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  1. Carpobrotus edulis (Mesembryanthemaceae), also known as igcukuma in Xhosa language is a medicinal plant used by the traditional healers to treat common infections in HIV/AIDS patients. Based on this information,...

    Authors: Beauty E Omoruyi, Graeme Bradley and Anthony J Afolayan
    Citation: BMC Complementary and Alternative Medicine 2012 12:215
    Content type: Research article Published on:

  2. Dengue is a serious arboviral disease currently with no effective antiviral therapy or approved vaccine available. Therefore, finding the effective compound against dengue virus (DENV) replication is very impo...

    Authors: Keivan Zandi, Boon-Teong Teoh, Sing-Sin Sam, Pooi-Fong Wong, Mohd Rais Mustafa and Sazaly AbuBakar
    Citation: BMC Complementary and Alternative Medicine 2012 12:214
    Content type: Research article Published on:

  3. Diseases caused by microorganisms and parasites remain a major challenge globally and particularly in sub-Saharan Africa to man and livestock. Resistance to available antimicrobials and the high cost or unavai...

    Authors: Mathew Adamu, Vinasan Naidoo and Jacobus N Eloff
    Citation: BMC Complementary and Alternative Medicine 2012 12:213
    Content type: Research article Published on:

  4. Irritable bowel syndrome is a chronic condition with no known cure. Many sufferers seek complementary and alternative medicine including homeopathic treatment. However there is much controversy as to the effec...

    Authors: Emily J Peckham, Clare Relton, Jackie Raw, Clare Walters, Kate Thomas and Christine Smith
    Citation: BMC Complementary and Alternative Medicine 2012 12:212
    Content type: Study protocol Published on:

  5. The use of complementary and alternative medicine (CAM) continues to increase in Taiwan. This study examined the use of CAM and beliefs about CAM as expressed by patients with traumatic brain injury (TBI) in T...

    Authors: Bih-Shya Gau, Hsiao-Ling Yang, Sheng-Jean Huang and Meei-Fang Lou
    Citation: BMC Complementary and Alternative Medicine 2012 12:211
    Content type: Research article Published on:

  6. Angiogenesis plays a critical role in embryonic development and various physiological processes. However, excessive angiogenesis is associated with several pathological conditions including cancer. Pithecellobium...

    Authors: Nahdzatul Syima Muslim, Zeyad D Nassar, Abdalrahim FA Aisha, Armaghan Shafaei, Norshirin Idris, AminMalikShahAbdul Majid and Zhari Ismail
    Citation: BMC Complementary and Alternative Medicine 2012 12:210
    Content type: Research article Published on:

  7. Multiple sclerosis (MS) is a complex autoimmune disease mediated by an immune response to central nervous system antigens. Modern immunomodulatory therapies, however, do not ameliorate many of the symptoms, su...

    Authors: Juan G Quispe-Cabanillas, Alfredo Damasceno, Felipe von Glehn, Carlos O Brandão, Benito P Damasceno, Wanderley D Silveira and Leonilda MB Santos
    Citation: BMC Complementary and Alternative Medicine 2012 12:209
    Content type: Research article Published on:

  8. The anticancer and immunomodulatory activity of mung bean sprouts (MBS) and the underlying mechanisms against human cervical and hepatocarcinoma cancer cells were explored.

    Authors: Rand R Hafidh, Ahmed S Abdulamir, Fatimah Abu Bakar, Farid Azizi Jalilian, Faridah Abas and Zamberi Sekawi
    Citation: BMC Complementary and Alternative Medicine 2012 12:208
    Content type: Research article Published on:

  9. There have been a few but not precise surveys of the current status of traditional Japanese Kampo education at medical schools in Japan. Our aim was to identify problems and suggest solutions for a standardize...

    Authors: Makoto Arai, Shuichi Katai, Shin-ichi Muramatsu, Takao Namiki, Toshihiko Hanawa and Shun-ichiro Izumi
    Citation: BMC Complementary and Alternative Medicine 2012 12:207
    Content type: Research article Published on:

  13. The dibenzylbutyrolactone lignan (−)-hinokinin (HK) was derived by partial synthesis from (−)-cubebin, isolated from the dry seeds of the pepper, Piper cubeba. Considering the good trypanosomicidal activity of HK...

    Authors: Flávia Aparecida Resende, Lilian Cristina Barbosa, Denise Crispim Tavares, Mariana Santoro de Camargo, Karen Cristina de Souza Rezende, Márcio Luis de Andrade e Silva and Eliana Aparecida Varanda
    Citation: BMC Complementary and Alternative Medicine 2012 12:203
    Content type: Research article Published on:

  14. Drugs used both in classical chemotherapy and the more recent targeted therapy do not have cancer cell specificity and, hence, cause severe systemic side effects. Tumors also develop resistance to such drugs d...

    Authors: Nasser M Al-Daghri, Majed S Alokail, Khalid M Alkharfy, Abdul Khader Mohammed, Sherif H Abd-Alrahman, Sobhy M Yakout, Osama E Amer and Soundararajan Krishnaswamy
    Citation: BMC Complementary and Alternative Medicine 2012 12:202
    Content type: Research article Published on:

  15. Previous studies have demonstrated that the consumption of green tea inhibits the growth of various cancers. Most cancers are believed to be initiated from and maintained by a small population of cancer stem-l...

    Authors: Chien-Hung Lin, Yao-An Shen, Peir-Haur Hung, Yuan-Bin Yu and Yann-Jang Chen
    Citation: BMC Complementary and Alternative Medicine 2012 12:201
    Content type: Research article Published on:

  16. This study evaluated, using in vitro assays, the antibacterial, antioxidant, and tyrosinase-inhibition activities of methanolic extracts from peels of seven commercially grown pomegranate cultivars.

    Authors: Olaniyi A Fawole, Nokwanda P Makunga and Umezuruike Linus Opara
    Citation: BMC Complementary and Alternative Medicine 2012 12:200
    Content type: Research article Published on:

  17. In folk medicine, the aerial part of Crytotaenia japonica Hassk. (CJ), is applied for treatment of the common cold, cough, urinary problems, pneumonia, and skin rashes. In this paper, the in vitro and in vivo ant...

    Authors: Hee Kang, Tae-Sun Bang, Ji-Won Lee, Jae-Hwan Lew, Seok Hyun Eom, Kyungjin Lee and Ho-Young Choi
    Citation: BMC Complementary and Alternative Medicine 2012 12:199
    Content type: Research article Published on:

  18. Over 30% of individuals use natural health products (NHPs) for osteoarthritis-related pain. The Deficit Model for the Public Understanding of Science suggests that if individuals are given more information (es...

    Authors: Teresa Tsui, Heather Boon, Andreas Boecker, Natasha Kachan and Murray Krahn
    Citation: BMC Complementary and Alternative Medicine 2012 12:198
    Content type: Research article Published on:

  19. Traditional Chinese medicine (TCM) has been used to treat chronic obstructive pulmonary disease (COPD) for many years. This study aimed to evaluate the efficacy and safety of the comprehensive therapy based on...

    Authors: Su-yun Li, Jian-sheng Li, Ming-hang Wang, Yang Xie, Xue-qing Yu, Zi-kai Sun, Li-jun Ma, Wei Zhang, Hai-long Zhang, Fan Cao and Ying-chao Pan
    Citation: BMC Complementary and Alternative Medicine 2012 12:197
    Content type: Research article Published on:

  20. Microglial activation plays an important role in neurodegenerative diseases by producing several pro-inflammatory enzymes and pro-inflammatory cytokines. Lipopolysaccharide (LPS)-induced inflammation leads to ...

    Authors: Kang-Woo Lee, So Young Jung, Sun-Mi Choi and Eun Jin Yang
    Citation: BMC Complementary and Alternative Medicine 2012 12:196
    Content type: Research article Published on:

  21. Many cancers contain cell subpopulations that display characteristics of stem cells. Because these cancer stem cells (CSCs) appear to provide resistance to chemo-radiation therapy, development of therapeutic a...

    Authors: Taghreed N Almanaa, Michael E Geusz and Roudabeh J Jamasbi
    Citation: BMC Complementary and Alternative Medicine 2012 12:195
    Content type: Research article Published on:

  22. Propolis is a natural product of plant resins collected by honeybees (Apis mellifera) from various plant sources. Our previous studies indicated that propolis sensitivity is dependent on the mitochondrial functio...

    Authors: Patrícia Alves de Castro, Marcela Savoldi, Diego Bonatto, Iran Malavazi, Maria Helena S Goldman, Andresa A Berretta and Gustavo Henrique Goldman
    Citation: BMC Complementary and Alternative Medicine 2012 12:194
    Content type: Research article Published on:

  23. The overall prevalence of complementary medicine (CM) use among adults in the United States with diabetes has been examined both in representative national samples and in more restricted populations. However, ...

    Authors: Richard L Nahin, Danita Byrd-Clark, Barbara J Stussman and Nilesh Kalyanaraman
    Citation: BMC Complementary and Alternative Medicine 2012 12:193
    Content type: Research article Published on:

  24. Brazilian green propolis is reported to have wide range of biological properties including antibacterial, anti-inflammatory, anti-influenza, and antioxidant activities. In the digestive system, a protective ef...

    Authors: Mamoru Kakino, Hiroshi Izuta, Kazuhiro Tsuruma, Yoko Araki, Masamitsu Shimazawa, Kenji Ichihara and Hideaki Hara
    Citation: BMC Complementary and Alternative Medicine 2012 12:192
    Content type: Research article Published on:

  25. This paper proposes a novel model for homeopathic remedy action on living systems. Research indicates that homeopathic remedies (a) contain measurable source and silica nanoparticles heterogeneously dispersed ...

    Authors: Iris R Bell and Mary Koithan
    Citation: BMC Complementary and Alternative Medicine 2012 12:191
    Content type: Debate Published on:

  26. Nuna Kadugu (NK), a Siddha medicine prepared from leaves and fruits of Morinda Pubescens, used for the treatment of various skin diseases. Though NK has been widely used for several decades, no scientific report ...

    Authors: Ramaswamy Selvaratnam Ramaswamy, Nettam Prathyusha, Ruthiramoorthi Saranya, Haridass Sumathy, Kutuva Tulasi Mohanavalli, Raju Jyothi Priya, Jayakothanda Ramaswamy Venkhatesh, Chidambaram Saravana Babu, Kumarasamy Manickavasakam and Sadagopan Thanikachalam
    Citation: BMC Complementary and Alternative Medicine 2012 12:190
    Content type: Research article Published on:

  27. Our previous studies indicated that oxidative stress up-regulated the expression of β-amyloid precursor protein cleavage enzyme-1 (BACE1) in rat retina. Pharmacological reports have shown Timosaponin-BII, a pu...

    Authors: Ju-Fang Huang, Lei Shang, Pei Liu, Meng-Qi Zhang, Shuang Chen, Dan Chen, Chun-Ling Fan, Hui Wang and Kun Xiong
    Citation: BMC Complementary and Alternative Medicine 2012 12:189
    Content type: Research article Published on:

  28. Diabetes is one of the risk factors for cognitive deficits such as Alzheimer’s disease. To obtain a better understanding of the anti-dementia effect of chotosan (CTS), a Kampo formula, we investigated its effe...

    Authors: Qi Zhao, Yimin Niu, Kinzo Matsumoto, Koichi Tsuneyama, Ken Tanaka, Takeshi Miyata and Takako Yokozawa
    Citation: BMC Complementary and Alternative Medicine 2012 12:188
    Content type: Research article Published on:

  29. Selaginella convoluta (Arn.) Spring (Selaginellaceae), commonly known as “jericó”, is a medicinal plant found in northeastern Brazil. S. convoluta is used in folk medicine as an antidepressant, aphrodisiac, diur...

    Authors: Pedro Guilherme S de Sá, Xirley Pereira Nunes, Julianeli Tolentino de Lima, JoséAlvesdeSiqueira Filho, André Paviotti Fontana, Jullyana de Souza Siqueira, Lucindo José Quintans-Júnior, Patrícia Kauanna Fonseca Damasceno, Carla Rodrigues Cardoso Branco, Alexsandro Branco and JacksonRobertoGuedesdaSilva Almeida
    Citation: BMC Complementary and Alternative Medicine 2012 12:187
    Content type: Research article Published on:

  30. Noni fruit is widely consumed in tropical regions of Indonesia to the Hawaiian Islands. The noni plant has a long history of use as a medicinal plant to treat a wide variety of ailments including CNS disorders...

    Authors: Vijayapandi Pandy, Megala Narasingam and Zahurin Mohamed
    Citation: BMC Complementary and Alternative Medicine 2012 12:186
    Content type: Research article Published on:

  31. Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from the Thai medicinal plant Trichosanthes cucumerina L., has been reported to have several biological activities including anti-inflamma...

    Authors: Suwit Duangmano, Phorntip Sae-lim, Apichart Suksamrarn, Frederick E Domann and Pimpicha Patmasiriwat
    Citation: BMC Complementary and Alternative Medicine 2012 12:185
    Content type: Research article Published on:

  32. Cupping is used in various traditional medicine forms to relieve pain in musculoskeletal diseases. The aim of this study was to investigate the effectiveness of cupping in relieving the symptoms of knee osteoa...

    Authors: Michael Teut, Stefan Kaiser, Miriam Ortiz, Stephanie Roll, Sylvia Binting, Stefan N Willich and Benno Brinkhaus
    Citation: BMC Complementary and Alternative Medicine 2012 12:184
    Content type: Research article Published on:

  33. Complementary medicines (CMs) are widely used by the Australian public, and pharmacies are major suppliers of these medicines. The integration of CMs into pharmacy practice is well documented, but the behaviou...

    Authors: Sarah E Culverhouse and Hans Wohlmuth
    Citation: BMC Complementary and Alternative Medicine 2012 12:183
    Content type: Research article Published on:

  34. United States Army Soldiers regularly use dietary supplements (DS) to promote general health, enhance muscle strength, and increase energy, but limited scientific evidence supports the use of many DS for these...

    Authors: Christina E Carvey, Emily K Farina and Harris R Lieberman
    Citation: BMC Complementary and Alternative Medicine 2012 12:182
    Content type: Research article Published on:

  35. Sonchus asper (L.) Hill, (Asteraceae) is used in Pakistan as a traditional (“folk”) medicine for the treatment of hormonal disorders and oxidative stress. The present study was aimed to evaluate the efficacy of

    Authors: Rahmat Ali Khan
    Citation: BMC Complementary and Alternative Medicine 2012 12:181
    Content type: Research article Published on:

  36. Patients with stroke have various syndromes and symptoms. Through pattern identification (PI), traditional Korean medicine (TKM) classifies the several syndromes and symptoms of stroke patients into five categ...

    Authors: Ji Hye Lim, Mi Mi Ko, Tae-Woong Moon, Min Ho Cha and Myeong Soo Lee
    Citation: BMC Complementary and Alternative Medicine 2012 12:180
    Content type: Research article Published on:

  37. Oral cancers although preventable, possess a low five-year survival rate which has remained unchanged over the past three decades. In an attempt to find a more safe, affordable and effective treatment option, ...

    Authors: Lionel LA In, Norhafiza M Arshad, Halijah Ibrahim, Mohamad Nurul Azmi, Khalijah Awang and Noor Hasima Nagoor
    Citation: BMC Complementary and Alternative Medicine 2012 12:179
    Content type: Research article Published on:

  38. Rutin is a polyphenolic natural flavonoid which possesses antioxidant and anticancer activity. In the present study the hepatoprotective effect of rutin was evaluated against carbon tetrachloride (CCl4)-induced l...

    Authors: Rahmat A Khan, Muhammad R Khan and Sumaira Sahreen
    Citation: BMC Complementary and Alternative Medicine 2012 12:178
    Content type: Research article Published on:

  39. There is no available information on physicochemical and antioxidant properties on Bangladeshi honey. We investigated five different monofloral and three different multifloral honey samples collected from diff...

    Authors: Asiful Islam, Ibrahim Khalil, Nazmul Islam, Mohammed Moniruzzaman, Abdul Mottalib, Siti Amrah Sulaiman and Siew Hua Gan
    Citation: BMC Complementary and Alternative Medicine 2012 12:177
    Content type: Research article Published on:

  40. In the present study, we tested a 50% ethanolic extract of Orthosiphon stamineus plants and its isolated bioactive compound with respect to their α-glucosidase and α-amylase inhibitory activities.

    Authors: Elsnoussi Ali Hussin Mohamed, Mohammad Jamshed Ahmad Siddiqui, Lee Fung Ang, Amirin Sadikun, Sue Hay Chan, Soo Choon Tan, Mohd Zaini Asmawi and Mun Fei Yam
    Citation: BMC Complementary and Alternative Medicine 2012 12:176
    Content type: Research article Published on:

  41. Withania somnifera, also known as ashwagandha, is an important herb in ayurvedic and indigenous medical systems. The present study was designed to evaluate the antioxidant and antibacterial activities of an 80% ...

    Authors: Nadia Alam, Monzur Hossain, Md Abdul Mottalib, Siti Amrah Sulaiman, Siew Hua Gan and Md Ibrahim Khalil
    Citation: BMC Complementary and Alternative Medicine 2012 12:175
    Content type: Research article Published on:

  42. The essential oil from Fructus Alpiniae zerumbet (FAZ) is its principal bioactive ingredient, and is widely used in Miao folk herbs in Guizhou province for the treatment of gastrointestinal and cardiovascular dis...

    Authors: Xiang-chun Shen, Ling Tao, Wan-kui Li, Yan-yan Zhang, Hong Luo and Yu-yi Xia
    Citation: BMC Complementary and Alternative Medicine 2012 12:174
    Content type: Research article Published on:

  43. The main aim of this study is to evaluate the antioxidant and anti-inflammatory properties of forty four traditional Chinese medicinal herbal extracts and to examine these activities in relation to their antio...

    Authors: Anjaneya S Ravipati, Lin Zhang, Sundar Rao Koyyalamudi, Sang Chul Jeong, Narsimha Reddy, John Bartlett, Paul T Smith, Kirubakaran Shanmugam, Gerald Münch, Ming Jie Wu, Manavalan Satyanarayanan and Balaram Vysetti
    Citation: BMC Complementary and Alternative Medicine 2012 12:173
    Content type: Research article Published on:

  44. Mistletoe (Viscum album L.) extracts are widely used in complementary cancer therapy. Aim of this study was to evaluate safety and efficacy of a standardized mistletoe extract (abnobaVISCUM® Quercus, aVQ) in p...

    Authors: Kab-Choong Kim, Jeong-Hwan Yook, Jürgen Eisenbraun, Byung-Sik Kim and Roman Huber
    Citation: BMC Complementary and Alternative Medicine 2012 12:172
    Content type: Research article Published on:

  45. This study aims to investigate anti-inflammatory effect of ethanolic extract of Myagropsis myagroides (EMM) in the lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages and the phorbol 12-myristate 13-acetate...

    Authors: Eun-Ji Joung, Min-Sup Lee, Ji-Woong Choi, Jong-Soon Kim, Taisun Shin, Bok-Mi Jung, Na Young Yoon, Chi-Won Lim, Jae-Il Kim and Hyeung-Rak Kim
    Citation: BMC Complementary and Alternative Medicine 2012 12:171
    Content type: Research article Published on:

  46. A dried root of Aristolochia tagala Cham. (ATC) is often used in Thai traditional medicine as an antipyretic, anti-inflammatory agent, muscle relaxant, appetite-enhancing agent, and analeptic. Homnawakod, an impo...

    Authors: Pinpat Tripatara, Winita Onlamul, Suksalin Booranasubkajorn, Jantanee Wattanarangsan, Sukit Huabprasert, Natchagorn Lumlerdkij, Pravit Akarasereenont and Tawee Laohapand
    Citation: BMC Complementary and Alternative Medicine 2012 12:170
    Content type: Research article Published on:

  47. Mycoplasmosis is a common infection in human and veterinary medicine, and is associated with chronic inflammation and high morbidity. Mycoplasma species are often intrinsically resistant to many conventional anti...

    Authors: Amanda V Arjoon, Charlotte V Saylor and Meghan May
    Citation: BMC Complementary and Alternative Medicine 2012 12:169
    Content type: Research article Published on:

  48. The leaves and root of Flabellaria paniculata (Malpighiaceae) are frequently used in the treatment of wounds and ulcers in Nigerian folk medicine. The purpose of this study was to compare the effect of ethanolic ...

    Authors: Margaret O Sofidiya, Lilian Agufobi, Abidemi J Akindele, Johnson A Olowe and Oluwole B Familoni
    Citation: BMC Complementary and Alternative Medicine 2012 12:168
    Content type: Research article Published on:

  49. Difficulty in controlling attention can lead to mental fatigue in the healthy population. We identified one trial reporting a benefit in patients’ attention using a homeopathic formula preparation. One compone...

    Authors: Michael Emmans Dean, Raj Karsandas, J Martin Bland, Debbie Gooch and Hugh MacPherson
    Citation: BMC Complementary and Alternative Medicine 2012 12:167
    Content type: Research article Published on:

  50. The aqueous-methanolic extract of Amaranthus spinosus (A. spinosus Linn.,) whole plant, was studied for its laxative, spasmolytic and bronchodilator activities to validate some of its medicinal uses.

    Authors: Mueen Ahmad Chaudhary, Imran Imran, Samra Bashir, Malik Hassan Mehmood, Najeeb-ur Rehman and Anwarul-Hassan Gilani
    Citation: BMC Complementary and Alternative Medicine 2012 12:166
    Content type: Research article Published on:
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