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  1. Diabetic kidney disease affects approximately 40% of diabetic patients and is the leading cause of chronic kidney disease (CKD) worldwide. As a result, preventing renal complications in diabetic patients is cr...

    Authors: Parisa Veisi, Meysam Zarezade, Helya Rostamkhani and Zohreh Ghoreishi
    Citation: BMC Complementary Medicine and Therapies 2022 22:291
    Content type: Research Published on:

  2. The restorative effect of classical music was assessed on the cyclophosphamide-induced animal model of premature ovarian failure (POF).

    Authors: Nahideh Nazdikbin Yamchi, Mohammad Mojtaba Alizadeh Ashrafi, Hamed Abbasi, Farhad Amjadi, Mohammad Hossein Geranmayeh, Reza Shirazi, Amin Tamadon, Reza Rahbarghazi and Mahdi Mahdipour
    Citation: BMC Complementary Medicine and Therapies 2022 22:290
    Content type: Research Published on:

  3. Today, the increment in microbial resistance has guided the researches focus into new antimicrobial compounds or transmission systems. Escherichia coli (E. coli) is an opportunistic pathogen, producing a biofilm ...

    Authors: Mehran Nemattalab, Masoumeh Rohani, Mehdi Evazalipour and Zahra Hesari
    Citation: BMC Complementary Medicine and Therapies 2022 22:289
    Content type: Research Published on:

  4. Recent investigations suggested that anticancer agents may inhibit the progression of Alzheimer's disease (AD) pathology. Conyza dioscoridis (L.) was demonstrated to have anticancer, antioxidant, anti-inflammator...

    Authors: Adel A. Gomaa, Hanan S. M. Farghaly, Rania M. Makboul, Abeer M. Hussien and Mariam A. Nicola
    Citation: BMC Complementary Medicine and Therapies 2022 22:288
    Content type: Research Published on:

  5. Physical and mental health problems are becoming more serious among college students due to lifestyle changes and increased academic stress. Qigong exercise has been regarded as a potentially effective interve...

    Authors: Jianping Lin, Yi fang Gao, Yue Guo, Ming Li, Yuxiang Zhu, Ruoshi You, Shaoqing Chen and Shizhong Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:287
    Content type: Research Published on:

  7. Efficient delivery systems of Calophyllum inophyllum seed oil (CSO) in the form of nanoemulsion were optimised to enhance its stability and ensure its therapeutic efficiency as a potential agent for various biome...

    Authors: Elnaz Saki, Vinuthaa Murthy, Roshanak Khandanlou, Hao Wang, Johanna Wapling and Richard Weir
    Citation: BMC Complementary Medicine and Therapies 2022 22:285
    Content type: Research article Published on:

  8. Although Korean Red Ginseng (KRG) is safe, this finding was only evaluated in 3-mo-long studies. Its safety was verified through a 6-mo KRG administration clinical study, but long-term studies beyond 6 mo are ...

    Authors: Soo Kyung Park, Sung-Won Kim, Hwi Won Seo, Sun Hee Hyun, Jong-Su Kyung, Soo-Hyun Youn, Seung Ho So, Gyo In, Chae-Kyu Park, Eugene C. Yi, Chang-Kyun Han and Yong Yook Lee
    Citation: BMC Complementary Medicine and Therapies 2022 22:284
    Content type: Research Published on:

  9. Yoga-based exercise is a promising strategy for promoting healthy ageing, with the potential to reduce falls and increase physical, cognitive and psychological wellbeing. Teleyoga (real-time yoga provided via ...

    Authors: Abby Haynes, Heidi Gilchrist, Juliana S Oliveira, Catherine Sherrington and Anne Tiedemann
    Citation: BMC Complementary Medicine and Therapies 2022 22:283
    Content type: Research Published on:

  10. Quality of life (QoL) assessment has emerged as an important evaluation tool for therapeutic treatments. The positive impact of complementary music interventions on QoL has been demonstrated in the literature,...

    Authors: Angela Schell, Felix Wassmer, Lena Zaubitzer, Benedikt Kramer, Haneen Sadick, Nicole Rotter and Daniel Häussler
    Citation: BMC Complementary Medicine and Therapies 2022 22:282
    Content type: Research Published on:

  11. Zishen Yutai (ZSYT) pill, a patent Chinese medicine, has been widely used in the treatment of infertility, abortion, and adjunctive treatment of in vitro fertilization (IVF) for decades. Recently, the results ...

    Authors: Lei Dang, Chunbo Zhang, Biru Su, Na Ning, Qiuling Huang, Su Zhou, Meng Wu, Wenqing Ma, Man Wang, Pengfei Cui, Yan Li and Shixuan Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:281
    Content type: Research Published on:

  12. Bersama abyssinica is a common herb in Africa, with diverse medical uses in different areas. The plant is well-known in Tanzania for treating respiratory disorders such as TB, tonsillitis, bronchitis, and asthma,...

    Authors: Never Zekeya, Bertha Mamiro, Humphrey Ndossi, Rehema Chande Mallya, Mhuji Kilonzo, Alex Kisingo, Mkumbukwa Mtambo, Jafari Kideghesho and Jaffu Chilongola
    Citation: BMC Complementary Medicine and Therapies 2022 22:280
    Content type: Research Published on:

  13. Quercetin is an organic flavonoid present in several fruits and vegetables. The anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and neuroprotective properties demonstrated by th...

    Authors: Patrice Cunningham, Emma Patton, Brandon N. VanderVeen, Christian Unger, Ahmed Aladhami, Reilly T. Enos, Sarah Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy and Kandy T. Velázquez
    Citation: BMC Complementary Medicine and Therapies 2022 22:279
    Content type: Research Published on:

  14. Simiao pill module (SMM), a traditional Chinese medicine formula, has been widely used to treat gout and gouty arthritis. The goal of this study was to investigate the effects of SMM on epithelial-mesenchymal ...

    Authors: Guangxing Shui, Zheyi Cai, Feng Wang, Ting Chen, Xueyuan Huang, Yun Cai and Xiuhua Mi
    Citation: BMC Complementary Medicine and Therapies 2022 22:278
    Content type: Research Published on:

  16. Curcuminoids (CURs) are the principal ingredients of Curcuma longa L. [Zingiberaceae] (CL)—an herbal plant used in east Asia to alleviate pain and inflammation. Thus far, the therapeutic effects of CURs for knee ...

    Authors: Jie Feng, Zhao Li, Linling Tian, Panyun Mu, Yimei Hu, Feng Xiong and Xu Ma
    Citation: BMC Complementary Medicine and Therapies 2022 22:276
    Content type: Research Published on:

  17. Atopic dermatitis (AD) is a common inflammatory skin disease that compromises the skin's barrier function and capacity to retain moisture. Cnidii Fructus (CF), the dried fruits of Cnidium monnieri, has long been ...

    Authors: Shakeel Ahmad Khan, Ying Wu, Amy Sze-Man Li, Xiu-Qiong Fu and Zhi-Ling Yu
    Citation: BMC Complementary Medicine and Therapies 2022 22:275
    Content type: Research Published on:

  18. Prediabetes is a hypermetabolic syndrome with blood sugar levels falling between the normal and diabetes. People with prediabetes have a significantly increased chances of developing diabetes, cardiovascular a...

    Authors: Peng-Xiang Zhang, Lin Zeng, Lu Meng, Hui-Lin Li, Heng-Xia Zhao and De-Liang Liu
    Citation: BMC Complementary Medicine and Therapies 2022 22:274
    Content type: Study protocol Published on:

  19. Improper use of strychnine can cause death. The aim of this study was to identify and evaluate toxic mechanisms of action associated with active compounds in strychnine using a network toxicology approach, and...

    Authors: Jialin Dai, Jiangjin Liu, Maoxin Zhang, Yanni Yu and Jie Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:273
    Content type: Research Published on:

  20. Rosa rugosa cv. Plena, a cultivar of Rosa rugosa, has a history of more than 1300 years of application in both medicine and food in China. The essential oil of Rosa rugosa cv. Plena (PREO) is one of the most freq...

    Authors: Rifat Nowshin Raka, Ding Zhiqian, Yuan Yue, Qiao Luchang, Park Suyeon, Xiao Junsong and Wu Hua
    Citation: BMC Complementary Medicine and Therapies 2022 22:272
    Content type: Research Published on:

  21. The increased global incidence of myopia requires the establishment of therapeutic approaches. This study aimed to investigate the effect of Fallopia Japonica (FJ) and Prunella vulgaris (PV) extract on myopia cau...

    Authors: Chih-Sheng Chen, Yu-An Hsu, Chia-Hung Lin, Yao-Chien Wang, En-Shyh Lin, Ching-Yao Chang, Jamie Jiin-Yi Chen, Ming-Yen Wu, Hui-Ju Lin and Lei Wan
    Citation: BMC Complementary Medicine and Therapies 2022 22:271
    Content type: Research Published on:

  22. Cistanche tubulosa is an editable and medicinal traditional Chinese herb and phenylethanoid glycosides are its major components, which have shown various beneficial effects such as anti-tumor, anti-oxidant and ne...

    Authors: Dilinazi Abudujilile, Weilan Wang, Alimu Aimaier, Lili Chang, Yuliang Dong, Yiye Wang, Xu Fan, Yu Ma, Yongli Wang, Dilinigeer Ziyayiding, Yuan Ma, Jie Lv and Jinyao Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:270
    Content type: Research Published on:

  23. Monosodium glutamate (MSG) is a food ingredient that is increasingly used commercially. MSG leads to oxidative stress, consequently suppressing steroid hormone production that causes defects in male reproducti...

    Authors: Farhad Koohpeyma, Fatemeh Gholizadeh, Hannaneh Hafezi, Mehri Hajiaghayi, Morvarid Siri, Shaghayegh Allahyari, Mohammad Hasan Maleki, Naeimehossadat Asmarian, Elahe Bayat and Sanaz Dastghaib
    Citation: BMC Complementary Medicine and Therapies 2022 22:269
    Content type: Research Published on:

  24. The WHO recommends artemisinin-based combination regimens for uncomplicated Plasmodium falciparum malaria. One such combination is artemisinin-piperaquine tablets (ATQ). ATQ has outstanding advantages in anti-mal...

    Authors: Xiaobo Li, Yueming Yuan, Yingyi Chen, Li Ru, Zheng Yuan, Zhiyong Xu, Qin Xu, Jianping Song, Guoming Li and Changsheng Deng
    Citation: BMC Complementary Medicine and Therapies 2022 22:268
    Content type: Research Published on:

  26. The emergence of antimalarial drug resistance encourages the search for new antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a medicinal plant that is used in traditional Thai ...

    Authors: Prapaporn Chaniad, Arnon Chukaew, Apirak Payaka, Arisara Phuwajaroanpong, Tachpon Techarang, Walaiporn Plirat and Chuchard Punsawad
    Citation: BMC Complementary Medicine and Therapies 2022 22:266
    Content type: Research Published on:

  27. Huntington’s disease manifests due to abnormal CAG trinucleotide expansion, in the first exon of the Huntingtin gene and disease progression involves genetic, immune, and environmental components. The pathogenesi...

    Authors: Surabhi Singh and Madhu G. Tapadia
    Citation: BMC Complementary Medicine and Therapies 2022 22:265
    Content type: Research article Published on:

  28. The development of multidrug resistance (MDR) associated with the overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes antifungal therapies. The urgent need for novel agents able to ...

    Authors: Florimar Gil, Jerónimo Laiolo, Brayan Bayona-Pacheco, Richard D. Cannon, Antonio Ferreira-Pereira and María Cecilia Carpinella
    Citation: BMC Complementary Medicine and Therapies 2022 22:264
    Content type: Research Published on:

  29. Complementary medicine (CM) is frequently used by patients, but little is known about the usage of CM in surgical patients. The study aimed to elucidate the relevance of CM in surgery.

    Authors: Ann-Kathrin Lederer, Yvonne Samstag, Thomas Simmet, Tatiana Syrovets and Roman Huber
    Citation: BMC Complementary Medicine and Therapies 2022 22:263
    Content type: Research Published on:

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:304

  30. Diabetic nephropathy (DN) is one of the most important complications of type 2 diabetes (T2DM). Oxidative stress and inflammatory cytokines play an essential role in the development and progression of DN. Desp...

    Authors: Asma Jaafarinia, Behzad Kafami, Adeleh Sahebnasagh and Fatemeh Saghafi
    Citation: BMC Complementary Medicine and Therapies 2022 22:262
    Content type: Research Published on:

  31. As the largest organ, the skin has been frequently affected by trauma, chemical materials, toxins, bacterial pathogens, and free radicals. Recently, many attempts have been made to develop natural nanogels tha...

    Authors: Fatemeh Rasti, Yaser Yousefpoor, Abbas Abdollahi, Mojdeh Safari, Ghazaal Roozitalab and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:261
    Content type: Research Published on:

  32. Authors: Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa‑Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani and Gaber El‑Saber Batiha
    Citation: BMC Complementary Medicine and Therapies 2022 22:260
    Content type: Correction Published on:

    The original article was published in BMC Complementary Medicine and Therapies 2022 22:227

  33. The leaf of Ceylon cinnamon (true cinnamon) is traditionally claimed for a variety of health benefits. However, reported scientific information is scanty and needs urgent attention for value addition.

    Authors: Walimuni Prabhashini Kaushalya Mendis Abeysekera, Galbada Arachchige Sirimal Premakumara, Wanigasekera Daya Ratnasooriya and Walimuni Kanchana Subhashini Mendis Abeysekera
    Citation: BMC Complementary Medicine and Therapies 2022 22:259
    Content type: Research Published on:

  34. The emergence of drug resistance among pathogens has resulted in renewed interest in bioprospecting for natural microbial products.

    Authors: Tsolanku Sidney Maliehe, Melusi Mbambo, Londeka Sibusisiwe Ngidi, Jabulani Siyabonga Emmanuel Shandu, Ofentse Jacob Pooe, Peter Masoko and Tlou Nelson Selepe
    Citation: BMC Complementary Medicine and Therapies 2022 22:258
    Content type: Research Published on:

  35. Baicalin is a generally available flavonoid with potent biological activity. The present study aimed to assess the underlying mechanism of baicalin in treatment of atherosclerosis (AS) with the help of network...

    Authors: Mingshuang Li and Conglin Ren
    Citation: BMC Complementary Medicine and Therapies 2022 22:257
    Content type: Research Published on:

  36. Propolis extracted from beehives has been conferred with natural antimicrobial and antioxidant properties. Hence, it has been recommended as a wound healing therapy. This study investigated the additive value ...

    Authors: Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar and Hoda A. Elkhenany
    Citation: BMC Complementary Medicine and Therapies 2022 22:256
    Content type: Research Published on:

  37. Diabetic wounds are one of the most important issues in diabetic patients. It seems that Juglans regia L. leaf with antioxidant and anti-inflammatory potentials can be profitable for healing of diabetic wounds. T...

    Authors: Davood Nasiry, Ali Reza Khalatbary, Alireza Ghaemi, Mohammad Ali Ebrahimzadeh and Mohammad Hossein Hosseinzadeh
    Citation: BMC Complementary Medicine and Therapies 2022 22:255
    Content type: Research Published on:

  38. Endometriosis is a common gynecological disease, and its underlying mechanisms remain elusive. Patients are at a higher risk of recurrence after surgery or drug withdrawal. In this study, to identify a potenti...

    Authors: Junde Zhao, Juntao Wang, Jinxing Liu, Shuling Li, Pengfei Liu and Xiaodan Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:254
    Content type: Research Published on:

  39. Epimedii has long been used as a traditional medicine in Asia for the treatment of various common diseases, including Alzheimer's disease, cancer, erectile dysfunction, and stroke. Studies have reported the am...

    Authors: Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li and De-xi Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:253
    Content type: Research Published on:

  40. Traditional, complementary and alternative medicine (TCAM) is used to treat a broad range of conditions. In low- and middle-income countries (LMICs), TCAM use is particularly common among those with low socio-...

    Authors: Lia M. Palileo-Villanueva, Benjamin Palafox, Arianna Maever L. Amit, Veincent Christian F. Pepito, Fadhlina Ab-Majid, Farnaza Ariffin, Dina Balabanova, Mohamad-Rodi Isa, Nafiza Mat-Nasir, Mazapuspavina My, Alicia Renedo, Maureen L. Seguin, Khalid Yusoff, Antonio L. Dans and Martin Mckee
    Citation: BMC Complementary Medicine and Therapies 2022 22:252
    Content type: Research Published on:

  41. Complementary and Integrative Medicine (CIM) is often taken up by individuals seeking relief from different diseases. This study investigates the prevalence and associated factors of CIM use in patients with C...

    Authors: Mohammad Mahdi Parvizi, Sedigheh Forouhari, Reza Shahriarirad, Sepehr Shahriarirad, Ryan D Bradley and Leila Roosta
    Citation: BMC Complementary Medicine and Therapies 2022 22:251
    Content type: Research Published on:

  42. Akt and mTOR are aberrantly activated in cancers and targeting these proteins are interesting for cancer drug discovery. Napabucasin (NB), a phytochemical compound, has been reported as potential anti-cancer a...

    Authors: Korrakod Petsri, Sunisa Thongsom, Satapat Racha, Supakarn Chamni, Saresa Jindapol, Nantawat Kaekratoke, Hongbin Zou and Pithi Chanvorachote
    Citation: BMC Complementary Medicine and Therapies 2022 22:250
    Content type: Research Published on:

  43. One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes, α-amylase, and α-glucosidases, in the diges...

    Authors: Haimanot Mitiku, Tae Yang Kim, Hanna Kang, Emmanouil Apostolidis, Jung-Yun Lee and Young-In Kwon
    Citation: BMC Complementary Medicine and Therapies 2022 22:249
    Content type: Research Published on:

  44. Complementary medicine therapists such as traditional acupuncturists are a large resource for supporting public health targets to improve health behaviours. Our objectives were to determine the prevalence and ...

    Authors: J. Pinto, K. Bradbury, D. Newell and F. L. Bishop
    Citation: BMC Complementary Medicine and Therapies 2022 22:248
    Content type: Research Published on:

  45. Black salve is a controversial complementary and alternative medicine (CAM) associated with skin toxicity and skin cancer treatment failures. Black salve formulations vary between manufacturers and contain a n...

    Authors: Andrew Croaker, Arie Davis, Anthony Carroll, Lei Liu and Stephen P. Myers
    Citation: BMC Complementary Medicine and Therapies 2022 22:247
    Content type: Research Published on:

  46. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12906-016-1470-9.

    Authors: Vikas Kumar, Prakash Chandra Bhatt, Kalicharan Sharma, Mahfoozur Rahman, Dinesh Kumar Patel, Nikunj Sethi, Atul Kumar, Nikhil Kumar Sachan, Gaurav Kaithwas, F. A. Al-abbasi, Firoz Anwar and Amita Verma
    Citation: BMC Complementary Medicine and Therapies 2022 22:246
    Content type: Retraction Note Published on:

  47. Disseminated intravascular coagulation (DIC) is a syndrome characterized by coagulopathy, microthrombus, and multiple organ failure. The complement system in DIC is overactivated, and the functions of compleme...

    Authors: Qi-Yun Zhang, Jing Guo, Lin Xu, Ying Wei, Shu-Ting Zhou, Qing-Yu Lu, Li Guo and Qian-Yun Sun
    Citation: BMC Complementary Medicine and Therapies 2022 22:245
    Content type: Research Published on:

  48. Traditional herbs played a crucial role in the health care of the Hakka people. However, studies to identify these traditional herbs are few. Here we document and assess the potential of these plants for treat...

    Authors: Haibo Hu, Yanfang Yang, Abdallah Aissa, Volkan Tekin, Jialin Li, Sujogya Kumar Panda, Hao Huang and Walter Luyten
    Citation: BMC Complementary Medicine and Therapies 2022 22:244
    Content type: Research article Published on:

  49. Cardiovascular diseases cause the death of 17.5 million people every year. Cardiac catheterization is an invasive diagnostic exam that allows treatment followed by the examination and can cause some complicati...

    Authors: Kauanny Vitoria Gurgel dos Santos, Karena Cristina da Silva Leal, Louise Constancia de Melo Alves Silva, Kleyton Santos de Medeiros, Alexsandra Rodrigues Feijão, Maria do Carmo de Oliveira, Daniele Vieira Dantas and Rodrigo Assis Neves Dantas
    Citation: BMC Complementary Medicine and Therapies 2022 22:243
    Content type: Study protocol Published on:

  50. Ecklonia cava is an edible marine brown alga harvested from the ocean that is widely consumed in Asian countries as a health-promoting medicinal food The objective of the present study is to evaluate the anti-as...

    Authors: Kyung Hee Lee, Yeo Jin Jang, Woon Sang Hwang, Ki Sun Kwon, Wha Young Lee, Jeanman Kim, Sung Phil Kim and Mendel Friedman
    Citation: BMC Complementary Medicine and Therapies 2022 22:242
    Content type: Research Published on:
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