Effects of MAK on locomotor activity in the open-field test. Results are the mean ± S.E.M. The number of crossings recorded for a 30-min period. The number of rats per group was: control group, n = 6; MAK (0.3 g/kg)-treated group, n = 5; MAK (1 g/kg)-treated group, n = 5; imipramine-treated group, n = 5. *P < 0.05 compared with the control group, one-way analysis of variance followed by Tukey’s test.