Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation

Table 1 Basic information of 15 core targets

NO.	Uniprot ID	Gene symbol	Protein name	Degree
1	P31749	AKT1	RAC-alpha serine/threonine-protein kinase	72
2	P04637	TP53	Cellular tumor antigen p53	69
3	P15692	VEGFA	Vascular endothelial growth factor A	67
4	P12931	SRC	Proto-oncogene tyrosine-protein kinase Src	64
5	P42574	CASP3	Caspase 3	64
6	P01112	HRAS	HRas Proto-Oncogene, GTPase	60
7	P00533	EGFR	Epidermal growth factor receptor	59
8	P03372	ESR1	Estrogen receptor	56
9	Q16665	HIF1A	Hypoxia-inducible factor 1-alpha	56
10	P42345	MTOR	Serine/threonine-protein kinase mTOR	53
11	P37231	PPARG	Peroxisome proliferator activated receptor gamma	51
12	P35354	PTGS2	Prostaglandin G/H synthase 2	50
13	P01100	FOS	Transcription factor AP-1	49
14	P14780	MMP9	Matrix metalloproteinase-9	48
15	Q07817	BCL2L1	Apoptosis regulator Bcl-2	47

ISSN: 2662-7671