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  1. Complementary therapies (CT), such as relaxation technique, massage, guided imagery, and accupuncture have shown to benefit patients undergoing surgery. The aim of this study was to determine the feasibility o...

    Authors: Margaret M Hansen
    Citation: BMC Complementary and Alternative Medicine 2015 15:92
    Content type: Research article Published on:

  2. Intracerebral hemorrhage (ICH) is a fatal subtype of stroke that lacks effective treatments. Angiogenesis following ICH is an important response mediating brain recovery and repair. Phosphorylation of vascular...

    Authors: Han-Jin Cui, A-Li Yang, Hua-Jun Zhou, Cong Wang, Jie-Kun Luo, Yuan Lin, Yan-Xia Zong and Tao Tang
    Citation: BMC Complementary and Alternative Medicine 2015 15:91
    Content type: Research article Published on:

  4. Red yeast rice (RYR) is a fermented product used as a food supplement to promote blood circulation and lower blood cholesterol levels in eastern Asia. Interestingly, monacolin K is the most active compound in ...

    Authors: Anurak Bunnoy, Kanokporn Saenphet, Saisamorn Lumyong, Supap Saenphet and Siriwadee Chomdej
    Citation: BMC Complementary and Alternative Medicine 2015 15:88
    Content type: Research article Published on:

  5. The hypothalamus is an essential part of the brain that responds to a variety of signaling including stressful stimulations and acupuncture signals. It is also the key element of the hypothalamic-pituitary-adr...

    Authors: Shao-jun Wang, Jiao-jiao Zhang, Hao-yan Yang, Fang Wang and Si-ting Li
    Citation: BMC Complementary and Alternative Medicine 2015 15:87
    Content type: Research article Published on:

  6. Menopause is a natural phase in a woman’s aging process, characterized by the cessation of menstruation. Women who are going through the menopause transition can experience physiological symptoms that signific...

    Authors: Jennifer Croden, Sue Ross, Nese Yuksel and Beate C Sydora
    Citation: BMC Complementary and Alternative Medicine 2015 15:86
    Content type: Research article Published on:

  7. Previous research suggests benefits of yoga in reducing depression and anxiety. However, common concerns in reviews of the research include lack of detail, rationale and consistency of approach of intervention...

    Authors: Michael de Manincor, Alan Bensoussan, Caroline Smith, Paul Fahey and Suzanne Bourchier
    Citation: BMC Complementary and Alternative Medicine 2015 15:85
    Content type: Research article Published on:

  8. Nowadays plant derived natural compounds have gained huge amount of research attention especially in food and medicine industries due to their multitude of biological and therapeutic properties as alternative ...

    Authors: Vivek K Bajpai, Yong-Ha Park, MinKyun Na and Sun Chul Kang
    Citation: BMC Complementary and Alternative Medicine 2015 15:84
    Content type: Research article Published on:

  9. Mangifera pajang Kosterm is a plant species from the mango family (Anacardiaceae). The fruits are edible and have been reported to have high antioxidant content. However, the detailed phytochemical studies of the...

    Authors: Sadikah Ahmad, Mohd Aspollah Sukari, Nurussaadah Ismail, Intan Safinar Ismail, Ahmad Bustamam Abdul, Mohd Fadzelly Abu Bakar, Nurolaini Kifli and Gwendoline C L Ee
    Citation: BMC Complementary and Alternative Medicine 2015 15:83
    Content type: Research article Published on:

  10. Trypanosomiasis is a neglected tropical disease with complex clinical manifestations, tedious diagnosis, and difficult treatments. The drugs available for the treatment of this endemic disease are old, expensi...

    Authors: Ngozi Nwodo, Festus Okoye, Daowan Lai, Abdesammed Debbab, Marcel Kaiser, Reto Brun and Peter Proksch
    Citation: BMC Complementary and Alternative Medicine 2015 15:82
    Content type: Research article Published on:

  11. Qian Yang Yu Yin Granule (QYYYG), a traditional Chinese herbal medicine, has been indicated for renal damage in hypertension for decades in China, but little remains known regarding its underlying molecular me...

    Authors: Kang Ding, Yan Wang, Weimin Jiang, Yu Zhang, Hongping Yin and Zhuyuan Fang
    Citation: BMC Complementary and Alternative Medicine 2015 15:81
    Content type: Research article Published on:

  12. Complementary and alternative herbal medicines are recently considered as a promising approach for treating various diseases. We screened approximately 100 plant extracts for anti-allergic activity. Rhamnus davur...

    Authors: Ji Hyung Kim, A-Ram Kim, Hyuk Soon Kim, Hyun Woo Kim, Young Hwan Park, Jueng Soo You, Yeong Min Park, Erk Her, Hyung Sik Kim, Young Mi Kim and Wahn Soo Choi
    Citation: BMC Complementary and Alternative Medicine 2015 15:80
    Content type: Research article Published on:

  13. Formation of biofilm is known to enhance the virulence of methicillin-resistance Staphylococcus aureus (MRSA), which is associated with persistent infections in hospital settings. The biofilm layer essentially fo...

    Authors: Carolina Santiago, Kuan-Hon Lim, Hwei-San Loh and Kang Nee Ting
    Citation: BMC Complementary and Alternative Medicine 2015 15:79
    Content type: Research article Published on:

  14. Low-level lasers working at 633 or 670 nm and emitting extremely low power densities (Ultra Low Level Lasers - ULLL) exert an overall effect of photobiostimulation on cellular metabolism and energy balance. In...

    Authors: Alessandro Giuliani, Luca Lorenzini, Marco Alessandri, Roberta Torricella, Vito Antonio Baldassarro, Luciana Giardino and Laura Calzà
    Citation: BMC Complementary and Alternative Medicine 2015 15:78
    Content type: Research article Published on:

  15. The aim of this study was to investigate the regulative activity of (5R)-5-hydroxytriptolide (LLDT-8) on receptor activator of nuclear factor κ-B ligand (RANKL)/receptor activator of nuclear factor κ-B (RANK)/...

    Authors: Yi Shen, Ting Jiang, Rongsheng Wang, Shijun He, Mengru Guo, Jianping Zuo and Dongyi He
    Citation: BMC Complementary and Alternative Medicine 2015 15:77
    Content type: Research article Published on:

  16. The prevalence and severity of obesity and associated co-morbidities are rapidly increasing across the world. Natural products-based drug intervention has been proposed as one of the crucial strategies for man...

    Authors: Ramgopal Mopuri, Muniswamy Ganjayi, Kruthika S Banavathy, Brahma Naidu Parim and Balaji Meriga
    Citation: BMC Complementary and Alternative Medicine 2015 15:76
    Content type: Research article Published on:

  17. Matricaria chamomilla commonly known as “Chamomile” (Asteraceae) is a popular medicinal herb widely used in indigenous system of medicine for a variety of ailments. However, there is no detailed study available s...

    Authors: Malik Hassan Mehmood, Siraj Munir, Uzair Ali Khalid, Mudassir Asrar and Anwarul Hassan Gilani
    Citation: BMC Complementary and Alternative Medicine 2015 15:75
    Content type: Research article Published on:

  18. The fruit of Cyrtocarpa procera is used to treat stomach diseases by people living in San Rafael, Coxcatlan, Puebla. This work investigated the antibacterial, antioxidant, cytotoxic and anti-inflammatory activiti...

    Authors: Karla Stephanie Martinez-Elizalde, Manuel Jimenez-Estrada, Cesar Mateo Flores, Luis Barbo Hernandez, Rocio Rosas-Lopez, Angel Duran-Diaz, Oscar J Nieto-Yañez, Elizabeth Barbosa, Marco Aurelio Rodriguez-Monroy and Margarita Canales-Martinez
    Citation: BMC Complementary and Alternative Medicine 2015 15:74
    Content type: Research article Published on:

  19. Management of diabetes without any side effects is still a challenge to the medical system. This leads to increasing demand for natural products with antidiabetic activity with fewer side effects. Grewia hirsuta ...

    Authors: Abirami Natarajan, Shobana Sugumar, Sivakumar Bitragunta and Natarajan Balasubramanyan
    Citation: BMC Complementary and Alternative Medicine 2015 15:73
    Content type: Research article Published on:

  20. Short-term vasodilatation in the pain area after dry needling (DN) of active trigger points (TrPs) was recorded in several cases of sciatica. Moreover, the presence of TrPs in sciatica patients secondary to pr...

    Authors: Elżbieta Skorupska, Michał Rychlik and Włodzimierz Samborski
    Citation: BMC Complementary and Alternative Medicine 2015 15:72
    Content type: Research article Published on:

  21. An emerging paradigm suggests children with autism display a unique pattern of environmental, genetic, and epigenetic triggers that make them susceptible to developing dysfunctional heavy metal and chemical de...

    Authors: Scott Faber, Gregory M Zinn, Andrew Boggess, Timothy Fahrenholz, John C Kern II and HM Skip Kingston
    Citation: BMC Complementary and Alternative Medicine 2015 15:71
    Content type: Research article Published on:

  22. The antinociceptive effect of an aqueous extract from the leaves of Toona sinensis (TS, [A. Juss., M. Roem.]) was studied using the writhing test in mice.

    Authors: Yu-feng Su, Yu-Chiao Yang, Hseng-Kuang Hsu, Shiuh-Lin Hwang, Kung-Shing Lee, Ann-Shung Lieu, Te-Fu Chan and Chih-Lung Lin
    Citation: BMC Complementary and Alternative Medicine 2015 15:70
    Content type: Research article Published on:

  23. Our preliminary studies indicated that electroacupuncture (EA) at the ST36 and Ashi acupoints could promote regeneration of the rabbit gastrocnemius (GM) by improving microcirculation perfusion, promoting the ...

    Authors: Shouyao Liu, Rongguo Wang, Dan Luo, Qianwei Xu, Cheng Xiao, Peng Lin, Zhange Yu, Xuanji Zhao, Rongrong Cai, Jinhui Ma, Qingxi Zhang and Yunting Wang
    Citation: BMC Complementary and Alternative Medicine 2015 15:69
    Content type: Research article Published on:

  24. Biofilm formation is important in Candida albicans pathogenesis and constitutes a mechanism of antifungal resistance. Thus, we evaluated the effect of proanthocyanidins polymer-rich fractions from Stryphnodendron...

    Authors: Raul Leal Faria Luiz, Taissa Vieira Machado Vila, João Carlos Palazzo de Mello, Celso Vataru Nakamura, Sonia Rozental and Kelly Ishida
    Citation: BMC Complementary and Alternative Medicine 2015 15:68
    Content type: Research article Published on:

  25. Plants are traditionally used for medicinal treatment of numerous human disorders including infectious diseases caused by microorganisms. Due to the increasing resistance of many pathogens to commonly used ant...

    Authors: Ahmed Rezk, Jennifer Nolzen, Hartwig Schepker, Dirk C Albach, Klaudia Brix and Matthias S Ullrich
    Citation: BMC Complementary and Alternative Medicine 2015 15:67
    Content type: Research article Published on:

  26. Tang Bi Kang (TBK) is a traditional Chinese medicine granule. It has been shown to have effects on nerve conduction velocity deficits, blood-related factors and oxidative stress. This study was undertaken to e...

    Authors: Xin-Wei Yang, Feng-Qi Liu, Jing-Jing Guo, Wei-Jie Yao, Qing-Qin Li, Tong-Hua Liu and Li-Ping Xu
    Citation: BMC Complementary and Alternative Medicine 2015 15:66
    Content type: Research article Published on:

  27. Breast cancer-related mortality increases annually. The efficacy of current breast cancer treatments is limited, and they have numerous side effects and permit high recurrence. Patients with estrogen receptor ...

    Authors: Ren-Jun Hsu, Yao-Chin Hsu, Shu-Pin Chen, Chia-Lynn Fu, Jyh-Cherng Yu, Fung-Wei Chang, Ying-Hsin Chen, Jui-Ming Liu, Jar-Yi Ho and Cheng-Ping Yu
    Citation: BMC Complementary and Alternative Medicine 2015 15:65
    Content type: Research article Published on:

  28. To determine the antiproliferative effect of gamma-tocotrienol (GTT) treatment on differential protein expression in HepG2 cells.

    Authors: Farahani Abdul Rahman Sazli, Zakiah Jubri, Mariati Abdul Rahman, Saiful Anuar Karsani, Abdul Gapor Md Top and Wan Zurinah Wan Ngah
    Citation: BMC Complementary and Alternative Medicine 2015 15:64
    Content type: Research article Published on:

  29. Persicaria hydropiper (Linn.) Delarbre is a common plant of Polygonaceae family commonly called Bishkatali in Bangladesh. Leaves of the plant are traditionally used in the treatment of rheumatic pain, gout, and s...

    Authors: Ambia Khatun, Mohammad Zafar Imam and Md Sohel Rana
    Citation: BMC Complementary and Alternative Medicine 2015 15:63
    Content type: Research article Published on:

  30. Ghritas are ayurvedic lipid based preparations in which oil or ghee is boiled with prescribed kasaya (polyherbal decoction) and kalka (fine paste of herbs) until the evaporation of aqueous phase transfers the ...

    Authors: Selvakumar Duraipandi, Vijaya Selvakumar and Ng Yun Er
    Citation: BMC Complementary and Alternative Medicine 2015 15:62
    Content type: Research article Published on:

  31. Homocysteine and pro-inflammatory mediators such as cyclooxygenase-2 (COX-2) have been linked to vascular dysfunction and risks of cardiovascular diseases. Fulvic acid (FA), a class of compounds of humic subst...

    Authors: Shao-Ju Chien, Te-Chuan Chen, Hsing-Chun Kuo, Cheng-Nan Chen and Shun-Fu Chang
    Citation: BMC Complementary and Alternative Medicine 2015 15:61
    Content type: Research article Published on:

  32. T helper (Th) 17 and regulatory T (Treg) cells play a critical role in the pathogenesis of multiple sclerosis (MS) disease. Bu Shen Yi Sui Capsule (BSYSC), a traditional Chinese medicine formula, has been used...

    Authors: Qi Zheng, Tao Yang, Ling Fang, Lei Liu, Haolong Liu, Hui Zhao, Yiyi Zhao, Hongzhu Guo, Yongping Fan and Lei Wang
    Citation: BMC Complementary and Alternative Medicine 2015 15:60
    Content type: Research article Published on:

  33. To determine the effect of flavonoids in conjunction with antibiotics in methicillin resistant Staphylococcus aureus (MRSA) a study was designed. The flavonoids included Rutin, Morin, Qurecetin while antibiotics ...

    Authors: Muhammad Usman Amin, Muhammad Khurram, Baharullah Khattak and Jafar Khan
    Citation: BMC Complementary and Alternative Medicine 2015 15:59
    Content type: Research article Published on:

  34. Post-menopausal osteoporosis has long been treated and prevented by estrogen replacement therapy (ERT). Despite its effectiveness, ERT is associated with serious adverse effects. Labisia pumila var. alata (LP) is...

    Authors: Nadia Mohd Effendy, Shahrum Abdullah, Mohd Faridz Mod Yunoh and Ahmad Nazrun Shuid
    Citation: BMC Complementary and Alternative Medicine 2015 15:58
    Content type: Research article Published on:

  35. To search for new sources of safe and inexpensive antioxidant agents which can be used to treat various oxidative stress - related diseases, the phenolic contents of leaf of Tetracarpidium conophorum were charact...

    Authors: Seun F Akomolafe, Ganiyu Oboh, Afolabi A Akindahunsi and Anthony J Afolayan
    Citation: BMC Complementary and Alternative Medicine 2015 15:57
    Content type: Research article Published on:

  36. An andrographolide analogue, 3, 19-isopropylideneandrographolide (IPAD), exerts an inhibitory effect on replication of wild-type herpes simplex virus serotype 1 (HSV-1). In this study, we examined the anti-vir...

    Authors: Thongkoon Priengprom, Tipaya Ekalaksananan, Bunkerd Kongyingyoes, Supawadee Suebsasana, Chantana Aromdee and Chamsai Pientong
    Citation: BMC Complementary and Alternative Medicine 2015 15:56
    Content type: Research article Published on:

  37. Tong Luo Jiu Nao (TLJN), a modern formula of Chinese medicine extracts on the basis of Traditional Chinese Medicine theory, has been used to treat dementia. The present study aimed to investigate its ameliorat...

    Authors: Zhe Shi, Cong Lu, Xiuping Sun, Qiong Wang, Shanguang Chen, Yinghui Li, Lina Qu, Lingling Chen, Lanlan Bu, Duanfang Liao and Xinmin Liu
    Citation: BMC Complementary and Alternative Medicine 2015 15:55
    Content type: Research article Published on:

  38. The National Health and Morbidity Survey in 2011 estimated that 35.1% (5.7 million) of Malaysian adults aged 18 and older suffer from hypertension. Hypertension is still treated by conventional medicine despit...

    Authors: Maizura Mohd Zainudin, Zaiton Zakaria and Nor Anita Megat Mohd Nordin
    Citation: BMC Complementary and Alternative Medicine 2015 15:54
    Content type: Research article Published on:

  39. Zulu people living in the rural area of Maputaland (KwaZulu-Natal, South Africa) rely heavily on medicinal plants for the treatment of diarrhoea. Abundant availability of medicinal plants in the study area off...

    Authors: Sandy F van Vuuren, Mduduzi N Nkwanyana and Helene de Wet
    Citation: BMC Complementary and Alternative Medicine 2015 15:53
    Content type: Research article Published on:

  40. Metabolic syndrome (MetS) comprises a spectrum of clinical phenotypes in which dyslipidemia, dysglycemia and hypertension are clustered and where all share a high level of oxidative stress and an increased ris...

    Authors: Veronique Verhoeven, Anastasia Van der Auwera, Luc Van Gaal, Roy Remmen, Sandra Apers, Michel Stalpaert, Johan Wens and Nina Hermans
    Citation: BMC Complementary and Alternative Medicine 2015 15:52
    Content type: Research article Published on:

  41. Bufei Jianpi granules has been confirmed effective in improving pulmonary function, alleviating acute exacerbations, improving six-minute walk distance and quality of life, and benefited in 12-month follow-up ...

    Authors: Yuqiong Dong, Ya Li, Yafei Sun, Jing Mao, Fengjia Yao, Yange Tian, Lili Wang, Linlin Li, Suyun Li and Jiansheng Li
    Citation: BMC Complementary and Alternative Medicine 2015 15:51
    Content type: Research article Published on:

  42. Nardostachys jatamansi DC is a Himalayan medicinal herb that has been described in various traditional systems of medicine for its use in cancer. In view of its traditional claims, and chemical constituents, anti...

    Authors: Shilpee Chaudhary, Kodangala Subraya Chandrashekar, Karkala Sreedhara Ranganath Pai, Manganahalli Manjunath Setty, Raviraj Anand Devkar, Neetinkumar Dnyanoba Reddy and Muhammed Haneefa Shoja
    Citation: BMC Complementary and Alternative Medicine 2015 15:50
    Content type: Research article Published on:

  43. The use of complementary and alternative medicine (CAM) is widespread among children in Germany and other European countries. Only a few studies are available on trends in pediatric CAM use over time. The stud...

    Authors: Salvatore Italia, Helmut Brand, Joachim Heinrich, Dietrich Berdel, Andrea von Berg and Silke Britta Wolfenstetter
    Citation: BMC Complementary and Alternative Medicine 2015 15:49
    Content type: Research article Published on:

  44. Solobacterium moorei is a volatile sulfide compound (VSC)-producing Gram-positive anaerobic bacterium that has been associated with halitosis. The aim of this study was to investigate the effects of green tea ext...

    Authors: Marie-Pierre Morin, Telma Blanca Lombardo Bedran, Jade Fournier-Larente, Bruno Haas, Jabrane Azelmat and Daniel Grenier
    Citation: BMC Complementary and Alternative Medicine 2015 15:48
    Content type: Research article Published on:

  45. Samsoeum has long been used in Korea and other Asian countries as a traditional medicine to treat various diseases. In the present study, we investigated the antiasthma effect of the herbal medicine Samsoeum w...

    Authors: Woo-Young Jeon, In-Sik Shin, Hyeun-Kyoo Shin and Mee-Young Lee
    Citation: BMC Complementary and Alternative Medicine 2015 15:47
    Content type: Research article Published on:

  46. Biobanks are more important in medical area because they can give researchers data for demonstrating and validating their research. In this study, we developed a biobank called the Korea Constitutional Multice...

    Authors: Hee-Jeong Jin, Younghwa Baek, Ho-Seok Kim, Jonghyang Ryu and Siwoo Lee
    Citation: BMC Complementary and Alternative Medicine 2015 15:46
    Content type: Research article Published on:

  47. In this study, the effect of mango kernel extract in the induction of apoptosis of the breast cancer (MDA-MB-231) cell line was examined. This is an attempt to discover alternatives to current therapeutic regi...

    Authors: Al-Shwyeh Hussah Abdullah, Abdulkarim Sabo Mohammed, Abdullah Rasedee, Mohamed Elwathig Saeed Mirghani and Mothanna Sadiq Al-Qubaisi
    Citation: BMC Complementary and Alternative Medicine 2015 15:45
    Content type: Research article Published on:

  48. The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barter...

    Authors: Serge Secco Atsafack, Jules-Roger Kuiate, Raymond Simplice Mouokeu, Martin Luther Koanga Mogtomo, Alembert Tiabou Tchinda, Tamokou Jean De Dieu, Huguette Magnifouet Nana, Rébecca Madeleine Ebelle Etame, Lucie Biyiti and Rosalie Annie Ngono Ngane
    Citation: BMC Complementary and Alternative Medicine 2015 15:44
    Content type: Research article Published on:

  49. Psychological stressors may cause affective disorders, such as depression and anxiety, by altering expressions of corticotropin releasing factor (CRF), serotonin (5-HT), and tyrosine hydroxylase (TH) in the br...

    Authors: Hyun-Jung Park, Eun-Ju Lim, Rong Jie Zhao, Sa Rang Oh, Ji Wook Jung, Eun-Mi Ahn, Eun Sook Lee, Jin Suk Koo, Hee Young Kim, Suchan Chang, Hyun Soo Shim, Kwang Joong Kim, Young Seob Gwak and Chae Ha Yang
    Citation: BMC Complementary and Alternative Medicine 2015 15:43
    Content type: Research article Published on:

  50. Inverse docking technology has been a trend of drug discovery, and bioinformatics approaches have been used to predict target proteins, biological activities, signal pathways and molecular regulating networks ...

    Authors: Lianhong Yin, Lingli Zheng, Lina Xu, Deshi Dong, Xu Han, Yan Qi, Yanyan Zhao, Youwei Xu and Jinyong Peng
    Citation: BMC Complementary and Alternative Medicine 2015 15:41
    Content type: Research article Published on:
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ISSN: 2662-7671

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