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  1. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results from a progressive loss of motor neurons. Familial ALS (fALS) is caused by missense mutations in Cu, Zn-superoxide dismutase 1 (S...

    Authors: Seon Hwy Kim, So Young Jung, Kang-Woo Lee, Sun Hwa Lee, MuDan Cai, Sun-Mi Choi and Eun Jin Yang
    Citation: BMC Complementary and Alternative Medicine 2013 13:179
  2. There are reports of improved metabolic outcomes due to consumption of germinated brown rice (GBR). Many of the functional effects of GBR can be linked to its high amounts of antioxidants. Interestingly, dieta...

    Authors: Nur Hanisah Azmi, Norsharina Ismail, Mustapha Umar Imam and Maznah Ismail
    Citation: BMC Complementary and Alternative Medicine 2013 13:177
  3. Gamijinhae-tang (GJHT) has long been used in Korea to treat respiratory diseases. The therapeutic effect of GJHT is likely associated with its anti-inflammatory activity. However, the precise mechanisms underl...

    Authors: Sung-Hwa Sohn, HaRyeon Jang, Youngeun Kim, Young Pyo Jang, Seung-Hun Cho, Heejae Jung, Sungki Jung and Hyunsu Bae
    Citation: BMC Complementary and Alternative Medicine 2013 13:176
  4. Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycaemia generally associated with oxidative stress. The present study aims at evaluating the antioxidant and antidiabetic potential...

    Authors: Clautilde Mofor Teugwa, Pascaline Chouadeu Mejiato, Denis Zofou, Bruno Tugnoua Tchinda and Fabrice Fekam Boyom
    Citation: BMC Complementary and Alternative Medicine 2013 13:175
  5. Traditional Chinese medicines have been used for anti-asthma treatment for several centuries in many Asian countries, and have been shown to effectively relieve symptoms. Our previous study demonstrated that a...

    Authors: Hung-Chou Chang, Cheng-Chung Gong, Chi-Lim Chan and Oi-Tong Mak
    Citation: BMC Complementary and Alternative Medicine 2013 13:174
  6. XinJiErKang (XJEK), a Chinese herbal formula, is identified as an effective preparation to treat coronary heart disease and myocarditis. The aim of the study is to investigate the anti-hypertensive effects of ...

    Authors: Ting-ting Yu, Kun Guo, Han-chun Chen, Chao-zong Lan, Jian Wang, Ling-ling Huang, Xing-hui Wang, Zhen Zhang and Shan Gao
    Citation: BMC Complementary and Alternative Medicine 2013 13:173
  7. Yoga seems to be an effective means to cope with a variety of internalmedicine conditions. While characteristics of yoga users have beeninvestigated in the general population, little is known about predictors ...

    Authors: Holger Cramer, Romy Lauche, Jost Langhorst, Anna Paul, Andreas Michalsen and Gustav Dobos
    Citation: BMC Complementary and Alternative Medicine 2013 13:172
  8. The objective of the present study was to determine the phytochemical content and the protective effect of red grape skin extract (RGSE) against fructose-mediated protein oxidation. In addition, RGSE was scree...

    Authors: Nattha Jariyapamornkoon, Sirintorn Yibchok-anun and Sirichai Adisakwattana
    Citation: BMC Complementary and Alternative Medicine 2013 13:171
  9. Banhabaekchulchunma-tang (hange-byakujutsu-tenma-to in Japanese and banxia-baizhu-tianma-tang in Chinese) is a mixture of fourteen herbs. It is used traditionally for the treatment of anemia, anorexia, general...

    Authors: In-Sik Shin, Woo-Young Jeon, Hyeun-Kyoo Shin, Sin-Woo Cha and Mee-Young Lee
    Citation: BMC Complementary and Alternative Medicine 2013 13:170
  10. In order to effectively target and provide individualised patient support strategies it is crucial to have a comprehensive picture of those presenting for services. The purpose of this study was to determine t...

    Authors: Bonnie J Furzer, Kemi E Wright, Anna S Petterson, Karen E Wallman, Timothy R Ackland and David JL Joske
    Citation: BMC Complementary and Alternative Medicine 2013 13:169
  11. Syzygium campanulatum Korth (Myrtaceae) is an evergreen shrub rich in phenolics, flavonoid antioxidants, and betulinic acid. This study sought to investigate antiangiogenic and anti-colon cancer effects of S.C. ...

    Authors: Abdalrahim FA Aisha, Zhari Ismail, Khalid M Abu-Salah, Jamshed M Siddiqui, Gheniya Ghafar and Amin Malik Shah Abdul Majid
    Citation: BMC Complementary and Alternative Medicine 2013 13:168
  12. In Pakistan Fagonia olivieri (Zygophyllaceae) is commonly used in the indigenous system of medicine for treatment of conditions like diabetes, cancer, fever, asthma, toothache, stomach troubles and kidney disorde...

    Authors: Umbreen Rashid, Muhammad Rashid Khan, Shumaila Jan, Jasia Bokhari and Naseer Ali Shah
    Citation: BMC Complementary and Alternative Medicine 2013 13:167
  13. Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called “Kayakalp”, commonly applied to treat skin disorde...

    Authors: Chung Yeng Looi, Bushra Moharram, Mohammadjavad Paydar, Yi Li Wong, Kok Hoong Leong, Khalit Mohamad, Aditya Arya, Won Fen Wong and Mohd Rais Mustafa
    Citation: BMC Complementary and Alternative Medicine 2013 13:166
  14. Aromatherapy and hand massage therapies have been reported to have some benefit for people with dementia who display behavioural symptoms; however there are a number of limitations of reported studies. The aim...

    Authors: Chieh-Yu Fu, Wendy Moyle and Marie Cooke
    Citation: BMC Complementary and Alternative Medicine 2013 13:165
  15. In response to the propagation of bacteria resistant to many antibiotics also called multi-drug resistant (MDR) bacteria, the discovery of new and more efficient antibacterial agents is primordial. The present...

    Authors: Doriane E Djeussi, Jaurès AK Noumedem, Jackson A Seukep, Aimé G Fankam, Igor K Voukeng, Simplice B Tankeo, Antoine HL Nkuete and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2013 13:164
  16. Morella serata is a South African medicinal plant used in the treatment of microbial infections and to enhance male sexual performance. There is dearth of information in scientific literature on its efficacy and...

    Authors: Anofi Omotayo Tom Ashafa
    Citation: BMC Complementary and Alternative Medicine 2013 13:163
  17. Several plant extracts from Rutaceae family are currently used to the management of sickle cell disorder (SCD) in the African. Few reports have shown that extracts from Zanthoxyllum or Fagara genus demonstrated a...

    Authors: Nanfack Pauline, Biapa Nya Prosper Cabral, Pieme Constant Anatole, Ama Moor Vicky Jocelyne, Moukette Bruno and Ngogang Yonkeu Jeanne
    Citation: BMC Complementary and Alternative Medicine 2013 13:162
  18. To investigate the effects of treatment with Multi component Chinese Medicine Jinzhida (JZD) on behavioral deficits in diabetes-associated cognitive decline (DACD) rats and verify our hypothesis that JZD treat...

    Authors: Xiao-Hui Chang, Li-Na Liang, Li-Bin Zhan, Xiao-Guang Lu, Xiang Shi, Xin Qi, Zhao-Lan Feng, Mei-Juan Wu, Hua Sui, Lu-Ping Zheng, Fu-Liang Zhang, Jie Sun, Chang-Chuan Bai, Nan Li and Guo-Zhu Han
    Citation: BMC Complementary and Alternative Medicine 2013 13:161
  19. The liver plays an essential role in the body by regulating several important metabolic functions. Liver injury is associated with the distortion of these functions causing many health problems. Pharmaceutical...

    Authors: Zahra A Amin, Mohammed A Alshawsh, Mustafa Kassim, Hapipah M Ali and Mahmood A Abdulla
    Citation: BMC Complementary and Alternative Medicine 2013 13:160
  20. Ayurved Siriraj Brand Wattana formula (AVS073), a Thai herbal formula, has traditionally been used for health promotion and prevention of age-related problems. Ultraviolet A (UVA) is recognized to play a vital...

    Authors: Uraiwan Panich, Thanyawan Pluemsamran, Vanida Tangsupa-a-nan, Jantanee Wattanarangsan, Rattana Phadungrakwittaya, Pravit Akarasereenont and Tawee Laohapand
    Citation: BMC Complementary and Alternative Medicine 2013 13:159
  21. In the present study, extracts prepared from the leaves of Rhus parviflora Roxb. (Anacardiaceae) were evaluated for their anti-HIV activity, which have been traditionally used for the treatment of neurological di...

    Authors: Manoj Modi, Nutan, Boskey Pancholi, Shweta Kulshrestha, Ajay Kumar Singh Rawat, Swadesh Malhotra and Satish Kumar Gupta
    Citation: BMC Complementary and Alternative Medicine 2013 13:158
  22. Senescence of the neurons is believed to be a focal factor in the development of age-related neurodegenerative diseases such as Alzheimer’s disease. Diminutions in the levels of nerve growth factor (NGF) lead ...

    Authors: Syntyche Ling-Sing Seow, Murali Naidu, Pamela David, Kah-Hui Wong and Vikineswary Sabaratnam
    Citation: BMC Complementary and Alternative Medicine 2013 13:157
  23. Registered dietitians (RDs) play a key role in disseminating information about nutrition and intervening in nutrition-related disorders in the Canadian context. Natural health products (NHPs) are increasingly ...

    Authors: Kristine Hirschkorn, Rishma Walji and Heather Boon
    Citation: BMC Complementary and Alternative Medicine 2013 13:156
  24. The present study was carried out to assess the phytochemical and anti-dermatophytic effect of the leaf and bark extracts of Xylosma longifolium Clos. The leaf and stem bark are used by the indigenous people of M...

    Authors: Wangkheirakpam Radhapiyari Devi, S Brojendro Singh and Chingakham B Singh
    Citation: BMC Complementary and Alternative Medicine 2013 13:155
  25. Arecae semen, the dried slice of areca nuts, is a traditional Chinese medicine used to treat intestinal parasitosis, rectal tenesmus and diarrhea. Areca nuts contain a rich amount of polyphenols that have been s...

    Authors: Chia-Chi Wang, Yu-Ru Lin, Mei-Hsiu Liao and Tong-Rong Jan
    Citation: BMC Complementary and Alternative Medicine 2013 13:154
  26. There are few studies of the prevalence and patterns of herbal and dietary supplement (HDS) use in patients with chronic kidney disease (CKD), although many researchers and health professionals worldwide have ...

    Authors: Mayuree Tangkiatkumjai, Helen Boardman, Kearkiat Praditpornsilpa and Dawn M Walker
    Citation: BMC Complementary and Alternative Medicine 2013 13:153
  27. Formaldehyde can induce misfolding and aggregation of Tau protein and β amyloid protein, which are characteristic pathological features of Alzheimer’s disease (AD). An increase in endogenous formaldehyde conce...

    Authors: Ping Sun, Jin-yan Chen, Jiao Li, Meng-ru Sun, Wei-chuan Mo, Kai-li Liu, Yan-yan Meng, Ying Liu, Feng Wang, Rong-qiao He and Qian Hua
    Citation: BMC Complementary and Alternative Medicine 2013 13:152
  28. Honey has been identified as a potential alternative to the widespread use of antibiotics, which are of significant concern considering the emergence of resistant bacteria. In this context, this study aimed to...

    Authors: Renah Boanerges de Queiroz Pimentel, Cristovão Alves da Costa, Patrícia Melchionna Albuquerque and Sergio Duvoisin Junior
    Citation: BMC Complementary and Alternative Medicine 2013 13:151
  29. Angiogenesis is closely related to the growth, invasion and metastasis of tumors, also considered as the key target of anticancer therapy. Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, ...

    Authors: Zhi-Jun Dai, Wang-Feng Lu, Jie Gao, Hua-Feng Kang, Yu-Guang Ma, Shu-Qun Zhang, Yan Diao, Shuai Lin, Xi-Jing Wang and Wen-Ying Wu
    Citation: BMC Complementary and Alternative Medicine 2013 13:150
  30. Extracts of leaves from Clerodendrum have been used for centuries to treat a variety of medicinal problems in tropical Africa. However, little is known about the high-molecular weight active components conferring...

    Authors: Koffi Kouakou, Igor A Schepetkin, SangMu Jun, Liliya N Kirpotina, Ahoua Yapi, Daria S Khramova, David W Pascual, Yury S Ovodov, Mark A Jutila and Mark T Quinn
    Citation: BMC Complementary and Alternative Medicine 2013 13:149
  31. Limited study on the use of complementary alternative medicine (CAM) among patients with diabetes mellitus (DM), particularly in primary -care settings. This study seeks to understand the prevalence, types, ex...

    Authors: Siew Mooi Ching, Zainul Amiruddin Zakaria, Fuziah Paimin and Mehrdad Jalalian
    Citation: BMC Complementary and Alternative Medicine 2013 13:148
  32. In Cameroon herbs are traditionally used to meet health care needs and plans are on the way to integrate traditional medicine in the health care system, even though the plans have not been put into action yet....

    Authors: Fidele Ntie-Kang, Lydia Likowo Lifongo, Luc Meva’a Mbaze, Nnange Ekwelle, Luc C Owono Owono, Eugene Megnassan, Philip N Judson, Wolfgang Sippl and Simon M N Efange
    Citation: BMC Complementary and Alternative Medicine 2013 13:147
  33. Chronic pain affects nearly 116 million American adults at an estimated cost of up to $635 billion annually and is the No. 1 condition for which patients seek care at integrative medicine clinics. In our Study...

    Authors: Donald I Abrams, Rowena Dolor, Rhonda Roberts, Constance Pechura, Jeffery Dusek, Sandi Amoils, Steven Amoils, Kevin Barrows, Joel S Edman, Joyce Frye, Erminia Guarneri, Ben Kligler, Daniel Monti, Myles Spar and Ruth Q Wolever
    Citation: BMC Complementary and Alternative Medicine 2013 13:146
  34. Rhaphidophora korthalsii (Araceae) is a root-climber plant which has been widely used in Chinese traditional medicine for cancer and skin disease treatment. Previous reports have recorded its immunomodulatory ef...

    Authors: Swee Keong Yeap, Abdul Rahman Omar, Wan Yong Ho, Boon Kee Beh, Abdul Manaf Ali and Noorjahan Banu Alitheen
    Citation: BMC Complementary and Alternative Medicine 2013 13:145
  35. Constitutive activation of STAT3 is one of the major oncogenic pathways involved in the development of various types of malignancies including colorectal cancer (CRC); and thus becomes a promising therapeutic ...

    Authors: Wei Lin, Liangpu Zheng, Qunchuan Zhuang, Jinyan Zhao, Zhiyun Cao, Jianwei Zeng, Shan Lin, Wei Xu and Jun Peng
    Citation: BMC Complementary and Alternative Medicine 2013 13:144
  36. Maytenus royleanus is traditionally used in gastro-intestinal disorders. The aim of this study was to evaluate the methanol extract of leaves and its derived fractions for various antioxidant assays and for its ...

    Authors: Maria Shabbir, Muhammad Rashid Khan and Naima Saeed
    Citation: BMC Complementary and Alternative Medicine 2013 13:143
  37. The use of plants and their derived substances increases day by day for the discovery of therapeutic agents owing to their versatile applications. Current research is directed towards finding naturally-occurri...

    Authors: Shafiqul Islam, Samima Nasrin, Muhammad Ali Khan, ASM Sakhawat Hossain, Farhadul Islam, Proma Khandokhar, M Nurul Haque Mollah, Mamunur Rashid, Golam Sadik, Md Aziz Abdur Rahman and AHM Khurshid Alam
    Citation: BMC Complementary and Alternative Medicine 2013 13:142
  38. Growing evidence shows that herb medicines have some anti-osteoporotic effects, the mechanism underlying is unknown. This study aims to investigate the therapeutic effect of Chinese herb supplements on rats th...

    Authors: Meijie Liu, Gary Guishan Xiao, Peijing Rong, Jiazi Dong, Zhiguo Zhang, Hongyan Zhao, Jingru Teng, Hongxia Zhao, Jinghua Pan, Yan Li, Qinglin Zha, Ying Zhang and Dahong Ju
    Citation: BMC Complementary and Alternative Medicine 2013 13:141
  39. Stress caused by free radicals accumulation result into many hazardous diseases. A number of investigations are focusing to find out the plant oriented natural antioxidant moieties. The basic aim of this resea...

    Authors: Bushra Ahmad, Muhammad Rashid Khan, Naseer Ali Shah and Rahmat Ali Khan
    Citation: BMC Complementary and Alternative Medicine 2013 13:140
  40. The purpose of this investigation was to determine if black tea extract (BTE), consisting primarily of flavanol compounds called theaflavins, could inhibit herpes simplex virus type-1 (HSV-1) infection in cult...

    Authors: Anthony Cantatore, Sade D Randall, Daniel Traum and Sandra D Adams
    Citation: BMC Complementary and Alternative Medicine 2013 13:139
  41. Rubus fruticosus is used in tribal medicine as anthelmintic and an antispasmodic. In the current work, we investigated the anthelmintic and antispasmodic activities of crude methanol extract of fruits of R. frut...

    Authors: Niaz Ali, Umer Aleem, Syed Wadood Ali Shah, Ismail Shah, Muhammad Junaid, Ghayour Ahmed, Waqar Ali and Mehreen Ghias
    Citation: BMC Complementary and Alternative Medicine 2013 13:138
  42. Soshiho-tang (SH; Chinese name, Xiao-Chai-Hu-Tang; Japanese name, Shosaiko-to) is a traditional Korean, Chinese, and Japanese medicine, which has been used to treat various conditions, including hepatitis, liv...

    Authors: Jung-Jin Lee, Taesoo Kim, Won-Kyung Cho and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:137
  43. High-cholesterol diet (HCD) increases the oxidative stress in different tissues leading to many diseases. Rutin (RT) is a natural flavonoid (vitamin p), which possesses an antioxidant activity with protective ...

    Authors: Salem S Al-Rejaie, Abdulaziz M Aleisa, Mohamed M Sayed-Ahmed, Othman A AL-Shabanah, Hatem M Abuohashish, Mohammed M Ahmed, Khaled A Al-Hosaini and Mohamed M Hafez
    Citation: BMC Complementary and Alternative Medicine 2013 13:136
  44. We have previously reported that aerial parts of Tylophora hirsuta have antispasmodic profile. The current work is an attempt for isolation of pharmacologically active compound(s) that contribute for its antispas...

    Authors: Niaz Ali
    Citation: BMC Complementary and Alternative Medicine 2013 13:135
  45. Transcutaneous electrical nerve stimulation (TENS) is a non-pharmacologic treatment for pain relief. In previous animal studies, TENS effectively alleviated Complete Freund’s Adjuvant (CFA)- or carrageenan-ind...

    Authors: Jun-Fan Fang, Yi Liang, Jun-Ying Du and Jian-Qiao Fang
    Citation: BMC Complementary and Alternative Medicine 2013 13:134
  46. The plant genus Fallopia is well-known in Chinese traditional medicine and includes many species that contain bioactive compounds, namely phytoestrogens. Consumption of phytoestrogens may be linked to decreased i...

    Authors: Jennifer C Brennan, Michael S Denison, Dirk M Holstege, Prokopios Magiatis, Jerry L Dallas, Elisa G Gutierrez, Anatoly A Soshilov and James R Millam
    Citation: BMC Complementary and Alternative Medicine 2013 13:133
  47. Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China. Due to its worldwide use, potential impact on healthcare and opportunities for new drug development, TCM is also of great...

    Authors: Qihe Xu, Rudolf Bauer, Bruce M Hendry, Tai-Ping Fan, Zhongzhen Zhao, Pierre Duez, Monique SJ Simmonds, Claudia M Witt, Aiping Lu, Nicola Robinson, De-an Guo and Peter J Hylands
    Citation: BMC Complementary and Alternative Medicine 2013 13:132
  48. Women with polycystic ovary syndrome (PCOS) have symptoms of depression and anxiety and impaired health related quality of life (HRQoL). Here we test the post-hoc hypothesis that acupuncture and exercise impro...

    Authors: Elisabet Stener-Victorin, Göran Holm, Per Olof Janson, Deborah Gustafson and Margda Waern
    Citation: BMC Complementary and Alternative Medicine 2013 13:131
  49. Antibacterial activity of honey is mainly dependent on a combination of its peroxide activity and non-peroxide components. This study aims to investigate antibacterial activity of five varieties of Malaysian h...

    Authors: Mohd Izwan Zainol, Kamaruddin Mohd Yusoff and Mohd Yasim Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2013 13:129