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  1. The aim of this study is investigate the antimicrobial effect of plant oils against bacterial strains isolated from neonatal asymptomatic bacteriuria (ABU) and to evaluate the antiseptic effect of the most pot...

    Authors: Rasha H. Bassyouni, Zeinat Kamel, Alkassem Ahmed Algameel, Ghada Ismail and Sylvana N. Gaber
    Citation: BMC Complementary Medicine and Therapies 2022 22:229
  2. Honey has broad spectrum antibacterial activity against clinically important organisms and may be suitable for treating superficial bacterial infections. However, very little data are available describing pote...

    Authors: Brayden H. Gray, Kathryn J. Green, Robbie R. Haines and Katherine A. Hammer
    Citation: BMC Complementary Medicine and Therapies 2022 22:228
  3. Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular ...

    Authors: Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani and Gaber El-Saber Batiha
    Citation: BMC Complementary Medicine and Therapies 2022 22:227
  4. Delay in episiotomy wound healing can lead to infection. The application of natural antimicrobial agents isolated from herbal essences can be a good strategy to prevent the growth of bacteria and promote the w...

    Authors: Fatemeh Hadizadeh-Talasaz, Fariba Mardani, Narjes Bahri, Hassan Rakhshandeh, Nasim Khajavian and Marzieh Taghieh
    Citation: BMC Complementary Medicine and Therapies 2022 22:226
  5. Complementary and alternative medicine (CAM) has played a critical role in ensuring universal access to basic health care services around the world. In Bangladesh, conventional medicine is a common approach fo...

    Authors: Md. Shahjalal, Jeff Gow, Md. Ashfikur Rahman, Md. Jakir Hossain, Md. Nafiul Alam Khan, Md. Sazzadul Alam, Ahmed Hossain and Rashidul Alam Mahumud
    Citation: BMC Complementary Medicine and Therapies 2022 22:225
  6. Oxidative stress can induce age-related diseases. Age-related retinal diseases, such as age-related macular degeneration (AMD), are difficult to cure owing to their complicated mechanisms. Although anti-neovas...

    Authors: Yibo Gong, Xuechun Wang, Yuchuan Wang, Peng Hao, Hao Wang, Yatu Guo and Wei Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:224
  7. Symphonia globulifera and Allophylus abyssinicus are used in the management of skin rashes and sores, cough, malaria, digestive diseases, stomach ache, wounds and helminthic infections among others in Uganda, Ken...

    Authors: Ben Lukubye, Clement Olusoji Ajayi, Rapheal Wangalwa and Grace Kagoro-Rugunda
    Citation: BMC Complementary Medicine and Therapies 2022 22:223
  8. Morinda citrifolia (Noni) is a plant that has long been used in various products such as foods and cosmetics. Although noni has been known to have immunostimulatory activity, detailed mechanism at the cellular le...

    Authors: Haeyeop Kim, Laily Rahmawati, Yo Han Hong, Su-Young Choi and Jae Youl Cho
    Citation: BMC Complementary Medicine and Therapies 2022 22:222
  9. The leaf of Eucalyptus globulus is commonly used in the traditional management of malaria. However, the efficacy of solvent fractions are didn’t study yet scientifically. Thus, this study aimed to investigate the...

    Authors: Mihret Ayalew, Seyfe Asrade Atnafie and Azmeraw Bekele
    Citation: BMC Complementary Medicine and Therapies 2022 22:221
  10. Zuojin formula, a traditional Chinese medicine, comprises Coptis chinensis and Evodia rutaecarpa. In our previous study, the total alkaloid extract from Zuojin formula (TAZF) showed potent and improved efficacy. ...

    Authors: Shuo Wang, Tao Zhang, Xiaoyan Liu, Zheng Yang, Ludi Li, Danping Shan, Yadong Gao, Yingzi Li, Yanying Li, Youbo Zhang and Qi Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:220
  11. Though there are reports about V. auriculifera antimicrobial activity, there is not enough information about its activity on some bacterial and fungal species. Besides, there was no quantitative evaluation done f...

    Authors: Teshale Etiso Wado, Sultan Suleman and Tesfaye Mohammed
    Citation: BMC Complementary Medicine and Therapies 2022 22:219
  12. Globally, the usage of herbal medicines (HMs) is increasingly growing in treating and preventing various ailments. Although, HMs play a vital role in healthcare, concerns have been raised over their safety. Si...

    Authors: Alemseghed Goitom, Feruz Yemane, Mussie Tsegay, Amanuel Kifleyesus, Senai Mihreteab Siele, Eyasu H. Tesfamariam and Nuru Abdu
    Citation: BMC Complementary Medicine and Therapies 2022 22:218
  13. Prasachandaeng (PSD) remedy has been empirically used in Thai traditional medicine to treat fever in bile duct and liver and cancer patients through Thai folk doctors. However, there have been no scientific re...

    Authors: Nuntika Prommee, Arunporn Itharat, Pakakrong Thongdeeying, Sunita Makchuchit, Weerachai Pipatrattanaseree, Adis Tasanarong, Buncha Ooraikul and Neal M. Davies
    Citation: BMC Complementary Medicine and Therapies 2022 22:217
  14. The traditional Chinese medicine (TCM) formula 01 for nasopharyngeal carcinoma (NPC01) is used in the management of head and neck cancers (HNCs), but whether NPC01 has an impact on the HR-QOL of patients with ...

    Authors: Li Yanwei, He Feng, Wang Xudong and Pan Zhanyu
    Citation: BMC Complementary Medicine and Therapies 2022 22:216
  15. Cordia myxa L. (Boraginaceae) is widely distributed in tropical regions and it’s fruits, leaves and stem bark have been utilized in folk medicine for treating trypanosomiasis caused by Trypanosoma cruzi. A popula...

    Authors: Gülsen Kendir, Ho Jung Bae, Jihyun Kim, Yongwoo Jeong, Hyo Jeoung Bae, Keontae Park, Xingquan Yang, Young-jin Cho, Ji-Young Kim, Seo Yun Jung, Ayşegül Köroğlu, Dae Sik Jang and Jong Hoon Ryu
    Citation: BMC Complementary Medicine and Therapies 2022 22:215
  16. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes local bone erosion and systemic osteoporosis. Harpagoside (HAR), an iridoid glycoside, has various pharmacological effects on ...

    Authors: Ju-Young Kim, Yoon-Hee Cheon, Sung-Jun Ahn, Sung Chul Kwak, Chong Hyuk Chung, Chang Hoon Lee and Myeung Su Lee
    Citation: BMC Complementary Medicine and Therapies 2022 22:214
  17. Salvia-Nelumbinis naturalis (SNN), the extract of Chinese herbal medicine, has shown effects on NAFLD. This study aims to explore the underlying mechanism of SNN for regulating the lipid metabolism disorder in...

    Authors: Yang Liu, Yiping Li, Jue Wang, Lili Yang, Xiao Yu, Ping Huang, Haiyan Song and Peiyong Zheng
    Citation: BMC Complementary Medicine and Therapies 2022 22:213
  18. Complementary Medicine (CM) is widely used internationally but there is limited understanding of the forms of knowledge CM practitioners use in their clinical practice and how they use this knowledge in intera...

    Authors: Kate Davies, Milena Heinsch, Campbell Tickner, Caragh Brosnan, Amie Steel, Gupteswar Patel and Molly Marsh
    Citation: BMC Complementary Medicine and Therapies 2022 22:212
  19. Intestinal inflammation is considered to be an important characteristic of ulcerative colitis (UC) and the current medical treatments for UC are usually proposed to suppress abnormal intestinal immune response...

    Authors: Ming-Kuem Lin, Ya-Ting Yang, Li-Jen Lin, Wei-Hsuan Yu and Huan-Yuan Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:211
  20. Diabetic nephropathy (DN) is one of the most serious complications of diabetes and the main cause of end-stage renal failure. Rhubarb is a widely used traditional Chinese herb, and it has exhibited efficacy in...

    Authors: Shaojie Fu, Yena Zhou, Cong Hu, Zhonggao Xu and Jie Hou
    Citation: BMC Complementary Medicine and Therapies 2022 22:210
  21. The Sheng-ji Hua-yu (SJHY) formula is a quite effective Traditional Chinese Medicines (TCM) in the treatment of delayed diabetic wounds. Previous research has shown that the SJHY formula has significant anti-i...

    Authors: Ning Xu, Yuanran Chen, Dongjie Guo, Yu Deng, Wanjun Guo, Xin Liu, Yi Wang, Hanzhi Lu, Aijun Liu, Jianyong Zhu and Fulun Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:209
  22. Acute pancreatitis is a common and potentially serious condition. However, a specific treatment for this condition is still lacking. Genistein, with its anti-oxidant and anti-inflammatory effects, could possib...

    Authors: Prasong Siriviriyakul, Jumlongluk Sriko, Kanjana Somanawat, Maneerat Chayanupatkul, Naruemon Klaikeaw and Duangporn Werawatganon
    Citation: BMC Complementary Medicine and Therapies 2022 22:208
  23. The number of COVID-19 cases continues to grow in Indonesia. This phenomenon motivates researchers to find alternative drugs that function for prevention or treatment. Due to the rich biodiversity of Indonesia...

    Authors: Linda Erlina, Rafika Indah Paramita, Wisnu Ananta Kusuma, Fadilah Fadilah, Aryo Tedjo, Irandi Putra Pratomo, Nabila Sekar Ramadhanti, Ahmad Kamal Nasution, Fadhlal Khaliq Surado, Aries Fitriawan, Khaerunissa Anbar Istiadi and Arry Yanuar
    Citation: BMC Complementary Medicine and Therapies 2022 22:207
  24. Ginkgo biloba extracts (GBE) have been used in traditional medicines for centuries. GBE has been shown to deliver protective effects against symptoms of age-related cognitive decline. Despite there being standard...

    Authors: David Briskey and Amanda Rao
    Citation: BMC Complementary Medicine and Therapies 2022 22:206
  25. In recent decades, it has been possible to observe an increase in Complementary and Alternative Medicine (CAM) usage globally for both disease prevention and health promotion purposes. we aim to estimate the p...

    Authors: Patricia de Moraes Mello Boccolini, Karine de Lima Sírio Boclin, Islândia Maria Carvalho de Sousa and Cristiano Siqueira Boccolini
    Citation: BMC Complementary Medicine and Therapies 2022 22:205
  26. Existing evidence marked a prevalent use of Complementary and Alternative Medicine (CAM) therapies in Lebanon that is concomitant with low rates of disclosure to health care providers and limited knowledge amo...

    Authors: Zeinab Jaafar, Jennifer Ayoub, Rena Hamadeh, Samar Baydoun, Gladys Honein-AbouHaidar, Jinan Banna, Mohamad Alameddine and Farah Naja
    Citation: BMC Complementary Medicine and Therapies 2022 22:204
  27. Henna (Lawsonia inermis) with anti-bacterial properties has been widely used in traditional medicine especially Persian medicine. Henna oil is suggested for diseases of infectious origin, such as cervical ulcers....

    Authors: M. Fatahi Bafghi, S. Salary, F. Mirzaei, H. Mahmoodian, H. Meftahizade and R. Zareshahi
    Citation: BMC Complementary Medicine and Therapies 2022 22:203
  28. Research exploring the use of specific Complementary and Alternative Medicine (CAM) modalities by Norwegian cancer patients is sparse. The aims of this study were therefor to map the different CAM modalities c...

    Authors: Agnete E. Kristoffersen, Jorunn V. Nilsen, Trine Stub, Johanna Hök Nordberg, Barbara Wider, Dana Mora, Kiwumulo Nakandi and Mona Bjelland
    Citation: BMC Complementary Medicine and Therapies 2022 22:202
  29. The aim of this study was to evaluate the biological effects of hydroalcoholic extract of Psidium guajava L leaves and phenytoin as a standard agent on the induced oral mucosal wound.

    Authors: Faezeh Ghaderi, Elham Ebrahimi, Fatemeh Sari Aslani, Omid Koohi-Hosseinabadi, Farhad Koohpeyma, Cambyz Irajie, Nader Tanideh and Aida Iraji
    Citation: BMC Complementary Medicine and Therapies 2022 22:201
  30. Determining which therapies fall under the umbrella of complementary, alternative, and/or integrative medicine (CAIM) is difficult for several reasons. An operational definition is dynamic, and changes dependi...

    Authors: Jeremy Y. Ng, Tushar Dhawan, Ekaterina Dogadova, Zhala Taghi-Zada, Alexandra Vacca, Renee-Gabrielle Fajardo, Hooriya A. Masood, Riva Patel, Samira Sunderji, L. Susan Wieland and David Moher
    Citation: BMC Complementary Medicine and Therapies 2022 22:200
  31. The incidence of allergic reaction is increasing year by year, but the specific mechanism is still unclear. Paeonia lactiflora Pall.(PLP) is a traditional Chinese medicine with various pharmacological effects suc...

    Authors: Yang Zhao, Hui Li, Xiangsheng Li, Yizhao Sun, Yuxin Shao, Yanfen Zhang and Zhongcheng Liu
    Citation: BMC Complementary Medicine and Therapies 2022 22:199
  32. Berberine (BBR) has been found to have antiobesity effects, and obesity can lead to adipose tissue degeneration. As a special adipose tissue, perivascular adipose tissue (PVAT) is closely related to vascular f...

    Authors: Man Wang, Xufang Geng, Kaipeng Li, Yawen Wang, Xiaofeng Duan, Congcong Hou, Lili Zhao, Huimin Zhou and Ding Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:198
  33. Plantainoside D is widely existed in the herbs and possesses various pharmacological activities, making it possible to co-administrate with other herbs. Its effect on cytochrome P450 enzymes (P450) is a risk f...

    Authors: Jin Zhou, Xian Qian, Yanqing Zhou, Shili Xiong, Shuxia Ji, Ying Wang and Ping Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:197
  34. Ulcerative colitis (UC) is an inflammatory bowel disease. Fucoidan, sulfated polysaccharide of brown seaweed, demonstrates various pharmacological actions as anti-inflammatory, anti-tumor and anti-bacterial ef...

    Authors: Alaa Bagalagel, Reem Diri, Ahmad Noor, Deina Almasri, Hussain T. Bakhsh, Hussam I. Kutbi and Mohammed M. H. Al-Gayyar
    Citation: BMC Complementary Medicine and Therapies 2022 22:196
  35. The rise of multidrug-resistant (MDR) bacteria is a real public health problem worldwide and is responsible for the increase in hospital infections. Donella welwitschii is a liana or shrub belonging to the family...

    Authors: Michel-Gael F. Guefack, Marcelle O. Ngangoue, Armelle T. Mbaveng, Paul Nayim, Jenifer R. N. Kuete, Carine M. N. Ngaffo, Godloves F. Chi, Bathelemy Ngameni, Bonaventure T. Ngadjui and Victor Kuete
    Citation: BMC Complementary Medicine and Therapies 2022 22:194
  36. Staphylococcus aureus has prevailed against the majority of antibiotics currently in clinical use, making it a significant global public health problem. As a safer alternative, bioactive compounds have been explo...

    Authors: Uwem Okon Edet, Francisca Obiageri Nwaokorie, Elizabeth Nkagafel Mbim, Edet Effiong Asanga, Yeneochia Ogar Agbor, Henshaw Uchechi Okoroiwu, Bassey Okon Edet, Nikita Umoafia and Ani Nkang
    Citation: BMC Complementary Medicine and Therapies 2022 22:192
  37. The ongoing novel coronavirus disease 2019 (COVID-19) pandemic has a significant mortality rate of 3–5%. The principal causes of multiorgan failure and death are cytokine release syndrome and immune dysfunctio...

    Authors: Indranill Basu-Ray, Kashinath Metri, Dibbendhu Khanra, Rishab Revankar, Kavitha M. Chinnaiyan, Nagaratna Raghuram, Mahesh Chandra Mishra, Bhushan Patwardhan, Manjunath Sharma, Ishwar V. Basavaraddi, Akshay Anand, Shrinath Reddy, K. K. Deepak, Marian Levy, Sue Theus, Glenn N. Levine…
    Citation: BMC Complementary Medicine and Therapies 2022 22:191
  38. Atherosclerosis (AS) is the greatest contributor to pathogenesis of atherosclerotic cardiovascular disease (ASCVD), which is associated with increased mortality and reduced quality of life. Early intervention ...

    Authors: Zheng Jin, Huanyi Zhao, Yuan Luo, Xiushen Li, Jiayan Cui, Jing Yan and Pingzhen Yang
    Citation: BMC Complementary Medicine and Therapies 2022 22:190
  39. hyperlipidemia acute pancreatitis (HTG-AP) is a major hidden danger affecting human health, however, whether there is a protective effect of resveratrol on HTG-AP is unclear. Therefore our study was aimed to i...

    Authors: Xiaoying Zhang, Guodong Yang, Yulin Chen, Zhao Mu, Haiyue Zhou and Luoyao Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:189
  40. Ginsenoside Rg3 (GRg3) is one of the main active ingredients in Chinese ginseng extract and has various biological effects, such as immune-enhancing, antitumour, antiangiogenic, immunomodulatory and anti-infla...

    Authors: Shangbin Lv, Xiaodong Chen, Yu Chen, Daoyin Gong, Gang Mao, Caifei Shen, Ting Xia, Jing Cheng, Zhaoliang Luo, Yu Cheng, Weihong Li and Jinhao Zeng
    Citation: BMC Complementary Medicine and Therapies 2022 22:188
  41. Rheumatoid arthritis (RA) is a chronic, progressive, systemic autoimmune inflammatory disease. Bi Zhong Xiao decoction (BZXD) performs multiple functions for rheumatoid arthritis (RA) treatment for decades. In...

    Authors: Cailin He, Yang Wang, Yuqi Wen, Teng Li, En Hu, Siqing Zeng and Xingui Xiong
    Citation: BMC Complementary Medicine and Therapies 2022 22:186
  42. As an original traditional Chinese medicinal formula, Qin Huang formula (QHF) is used as adjuvant therapy for treating lymphoma in our hospital and has proven efficacy when combined with chemotherapy. However,...

    Authors: Weili Li, Lingling Lv, Ming Ruan, Jiayue Xu, Wenhua Zhu, Qiong Li, Xufeng Jiang, Lan Zheng and Weirong Zhu
    Citation: BMC Complementary Medicine and Therapies 2022 22:185
  43. H. brasiletto is used in popular culture due to its therapeutic properties, including antioxidant, anti-inflammatory and antiproliferative properties, although little is known about its role as a protector agains...

    Authors: Margareth Duran-Izquierdo, María Taboada-Alquerque, Lucellys Sierra-Marquez, Neda Alvarez-Ortega, Elena Stashenko and Jesus Olivero-Verbel
    Citation: BMC Complementary Medicine and Therapies 2022 22:184
  44. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12906-020-2834-8.

    Authors: Li-Min Zhang, Rong-Rong Zhen, Chao Gu, Tian-Li Zhang, Yue Li, Miao Jin, Bing Hu and Hong-Mei An
    Citation: BMC Complementary Medicine and Therapies 2022 22:183
  45. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ignacio Peralta, Carla Marrassini, Malen Saint Martin, Laura Cogoi, Maria Rosario Alonso, Alejandro Gugliucci and Claudia Anesini
    Citation: BMC Complementary Medicine and Therapies 2022 22:182

    The original article was published in BMC Complementary Medicine and Therapies 2022 22:84

  46. Anthocyanin-containing plant extracts and carotenoids, such as astaxanthin, have been well-known for their antiviral and anti-inflammatory activity, respectively. We hypothesised that a mixture of Ribes nigrum L.

    Authors: Rinu Sivarajan, Heike Oberwinkler, Valeria Roll, Eva-Maria König, Maria Steinke and Jochen Bodem
    Citation: BMC Complementary Medicine and Therapies 2022 22:181
  47. Atherosclerosis (AS) is the primary cause of cardiovascular disease and the incidence is extremely common; however, there are currently few drugs that can effectively treat AS. Although oridonin has been widel...

    Authors: Zhipeng Chen, Heqian Liu, Xiaoqi Zhao, Subinur Mamateli, Cheng Liu, Lei Wang, Jing Yu, Yutong Liu, Jing Cai and Tong Qiao
    Citation: BMC Complementary Medicine and Therapies 2022 22:180