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  1. With the current concern caused by drug resistant microorganisms, alternatives to traditional antimicrobials are increasingly necessary. Historical holistic treatments involving natural approaches are now of i...

    Authors: Rhegan C. McGregor, Kory A. Parker, Jacob M. Hornby and Leigh C. Latta IV

    Citation: BMC Complementary and Alternative Medicine 2019 19:247

    Content type: Research article

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  3. Catalpol, a natural iridoid glycoside in Rehmannia glutinosa, can alleviate proteinuria associated with diabetic nephropathy (DN), however, whether catalpol has a protective effect against podocyte injury in DN r...

    Authors: Yan Chen, Qingpu Liu, Zengfu Shan, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng and Weisheng Feng

    Citation: BMC Complementary and Alternative Medicine 2019 19:244

    Content type: Research article

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  4. Cyanidin-3-rutinoside (C3R), a naturally occurring anthocyanin, possesses anti-oxidant, anti-hyperglycemic, anti-glycation and cardioprotective properties. However, its mechanisms responsible for anti-hyperlip...

    Authors: Thavaree Thilavech and Sirichai Adisakwattana

    Citation: BMC Complementary and Alternative Medicine 2019 19:242

    Content type: Research article

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  5. Mulberry silkworm larvae (Bombyx mori) are known as the oldest resource of food and traditional medicine. Although silkworm larvae have been reported to treat various chronic diseases, the effect of fermentation ...

    Authors: Hyun-Dong Cho, Hye-Ji Min, Yeong-Seon Won, Hee-Young Ahn, Young-Su Cho and Kwon-Il Seo

    Citation: BMC Complementary and Alternative Medicine 2019 19:241

    Content type: Research article

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  6. Major depression is an important complication in patients with breast cancer, but is an underrecognized and undertreated condition in this population. The Baihe Zhimu Tang (BZ formula) is a traditional Chinese...

    Authors: Hailong Li, Chunyu Wu, Yu Liu, Shuo Zhang and Xiufei Gao

    Citation: BMC Complementary and Alternative Medicine 2019 19:240

    Content type: Research article

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  7. Chronic obstructive pulmonary disease (COPD) is one global disease. Lung function gradually declines. Medication does not fully reverse the airflow limitation. Qigong’s role in COPD rehabilitation has been ass...

    Authors: Hongxuan Tong, Yihua Liu, Yutian Zhu, Boli Zhang and Jingqing Hu

    Citation: BMC Complementary and Alternative Medicine 2019 19:239

    Content type: Research article

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  8. Annonacin, an annonaceous acetogenin isolated from Annona muricata has been reported to be strongly cytotoxic against various cell lines, in vitro. Nevertheless, its effect against in vivo tumor promoting activit...

    Authors: Mohd Rohaizad Md Roduan, Roslida Abd Hamid and Norhafizah Mohtarrudin

    Citation: BMC Complementary and Alternative Medicine 2019 19:238

    Content type: Research article

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  9. Rice husk, a waste material produced during milling, contains numerous phytochemicals that may be sources of cancer chemopreventive agents. Various biological activities of white and colored rice husk have bee...

    Authors: Arpamas Chariyakornkul, Charatda Punvittayagul, Sirinya Taya and Rawiwan Wongpoomchai

    Citation: BMC Complementary and Alternative Medicine 2019 19:237

    Content type: Research article

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  10. Syzygium cumini (L.) Skeels. is one of the very popular traditionally used medicinal plants with numerous pharmacological activities including antioxidant, hypoglycemic and anti-inflammatory. However, actions of

    Authors: Ahad Abdul Rehman, Azra Riaz, Muhammad Arif Asghar, Muhammad Liaquat Raza, Shadab Ahmed and Kamran Khan

    Citation: BMC Complementary and Alternative Medicine 2019 19:236

    Content type: Research article

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  11. Oxyresveratrol is a major bioactive component derived from the heartwood of Artocarpus lacucha. This compound exerts several biological activities, including neuroprotective effects in vitro and in vivo. However,...

    Authors: Dhirarin Junsaeng, Tosapol Anukunwithaya, Phanit Songvut, Boonchoo Sritularak, Kittisak Likhitwitayawuid and Phisit Khemawoot

    Citation: BMC Complementary and Alternative Medicine 2019 19:235

    Content type: Research article

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  12. The neurobiology of persistent pain shares common underlying psychobiology with that of traumatic stress. Modern treatments for traumatic stress often involve bottom-up sensorimotor retraining/exposure therapi...

    Authors: Alison Flehr, Christopher Barton, Jan Coles, Stephen J. Gibson, Gavin W. Lambert, Elisabeth A. Lambert, Arup K. Dhar and John B. Dixon

    Citation: BMC Complementary and Alternative Medicine 2019 19:234

    Content type: Research article

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  13. Resveratrol is reported to inhibit the growth of prostate, which is characteristic of benign prostatic hyperplasia (BPH) condition. However, the mechanism remains unclear. This study aimed to identify the effe...

    Authors: Chao Li, Wan-Li Hu, Meng-Xin Lu and Guan-Fa Xiao

    Citation: BMC Complementary and Alternative Medicine 2019 19:233

    Content type: Research article

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  14. Metabolic syndrome is a non-communicable disease inclusive of risk factors such as central obesity, hypertension, hyperglycaemia and dyslipidaemia. In this present study, we investigated the ability of Pandanus a...

    Authors: Nur Hidayah Reshidan, Suhaila Abd Muid and Norshalizah Mamikutty

    Citation: BMC Complementary and Alternative Medicine 2019 19:232

    Content type: Research article

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  15. In Korea and China, asiasari radix (AR) is widely used as a traditional anti-inflammatory and analgesic agent. After its skin-regenerating and hair loss-preventing activities were identified, several types of ...

    Authors: Kwang-Ha Park, Jeong-Hae Choi, Yeon-Suk Song, Gyoo-Cheon Kim and Jin-Woo Hong

    Citation: BMC Complementary and Alternative Medicine 2019 19:231

    Content type: Research article

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  16. Hyperglycemia and dyslipidemia are classic features of patients with diabetes mellitus (DM). Cordyceps taii, a folk medicinal fungus native to southern China, possesses various pharmacological activities. This st...

    Authors: Ru-Ming Liu, Rong Dai, Yi Luo and Jian-Hui Xiao

    Citation: BMC Complementary and Alternative Medicine 2019 19:230

    Content type: Research article

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  17. Use of complementary and alternative medicine (CAM), including vitamins, minerals, herbals, and other dietary supplements, is widespread in the United States (ranging from 24% in Hispanics to 50% in American I...

    Authors: Srujitha Marupuru, David Rhys Axon and Marion K. Slack

    Citation: BMC Complementary and Alternative Medicine 2019 19:229

    Content type: Research article

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  18. Non-alcoholic fatty liver disease (NAFLD) may increase the sensitivity to liver injury caused by stimulants such as drugs and poisons. The traditional Chinese medicine (TCM) Jiang-Zhi Granule (JZG) has been prove...

    Authors: Lili Yang, Yan Zhou, Haiyan Song and Peiyong Zheng

    Citation: BMC Complementary and Alternative Medicine 2019 19:228

    Content type: Research article

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  19. Oxidative stress is an imbalance between the levels of reactive oxygen species (ROS), reactive nitrogen species (RNS) and endogenous antioxidants. The aetiology and pathogenesis of several oral diseases are at...

    Authors: Ignacio Peralta, Carla Marrassini, María Laura Barreiro Arcos, Graciela Cremaschi, María Rosario Alonso and Claudia Anesini

    Citation: BMC Complementary and Alternative Medicine 2019 19:227

    Content type: Research article

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  20. Six Chinese herb formulas, namely, the Weijing decoction (WJ), the Maxingshigan decoction (MXSG), the Yuebijiabanxia decoction (YBBX), the Qingqihuatan decoction (QQHT), the Dingchuan decoction (DC) and the Sa...

    Authors: Shaonan Liu, Jing Chen, Jinhong Zuo, Jiaqi Lai, Lei Wu and Xinfeng Guo

    Citation: BMC Complementary and Alternative Medicine 2019 19:226

    Content type: Research article

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  21. We aimed to evaluate the global scientific output of research of acupuncture on insomnia and explore the hotspots and frontiers from 1999 to 2018, by using bibliometric methods.

    Authors: Wenya Pei, Rui Peng, Yuan Gu, Xiaohong Zhou and Jingwen Ruan

    Citation: BMC Complementary and Alternative Medicine 2019 19:225

    Content type: Research article

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  22. Commercial herbal medicines (CHMs) marketed as immune boosters are gaining wide popularity in South Africa, in the absence of control and regulatory guidelines. These commercially packaged and labelled herbal ...

    Authors: Mmamosheledi E. Mothibe, Christina P. Kahler-Venter and Elzbieta Osuch

    Citation: BMC Complementary and Alternative Medicine 2019 19:224

    Content type: Research article

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  23. We aimed to compare patients’ and physicians’ safety reporting using data from large acupuncture trials (44,818 patients) and to determine associations between patient characteristics and reporting of adverse ...

    Authors: Thea Schwaneberg, Claudia M. Witt, Stephanie Roll and Daniel Pach

    Citation: BMC Complementary and Alternative Medicine 2019 19:223

    Content type: Research article

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  24. Chronic hepatic diseases are serious problems worldwide, which may lead to the development of fibrosis and eventually cirrhosis. Despite the significant number of people affected by hepatic fibrosis, no effect...

    Authors: Caio Mateus da Silva, Flávio Henrique Caetano, Franco Dani Campos Pereira, Maria Aparecida Marin Morales, Kumiko Koibuchi Sakane and Karen C. M. Moraes

    Citation: BMC Complementary and Alternative Medicine 2019 19:222

    Content type: Research article

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  25. Lichens produce a huge diversity of bioactive compounds with several biological effects. Gyrophoric acid (GA) is found in high concentrations in the common lichen Umbilicaria hirsuta, however evidence for biologi...

    Authors: Michal Goga, Martin Kello, Maria Vilkova, Klaudia Petrova, Martin Backor, Wolfram Adlassnig and Ingeborg Lang

    Citation: BMC Complementary and Alternative Medicine 2019 19:221

    Content type: Research article

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  26. Baeckea frutescens (B. frutescens) of the family Myrtaceae is a plant that has been used in traditional medicine. It is known to have antibacterial, antipyretic and cytoprotective properties. The objective of thi...

    Authors: S. H. Shahruzaman, M. F. Mustafa, S. Ramli, S. Maniam, S. Fakurazi and S. Maniam

    Citation: BMC Complementary and Alternative Medicine 2019 19:220

    Content type: Research article

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  27. Methicillin-resistant Staphylococcus aureus (MRSA) causes serious infections in hospitals. Penthorum chinense Pursh (PCP), employed by the Miao ethnic minority in China, presents antibacterial activities. In this...

    Authors: Bin Ding, Qinchao Ding, Shun Zhang, Zhuo Jin, Zhaolei Wang, Songtao Li and Xiaobing Dou

    Citation: BMC Complementary and Alternative Medicine 2019 19:219

    Content type: Research article

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  28. Staphylococcal aureus (S. aureus) has become the leading causative pathogen of Prosthetic Joint Infection (PJI), which is the most devastating complication after arthroplasty surgeries. Due to the biofilm formati...

    Authors: Jiaqi Tan, Jin Wang, Chuang Yang, Chongzun Zhu, Geyong Guo, Jin Tang and Hao Shen

    Citation: BMC Complementary and Alternative Medicine 2019 19:218

    Content type: Research article

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  29. Systemic inflammation driven neuroinflammation is an event which correlates with pathogenesis of several neurodegenerative diseases. Therefore, targeting peripheral and central inflammation simultaneously coul...

    Authors: Muskan Gupta and Gurcharan Kaur

    Citation: BMC Complementary and Alternative Medicine 2019 19:217

    Content type: Research article

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  30. Breast cancer is still the most common malignant tumor that threatens the female’s life in the world, especially triple-negative breast cancer (TNBC), one of the most difficult subtypes. Lack of targeted thera...

    Authors: Mingjiang Yao, Xiaodi Fan, Bo Yuan, Norio Takagi, Sai Liu, Xiao Han, Junguo Ren and Jianxun Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:216

    Content type: Research article

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  31. Mounting evidence indicates that the cerebral cortex is an important physiological system of emotional activity, and its dysfunction may be the main cause of stress. Glutamate is the primary excitatory neurotr...

    Authors: Yan Liu, Xiu-fang Ding, Xin-xing Wang, Xiao-juan Zou, Xiao-juan Li, Yue-yun Liu, Jie Li, Xiu-yun Qian and Jia-xu Chen

    Citation: BMC Complementary and Alternative Medicine 2019 19:215

    Content type: Research article

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  32. The present study evaluated the antinociceptive effect of the bark of Artocarpus lacucha, which is used for the treatment of stomachache, headache and boils in the traditional system of medicine.

    Authors: Shanta Islam, Md. Shafiullah Shajib, Ridwan Bin Rashid, Mohammad Firoz Khan, Md. Abdullah Al-Mansur, Bidyut Kanti Datta and Mohammad Abdur Rashid

    Citation: BMC Complementary and Alternative Medicine 2019 19:214

    Content type: Research article

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  33. Various extracts of Centella asiatica (Apiaceae) and its active constituent, asiaticoside, have been reported to possess wound healing property when assessed using various in vivo and in vitro models. In an attem...

    Authors: Afnan Sh. Ahmed, Muhammad Taher, Uttam Kumar Mandal, Juliana Md Jaffri, Deny Susanti, Syed Mahmood and Zainul Amiruddin Zakaria

    Citation: BMC Complementary and Alternative Medicine 2019 19:213

    Content type: Research article

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  34. Recently, there has been an increasing tendency to go back to nature in search of new medicines. To facilitate this, a great deal of effort has been made to compile information on natural products worldwide, a...

    Authors: Lemessa Etana Bultum, Assefa Mussa Woyessa and Doheon Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:212

    Content type: Database

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  35. Breast cancer is the leading cause of cancer-related death in women worldwide. Although traditional Chinese medicine (TCM) is commonly used by patients with breast cancer, little is known about TCM prescriptio...

    Authors: Yu-Te Liu, Chao-Hsiang Hsiao, Bor-Show Tzang and Tsai-Ching Hsu

    Citation: BMC Complementary and Alternative Medicine 2019 19:211

    Content type: Research article

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  36. Skin diseases are a major health concern especially in association with human immune deficiency syndrome and acquired an immune deficiency. The aim of this study was to document the ethnomedicinal information ...

    Authors: Khafsa Malik, Mushtaq Ahmad, Muhammad Zafar, Riaz Ullah, Hafiz Majid Mahmood, Bushra Parveen, Neelam Rashid, Shazia Sultana, Syed Nasar Shah and Lubna

    Citation: BMC Complementary and Alternative Medicine 2019 19:210

    Content type: Research article

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  37. The imbalance between the generation of free radicals and natural cellular antioxidant defenses, known as oxidative stress, can cause oxidation of biomolecules and further contribute to aging-associated diseas...

    Authors: Palika Wetchakul, Jo Aan Goon, Ademola Ezekiel Adekoya, Opeyemi Joshua Olatunji, Sutticha Ruangchuay, Patcharawalai Jaisamut, Acharaporn Issuriya, Nongluk Kunworarath, Surasak Limsuwan and Sasitorn Chusri

    Citation: BMC Complementary and Alternative Medicine 2019 19:209

    Content type: Research article

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  38. Acupuncture is widely used worldwide, and systematic reviews on acupuncture are increasingly being published. Although acupuncture systematic reviews share several essential elements with other systematic revi...

    Authors: Xiaoqin Wang, Yaolong Chen, Yali Liu, Liang Yao, Janne Estill, Zhaoxiang Bian, Taixiang Wu, Hongcai Shang, Myeong Soo Lee, Dang Wei, Jinhui Tian, Bin Ma, Yongfeng Wang, Guihua Tian and Kehu Yang

    Citation: BMC Complementary and Alternative Medicine 2019 19:208

    Content type: Research article

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  39. Cnidii Rhizoma is the dried root stem of Cnidium officinale Makino. Cnidii Rhizoma (CR) has been used to treat menstrual irregularity, menstrual pain, and menopause in Korea. However, the effects and mechanisms o...

    Authors: Ka-Yeon Lee, Jae-Hyun Kim, Eun-Young Kim, Mijung Yeom, Hyuk-Sang Jung and Youngjoo Sohn

    Citation: BMC Complementary and Alternative Medicine 2019 19:207

    Content type: Research article

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  40. About 425 million adults had diabetes mellitus globally in 2017. Type 2 diabetes accounts for the enormous majority of diabetes cases and it is gradually growing which is predicted to increase by 48% in 2045. ...

    Authors: Gebretsadkan Hintsa Tekulu, Ephrem Mebrahtu Araya and Hayelom Gebrekirstos Mengesha

    Citation: BMC Complementary and Alternative Medicine 2019 19:206

    Content type: Research article

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  41. Gastric ulcer is one of the most prevalent diseases worldwide. In Iranian folk medicine, Achillea wilhelmsii (AW) is used as a treatment for gastric ulcer. Previous reports also mentioned Antiulcerogenic properti...

    Authors: Mehdi Koushki, Reyhaneh Farrokhi Yekta, Nasrin Amiri-Dashatan, Masoumeh Dadpay and Fatemeh Goshadrou

    Citation: BMC Complementary and Alternative Medicine 2019 19:205

    Content type: Research article

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  42. Metastasis is the main cause of lung cancer death. As a seed of metastasis, circulating tumor cells are an important target for metastasis intervention. The traditional Chinese medicine, Jinfukang, has been cl...

    Authors: Zujun Que, Zhiyi Zhou, Bin Luo, Changsheng Dong, Yi Jiang, Hegen Li and Jianhui Tian

    Citation: BMC Complementary and Alternative Medicine 2019 19:204

    Content type: Research article

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  43. 5-Florouracil (5-FU) is a commonly used chemotherapeutic drug for cholangiocarcinoma, whereas it has unsatisfactory effect, and patients often have chemo-resistance to it. The combination of chemotherapeutic a...

    Authors: Zhaoyu Fu, Kexin Ma, Bing Dong, Chongyu Zhao, Chi Che, Chengyong Dong, Rixin Zhang, Haibo Wang, Xiang Wang and Rui Liang

    Citation: BMC Complementary and Alternative Medicine 2019 19:203

    Content type: Research article

    Published on:

  44. Scientific studies have shown that the potential therapeutic efficacy of curcumin in several diseases is due to its potent antioxidant and anti-inflammatory properties. Consequently, curcumin supplementation s...

    Authors: Tatiane Andreza Lima Silva, Danielle Coutinho Medeiros, Gidyenne Christine Bandeira Silva Medeiros, Rafaela Catherine Silva Cunha Medeiros, Juliany de Souza Araújo, Jason Azevedo Medeiros, Marcela Abbott Galvao Ururahy, Ronaldo Vagner Thomatieli Santos, Radames Maciel Vitor Medeiros, Lucia Leite-Lais and Paulo Moreira Silva Dantas

    Citation: BMC Complementary and Alternative Medicine 2019 19:202

    Content type: Research article

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  45. Self-directed learning is a student-centered approach based on the students’ evaluation about their own learning needs. Self-directed practice is a component of the self-directed learning which focus on achiev...

    Authors: Giandomenico D’Alessandro, Giacomo Consorti and Francesco Cerritelli

    Citation: BMC Complementary and Alternative Medicine 2019 19:201

    Content type: Research article

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  46. Astilbe rivularis L. is an indigenous medicinal plant growing in high altitude of Darjeeling Himalayan region of India and Nepal. The plant rhizome has been used traditionally as medicine by local tribes to treat...

    Authors: Vijeta Rai, Anoop Kumar, Vaskar Das and Shilpi Ghosh

    Citation: BMC Complementary and Alternative Medicine 2019 19:200

    Content type: Research article

    Published on:

  47. Triphala is an indigenous medical product used for a variety of diseases. This study was conducted to determine the effect of Triphala on antibiotic properties of gentamicin and oxacillin against multi-drug re...

    Authors: Amirthasingam Manoraj, Vasanthi Thevanesam, B. M. R. Bandara, Asela Ekanayake and Veranja Liyanapathirana

    Citation: BMC Complementary and Alternative Medicine 2019 19:199

    Content type: Research article

    Published on:

  48. Endothelial cell inflammation is a central event in the pathogenesis of numerous cardiovascular diseases, including sepsis and atherosclerosis. Triptolide, a principal bioactive ingredient of Traditional Chine...

    Authors: Chundong Song, Youping Wang, Lin Cui, Fengna Yan and Si Shen

    Citation: BMC Complementary and Alternative Medicine 2019 19:198

    Content type: Research article

    Published on:

  49. The present study was aimed to evaluate the molecular level anticaries effect of different medicinal plants against Streptococcus mutans (S.mutans) glucosyltransferases (gtf).

    Authors: Kiranmai Mandava, Uma Rajeswari Batchu, Shravya Kakulavaram, Shulamithi Repally, Ishwarya Chennuri, Srinivas Bedarakota and Namratha Sunkara

    Citation: BMC Complementary and Alternative Medicine 2019 19:197

    Content type: Research article

    Published on:

  50. The rise in use of food supplements based on botanical ingredients (herbal supplements) is depicted as part of a trend empowering consumers to manage their day-to-day health needs, which presupposes access to ...

    Authors: Matthew Peacock, Mihaela Badea, Flavia Bruno, Lada Timotijevic, Martina Laccisaglia, Charo Hodgkins, Monique Raats and Bernadette Egan

    Citation: BMC Complementary and Alternative Medicine 2019 19:196

    Content type: Research article

    Published on:

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