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  1. Osteochondral defects caused by an acute traumatic injury or articular degeneration remains difficult to be manipulated. Repair of articular defects is still a great challenge for both tissue engineers and ort...

    Authors: Juntao Zhang, Dong Ming, Qiang Ji, Aifeng Liu, Chao Zhang, Jianjie Jiao and Man Shang
    Citation: BMC Complementary Medicine and Therapies 2020 20:193
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:336

  2. The flowers and dried fruit spikes of Prunella vulgaris L. (P. vulgaris L.) have been widely used in traditional Chinese medicine and food. P. vulgaris L. is regarded as a good option for treating uterine myoma (...

    Authors: Yan Lin, Chao Yang, Jie Tang, Chun Li, Zhi-min Zhang, Bo-hou Xia, Ya-mei Li, Qing-zhi He, Li-mei Lin and Duan-fang Liao
    Citation: BMC Complementary Medicine and Therapies 2020 20:189
    Content type: Research article Published on:

  3. Cancer is a horrific disease relentlessly affecting human population round the globe. Genus Datura encompasses numerous species with reported medicinal uses. However, its potential as a source of natural anticanc...

    Authors: Bakht Nasir, Muhammad Waleed Baig, Muhammad Majid, Syeda Masooma Ali, Muhammad Zafar Irshad Khan, Syeda Tayyaba Batool Kazmi and Ihsan-ul Haq
    Citation: BMC Complementary Medicine and Therapies 2020 20:188
    Content type: Research article Published on:

  4. To evaluate the in vitro antibacterial effect of flavonoids-rich Ziziphus jujuba Mill. extract (FZM) against the formation of bacterial biofilms (BBFs) in Staphylococcus aureus.

    Authors: Weiwei Miao, Lei Sheng, Tao Yang, Guizhen Wu, Minfang Zhang, Juan Sun and Aikemu Ainiwaer
    Citation: BMC Complementary Medicine and Therapies 2020 20:187
    Content type: Research article Published on:

  6. Isaria tenuipes is one of the potent species in the members of the genus Isaria, which is well reported to possess multiple bioactive substances of therapeutic importance. Therefore, an in vitro experimental stud...

    Authors: Dhani Raj Chhetri, Abhijit Chhetri, Nerina Shahi, Snigdha Tiwari, Shibendra Kumar Lal Karna, Dorjay Lama and Yuba Raj Pokharel
    Citation: BMC Complementary Medicine and Therapies 2020 20:185
    Content type: Research article Published on:

  7. Mahasudarshan Churna (MC) is a polyherbal Ayurvedic medicine that is employed in fever (especially chronic type), cold and malaria, improvement of digestion and appetite, removes toxins from the blood, boosts ...

    Authors: Prabhjot Kaur, R. C. Gupta, Abhijit Dey, Tabarak Malik and Devendra Kumar Pandey
    Citation: BMC Complementary Medicine and Therapies 2020 20:184
    Content type: Research article Published on:

  8. Many studies have shown that sociodemographic variables significantly predict the use of complementary and alternative medicine (CAM), although these predictions were not particularly strong. A multitude of pr...

    Authors: Henrik Abheiden, Michael Teut and Anne Berghöfer
    Citation: BMC Complementary Medicine and Therapies 2020 20:183
    Content type: Research article Published on:

  9. African Potato (hypoxis hemerocallidea), is used for enhancing immune system in Southern Africa. It is among the plants of intense commercial and scientific interest; hence, the aim of this study was to describe ...

    Authors: Celia M. J. Matyanga, Gene D. Morse, Mazuru Gundidza and Charles F. B. Nhachi
    Citation: BMC Complementary Medicine and Therapies 2020 20:182
    Content type: Research article Published on:

  10. Peripheral nerve injury is a debilitating condition that may lead to partial or complete motor, sensory and autonomic function loss and lacks effective therapy until date. Therefore, it is quite imperative to ...

    Authors: Aroona Razzaq, Ghulam Hussain, Azhar Rasul, Jiaqi Xu, Qiqi Zhang, Shoaib Ahmad Malik, Haseeb Anwar, Nimra Aziz, Nady Braidy, Jose-Luis Gonzalez de Aguilar, Wei Wei, Jiang Li and Xiaomeng Li
    Citation: BMC Complementary Medicine and Therapies 2020 20:181
    Content type: Research article Published on:

  11. The Chinese herbal compound Heshouwuyin has been shown to downregulate the apoptotic rate of testicular tissue cells in Wistar naturally aging rats, and this effect might be related to the mitochondrial pathwa...

    Authors: Hongjie Wang, Juan Zhu, Liping Jiang, Boying Shan, Peihan Xiao, Jiayi Ai, Na Li, Feng Qi and Siyun Niu
    Citation: BMC Complementary Medicine and Therapies 2020 20:180
    Content type: Research article Published on:

  12. Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon and rectum, which is positively correlated with the occurrence of IBD-related colorectal cancer (IBD-CRC). Conventional therapies based o...

    Authors: Shaohua Huangfu, Renjie Dou, Sixia Zhong, Mengjie Guo, Chunyan Gu, Artur Jurczyszyn, Ye Yang and Bin Jiang
    Citation: BMC Complementary Medicine and Therapies 2020 20:179
    Content type: Research article Published on:

  13. Pancreatic cancer is aggressive with no symptoms until the advanced stage reached. The increased resistance of pancreatic cancer to chemotherapy demonstrates a dilemma in the clinical field. Hence, it is a mat...

    Authors: Yangyang Guo, Hengyue Zhu, Min Weng, Cheng Wang and Linxiao Sun
    Citation: BMC Complementary Medicine and Therapies 2020 20:178
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2021 21:131

  14. 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) is an active compound derived from Polygonum multiflorum Thunb., a Chinese Taoist herbal medicine, which exerts lipid lowering, anti-cancer, anti-aging, anti-...

    Authors: Xuanbin Wang, Jing Zeng, Xiao Wang, Ju Li, Jin Chen, Ning Wang, Miao Zhang, Yibin Feng and Huailan Guo
    Citation: BMC Complementary Medicine and Therapies 2020 20:177
    Content type: Research article Published on:

  15. Glucocorticoids (GCs) are anti-inflammatory drugs widely used to treat acute and chronic inflammatory diseases. However, despite their excellent efficacy, the long-term use of GCs is relatively limited owing t...

    Authors: Ji Hyun Seo, Mu Hyun Jin and Yun Hee Chang
    Citation: BMC Complementary Medicine and Therapies 2020 20:176
    Content type: Research article Published on:

  17. Javanica oil emulsion injection (JOEI) is an effective therapeutic option for patients with non-small cell lung cancer (NSCLC), but its mechanisms have not been fully elucidated.

    Authors: Mengwei Ni, Xinkui Liu, Ziqi Meng, Shuyu Liu, Shanshan Jia, Yingying Liu, Wei Zhou, Jiarui Wu, Jingyuan Zhang, Siyu Guo, Jialin Li, Haojia Wang and Xiaomeng Zhang
    Citation: BMC Complementary Medicine and Therapies 2020 20:174
    Content type: Research article Published on:

  18. About 1 in every 150 pregnancies end in stillbirth. Consequences include symptoms of post traumatic stress disorder (PTSD), depression, and anxiety. Yoga has been used to treat PTSD in other populations and ma...

    Authors: Jennifer Huberty, Mariah Sullivan, Jeni Green, Jonathan Kurka, Jenn Leiferman, Katherine Gold and Joanne Cacciatore
    Citation: BMC Complementary Medicine and Therapies 2020 20:173
    Content type: Research article Published on:

  19. The root of Morinda officinalis How. (MO, the family of Rubiaceae) has long been used to treat inflammatory diseases in China and other eastern Asian countries, and iridoid glycosides extracted from MO (MOIG) are...

    Authors: Qi Zhang, Jian-hua Zhang, Yu-qiong He, Quan-long Zhang, Bo Zhu, Yi Shen, Meng-qin Liu, Lu-lin Zhu, Hai-liang Xin, Lu-ping Qin and Qiao-yan Zhang
    Citation: BMC Complementary Medicine and Therapies 2020 20:172
    Content type: Research article Published on:

  20. Occipital neuralgia is one of the main causes of occipital pain. This systematic review aims to assess the level of evidence in randomized controlled trials (RCTs) on the effects of acupuncture on occipital ne...

    Authors: Jung-Min Yun, Sook-Hyun Lee, Jae-Heung Cho, Koh-Woon Kim and In-Hyuk Ha
    Citation: BMC Complementary Medicine and Therapies 2020 20:171
    Content type: Research article Published on:

  21. Several reports have shown that traditional Chinese medicine could be an alternative therapeutic approach for COPD patients, but the mechanism remains unknown. The present study aimed to examine the effects of...

    Authors: Liuliu Yang, Minyong Wen, Xiaohong Liu, Kai Wang and Yong Wang
    Citation: BMC Complementary Medicine and Therapies 2020 20:170
    Content type: Research article Published on:

  22. There is some evidence that patients with liver diseases commonly use complementary and alternative therapies to address general and liver-disease specific health concerns. The purpose of this study was to ass...

    Authors: Sara Nsibirwa, Godwin Anguzu, Sam Kamukama, Ponsiano Ocama and Joan Nankya-Mutyoba
    Citation: BMC Complementary Medicine and Therapies 2020 20:169
    Content type: Research article Published on:

  23. Pneumonia is a common respiratory disorder, which brings an enormous financial burden to the medical system. However, the current treatment options for pneumonia are limited because of drug resistance and side...

    Authors: Jingnan Xu, Chen Bai, Ling Huang, Tiegang Liu, Yuxiang Wan, Zian Zheng, Xueyan Ma, Fei Gao, He Yu and Xiaohong Gu
    Citation: BMC Complementary Medicine and Therapies 2020 20:168
    Content type: Research article Published on:

  24. Previous studies indicate that soyasaponins may reduce inflammation via modulating toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signaling. However, its underlying mechanisms are still ...

    Authors: Junbin Chen, Hidayat Ullah, Zhongdaixi Zheng, Xiangfu Gu, Chuhong Su, Lingyu Xiao, Xinglong Wu, Fei Xiong, Qing Li and Longying Zha
    Citation: BMC Complementary Medicine and Therapies 2020 20:167
    Content type: Research article Published on:

  25. The purpose of this study was to identify the clinicopathologic characteristics and prognosis of upper tract urothelial carcinoma (UTUC) patients complicated with aristolochic acid nephropathy(AAN) after radic...

    Authors: Hongli Shan, Wen Tian, Yazhao Hong, Bo Xu, Chunxi Wang, Bing Yu and Xiaoqing Wang
    Citation: BMC Complementary Medicine and Therapies 2020 20:166
    Content type: Research article Published on:

  26. Traditional medicine use is common amongst peoples in developing nations. Timor-Leste is no exception. However little is known about the prevalence, pattern, satisfaction with, cost or type of traditional medi...

    Authors: Robert Grace, Jacinto Vaz and Julianti Da Costa
    Citation: BMC Complementary Medicine and Therapies 2020 20:165
    Content type: Research article Published on:

  27. Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost t...

    Authors: Anna Misya’il Abdul Rashid, Fauzah Abd Ghani, Liyana Najwa Inche Mat and Christopher Thiam Seong Lim
    Citation: BMC Complementary Medicine and Therapies 2020 20:163
    Content type: Case report Published on:

  28. Angelica root is the dry root of the Umbelliferae plant Angelica sinensis (oliv) Diels. Angelica organic acid (OA) is the main active ingredient in Angelica sinensis, and it exerts potential anti-atherosclerotic ...

    Authors: Xuefeng Li, Jing Zhou, Yinghuan Dou, Yanbin Shi, Ying Wang, Jianli Hong, Junnan Zhao, Jiaying Zhang, Yang Yuan, Mengru Zhou and Xiangxiang Wei
    Citation: BMC Complementary Medicine and Therapies 2020 20:164
    Content type: Research article Published on:

  29. The prevalence of nonalcoholic steatohepatitis (NASH) in menopausal women is increasing, but current treatments have not been proven effective. The objective of this study was to investigate the treatment effe...

    Authors: Namthip Witayavanitkul, Duangporn Werawatganon, Maneerat Chayanupatkul, Naruemon Klaikeaw, Sompol Sanguanrungsirikul and Prasong Siriviriyakul
    Citation: BMC Complementary Medicine and Therapies 2020 20:162
    Content type: Research article Published on:

  30. Previous studies have acknowledged Tai Chi and Qigong exercise could be potential effective treatments for reducing depression and anxiety in both healthy and clinical populations. However, there is a scarcity...

    Authors: Fang Liu, Jiabao Cui, Xuan Liu, Kevin W. Chen, Xiaorong Chen and Ru Li
    Citation: BMC Complementary Medicine and Therapies 2020 20:161
    Content type: Research article Published on:

  31. To investigate the protective effects of Tualang honey against the toxicity effects induced by cadmium (Cd) on the ovary.

    Authors: Siti Suraya Ruslee, Siti Sarah Mohamad Zaid, Ikmal Hisyam Bakrin, Yong Meng Goh and Noordin Mohamed Mustapha
    Citation: BMC Complementary Medicine and Therapies 2020 20:160
    Content type: Research article Published on:

  32. Shen-ling-bai-zhu-san (SLBZS) regulates inflammation and gut microbiota which are associated with Streptococcus pneumoniae (Spn)-induced pneumonia. So, we studied the therapeutic effect of SLBZS and evaluated whe...

    Authors: Jinli Feng, Weibo Dai, Cheng Zhang, Houjun Chen, Ziliang Chen, Yongfeng Chen, Qianyi Pan and Yongmao Zhou
    Citation: BMC Complementary Medicine and Therapies 2020 20:159
    Content type: Research article Published on:

  33. Whole body vibration (WBV) is currently increasing in popularity as a treatment modality for musculoskeletal disorders and improving health-related quality of life. Recent research has shown that WBV can reduc...

    Authors: Weiming Wang, Shuting Wang, Wujian Lin, Xian Li, Lars L. Andersen and Yuling Wang
    Citation: BMC Complementary Medicine and Therapies 2020 20:158
    Content type: Research article Published on:

  34. Shanzhuyu (the dried mature sarcocarp of Cornus officinalis Sieb. et Zucc., DMSCO) is a Chinese herb that can be used for the treatment of Alzheimer’s disease (AD), but its mechanism remains unknown. The present ...

    Authors: Yan-Jie Qu, Rong-Rong Zhen, Li-Min Zhang, Chao Gu, Lei Chen, Xiao Peng, Bing Hu and Hong-Mei An
    Citation: BMC Complementary Medicine and Therapies 2020 20:157
    Content type: Research article Published on:

  35. The present study examines the antimicrobial activity of nasturtium herb (Tropaeoli maji herba) and horseradish root (Armoraciae rusticanae radix) against clinically important oral bacterial pathogens involved in...

    Authors: Vanessa Eichel, Anne Schüller, Klaus Biehler, Ali Al-Ahmad and Uwe Frank
    Citation: BMC Complementary Medicine and Therapies 2020 20:156
    Content type: Research article Published on:

  36. Traditionally part of the human diet, plants with edible fleshy fruits (PEFF) contain bioactive components that may exert physiological effects beyond nutrition, promoting human health and well-being. Focusing...

    Authors: Melina Fernanda Chamorro and Ana Ladio
    Citation: BMC Complementary Medicine and Therapies 2020 20:155
    Content type: Research article Published on:

  37. Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to exert biological effects via toll-like receptor 4 (TLR4). Recently, TLR4 was described as involved in natural p...

    Authors: Adila El-Obeid, Hala Alajmi, Mashael Harbi, Wesam Bin Yahya, Hamad Al-Eidi, Monira Alaujan, Adil Haseeb, Thadeo Trivilegio, Alshaimaa Alhallaj, Saleh Alghamdi, Abdul-Wali Ajlouni and Sabine Matou-Nasri
    Citation: BMC Complementary Medicine and Therapies 2020 20:154
    Content type: Research article Published on:

  39. This study was aimed at investigating the possible anti-inflammatory and cytotoxic effects of extracts from the flowering stage of C. argentea. This growth stage was chosen because of its high polyphenolic conten...

    Authors: Oluwafunmilayo Dorcas Adegbaju, Gloria Aderonke Otunola and Anthony Jide Afolayan
    Citation: BMC Complementary Medicine and Therapies 2020 20:152
    Content type: Research article Published on:

  40. Chinese herbal medicine is widely used in combination with usual care for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in China. Chinese patent medicine Shufeng Jiedu (SFJD) capsules i...

    Authors: Ru-yu Xia, Xiao-yang Hu, Yu-tong Fei, Merlin Willcox, Ling-zi Wen, Ming-kun Yu, Li-shan Zhang, Meng-yuan Dai, Guang-he Fei, Mike Thomas, Nick Francis, Tom Wilkinson, Michael Moore and Jian-ping Liu
    Citation: BMC Complementary Medicine and Therapies 2020 20:151
    Content type: Research article Published on:

  41. Our previous study revealed the extract from the bark of an Amazonian tree Pao Pereira can suppress benign prostatic hyperplasia (BPH) in a rat model. Herein, we examined its inhibitory effects on human BPH ce...

    Authors: Yu Dong, Jiakuan Liu, Zesheng Xue, Jingya Sun, Zhengnan Huang, Yifeng Jing, Bangmin Han, Bing Shen, Jun Yan and Ruimin Huang
    Citation: BMC Complementary Medicine and Therapies 2020 20:150
    Content type: Research article Published on:

  42. Currently there is a high prevalence of humor disorders such as anxiety and depression throughout the world, especially concerning advanced age patients. Aniba riparia (Nees) Mez. (Lauraceae), popular known as “l...

    Authors: Sócrates Golzio dos Santos, Isis Fernandes Gomes, Adriana Maria Fernandes de Oliveira Golzio, Augusto Lopes Souto, Marcus Tullius Scotti, Josean Fechine Tavares, Stanley Juan Chavez Gutierrez, Reinaldo Nóbrega de Almeida, José Maria Barbosa-Filho and Marcelo Sobral da Silva
    Citation: BMC Complementary Medicine and Therapies 2020 20:149
    Content type: Research article Published on:

  43. Most clinical investigations involving yoga lack adequate description of the specific yoga elements, including physical postures. Few studies have measured self-efficacy regarding the performance of yoga postu...

    Authors: Francesca M. Nicosia, Nadra E. Lisha, Margaret A. Chesney, Leslee L. Subak, Traci M. Plaut and Alison Huang
    Citation: BMC Complementary Medicine and Therapies 2020 20:148
    Content type: Research article Published on:

  44. The 2015 MERS outbreak in South Korea was the largest event outside of the Middle East. Under such circumstances, individuals tend to resort to non-conventional solutions such as complementary and alternative ...

    Authors: Jung Hye Hwang, Hyun Jeong Cho, Hyea Bin Im, Young Sun Jung, Soo Jeung Choi and Dongwoon Han
    Citation: BMC Complementary Medicine and Therapies 2020 20:147
    Content type: Research article Published on:

  45. Acute radiation-induced proctitis (ARP) is the most common side effect following radiotherapy for malignant pelvic disease. This study evaluated the efficacy of Aloe vera ointment in prevention of ARP.

    Authors: Adeleh Sahebnasagh, Arash Ghasemi, Jafar Akbari, Abbas Alipour, Hossein Lashkardoost, Shahram Ala, Seyed Jalal Hosseinimehr and Ebrahim Salehifar
    Citation: BMC Complementary Medicine and Therapies 2020 20:146
    Content type: Research article Published on:

  46. Myrrh (Commiphora myrrha (Nees) Engl.) has a long history of traditional use as a herbal medicine for different purposes. In ancient traditional Persian manuscripts, it has been noted that myrrh may act as ute...

    Authors: Homeira Vafaei, Sara Ajdari, Kamran Hessami, Ayda Hosseinkhani, Leila Foroughinia, Nasrin Asadi, Azam Faraji, Sepideh Abolhasanzadeh, Khadije Bazrafshan and Shohreh Roozmeh
    Citation: BMC Complementary Medicine and Therapies 2020 20:145
    Content type: Research article Published on:

  47. Dermal papilla cells (DPCs) play a key role in hair growth among the various cell types in hair follicles. Especially, DPCs determine the fate of hair follicle such as anagen to telogen transition and play a p...

    Authors: Jae Young Shin, Yun-Ho Choi, Jaeyoon Kim, Se Young Park, You Jin Nam, So Young Lee, Jeong Hoon Jeon, Mu Hyun Jin and Sanghwa Lee
    Citation: BMC Complementary Medicine and Therapies 2020 20:144
    Content type: Research article Published on:

  48. Elaeagnus umbellata is abundantly found in Himalayan regions of Pakistan which is traditionally used to treat various health disorders. However, the experimental evidence supporting the anti-amnesic effect is lim...

    Authors: Nausheen Nazir, Muhammad Zahoor, Mohammad Nisar, Nasiara Karim, Abdul Latif, Sajjad Ahmad and Zia Uddin
    Citation: BMC Complementary Medicine and Therapies 2020 20:143
    Content type: Research article Published on:

  49. Carvacrol is a food additive with various bioactivities, including reducing the blood glucose level as well as improvement of heart function, in diabetic mice. We explored the antihyperglycemic effect of carva...

    Authors: Yilang Li, Yunpei Mai, Xiaoxia Qiu, Xiaoqing Chen, Conglin Li, Wenchang Yuan and Ning Hou
    Citation: BMC Complementary Medicine and Therapies 2020 20:142
    Content type: Research article Published on:

  50. The development and growth of colorectal cancer based on constitutive activation of numerous signaling pathways that stimulate proliferation and metastasis. Plant-derived agents excel by targeting multiple asp...

    Authors: Marta Woźniak, Sebastian Makuch, Kinga Winograd, Jerzy Wiśniewski, Piotr Ziółkowski and Siddarth Agrawal
    Citation: BMC Complementary Medicine and Therapies 2020 20:141
    Content type: Research article Published on:
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ISSN: 2662-7671

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