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  1. Clinacanthus nutans is used traditionally in many parts of Asia to improve well-being, but there are limited studies on its efficacy. We explored the potential use of C. nutans for pre...

    Authors: Nadarajan Sarega, Mustapha Umar Imam, Norhaizan Md Esa, Norhasnida Zawawi and Maznah Ismail
    Citation: BMC Complementary and Alternative Medicine 2016 16:88
  2. The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be fou...

    Authors: Nadiah Abu, M. Nadeem Akhtar, Swee Keong Yeap, Kian Lam Lim, Wan Yong Ho, Mohd Puad Abdullah, Chai Ling Ho, Abdul Rahman Omar, Jamil Ismail and Noorjahan Banu Alitheen
    Citation: BMC Complementary and Alternative Medicine 2016 16:86
  3. Acupuncture is applied for treating numerous conditions in children, but few studies have examined the safe needling depth of acupoints in the pediatric population. In this study, we investigated the depths to...

    Authors: Yi-Chun Ma, Ching-Tien Peng, Yu-Chuen Huang, Hung-Yi Lin and Jaung-Geng Lin
    Citation: BMC Complementary and Alternative Medicine 2016 16:85
  4. Type 2 diabetes mellitus is a major health threat worldwide. Cosmos caudatus is one of the medicinal plants used to treat type 2 diabetes. Therefore, this study aims to determine the effectiveness and safety of C...

    Authors: Shi-Hui Cheng, Amin Ismail, Joseph Anthony, Ooi Chuan Ng, Azizah Abdul Hamid and Barakatun-Nisak Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2016 16:84
  5. The Amazon is the largest rainforest in the world and is home to a rich biodiversity of medicinal plants. Several of these plants are used by the local population for the treatment of diseases, many of those w...

    Authors: Fabiano S. de Vargas, Patricia D. O. Almeida, Ana Paula A. de Boleti, Maria M. Pereira, Tatiane P. de Souza, Marne C. de Vasconcellos, Cecilia Veronica Nunez, Adrian M. Pohlit and Emerson S. Lima
    Citation: BMC Complementary and Alternative Medicine 2016 16:83

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2016 16:119

  6. Recurrent respiratory tract infections (RRTIs) have a negative impact on both children’s health and family wellbeing. Deficiency of ZhengQi used to be an instinct factor driving RRTI in Traditional Chinese Med...

    Authors: Fei Dong, He Yu, Jiaju Ma, Liqun Wu, Tiegang Liu, Guokai Lv, Jianhua Zhen, Xiaofei Li, George Lewith and Xiaohong Gu
    Citation: BMC Complementary and Alternative Medicine 2016 16:82
  7. The EUDAIMON study focuses on fibromyalgia syndrome (FMS), a prevalent chronic condition characterized by pain, fatigue, cognitive problems and distress. According to recent reviews and meta-analyses, Mindfuln...

    Authors: Albert Feliu-Soler, Xavier Borràs, María T. Peñarrubia-María, Antoni Rozadilla-Sacanell, Francesco D’Amico, Rona Moss-Morris, Matthew A. Howard, Nicolás Fayed, Carles Soriano-Mas, Marta Puebla-Guedea, Antoni Serrano-Blanco, Adrián Pérez-Aranda, Raffaele Tuccillo and Juan V. Luciano
    Citation: BMC Complementary and Alternative Medicine 2016 16:81
  8. Anoectochilus formosanus has been used as a Chinese folk medicine and is known as the “King of medicine” in Chinese society due to its versatile pharmacological effects such as anti-hy...

    Authors: Hung-Bo Hsiao, Chang-Chi Hsieh, Jin-Bin Wu, Ho Lin and Wen-Chuan Lin
    Citation: BMC Complementary and Alternative Medicine 2016 16:80
  9. Muntingia calabura L. (family Muntingiaceae), commonly known as Jamaican cherry or kerukup siam in Malaysia, is used traditionally to treat various ailments. The aim of this study is t...

    Authors: Zainul Amiruddin Zakaria, Tavamani Balan, Ahmad Khusairi Azemi, Maizatul Hasyima Omar, Norhafizah Mohtarrudin, Zuraini Ahmad, Muhammad Nazrul Hakim Abdullah, Mohd. Nasir Mohd. Desa, Lay Kek Teh and Mohd. Zaki Salleh
    Citation: BMC Complementary and Alternative Medicine 2016 16:78
  10. Passiflora incarnata is widely used as an anxiolytic and sedative due to its putative GABAergic properties. Passiflora incarnata L. methanolic extract (PI-ME) was evaluated in an anima...

    Authors: Urooj Aman, Fazal Subhan, Muhammad Shahid, Shehla Akbar, Nisar Ahmad, Gowhar Ali, Khwaja Fawad and Robert D. E. Sewell
    Citation: BMC Complementary and Alternative Medicine 2016 16:77
  11. This study aimed to evaluate the effects of Gelam honey on corneal keratocytes proliferative capacity and phenotypic characterization via MTT assay, gene expression and immunocytochemistry.

    Authors: Alia Md Yusof, Norzana Abd Ghafar, Taty Anna Kamarudin, Chua Kien Hui and Yasmin Anum Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2016 16:76
  12. Research on continued CAM use has been largely atheoretical and has not considered the broader range of psychological and behavioral factors that may be involved. The purpose of this study was to test a new co...

    Authors: Fuschia M. Sirois, Anita Salamonsen and Agnete E. Kristoffersen
    Citation: BMC Complementary and Alternative Medicine 2016 16:75
  13. Production of reactive oxygen species is a common cause in alcohol induced liver diseases. Decoction prepared from the whole plant of Eriocaulon quinquingulare is prescribed to treat liver disorders. The aim of t...

    Authors: Chamira Dilanka Fernando and Preethi Soysa
    Citation: BMC Complementary and Alternative Medicine 2016 16:74
  14. Kansui Radix (Gansui in Chinese), the dried tuber of Euphorbia kansui, is a Chinese medicinal herb commonly used for the treatment of oedema and ascites with dyspnea. Because of its toxic nature, the herb is usua...

    Authors: Xin Shu, Xi-Wen Jiang, Brian Chi-Yan Cheng, Shuang-Cheng Ma, Guang-Ying Chen and Zhi-Ling Yu
    Citation: BMC Complementary and Alternative Medicine 2016 16:73
  15. This study investigates the protective effects of turmeric (Curcuma longa, CL) on acetic acid-induced colitis in rats.

    Authors: Salim M. A. Bastaki, Mohammed Majed Al Ahmed, Ahmed Al Zaabi, Naheed Amir and Ernest Adeghate
    Citation: BMC Complementary and Alternative Medicine 2016 16:72
  16. Diabetes mellitus is a metabolic disorder which is rising globally in rich and developing countries. In the African region this rate is the highest, with 20 million diagnosed diabetics. Despite a noticeable pr...

    Authors: Huguette Agnaniet, Elvis Jolinom Mbot, Ousmane Keita, Jean-Alain Fehrentz, Anita Ankli, Audrey Gallud, Marcel Garcia, Magali Gary-Bobo, Jacques Lebibi, Thierry Cresteil and Chantal Menut
    Citation: BMC Complementary and Alternative Medicine 2016 16:71
  17. Fibrosis is a major contributor to systemic sclerosis (SSc)-related morbidity, and rapid, progressive skin involvement predicts later mortality. Western medicine therapies for SSc cannot produce satisfactory e...

    Authors: Li Han, Hua Bian, Jingfeng Ouyang, Yuefeng Bi, Lei Yang and Songshan Ye
    Citation: BMC Complementary and Alternative Medicine 2016 16:69
  18. To appraise critically whether published trials of ShenXiong glucose injection for patients with acute ischemic stroke (AIS) are of sufficient quality, and in addition to rate the quality of evidence by using ...

    Authors: Xue-ting Liu, Peng-wei Ren, Le Peng, De-ying Kang, Tian-le Zhang, Shu Wen, Qi Hong and Wen-jie Yang
    Citation: BMC Complementary and Alternative Medicine 2016 16:68
  19. HemoHIM, which is an herbal preparation of three edible herbs (Angelicam gigas Nakai, Cnidium offinale Makino, and Peaonia japonica Miyabe), is known to have various biological and immunological activities, but t...

    Authors: Sung-Ju Lee, Jong-Jin Kim, Kyung-Yun Kang, Yun-Ho Hwang, Gil-Yeon Jeong, Sung-kee Jo, Uhee Jung, Hae-Ran Park and Sung-Tae Yee
    Citation: BMC Complementary and Alternative Medicine 2016 16:67
  20. Ginseng (Panax ginseng C.A. Meyer) has been used as a traditional herb in the treatment of many medical disorders. Ginsenosides, which are triterpene derivatives that contain sugar moieties, are the main pharmaco...

    Authors: Jiyoung Kim, Jaesung Shim, Siyoung Lee, Woo-Hyun Cho, Eunyoung Hong, Jin Hee Lee, Jung-Soo Han, Hyong Joo Lee and Ki Won Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:66
  21. Propolis (or bee glue), collected from botanical sources by honey bee, has been used as a popular natural remedies in folk medicine throughout the world. This study was conducted to assess growth inhibitory ef...

    Authors: Xue Wang, Karuppasamy Sankarapandian, Yizhe Cheng, Soon Ok Woo, Hyung Wook Kwon, Haribalan Perumalsamy and Young-Joon Ahn
    Citation: BMC Complementary and Alternative Medicine 2016 16:65
  22. Of patients undergoing surgery, 22 to 57 % have been reported to be using naturopathic medicines. Several of these medicines have been reported to increase bleeding or enhance the effect of other drugs that in...

    Authors: August Bagge, Ulf Schött and Thomas Kander
    Citation: BMC Complementary and Alternative Medicine 2016 16:64
  23. Water extract from the root of Allium hookeri (AH) shows anti-inflammatory, antioxidant, and free radical scavenging effects. In this study, the ameliorating effects of AH on oxidative stress-induced inflammatory...

    Authors: Seong-Soo Roh, O Jun Kwon, Jae Heon Yang, You Suk Kim, Sung Hyun Lee, Jong-Sik Jin, Yong-Deok Jeon, Takako Yokozawa and Hyun Ju Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:63
  24. Ayurveda has its historical roots in India, but has also been internationalised, partly via migration and partly through an increased interest in alternative medicine in the West, where studies point toward in...

    Authors: Maria Niemi and Göran Ståhle
    Citation: BMC Complementary and Alternative Medicine 2016 16:62
  25. Sheng-Mai Yin (SMY), a modern Chinese formula based on Traditional Chinese Medicine theory, has been used to treat cardiovascular diseases in Eastern Asia. Our study focuses on the cardioprotection of SMY agai...

    Authors: Shaojun Ma, Xiaojiang Li, Liang Dong, Jinli Zhu, He Zhang and Yingjie Jia
    Citation: BMC Complementary and Alternative Medicine 2016 16:61
  26. Anxiety disorders are the most prevalent mental health condition in Australia. In addition, there are many people who experience problematic anxiety symptoms who do not receive an anxiety disorder diagnosis bu...

    Authors: Erica McIntyre, Anthony J. Saliba, Karl K. Wiener and Jerome Sarris
    Citation: BMC Complementary and Alternative Medicine 2016 16:60
  27. The hypertriglyceridemic waist (HW) phenotype has been shown to be strongly associated with metabolic abnormalities; however, to date, no study has reported the prediction of metabolic abnormalities using the ...

    Authors: Bum Ju Lee, Jiho Nam and Jong Yeol Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:59
  28. Paris polyphylla is an oriental folk medicine that has anticancer activities both in vivo and in vitro. Polyphyllin VII (PP7), a pennogenyl saponin from P. polyphylla has been found to...

    Authors: Chao Zhang, Xuejing Jia, Jiaolin Bao, Shenghui Chen, Kai Wang, Yulin Zhang, Peng Li, Jian-Bo Wan, Huanxing Su, Yitao Wang, Zhinan Mei and Chengwei He
    Citation: BMC Complementary and Alternative Medicine 2016 16:58
  29. Far-infrared ray (FIR) has been widely used in promoting health and has been shown to exert beneficial effects in vascular function. The non-thermal effect of FIR has been found to play a significant role in t...

    Authors: Chien-Tsong Lin, Ming-Ju Lin, Yung-Pin Chen, Ko-Chao Lee, Kuo-Chin Huang, Shun-Fu Chang and Cheng-Nan Chen
    Citation: BMC Complementary and Alternative Medicine 2016 16:57
  30. Xue-Fu-Zhu-Yu decoction (XFZYD), Tian-Ma-Gou-Teng-Yin (TMGTY) and Wen-Dan decoction (WDD) are Chinese herbal formulas used to treat hypertension and cardiovascular diseases in traditional Chinese medicine (TCM...

    Authors: Guohua Zhang, Guang Yang, Yan Deng, Xiangling Zhao, Yingbao Yang, Jinjun Rao, Wenya Wang, Xin Liu, Jian He and Lin Lv
    Citation: BMC Complementary and Alternative Medicine 2016 16:56
  31. Emu oil is a product of animal origin used for the treatment of inflammation, burns etc. as a part of aboriginal medicine in Australia. Crohn’s disease is a common inflammatory manifestation in humans and othe...

    Authors: Bhaskar Vemu, S. Selvasubramanian and V. Pandiyan
    Citation: BMC Complementary and Alternative Medicine 2016 16:55
  32. Fructus mume (F. mume) has been used as a traditional treatment for ulcer, cough, and digestive problems for many years in Asian countries. Previous studies have demonstrated that F. m...

    Authors: Jung-Cheol Park, Jinhua Ma, Won Kyung Jeon and Jung-Soo Han
    Citation: BMC Complementary and Alternative Medicine 2016 16:54

    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2016 16:426

  33. Integrative medicine (IM) provides patient-centered care and addresses the full range of physical, emotional, mental, social, spiritual, and environmental influences that affect a person’s health. IM is a “who...

    Authors: Jeffery A. Dusek, Donald I. Abrams, Rhonda Roberts, Kristen H. Griffin, Desiree Trebesch, Rowena J. Dolor, Ruth Q. Wolever, M. Diane McKee and Benjamin Kligler
    Citation: BMC Complementary and Alternative Medicine 2016 16:53
  34. Symptomatic cervical intervertebral disc herniation (IDH) presenting as neck pain accompanied by arm pain is a common affliction whose prevalence continues to rise, and is a frequent reason for integrative inp...

    Authors: Sang Hyun Baek, Jae Woo Oh, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-riong Kim, Yong-jun Ahn, Areum Choi, Ki Byung Park, Byung-Cheul Shin, Myeong Soo Lee and In-Hyuk Ha
    Citation: BMC Complementary and Alternative Medicine 2016 16:52
  35. In this study, we investigated the anti-obesity and anti-hyperlipidemic mechanisms of lambertianic acid (LA) isolated from Pinus koraiensis leaves and the ethanol extract of Pinus koraiensis leaves (EPK), both in...

    Authors: Myoung-Sun Lee, Sun-Mi Cho, Min-ho Lee, Eun-Ok Lee, Sung-Hoon Kim and Hyo-Jeong Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:51
  36. Despite high quality stroke care, decreased sensorimotor function, anxiety and pain often remain one year after stroke which can lead to impaired health and dependence, as well as higher healthcare costs. Touc...

    Authors: Kristina Lämås, Charlotte Häger, Lenita Lindgren, Per Wester and Christine Brulin
    Citation: BMC Complementary and Alternative Medicine 2016 16:50
  37. Gualou Xiebai Decoction (GXD) is a well-known traditional Chinese recipe. It has been used to treat cardiovascular disorders for nearly two thousand years. But there is a lack of reports on cardiac fibrosis an...

    Authors: Yong-fang Ding, Yun-ru Peng, Hong Shen, Luan Shu and Ying-jie Wei
    Citation: BMC Complementary and Alternative Medicine 2016 16:49
  38. Traditional medicine (TM) still plays an important role in a number of health care systems around the world, especially across Asian and African countries. In Vietnam, however, little is known about preference...

    Authors: Bach Xuan Tran, Ngan Kim Nguyen, Lan Phuong Nguyen, Cuong Tat Nguyen, Vuong Minh Nong and Long Hoang Nguyen
    Citation: BMC Complementary and Alternative Medicine 2016 16:48
  39. Consumption of foods rich in carbohydrates and fats, result in an increase in obesity and consequently type 2 diabetes. The present study was carried out to evaluate the effects of oxidised palm oil and sucros...

    Authors: Florence Tsofack Ngueguim, Eloi Christian Esse, Paul Désiré Djomeni Dzeufiet, Raceline Kamkumo Gounoue, Danielle Claude Bilanda, Pierre Kamtchouing and Théophile Dimo
    Citation: BMC Complementary and Alternative Medicine 2016 16:47
  40. Chronic cough, defined it lasts more than 8 weeks. The symptom is common, but highly troublesome, and it reduces quality of life. Despite much effort to develop a protocol for diagnosis and treatment of chroni...

    Authors: Kwan-Il Kim, Seungwon Shin, Kyuseok Kim and Junhee Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:46
  41. The purpose of this study is to evaluate the efficacy and safety of myofascial-meridian release acupuncture (MMRA) in the treatment of chronic neck pain compared with sham acupuncture.

    Authors: Seunghoon Lee, Dongwoo Nam, Jungtae Leem, Gajin Han, Seungmin Lee and Junhee Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:45
  42. Probiotics have rarely been studied in young healthy infants from low-income countries. This phase I study investigated the safety and acceptability of two probiotics in Bangladesh.

    Authors: Yana Emmy Hoy-Schulz, Kaniz Jannat, Thomas Roberts, Saira Husain Zaidi, Leanne Unicomb, Stephen Luby and Julie Parsonnet
    Citation: BMC Complementary and Alternative Medicine 2016 16:44
  43. Although various placebo acupuncture devices have been developed and used in acupuncture research, there is controversy concerning whether these devices really serve as appropriate placebos for control groups.

    Authors: Jungtae Leem, Jimin Park, Gajin Han, Seulgi Eun, Meena M. Makary, Kyungmo Park, Junhee Lee and Sanghoon Lee
    Citation: BMC Complementary and Alternative Medicine 2016 16:43
  44. Cervical cancer is the second most common cancer in females. Recent reports have revealed the critical role of cervical cancer stem cells (CSCs) in tumorigenicity and metastasis. Previously we demonstrated tha...

    Authors: Taeho Kwon, Yesol Bak, Sun-Young Ham, Dae-Yeul Yu and Do-Young Yoon
    Citation: BMC Complementary and Alternative Medicine 2016 16:42
  45. The present therapeutic agents for the treatment of pain, inflammation and pyrexia are not very effective and accompanied by various side effects. Therefore, new effective agents are the most wanted. The prese...

    Authors: Naila Raziq, Muhammad Saeed, Muhammad Shahid, Naveed Muhammad, Haroon Khan and Farah Gul
    Citation: BMC Complementary and Alternative Medicine 2016 16:41
  46. Buruli ulcer, caused by Mycobacterium ulcerans, is a localized skin lesion that can progress to extensive ulceration and necrosis if left untreated. Unpublished studies of hydrated clays for therapeutic, topical ...

    Authors: Sarojini Adusumilli and Shelley E. Haydel
    Citation: BMC Complementary and Alternative Medicine 2016 16:40
  47. Kudzu (Pueraria thunbergiana) root has long been used in Traditional Chinese Medicine. However, the vine of the kudzu plant has been considered waste material. This study aimed to investigate the hepatoprotective...

    Authors: Bo Yoon Chang, Dong-Sung Lee, Jun-Kyoung Lee, Youn-Chul Kim, Hyoung-Kwon Cho and Sung Yeon Kim
    Citation: BMC Complementary and Alternative Medicine 2016 16:39