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Retraction Note: Suppression of NF-κB signaling by ECN in an arthritic model of inflammation

The Original Article was published on 13 June 2022

Retraction Note: BMC Complement Med Ther 22, 158 (2022)

The Editor has retracted this article. After publication, concerns were raised regarding image similarities among the panels in Fig. 8. Specifically:

  • The p-JNK ENC image appears to overlap with p-JNK Dexa;

  • The NF-κB Normal control appears to overlap with NF-κB ECN.

Additionally, Fig. 8 TNF-a Dexa and ECN images appear to overlap with Fig. 13 TNF-a NCHDH and CFA in [1], respectively.

The authors have provided the raw data to address these concerns. However, further checks by the Publisher identified numerous irregularities in the raw data, and further cases of data overlap with [1]. The Editor therefore no longer has confidence in the presented data.

Salman Khan does not agree to this retraction. None of the other authors have responded to any correspondence from the editor or publisher about this retraction.


  1. Khan AU, Khan A, Khan A, et al. Inhibition of NF-κB signaling and HSP70/HSP90 proteins by newly synthesized hydrazide derivatives in arthritis model. Naunyn-Schmiedeberg's Arch Pharmacol. 2021;394:1497–519.

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Correspondence to Feng Wang or Salman Khan.

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Khan, A., Zhang, L., Li, C.H. et al. Retraction Note: Suppression of NF-κB signaling by ECN in an arthritic model of inflammation. BMC Complement Med Ther 23, 127 (2023).

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