Roberts JM, Wheeler AJ, Freiwald A: Reefs of the deep: the biology and geology of cold-water coral ecosystems. Science. 2006, 312: 543-547. 10.1126/science.1119861.
Article
CAS
PubMed
Google Scholar
Newman DJ, Cragg GM: Marine natural products and related compounds in clinical and advanced preclinical trials. J Nat Prod. 2004, 67: 1216-1238. 10.1021/np040031y.
Article
CAS
PubMed
Google Scholar
Brandt A, Gooday AJ, Brandao SN, Brix S, Brokeland W, Cedhagen T, Choudhury M, Cornelius N, Danis B, De Mesel I: First insights into the biodiversity and biogeography of the Southern Ocean deep sea. Nature. 2007, 447: 307-311. 10.1038/nature05827.
Article
CAS
PubMed
Google Scholar
Snelgrove PVR, Smith CR: A riot of species in an environmental calm: The paradox of the species-rich deep-sea floor. Oceanography and Marine Biology, Vol 40. Volume 40. Edited by: Gibson RN, Barnes M, Atkinson RJA. 2002, London: Taylor & Francis Ltd, 311-342. Oceanography and Marine Biology]
Google Scholar
Wright PC, Westacott RE, Burja AM: Piezotolerance as a metabolic engineering tool for the biosynthesis of natural products. Biomol Eng. 2003, 20: 325-331. 10.1016/S1389-0344(03)00042-X.
Article
CAS
PubMed
Google Scholar
Bull AT, Ward AC, Goodfellow M: Search and discovery strategies for biotechnology: the paradigm shift. Microbiol Mol Biol Rev. 2000, 64: 573-606. 10.1128/MMBR.64.3.573-606.2000.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kameyama T, Takahashi A, Kurasawa S, Ishizuka M, Okami Y, Takeuchi T, Umezawa H: Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. I. Taxonomy of the producing organism, isolation and biological properties. J Antibiot. 1987, 40: 1664-10.7164/antibiotics.40.1664.
Article
CAS
PubMed
Google Scholar
Homann VV, Sandy M, Tincu JA, Templeton AS, Tebo BM, Butler A: Loihichelins A− F, a Suite of Amphiphilic Siderophores Produced by the Marine Bacterium Halomonas LOB-5. J Nat Prod. 2009, 72: 884-888. 10.1021/np800640h.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li D, Wang F, Xiao X, Zeng X, Gu QQ, Zhu W: a new cytotoxic phenazine derivative from a deep sea bacterium Bacillus sp. Arch Pharm Res. 2007, 30: 552-555. 10.1007/BF02977647.
Article
PubMed
Google Scholar
Skropeta D: Deep-sea natural products. Nat Prod Rep. 2008, 25: 1131-1166. 10.1039/b808743a.
Article
CAS
PubMed
Google Scholar
Antunes A, Ngugi DK, Stingl U: Microbiology of the Red Sea (and other) deep‐sea anoxic brine lakes. Environ Microbiol Rep. 2011, 3: 416-433. 10.1111/j.1758-2229.2011.00264.x.
Article
PubMed
Google Scholar
Bonatti E: Punctiform initiation of seafloor spreading in the Red Sea during transition from a continental to an oceanic rift. Nature. 1985, 316: 33-37. 10.1038/316033a0.
Article
Google Scholar
Craig H: Isotopic composition and origin of the Red Sea and Salton Sea geothermal brines. Science. 1966, 154: 1544-1548. 10.1126/science.154.3756.1544.
Article
CAS
PubMed
Google Scholar
Hartmann M, Scholten J, Stoffers P, Wehner F: Hydrographic structure of brine-filled deeps in the Red Sea—new results from the Shaban, Kebrit, Atlantis II, and Discovery Deep. Mar Geol. 1998, 144: 311-330. 10.1016/S0025-3227(97)00055-8.
Article
CAS
Google Scholar
Anschutz P, Blanc G: The development of layering, fluxes through double-diffusive interfaces, and location of hydrothermal sources. J Geophys Res. 1998, 103: 27,809-827,819.
Article
Google Scholar
Schmidt M, Botz R, Faber E, Schmitt M, Poggenburg J, Garbe-Schönberg D, Stoffers P: High-resolution methane profiles across anoxic brine-seawater boundaries in the Atlantis-II, Discovery, and Kebrit deeps (Red Sea). Chem Geol. 2003, 200: 359-375. 10.1016/S0009-2541(03)00206-7.
Article
CAS
Google Scholar
Beech FW, Davenport RR: Isolation, purification, and maintenance of yeasts. Methods in microbiology. Vol. 4. Edited by: Booth C. 1971, London: Academic Press, 169-
Google Scholar
Dieffenbach CW, Dveksler GS: PCR primer: a laboratory manual. 2003, New York: Cold Spring Harbor Laboratory Pr
Google Scholar
Sorokin DY: Sulfitobacter pontiacus gen. nov., sp. nov. - a new heterotrophic bacterium from the Black Sea, specialized on sulfite oxidation. Microbiology. 1995, 64: 295-305.
Google Scholar
Kaye JZ, Baross JA: High incidence of halotolerant bacteria in Pacific hydrothermal-vent and pelagic environments. FEMS Microbiol Ecol. 2000, 32: 249-260. 10.1111/j.1574-6941.2000.tb00718.x.
Article
CAS
PubMed
Google Scholar
Kaye JZ, Marquez MC, Ventosa A, Baross JA: Halomonas neptunia sp. nov. Halomonas sulfidaeris sp. nov. Halomonas axialensis sp. nov. and Halomonas hydrothermalis sp. nov.: halophilic bacteria isolated from deep-sea hydrothermal-vent environments. Int J Syst Evol Micr. 2004, 54: 499-511. 10.1099/ijs.0.02799-0.
Article
CAS
Google Scholar
Brettar I, Christen R, Hofle MG: Idiomarina baltica sp. nov. a marine bacterium with a high optimum growth temperature isolated from surface water of the central Baltic Sea. Int J Syst Evol Micr. 2003, 53: 407-413. 10.1099/ijs.0.02399-0.
Article
CAS
Google Scholar
Romanenko LA, Schumann P, Rohde M, Zhukova NV, Mikhailov VV, Stackebrandt E: Marinobacter bryozoorum sp. nov. and Marinobacter sediminum sp. nov. novel bacteria from the marine environment. Int J Syst Evol Micr. 2005, 55: 143-148. 10.1099/ijs.0.63258-0.
Article
CAS
Google Scholar
Arahal DR, Ludwig W, Schleifer KH, Ventosa A: Phylogeny of the family Halomonadaceae based on 23S and 165 rDNA sequence analyses. Int J Syst Evol Micr. 2002, 52: 241-249.
Article
CAS
Google Scholar
Gomez-Gil B, Fajer-Avila E, Pascual J, Macian MC, Pujalte MJ, Garay E, Roque A: Vibrio sinaloensis sp. nov. isolated from the spotted rose snapper, Lutjanus guttatus Steindachner, 1869. Int J Syst Evol Micr. 2008, 58: 1621-1624. 10.1099/ijs.0.65719-0.
Article
CAS
Google Scholar
Cho BC, Hwang CY: Prokaryotic abundance and 16S rRNA gene sequences detected in marine aerosols on the East Sea (Korea). FEMS Microbiol Ecol. 2011, 76: 327-341. 10.1111/j.1574-6941.2011.01053.x.
Article
CAS
PubMed
Google Scholar
Tang J, Zheng A-p, Bromfield E, Zhu J, Li S-c, Wang S-q, Deng Q-m, Li P: 16S rRNA gene sequence analysis of halophilic and halotolerant bacteria isolated from a hypersaline pond in Sichuan, China. Ann Microbiol. 2011, 61: 375-381. 10.1007/s13213-010-0137-x.
Article
Google Scholar
Wang HZ, Chang CH, Lin CP, Tsai MC: Using MTT viability assay to test the cytotoxicity of antibiotics and steroid to cultured porcine corneal endothelial cells. J Ocul Pharmacol Ther. 1996, 12: 35-43. 10.1089/jop.1996.12.35.
Article
PubMed
Google Scholar
Bitzer J, Grosse T, Wang L, Lang S, Beil W, Zeeck A: New aminophenoxazinones from a marine Halomonas sp. fermentation, structure elucidation, and biological activity. J Antibiot (Tokyo). 2006, 59: 86-92. 10.1038/ja.2006.12.
Article
CAS
Google Scholar
Ruiz-Ruiz C, Srivastava GK, Carranza D, Mata JA, Llamas I, Santamaria M, Quesada E, Molina IJ: An exopolysaccharide produced by the novel halophilic bacterium Halomonas stenophila strain B100 selectively induces apoptosis in human T leukaemia cells. Appl Microbiol Biotechnol. 2011, 89: 345-355. 10.1007/s00253-010-2886-7.
Article
CAS
PubMed
Google Scholar
Wang L, Grosse T, Stevens H, Brinkhoff T, Simon M, Liang L, Bitzer J, Bach G, Zeeck A, Tokuda H, Lang S: Bioactive hydroxyphenylpyrrole-dicarboxylic acids from a new marine Halomonas sp. Production and structure elucidation. Appl Microbiol Biotechnol. 2006, 72: 816-822. 10.1007/s00253-006-0370-1.
Article
CAS
PubMed
Google Scholar
Schwartz LM, Osborne BA: Programmed cell death, apoptosis and killer genes. Immunol Today. 1993, 14: 582-590. 10.1016/0167-5699(93)90197-S.
Article
CAS
PubMed
Google Scholar
Lowe SW, Lin AW: Apoptosis in cancer. Carcinogenesis. 2000, 21: 485-495. 10.1093/carcin/21.3.485.
Article
CAS
PubMed
Google Scholar
Fadok VA, Laszlo DJ, Noble PW, Weinstein L, Riches DW, Henson PM: Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells. J Immunol. 1993, 151: 4274-4285.
CAS
PubMed
Google Scholar
Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM: Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol. 1992, 148: 2207-2216.
CAS
PubMed
Google Scholar
Martins RF, Ramos MF, Herfindal L, Sousa JA, Skaerven K, Vasconcelos VM: Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and Synechococcus. Mar Drugs. 2008, 6: 1-11. 10.3390/md6010001.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lin J, Yan XJ, Zheng L, Ma HH, Chen HM: Cytotoxicity and apoptosis induction of some selected marine bacteria metabolites. J Appl Microbiol. 2005, 99: 1373-1382. 10.1111/j.1365-2672.2005.02741.x.
Article
CAS
PubMed
Google Scholar
Schupp PJ, Kohlert-Schupp C, Whitefield S, Engemann A, Rohde S, Hemscheidt T, Pezzuto JM, Kondratyuk TP, Park EJ, Marler L: Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam. Nat Prod Commun. 2009, 4: 1717-1728.
CAS
PubMed
PubMed Central
Google Scholar
Thakur AN, Thakur NL, Indap MM, Pandit RA, Datar VV, Muller WE: Antiangiogenic, antimicrobial, and cytotoxic potential of sponge-associated bacteria. Mar Biotechnol (NY). 2005, 7: 245-252. 10.1007/s10126-004-4085-y.
Article
CAS
Google Scholar
Studzinski GP: Cell growth and apoptosis: a practical approach. 1995, Oxford: IRL Press at the Oxford University Press
Google Scholar
Härtel S, Zorn-Kruppa M, Tykhonova S, Alajuuma P, Engelke M, Diehl HA: Staurosporine‐induced apoptosis in human cornea epithelial cells in vitro. Cytometry A. 2003, 55: 15-23.
Article
PubMed
Google Scholar
Jessel R, Haertel S, Socaciu C, Tykhonova S, Diehl HA: Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells. J Cell Mol Med. 2002, 6: 82-92. 10.1111/j.1582-4934.2002.tb00313.x.
Article
CAS
PubMed
Google Scholar