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  1. Marine environment is inestimable for their chemical and biological diversity and therefore is an extraordinary resource for the discovery of new anticancer drugs. Recent development in elucidation of the mech...

    Authors: Satyajit Patra and Meenakshi Sundaram Muthuraman
    Citation: BMC Complementary and Alternative Medicine 2013 13:331
  2. The 2002, 2007, and 2012 complementary medicine questionnaires fielded on the National Health Interview Survey provide the most comprehensive data on complementary medicine available for the United States. The...

    Authors: Barbara J Stussman, Christina D Bethell, Caroline Gray and Richard L Nahin
    Citation: BMC Complementary and Alternative Medicine 2013 13:328
  3. Many studies have explored the relationship between skin microcirculation and meridian activation. However, few studies have examined blood perfusion coherence along the meridians, and other studies have sugge...

    Authors: Guangjun Wang, Yuying Tian, Shuyong Jia, Wenting Zhou and Weibo Zhang
    Citation: BMC Complementary and Alternative Medicine 2013 13:327
  4. Melastoma malabathricum L. (Melastomaceae) is a small shrub with various medicinal uses. The present study was carried out to determine the hepatoprotective activity of methanol extract of M. malabathricum leave...

    Authors: Siti Syariah Mamat, Mohamad Fauzi Fahmi Kamarolzaman, Farhana Yahya, Nur Diyana Mahmood, Muhammad Syahmi Shahril, Krystal Feredoline Jakius, Norhafizah Mohtarrudin, Siew Mooi Ching, Deny Susanti, Muhammad Taher and Zainul Amiruddin Zakaria
    Citation: BMC Complementary and Alternative Medicine 2013 13:326
  5. Bufalin is a major active compound of cinobufacini, which comes from dried toad venom and has been used for treatments of various cancers in China for many years. A number of studies have demonstrated that buf...

    Authors: Xiao-feng Zhai, Fan-fu Fang, Qun Liu, Yong-bin Meng, Yu-yu Guo and Zhe Chen
    Citation: BMC Complementary and Alternative Medicine 2013 13:325
  6. Danggui-Jakyak-San (DJS), a traditional herbal prescription, has been used to treat insufficient blood supplies. Recently, regenerative medication for the treatment of cerebral ischemia has drawn the attention...

    Authors: Mi Deok Song, Dong Hyun Kim, Jong Min Kim, Hyung Eun Lee, Se Jin Park, Jong Hoon Ryu and Jae Hwan Lew
    Citation: BMC Complementary and Alternative Medicine 2013 13:324
  7. Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths reported worldwide. The incidence is higher in Asia and Africa, where there is greater endemic prevalence of hepatitis B and C. The de...

    Authors: Ravindran Jaganathan, Vijaya Ravinayagam, Sachdanandam Panchanadham and Shanthi Palanivelu
    Citation: BMC Complementary and Alternative Medicine 2013 13:323
  8. Ardisia pusilla A. DC., family Myrsinaceae, is a traditional Chinese medicine named Jiu Jie Long with a variety of pharmacological functions including anti-cancer activities. In this study, we purified a natural...

    Authors: Xiao-Fang Xu, Tao-Li Zhang, Song Jin, Rong Wang, Xin Xiao, Wei-Dong Zhang, Peng-Yuan Wang and Xiao-Juan Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:322
  9. Extracts from Potentilla species have been applied in traditional medicine and exhibit antioxidant, hypoglycemic, anti-inflammatory, antitumor and anti-ulcerogenic properties, but little has been known about the ...

    Authors: Shan-Shan Wang, Dong-Mei Wang, Wen-Jun Pu and Deng-Wu Li
    Citation: BMC Complementary and Alternative Medicine 2013 13:321
  10. Traditional Chinese medicine has been widely used for the treatment of recurrent miscarriage in China and other Asian countries for long time. We conducted this review to systematically summarize the evidences...

    Authors: Guo-Yan Yang, Hui Luo, Xing Liao and Jian-Ping Liu
    Citation: BMC Complementary and Alternative Medicine 2013 13:320
  11. There is little understanding of the reasons for the limited communication between patients and conventional healthcare professionals regarding patients’ use of complementary and alternative medicine (CAM). Th...

    Authors: Hsiao-Yun Chang, Huai-Lu Chang and Betty Siren
    Citation: BMC Complementary and Alternative Medicine 2013 13:319
  12. The use of complementary and alternative medicine (CAM) and complementary and alternative therapies (CAT) during pregnancy is increasing. Scientific evidence for CAM and CAT in the field of obstetrics mainly c...

    Authors: Ester Muñoz-Sellés, Antoni Vallès-Segalés and Josefina Goberna-Tricas
    Citation: BMC Complementary and Alternative Medicine 2013 13:318
  13. Main concerns for lactating women about medications include the safety of their breastfed infants and the potential effects of medication on quantity and quality of breast milk. While medicine treatments inclu...

    Authors: Tin Fei Sim, Jillian Sherriff, H Laetitia Hattingh, Richard Parsons and Lisa BG Tee
    Citation: BMC Complementary and Alternative Medicine 2013 13:317
  14. Glucosamine is commonly prescribed as a disease modulating agent in osteoarthritis. However, the evidence to date suggests that it has a limited impact on the clinical symptoms of the disease including joint p...

    Authors: Rose Galvin, Grainne Cousins, Fiona Boland, Nicola Motterlini, Kathleen Bennett and Tom Fahey
    Citation: BMC Complementary and Alternative Medicine 2013 13:316
  15. Lavender essential oil shows evidence of sedative properties in neurophysiological and animal studies but clinical trials of its effectiveness as a treatment of agitation in people with dementia have shown mix...

    Authors: Daniel W O’Connor, Barbara Eppingstall, John Taffe and Eva S van der Ploeg
    Citation: BMC Complementary and Alternative Medicine 2013 13:315
  16. Alpinia scabra, locally known as 'Lengkuas raya’, is an aromatic, perennial and rhizomatous herb from the family Zingiberaceae. It is a wild species which grows largely on mountains at moderate elevations in Pen...

    Authors: Annushuya Subba Reddy, Sri urestri Abd Malek, Halijah Ibrahim and Kae Shin Sim
    Citation: BMC Complementary and Alternative Medicine 2013 13:314
  17. Angiotensin I-converting enzyme (ACE) inhibitors have been reported to reduce mortality in patients with hypertension. Compared to chemosynthetic drugs, ACE inhibitors derived from natural sources such as food...

    Authors: Ching Ching Lau, Noorlidah Abdullah and Adawiyah Suriza Shuib
    Citation: BMC Complementary and Alternative Medicine 2013 13:313
  18. Gami-Cheongyeul-Sodok-Eum (GCSE), an herbal formula of traditional Korean medicine, comprises nine herb components. GCSE has various biological activities such as anti-inflammatory, anti-bacterial and anti-vir...

    Authors: Ji Sun Hwang, Jung-Eun Kim, Young-Beob Yu and Sin-Hyeog Im
    Citation: BMC Complementary and Alternative Medicine 2013 13:312
  19. Acupuncture is widely used to treat diabetic patients with dyspeptic symptoms suggestive of gastroparesis in China. We conducted this systematic review of randomized controlled trials (RCTs) to evaluate the ef...

    Authors: Mingxing Yang, Xiumin Li, Suhuan Liu, Zhipeng Li, Mei Xue, Dehong Gao, Xuejun Li and Shuyu Yang
    Citation: BMC Complementary and Alternative Medicine 2013 13:311
  20. Recently, considerable attention has been focused on exploring the potential antioxidant properties of plant extracts or isolated products of plant origin. Prunella vulgaris var. lilacina is widely distributed in...

    Authors: Yu-Jin Hwang, Eun-Ju Lee, Haeng-Ran Kim and Kyung-A Hwang
    Citation: BMC Complementary and Alternative Medicine 2013 13:310
  21. Buyang Huanwu Decoction (BYHWD), a traditional Chinese medicine formula, has been shown to exert a variety of pharmacological effects including neuroprotective properties. However, the mechanism of neuroprotectio...

    Authors: Lei Wang and Dian-Ming Jiang
    Citation: BMC Complementary Medicine and Therapies 2013 13:309
  22. To evaluate and compare effects of an integrative treatment (IT), therapeutic acupuncture (TA), and conventional treatment (CT) in alleviating symptoms of anxiety and depression in psychologically distressed p...

    Authors: Tina Arvidsdotter, Bertil Marklund and Charles Taft
    Citation: BMC Complementary and Alternative Medicine 2013 13:308
  23. Sasang constitutional medicine (SCM) is a type of tailored medicine that divides human beings into four Sasang constitutional (SC) types. Diagnosis of SC types is crucial to proper treatment in SCM. Voice char...

    Authors: Jun-Su Jang, Boncho Ku, Young-Su Kim, Jiho Nam, Keun Ho Kim and Jong Yeol Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:307
  24. Traditional Chinese eye exercises of acupoints involve acupoint self-massage. These have been advocated as a compulsory measure to reduce ocular fatigue, as well as to retard the development of myopia, among C...

    Authors: Zhong Lin, Balamurali Vasudevan, Vishal Jhanji, Tie Ying Gao, Ning Li Wang, Qi Wang, Ji Wang, Kenneth J Ciuffreda and Yuan Bo Liang
    Citation: BMC Complementary and Alternative Medicine 2013 13:306
  25. The present study evaluates the effects of extract of Musa sapientum fruit (MSE) on ulcer index, blood glucose level and gastric mucosal cytokines, TNF-α and IL-1β and growth factor, TGF-α (affected in diabetes a...

    Authors: Mohan Kumar, Manish Kumar Gautam, Amit Singh and Raj Kumar Goel
    Citation: BMC Complementary and Alternative Medicine 2013 13:305
  26. Aging is an inevitable process for all living organisms. During this process reactive oxygen species generation is increased which leads to the activation of hyaluronidase, collagenase and elastase, which can ...

    Authors: Gugulethu Ndlovu, Gerda Fouche, Malefa Tselanyane, Werner Cordier and Vanessa Steenkamp
    Citation: BMC Complementary and Alternative Medicine 2013 13:304
  27. Currently, there are no consistently effective chemotherapies for recurrent and inoperable meningiomas. Recently, cucurbitacin I (JSI-124), a naturally occurring tetracyclic triterpenoid compound used as folk ...

    Authors: Mahlon D Johnson, Mary J O’Connell and Kevin Walter
    Citation: BMC Complementary and Alternative Medicine 2013 13:303
  28. There have been many attempts to find an objective phenotype by Sasang constitutional types (SCTs) on an anatomical, physiological, and psychological basis, but there has been no research on total nasal resist...

    Authors: Dae Wui Yoon, Seung Ku Lee, Hyeryeon Yi, Jeong Hwa Hong, Miyazaki Soichiro, Si Woo Lee, Jong Yeol Kim and Chol Shin
    Citation: BMC Complementary and Alternative Medicine 2013 13:302
  29. Use of alternative medicine for chronic diseases such as hypertension is common in low as well as high income countries. This study estimated the proportion of people who were aware of their hypertension that ...

    Authors: Fred Nuwaha and Geofrey Musinguzi
    Citation: BMC Complementary and Alternative Medicine 2013 13:301
  30. Supported self-management, acupuncture and information can help reduce the symptoms of low back pain. These approaches are currently recommended by NICE guidance as treatment options for patients with persiste...

    Authors: Anna Cheshire, Marie Polley, David Peters and Damien Ridge
    Citation: BMC Complementary and Alternative Medicine 2013 13:300
  31. The present study was undertaken to evaluate the anti-depressive activity of turmerone after one-week administration by using a mouse forced swimming test (FST) and tail suspension test (TST).

    Authors: Jung-Chun Liao, Jen-Chieh Tsai, Chia-Yu Liu, Hui-Chi Huang, Lung-Yuan Wu and Wen-Huang Peng
    Citation: BMC Complementary and Alternative Medicine 2013 13:299
  32. Rhodiola crenulata (R. crenulata) is widely used to prevent acute mountain sickness in the Himalayan areas and in Tibet, but no scientific studies have previously examined its effectiveness. We conducted a rando...

    Authors: Te-Fa Chiu, Lisa Li-Chuan Chen, Deng-Huang Su, Hsiang-Yun Lo, Chung-Hsien Chen, Shih-Hao Wang and Wei-Lung Chen
    Citation: BMC Complementary and Alternative Medicine 2013 13:298
  33. Metabolic syndrome is a set of disorders that increases the risk of developing cardiovascular disease. The primary target of treatment of patients with metabolic syndrome is therapeutic lifestyle change. Numer...

    Authors: Hyang-Im Back, Ki-Chan Ha, Hye-Mi Kim, Min-Gul Kim, Ok-Kyeong Yu, Moon-Sun Byun, Do-Youn Jeong, Seong-Yeop Jeong, Youn-Soo Cha and Tae-Sun Park
    Citation: BMC Complementary and Alternative Medicine 2013 13:297
  34. Xanthium indicum stem is used in folk medicine of Bangladesh to control sugar in diabetic patients and to alleviate pain. The objective of the study was to evaluate antihyperglycemic and antinociceptive activity...

    Authors: Md Ezazul Haque, Shahnaz Rahman, Mohammed Rahmatullah and Rownak Jahan
    Citation: BMC Complementary and Alternative Medicine 2013 13:296
  35. Different patient groups are known to use herbal remedies and conventional drugs concomitantly (co-use). This poses a potential risk of herb-drug interaction through altering the drug’s pharmacokinetics or pha...

    Authors: Ane Djuv, Odd Georg Nilsen and Aslak Steinsbekk
    Citation: BMC Complementary and Alternative Medicine 2013 13:295
  36. Oxidative stress due to abnormal induction of reactive oxygen species (ROS) molecules is believed to be involved in the etiology of many diseases. Evidences suggest that ROS is involved in nephrotoxicity throu...

    Authors: Farkaad A Kadir, Normadiah M Kassim, Mahmood A Abdulla and Wageeh A Yehye
    Citation: BMC Complementary and Alternative Medicine 2013 13:294
  37. Community acupuncture is a recent innovation in acupuncture service delivery in the U.S. that aims to improve access to care through low-cost treatments in group-based settings. Patients at community acupunctu...

    Authors: Kimberly M Tippens, Maria T Chao, Erin Connelly and Adrianna Locke
    Citation: BMC Complementary and Alternative Medicine 2013 13:293
  38. Acne vulgaris is a chronic skin disorder leading to inflammation as a result of the production of reactive oxygen species due to the active involvement of Propionibacterium acnes (P. acnes) in the infection site ...

    Authors: Richa Sharma, Navneet Kishore, Ahmed Hussein and Namrita Lall
    Citation: BMC Complementary and Alternative Medicine 2013 13:292
  39. Tuberculosis (TB) is a global burden with one –third of the world’s population infected with the pathogen Mycobacterium tuberculosis complex and annually 1.4 million deaths occur due to the disease. This high inc...

    Authors: Abdella Gemechu, Mirutse Giday, Adane Worku and Gobena Ameni
    Citation: BMC Complementary and Alternative Medicine 2013 13:291
  40. The effect of seizure suppression by acupuncture of Feng-Chi (GB20) acupoints has been documented in the ancient Chinese literature, Lingshu Jing (Classic of the Miraculous Pivot), however, there is a lack of ...

    Authors: Pei-Lu Yi, Chin-Yu Lu, Chiung-Hsiang Cheng, Yi-Fong Tsai, Chung-Tien Lin and Fang-Chia Chang
    Citation: BMC Complementary and Alternative Medicine 2013 13:290
  41. The aim of this study was to evaluate the antimicrobial activity and the cytotoxicity of the ethanol crude extract, fractions and isolated compounds from the twigs of Eriosema robustum, a plant used for the treat...

    Authors: Maurice D Awouafack, Lyndy J McGaw, Sebastian Gottfried, Roukayatou Mbouangouere, Pierre Tane, Michael Spiteller and Jacobus N Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:289
  42. In this study, we investigate the proliferation of adult neural stem cells (NSCs) in a chronic unpredictable stress (CUS) rat model of depression, the effects of electroacupunture (EA) on depressive-like sympt...

    Authors: Liu Yang, Na Yue, Xiaocang Zhu, Qiuqin Han, Qiong Liu, Jin Yu and Gencheng Wu
    Citation: BMC Complementary and Alternative Medicine 2013 13:288
  43. Complementary and alternative medicine (CAM) is commonly used in China for the management of coronary artery disease (CAD). However, few studies have been conducted to investigate the prevalence, perceived eff...

    Authors: Fu-Yong Chu, Xue Yan, Ze Zhang, Xing-Jiang Xiong, Jie Wang and Hong-Xu Liu
    Citation: BMC Complementary and Alternative Medicine 2013 13:287
  44. Bioactivity-guided fractionation of extracts of Aglaia loheri Blanco (Meliaceae) yielded a cytotoxic isolate, termed Maldi 531.2[M + H]+. This phenolic ester was further investigated for its in vitro cytotoxicity...

    Authors: Else Dapat, Sonia Jacinto and Thomas Efferth
    Citation: BMC Complementary and Alternative Medicine 2013 13:286
  45. The Quinine tree (Rauvolfia caffra) is used as a medicinal plant among traditional communities in many countries to manage tumors and other diseases associated with oxidative stress. To validate indigenous knowle...

    Authors: Trizah K Milugo, Leonida K Omosa, James O Ochanda, Bethwell O Owuor, Fred A Wamunyokoli, Julius O Oyugi and Joel W Ochieng
    Citation: BMC Complementary and Alternative Medicine 2013 13:285
  46. Asystasia gangentica (A. gangetica) belongs to the family Acanthaceae. It is used to treat hypertension, rheumatism, asthma, diabetes mellitus, and as an anthelmintic in South Africa, India, Cameroun, Nigeria, a...

    Authors: Pierre Mugabo and Ismaila A Raji
    Citation: BMC Complementary and Alternative Medicine 2013 13:283
  47. Obesity causes metabolic disease and is a serious health problem around the world. Polygonum cuspidatum (POCU1b) has been used clinically for the treatment of constipation, gallstones, hepatitis, and inflammation...

    Authors: Young Sook Kim, Yun Mi Lee, Joo Hwan Kim and Jin Sook Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:282
  48. Bombax ceiba Linn., commonly called as Semal, is used in various gastro-intestinal disturbances. It contains Lupeol which inhibits PTP-1B, adipogenesis, TG synthesis and accumulation of lipids in adipocytes and ...

    Authors: Paras Gupta, Rohit Goyal, Yamini Chauhan and Pyare Lal Sharma
    Citation: BMC Complementary and Alternative Medicine 2013 13:281
  49. It is suggested that dietary phytosterols, such as β-sitosterol (ST), have cancer chemopreventive effects; however, studies are limited to support such claims. Here, we evaluated the efficacy of ST on three di...

    Authors: Shanthi Sri Vundru, Raosaheb K Kale and Rana P Singh
    Citation: BMC Complementary and Alternative Medicine 2013 13:280