Table 1 Cytotoxic activity (IC₅₀ values) of the crude extract, fractions, and certain compounds of DP via MTT assay against HCT-116, MCF-7, and HepG-2

n-Hexane fraction

85.4 ± 2.6

113 ± 2.7

60.1 ± 2.8

DCM fraction

111 ± 3.1

230 ± 4.2

170 ± 4.9

EtOAc fraction

59.9 ± 1.2

166 ± 3.9

42.2 ± 2.1

Aqueous fraction

> 500

> 500

> 500

1

-

-

106.39 ± 3.12

2

-

-

356.92 ± 10.27

7

-

-

14.38 ± 0.69

11

-

-

82.98 ± 4.06

12

-

-

47.93 ± 2.64

13

-

-

15.39±0.95

Vinblastine sulfate

2.30 ± 0.35

3.59 ± 0.43

3.01 ± 0.24