Skip to main content

Table 1 Studies included in the systematic review

From: Wrist-ankle acupuncture has a positive effect on cancer pain: a meta-analysis

Author, year Sample Age Gender Cancer type The intervention for treatment group The intervention for control group Outcome indicator Adverse reactions (%)
Shen, 2000 [19] ADG: 34
CG: 31
ADG: 24–76
CG: 32–68
ADG:female 3
male 31
CG: female 3
male 28
Mixed WAA + drug Grade II pain: weak opioid analgesics plus adjuvants
Grade III pain: strong opioid analgesics plus adjuvants
Pain relief rate Not reported
Hu, 2004 [20] Moderate pain group
AG: 20
CG I: 20
Severe pain group
AG: 16
CG II: 20
ADG: 18
Moderate pain group
AG:48.9 ± 13.0
CG I:49.7 ± 13.5
Severe pain group
AG: 48.3 ± 7.9
CG II:51.1 ± 8.9
ADG:53.6 ± 11.3
Moderate pain group
AG:female 2
male 18
CG I:female 3
male 17
Severe pain group
AG: female 2
male 14
CG II:female 3
male 17
ADG:female 0
male 18
Liver cancer WAA/ WAA + drug CG I: weak opioids (Such as codeine)
CGII: morphine sulfate sustained-release tablets as a representative treatment
Pain relief rate; NRS ADG: 3(16.7)
CG II: 12(60)
Han, 2012 [21] AG:25
CG:25
AG:20–71
CG:19–73
AG:female 8
male 17
CG:female 6
male 19
Liver cancer WAA Three-step drug analgesia Pain relief rate AG: 2 (8)
CG: 19 (76)
Author, year Sample Age Gender Cancer type The intervention for treatment group The intervention for control group Outcome indicator Adverse reactions (%)
Zeng, 2014 [22] AG:30
CG:30
AG:53.8 ± 12.8
CG:49.0 ± 14.1
AG:female 3
male 27
CG:female 2
male 28
Liver cancer WAA A single dose of morphine sulfate 10 mg Pain relief rate Unclear
Dong, 2015 [23] AG:49
CG:36
ADG:41
AG:61 ± 13
CG:59 ± 12
ADG:63 ± 11
AG:female 16
male 33
CG:female 13
male 23
ADG:female 14
male 27
Liver cancer WAA / WAA + drug Three-step drug analgesia Pain relief rate AG:12(24.5)
CG:35(97.2)
ADG:39(95.1)
Wang, 2017 [24] AG:20
CG:20
ADG:20
19–81 Female 25
male 35
Mixed WAA / WAA + drug Three-step drug analgesia Pain relief rate AG: 2 (10)
CG: 12 (60)
ADG: 6 (30)
Dong, 2018 [25] ADG: 60
CG: 60
47.65 ± 22.41 Female 41
male 79
Mixed WAA + drug Strong opioid analgesia Pain relief rate; NRS ADG:35(58.3)
CG: 45 (75)
Zhang, 2018 [26] ADG: 76
CG: 34
ADG: 46–69
CG: 45–75
ADG: female 26
male 50
CG: female 13
male 21
Gastric cancer WAA + drug Drug therapy Pain relief rate Not reported
Su, 2018 [27] AG: 40
CG: 40
76.6 ± 2.5 Not reported Bone metasta- sis of prostate cancer WAA Drug therapy VAS 2(2.5)
Author, year Sample Age Gender Cancer type The intervention for treatment group The intervention for control group Outcome indicator Adverse reactions (%)
Fu, 2019 [28] ADG: 18
CG: 18
ADG: 66 ± 12
CG: 64 ± 15
ADG: female 8
male 10
CG: female 8
male 10
Mixed WAA + drug Morphine sustained release tablets Pain relief rate; NRS ADG:3(18.75)
CG: 9(56.25)
Luan, 2019 [29] ADG: 32
CG: 33
ADG: 31–70
CG: 44–68
ADG:female 15
male 17
CG: female 13
male 20
Mixed WAA + drug Opioid analgesics Pain relief rate Not reported
Wu, 2019 [30] ADG: 30
CG: 30
ADG: 56 ± 3
CG: 58 ± 3
ADG:female 15
male 15
CG: female 14
male 16
Mixed WAA + drug Three-step drug analgesia Pain relief rate; VAS ≥ grade III:
ADG: 0(0)
CG: 6(20)
Xu, 2020 [31] ADG: 39
CG: 40
ADG:64.9 ± 11.0
CG:67.33 ± 13.1
ADG:female 21
male 18
CG: female 16
male 24
Mixed WAA+ drug Three-step drug analgesia Pain relief rate Not reported
  1. Note: AG Acupuncture Group (The acupuncture intervention is wrist-ankle acupuncture), ADG Acupuncture + Drug Group (The acupuncture intervention is wrist-ankle acupuncture; The drug treatment is the same as the control group), CG Control Group, WAA Wrist-Ankle Acupuncture, NRS Numerical Rating Scale, VAS Visual Analogue Scale