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Table 7 Parasitemia and survival time of infected mice treated with solvent fractions of the leaves of Olea europaea in the 4-day suppressive test

From: Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

Groups % Parasitemia % Suppression Survival time (days)
2% TW80 37.84 ± 0.51 7.33 ± 0.21
CQ25 mg/kg 0.00 ± 0.00 100.00a3 28.00 ± 0.00a3
200 mg/kg CF 25.92 ± 0.25 31.52a3b3d2e3 10.17 ± 0.31a3b3e1
400 mg/kg CF 24.17 ± 0.24 36.12a3b3 10.83 ± 0.33a3b3
600 mg/kg CF 23.45 ± 0.13 38.03a3b3 11.17 ± 0.17a3b3
2% TW80 38.01 ± 0.61 7.17 ± .017
CQ25 mg/kg 0.00 ± 0.00 100.00a3 28.00 ± 0.00a3
200 mg/kg BF 22.55 ± 0.28 40.68a3b3d2e3 11.33 ± 0.33a3b3d1e3
400 mg/kg BF 20.44 ± 0.45 46.23a3b3e1 12.67 ± 0.33a3b3e1
600 mg/kg BF 18.77 ± 0.22 50.63a3b3 13.83 ± 0.31a3b3
2% TW80 37.86 ± 0.51 7.17 ± 0.17
CQ25 mg/kg 0.00 ± 0.00 100.00a3 28.00 ± 0.00a3
200 mg/kg AF 31.25 ± 0.78 17.46a3b3e1 8.83 ± 0.17a3b3e1
400 mg/kg AF 30.34 ± 0.26 19.86a3b3 9.50 ± 0.22a3b3
600 mg/kg AF 30.03 ± 0.27 20.67a3b3 9.83 ± 0.17a3b3
  1. Data are expressed as mean ± SEM; n = 6; CF, chloroform fraction; BF, butanol fraction; AF, aqueous fraction; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine