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  1. This study was designed to evaluate the effects of electroacupuncture-like stimulation at Baihui (GV20) and Dazhui (GV14) acupoints (EA at acupoints) following mild cerebral ischemia-reperfusion (I/R) injury. ...

    Authors: Chin Yi Cheng, Jaung Geng Lin, Shan Yu Su, Nou Ying Tang, Shung Te Kao and Ching Liang Hsieh
    Citation: BMC Complementary and Alternative Medicine 2014 14:92
    Content type: Research article Published on:

  2. Berberine is an isoquinoline alkaloid mainly extracted from Rhizoma Coptidis and has been shown to possess a potent inhibitory activity against bacterial. However, the role of berberine in anti-bacterial action h...

    Authors: Ming Chu, Ran Ding, Zheng-yun Chu, Ming-bo Zhang, Xiao-yan Liu, Shao-hua Xie, Yan-jun Zhai and Yue-dan Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:89
    Content type: Research article Published on:

  3. Alzheimer’s disease (AD) is the most common type of presenile and senile dementia. The human β-amyloid precursor cleavage enzyme (BACE-1) is a key enzyme responsible for amyloid plaque production, which implic...

    Authors: Xue Wang, Jun-Ran Kim, Seong-Baek Lee, Young-Joon Kim, Moon Young Jung, Hyung-Wook Kwon and Young-Joon Ahn
    Citation: BMC Complementary and Alternative Medicine 2014 14:88
    Content type: Research article Published on:

  4. Artemisia nilagirica (Asteraceae) and Murraya koenigii (Rutaceae) are widely distributed in eastern region of India. Leaves of Artemisia nilagirica plant are used to treat cold and cough by the local tribal popu...

    Authors: Sumanta Kumar Naik, Soumitra Mohanty, Avinash Padhi, Rashmirekha Pati and Avinash Sonawane
    Citation: BMC Complementary and Alternative Medicine 2014 14:87
    Content type: Research article Published on:

  5. Radix Trichosanthis (RT), the dry root tuber of Trichosanthis kirilowii Maxim (Cucurbitaceae), is a traditional Chinese medicine. Although a wide range of saponin pharmacological properties has been identified, t...

    Authors: Ying Chen, Yonghong Miao, Liyong Huang, Juxiang Li, Haiyan Sun, Yuanzeng Zhao, Jing Yang and Wenke Zhou
    Citation: BMC Complementary and Alternative Medicine 2014 14:86
    Content type: Research article Published on:

  6. The National Institutes of Health reported in 2007 that approximately 38% of United States adults have used at least one type of Complementary and Alternative Medicine (CAM). There are no studies available tha...

    Authors: Lisa Strouss, Amy Mackley, Ursula Guillen, David A Paul and Robert Locke
    Citation: BMC Complementary and Alternative Medicine 2014 14:85
    Content type: Research article Published on:

  7. In tuberculosis (TB), the steadily increasing bacterial resistance to existing drugs and latent TB continue to be major concerns. A combination of conventional drugs and plant derived therapeutics can serve to...

    Authors: Pooja Gupta, Purva Bhatter, Desiree D’souza, Monica Tolani, Poonam Daswani, Pundarikakshudu Tetali and Tannaz Birdi
    Citation: BMC Complementary and Alternative Medicine 2014 14:84
    Content type: Research article Published on:

  8. Cyperus rotundus Linn. (Cyperaceae) is used to treat inflammation, pain, fever, wounds, boils and blisters in folk medicine. This study evaluated the antinociceptive effect of the hydromethanol extract of whole ...

    Authors: Mohammad Zafar Imam and Chandra Datta Sumi
    Citation: BMC Complementary and Alternative Medicine 2014 14:83
    Content type: Research article Published on:

  9. An embryonic toxicity of Rhizoma sparganii was observed in mice. This study was aimed to evaluate the anticancer effects of ...

    Authors: Jun-Wu Zhang and Ya-Hui Wei
    Citation: BMC Complementary and Alternative Medicine 2014 14:82
    Content type: Research article Published on:

    The Retraction Note to this article has been published in BMC Complementary and Alternative Medicine 2017 17:260

  10. Hydrogen has been reported to relieve damage in many disease models, and is a potential additive in drinking water to provide protective effects for patients as several clinical studies revealed. However, the ...

    Authors: Jinling Xue, Guodong Shang, Yoshinori Tanaka, Yasuhiro Saihara, Lingyan Hou, Natalia Velasquez, Wenjun Liu and Yun Lu
    Citation: BMC Complementary and Alternative Medicine 2014 14:81
    Content type: Research article Published on:

  11. Dai Huang Fu Zi Tang (DHFZT), an oriental herbal formula, has long been used clinically in treatment of intestinal obstruction, acute pancreatitis, cholecystalgia and chronic diarrhea for thousands of years. R...

    Authors: Xiaoguang Lu, Xin Kang, Libin Zhan, Chunyu Lv, Zhiwei Fan, Yingli Wang, Robbie Ali, Chang Lv, Siyao Li and Jinhai Mu
    Citation: BMC Complementary and Alternative Medicine 2014 14:80
    Content type: Research article Published on:

  12. The issue of resistance in malarial infection makes development of novel drugs a necessity. An alternative source for discovering such drugs is natural products. Croton macrostachyus H. (Euphorbiaceae) is used in...

    Authors: Laychiluh Bantie, Solomon Assefa, Tilahun Teklehaimanot and Ephrem Engidawork
    Citation: BMC Complementary and Alternative Medicine 2014 14:79
    Content type: Research article Published on:

  13. Soshiho-tang (SST) is a traditional medicine widely used for the treatment of chronic hepatitis. SST has been shown to confer a variety of pharmacological activities, including prevention of hepatotoxicity, pr...

    Authors: Jung-Jin Lee, Hyeeun Kwon, Ji-Hye Lee, Dong-Gun Kim, Sang-Hyuk Jung and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2014 14:78
    Content type: Research article Published on:

  14. Cancer and HIV/AIDS are two of the greatest public health and humanitarian challenges facing the world today. Infection with HIV not only weakens the immune system leading to AIDS and increasing the risk of op...

    Authors: Mona S Ellithey, Namrita Lall, Ahmed A Hussein and Debra Meyer
    Citation: BMC Complementary and Alternative Medicine 2014 14:77
    Content type: Research article Published on:

  15. The primary objective of the present investigation is to evaluate the antidiabetic, antihyperlidemic and antioxidant activity of the methanolic extract of the Paederia foetida Linn. (PF) leaf extract in the strep...

    Authors: Vikas Kumar, Firoz Anwar, Danish Ahmed, Amita Verma, Aftab Ahmed, Zoheir A Damanhouri, Vatsala Mishra, Pramod W Ramteke, Prakash Chandra Bhatt and Mohd Mujeeb
    Citation: BMC Complementary and Alternative Medicine 2014 14:76
    Content type: Research article Published on:

  16. In previous works we have shown that a low-molecular-mass (LMM) fraction from mushroom (Lentinus edodes) homogenate interferes with binding of Streptococcus mutans to hydroxyapatite and Prevotella intermedia to g...

    Authors: Caterina Signoretto, Anna Marchi, Anna Bertoncelli, Gloria Burlacchini, Adele Papetti, Carla Pruzzo, Egija Zaura, Peter Lingström, Itzhak Ofek, Jonathan Pratten, David A Spratt, Michael Wilson and Pietro Canepari
    Citation: BMC Complementary and Alternative Medicine 2014 14:75
    Content type: Research article Published on:

  17. It has been suggested that the formation of osteoblasts in bone marrow is closely associated with adipogenesis, and the balance between osteogenesis and adipogenesis differentiation of MSCs (mesenchymal stem c...

    Authors: Feng Yang, Pu-wei Yuan, Yang-Quan Hao and Zheng-Mao Lu
    Citation: BMC Complementary and Alternative Medicine 2014 14:74
    Content type: Research article Published on:

  18. The cosmetic and pharmaceutical industries have an increasing interest in replacing synthetic antimicrobials in dermatological products due to increased microbial resistance to conventional antimicrobial agent...

    Authors: Lilian FB Amaral, Patricia Moriel, Mary Ann Foglio and Priscila G Mazzola
    Citation: BMC Complementary and Alternative Medicine 2014 14:73
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2014 14:154

  19. Nuclear factor-erythroid 2 p45 related factor 2 (Nrf2) is a primary transcription factor, protecting cells from oxidative stress by regulating a number of antioxidants and phase II detoxifying enzymes. Dietary...

    Authors: Wan Nuraini Wan Hasan, Mi-Kyoung Kwak, Suzana Makpol, Wan Zurinah Wan Ngah and Yasmin Anum Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2014 14:72
    Content type: Research article Published on:

  20. Isodon rugosus is used in folk Pakistan traditional practices to cure ailments related to gastrointestinal, respiratory and cardiovascular problems. Present study was undertaken to validate these folkloric uses.

    Authors: Khalid Hussain Janbaz, Javeria Arif, Fatima Saqib, Imran Imran, Muhammad Ashraf, Muhammad Zia-Ul-Haq, Hawa ZE Jaafar and Vincenzo De Feo
    Citation: BMC Complementary and Alternative Medicine 2014 14:71
    Content type: Research article Published on:

  21. Gymnema sylvestre is a highly valued ethno pharmacologically important medicinal plant used currently in many poly-herbal formulations due to its potential antidiabetic activity and other health benefits. The pr...

    Authors: Lilly Baptista Arun, Aarrthy M Arunachalam, Kantha Deivi Arunachalam, Sathesh Kumar Annamalai and Kalaivani Amit Kumar
    Citation: BMC Complementary and Alternative Medicine 2014 14:70
    Content type: Research article Published on:

  22. Deqi is a central concept in traditional Chinese acupuncture. We performed a secondary analysis on data from a larger randomized controlled trial (RCT) in order to assess the effect of acupuncture on deqi traits...

    Authors: Guang-Xia Shi, Qian-Qian Li, Cun-Zhi Liu, Jiang Zhu, Lin-Peng Wang, Jing Wang, Li-Li Han, Li-Ping Guan and Meng-Meng Wu
    Citation: BMC Complementary and Alternative Medicine 2014 14:69
    Content type: Research article Published on:

  23. Zyflamend, a mixture containing extracts of ten herbs, has shown promise in a variety of preclinical cancer models, including prostate cancer. The current experiments were designed to investigate the effects o...

    Authors: E-Chu Huang, Yi Zhao, Guoxun Chen, Seung Joon Baek, Michael F McEntee, Steven Minkin, John P Biggerstaff and Jay Whelan
    Citation: BMC Complementary and Alternative Medicine 2014 14:68
    Content type: Research article Published on:

  24. Chinese herbal formulae are composed of complex components and produce comprehensive pharmacological effects. Unlike chemical drugs that have only one clear single target, the components of Chinese herbal form...

    Authors: Yong Wang, Chun Li, Zhongyang Liu, Tianjiao Shi, Qiyan Wang, Dong Li, Yan Wu, Jing Han, Shuzhen Guo, Binghua Tang and Wei Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:67
    Content type: Research article Published on:

  25. Although various studies have been conducted to shed light on the pharmacological actions of khat, little or no data are available regarding khat’s effect on the renal redox system. The aim of this study was t...

    Authors: Zewdneh Shewamene and Ephrem Engidawork
    Citation: BMC Complementary and Alternative Medicine 2014 14:66
    Content type: Research article Published on:

  26. Commelina benghalensis (CB) is a small plant whose fleshy stems are used in South Africa to treat skin conditions (e.g., cancerous skin outgrowths). This study was aimed at evaluating the effect of sub-fractions...

    Authors: Kgomotso Welheminah Lebogo, Matlou Phineas Mokgotho, Victor Patrick Bagla, Thabe Moses Matsebatlela, Vusi Mbazima, Leshwene Jeremiah Shai and Leseilane Mampuru
    Citation: BMC Complementary and Alternative Medicine 2014 14:65
    Content type: Research article Published on:

  27. Protein tyrosine phosphatase (PTP) 1B, a negative regulator of the insulin and leptin signaling pathways, is currently considered a promising target for the development of novel therapeutic approaches used to ...

    Authors: Toshihisa Onoda, Wei Li, Koji Higai and Kazuo Koike
    Citation: BMC Complementary and Alternative Medicine 2014 14:64
    Content type: Research article Published on:

  28. Muntingia calabura (Elaecoparceae) is a medicinal plant traditionally used, particularly, by the Peruvian people to alleviate headache and cold, pain associated with gastric ulcers or to reduce the prostate glan...

    Authors: Zainul Amiruddin Zakaria, Mohd Hijaz Mohd Sani, Manraj Singh Cheema, Arifah Abdul Kader, Teh Lay Kek and Mohd Zaki Salleh
    Citation: BMC Complementary and Alternative Medicine 2014 14:63
    Content type: Research article Published on:

  29. Invasion of fibroblast-like synoviocytes (FLSs) is critical in the pathogenesis of rheumatoid arthritis (RA). The metalloproteinases (MMPs) and activator of nuclear factor-kappa B (NF-κB) pathway play a critic...

    Authors: Guoqing Li, Dan Liu, Shiyu Guo, Masataka Sunagawa, Tadashi Hisamitsu and Yanqing Liu
    Citation: BMC Complementary and Alternative Medicine 2014 14:62
    Content type: Research article Published on:

  30. Erythrina verna, popularly known as “mulungu”, is a Brazilian medicinal plant used to treat anxiety. Erythrina alkaloids have been described in several species of Erythrina, which have biological and therapeutic...

    Authors: Thais Guaratini, Denise Brentan Silva, Aline Cavalli Bizaro, Lucas Rossi Sartori, Hans-Ulrich Humpf, Norberto Peporine Lopes, Letícia Veras Costa-Lotufo and João Luis Callegari Lopes
    Citation: BMC Complementary and Alternative Medicine 2014 14:61
    Content type: Research article Published on:

  31. Azoxymethane (AOM) is a potent carcinogenic agent commonly used to induce colon cancer in rats; the cytotoxicity of AOM is considered to mediate oxidative stress. This study investigated the chemopreventive ef...

    Authors: Mostafa I Waly, Amani S Al-Rawahi, Marwa Al Riyami, Mohamed A Al-Kindi, Halima K Al-Issaei, Sardar A Farooq, Ahmed Al-Alawi and Mohammad S Rahman
    Citation: BMC Complementary and Alternative Medicine 2014 14:60
    Content type: Research article Published on:

  32. Most users of complementary and alternative medicine (CAM) combine it with conventional medicine. Recent risk assessment studies have shown risks of negative interactions between CAM and conventional medicine,...

    Authors: Lasse Skovgaard, Inge Kryger Pedersen and Marja Verhoef
    Citation: BMC Complementary and Alternative Medicine 2014 14:59
    Content type: Research article Published on:

  33. Spices and herbs have been used in food since ancient times to give taste and flavor and also as food preservatives and disease remedies. In Cameroon, the use of spices and other aromatic plants as food flavor...

    Authors: Jean Paul Dzoyem, Roland T Tchuenguem, Jules R Kuiate, Gerald N Teke, Frederick A Kechia and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2014 14:58
    Content type: Research article Published on:

  34. Moringa oleifera is a plant found in many tropical and subtropical countries. Many different uses and properties have been attributed to this plant, mainly as a nutritional supplement and as a water purifier. It...

    Authors: Belen Torondel, David Opare, Bjorn Brandberg, Emma Cobb and Sandy Cairncross
    Citation: BMC Complementary and Alternative Medicine 2014 14:57
    Content type: Research article Published on:

  35. Provision of clinically relevant information about complementary and alternative medicine (CAM) to health care professionals is not well described. The aim of the study was to assess questions about CAM to the...

    Authors: Jan Schjøtt and Hilde Erdal
    Citation: BMC Complementary and Alternative Medicine 2014 14:56
    Content type: Research article Published on:

  36. Breast cancer is one of the most dreading types of cancer among women. Herbal medicine has becoming a potential source of treatment for breast cancer. Herbal plant Dillenia suffruticosa (Griff) Martelli under the...

    Authors: Yin Sim Tor, Latifah Saiful Yazan, Jhi Biau Foo, Nurdin Armania, Yoke Kqueen Cheah, Rasedee Abdullah, Mustapha Umar Imam, Norsharina Ismail and Maznah Ismail
    Citation: BMC Complementary and Alternative Medicine 2014 14:55
    Content type: Research article Published on:

  37. Biyeom-Tang, a medicine prescribed by oriental clinics, has been used for the treatment of the allergic rhinitis (AR). In the present study, an ethanol extract of Biyeom-Tang (EBT) was investigated for anti-al...

    Authors: Kyu-Tae Jeong, Sun-Gun Kim, Jiean Lee, Young Na Park, Hyo-Hyun Park, Na-Young Park, Keuk-Jun Kim, Hwadong Lee, Youn Ju Lee and Eunkyung Lee
    Citation: BMC Complementary and Alternative Medicine 2014 14:54
    Content type: Research article Published on:

  39. Endophytes, which reside in plant tissues, have the potential to produce novel metabolites with immense benefits for health industry. Cytotoxic and antimicrobial activities of endophytic fungi isolated from Bacop...

    Authors: Meenu Katoch, Gurpreet Singh, Sadhna Sharma, Nidhi Gupta, Payare Lal Sangwan and Ajit Kumar Saxena
    Citation: BMC Complementary and Alternative Medicine 2014 14:52
    Content type: Research article Published on:

  40. As health care has increased in complexity and health care teams have been offered as a solution, so too is there an increased need for stronger interprofessional collaboration. However the intraprofessional f...

    Authors: Marion McGregor, Aaron A Puhl, Christine Reinhart, H Stephen Injeyan and David Soave
    Citation: BMC Complementary and Alternative Medicine 2014 14:51
    Content type: Research article Published on:

  41. Chronic insomnia is a major public health problem affecting approximately 10% of adults. Use of meditation and yoga to develop mindful awareness (‘mindfulness training’) may be an effective approach to treat c...

    Authors: Amber Hubbling, Maryanne Reilly-Spong, Mary Jo Kreitzer and Cynthia R Gross
    Citation: BMC Complementary and Alternative Medicine 2014 14:50
    Content type: Research article Published on:

  42. Overproduction of free radicals and decreased antioxidant capacity are well-known risk factors for inflammatory bowel diseases. Gymnema sylvestre (GS) leaves extract is distinguished for its anti-diabetic, antiox...

    Authors: Abdulaziz M Aleisa, Salim S Al-Rejaie, Hatem M Abuohashish, Mohammed S Ola, Mihir Y Parmar and Mohammed M Ahmed
    Citation: BMC Complementary and Alternative Medicine 2014 14:49
    Content type: Research article Published on:

  43. Snakebite is a significant public health issue in tropical countries. In Brazil, some of the most common snake envenomations are from Bothrops. Bothrops bites trigger local and systemic effects including edema, p...

    Authors: Natália Tribuiani, Alexandro Mateus da Silva, Miriéle Cristina Ferraz, Magali Glauzer Silva, Ana Paula Guerreiro Bentes, Talita Signoreti Graziano, Marcio Galdino dos Santos, José Carlos Cogo, Eliana Aparecida Varanda, Francisco Carlos Groppo, Karina Cogo and Yoko Oshima-Franco
    Citation: BMC Complementary and Alternative Medicine 2014 14:48
    Content type: Research article Published on:

  44. Roots of Rumex hastatus (Polygonaceae) are traditionally used for the treatment of various ailments including liver and lung diseases. In this study, various solvent extracts of R. hastatus roots, like methanolic...

    Authors: Sumaira Sahreen, Muhammad Rashid Khan and Rahmat Ali Khan
    Citation: BMC Complementary and Alternative Medicine 2014 14:47
    Content type: Research article Published on:

  45. The use of complementary and alternative Medicine (CAM) has increased over the past two decades in Europe. Nonetheless, research investigating the evidence to support its use remains limited. The CAMbrella pro...

    Authors: Felix H Fischer, George Lewith, Claudia M Witt, Klaus Linde, Klaus von Ammon, Francesco Cardini, Torkel Falkenberg, Vinjar Fønnebø, Helle Johannessen, Bettina Reiter, Bernhard Uehleke, Wolfgang Weidenhammer and Benno Brinkhaus
    Citation: BMC Complementary and Alternative Medicine 2014 14:46
    Content type: Correspondence Published on:

  46. Antioxidant compounds like phenols and flavonoids scavenge free radicals and thus inhibit the oxidative mechanisms that lead to control degenerative and other diseases. The aim of this study was to investigate...

    Authors: Nandita Das, Md Ekramul Islam, Nusrat Jahan, Mohammad Saiful Islam, Alam Khan, Md Rafikul Islam and Mst Shahnaj Parvin
    Citation: BMC Complementary and Alternative Medicine 2014 14:45
    Content type: Research article Published on:

  47. The use of complementary and alternative medicine (CAM) is widespread and high utilization rates are associated with people who have chronic conditions like hypertension which management requires adherence to ...

    Authors: Irene A Kretchy, Frances Owusu-Daaku and Samuel Danquah
    Citation: BMC Complementary and Alternative Medicine 2014 14:44
    Content type: Research article Published on:

  48. Declining cognitive function is relatively common and increasingly prevalent. Studies have shown that different nutrients (e.g., Ginkgo biloba and vitamin E) appear to be effective at improving memory and conc...

    Authors: John E Lewis, Angelica B Melillo, Eduard Tiozzo, Lawrence Chen, Susanna Leonard, Mark Howell, Janelle Diaz, Kathy Gonzalez, Judi M Woolger, Janet Konefal, Elaine Paterson and David Barnes
    Citation: BMC Complementary and Alternative Medicine 2014 14:43
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2014 14:332

  49. Isoquercitrin, a flavonoid compound that is widely distributed in medicinal and dietary plants, possesses many biological activities, including inhibition of adipocyte differentiation. In this study, we invest...

    Authors: Jingxin Zhou, Hisae Yoshitomi, Tonghua Liu, Boxin Zhou, Wen Sun, Lingling Qin, Xiangyu Guo, Liansha Huang, Lili Wu and Ming Gao
    Citation: BMC Complementary and Alternative Medicine 2014 14:42
    Content type: Research article Published on:

  50. The increasing consumption of fruits and vegetables has contributed to the improvement of populational health, due in part, to the abundance of antioxidants in these foods. Antioxidants reduce the level of oxi...

    Authors: Elisângela Düsman, Alessandra Paim Berti, Rosinete Gonçalves Mariucci, Nilson Benedito Lopes, Lilian Tatiani Düsman Tonin and Veronica Elisa Pimenta Vicentini
    Citation: BMC Complementary and Alternative Medicine 2014 14:41
    Content type: Research article Published on:
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