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  1. An overdose of paracetamol is a frequent reason for liver and renal toxicity and possible death and curcumin has hepatoprotective properties against liver damage. The exact mechanism of such protection is not ...

    Authors: Mohamed Mohamed Soliman, Mohamed Abdo Nassan and Tamer Ahmed Ismail
    Citation: BMC Complementary and Alternative Medicine 2014 14:457
  2. Strychnos spinosa Lam. is a deciduous tree used in traditional medicine to treat infectious diseases. This study is designed to determine the antimicrobial, antioxidant and cytotoxic activities of extracts and f...

    Authors: Adamu Imam Isa, Maurice Ducret Awouafack, Jean Paul Dzoyem, Mohammed Aliyu, Rabiu AbduSsalam Magaji, Joseph Olusegun Ayo and Jacobus Nicolaas Eloff
    Citation: BMC Complementary and Alternative Medicine 2014 14:456
  3. Panax ginseng is a famous traditional medicine in Korea for its beneficial effect on obesity, cardiac and liver associated diseases. The aim of this study was to investigate the metabolite in Panax ginseng (P....

    Authors: Seung Ok Yang, Hae Ran Park, Eun Suk Sohn, Sang Won Lee, Hyung Don Kim, Young Chang Kim, Kee Hong Kim, Sae Won Na, Hyung-Kyoon Choi, Mariadhas Valan Arasu and Young Ock Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:455
  4. Agaricus brasiliensis (A. brasiliensis) is a medicinal mushroom that exerts various pharmacological actions. We previously demonstrated that different cultivation conditions altered the activity of the polypheno...

    Authors: Daisuke Yamanaka, Masuro Motoi, Akitomo Motoi and Naohito Ohno
    Citation: BMC Complementary and Alternative Medicine 2014 14:454
  5. Gal-geun-dang-gwi-tang (GGDGT), an herbal medicine, is used to treat hypertension, stroke, and other inflammatory disorders in the clinical setting. Recently, GGDGT was recognized by the Korea Institute of Ori...

    Authors: So Min Lee, Yun Jung Lee, Jung Hoon Choi, Min Chul Kho, Jung Joo Yoon, Sun Ho Shin, Dae Gill Kang and Ho Sub Lee
    Citation: BMC Complementary and Alternative Medicine 2014 14:453
  6. Sonchus arvesis is traditionally reported in various human ailments including hepatotoxicity in Pakistan. Presently we designed to assess the protective effects of methanolic extract of Sonchus arvesis against c...

    Authors: Huda Mohammad Alkreathy, Rahmat Ali Khan, Muhammad Rashid Khan and Sumaira Sahreen
    Citation: BMC Complementary and Alternative Medicine 2014 14:452
  7. Essential oils (EO) obtained from twenty medicinal and aromatic plants were evaluated for their antimicrobial activity against the oral pathogens Candida albicans, Fusobacterium nucleatum, Porphyromonas gingivali...

    Authors: Salete MF Bersan, Livia CC Galvão, Vivian FF Goes, Adilson Sartoratto, Glyn M Figueira, Vera LG Rehder, Severino M Alencar, Renata MT Duarte, Pedro L Rosalen and Marta CT Duarte
    Citation: BMC Complementary and Alternative Medicine 2014 14:451
  8. Caryocar brasiliense Camb (Pequi) is a typical Brazilian Cerrado fruit tree. Its fruit is used as a vitamin source for culinary purposes and as a source of oil for the manufacture of cosmetics. C. brasiliense su...

    Authors: Lilian FB Amaral, Patricia Moriel, Mary Ann Foglio and Priscila G Mazzola
    Citation: BMC Complementary and Alternative Medicine 2014 14:450
  9. What was the relationship of Fuzheng Huayu recipe (FZHY) inhibiting hepatocyte apoptosis and HSC activation at different stage of liver fibrosis? In order to answer this question, the study was carried out to ...

    Authors: Yan-yan Tao, Xiu-chuan Yan, Tao Zhou, Li Shen, Zu-long Liu and Cheng-hai Liu
    Citation: BMC Complementary and Alternative Medicine 2014 14:449
  10. Fever and pain management is a very challenging job for the clinician as the available synthetic agents are causing serious side effects. The present research article deals with the antipyretic and antinocicep...

    Authors: Abdur Rauf, Rehan Khan, Haroon Khan, Barkat Ullah and Samreen Pervez
    Citation: BMC Complementary and Alternative Medicine 2014 14:448
  11. Spinal cord injury (SCI)-induced secondary oxidative stress associates with a clinical complication and high mortality. Treatments to improve the neurological outcome of secondary injury are considered as impo...

    Authors: Chi-Long Juang, Fei Shish Yang, Ming Shuang Hsieh, Hu-Yi Tseng, Su-Chiu Chen and Hsiao-Chuan Wen
    Citation: BMC Complementary and Alternative Medicine 2014 14:447
  12. Malignant melanoma is a less common but highly dangerous form of skin cancer; it starts in the melanocytes cells found in the outer layer of the skin. Jararhagin toxin, a metalloproteinase isolated from Bothrops ...

    Authors: Durvanei Augusto Maria, Manuela Garcia Laveli da Silva, Mario Cesar Correia Junior and Itamar Romano Garcia Ruiz
    Citation: BMC Complementary and Alternative Medicine 2014 14:446
  13. Stress places a metabolic burden on homeostasis and is linked to heightened sympathetic activity, increased energy expenditure and pathology. The yogic state is a hypometabolic state that corresponds with mind...

    Authors: Anupama Tyagi, Marc Cohen, John Reece and Shirley Telles
    Citation: BMC Complementary and Alternative Medicine 2014 14:445
  14. Increased production of matrix metalloproteinases (MMPs) is closely related to the progression of osteoarthritis (OA). The present study was performed to investigate the potential value of biochanin A in inhib...

    Authors: Ding-Qian Wu, Hui-ming Zhong, Qian-hai Ding and Li Ba
    Citation: BMC Complementary and Alternative Medicine 2014 14:444
  15. ‘Kneipp Therapy’ (KT) is a form of Complementary and Alternative Medicine (CAM) that includes a combination of hydrotherapy, herbal medicine, mind-body medicine, physical activities, and healthy eating. Since ...

    Authors: Miriam Ortiz, Eva Soom Ammann, Corina Salis Gross, Katharina Schnabel, Torsten Walbaum, Sylvia Binting, Herbert Felix Fischer, Michael Teut, Jan Kottner, Ralf Suhr and Benno Brinkhaus
    Citation: BMC Complementary and Alternative Medicine 2014 14:443
  16. Vitamin C (VitC) has recently been shown to exert beneficial effects, including protecting organ function and inhibiting inflammation, in various critical care conditions, but the specific mechanism remains un...

    Authors: Bing Zhao, Jian Fei, Ying Chen, Yi-Lin Ying, Li Ma, Xiao-Qin Song, Jie Huang, Er-Zhen Chen and En-Qiang Mao
    Citation: BMC Complementary and Alternative Medicine 2014 14:442
  17. To investigate the effects and potential mechanism of electroacupuncture intervention on expressions of Angiotensin II and its receptors-mediated signaling pathway in experimentally induced cerebral ischemia.

    Authors: Jing Li, Jiaojun He, Yuanhao Du, Jingjun Cui, Ying Ma and Xuezhu Zhang
    Citation: BMC Complementary and Alternative Medicine 2014 14:441
  18. The potential benefits of earthworm (Pheretima aspergillum) for healing have received considerable attention recently. Osteoblast and osteoclast activities are very important in bone remodeling, which is crucial ...

    Authors: Yuan-Tsung Fu, Kuo-Yu Chen, Yueh-Sheng Chen and Chun-Hsu Yao
    Citation: BMC Complementary and Alternative Medicine 2014 14:440
  19. The increasing resistance of Candida yeasts towards antifungal compounds and the limited choice of therapeutic drugs have spurred great interest amongst the scientific community to search for alternative anti-Can...

    Authors: Sun-Tee Tay, Su-Lin Lim and Hui-Wee Tan
    Citation: BMC Complementary and Alternative Medicine 2014 14:439
  20. The widespread use of CAM around the world requires health professionals including pharmacists to have the required knowledge to better advise their patients. This has lead to an increased need for the inclusi...

    Authors: Peter B James and Abdulai J Bah
    Citation: BMC Complementary and Alternative Medicine 2014 14:438
  21. Traditional Korean medicine (TKM) is acknowledged to be prevalent among the Korean public, but few follow-up studies are available to confirm this commonly held belief. Whereas most survey studies have focused...

    Authors: Jong-Min Woo, Eun-Ji Park, Minhee Lee, Miyoung Ahn, Soohyun Kwon and Ki Hoon Koo
    Citation: BMC Complementary and Alternative Medicine 2014 14:436
  22. Diabetes complications include various symptoms such as diabetic neuropathy and cognitive disorders. Aldose reductase (AR) is the rate-limiting enzyme of the polyol pathway and is one of the causal factors of ...

    Authors: Toshihisa Onoda, Chikako Ishikawa, Takahiro Fukazawa, Wei Li, Masahiko Obayashi and Kazuo Koike
    Citation: BMC Complementary and Alternative Medicine 2014 14:435
  23. Ganoderma lucidum (G. lucidum, Reishimax) is an herbal mushroom known to have inhibitory effect on tumor cell growth. However, the molecular mechanisms responsible for its anti-proliferative effects on the ovari...

    Authors: Shuyan Dai, Jingjing Liu, Xiaofei Sun and Ning Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:434
  24. Celastrus orbiculatus has been used as a folk medicine in China for the treatment of many diseases. In the laboratory, the ethyl acetate extract of Celastrus orbiculatus (COE) displays a wide range of anticancer...

    Authors: Yaodong Zhu, Yanqing Liu, Yayun Qian, Xiaojun Dai, Ling Yang, Jue Chen, Shiyu Guo and Tadashi Hisamitsu
    Citation: BMC Complementary and Alternative Medicine 2014 14:433
  25. Maternal health is a public health priority in many African countries, but little is known about herbal medicine use in pregnancy. This study aimed to determine the pattern of use of herbal medicine in an urba...

    Authors: Mamothena Carol Mothupi
    Citation: BMC Complementary and Alternative Medicine 2014 14:432
  26. Diluted bee venom (BV) is known to have anti-nociceptive and anti-inflammatory effects. We therefore assessed whether perineural bee venom pretreatment could attenuate the development of neuropathic pain in th...

    Authors: Won Uk Koh, Seong Soo Choi, Jong Hyuk Lee, So Hee Lee, Sun Kyung Lee, Yoon Kyung Lee, Jeong Gil Leem, Jun Gol Song and Jin Woo Shin
    Citation: BMC Complementary and Alternative Medicine 2014 14:431
  27. Compared with the traditional oral administration form, injection administration is basically superior in terms of both biological availability and therapeutic effects. However, few researches have focused on ...

    Authors: Haixing Yang, Wenjuan Zhang, Chao Huang, Wei Zhou, Yao Yao, Zhenzhong Wang, Yan Li, Wei Xiao and Yonghua Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:430
  28. Recently, we have highlighted the immunomodulatory activity of the standardized extracts of Phyllanthus amarus and P. urinaria. The present study was carried out to correlate between the prevalent constituents of...

    Authors: Ibrahim Jantan, Menaga Ilangkovan, Yuandani and Hazni Falina Mohamad
    Citation: BMC Complementary and Alternative Medicine 2014 14:429
  29. Dendropanax morbifera Léveille is used in herbal medicine as a cancer treatment. In this study, we investigated the effects of Dendropanax morbifera stem extract (DMS) on cadmium (Cd) excretion from the blood an...

    Authors: Woosuk Kim, Dae Won Kim, Dae Young Yoo, Hyo Young Jung, Sung Min Nam, Jong Whi Kim, Soon-Min Hong, Dong-Woo Kim, Jung Hoon Choi, Seung Myung Moon, Yeo Sung Yoon and In Koo Hwang
    Citation: BMC Complementary and Alternative Medicine 2014 14:428
  30. Previous data indicate that purified components of ginseng can inhibit HIV reverse transcriptase in vitro, suggesting that ginseng components in plasma may interfere with HIV-1 RNA detection assays.

    Authors: Rahul P Bakshi, Todd T Brown, Antoine Simmons, Chun-Su Yuan, Brent A Bauer, Jeff A Sloan and Adriana Andrade
    Citation: BMC Complementary and Alternative Medicine 2014 14:427
  31. This study evaluated the impact of Vernonia amygdalina (VA) on the transcription of key enzymes involved in cellular modulation of glucose in streptozotocin-induced diabetic rats in a bid to understand the possib...

    Authors: Item Justin Atangwho, Khoo Boon Yin, Muhammad Ihtisham Umar, Mariam Ahmad and Mohd Zaini Asmawi
    Citation: BMC Complementary and Alternative Medicine 2014 14:426
  32. The inclusion of prayer-for-health (PFH) in the definition of complementary alternative medicine (CAM) has resulted in higher levels of CAM use. The objective of this study was to assess PFH and CAM use among ...

    Authors: Ping Lei Chui, Khatijah Lim Abdullah, Li Ping Wong and Nur Aishah Taib
    Citation: BMC Complementary and Alternative Medicine 2014 14:425
  33. The fermented leaves and stems of Cyclopia intermedia are used to brew honeybush tea, an herbal tea indigenous to South Africa with reported anti-wrinkle effects. Wrinkle formation caused by photoaging clearly in...

    Authors: A-Rang Im, Jae Hyoung Song, Mi Young Lee, Sung Hum Yeon, Key An Um and Sungwook Chae
    Citation: BMC Complementary and Alternative Medicine 2014 14:424
  34. Functional constipation (FC) is a common functional gastrointestinal disorders (FGIDs) which has a major impact on the quality of life. Acupuncture is widely used as an alternative and complementary medicine (...

    Authors: XiaoHu Xu, CuiHong Zheng, MingMin Zhang, Wei Wang and GuangYing Huang
    Citation: BMC Complementary and Alternative Medicine 2014 14:423
  35. Castanea mollissima Blume (Chinese chestnut), as a food product is known for its various nutrients and functional values to the human health. The present study was carried out to analyze the anti-diabetic compli...

    Authors: Lin Zhang, Hui-yuan Gao, Masaki Baba, Yoshihito Okada, Toru Okuyama, Li-jun Wu and Li-bin Zhan
    Citation: BMC Complementary and Alternative Medicine 2014 14:422
  36. Anisochilus carnosus (L.f.) wall (Lamiaceae), an annual herb which grows at high altitude is used extensively in folk medicine for the treatment of ailments such as gastric ulcer and skin diseases. The aim of ou...

    Authors: Jaykumar Bhagat, Richard Lobo, Nimmy Kumar, Jessy Elizabeth Mathew and Aravinda Pai
    Citation: BMC Complementary and Alternative Medicine 2014 14:421
  37. Though herbal medicines have been used for cancer prevention and treatment, their scientific evidences still remain unclear so far. Thus, complementary and alternative medicine (CAM) project has been actively ...

    Authors: Bo Geun Kim, Hee Young Kwon, Eun Jung Sohn, Sungmin Hwang, Oh sung Kwon and Sung-Hoon Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:420
  38. Osteopontin (OPN) is one of important molecular targets in cancer progression, metastasis as a calcium-binding, extracellular-matrix-associated protein of the small integrin-binding ligand and, N-linked glycop...

    Authors: Tae-kyung Kwak, Eun Jung Sohn, Sunhee Kim, Gunho Won, Jeong-Un Choi, Kwon Jeong, Myoungseok Jeong, Oh Sung Kwon and Sung-Hoon Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:419
  39. Diwu Yanggan (DWYG) is a Chinese compound herbal preparation which consists of five Chinese herbs. This study investigates the preventative effects of DWYG on liver fibrosis induced by carbon tetrachloride (CCl4)...

    Authors: Xin Shen, Sisi Cheng, Yu Peng, Hongli Song and Hanmin Li
    Citation: BMC Complementary and Alternative Medicine 2014 14:418
  40. Sensory isolation in a flotation tank is a method known for inducing deep relaxation and subsequent positive health effects for patients suffering from e.g. stress or muscle tensions pains. Very few studies ha...

    Authors: Anette Kjellgren and Jessica Westman
    Citation: BMC Complementary and Alternative Medicine 2014 14:417
  41. Reducing exposure to toxic environmental agents is a critical area of intervention. Prenatal or postnatal exposure to certain chemicals has been documented to increase the risk of autism spectrum disorder. Pro...

    Authors: Hanan A Alfawaz, Ramesa Shafi Bhat, Laila Al-Ayadhi and Afaf K El-Ansary
    Citation: BMC Complementary and Alternative Medicine 2014 14:416
  42. Ginsenosides, the major bioactive compounds in ginseng root, have been found to have antioxidant, immunomodulatory and anti-inflammatory activities. This study investigated the effects of ginsenosides on carbo...

    Authors: Ya-Ling Hou, Ya-Hui Tsai, Yun-Ho Lin and Jane C-J Chao
    Citation: BMC Complementary and Alternative Medicine 2014 14:415
  43. Musculoskeletal disorders, stress and performance anxiety are common in musicians. Therefore, some use the Alexander Technique (AT), a psycho-physical method that helps to release unnecessary muscle tension an...

    Authors: Sabine D Klein, Claudine Bayard and Ursula Wolf
    Citation: BMC Complementary and Alternative Medicine 2014 14:414
  44. Dioscoreanone (DN) isolated from Dioscorea membranacea Pierre has been reported to exert potent cytotoxic effects against particular types of cancer. The present study was carried out to investigate the cytotoxic...

    Authors: Pintusorn Hansakul, Kalaya Aree, Sermkiat Tanuchit and Arunporn Itharat
    Citation: BMC Complementary and Alternative Medicine 2014 14:413
  45. Colorectal cancer has become one of the leading cause of cancer morbidity and mortality throughout world. Hederagenin, a derivative of oleanolic acid isolated from the leaves of ivy (Hedera helix L.), has been...

    Authors: Bao-Xin-Zi Liu, Jin-Yong Zhou, Yu Li, Xi Zou, Jian Wu, Jun-Fei Gu, Jia-Rui Yuan, Bing-Jie Zhao, Liang Feng, Xiao-Bin Jia and Rui-Ping Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:412
  46. Negative affective states such as anxiety, depression and stress are significant risk factors for cardiovascular disease, particularly in cardiac and post-cardiac rehabilitation populations.

    Authors: Alan Yeung, Hosen Kiat, A Robert Denniss, Birinder S Cheema, Alan Bensoussan, Bianca Machliss, Ben Colagiuri and Dennis Chang
    Citation: BMC Complementary and Alternative Medicine 2014 14:411
  47. There is a lack of research on the organisational operations of integrative healthcare (IHC) practices. IHC is a therapeutic strategy integrating conventional and complementary medicine in a shared context to ...

    Authors: Suzanne J Grant and Alan Bensoussan
    Citation: BMC Complementary and Alternative Medicine 2014 14:410
  48. Alkaloids present in plants of the Amaryllidaceae family are secondary metabolites of high biological interest, possessing a wide range of pharmacological activities. In the search for new plant-derived compou...

    Authors: Francesca Bonvicini, Fabiana Antognoni, Carmelina Iannello, Andrea Maxia, Ferruccio Poli and Giovanna Angela Gentilomi
    Citation: BMC Complementary and Alternative Medicine 2014 14:409
  49. Ginger leaf (GL) has long been used as a vegetable, tea and herbal medicine. However, its pharmacological properties are still poorly understood. Thus, we performed in vitro studies to evaluate anti-cancer proper...

    Authors: Gwang Hun Park, Jae Ho Park, Hun Min Song, Hyun Ji Eo, Mi Kyoung Kim, Jin Wook Lee, Man Hyo Lee, Kiu-Hyung Cho, Jeong Rak Lee, Hyeon Je Cho and Jin Boo Jeong
    Citation: BMC Complementary and Alternative Medicine 2014 14:408