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  1. Sesamol, a component of sesame seed oil, exhibited significant antioxidant activity in a battery of in vitro and ex vivo tests including lipid peroxidation induced in rat liver homogenates. Latter established its...

    Authors: Neha Singh, Neeraj Khullar, Vandita Kakkar and Indu Pal Kaur
    Citation: BMC Complementary and Alternative Medicine 2015 15:142
  2. Complementary and alternative medicine (CAM) use has steadily increased globally over the past two decades and is increasingly playing a role in the healthcare system in the United States. CAM practice-based e...

    Authors: Lysbeth Floden, Amy Howerter, Eva Matthews, Mark Nichter, James K Cunningham, Cheryl Ritenbaugh, Judith S Gordon and Myra L Muramoto
    Citation: BMC Complementary and Alternative Medicine 2015 15:140
  3. Angina pectoris (Angina) is a medical condition related to myocardial ischemia. Although acupuncture has been widely accepted as a clinical approach for angina, there is no sufficient evidence of its effective...

    Authors: Ning Wang, Sheng-Feng Lu, Hui Chen, Jian-Fei Wang, Shu-Ping Fu, Chen-Jun Hu, Yi Yang, Fan-Rong Liang and Bing-Mei Zhu
    Citation: BMC Complementary and Alternative Medicine 2015 15:139
  4. Diabetes mellitus is a global health problem and constantly increasing day by day. The number of diabetic people in world is expected to rise to 366 million in 2030. The available drugs for diabetes, insulin o...

    Authors: Md Ashraf Ali, Mir Imam Ibne Wahed, Naznin Ara Khatune, Bytul Mokaddesur Rahman, Ranjan Kumar Barman and Md Rafiqul Islam
    Citation: BMC Complementary and Alternative Medicine 2015 15:138
  5. Parkinson’s disease (PD) is the second most common neurodegenerative disease, affecting 2% of the population aged over 65 years old. Mitochondrial defects and oxidative stress actively participate in degenerat...

    Authors: Xi-Lin Lu, Yue-Hao Lin, Qi Wu, Feng-Juan Su, Cheng-Hui Ye, Lei Shi, Bai-Xuan He, Fei-Wen Huang, Zhong Pei and Xiao-Li Yao
    Citation: BMC Complementary and Alternative Medicine 2015 15:137
  6. Inflammation and pain underlies several pathological conditions. Synthetic drugs used for the management of these conditions carry severe toxic effects. Globally efforts are ongoing to introduce novel medicina...

    Authors: Tayyaba Afsar, Muhammad Rashid Khan, Suhail Razak, Shafi Ullah and Bushra Mirza
    Citation: BMC Complementary and Alternative Medicine 2015 15:136
  7. Melastoma malabathricum L. (Melastomaceae) is a small shrub with various medicinal uses. The present study was carried out to determine the gastroprotective mechanisms of methanol extract of M. malabathricum leav...

    Authors: Zainul Amiruddin Zakaria, Tavamani Balan, Siti Syariah Mamat, Norhafizah Mohtarrudin, Teh Lay Kek and Mohd Zaki Salleh
    Citation: BMC Complementary and Alternative Medicine 2015 15:135
  8. Naturally occurring flavonoids have been reported to possess various pharmacological properties. The aim of this study was to evaluate the antimicrobial and antioxidant activities of the MeOH extract and flavo...

    Authors: Marie Geneviève Djouossi, Jean-de-Dieu Tamokou, David Ngnokam, Jules-Roger Kuiate, Leon Azefack Tapondjou, Dominique Harakat and Laurence Voutquenne-Nazabadioko
    Citation: BMC Complementary and Alternative Medicine 2015 15:134
  9. Decreased cognition is recognized as one of the most severe and consistent behavioral impairments in dementia. Experimental studies have reported that acupuncture may improve cognitive deficits, relieve vascul...

    Authors: Fang Li, Chao-Qun Yan, Li-Ting Lin, Hui Li, Xiang-Hong Zeng, Yi Liu, Si-Qi Du, Wen Zhu and Cun-Zhi Liu
    Citation: BMC Complementary and Alternative Medicine 2015 15:133
  10. Psychological distress is associated with impaired health-related quality of life (HRQL) and poor sense of coherence (SOC). In a previous study, we found that therapeutic acupuncture (TA) and an integrative tr...

    Authors: Tina Arvidsdotter, Bertil Marklund, Charles Taft and Sven Kylén
    Citation: BMC Complementary and Alternative Medicine 2015 15:132
  11. Karapxa decoction (KD) is a Traditional Uighur Medicine used for hepatitis, cholecystitis, gastralgia, oedema, gout and arthralgia. Because of its purported effect in gout, its effects were tested in hyperuric...

    Authors: Nurmuhammat Amat, Anwar Umar, Parida Hoxur, Mihrigul Anaydulla, Guzalnur Imam, Ranagul Aziz, Halmurat Upur, Anake Kijjoa and Nicholas Moore
    Citation: BMC Complementary and Alternative Medicine 2015 15:131
  12. Macrophages are highly versatile cells that play an important role in tumour microenvironment. Tumour associated macrophages (TAMs) have been linked to both, good or bad prognosis of several cancer types depen...

    Authors: Myriam Estko, Stephan Baumgartner, Konrad Urech, Matthias Kunz, Ursula Regueiro, Peter Heusser and Ulrike Weissenstein
    Citation: BMC Complementary and Alternative Medicine 2015 15:130
  13. Chinese medicine is commonly used and covered by health insurance to treat symptoms of uterine fibroids in Taiwan. This retrospective cohort study compared the consumption of conventional western medicine and ...

    Authors: Shan-Yu Su, Chih-Hsin Muo and Donald E Morisky
    Citation: BMC Complementary and Alternative Medicine 2015 15:129
  14. The increasingly high incidence of ischemic stroke caused by thrombosis of the arterial vessels is one of the major factors that threaten people’s health and lives in the world. The present treatments for thro...

    Authors: Talha Bin Emran, Md Atiar Rahman, Mir Muhammad Nasir Uddin, Md Mominur Rahman, Md Zia Uddin, Raju Dash and Chadny Layzu
    Citation: BMC Complementary and Alternative Medicine 2015 15:128
  15. Plants are rich source of chemical compounds that are used to accomplish biological activity. Indigenously crude extracts of plants are widely used as herbal medicine for the treatment of infections by people ...

    Authors: Usman Ali Khan, Hazir Rahman, Muhammad Qasim, Anwar Hussain, Azizullah Azizllah, Waheed Murad, Zakir Khan, Muhammad Anees and Muhammad Adnan
    Citation: BMC Complementary and Alternative Medicine 2015 15:127
  16. Shenling Baizhu San (SBS) is a well-known and classical Chinese medicine formula. It has been used for treatment of gastrointestinal disorders for about nine hundred years. Recent reports showed that it was ef...

    Authors: Xiaochang Lin, Wenjuan Xu, Meng Shao, Qin Fan, Ge Wen, Changke Li, Linlin Jing and Xuegang Sun
    Citation: BMC Complementary and Alternative Medicine 2015 15:126
  17. Fructus mume (F. mume) has been used as a traditional medicine for many years in Asian countries. The present study was designed to determine the effect of a 70% ethanol extract of F. mume on white matter and hip...

    Authors: Ki Mo Lee, JiHye Bang, Bu Yeo Kim, In Sun Lee, Jung-Soo Han, Bang Yeon Hwang and Won Kyung Jeon
    Citation: BMC Complementary and Alternative Medicine 2015 15:125
  18. Caesalpinia sappan L. extracts exhibit great therapeutic potential, and have been shown to have analgesic and anti-inflammatory properties. This study aimed to understand the anti-rheumatoid activity of brazilin ...

    Authors: Eui-Gil Jung, Kook-Il Han, Seon Gu Hwang, Hyun-Jung Kwon, Bharat Bhusan Patnaik, Yong Hyun Kim and Man-Deuk Han
    Citation: BMC Complementary and Alternative Medicine 2015 15:124
  19. Mallotus philippinensis Muell. Arg (MP, Euphorbiaceae) are widely distributed perennial shrub or small tree in tropical and subtropical region in outer Himalayas regions. Since, Mallotus philippinensis have been ...

    Authors: Mayank Gangwar, Manish Kumar Gautam, Shivani Ghildiyal, Gopal Nath and Raj Kumar Goel
    Citation: BMC Complementary and Alternative Medicine 2015 15:123
  20. Yin-Chen-Hao-Tang (YCHT), a commonly used as a traditional chinese medicine for liver disease. Several studies indicated that YCHT may improving hepatic triglyceride metabolism and anti-apoptotic response as w...

    Authors: Qiaoling Yang, Fan Yang, Xiaowen Tang, Lili Ding, Ying Xu, Yinhua Xiong, Zhengtao Wang and Li Yang
    Citation: BMC Complementary and Alternative Medicine 2015 15:122
  21. Nidrakar Bati (NKB) is an herbal remedy consisted with seven medicinal herbs widely used to cure Somnifacient (sleeping aid) in South Asia as Ayurvedic medicinal system. In the present study, pharmacological and ...

    Authors: Afria Zaman, Md Shamsuddin Sultan Khan, Lucky Akter, Sharif Hossain Syeed, Jakia Akter, Abdullah Al Mamun, Md Ershad Alam, Md Ahsan Habib and Md Abdul Jalil
    Citation: BMC Complementary and Alternative Medicine 2015 15:121
  22. Body constitutional types described in the traditional Korean medicine system, Sasang constitutional medicine, are heritable, as has been revealed by twin and family studies. Thus, individuals with the same co...

    Authors: Seongwon Cha, Hyunjoo Yu, Ah Yeon Park, Soo A Oh and Jong Yeol Kim
    Citation: BMC Complementary and Alternative Medicine 2015 15:120
  23. Ginsenoside Rg1 (Rg1) is one of the most active ingredients in Panax ginseng and has been proven to have anti-oxidative and anti-aging properties. However, there have been few reports concerning the anti-aging ef...

    Authors: Wenxu Hu, Pengwei Jing, Lu Wang, Yanyan Zhang, Jiadao Yong and Yaping Wang
    Citation: BMC Complementary and Alternative Medicine 2015 15:119
  24. Identifying agents that inhibit amyloid beta peptide (Aβ) aggregation is the ultimate goal for slowing Alzheimer’s disease (AD) progression. This study investigated whether the glycoside asiaticoside inhibits Aβ1...

    Authors: Shahdat Hossain, Michio Hashimoto, Masanori Katakura, Abdullah Al Mamun and Osamu Shido
    Citation: BMC Complementary and Alternative Medicine 2015 15:118
  25. Oridonin, an ingredient used in traditional Chinese medicine, has been demonstrated to play an important role in antitumour effects, but the mechanism underlying its antitumour properties is still not clear.

    Authors: Zhifang Gui, Shuquan Li, Xing Liu, Bin Xu and Jian Xu
    Citation: BMC Complementary and Alternative Medicine 2015 15:117
  26. The incidence of resistance to the existing antibiotics by microorganisms demand increased effort in the development of new antibiotics for the treatment of microbial infections and diseases. Infections due to...

    Authors: David A Akinpelu, Kazeem A Alayande, Olayinka A Aiyegoro, Oluseun F Akinpelu and Anthony I Okoh
    Citation: BMC Complementary and Alternative Medicine 2015 15:116
  27. Ucche (Momordica charantia L. var. muricata (Willd.) Chakravarty) has been reported to possess many benefits and medicinal properties. However, the protective effect of ucche against carbon tetrachloride (CCl4) i...

    Authors: Abu Taher Sagor, Mohammed Riaz Hasan Chowdhury, Nabila Tabassum, Hemayet Hossain, Md Mahbubur Rahman and Md Ashraful Alam
    Citation: BMC Complementary and Alternative Medicine 2015 15:115
  28. Despite the popularity of naturopathic and herbal medicine in New Zealand there remains limited data on New Zealand-based naturopathic and herbal medicine practice.

    Authors: Phillip Cottingham, Jon Adams, Ram Vempati, Jill Dunn and David Sibbritt
    Citation: BMC Complementary and Alternative Medicine 2015 15:114
  29. So-Cheong-Ryong-Tang (SCRT), a traditional Korean medicine containing eight species of medicinal plant, has been used to treat patients with bronchial asthma and allergic rhinitis for hundreds of years; howeve...

    Authors: Cheol Park, Su Hyun Hong, Gi-Young Kim and Yung Hyun Choi
    Citation: BMC Complementary and Alternative Medicine 2015 15:113
  30. The decoction combination of Herba Epimedii and Fructus Ligustri Lucidi has been used to treat osteoporosis for almost 50 years by practitioners of traditional Chinese medicine. However, it is unclear what spe...

    Authors: Ren-Hui Liu, Xue Kang, Li-Ping Xu, Hong-Lei Nian, Xin-Wei Yang, Hao-Tian Shi and Xiu-Juan Wang
    Citation: BMC Complementary and Alternative Medicine 2015 15:112
  31. In the modern society, aging had been a major problem. People may rely on many medicines to delay it. However, lots of medicines were chemosynthetic, and they would do a bad side-effect on human body. Microbia...

    Authors: Liqin Wang, Cuiqin Wang, Xia Gao, Nuo Xu, Lin Lin, Huajie Zhao, Shouhua Jia and Le Jia
    Citation: BMC Complementary and Alternative Medicine 2015 15:111
  32. Lycopene is a robust antioxidant with significant antiulcer activity. Henceforth, the present study was ventured to elucidate the effect of lycopene on experimental esophagitis.

    Authors: Arvind Kumar Giri, Jitendra Kumar Rawat, Manjari Singh, Swetlana Gautam and Gaurav Kaithwas
    Citation: BMC Complementary and Alternative Medicine 2015 15:110
  33. Yindan Xinnaotong capsule has been used for treating cardio-cerebrovascular diseases for several decades in China. Exercise training can protect against the development of atherosclerosis. The aim of the prese...

    Authors: Jianlu Wang, Lan Wang, Hongjun Yang, Yun You, Haiyu Xu, Leilei Gong, Xiaojie Yin, Wandan Wang, Shuangrong Gao, Long Cheng, Rixin Liang and Fulong Liao
    Citation: BMC Complementary and Alternative Medicine 2015 15:109
  34. Hwangryunhaedok-tang (HHT) is a traditional herbal medicine that is used for the treatment of fever, inflammation, gastritis, and hypertension. In this study, we performed simultaneous determination of the fiv...

    Authors: Chang-Seob Seo, Ohn Soon Kim, Jung-Hoon Kim and Hyeun-Kyoo Shin
    Citation: BMC Complementary and Alternative Medicine 2015 15:108
  35. S. sylvestre Wright is an extremely rare plant, found only in the sub-Himalayan Terai region of West Bengal and neighboring Sikkim foot-hills. The plant has never been evaluated for any pharmaceutical properties....

    Authors: Priyankar Dey, Sandipan Ray, Mousumi Poddar Sarkar and Tapas Kumar Chaudhuri
    Citation: BMC Complementary and Alternative Medicine 2015 15:107
  36. The use and value of different complementary therapies requires investigation. In particular, qualitative research is required to understand the perceptions and experiences of patients who undergo healing ther...

    Authors: Andrew Soundy, Rhonda T Lee, Tom Kingstone, Sukhdev Singh, Pankaj R Shah and Lesley Roberts
    Citation: BMC Complementary and Alternative Medicine 2015 15:106

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2015 15:326

  37. In Japan, a traditional herbal medicine, Tokishigyakukagoshuyushokyoto (TJ-38), is often used for the treatment of peripheral coldness, which is a common complaint among Japanese women. However, the effects of th...

    Authors: Shinji Nishida, Eri Eguchi, Tetsuya Ohira, Akihiko Kitamura, Yukiko Hakariya Kato, Keisuke Hagihara and Hiroyasu Iso
    Citation: BMC Complementary and Alternative Medicine 2015 15:105
  38. Large dose application of traditional Chinese medicines has attracted more and more attentions in recent years. However, the scientific connotation of large dose application has not been clarified so far. The ...

    Authors: Yanling Zhao, Xiao Ma, Jiabo Wang, Ruiqing Wen, Lei Jia, Yun Zhu, Ruisheng Li, Ruilin Wang, Jianyu Li, Lifu Wang, Yonggang Li and Xiaohe Xiao
    Citation: BMC Complementary and Alternative Medicine 2015 15:104
  39. Primary insomnia is a common health issue in the modern world. We conducted a systematic review of the auricular therapy, aiming to evaluate whether there are advantages of auricular acupuncture with seed or p...

    Authors: Ying Lan, Xi Wu, Hui-Juan Tan, Nan Wu, Jing-Jing Xing, Fu-Sheng Wu, Lei-Xiao Zhang and Fan-Rong Liang
    Citation: BMC Complementary and Alternative Medicine 2015 15:103
  40. Traditional medicine (TM) has been established as a two-edged sword. On one edge numerous forms of TM have been proven safe and effective, while on the other edge various modes of TM have been shown to be futi...

    Authors: Yousef Mohammad, Ahmed Al-Ahmari, Fahad Al-Dashash, Fawaz Al-Hussain, Firas Al-Masnour, Abdullah Masoud and Hoda Jradi
    Citation: BMC Complementary and Alternative Medicine 2015 15:102
  41. In this study, we investigated the neuroprotective effect of the hairy root extract of Angelica gigas NAKAI (Angelica Gigantis Radix) on transient focal cerebral ischemia in rats through the regulation of angioge...

    Authors: Tae Woo Oh, Ki-Ho Park, Hyo Won Jung and Yong-Ki Park
    Citation: BMC Complementary and Alternative Medicine 2015 15:101
  42. Complementary and alternative medicine (CAM) has been practiced for centuries owing to the absence or limited availability of conventional medicine. CAM has persisted globally with over USD34 billion spent ann...

    Authors: Mandreker Bahall and Mark Edwards
    Citation: BMC Complementary and Alternative Medicine 2015 15:99
  43. In Taiwan, there is a good universal healthcare system to the patients; however, the majority of Taiwanese seek the complementary and alternative medicine when they are injured or ill. The traditional Chinese ...

    Authors: Chiu-Liang Chen, Shin-Lin Chiu, Chiao-Lee Chu and Shou-Jen Lan
    Citation: BMC Complementary and Alternative Medicine 2015 15:98
  44. Chinese medicine comprised of all natural herbs is widespread used in the treatment of diabetic nephropathy (DN). Podocyte contributes to the integrity of glomerular filtration barrier whose injury plays an im...

    Authors: Jingxin Zhou, Wen Sun, Hisae Yoshitomi, Linyi Li, Lingling Qin, Xiangyu Guo, Lili Wu, Yan Zhang, Xinli Wu, Tunhai Xu, Ming Gao and Tonghua Liu
    Citation: BMC Complementary and Alternative Medicine 2015 15:97
  45. Practitioners of complementary and alternative medicine (CAM) therapies are an important and growing presence in health care systems worldwide. A central question is whether evidence-based behavior change inte...

    Authors: Myra L Muramoto, Eva Matthews, Cheryl K Ritenbaugh and Mark A Nichter
    Citation: BMC Complementary and Alternative Medicine 2015 15:96
  46. Many smokers are unable to access effective behavioral smoking cessation therapies due to location, financial limitations, schedule, transportation issues or other reasons. We report results from a prospective...

    Authors: James M Davis, Alison R Manley, Simon B Goldberg, Kristin A Stankevitz and Stevens S Smith
    Citation: BMC Complementary and Alternative Medicine 2015 15:95
  47. Grape seeds extract (GSE) is a famous health food supplement for its antioxidant property. Different concentrations of GSE may have different impacts on cellular oxidative/reduction homeostasis. Antiproliferat...

    Authors: Ching-Yu Yen, Ming-Feng Hou, Zhi-Wen Yang, Jen-Yang Tang, Kun-Tzu Li, Hurng-Wern Huang, Yu-Hsuan Huang, Sheng-Yang Lee, Tzu-Fun Fu, Che-Yu Hsieh, Bing-Hung Chen and Hsueh-Wei Chang
    Citation: BMC Complementary and Alternative Medicine 2015 15:94
  48. One of the most common symptoms observed in patients with dementia is agitation, and several non-pharmacological treatments have been used to control this symptom. However, because of limitations in research d...

    Authors: Man-Hua Yang, Li-Chan Lin, Shiao-Chi Wu, Jen-Hwey Chiu, Pei-Ning Wang and Jaung-Geng Lin
    Citation: BMC Complementary and Alternative Medicine 2015 15:93