy for cancer patients. It can reduce the chemical drugs induced toxic effects to improve the quality of life (QOL). This study applies...

    Authors: Ling Xu, HeGen Li, ZhenYe Xu, ZhongQi Wang, LingShuang Liu, JianHui Tian, JianLi Sun, Lei Zhou, YiLin Yao, LiJing Jiao, Wan Su, HuiRu Guo, PeiQi Chen and JiaXiang Liu
    Citation: BMC Complementary and Alternative Medicine 2012 12:112
  40. Cis-Platinum (II) (cis-diammine dichloroplatinum; CDDP) is a potent antitumor compound widely used for the treatment of many malignancies. An important side-effect of CDDP is nephrotoxicity. The cytotoxic acti...

    Authors: Dalel Brahmi, Yousra Ayed, Mbarka Hfaiedh, Chayma Bouaziz, Hedi Ben Mansour, Lazhar Zourgui and Hassen Bacha
    Citation: BMC Complementary and Alternative Medicine 2012 12:111
  41. Plant-based foods have been used in traditional health systems to treat diabetes mellitus. The successful prevention of the onset of diabetes consists in controlling postprandial hyperglycemia by the inhibitio...

    Authors: Sirichai Adisakwattana, Thanyachanok Ruengsamran, Patcharaporn Kampa and Weerachat Sompong
    Citation: BMC Complementary and Alternative Medicine 2012 12:110
  42. The aim of this study was to determine the presence and the intensity of humoral immunity to melanoma-associated antigens: tyrosinase and melanin, in patients with melanoma, in persons with vitiligo and in con...

    Authors: Marija Đorđić, Ivana Z Matić, Ivana Filipović-Lješković, Radan Džodić, Miomir Šašić, Aleksandra Erić-Nikolić, Ana Vuletić, Branka Kolundžija, Ana Damjanović, Nađa Grozdanić, Srđan Nikolić, Janko Pralica, Danijela Dobrosavljević, Sanvila Rašković, Slađana Andrejević and Zorica Juranić
    Citation: BMC Complementary and Alternative Medicine 2012 12:109
  43. Mineral water from deep-sea bedrock, formed over thousands of years, is rich in minerals such as Ca, Mg, Na, K, Fe and others. Our present study was to investigate the preventive effects of natural deep-sea wa...

    Authors: Jong-Phil Bak, Yong-Min Kim, Jeonghyun Son, Chang-Ju Kim and Ee-Hwa Kim
    Citation: BMC Complementary and Alternative Medicine 2012 12:108
  44. Ribosome-inactivating proteins (RIP) have been studied in the search for toxins that could be used as immunotoxins for cancer treatment. Pulchellin, a type 2 RIP, is suggested to induce immune responses that h...

    Authors: Djamile Cordeiro de Matos, Lívia Carolina Abreu de Ribeiro, Aline Tansini, Lucas Souza Ferreira, Marisa Campos Polesi Placeres, Lucas Luis Colombo and Iracilda Zeppone Carlos
    Citation: BMC Complementary and Alternative Medicine 2012 12:107
  45. The skin is chronically exposed to endogenous and environmental pro-oxidant agents, leading to the harmful generation of reactive oxygen species. Antioxidant is vital substances which possess the ability to pr...

    Authors: Jamnian Chompoo, Atul Upadhyay, Masakazu Fukuta and Shinkichi Tawata
    Citation: BMC Complementary and Alternative Medicine 2012 12:106
  46. Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of p...

    Authors: Robert M Littleton, Matthew Miller and Jay R Hove
    Citation: BMC Complementary and Alternative Medicine 2012 12:105
  47. Xanthones are a group of oxygen-containing heterocyclic compounds with remarkable pharmacological effects such as anti-cancer, antioxidant, anti-inflammatory, and antimicrobial activities.

    Authors: Abdalrahim F A Aisha, Khalid M Abu-Salah, Zhari Ismail and Amin Malik Shah Abdul Majid
    Citation: BMC Complementary Medicine and Therapies 2012 12:104
  48. The efficacy of Centella asiatica for incision and burn wounds are not fully understood. Here, we report the wound healing activities of sequential hexane, ethyl acetate, methanol, and water extracts of Centella ...

    Authors: Juraiporn Somboonwong, Mattana Kankaisre, Boonyong Tantisira and Mayuree H Tantisira
    Citation: BMC Complementary and Alternative Medicine 2012 12:103