Siegel R, DeSantis G, Virgo K, Stein K, Mariotto A, Smith T, Cooper D, Gansler T, Lerro C, Fedewa S, Lin C, Leach C, Cannady RS, Cho H, Scoppa S, Hachey M, Kirch R, Jemal A, Ward E: Cancer treatment and survivorship statistics. CA Cancer J Clin. 2012, 62: 220-241. 10.3322/caac.21149.
Article
PubMed
Google Scholar
Tannock IF, Ahles TA, Ganz PA, Van Dam FS: Cognitive impairment associated with chemotherapy for cancer: report of a workshop. J Clin Oncol. 2004, 22: 2233-2239. 10.1200/JCO.2004.08.094.
Article
PubMed
Google Scholar
Barnes PM, Bloom B, Nahin RL: Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Report. 2008, 12: 1-23.
PubMed
Google Scholar
Johannessen H, Hjelmborg J, Pasquarelli E, Fiorentini G, Di Costanzos F, Miccinesi G: Prevalence in the use of complementary medicine among cancer patients in Tuscany, Italy. Tumori. 2008, 94: 406-410.
PubMed
Google Scholar
Trager-Maury S, Tournigand C, Maindrault-Goebel F, Afchain P, De Gramont A, Garcia-Larnicol ML, Gervais H, Louvet C: Use of complementary medicine by cancer patients in a French oncology department. Bull Cancer. 2007, 94: 1017-1025.
PubMed
Google Scholar
Flinn JE: Bromium in acute lymphatic leukemia. J Am Inst Homeopath. 1965, 58: 213-214.
CAS
PubMed
Google Scholar
Preethi KC, Kuttan G, Kuttan R: Anti-tumour activity of rutagraveolens extract. Asian Pac J Cancer Prev. 2006, 7: 439-443.
CAS
PubMed
Google Scholar
Sur RK, Samajdar K, Mitra S, Gole MK, Chakrabarty BM: Hepatoprotective action of potentized lycopodium clavatum L. Br Homeopath J. 1990, 79: 152-156. 10.1016/S0007-0785(05)80334-5.
Article
Google Scholar
Frenkel M, Mishra BM, Sen S, Yang P, Pawlus A, Vence L, Leblanc A, Cohen L, Banerji P, Banerji P: Cytotoxic effects of ultra-diluted remedies on breast cancer cells. Int J Oncol. 2010, 36: 395-403.
PubMed
Google Scholar
MacLaughlin BW, Gutsmuths B, Pretner E, Jonas WB, Ives J, Kulawardane DV, Amri H: Effects of homeopathic preparations on human prostate cancer growth in cellular and animal models. Integr Cancer Ther. 2006, 5: 362-372.
Article
PubMed
Google Scholar
Guimarães FS, Andrade LF, Martins ST, Abud AP, Sene RV, Wanderer C, Tiscornia I, Bollati-Fogolín M, Buchi DF, Trindade ES: In vitro and in vivo anticancer properties of a Calcarea carbonica derivative complex (M8) treatment in a murine melanoma model. BMC Cancer. 2010, 10: 113-10.1186/1471-2407-10-113.
Article
PubMed
PubMed Central
Google Scholar
Sa G, Das T, Moon C, Hilston CM, Rayman PA, Rini BI, Tannenbaum CS, Finke JH: GD3, an overexpressed tumor-derived ganglioside, mediates the apoptosis of activated but not resting T cells. Cancer Res. 2009, 69: 3095-3104.
Article
CAS
PubMed
PubMed Central
Google Scholar
Das T, Sa G, Paszkiewicz-Kozik E, Hilston C, Molto L, Rayman P, Kudo D, Biswas K, Bukowski RM, Finke JH, Tannenbaum CS: Renal cell carcinoma tumors induce T cell apoptosis through receptor-dependent and receptor-independent pathways. J Immunol. 2008, 180: 4687-4696.
Article
CAS
PubMed
Google Scholar
Das T, Sa G, Hilston C, Kudo D, Rayman P, Biswas K, Molto L, Bukowski R, Rini B, Finke JH, Tannenbaum C: GM1 and tumor necrosis factor-alpha, overexpressed in renal cell carcinoma, synergize to induce T-cell apoptosis. Cancer Res. 2008, 68: 2014-2023. 10.1158/0008-5472.CAN-07-6037.
Article
CAS
PubMed
Google Scholar
Chattopadhyay S, Bhattacharyya S, Saha B, Chakraborty J, Mohanty S, Sakib Hossain DM, Banerjee S, Das K, Sa G, Das T: Tumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins. PLoS One. 2009, 4: e7382-10.1371/journal.pone.0007382.
Article
PubMed
PubMed Central
Google Scholar
Bhattacharyya S, Md Sakib Hossain D, Mohanty S, Sankar Sen G, Chattopadhyay S, Banerjee S, Chakraborty J, Das K, Sarkar D, Das T, Sa G: Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts. Cell Mol Immunol. 2010, 7: 306-315. 10.1038/cmi.2010.11.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bhattacharyya S, Mandal D, Saha B, Sen GS, Das T, Sa G: Curcumin prevents tumor-induced T cell apoptosis through stat-5a-mediated Bcl-2 induction. J Biol Chem. 2007, 282: 15954-15964. 10.1074/jbc.M608189200.
Article
CAS
PubMed
Google Scholar
Bhattacharyya S, Mandal D, Sen GS, Pal S, Banerjee S, Lahiry L, Finke JH, Tannenbaum CS, Das T, Sa G: Tumor-induced oxidative stress perturbs nuclear factor-kappaB activity-augmenting tumor necrosis factor-alpha-mediated T-cell death: protection by curcumin. Cancer Res. 2007, 67: 362-370. 10.1158/0008-5472.CAN-06-2583.
Article
CAS
PubMed
Google Scholar
Mandal D, Lahiry L, Bhattacharyya A, Bhattacharyya S, Sa G, Das T: Tumor-induced thymic involution via inhibition of IL-7R alpha and its JAK-STAT signaling pathway: protection by black tea. Int Immunopharmacol. 2006, 6: 433-444. 10.1016/j.intimp.2005.09.005.
Article
CAS
PubMed
Google Scholar
Mandal D, Bhattacharyya S, Lahiry L, Chattopadhyay S, Sa G, Das T: Black tea-induced decrease in IL-10 and TGF-beta of tumor cells promotes Th1/Tc1 response in tumor bearer. Nutr Cancer. 2007, 58: 213-221. 10.1080/01635580701328503.
Article
CAS
PubMed
Google Scholar
Das T, Sa G, Chattopadhyay S, Ray PK: Protein a-induced apoptosis of cancer cells is effected by soluble immune mediators. Cancer Immunol Immunother. 2002, 51: 376-380. 10.1007/s00262-002-0288-0.
Article
CAS
PubMed
Google Scholar
Guimaraes FSF, Abud AP, Oliveira SM, Oliveira CC, César B, Donatti L, Gabardo J, Trindade ES, Buchi DF: Stimulation of lymphocyte anti-melanoma activity by co-cultured macrophages activated by complex homeopathic medication. BMC Cancer. 2009, 9: 293-10.1186/1471-2407-9-293.
Article
PubMed
PubMed Central
Google Scholar
Klein G, Sjigren HO, Klein E, Hellstorm KE: Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host. Cancer Res. 1960, 20: 1561-1572.
CAS
PubMed
Google Scholar
Zhao Y, Bennett AD, Zheng Z, Wang QJ, Robbins PF, Yu LY, Li Y, Molloy PE, Dunn SM, Jakobsen BK, Rosenberg SA, Morgan RA: High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines. J Immunol. 2007, 179: 5845-5854.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pipkin ME, Lieberman J: Delivering the kiss of death: progress on understanding how perforin works. Curr Opin Immunol. 2007, 19: 301-308. 10.1016/j.coi.2007.04.011.
Article
CAS
PubMed
Google Scholar
Trapani JA, Smyth MJ: Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol. 2002, 2: 735-747. 10.1038/nri911.
Article
CAS
PubMed
Google Scholar
Russell JH, Ley TJ: Lymphocyte-mediated cytotoxicity. Annu Rev Immunol. 2002, 20: 323-370. 10.1146/annurev.immunol.20.100201.131730.
Article
CAS
PubMed
Google Scholar
Thiery J, Dorothee G, Haddada H, Echchakir H, Richon C, Stancou R, Vergnon I, Benard J, Mami-Chouaib F, Chouaib S: Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function. J Immunol. 2003, 170: 5919-5926.
Article
CAS
PubMed
Google Scholar
Dorothee G, Ameyar M, Bettaieb A, Vergnon I, Echchakir H, Bouziane M, Chouaib S, Mami-Chouaib F: Role of Fas and granule exocytosis pathways in tumor-infiltrating T lymphocyte-induced apoptosis of autologous human lung-carcinoma cells. Int J Cancer. 2001, 91: 772-777. 10.1002/1097-0215(200002)9999:9999<::AID-IJC1132>3.0.CO;2-V.
Article
CAS
PubMed
Google Scholar
Kawasaki Y, Saito T, Shirota-Someya Y, Ikegami Y, Komano H, Lee MH, Froelich CJ, Shinohara N, Takayama H: Cell death-associated translocation of plasma membrane components induced by CTL. J Immunol. 2000, 164: 4641-4648.
Article
CAS
PubMed
Google Scholar
Lahiry L, Saha B, Chakraborty J, Bhattacharyya S, Chattopadhyay S, Banerjee S, Choudhuri T, Mandal D, Bhattacharyya A, Sa G, Das T: Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis. Apoptosis. 2008, 13: 771-781. 10.1007/s10495-008-0213-x.
Article
CAS
PubMed
Google Scholar
Choudhuri T, Pal S, Das T, Sa G: Curcumin selectively induces apoptosis in deregulated cyclin D1 expressed cells at G2 phase of cell cycle in a p53-dependent manner. J Biol Chem. 2005, 280: 20059-20068. 10.1074/jbc.M410670200.
Article
CAS
PubMed
Google Scholar
Chakraborty J, Banerjee S, Ray P, Hossain DM, Bhattacharyya S, Adhikary A, Chattopadhyay S, Das T, Sa G: Gain of cellular adaptation due to prolong p53 impairment leads to functional switch-over from p53 to p73 during DNA damage in acute myeloid leukemia cells. J Biol Chem. 2010, 285: 33104-33112. 10.1074/jbc.M110.122705.
Article
CAS
PubMed
PubMed Central
Google Scholar
Adhikary A, Mohanty S, Lahiry L, Hossain DM, Chakraborty S, Das T: Theaflavins retard human breast cancer cell migration by inhibiting NF-kappaB via p53-ROS cross-talk. FEBS Lett. 2010, 584: 7-14. 10.1016/j.febslet.2009.10.081.
Article
CAS
PubMed
Google Scholar
Yamaguchi H, Wang HG: The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene. 2001, 20: 7779-7786. 10.1038/sj.onc.1204984.
Article
CAS
PubMed
Google Scholar
Staedler D, Idrizi E, Kenzaoui BH, Juillerat-Jeanneret L: Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells. Cancer Chemother Pharmacol. 2011, 68: 1161-1172. 10.1007/s00280-011-1596-x. [Epub ahead of print]
Article
CAS
PubMed
Google Scholar
Hou XW, Jiang Y, Wang LF, Xu HY, Lin HM, He XY, He JJ, Zhang S: Protective role of granulocyte colony-stimulating factor against adriamycin induced cardiac, renal and hepatic toxicities. Toxicol Lett. 2009, 187: 40-44. 10.1016/j.toxlet.2009.01.025.
Article
CAS
PubMed
Google Scholar
Hebishima T, Matsumoto Y, Watanabe G, Soma G, Kohchi C, Taya K, Hayashi Y, Hirota Y: Protective effects of the immunopotentiator from Pantoeaagglomerans 1 on chemotherapeutic agent-induced macrophage growth inhibition. Anticancer Res. 2010, 30: 2033-2040.
PubMed
Google Scholar
Seligmann IC, Lima PD, Cardoso PC, Khayat AS, Bahia MO, Buchi Dde F, Cabral IR, Burbano RR: The anticancer homeopathic composite "Canova method" is not genotoxic for human lymphocytes in vitro. Genet Mol Res. 2003, 30: 223-228.
Google Scholar
Hana G, Bar-Sela G, Zhana D, Mashiach T, Robinson E: The use of complementary and alternative therapies by cancer patients in northern Israel. Isr Med Assoc J. 2005, 7: 243-247.
PubMed
Google Scholar
Han SB, Lee CW, Kang MR, Yoon YD, Kang JS, Lee KH, Yoon WK, Lee K, Park SK, Kim HM: Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions. Cancer Lett. 2006, 243: 264-273. 10.1016/j.canlet.2005.11.040.
Article
CAS
PubMed
Google Scholar
Wälchli C, Baumgartner S, Bastide M: Effect of low doses and high homeopathic potencies in normal and cancerous human lymphocytes: an in vitro isopathic study. J Altern Complement Med. 2006, 12: 421-427. 10.1089/acm.2006.12.421.
Article
PubMed
Google Scholar
De Oliveira CC, Ana PR A, De Oliveira SM: Developments on drug discovery and on new therapeutics: highly diluted tinctures act as biological response modifiers. BMC Complement Altern Med. 2011, 11: 101-10.1186/1472-6882-11-101.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sato DY, Wal R, Oliveira CC, Cattaneo RI, Malvezzi M, Gabardo J, Buchi DF: Histopathological and immunophenotyping studies on normal and sarcoma 180-bearing mice treated with a Brazilian homeopathic medication. Homeopathy. 2005, 94: 26-32. 10.1016/j.homp.2004.10.003.
Article
CAS
PubMed
Google Scholar
Pascual-Carpe F, Vicente-Ortega V, Campos-Aranda M, Yañez-Gascón J: In vivo treatment of melanoma (B16F10) with a homeopathic agent and with a cytokine (IFN-α). Oncol Res. 2006, 16: 211-216.
CAS
PubMed
Google Scholar
Es S, Kuttan G, Kc P, Kuttan R: Effect of homeopathic medicines on transplanted tumors in mice. Asian Pac J Cancer Prev. 2007, 8: 390-394.
PubMed
Google Scholar
Xie Y, Bai O, Yuan J, Chibbar R, Slattery K, Wei Y, Deng Y, Xiang J: Tumor apoptotic bodies inhibit CTL responses and antitumor immunity via membrane-bound transforming growth factor-beta1 inducing CD8+ T-cell anergy and CD4+ Tr1 cell responses. Cancer Res. 2009, 69: 7756-7766. 10.1158/0008-5472.CAN-09-0496.
Article
CAS
PubMed
Google Scholar
Seligmann IC, Lima PD, Cardoso PC, Khayat AS, Bahia MO, Buchi De F, CabralI R, Burbano RR: The anticancer homeopathic composite "Canova method" is not genotoxic for human lymphocytes in vitro. Genet Mol Res. 2003, 2: 223-238.
PubMed
Google Scholar
Qu P, Yan C, Du H: Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis. Blood. 2011, 117: 4476-4489. 10.1182/blood-2010-07-298380. [Epub ahead of print]
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang H, Xie X, Lu WG, Ye DF, Chen HZ, Li X, Cheng Q: Ovarian carcinoma cells inhibit T cell proliferation: suppression of IL-2 receptor beta and gamma expression and their JAK-STAT signaling pathway. Life Sci. 2004, 74: 1739-1749. 10.1016/j.lfs.2003.07.051.
Article
CAS
PubMed
Google Scholar
Wang Y, Da’Dara AA, Thomas PG, Harn DA: Dendritic cells activated by an anti-inflammatory agent induce CD4+ T helper type 2 responses without impairing CD8+ memory and effector cytotoxic T-lymphocyte responses. Immunology. 2010, 129: 406-417. 10.1111/j.1365-2567.2009.03193.x.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pallis M, Grundy M, Turzanski J, Kofler R, Russell N: Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status. Blood. 2001, 98: 405-413. 10.1182/blood.V98.2.405.
Article
CAS
PubMed
Google Scholar
Fulda S, Debatin KM: Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene. 2006, 25: 4798-811. 10.1038/sj.onc.1209608.
Article
CAS
PubMed
Google Scholar