Quigley HA: Number of people with glaucoma worldwide. Br J Ophthalmol. 1996, 80 (5): 389-393. 10.1136/bjo.80.5.389.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sommer A: Intraocular pressure and glaucoma. Am J Ophthalmol. 1989, 107 (2): 186-188.
Article
CAS
PubMed
Google Scholar
Quigley HA: Open-angle glaucoma. N Engl J Med. 1993, 328 (15): 1097-1106. 10.1056/NEJM199304153281507.
Article
CAS
PubMed
Google Scholar
Izzotti A, Saccà SC, Longobardi M, Cartiglia C: Sensitivity of ocular anterior chamber tissues to oxidative damage and its relevance to the pathogenesis of glaucoma. Invest Ophthalmol Vis Sci. 2009, 50 (11): 5251-5258. 10.1167/iovs.09-3871.
Article
PubMed
Google Scholar
Majsterek I, Malinowska K, Stanczyk M, Kowalski M, Blaszczyk J, Kurowska AK, Kaminska A, Szaflik J, Szaflik JP: Evaluation of oxidative stress markers in pathogenesis of primary open-angle glaucoma. Exp Mol Pathol. 2011, 90 (2): 231-237. 10.1016/j.yexmp.2011.01.001.
Article
CAS
PubMed
Google Scholar
Erdurmuş M, Yağcı R, Atış Ö, Karadağ R, Akbaş A, Hepşen IF: Antioxidant status and oxidative stress in primary open angle glaucoma and pseudoexfoliative glaucoma. Curr Eye Res. 2011, 36 (8): 713-718. 10.3109/02713683.2011.584370.
Article
PubMed
Google Scholar
Izzotti A, Bagnis A, Saccà SC: The role of oxidative stress in glaucoma. Mutat Res. 2006, 612 (2): 105-114. 10.1016/j.mrrev.2005.11.001.
Article
CAS
PubMed
Google Scholar
Ferreira SM, Lerner SF, Brunzini R, Evelson PA, Llesuy SF: Oxidative stress markers in aqueous humor of glaucoma patients. Am J Ophthalmol. 2004, 137 (1): 62-69. 10.1016/S0002-9394(03)00788-8.
Article
CAS
PubMed
Google Scholar
Jia LY, Sun L, Fan DS, Lam DS, Pang CP, Yam GH: Effect of topical Ginkgo biloba extract on steroid-induced changes in the trabecular meshwork and intraocular pressure. Arch Ophthalmol. 2008, 126 (12): 1700-1706. 10.1001/archophthalmol.2008.512.
Article
PubMed
Google Scholar
Assimopoulou AN, Sinakos Z, Papageorgiou VP: Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents. Phytother Res. 2005, 19 (11): 997-1000. 10.1002/ptr.1749.
Article
CAS
PubMed
Google Scholar
Ochiai T, Shimeno H, Mishima K, Iwasaki K, Fujiwara M, Tanaka H, Shoyama Y, Toda A, Eyanagi R, Soeda S: Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo. Biochim Biophys Acta. 2007, 1770 (4): 578-584. 10.1016/j.bbagen.2006.11.012.
Article
CAS
PubMed
Google Scholar
Hosseinzadeh H, Sadeghnia HR, Ziaee T, Danaee A: Protective effect of aqueous saffron extract (Crocus sativus L.) and crocin, its active constituent, on renal ischemia reperfusion- induced oxidative damage in rats. J Pharm Pharm Sci. 2005, 8 (3): 387-393.
CAS
PubMed
Google Scholar
Bolhassani A, Khavari A, Bathaie SZ: Saffron and natural carotenoids: Biochemical activities and anti-tumor effects. Biochim Biophys Acta. 2014, 1845 (1): 20-30.
CAS
PubMed
Google Scholar
Shahmansouri N, Farokhnia M, Abbasi SH, Kassaian SE, Noorbala Tafti AA, Gougol A, Yekehtaz H, Forghani S, Mahmoodian M, Saroukhani S, Arjmandi-Beglar A, Akhondzadeh S: A randomized, double-blind, clinical trial comparing the efficacy and safety of Crocus sativus L. with fluoxetine for improving mild to moderate depression in post percutaneous coronary intervention patients. J Affect Disord. 2014, 155: 216-222.
Article
CAS
PubMed
Google Scholar
Makri OE, Ferlemi AV, Lamari FN, Georgakopoulos CD: Saffron administration prevents selenite-induced cataractogenesis. Mol Vis. 2013, 19: 1188-1197.
CAS
PubMed
PubMed Central
Google Scholar
Age-Related Eye Disease Study Group: A randomized, placebo- controlled, clinical trial of high-dose supplements with vitamins C and E, beta-carotene, and zinc for age related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001, 119 (10): 1417-1436.
Article
Google Scholar
Ravindran RD, Vashist P, Gupta SK, Young IS, Maraini G, Camparini M, Jayanthi R, John N, Fitzpatrick KE, Chakravarthy U, Ravilla TD, Fletcher AE: Inverse association of vitamin C with cataract in older people in India. Ophthalmology. 2011, 118 (10): 1958-1965. 10.1016/j.ophtha.2011.03.016.
Article
PubMed
PubMed Central
Google Scholar
Izzotti A, Saccà SC, Longobardi M, Cartiglia C: Mitochondrial damage in the trabecular meshwork of patients with glaucoma. Arch Ophthalmol. 2010, 128 (6): 724-730. 10.1001/archophthalmol.2010.87.
Article
CAS
PubMed
Google Scholar
Saccà SC, Izzotti A, Rossi P, Traverso C: Glaucomatous outflow pathway and oxidative stress. Exp Eye Res. 2007, 84 (3): 389-399. 10.1016/j.exer.2006.10.008.
Article
PubMed
Google Scholar
Tezel G, Wax MB: Glial modulation of retinal ganglion cell death in glaucoma. J Glaucoma. 2003, 12 (1): 63-68. 10.1097/00061198-200302000-00014.
Article
PubMed
Google Scholar
Wood JP, Lascaratos G, Bron AJ, Osborne NN: The influence of visible light exposure on cultured RGC-5 cells. Mol Vis. 2007, 14: 334-344.
PubMed Central
Google Scholar
Zhou L, Li Y, Yue BY: Oxidative stress affects cytoskeletal structure and cell-matrix interactions in cells from an ocular tissue: the trabecular meshwork. J Cell Physiol. 1999, 180 (2): 182-189. 10.1002/(SICI)1097-4652(199908)180:2<182::AID-JCP6>3.0.CO;2-X.
Article
CAS
PubMed
Google Scholar
Li AF, Tane N, Roy S: Fibronectin over expression inhibits trabecular meshwork cell monolayer permeability. Mol Vis. 2004, 10: 750-757.
CAS
PubMed
Google Scholar
Maccarone R, Di Marco S, Bisti S: Saffron supplement maintains morphology and function after exposure to damaging light in mammalian retina. Invest Ophthalmol Vis Sci. 2008, 49: 1254-1261. 10.1167/iovs.07-0438.
Article
PubMed
Google Scholar
Eckert A, Keil U, Kressmann S, Schindowski K, Leutner S, Leutz S, Müller WE: Effects of EGb761 Gingko biloba extract on mitochondrial functions and oxidative stress. Pharmacopsychiatry. 2003, 36 (1): S15-S23.
CAS
PubMed
Google Scholar
Takuma K, Hoshina Y, Arai S, Himeno Y, Matsuo A, Funatsu Y, Kitahara Y, Ibi D, Hayase M, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K: Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats. Neuroscience. 2007, 149 (2): 256-262. 10.1016/j.neuroscience.2007.07.042.
Article
CAS
PubMed
Google Scholar
He Y, Leung KW, Zhang YH, Duan S, Zhong XF, Jiang RZ, Peng Z, Tombran-Tink J, Ge J: Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants. Invest Ophthalmol Vis Sci. 2008, 49 (4): 1447-1458. 10.1167/iovs.07-1361.
Article
PubMed
Google Scholar
Chen M, Liu B, Gao Q, Zhuo Y, Ge J: Mitochondria-targeted peptide MTP- 131alleviates mitochondrial dysfunction and oxidative damage in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2011, 1; 52 (10): 7027-7037.
Article
PubMed
Google Scholar
Giaconi JA, Yu F, Stone KL, Pedula KL, Ensrud KE, Cauley JA, Hochberg MC, Coleman AL, Study of Osteoporotic Fractures Research Group: The association of consumption of fruits/vegetables with decreased risk of glaucoma among older African-American women in the study of osteoporotic fractures. Study of Osteoporotic Fractures Research Group. Am J Ophthalmol. 2012, 154 (4): 635-644. 10.1016/j.ajo.2012.03.048.
Article
PubMed
PubMed Central
Google Scholar
Kang JH, Pasquale LR, Willett W, Rosner B, Egan KM, Faberowski N, Hankinson SE: Antioxidant intake and primary open-angle glaucoma: a prospective study. Am J Epidemiol. 2003, 158 (4): 337-346. 10.1093/aje/kwg167.
Article
PubMed
Google Scholar
Schmidt M, Betti G, Hensel A: Saffron in phytotherapy: pharmacology and clinical uses. Wien Med Wochenschr. 2007, 157 (13–14): 315-319.
Article
PubMed
Google Scholar
Akhondzadeh S, Fallah-Pour H, Afkham K, Jamshidi AH, Khalighi-Cigaroudi F: Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. BMC Complement Altern Med. 2004, 4: 12-10.1186/1472-6882-4-12.
Article
PubMed
PubMed Central
Google Scholar
Falsini B, Piccardi M, Minnella A, Savastano C, Capoluongo E, Fadda A, Balestrazzi E, Maccarone R, Bisti S: Influence of saffron supplementation on retinal flicker sensitivity in early age-related macular degeneration. Invest Ophthalmol Vis Sci. 2010, 51 (12): 6118-6124. 10.1167/iovs.09-4995.
Article
PubMed
Google Scholar
Alpha-Tocopherol T, Group BCCPS: The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994, 330 (15): 1029-1035.
Article
Google Scholar
Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Cherniack MG, Brodkin CA, Hammar S: Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst. 1996, 88 (21): 1550-1559. 10.1093/jnci/88.21.1550.
Article
CAS
PubMed
Google Scholar