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  1. The development and growth of colorectal cancer based on constitutive activation of numerous signaling pathways that stimulate proliferation and metastasis. Plant-derived agents excel by targeting multiple asp...

    Authors: Marta Woźniak, Sebastian Makuch, Kinga Winograd, Jerzy Wiśniewski, Piotr Ziółkowski and Siddarth Agrawal

    Citation: BMC Complementary Medicine and Therapies 2020 20:141

    Content type: Research article

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  2. Ecdysteroids are polyhydroxylated steroids present in invertebrates and plants. 20-Hydroxyecdysone (20E) is the most common and the main biologically active compound of ecdysteroids. Previous studies have demo...

    Authors: Jariya Buniam, Natsasi Chukijrungroat, Yupaporn Rattanavichit, Juthamard Surapongchai, Jittima Weerachayaphorn, Tepmanas Bupha-Intr and Vitoon Saengsirisuwan

    Citation: BMC Complementary Medicine and Therapies 2020 20:140

    Content type: Research article

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  3. In South Africa naturopaths have been practising for over half a century. Over this period, changes in legislation have resulted in different levels of training and registration processes - which has impacted ...

    Authors: Wendy Ericksen-Pereira, Nicolette V. Roman and Rina Swart

    Citation: BMC Complementary Medicine and Therapies 2020 20:139

    Content type: Research article

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  4. This is the second part of a large spectrum systematic review which aims to identify and assess the evidence for the efficacy of non-pharmacological acupuncture techniques in the treatment of chronic obstructi...

    Authors: Carles Fernández-Jané, Jordi Vilaró, Yutong Fei, Congcong Wang, Jianping Liu, Na Huang, Ruyu Xia, Xia Tian, Ruixue Hu, Lingzi Wen, Mingkun Yu, Natàlia Gómara-Toldrà, Mireia Solà-Madurell and Mercè Sitjà-Rabert

    Citation: BMC Complementary Medicine and Therapies 2020 20:138

    Content type: Research article

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  5. Considerable number of patients, including Ebola survivors, in Sierra Leone, are using traditional and complementary medicine (T&CM). Healthcare providers’ (HCPs) views about T&CM is crucial in addressing the ...

    Authors: Peter Bai James, Jon Wardle, Amie Steel, Jon Adams, Abdulai Jawo Bah and Stephen Sevalie

    Citation: BMC Complementary Medicine and Therapies 2020 20:137

    Content type: Research article

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  6. Type 2 diabetes mellitus is characterized by insulin resistance and pancreatic β-cell dysfunction. A decrease in β-cell mass, which occurs during the progression of Type 2 diabetes mellitus, contributes to imp...

    Authors: Patlada Suthamwong, Manabu Minami, Toshiaki Okada, Nonomi Shiwaku, Mai Uesugi, Masayuki Yokode and Kaeko Kamei

    Citation: BMC Complementary Medicine and Therapies 2020 20:136

    Content type: Research article

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  7. Human respiratory system infected with influenza A virus (IAV) elicited a robust pro-inflammatory response that resulted in severe illness and even death. Currently, limited immunomodulator is available to cou...

    Authors: Jiashun Li, Xiang Jie, Xiaoli Liang, Ziyu Chen, Peifang Xie, Xiping Pan, Beixian Zhou and Jing Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:135

    Content type: Research article

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  8. Piper chaba Hunt. is used as an ingredient in Thai traditional preparation for arthritis. Its isolated compound is piperine which shows anti-inflammatory activity. Piperine produces a burning sensation because it...

    Authors: Sumalee Panthong, Yasuyuki Imai, Takeshi Matsuoka, Wakana Suzuki, Tatsuo Watanabe, Yuko Terada, Kohta Kurohane, Kota Sekiguchi, Erina Ogawa, Yukina Endo and Arunporn Itharat

    Citation: BMC Complementary Medicine and Therapies 2020 20:134

    Content type: Research article

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  9. Sedum praealtum has been used for a long time in traditional medicine as an analgesic and anti-inflammatory agent. Its beneficial effects have been known since ancient times, when Latinos used it to treat sore an...

    Authors: Marcelo Fabiano Gomes Boriollo, Milene Bueno Marques, Thaísla Andrielle da Silva, Jeferson Júnior da Silva, Reigson Alves Dias, Thyago Henrique Neves Silva Filho, Isadora Letícia Ribeiro Melo, Carlos Tadeu dos Santos Dias, Wagner Luís de Carvalho Bernardo, Nelma de Mello Silva Oliveira, Vera Maria Peters, José Francisco Höfling and Denise Madalena Palomari Spolidorio

    Citation: BMC Complementary Medicine and Therapies 2020 20:133

    Content type: Research article

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  10. One of the most serious secondary manifestations of Cardiovascular Disease (CVD) is coronary atherosclerosis. This study aimed to evaluate whether aged garlic extract (AGE) can influence coronary artery calcif...

    Authors: Martiné Wlosinska, Ann-Christin Nilsson, Joanna Hlebowicz, Anders Hauggaard, Maria Kjellin, Mohammed Fakhro and Sandra Lindstedt

    Citation: BMC Complementary Medicine and Therapies 2020 20:132

    Content type: Research article

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  11. Paeoniae Radix Alba, the root of the plant Paeonia lactiflora Pall, is a common blood-enriching drug in traditional Chinese medicine. Its effectiveness in the clinical treatment of anaemia is remarkable, but its ...

    Authors: Xian-wen Ye, Ya-ling Deng, Lan-ting Xia, Hong-min Ren and Jin-lian Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:130

    Content type: Research article

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  12. Evolvulus alsinoides (Linn.) Linn. (Convolvulaceae) is a therapeutic herb alleviating brain patterns associated with three categories of regulatory principles of the body, mind, and behaviour. In the current rese...

    Authors: Pavithra Mettupalayam Kaliyannan Sundaramoorthy and Kannan Kilavan Packiam

    Citation: BMC Complementary Medicine and Therapies 2020 20:129

    Content type: Research article

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  13. Traditional medicine is broadly used across Asian societies for various medical conditions and health concerns. However, there remains a wide disparity between users and non-use, which makes it imperative to u...

    Authors: Benlu Xin, Siyu Mu, Teckkiang Tan, Anne Yeung, Danan Gu and Qiushi Feng

    Citation: BMC Complementary Medicine and Therapies 2020 20:128

    Content type: Research article

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  14. The popularity of fermented foods such as kefir, kuniss, and tofu has been greatly increasing over the past several decades, and the ability of probiotic bacteria to exert anticancer effects has recently becom...

    Authors: Nariman K. Badr El-Din, Sameh M. Shabana, Bashar A. Abdulmajeed and Mamdooh Ghoneum

    Citation: BMC Complementary Medicine and Therapies 2020 20:127

    Content type: Research article

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  15. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, ...

    Authors: Jinhong Leng, Xiaohua Li, He Tian, Chang Liu, Yining Guo, Su Zhang, Yang Chu, Jian Li, Ying Wang and Ling Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:126

    Content type: Research article

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  16. In Ethiopia, about 80% of the population use traditional medicine (TM) due to the cultural acceptability of healers and local pharmacopeias, the relatively low cost of traditional medicine, and the difficulty ...

    Authors: Fekensa Hailu, Amsale Cherie, Tigistu Gebreyohannis and Reta Hailu

    Citation: BMC Complementary Medicine and Therapies 2020 20:125

    Content type: Research article

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  17. Kaempferia parviflora (KP) has been used in traditional Thai medicine to cure gastrointestinal disorders since ancient times. Helicobacter pylori is an initiating factor in gastric pathogenesis via activation of ...

    Authors: Variya Nemidkanam, Yuko Kato, Tetsuo Kubota and Nuntaree Chaichanawongsaroj

    Citation: BMC Complementary Medicine and Therapies 2020 20:124

    Content type: Research article

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  18. Circaea mollis Sieb. & Zucc. has been used as a traditional herbal medicine in Hani Ethnopharmacy and possesses anti-arthritic activities. This study aimed to investigate the effect of Circaea mollis Siebold & Zu...

    Authors: Ji Hye Park, Yang Ju Son, Chang Ho Lee, Chu Won Nho and Gyhye Yoo

    Citation: BMC Complementary Medicine and Therapies 2020 20:123

    Content type: Research article

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  19. There is a long history of traditional/complementary medicine (T/CM) use by women during lactation. While it is important to evaluate such use within a scientific paradigm to ensure efficacy and safety, knowle...

    Authors: Tingyun Zheng, Weijie Chen, Hao Hu, Yitao Wang, Joanna E. Harnett and Carolina Oi Lam Ung

    Citation: BMC Complementary Medicine and Therapies 2020 20:122

    Content type: Research article

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  20. This study used a network pharmacology approach to elucidate the molecular mechanism governing the effect of Radix Achyranthis Bidentatae (RAB) on osteoarthritis (OA).

    Authors: Laigen Zhang, Xiaoqing Shi, Zhengquan Huang, Jun Mao, Wei Mei, Liang Ding, Li Zhang, Runlin Xing and Peimin Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:121

    Content type: Research article

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  21. Astragalin (AG), a flavonoid from many traditional herbs and medicinal plants, has been described to exhibit in vitro anti-inflammatory activity. The paper aimed to study the effects of astragalin on anti-inflamm...

    Authors: Xiuying Chen, Chang Cheng, Xuzheng Zuo and Wen Huang

    Citation: BMC Complementary Medicine and Therapies 2020 20:120

    Content type: Research article

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  22. Allergic rhinitis (AR) is a non-infectious immune disease and incidents of the disease has continuously increased in Thailand. Ginger, a Thai herb, is used in food and Thai traditional medicine. This study was...

    Authors: Rodsarin Yamprasert, Waipoj Chanvimalueng, Nichamon Mukkasombut and Arunporn Itharat

    Citation: BMC Complementary Medicine and Therapies 2020 20:119

    Content type: Research article

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  23. Lubiprostone (LBP) is a novel chloride channel opener that has been reported to activate chloride channel protein 2 (ClC-2) and cystic fibrosis transmembrane conductance regulator (CFTR). LBP facilitates fluid...

    Authors: Hiraku Akita, Susumu Yoshie, Takafumi Ishida, Yasuchika Takeishi and Akihiro Hazama

    Citation: BMC Complementary Medicine and Therapies 2020 20:118

    Content type: Research article

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  24. Our previous in vitro study reported that the ethyl acetate fraction (EAF) of Semen sojae germinatum (SSG), the processed sprout of Chinese black soybean, possessed the potent anti-inflammatory and chondroprotect...

    Authors: Jun Wang, Jie Guo, Shulan Li, Mengya Zhang and Bingshu He

    Citation: BMC Complementary Medicine and Therapies 2020 20:117

    Content type: Research article

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  25. Gestational diabetes mellitus (GDM) is one the most common complications of pregnancy. The present work aimed at investigating the effect of ginger on the blood glucose level of GDM women with impaired glucose...

    Authors: Fariba Hajimoosayi, Shahideh Jahanian Sadatmahalleh, Anoshirvan Kazemnejad and Reihane Pirjani

    Citation: BMC Complementary Medicine and Therapies 2020 20:116

    Content type: Research article

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  26. In the present study, the poncirin which is flavonoid-7-o-glycosides (isolated from the Poncirus trifoliata) in nature was evaluated against the Carbon tetra chloride (CCL4)-induced liver injury. The poncirin hav...

    Authors: Hadayat Ullah, Ashrafullah Khan, Muhammad Waleed Baig, Naseem Ullah, Naveed Ahmed, Muhammad Khalid Tipu, Hussain Ali and Salman Khan

    Citation: BMC Complementary Medicine and Therapies 2020 20:115

    Content type: Research article

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  27. Hancornia speciosa is usually used in Brazilian folk medicine to treat diabetes. The hypothesis of the present study is that this medicinal plant exerts beneficial effects on hyperglycemia, preventing diabetic co...

    Authors: Leila S. Neto, Rafaianne Q. Moraes-Souza, Thaigra S. Soares, Marcelo S. Pinheiro, Thaís Leal-Silva, Juliana C. Hoffmann, Madileine F. Américo, Kleber E. Campos, Débora C. Damasceno and Gustavo T. Volpato

    Citation: BMC Complementary Medicine and Therapies 2020 20:114

    Content type: Research article

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  28. Shenmai injection (SMI) has been used in the treatment of cardiovascular disease (CVD), such as heart failure, myocardial ischemia and coronary heart disease. It has been found to have efficacy on doxorubicin ...

    Authors: Lin Li, Dongli Yang, Jinghao Li, Lu Niu, Ye Chen, Xin Zhao, Patrick Kwabena Oduro, Chun Wei, Zongpei Xu, Qilong Wang and Yuhong Li

    Citation: BMC Complementary Medicine and Therapies 2020 20:112

    Content type: Research article

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  29. Many German general practitioners (GPs) use complementary and alternative medicine (CAM) in their daily work although most CAM procedures are controversial from an academic point of view.

    Authors: Agnes Ostermaier, Niklas Barth and Klaus Linde

    Citation: BMC Complementary Medicine and Therapies 2020 20:111

    Content type: Research article

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  30. Ovarian cancer is the leading cause of mortality among malignant gynecological tumors. Surgical resection and chemotherapy with intravenous platinum/taxanes drugs are the treatments of choice, with little effe...

    Authors: Luis Varela-Rodríguez, Blanca Sánchez-Ramírez, Verónica Ivonne Hernández-Ramírez, Hugo Varela-Rodríguez, Rodrigo Daniel Castellanos-Mijangos, Carmen González-Horta, Bibiana Chávez-Munguía and Patricia Talamás-Rohana

    Citation: BMC Complementary Medicine and Therapies 2020 20:110

    Content type: Research article

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  31. Ligularia fischeri (Ledeb) Turcz (LFT) is a well-known expectorant and active anti-inflammatory agent in Chinese traditional medicine. LFT’s expectorant effect is closely related to its anti-inflammatory effects....

    Authors: Xulong Huang, Yuan Gao, Feng Xu, Dongsheng Fan, Yuqing Liang, Xiangpei Wang and Hongmei Wu

    Citation: BMC Complementary Medicine and Therapies 2020 20:109

    Content type: Research article

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  32. While the use of complementary and alternative medicine (CAM) has become increasingly popular in western societies, we do not understand why CAM use is more frequent in some countries than in others. The aim o...

    Authors: Erlend L. Fjær, Erling R. Landet, Courtney L. McNamara and Terje A. Eikemo

    Citation: BMC Complementary Medicine and Therapies 2020 20:108

    Content type: Research article

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  33. The incidence of insulin resistance (IR) has rapidly increased worldwide over the last 20 years, no perfect solution has yet been identified. Finding new therapeutic drugs will help improve this situation. As ...

    Authors: Wen Gu, Min Yang, Qian Bi, Lin-Xi Zeng, Xi Wang, Jin-Cai Dong, Feng-Jiao Li, Xing-Xin Yang, Jing-Ping Li and Jie Yu

    Citation: BMC Complementary Medicine and Therapies 2020 20:107

    Content type: Research article

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  34. Combretum molle R.B/G. Don (Combretaceae) is a graceful deciduous shrub, distributed especially in tropical Africa and used in traditional medicine in the treatment of malaria, diabetes, and bacterial, liver and ...

    Authors: David Miaffo, Sylvie Léa Wansi, Fidèle Ntchapda and Albert Kamanyi

    Citation: BMC Complementary Medicine and Therapies 2020 20:106

    Content type: Research article

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  35. Cissus quadrangularis Linn. (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients in CQ. It is still unclear which compounds are the active i...

    Authors: Jetsada Ruangsuriya, Suporn Charumanee, Supat Jiranusornkul, Panee Sirisa-ard, Busaban Sirithunyalug, Jakkapan Sirithunyalug, Thanawat Pattananandecha and Chalermpong Saenjum

    Citation: BMC Complementary Medicine and Therapies 2020 20:105

    Content type: Research article

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  36. Peri-implant inflammation resulting from the presence of Candida biofilms may compromise the longevity of implant-supported dentures. This study evaluated the inhibitory effect of Brazilian red propolis on mono-s...

    Authors: Loyse Martorano-Fernandes, Yuri Wanderley Cavalcanti and Leopoldina de Fátima Dantas de Almeida

    Citation: BMC Complementary Medicine and Therapies 2020 20:104

    Content type: Research article

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  37. Lamiaceae family is one of the most diverse and common plant families in terms of ethnomedicine due to their potential therapeutic effects. The aim of this study is to investigate the correlation between the c...

    Authors: Sarra Moumni, Ameur Elaissi, Amine Trabelsi, Abderrahmen Merghni, Imed Chraief, Brahim Jelassi, Rachid Chemli and Salima Ferchichi

    Citation: BMC Complementary Medicine and Therapies 2020 20:103

    Content type: Research article

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  38. Panch phoron is a mixture of five spices containing an equal proportion of Foeniculum vulgare (fennel), Trigonella foenum-graecum Linn (fenugreek), Nigella sativa (black cumin), Cuminum cyminum (cumin) and Brassi...

    Authors: Zarin Tasnim Gias, Fatima Afsana, Polak Debnath, M. Shadidul Alam, Tania Naz Ena, Md Hemayet Hossain, Preeti Jain and Hasan Mahmud Reza

    Citation: BMC Complementary Medicine and Therapies 2020 20:102

    Content type: Research article

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  39. Particulate matter (PM) can cause various negative acute and chronic diseases of the respiratory system, including the upper airways. Curcumin has been reported to have anti-inflammatory and anti-oxidative eff...

    Authors: Ji-Sun Kim, Jeong-Min Oh, Hyunsu Choi, Sung Won Kim, Soo Whan Kim, Byung Guk Kim, Jin Hee Cho, Joohyung Lee and Dong Chang Lee

    Citation: BMC Complementary Medicine and Therapies 2020 20:101

    Content type: Research article

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  40. Few studies have evaluated the association between the risk of coronary artery disease (CAD) and the use of Chinese herbal products (CHP) in patients with rheumatoid arthritis (RA). This study investigated the...

    Authors: Han-Hua Yu, Nai-Huan Hsiung, Jen-Huai Chiang and Hsuan-Shu Shen

    Citation: BMC Complementary Medicine and Therapies 2020 20:100

    Content type: Research article

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  41. Staphylococcus aureus is the most dominant human pathogen, responsible for a variety of chronic and severe infections. There is mounting evidence that persisters are associated with treatment failure and relapse ...

    Authors: Shuzhen Xiao, Peng Cui, Wanliang Shi and Ying Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:99

    Content type: Research article

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  42. The Rumex acetosa has been used in medicinal treatment, food technology and phytotherapeutics in Eastern Asia and many other countries. However, its effect on cardiovascular system and antiplatelet activity remai...

    Authors: Dahye Jeong, Muhammad Irfan, Dong-Ha Lee, Seung-Bok Hong, Jae-Wook Oh and Man Hee Rhee

    Citation: BMC Complementary Medicine and Therapies 2020 20:98

    Content type: Research article

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  43. Frankincense and myrrh are used as traditional anti-inflammatory and analgesic medicines in China. It has been reported that frankincense and myrrh have significant anti-tumor activities. The present study was...

    Authors: Rumeng Gao, Xiaodong Miao, Chengjing Sun, Shulan Su, Yue Zhu, Dawei Qian, Zhen Ouyang and Jinao Duan

    Citation: BMC Complementary Medicine and Therapies 2020 20:96

    Content type: Research article

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  44. Ovarian cancer therapy generally involves systemic chemotherapy with anticancer drugs; however, chemotherapy with a platinum-based drug has often been shown to cause adverse reactions and drug resistance in ov...

    Authors: Jae Ryul Bae, Wook Ha Park, Dong Hoon Suh, Jae Hong No, Yong Beom Kim and Kidong Kim

    Citation: BMC Complementary Medicine and Therapies 2020 20:94

    Content type: Research article

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  45. Previous research has revealed high rates of traditional medicine usage in Nigeria. Reports of widespread contamination of herbal medicine products and higher rates of noncompliance with Western medications am...

    Authors: Suellen Li, Stella Odedina, Imaria Agwai, Oladosu Ojengbede, Dezheng Huo and Olufunmilayo I. Olopade

    Citation: BMC Complementary Medicine and Therapies 2020 20:93

    Content type: Research article

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  46. Acinetobacter baumannii is an opportunistic pathogen that causes nosocomial infections especially in patients in intensive care units (ICUs). Accordingly, the aim of our study was to detection of adeABC efllux pu...

    Authors: Hassan Mahmoudi, Leili Shokoohizadeh, Nayreh Zare Fahim, Ali Mohamadi Bardebari, Shirin Moradkhani and Mohammad Yousef Alikhani

    Citation: BMC Complementary Medicine and Therapies 2020 20:92

    Content type: Research article

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