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  1. Propolis is a natural product of plant resins collected by honeybees (Apis mellifera) from various plant sources. Our previous studies indicated that propolis sensitivity is dependent on the mitochondrial functio...

    Authors: Patrícia Alves de Castro, Marcela Savoldi, Diego Bonatto, Iran Malavazi, Maria Helena S Goldman, Andresa A Berretta and Gustavo Henrique Goldman
    Citation: BMC Complementary and Alternative Medicine 2012 12:194
  2. The overall prevalence of complementary medicine (CM) use among adults in the United States with diabetes has been examined both in representative national samples and in more restricted populations. However, ...

    Authors: Richard L Nahin, Danita Byrd-Clark, Barbara J Stussman and Nilesh Kalyanaraman
    Citation: BMC Complementary and Alternative Medicine 2012 12:193
  3. Brazilian green propolis is reported to have wide range of biological properties including antibacterial, anti-inflammatory, anti-influenza, and antioxidant activities. In the digestive system, a protective ef...

    Authors: Mamoru Kakino, Hiroshi Izuta, Kazuhiro Tsuruma, Yoko Araki, Masamitsu Shimazawa, Kenji Ichihara and Hideaki Hara
    Citation: BMC Complementary and Alternative Medicine 2012 12:192
  4. This paper proposes a novel model for homeopathic remedy action on living systems. Research indicates that homeopathic remedies (a) contain measurable source and silica nanoparticles heterogeneously dispersed ...

    Authors: Iris R Bell and Mary Koithan
    Citation: BMC Complementary and Alternative Medicine 2012 12:191
  5. Nuna Kadugu (NK), a Siddha medicine prepared from leaves and fruits of Morinda Pubescens, used for the treatment of various skin diseases. Though NK has been widely used for several decades, no scientific report ...

    Authors: Ramaswamy Selvaratnam Ramaswamy, Nettam Prathyusha, Ruthiramoorthi Saranya, Haridass Sumathy, Kutuva Tulasi Mohanavalli, Raju Jyothi Priya, Jayakothanda Ramaswamy Venkhatesh, Chidambaram Saravana Babu, Kumarasamy Manickavasakam and Sadagopan Thanikachalam
    Citation: BMC Complementary and Alternative Medicine 2012 12:190
  6. Our previous studies indicated that oxidative stress up-regulated the expression of β-amyloid precursor protein cleavage enzyme-1 (BACE1) in rat retina. Pharmacological reports have shown Timosaponin-BII, a pu...

    Authors: Ju-Fang Huang, Lei Shang, Pei Liu, Meng-Qi Zhang, Shuang Chen, Dan Chen, Chun-Ling Fan, Hui Wang and Kun Xiong
    Citation: BMC Complementary and Alternative Medicine 2012 12:189
  7. Diabetes is one of the risk factors for cognitive deficits such as Alzheimer’s disease. To obtain a better understanding of the anti-dementia effect of chotosan (CTS), a Kampo formula, we investigated its effe...

    Authors: Qi Zhao, Yimin Niu, Kinzo Matsumoto, Koichi Tsuneyama, Ken Tanaka, Takeshi Miyata and Takako Yokozawa
    Citation: BMC Complementary and Alternative Medicine 2012 12:188
  8. Selaginella convoluta (Arn.) Spring (Selaginellaceae), commonly known as “jericó”, is a medicinal plant found in northeastern Brazil. S. convoluta is used in folk medicine as an antidepressant, aphrodisiac, diur...

    Authors: Pedro Guilherme S de Sá, Xirley Pereira Nunes, Julianeli Tolentino de Lima, JoséAlvesdeSiqueira Filho, André Paviotti Fontana, Jullyana de Souza Siqueira, Lucindo José Quintans-Júnior, Patrícia Kauanna Fonseca Damasceno, Carla Rodrigues Cardoso Branco, Alexsandro Branco and JacksonRobertoGuedesdaSilva Almeida
    Citation: BMC Complementary and Alternative Medicine 2012 12:187
  9. Noni fruit is widely consumed in tropical regions of Indonesia to the Hawaiian Islands. The noni plant has a long history of use as a medicinal plant to treat a wide variety of ailments including CNS disorders...

    Authors: Vijayapandi Pandy, Megala Narasingam and Zahurin Mohamed
    Citation: BMC Complementary and Alternative Medicine 2012 12:186
  10. Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from the Thai medicinal plant Trichosanthes cucumerina L., has been reported to have several biological activities including anti-inflamma...

    Authors: Suwit Duangmano, Phorntip Sae-lim, Apichart Suksamrarn, Frederick E Domann and Pimpicha Patmasiriwat
    Citation: BMC Complementary and Alternative Medicine 2012 12:185
  11. Cupping is used in various traditional medicine forms to relieve pain in musculoskeletal diseases. The aim of this study was to investigate the effectiveness of cupping in relieving the symptoms of knee osteoa...

    Authors: Michael Teut, Stefan Kaiser, Miriam Ortiz, Stephanie Roll, Sylvia Binting, Stefan N Willich and Benno Brinkhaus
    Citation: BMC Complementary and Alternative Medicine 2012 12:184
  12. Complementary medicines (CMs) are widely used by the Australian public, and pharmacies are major suppliers of these medicines. The integration of CMs into pharmacy practice is well documented, but the behaviou...

    Authors: Sarah E Culverhouse and Hans Wohlmuth
    Citation: BMC Complementary and Alternative Medicine 2012 12:183
  13. United States Army Soldiers regularly use dietary supplements (DS) to promote general health, enhance muscle strength, and increase energy, but limited scientific evidence supports the use of many DS for these...

    Authors: Christina E Carvey, Emily K Farina and Harris R Lieberman
    Citation: BMC Complementary and Alternative Medicine 2012 12:182
  14. Sonchus asper (L.) Hill, (Asteraceae) is used in Pakistan as a traditional (“folk”) medicine for the treatment of hormonal disorders and oxidative stress. The present study was aimed to evaluate the efficacy of

    Authors: Rahmat Ali Khan
    Citation: BMC Complementary and Alternative Medicine 2012 12:181
  15. Patients with stroke have various syndromes and symptoms. Through pattern identification (PI), traditional Korean medicine (TKM) classifies the several syndromes and symptoms of stroke patients into five categ...

    Authors: Ji Hye Lim, Mi Mi Ko, Tae-Woong Moon, Min Ho Cha and Myeong Soo Lee
    Citation: BMC Complementary and Alternative Medicine 2012 12:180
  16. Oral cancers although preventable, possess a low five-year survival rate which has remained unchanged over the past three decades. In an attempt to find a more safe, affordable and effective treatment option, ...

    Authors: Lionel LA In, Norhafiza M Arshad, Halijah Ibrahim, Mohamad Nurul Azmi, Khalijah Awang and Noor Hasima Nagoor
    Citation: BMC Complementary and Alternative Medicine 2012 12:179
  17. Rutin is a polyphenolic natural flavonoid which possesses antioxidant and anticancer activity. In the present study the hepatoprotective effect of rutin was evaluated against carbon tetrachloride (CCl4)-induced l...

    Authors: Rahmat A Khan, Muhammad R Khan and Sumaira Sahreen
    Citation: BMC Complementary and Alternative Medicine 2012 12:178
  18. There is no available information on physicochemical and antioxidant properties on Bangladeshi honey. We investigated five different monofloral and three different multifloral honey samples collected from diff...

    Authors: Asiful Islam, Ibrahim Khalil, Nazmul Islam, Mohammed Moniruzzaman, Abdul Mottalib, Siti Amrah Sulaiman and Siew Hua Gan
    Citation: BMC Complementary and Alternative Medicine 2012 12:177
  19. In the present study, we tested a 50% ethanolic extract of Orthosiphon stamineus plants and its isolated bioactive compound with respect to their α-glucosidase and α-amylase inhibitory activities.

    Authors: Elsnoussi Ali Hussin Mohamed, Mohammad Jamshed Ahmad Siddiqui, Lee Fung Ang, Amirin Sadikun, Sue Hay Chan, Soo Choon Tan, Mohd Zaini Asmawi and Mun Fei Yam
    Citation: BMC Complementary and Alternative Medicine 2012 12:176
  20. Withania somnifera, also known as ashwagandha, is an important herb in ayurvedic and indigenous medical systems. The present study was designed to evaluate the antioxidant and antibacterial activities of an 80% ...

    Authors: Nadia Alam, Monzur Hossain, Md Abdul Mottalib, Siti Amrah Sulaiman, Siew Hua Gan and Md Ibrahim Khalil
    Citation: BMC Complementary and Alternative Medicine 2012 12:175
  21. The essential oil from Fructus Alpiniae zerumbet (FAZ) is its principal bioactive ingredient, and is widely used in Miao folk herbs in Guizhou province for the treatment of gastrointestinal and cardiovascular dis...

    Authors: Xiang-chun Shen, Ling Tao, Wan-kui Li, Yan-yan Zhang, Hong Luo and Yu-yi Xia
    Citation: BMC Complementary and Alternative Medicine 2012 12:174
  22. The main aim of this study is to evaluate the antioxidant and anti-inflammatory properties of forty four traditional Chinese medicinal herbal extracts and to examine these activities in relation to their antio...

    Authors: Anjaneya S Ravipati, Lin Zhang, Sundar Rao Koyyalamudi, Sang Chul Jeong, Narsimha Reddy, John Bartlett, Paul T Smith, Kirubakaran Shanmugam, Gerald Münch, Ming Jie Wu, Manavalan Satyanarayanan and Balaram Vysetti
    Citation: BMC Complementary and Alternative Medicine 2012 12:173
  23. Mistletoe (Viscum album L.) extracts are widely used in complementary cancer therapy. Aim of this study was to evaluate safety and efficacy of a standardized mistletoe extract (abnobaVISCUM® Quercus, aVQ) in p...

    Authors: Kab-Choong Kim, Jeong-Hwan Yook, Jürgen Eisenbraun, Byung-Sik Kim and Roman Huber
    Citation: BMC Complementary and Alternative Medicine 2012 12:172
  24. This study aims to investigate anti-inflammatory effect of ethanolic extract of Myagropsis myagroides (EMM) in the lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages and the phorbol 12-myristate 13-acetate...

    Authors: Eun-Ji Joung, Min-Sup Lee, Ji-Woong Choi, Jong-Soon Kim, Taisun Shin, Bok-Mi Jung, Na Young Yoon, Chi-Won Lim, Jae-Il Kim and Hyeung-Rak Kim
    Citation: BMC Complementary and Alternative Medicine 2012 12:171
  25. A dried root of Aristolochia tagala Cham. (ATC) is often used in Thai traditional medicine as an antipyretic, anti-inflammatory agent, muscle relaxant, appetite-enhancing agent, and analeptic. Homnawakod, an impo...

    Authors: Pinpat Tripatara, Winita Onlamul, Suksalin Booranasubkajorn, Jantanee Wattanarangsan, Sukit Huabprasert, Natchagorn Lumlerdkij, Pravit Akarasereenont and Tawee Laohapand
    Citation: BMC Complementary and Alternative Medicine 2012 12:170
  26. Mycoplasmosis is a common infection in human and veterinary medicine, and is associated with chronic inflammation and high morbidity. Mycoplasma species are often intrinsically resistant to many conventional anti...

    Authors: Amanda V Arjoon, Charlotte V Saylor and Meghan May
    Citation: BMC Complementary and Alternative Medicine 2012 12:169
  27. The leaves and root of Flabellaria paniculata (Malpighiaceae) are frequently used in the treatment of wounds and ulcers in Nigerian folk medicine. The purpose of this study was to compare the effect of ethanolic ...

    Authors: Margaret O Sofidiya, Lilian Agufobi, Abidemi J Akindele, Johnson A Olowe and Oluwole B Familoni
    Citation: BMC Complementary and Alternative Medicine 2012 12:168
  28. Difficulty in controlling attention can lead to mental fatigue in the healthy population. We identified one trial reporting a benefit in patients’ attention using a homeopathic formula preparation. One compone...

    Authors: Michael Emmans Dean, Raj Karsandas, J Martin Bland, Debbie Gooch and Hugh MacPherson
    Citation: BMC Complementary and Alternative Medicine 2012 12:167
  29. The aqueous-methanolic extract of Amaranthus spinosus (A. spinosus Linn.,) whole plant, was studied for its laxative, spasmolytic and bronchodilator activities to validate some of its medicinal uses.

    Authors: Mueen Ahmad Chaudhary, Imran Imran, Samra Bashir, Malik Hassan Mehmood, Najeeb-ur Rehman and Anwarul-Hassan Gilani
    Citation: BMC Complementary and Alternative Medicine 2012 12:166
  30. Many indigenous plants of Mascarene Islands have been used in folkloric medicine to manage diabetes but few species have received scientific attention. Selected traditional medicinal plants (Antidesma madagascari...

    Authors: Fawzi M Mahomoodally, Anwar H Subratty, Ameenah Gurib-Fakim and Muhammad Iqbal Choudhary
    Citation: BMC Complementary and Alternative Medicine 2012 12:165
  31. Prenatal use of traditional medicine or complementary and alternative medicine is widespread globally despite the lack of evidence of the effectiveness of these therapeutic options. Documentation on the preval...

    Authors: Dudzai D Mureyi, Tsitsi G Monera and Charles C Maponga
    Citation: BMC Complementary and Alternative Medicine 2012 12:164
  32. Records have shown that Combretum adenogonium Steud. Ex A. Rich (Combretaceae) is used in traditional medicine systems of several tribes in Tanzania. This study focused on the investigation of antibacterial activ...

    Authors: Novatus F Mushi, Zakaria H Mbwambo, Ester Innocent and Supinya Tewtrakul
    Citation: BMC Complementary and Alternative Medicine 2012 12:163
  33. Mindfulness-based stress reduction (MBSR) is frequently used for pain conditions. While systematic reviews on MBSR for chronic pain have been conducted, there are no reviews for specific pain conditions. There...

    Authors: Holger Cramer, Heidemarie Haller, Romy Lauche and Gustav Dobos
    Citation: BMC Complementary and Alternative Medicine 2012 12:162
  34. Chronic knee pain is a common and disabling condition in people over 50 years of age, with knee joint osteoarthritis being a major cause. Acupuncture is a popular form of complementary and alternative medicine...

    Authors: Rana S Hinman, Paul McCrory, Marie Pirotta, Ian Relf, Kay M Crossley, Prasuna Reddy, Andrew Forbes, Anthony Harris, Ben R Metcalf, Mary Kyriakides, Kitty Novy and Kim L Bennell
    Citation: BMC Complementary and Alternative Medicine 2012 12:161
  35. Our ongoing research has revealed that total saponins extracted from the medicinal herb Radix Astragali (AST) exhibits significant growth-inhibitory and proapoptotic effects in human cancer cells. In the prese...

    Authors: Pui-Ching Law, Kathy K Auyeung, Lok-Yi Chan and Joshua K Ko
    Citation: BMC Complementary and Alternative Medicine 2012 12:160
  36. Complementary and alternative medicine (CAM) is becoming a popular treatment for modulating diverse immune disorders. Phellinus linteus (P. linteus) as one of the CAMs has been used to modulate cancers, inflammat...

    Authors: Ji Sun Hwang, Ho-Keun Kwon, Jung-Eun Kim, Jeonghae Rho and Sin-Hyeog Im
    Citation: BMC Complementary and Alternative Medicine 2012 12:159
  37. Despite the growing popularity of massage, its effectiveness for treating neck pain remains unclear, largely because of the poor quality of research. A major deficiency of previous studies has been their use o...

    Authors: Karen J Sherman, Andrea J Cook, Janet R Kahn, Rene J Hawkes, Robert D Wellman and Daniel C Cherkin
    Citation: BMC Complementary and Alternative Medicine 2012 12:158
  38. Abnormal Savda Munziq (ASMq), a traditional uyghur medicine, has shown anti-tumour properties in vitro. This study attempts to confirm these effects in vivo and measure effects on the immune system.

    Authors: Ainiwaer Aikemu, Anwar Umar, Abdiryim Yusup, Halmurat Upur, Bénédicte Berké, Bernard Bégaud and Nicholas Moore
    Citation: BMC Complementary and Alternative Medicine 2012 12:157
  39. At present there is no effective and accepted therapy for hepatic fibrosis. Transforming growth factor (TGF)-β1 signaling pathway contributes greatly to hepatic fibrosis. Reducing TGF-β synthesis or inhibiting...

    Authors: Qun-yan Yao, Bei-li Xu, Ji-yao Wang, Hong-chun Liu, Shun-cai Zhang and Chuan-tao Tu
    Citation: BMC Complementary and Alternative Medicine 2012 12:156
  40. Evidence is lacking for multi-ingredient herbal supplements claiming therapeutic effect in sexual dysfunction in men. We examined the safety and efficacy of VigRX Plus (VXP) – a proprietary polyherbal preparat...

    Authors: Gaurang R Shah, Manojkumar V Chaudhari, Suresh B Patankar, Shrikant V Pensalwar, Vilas P Sabale and Navneet A Sonawane
    Citation: BMC Complementary and Alternative Medicine 2012 12:155
  41. Type 2 diabetes (T2D) is a complex metabolic disorder characterized by insulin resistance and hyperglycemia. Peroxisome proliferator-activated receptor gamma (PPARγ) is a key transcription factor and plays an ...

    Authors: Yunkyung Han, Hyo Won Jung and Yong-Ki Park
    Citation: BMC Complementary and Alternative Medicine 2012 12:154
  42. Plants play a significant role in maintaining human health and improving the quality of human life. They serve humans well as valuable components of food, as well as in cosmetics, dyes, and medicines. In fact,...

    Authors: Fadwa Chaabane, Jihed Boubaker, Amira Loussaif, Aicha Neffati, Somaya Kilani-Jaziri, Kamel Ghedira and Leila Chekir-Ghedira
    Citation: BMC Complementary and Alternative Medicine 2012 12:153
  43. Eurycoma longifolia (EL) has been shown recently to protect against bone calcium loss in orchidectomised rats, the model for androgen-deficient osteoporosis. The mechanism behind this is unclear but it may be re...

    Authors: Ahmad Nazrun Shuid, Eman El-arabi, Nadia Mohd Effendy, Halimaton Saadiah Abdul Razak, Norliza Muhammad, Norazlina Mohamed and Ima Nirwana Soelaiman
    Citation: BMC Complementary and Alternative Medicine 2012 12:152
  44. The leaves of Caylusea abyssinica (fresen.) Fisch. & Mey. (Resedaceae), a plant widely distributed in East African countries, have been used for management of diabetes mellitus in Ethiopian folklore medicine. How...

    Authors: Wondmagegn Tamiru, Ephrem Engidawork and Kaleab Asres
    Citation: BMC Complementary and Alternative Medicine 2012 12:151
  45. Homeopathy is widely used, and many European physicians practice homeopathy in addition to conventional medicine. Adverse effects in homeopathy are not expected by homeopaths due to the negligible quantities o...

    Authors: Trine Stub, Terje Alræk and Anita Salamonsen
    Citation: BMC Complementary and Alternative Medicine 2012 12:150
  46. Kalanchoe tubiflora (KT) is a succulent plant native to Madagascar, and is commonly used as a medicinal agent in Southern Brazil. The underlying mechanisms of tumor suppression are largely unexplored.

    Authors: Yi-Jen Hsieh, Ming-Yeh Yang, Yann-Lii Leu, Chinpiao Chen, Chin-Fung Wan, Meng-Ya Chang and Chih-Jui Chang
    Citation: BMC Complementary and Alternative Medicine 2012 12:149
  47. There is a need for more Comparative Effectiveness Research (CER) to strengthen the evidence base for clinical and policy decision-making. Effectiveness Guidance Documents (EGD) are targeted to clinical resear...

    Authors: Claudia M Witt, Mikel Aickin, Trini Baca, Dan Cherkin, Mary N Haan, Richard Hammerschlag, Jason Jishun Hao, George A Kaplan, Lixing Lao, Terri McKay, Beverly Pierce, David Riley, Cheryl Ritenbaugh, Kevin Thorpe, Sean Tunis, Jed Weissberg…
    Citation: BMC Complementary and Alternative Medicine 2012 12:148
  48. Common cold is caused by a variety of respiratory viruses. The prevalence in children is high, and it potentially contributes to significant morbidity. Iota-carragenan, a polymer derived from red seaweed, has ...

    Authors: Tamas Fazekas, Philipp Eickhoff, Nathalie Pruckner, Georg Vollnhofer, Gustav Fischmeister, Christopher Diakos, Margit Rauch, Maria Verdianz, Andreas Zoubek, Helmut Gadner and Thomas Lion
    Citation: BMC Complementary and Alternative Medicine 2012 12:147
  49. Traditional Chinese Medicine (TCM) is one of the most popular complementary and alternative medicine modalities worldwide. In Chinese and East Asian societies, TCM plays an active role in the modern health car...

    Authors: Yueh-Hsiang Liao, Cheng-Chieh Lin, Tsai-Chung Li and Jaung-Geng Lin
    Citation: BMC Complementary and Alternative Medicine 2012 12:146
  50. Obesity is recognized as a social problem, associated with serious health risks and increased mortality. Numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to...

    Authors: Neerja Rani, Neeru Vasudeva and Surendra Kumar Sharma
    Citation: BMC Complementary and Alternative Medicine 2012 12:145