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  1. Hawthorn extract has been used for cardiovascular diseases for centuries. Recent trials have demonstrated its efficacy for the treatment of heart failure, and the results of several small trials suggest it may...

    Authors: Gary N Asher, Anthony J Viera, Mark A Weaver, Rosalie Dominik, Melissa Caughey and Alan L Hinderliter
    Citation: BMC Complementary and Alternative Medicine 2012 12:26
    Content type: Research article Published on:

  2. A standardized poly-herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes used traditionally in Sri Lanka for cancer therapy has been demonstrated previously, to have anti-...

    Authors: Sameera R Samarakoon, Ira Thabrew, Prasanna B Galhena and Kamani H Tennekoon
    Citation: BMC Complementary and Alternative Medicine 2012 12:25
    Content type: Research article Published on:

  3. This study was conducted to evaluate the efficacy of the herbal formula PM012 on an Alzheimer's disease model, human presenilin 2 mutant transgenic mice (hPS2m), and also to evaluate the toxicity of PM012 in S...

    Authors: Sung-Hwa Sohn, Soo-Jeong Kim, Yong Kim, Insop Shim and Hyunsu Bae
    Citation: BMC Complementary and Alternative Medicine 2012 12:24
    Content type: Research article Published on:

  4. Chemotherapy of cholangiocarcinoma (CCA), a devastating cancer with increasing worldwide incidence and mortality rates, is largely ineffective. The discovery and development of effective chemotherapeutics is u...

    Authors: Tullayakorn Plengsuriyakarn, Vithoon Viyanant, Veerachai Eursitthichai, Porntipa Picha, Piengchai Kupradinun, Arunporn Itharat and Kesara Na-Bangchang
    Citation: BMC Complementary and Alternative Medicine 2012 12:23
    Content type: Research article Published on:

  5. Curcumin is a principal compound of turmeric, commonly used to treat tumors and other diseases. However, its anti-cancer activity in human acute monocytic leukemia THP-1 cells is not clear. This study aimed to...

    Authors: Chu-Wen Yang, Chi-Lun Chang, Hsin-Chen Lee, Chin-Wen Chi, Jia-Ping Pan and Wen-Chin Yang
    Citation: BMC Complementary and Alternative Medicine 2012 12:22
    Content type: Research article Published on:

  6. Daming capsule (DMC), a traditional Chinese formula, has a lipid-modulating action with reduced adverse side effects as compared with other lipid lowering compounds. Since endothelial dysfunction often accompa...

    Authors: Rong Zhang, Huifang Niu, Ning Wang, Lihua Sun, Yi Xu, Ruibo Zhao, Xiang Ban, Yao Yu, Baofeng Yang and Jing Ai
    Citation: BMC Complementary and Alternative Medicine 2012 12:21
    Content type: Research article Published on:

  8. Obesity is an urgent public health problem, yet only a few clinical trials have systematically tested the efficacy of long-term weight-loss maintenance interventions. This randomized clinical trial tested the ...

    Authors: Charles R Elder, Christina M Gullion, Lynn L DeBar, Kristine L Funk, Nangel M Lindberg, Cheryl Ritenbaugh, Gayle Meltesen, Cherri Gallison and Victor J Stevens
    Citation: BMC Complementary and Alternative Medicine 2012 12:19
    Content type: Research article Published on:

  9. To-date modern drug research has focused on the discovery and synthesis of single active substances. However, multicomponent preparations are gaining increasing importance in the phytopharmaceutical field by d...

    Authors: Johanna M Gostner, Oliver A Wrulich, Marcel Jenny, Dietmar Fuchs and Florian Ueberall
    Citation: BMC Complementary and Alternative Medicine 2012 12:18
    Content type: Debate Published on:

  10. Oyaksungisan (OY) has been used as a traditional drug in east-Asian countries. However, its effect on inflammation still remains unknown. In this study, to provide insight into the biological effects of OY and...

    Authors: You-Chang Oh, Won-Kyung Cho, Jin Hui Oh, Ga Young Im, Yun Hee Jeong, Min Cheol Yang and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2012 12:17
    Content type: Research article Published on:

  11. Fumaria parviflora Linn. (Fumariaceae), is a small branched annual herb found in many parts of the world including Saudi Arabia and Pakistan. This study was designed to provide pharmacological basis for the medi...

    Authors: Najeeb-ur-Rehman, Malik Hassan Mehmood, Adnan J Al-Rehaily, Ramzi AA Mothana and Anwar H Gilani
    Citation: BMC Complementary and Alternative Medicine 2012 12:16
    Content type: Research article Published on:

  12. Bryophyllum pinnata (B. pinnata) is a common medicinal plant used in traditional medicine of India and of other countries for curing various infections, bowel diseases, healing wounds and other ailments. However...

    Authors: Sutapa Mahata, Saurabh Maru, Shirish Shukla, Arvind Pandey, G Mugesh, Bhudev C Das and Alok C Bharti
    Citation: BMC Complementary and Alternative Medicine 2012 12:15
    Content type: Research article Published on:

  13. Constipation is a very common health problem in the world. Intake of sufficient amount of dietary fibers is a cornerstone in the prevention and treatment of constipation. As a traditional medicine, flaxseed ha...

    Authors: Jiqu Xu, Xiaoqi Zhou, Chang Chen, Qianchun Deng, Qingde Huang, Jin'e Yang, Nianhong Yang and Fenghong Huang
    Citation: BMC Complementary and Alternative Medicine 2012 12:14
    Content type: Research article Published on:

  14. Costus speciosus (Koen ex.Retz.) Sm (Costaceae) is an Indian ornamental plant which has long been used medicinally in traditional systems of medicine. The plant has been found to possess diverse pharmacological ...

    Authors: Veeramuthu Duraipandiyan, Naif Abdullah Al-Harbi, Savarimuthu Ignacimuthu and Chinnasamy Muthukumar
    Citation: BMC Complementary and Alternative Medicine 2012 12:13
    Content type: Research article Published on:

  16. Tobacco smoking is still a worldwide health risk. Current pharmacotherapies have at best, a success rate of no more than 50%. Auricular (ear) acupressure has been purported to be beneficial in achieving smokin...

    Authors: Lawrence Leung, Troy Neufeld and Scott Marin
    Citation: BMC Complementary and Alternative Medicine 2012 12:11
    Content type: Study protocol Published on:

  17. Standardized Korean red ginseng extract has become the best-selling influenza-like illness (ILI) remedy in Korea, yet much controversy regarding the efficacy of the Korean red ginseng (KRG) in reducing ILI inc...

    Authors: Ki-Chan Ha, Min-Gul Kim, Mi-Ra Oh, Eun-Kyung Choi, Hyang-Im Back, Sun-Young Kim, Eun-Ok Park, Dae-Young Kwon, Hye-Jeong Yang, Min-Jeong Kim, Hee-Joo Kang, Ju-Hyung Lee, Kyung-Min Choi, Soo-Wan Chae and Chang-Seop Lee
    Citation: BMC Complementary and Alternative Medicine 2012 12:10
    Content type: Study protocol Published on:

  18. Dipteryx alata Vogel popularly known as "baru" is an important commercial leguminous tree species from the Brazilian Cerrado, which possess medicinal properties, besides its fruits consumption by animals and hum...

    Authors: Natália Mencacci Esteves-Pedro, Thaisa Borim, Virginia Sbrugnera Nazato, Magali Glauzer Silva, Patricia Santos Lopes, Márcio Galdino dos Santos, Cháriston André Dal Belo, Cássia Regina Primila Cardoso, Eliana Aparecida Varanda, Francisco Carlos Groppo, Marli Gerenutti and Yoko Oshima-Franco
    Citation: BMC Complementary and Alternative Medicine 2012 12:9
    Content type: Research article Published on:

  19. Arctium lappa L. root has traditionally been recommended as an aphrodisiac agent. It is used to treat impotence and sterility in China, and Native Americans included the root in herbal preparations for women in ...

    Authors: Cao JianFeng, Zhang PengYing, Xu ChengWei, Huang TaoTao, Bai YunGui and Chen KaoShan
    Citation: BMC Complementary and Alternative Medicine 2012 12:8
    Content type: Research article Published on:

  20. Tai Chi (TC) is a mind-body exercise that shows potential as an effective and safe intervention for preventing fall-related fractures in the elderly. Few randomized trials have simultaneously evaluated TC's po...

    Authors: Peter M Wayne, Douglas P Kiel, Julie E Buring, Ellen M Connors, Paolo Bonato, Gloria Y Yeh, Calvin J Cohen, Chiara Mancinelli and Roger B Davis
    Citation: BMC Complementary and Alternative Medicine 2012 12:7
    Content type: Research article Published on:

  21. Oral candidiasis is a common fungal disease mainly caused by Candida albicans. The aim of this study was to investigate the effects of A-type cranberry proanthocyanidins (AC-PACs) on pathogenic properties of C. a...

    Authors: Mark Feldman, Shinichi Tanabe, Amy Howell and Daniel Grenier
    Citation: BMC Complementary and Alternative Medicine 2012 12:6
    Content type: Research article Published on:

  22. Tanshinone IIA (Tan IIA) is a diterpene quinone extracted from the root of Salvia miltiorrhiza, a Chinese traditional herb. Although previous studies have reported the anti-tumor effects of Tan IIA on various hum...

    Authors: Chang Liu, Jianqin Li, Liangjie Wang, Fuqun Wu, Linfang Huang, Yue Xu, Jieyu Ye, Bin Xiao, Fanyi Meng, Shilin Chen and Mo Yang
    Citation: BMC Complementary and Alternative Medicine 2012 12:5
    Content type: Research article Published on:

  23. Integrative Medicine (IM) is an emerging field in paediatrics, especially in the USA. The purpose of the present study was to assess the attitudes and beliefs of Youth Health Care (YHC) physicians in the Nethe...

    Authors: Miek C Jong, Marja van Vliet, Susan Huttenhuis, Désirée van der Veer and Silvia van den Heijkant
    Citation: BMC Complementary and Alternative Medicine 2012 12:4
    Content type: Research article Published on:

  24. Dengue fever regardless of its serotypes has been the most prevalent arthropod-borne viral diseases among the world population. The development of a dengue vaccine is complicated by the antibody-dependent enha...

    Authors: Leon IC Tang, Anna PK Ling, Rhun Y Koh, Soi M Chye and Kenny GL Voon
    Citation: BMC Complementary and Alternative Medicine 2012 12:3
    Content type: Research article Published on:

  25. Complementary and alternative medicine (CAM) is common in patients with chronic disease such as diabetes mellitus. The primary objective of the study was to determine the overall prevalence and type of CAM use...

    Authors: Kiran Manya, Bernard Champion and Trisha Dunning
    Citation: BMC Complementary and Alternative Medicine 2012 12:2
    Content type: Research article Published on:

  26. Although use of complementary and alternative medicine (CAM) among cancer patients has been described previously, prevalence of use has not commonly been compared to other disease groups in a true population s...

    Authors: Agnete E Kristoffersen, Arne J Norheim and Vinjar M Fønnebø
    Citation: BMC Complementary and Alternative Medicine 2012 12:1
    Content type: Research article Published on:

  27. In the United States, it is estimated that 40% of adults utilize complementary and alternative medicine (CAM) therapies. Recently, national surveys report that over 90 million adults have inadequate health lit...

    Authors: Sujeev S Bains and Leonard E Egede
    Citation: BMC Complementary and Alternative Medicine 2011 11:138
    Content type: Research article Published on:

  28. Herb mixtures are widely used as an alternative to hormonal therapy in China for treatment of the menopausal syndrome. However, composition of these herb mixtures are complex and their working mechanism is oft...

    Authors: Lian-wei Xu, Lan Kluwe, Ting-ting Zhang, Sheng-nan Li, Yan-yan Mou, Zhen Sang, Jun Ma, Xiong Lu and Zhuo-jun Sun
    Citation: BMC Complementary and Alternative Medicine 2011 11:137
    Content type: Research article Published on:

  29. Available measures of patient-reported outcomes for complementary and alternative medicine (CAM) inadequately capture the range of patient-reported treatment effects. The Self-Assessment of Change questionnair...

    Authors: Jennifer J Thompson, Kimberly L Kelly, Cheryl Ritenbaugh, Allison L Hopkins, Colette M Sims and Stephen J Coons
    Citation: BMC Complementary and Alternative Medicine 2011 11:136
    Content type: Research article Published on:

  30. Patients receiving complementary and alternative medicine (CAM) therapies often report shifts in well-being that go beyond resolution of the original presenting symptoms. We undertook a research program to dev...

    Authors: Cheryl Ritenbaugh, Mimi Nichter, Mark A Nichter, Kimberly L Kelly, Colette M Sims, Iris R Bell, Heide M Castañeda, Charles R Elder, Mary S Koithan, Elizabeth G Sutherland, Marja J Verhoef, Sarah L Warber and Stephen J Coons
    Citation: BMC Complementary and Alternative Medicine 2011 11:135
    Content type: Research article Published on:

  31. Head and neck squamous cell carcinoma (HNSCC) is responsible for over 20,000 deaths every year in United States. Most of the deaths are due, in large part, to its propensity to metastasize. We have examined th...

    Authors: Qian Sun, Ram Prasad, Eben Rosenthal and Santosh K Katiyar
    Citation: BMC Complementary and Alternative Medicine 2011 11:134
    Content type: Research article Published on:

  32. Exercise stress was shown to increase oxidative stress in rats. It lacks reports of increased protection afforded by dietary antioxidant supplements against ROS production during exercise stress. We evaluated ...

    Authors: Sérvio A Bucioli, Luiz Carlos de Abreu, Vitor E Valenti, Claudio Leone and Helio Vannucchi
    Citation: BMC Complementary and Alternative Medicine 2011 11:133
    Content type: Research article Published on:

  34. The use of Complementary and Alternative medicine (CAM) has increased over the past years. In Germany, many general practitioners (GPs) use CAM in their daily practice. However, little is known about possible ...

    Authors: Stefanie Joos, Berthold Musselmann, Joachim Szecsenyi and Katja Goetz
    Citation: BMC Complementary and Alternative Medicine 2011 11:131
    Content type: Research article Published on:

  35. Several plants traditionally used in treatment of a variety of infections in South Africa are reported in ethnobotanical surveys. Many of these plants including Ziziphus mucronata subsp. mucronata lack scientific...

    Authors: Olufunmiso O Olajuyigbe and Anthony J Afolayan
    Citation: BMC Complementary and Alternative Medicine 2011 11:130
    Content type: Research article Published on:

  36. Gum resins obtained from trees of the Burseraceae family (Boswellia sp.) are important ingredients in incense and perfumes. Extracts prepared from Boswellia sp. gum resins have been shown to possess anti-inflamma...

    Authors: Mahmoud M Suhail, Weijuan Wu, Amy Cao, Fadee G Mondalek, Kar-Ming Fung, Pin-Tsen Shih, Yu-Ting Fang, Cole Woolley, Gary Young and Hsueh-Kung Lin
    Citation: BMC Complementary and Alternative Medicine 2011 11:129
    Content type: Research article Published on:

  37. Fundamental in traditional postpartum recovery in Lao PDR is the use of hotbeds, mother roasting, steam sauna and steam baths. During these treatments medicinal plants play a crucial role, but little has been ...

    Authors: Hugo J de Boer, Vichith Lamxay and Lars Björk
    Citation: BMC Complementary and Alternative Medicine 2011 11:128
    Content type: Research article Published on:

  38. Acupuncture is widely-used to treat patients with low back pain, despite insufficient evidence of the technique's efficacy for acute back pain. Motion style acupuncture treatment (MSAT) is a non-traditional ac...

    Authors: Joon-Shik Shin, In-Hyuk Ha, Tae-Gyu Lee, Youngkwon Choi, Byoung-Yoon Park, Me-riong Kim and Myeong Soo Lee
    Citation: BMC Complementary and Alternative Medicine 2011 11:127
    Content type: Study protocol Published on:

  39. Insulin deficiency is the prime basis of all diabetic manifestations and agents that can bring about insulin secretion would be of pivotal significance for cure of diabetes. To test this hypothesis, we carried...

    Authors: Ansarullah, Bhavna Bharucha, Mitesh Dwivedi, Naresh C Laddha, Rasheedunnisa Begum, Anandwardhan A Hardikar and AV Ramachandran
    Citation: BMC Complementary and Alternative Medicine 2011 11:126
    Content type: Research article Published on:

  40. Allergic disease is a consequence of exposure to normally innocuous substances that elicit the activation of mast cells. Mast-cell-mediated allergic response is involved in many diseases such as anaphylaxis, u...

    Authors: Dae-Young Kwon, Hye-Jeong Yang, Min-Jeong Kim, Hee-Joo Kang, Hyun-Jin Kim, Ki-Chan Ha, Hyang-Im Back, Sun-Young Kim, Eun-Ok Park, Min-Gul Kim, Seok-Kwon Yun, Soo-Wan Chae and Back-Hwan Cho
    Citation: BMC Complementary and Alternative Medicine 2011 11:125
    Content type: Study protocol Published on:

  41. Moxibustion is an ancient traditional medicine using burning mugworts to stimulate acupuncture points. The aim of this study was to investigate the safety and efficacy of moxibustion for the treatment of const...

    Authors: Ji-Eun Park, Jae-Uk Sul, Kyungwon Kang, Byung-Cheul Shin, Kwon-Eui Hong and Sun-Mi Choi
    Citation: BMC Complementary and Alternative Medicine 2011 11:124
    Content type: Research article Published on:

  42. Botanical medicines are increasingly combined with chemotherapeutics as anticancer drug cocktails. This study aimed to assess the chemotherapeutic potential of an extract of Taxus cuspidata (TC) needles and twigs...

    Authors: Weihu Shang, Jinping Qiao, Chenxin Gu, Wei Yin, Jinglei Du, Wei Wang, Meilin Zhu, Mei Han and Weidong Lu
    Citation: BMC Complementary and Alternative Medicine 2011 11:123
    Content type: Research article Published on:

  43. The local treatment of burn wounds has long been a subject of debate. The objective of this study was to compare the cost and the effectiveness of Moist Exposed Burn Ointment -MEBO versus a combination of povidon...

    Authors: Vilelmine J Carayanni, Evangelia G Tsati, Georgia C H Spyropoulou, Fotini N Antonopoulou and John D Ioannovich
    Citation: BMC Complementary and Alternative Medicine 2011 11:122
    Content type: Research article Published on:

  44. Very little research has explored the factors that influence interest in complementary and alternative medicine (CAM) treatments. We surveyed persons with sub-optimally controlled type 2 diabetes to evaluate p...

    Authors: Ryan Bradley, Karen J Sherman, Sheryl Catz, Carlo Calabrese, Luesa Jordan, Lou Grothaus and Dan C Cherkin
    Citation: BMC Complementary and Alternative Medicine 2011 11:121
    Content type: Research article Published on:

  45. Salvia miltiorrhiza (SM) has long been used as a traditional oriental medicine for cardiovascular disease. Accumulating evidence also indicates that SM has anti-osteoporotic effects. This study was conducted to ...

    Authors: Yan Cui, Bidur Bhandary, Anu Marahatta, Geum-Hwa Lee, Bo Li, Do-Sung Kim, Soo-Wan Chae, Hyung-Ryong Kim and Han-Jung Chae
    Citation: BMC Complementary and Alternative Medicine 2011 11:120
    Content type: Research article Published on:

  46. Candida-associated denture stomatitis is a frequent infectious disease. Treatment of this oral condition is difficult because failures and recurrences are common. The aim of this study was to test the in vitro a...

    Authors: Cristina Marcos-Arias, Elena Eraso, Lucila Madariaga and Guillermo Quindós
    Citation: BMC Complementary and Alternative Medicine 2011 11:119
    Content type: Research article Published on:

  47. Substantial recent research examines the efficacy of many types of complementary and alternative (CAM) therapies. However, outcomes associated with the "real-world" use of CAM has been largely overlooked, desp...

    Authors: Lynn L DeBar, Charles Elder, Cheryl Ritenbaugh, Mikel Aickin, Rick Deyo, Richard Meenan, John Dickerson, Jennifer A Webster and Bobbi Jo Yarborough
    Citation: BMC Complementary and Alternative Medicine 2011 11:118
    Content type: Study protocol Published on:

  48. Over three-quarter of the world's population is using herbal medicines with an increasing trend globally. Herbal medicines may be beneficial but are not completely harmless.

    Authors: Ibrahim Adekunle Oreagba, Kazeem Adeola Oshikoya and Mercy Amachree
    Citation: BMC Complementary and Alternative Medicine 2011 11:117
    Content type: Research article Published on:

  49. In Germany, Iscucin® Populi (IP), a preparation from mistletoe growing on the poplar tree, is used in cancer therapy while Viscum Mali e planta tota (VM), a preparation from mistletoe growing on the apple tree, i...

    Authors: Roman Huber, Holger Lüdtke, Johannes Wieber and Christiane Beckmann
    Citation: BMC Complementary and Alternative Medicine 2011 11:116
    Content type: Research article Published on:

  50. Enhancement of antimicrobial plant products e.g. pomegranate extract by copper (II) sulphate is known. Such combinations have applications in various settings, including the identification of novel compositions t...

    Authors: Andrew C Holloway, Simon WJ Gould, Mark D Fielder, Declan P Naughton and Alison F Kelly
    Citation: BMC Complementary and Alternative Medicine 2011 11:115
    Content type: Research article Published on:
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